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2. Characteristics Associated with Hospitalization Among Patients with COVID-19 — Metropolitan Atlanta, Georgia, March–April 2020

Author

CDC COVID-19 Response Clinical Team, Killerby, Marie E., Link-Gelles, Ruth, Haight, Sarah C., Schrodt, Caroline A., England, Lucinda, Gomes, Danica J., Shamout, Mays, Pettrone, Kristen, O’Laughlin, Kevin, Kimball, Anne, Blau, Erin F., Burnett, Eleanor, Ladva, Chandresh N., Szablewski, Christine M., Tobin-D’Angelo, Melissa, Oosmanally, Nadine, Drenzek, Cherie, Murphy, David J., Blum, James M., Hollberg, Julie, Lefkove, Benjamin, Brown, Frank W., Shimabukuro, Tom, Midgley, Claire M., and Tate, Jacqueline E.

Published
2020

3. Characteristics and Clinical Outcomes of Adult Patients Hospitalized with COVID-19 — Georgia, March 2020

Author

Gold, Jeremy A. W., Wong, Karen K., Szablewski, Christine M., Patel, Priti R., Rossow, John, da Silva, Juliana, Natarajan, Pavithra, Morris, Sapna Bamrah, Fanfair, Robyn Neblett, Rogers-Brown, Jessica, Bruce, Beau B., Browning, Sean D., Hernandez-Romieu, Alfonso C., Furukawa, Nathan W., Kang, Mohleen, Evans, Mary E., Oosmanally, Nadine, Tobin-D’Angelo, Melissa, Drenzek, Cherie, Murphy, David J., Hollberg, Julie, Blum, James M., Jansen, Robert, Wright, David W., Sewell, William M., Owens, Jack D., Lefkove, Benjamin, Brown, Frank W., Burton, Deron C., Uyeki, Timothy M., Bialek, Stephanie R., and Jackson, Brendan R.

Published
2020

4. Characteristics and Risk Factors of Hospitalized and Nonhospitalized COVID-19 Patients, Atlanta, Georgia, USA, March-April 2020

Author

Pettrone, Kristen, Burnett, Eleanor, Link-Gelles, Ruth, Haight, Sarah C., Schrodt, Caroline, England, Lucinda, Gomes, Danica J., Shamout, Mays, O'Laughlin, Kevin, Kimball, Anne, Blau, Erin F., Ladva, Chandresh N., Szablewski, Christine M., Tobin-DAngelo, Melissa, Oosmanally, Nadine, Drenzek, Cherie, Browning, Sean D., Bruce, Beau B., Silva, Juliana da, Gold, Jeremy A.W., Jackson, Brendan R., Morris, Sapna Bamrah, Natarajan, Pavithra, Fanfair, Robyn Neblett, Patel, Priti R., Rogers- Brown, Jessica, Rossow, John, Wong, Karen K., Murphy, David J., Blum, James M., Hollberg, Julie, Lefkove, Benjamin, Brown, Frank W., Shimabukuro, Tom, Midgley, Claire M., Tate, Jacqueline E., and Killerby, Marie E.

Subjects
Epidemics -- Risk factors -- Patient outcomes -- Demographic aspects -- United States, Health
Abstract

Information about care-seeking behavior, symptom duration, and risk factors for progression to severe illness in nonhospitalized patients with coronavirus disease (COVID-19) aids in resource planning, disease identification, risk stratification, and [...]

Published
2021
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19. Characteristics Associated with Hospitalization Among Patients with COVID-19 — Metropolitan Atlanta, Georgia, March–April 2020

Author

Killerby, Marie E., Link-Gelles, Ruth, Haight, Sarah C., Schrodt, Caroline A., England, Lucinda, Gomes, Danica J., Shamout, Mays, Pettrone, Kristen, O'Laughlin, Kevin, Kimball, Anne, Blau, Erin F., Burnett, Eleanor, Ladva, Chandresh N., Szablewski, Christine M., Tobin-D’Angelo, Melissa, Oosmanally, Nadine, Drenzek, Cherie, Murphy, David J., Blum, James M., Hollberg, Julie, Lefkove, Benjamin, Brown, Frank W., Shimabukuro, Tom, Midgley, Claire M., Tate, Jacqueline E., Browning, Sean D., Bruce, Beau B., da Silva, Juliana, Gold, Jeremy A.W., Jackson, Brendan R., Bamrah Morris, Sapna, Natarajan, Pavithra, Neblett Fanfair, Robyn, Patel, Priti R., Rogers-Brown, Jessica, Rossow, John, and Wong, Karen K.

Subjects
Adult, Male, medicine.medical_specialty, Health (social science), Georgia, Adolescent, Epidemiology, Health, Toxicology and Mutagenesis, Pneumonia, Viral, Disease, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Health Information Management, Risk Factors, 030225 pediatrics, Acute care, Diabetes mellitus, medicine, Outpatient clinic, Humans, 030212 general & internal medicine, Full Report, Young adult, Cities, Pandemics, Aged, business.industry, Medical record, COVID-19, General Medicine, Odds ratio, Middle Aged, medicine.disease, Hospitalization, Emergency medicine, Female, business, Coronavirus Infections, Kidney disease
Abstract

The first reported U.S. case of coronavirus disease 2019 (COVID-19) was detected in January 2020 (1). As of June 15, 2020, approximately 2 million cases and 115,000 COVID-19-associated deaths have been reported in the United States.* Reports of U.S. patients hospitalized with SARS-CoV-2 infection (the virus that causes COVID-19) describe high proportions of older, male, and black persons (2-4). Similarly, when comparing hospitalized patients with catchment area populations or nonhospitalized COVID-19 patients, high proportions have underlying conditions, including diabetes mellitus, hypertension, obesity, cardiovascular disease, chronic kidney disease, or chronic respiratory disease (3,4). For this report, data were abstracted from the medical records of 220 hospitalized and 311 nonhospitalized patients aged ≥18 years with laboratory-confirmed COVID-19 from six acute care hospitals and associated outpatient clinics in metropolitan Atlanta, Georgia. Multivariable analyses were performed to identify patient characteristics associated with hospitalization. The following characteristics were independently associated with hospitalization: age ≥65 years (adjusted odds ratio [aOR] = 3.4), black race (aOR = 3.2), having diabetes mellitus (aOR = 3.1), lack of insurance (aOR = 2.8), male sex (aOR = 2.4), smoking (aOR = 2.3), and obesity (aOR = 1.9). Infection with SARS-CoV-2 can lead to severe outcomes, including death, and measures to protect persons from infection, such as staying at home, social distancing (5), and awareness and management of underlying conditions should be emphasized for those at highest risk for hospitalization with COVID-19. Measures that prevent the spread of infection to others, such as wearing cloth face coverings (6), should be used whenever possible to protect groups at high risk. Potential barriers to the ability to adhere to these measures need to be addressed.

Published
2020

21. eARDS: A multi-center validation of an interpretable machine learning algorithm of early onset Acute Respiratory Distress Syndrome (ARDS) among critically ill adults with COVID-19

Author

Singhal, Lakshya, primary, Garg, Yash, additional, Yang, Philip, additional, Tabaie, Azade, additional, Wong, A. Ian, additional, Mohammed, Akram, additional, Chinthala, Lokesh, additional, Kadaria, Dipen, additional, Sodhi, Amik, additional, Holder, Andre L., additional, Esper, Annette, additional, Blum, James M., additional, Davis, Robert L., additional, Clifford, Gari D., additional, Martin, Greg S., additional, and Kamaleswaran, Rishikesan, additional

Published
2021
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22. Secondary Bacterial Pneumonias and Bloodstream Infections in Patients Hospitalized with COVID-19

Author

Adelman, Max W., primary, Bhamidipati, Divya R., additional, Hernandez-Romieu, Alfonso C., additional, Babiker, Ahmed, additional, Woodworth, Michael H., additional, Robichaux, Chad, additional, Murphy, David J., additional, Auld, Sara C., additional, Kraft, Colleen S., additional, Jacob, Jesse T., additional, Adelman, Max W., additional, Arno, Scott, additional, Barnes, Theresa, additional, Bender, William, additional, Blum, James M., additional, Budhrani, Gaurav, additional, Busby, Stephanie, additional, Busse, Laurence, additional, Caridi-Scheible, Mark, additional, Carpenter, David, additional, Chaudhari, Nikulkumar, additional, Coopersmith, Craig M., additional, Dale, Gordon, additional, Daniels, Lisa, additional, Edwards, Johnathan A., additional, Fazio, Jane, additional, Fiza, Babar, additional, Gonzalez, Eliana, additional, Gripaldo, Ria, additional, Grodzin, Charles, additional, Groff, Robert, additional, Hockstein, Max, additional, Hunt, Dan, additional, Jabaley, Craig S., additional, Martin, Greg S., additional, Melham, Samer, additional, Mehta, Nirja, additional, Modlin, Chelsea, additional, Park, Jung, additional, Patel, Deepa, additional, Powell, Cindy, additional, Prabhakar, Amit, additional, Rim, Jeeyon, additional, Rimawi, Ramzy, additional, Scanlon, Nicholas, additional, Sharifpour, Milad, additional, Staitieh, Bashar, additional, Sterling, Michael, additional, Suarez, Jonathan, additional, Swenson, Colin, additional, Thakkar, Nancy, additional, Truong, Alexander, additional, Veeramachaneni, Hima, additional, Velasquez, Alvaro, additional, Vester, Aimee, additional, Waldmann, Michael, additional, Weinmann, Max, additional, Wynn, Thanushi, additional, and Zivot, Joel, additional

Published
2021
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25. Supplements of 20 [micro]g/d cholecalciferol optimized serum 25-hydroxyvitamin D concentrations in 80% of premenopausal women in winter

Author

Nelson, Monica L., Blum, James M., Hollis, Bruce W., Rosen, Clifford, and Sullivan, Susan S.

Subjects
Menopause -- Health aspects, Dietary supplements -- Influence, Vitamin D3 -- Health aspects, Serum -- Properties, Serum -- Health aspects, Winter -- Influence, Body composition -- Research, Women -- Health aspects, Women -- Research, Food/cooking/nutrition
Abstract

The serum 25-hydroxyvitamin D [25(OH)D] response to daily supplementation with 20 [micro]g cholecalciferol (D3) during winter in predominantly white premenopausal women living in Maine was measured and the effects of body composition and hormonal contraceptive use on baseline serum 25(OH)D concentrations and the response to supplementation were examined. A total of 112 women (22.2 [+ or -] 3.7 y old) received placebo from March 2005 until September 2005 when they were randomized to receive either placebo or 20/[micro]g/d D3 through February 2006. Eighty-six women completed the study. Actual mean D3 content of the supplements was 22/[micro]g per capsule. In February 2005 the serum 25(OH)D concentration was 62.0 [+ or -] 23.4 nmol/L (mean [+ or -] SD). Serum 25(OH)D concentrations increased by 35.3 [+ or -] 23.2 nmol/L from February 2005 to February 2006 in the treatment group, significantly more than the 10.9 [+ or -] 16.9 nmol/L increase in the placebo group. Treatment group, magnitude of summer increase in 25(OH)D, estrogen dose, and baseline serum 25(OH)D concentrations, but not body fat, were significant predictors of the 1-y change in 25(OH)D concentrations used to assess the magnitude of the response to supplementation. Daily supplementation with 20/[micro]g D3 during winter achieved optimal 25(OH)D concentrations ([greater than or equal to] 75 nmol/L) in 80% of participants, indicating that this dose is adequate to optimize vitamin D status in most young women in Maine.

Published
2009

26. Prediction of Acute Respiratory Failure Requiring Advanced Respiratory Support in Advance of Interventions and Treatment: A Multivariable Prediction Model From Electronic Medical Record Data

Author

Wong, An-Kwok I., primary, Kamaleswaran, Rishikesan, additional, Tabaie, Azade, additional, Reyna, Matthew A., additional, Josef, Christopher, additional, Robichaux, Chad, additional, de Hond, Anne A. H., additional, Steyerberg, Ewout W., additional, Holder, Andre L., additional, Nemati, Shamim, additional, Buchman, Timothy G., additional, and Blum, James M., additional

Published
2021
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27. COVID-19 Clinical Phenotypes: Presentation and Temporal Progression of Disease in a Cohort of Hospitalized Adults in Georgia, United States

Author

da Silva, Juliana F, primary, Hernandez-Romieu, Alfonso C, additional, Browning, Sean D, additional, Bruce, Beau B, additional, Natarajan, Pavithra, additional, Morris, Sapna B, additional, Gold, Jeremy A W, additional, Neblett Fanfair, Robyn, additional, Rogers-Brown, Jessica, additional, Rossow, John, additional, Szablewski, Christine M, additional, Oosmanally, Nadine, additional, D’Angelo, Melissa Tobin, additional, Drenzek, Cherie, additional, Murphy, David J, additional, Hollberg, Julie, additional, Blum, James M, additional, Jansen, Robert, additional, Wright, David W, additional, Sewell, William, additional, Owens, Jack, additional, Lefkove, Benjamin, additional, Brown, Frank W, additional, Burton, Deron C, additional, Uyeki, Timothy M, additional, Patel, Priti R, additional, Jackson, Brendan R, additional, and Wong, Karen K, additional

Published
2020
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33. Contributors

Author

Adhikary, Sanjib, primary, Aguilar, Jorge, additional, Ahere, Charles, additional, Ahmed, Moustafa, additional, Ahn, Jane C., additional, Akhtar, Shamsuddin, additional, Albert, David B., additional, Aldawoodi, Nasrin N., additional, Algren, John T., additional, Almeida-Chen, Gracie, additional, Amar, David, additional, Anastasian, Zirka H., additional, Aniskevich, Stephen, additional, Aronson, Solomon, additional, Arora, Harendra, additional, Asopa, Amit, additional, Atkins, Joshua H., additional, Augoustides, John G., additional, Azam, Mohammad Fareed, additional, Bachman, Catherine R., additional, Bacon, Douglas R., additional, Badley, Andrew D., additional, Baird, Emily, additional, Baldwin, Alethia, additional, Ball, Ryan, additional, Baluch, Amir, additional, Bandola, David, additional, Banks, Shawn, additional, Barash, Paul G., additional, Barrett, Kathleen E., additional, Beaman, Shawn T., additional, Beathe, Jonathan C., additional, Beatie, Christopher D., additional, Beattie, W. Scott, additional, Bechtle, Perry S., additional, Benzinger, G. Richard, additional, Berkow, Lauren, additional, Berman, Jeffrey M., additional, Bernstein, Wendy K., additional, Berry, Arnold J., additional, Berry, Frederic, additional, Berth, Ulrike, additional, Bethune, Walter, additional, Bhambhani, Sumita, additional, Bharadwaj, Shobana, additional, Bhatt, Neil, additional, Billings, Frederic T., additional, Binstock, Wendy B., additional, Birnbach, David J., additional, Bishop, Michael, additional, Black, Stephanie, additional, Blanchette, Mary A., additional, Blum, James M., additional, Boddu, Krishna, additional, Bonasera, Lara, additional, Boortz-Marx, Richard L., additional, Borel, Cecil O., additional, Botz, Gregory H., additional, Boucek, Charles D., additional, Bradford, William, additional, Brainard, Jason C., additional, Braunfeld, Michelle, additional, Braveman, Ferne R., additional, Bravo-Fernandez, Caridad, additional, Breen, Peter H., additional, Brennan, Marjorie, additional, Brentjens, Tricia, additional, Brockel, Megan A., additional, Brodsky, Jay B., additional, Bromberg, Todd A., additional, Broussard, Adam J., additional, Broussard, Chris, additional, Labrie-Brown, Carmen, additional, Brown, Robert H., additional, Brudney, Charles S., additional, Brull, Sorin J., additional, Brunson, Claude, additional, Bryson, Trent, additional, Buchowski, Jacob M., additional, Budac, Stefan, additional, Bush, Zachary D., additional, Butterworth, John, additional, Calo, Lisbeysi, additional, Canlas, Christopher, additional, Cannon, Ayana, additional, Cantie, Shawn M., additional, Caplan, Lisa, additional, Caruso, Marco, additional, Cattano, Davide, additional, Cauldwell, Charles B., additional, Cavallone, Laura, additional, Cereda, Maurizio, additional, Chalifoux, Thomas M., additional, Chan, Susan, additional, Cheek, Theodore G., additional, Chen, Alexander, additional, Cherry, Samuel A., additional, Cheung, Albert T., additional, Chien, Grace L., additional, Choi, Peter T., additional, Ciarallo, Christopher, additional, Cladis, Franklyn, additional, Clapcich, Anthony J., additional, Clark, Richard B., additional, Cohen, Mindy, additional, Cohen, Neal H., additional, Cohen, Robert I., additional, Cohn, Stephan J., additional, Conran, Aisling, additional, Cook, Richard I., additional, Coombs, Randall F., additional, Corda, David M., additional, Cormican, Daniel, additional, Cousin, Darren, additional, Cowell, Vincent S., additional, Cox, Lyndsey, additional, Craigo, Paula A., additional, Cross, Richard C., additional, Cucchiara, Roy F., additional, Daily, William H., additional, Dalal, Gaurang, additional, Dalal, Priti, additional, Danekas, Michael, additional, Darwish, Ahmed M., additional, Darwish, Ribal, additional, Daves, Suanne M., additional, Davis, Kathleen, additional, Davis, Peter J., additional, De Witt, Bracken J., additional, Delphin, Ellise, additional, Deshpande, Seema, additional, Desiderio, Dawn P., additional, Desvarieux, Tricia, additional, Diaz, Laura K., additional, Diez, Christian, additional, Dixit, Sanjay, additional, Dogra, Meenakshi, additional, Domino, Karen B., additional, Dorhauer, Kathryn, additional, Dorman, Todd, additional, Doussan, Don D., additional, Duke, James, additional, Duncan, Ann C., additional, Dupont, Frank W., additional, Dziewit, Andrew, additional, Easdown, L. Jane, additional, Easley, R. Blaine, additional, Ebert, Thomas J., additional, Eckmann, David M., additional, Egan, Talmage D., additional, Eisdorfer, Seth, additional, Elkassabany, Nabil M., additional, Ellender, Ryan P., additional, Emory, Logan S., additional, Espinosa, Monique, additional, Everett, Lucinda L., additional, Faraday, Nauder, additional, Fehr, James J., additional, Feld, James M., additional, Fenton, Lynn A., additional, Ferguson, Laura H., additional, Fiegel, Matthew, additional, Fields, Aaron M., additional, Finlayson, Gordon N., additional, Finley, Alan, additional, Fischer, Gregory W., additional, Fiskum, Gary, additional, Fitzpatrick, Molly, additional, Flatto, Russell, additional, Fleisher, Lee A., additional, Flower, Ronda, additional, Folgueras, Annette G., additional, Forte, Patrick J., additional, Foss, Joseph F., additional, Fox, Charles J., additional, Furman, William R., additional, Gaiser, Robert, additional, Gambling, David R., additional, Gardiner, Scott, additional, Garvey, Matthew L., additional, Gaupp, Abraham C., additional, Gayer, Steven, additional, Geiduschek, Jeremy M., additional, Gencorelli, Frank, additional, Gewirtz, Eric, additional, Ghani, Ghaleb A., additional, Gibbs, Charles P., additional, Gibson, Jeremy L., additional, Gilbert, Lori, additional, Gingrich, Kevin J., additional, Ginsburg, Gregory, additional, Giordano, Christopher, additional, Goepfert, Christine E., additional, Gomez, Hernando, additional, Gomez, Santiago, additional, Goodman, Alanna E., additional, Goodman, Stephanie R., additional, Gottlieb, Alexandru, additional, Gottlieb, Ori, additional, Gottschalk, Allan, additional, Goudra, Basavana Gouda, additional, Gould, Harry J., additional, Gravenstein, Nikolaus, additional, Graybill, Megan, additional, Greeley, William J., additional, Guffey, Patrick, additional, Haddadin, Ala Sami, additional, Hagen, John G., additional, Hakim, Karim Abdel, additional, Hall, Michael, additional, Halliday, N. James, additional, Hannallah, Raafat S., additional, Hansen, Jeremy, additional, Hanson, C. William, additional, Hantler, Charles B., additional, Harris, Andrew P., additional, Hastie, Jonathan, additional, Hawney, Henry A., additional, Heard, Stephen O., additional, Heavner, James E., additional, Hecker, James G., additional, Hein, Elizabeth A., additional, Heitmiller, Eugenie, additional, Helfaer, Mark, additional, Heller, Lori B., additional, Hemphill, Andrew, additional, Hendrickse, Adrian, additional, Hensley, Frederick A., additional, Herrick, Ian A., additional, Hester, Douglas, additional, Heyer, Eric J., additional, Higgins, Michael S., additional, Hines, Roberta, additional, Hogue, Charles W., additional, Holroyd, Kenneth J., additional, Holt, Natalie F., additional, Howell, Simon J., additional, Huda, Faisal, additional, Hude, Keith E., additional, Hughes, Hayden R., additional, Hunter, James M., additional, Hymel, Brad J., additional, Ibinson, James W., additional, Iles, Karen E., additional, Insoft, Robert M., additional, Isono, Shiroh, additional, Ivashkov, Yulia, additional, Jachna, Bozena R., additional, Jankowska, Anna, additional, Janosy, Norah, additional, Jayaraman, Arun L., additional, Jimenez, Nathalia, additional, Johnson, Judy G., additional, Jones, Lyndia, additional, Jooste, Edmund H., additional, Kain, Zeev N., additional, Kalangie, Maudy, additional, Kalarickal, Philip L., additional, Kamel, Ihab, additional, Kang, Mia, additional, Kangrga, Ivan, additional, Kapoor, Ravish, additional, Karl, Helen W., additional, Karsanac, Christopher, additional, Karthik, Swaminathan, additional, Katz, Jeffrey A., additional, Kaye, Alan, additional, Kaye, Adam M., additional, Kaynar, A. Murat, additional, Kenepp, Nancy B., additional, Kertai, Miklos D., additional, Keyes, Mary A., additional, Khan, Sarah, additional, Khoche, Swapnil, additional, Kim, David Y., additional, Kim, Jerry H., additional, King, Kimberly M., additional, Kirsch, Jeffrey, additional, Klopman, Matthew A., additional, Knight, Paul R., additional, Koblin, Donald D., additional, Kofke, W. Andrew, additional, Kopp, Vincent J., additional, Koveleskie, Joseph R., additional, Kowalczyk, Courtney, additional, Kozmenko, Valeriy V., additional, Krummen, Kaylyn, additional, Kudchadkar, Sapna R., additional, Kudrick, Nathan, additional, Kung, Adrienne, additional, Kurth, C. Dean, additional, Kyle, Robert, additional, LaFleur, J. Lance, additional, Lai, Jason G., additional, Lalwani, Kirk, additional, Lanier, William L., additional, Larson, Dawn M., additional, Layman, Richard M., additional, Lee, Chris C., additional, Lema, Mark J., additional, Lenox, W. Casey, additional, Leung, Jacqueline M., additional, Levitt, Roy C., additional, Levy, Jerrold H., additional, Lichtor, J. Lance, additional, Lin, Charles, additional, Lin, Sharon L., additional, Lindeman, Karen S., additional, Lirette, Lesley, additional, Litman, Ronald S., additional, Liu, Qianjin, additional, Liu, Renyu, additional, Liu, Wen-Shin, additional, Lockman, Justin, additional, Loftness, Stanley L., additional, London, Martin J., additional, Lumb, Philip D., additional, Lupa, M. Concetta, additional, Lynn, Anne Marie, additional, Mahendran, Devi, additional, Mako, Jeffrey, additional, Malhotra, Anuj, additional, Malhotra, Vinod, additional, Malinow, Andrew M., additional, Mandabach, Mark G., additional, Mangano, Dennis T., additional, Mansoor, Sobia, additional, Maranets, Inna, additional, Mark, Jonathan B., additional, Markovic, Sinisa, additional, Marsh, H. Michael, additional, Martin, Choendal, additional, Martin, Nicole D., additional, Martz, Douglas, additional, Matei, Veronica A., additional, Mathews, Letha, additional, Maxwell, Lynne G., additional, McArdle, Philip, additional, McCarren, John P., additional, McClain, Brenda C., additional, McClure, Brian, additional, McDade, William A., additional, McGoldrick, Kathryn E., additional, McGrath, Brian J., additional, McHugh, Gregory L., additional, McIlroy, David, additional, McKeown, Jason, additional, McLoughlin, Thomas M., additional, McRae, R. Yan, additional, Meadow, William L., additional, Menda, Sameer, additional, Merritt, William T., additional, Metro, David G., additional, Mets, Berend, additional, Mikhaeil, Hosni, additional, Miller, David W., additional, Miller, Jessica, additional, Minhaj, Mohammed, additional, Mirski, Marek A., additional, Mitter, Nanhi, additional, Mittnacht, Alexander J.C., additional, Modak, Raj K., additional, Moine, Pierre, additional, Monitto, Constance L., additional, Month, Richard C., additional, Moon, Richard E., additional, Moore, Laurel E., additional, Moore, Roger A., additional, Moore, Thomas A., additional, Morrison, Debra E., additional, Moss, Jonathan, additional, Moyers, John R., additional, Muir, Jesse J., additional, Munson-Young, Adam J., additional, Muravchick, Stanley, additional, Murkin, John M., additional, Nagele, Peter, additional, Nagi, Peter A., additional, Nahrwold, Daniel A., additional, Nahrwold, Michael L., additional, Naik, Madhavi, additional, Navaratnam, Manchula, additional, Nebbia, Stephan P., additional, Nelson, Priscilla, additional, Nguyen, Thai T., additional, Nguyen, Viet, additional, Nikolaidis, Stavroula, additional, Nisnevitch, Zoulfira, additional, Njoku, Dolores B., additional, Njoku, Mary J., additional, Norris, Edward J., additional, Nwokolo, Omonele O., additional, Nyhan, Daniel, additional, O'Byrne, William T., additional, Ochroch, Edward A., additional, Oken, Andrew, additional, Orgain, Nathan, additional, Oriol, Nancy E., additional, Orozco, Pedro, additional, Ostermeier, Andreas M., additional, Ovassapian, Andranik, additional, Ozcan, Mehmet S., additional, Padnos, Ira, additional, Pai, Sheela S., additional, Pal, Nirvik, additional, Palaniappan, Dhamodaran, additional, Palmer, Susan K., additional, Palte, Howard D., additional, Pan, Wei, additional, Panzer, Oliver, additional, Pappachan, Sibi, additional, Passannante, Anthony, additional, Patel, Dennis A., additional, Patel, Dilipkumar K., additional, Patel, Kirit M., additional, Patel, Samir, additional, Patel, Shalin, additional, Pathak, Sanup, additional, Patt, Minda L., additional, Pauldine, Ronald W., additional, Pawelek, Olga, additional, Pawelek, Tim, additional, Paydar, Kiarash, additional, Pearl, Ronald G., additional, Peeters-Asdourian, Christine, additional, Perela, Padmavathi R., additional, Petrovitch, Charise T., additional, Petrozza, Patricia H., additional, Phillips, Dennis, additional, Phillips, Mark C., additional, Piefer, Christine, additional, Pierre, Edgar J., additional, Pinson, S. William, additional, Pivalizza, Evan G., additional, Planinsic, Raymond M., additional, Poldermans, Don, additional, Pomerantz, Joel M., additional, Pope, Jason E., additional, Popescu, Wanda M., additional, Porche, Vivian H., additional, Porhomayon, Jahan, additional, Portnoy, Dmitry, additional, Postle, Corinne K., additional, Primeaux, Paul J., additional, Prough, Donald S., additional, Puskas, Ferenc, additional, Puyo, Carlos A., additional, Quiggle, Forrest, additional, Rabb, Mary, additional, Rae, Bronwyn R., additional, Rafique, Muhammad B., additional, Raiten, Jesse M., additional, Rajagopal, Arvind, additional, Rajagopal, Srinivasan, additional, Rajpal, Gaurav, additional, Ramamoorthy, Chandra, additional, Rampil, Ira J., additional, Ramsay, James G., additional, Ramsey, James A., additional, Rao, Vidya N., additional, Ratsiu, Joana, additional, Read, Selina, additional, Reddy, Ronjeet, additional, Reduque, Leila L., additional, Reich, David L., additional, Ricketts, Karene, additional, Ricks, Cameron, additional, Riedel, Bernhard, additional, Rimal, Jyotsna, additional, Rinehart, Joseph, additional, Riopelle, James M., additional, Rizza, Stacey A., additional, Robertson, Amy C., additional, Robinson, Stephen, additional, Rock, Peter, additional, Rodriguez-Blanco, Yillam F., additional, Roizen, Michael F., additional, Roke, Daniel M., additional, Romeo, Ryan, additional, Rosa, Joseph, additional, Rosen, David A., additional, Rosen, Kathleen, additional, Rosenbaum, Stanley H., additional, Rosenberg, Andrew D., additional, Rosenberg, Andrew L., additional, Rosenberg, Henry, additional, Rosenblatt, Meg A., additional, Roth, Steven, additional, Rothman, Brian, additional, Rountree, Justin L., additional, Rowan, Matthew J., additional, Rozner, Marc, additional, Rubin, Ryan, additional, Rupp, Stephen M., additional, Russell, W. John, additional, Russo, Thomas A., additional, Sabartinelli, Alecia L., additional, Sakai, Tetsuro, additional, Salinas, Orlando J., additional, Samm, Paul L., additional, Samuel, Jibin, additional, Sandven, Tor, additional, Sanford, Ted J., additional, Sappenfield, Joshua W., additional, Saravanan, Ponnusamy, additional, Sathishkumar, Subramanian, additional, Schlichter, R. Alexander, additional, Schnell, Eric, additional, Schreibman, David L., additional, Schubert, Armin, additional, Schulman, Peter, additional, Schultz, Todd A., additional, Schwartz, Alan Jay, additional, Schwartz, Jamie McElrath, additional, Schwartz, Jeffrey J., additional, Scott, Benjamin K., additional, Seltzer, Joseph L., additional, Seres, Tamas, additional, Sessler, Daniel I., additional, Sethna, Navil F., additional, Setty, Amar, additional, Shabaz, Paul W., additional, Shah, Pranav, additional, Shah, Saroj Mukesh, additional, Sharifpour, Milad, additional, Shay, Joanne, additional, Shepherd, Jay, additional, Shiffrin, Jeffrey S., additional, Shindell, Marina, additional, Siker, Daniel, additional, Silverman, Richard, additional, Simon, Brett A., additional, Singh, Nina, additional, Sinha, Ashish C., additional, Sladen, Robert N., additional, Slevin, Kieran A., additional, Sloan, Tod B., additional, Smith, Kathleen, additional, Smith, Timothy E., additional, Smoot, Victoria, additional, Snegovskikh, Denis, additional, Soifer, Betsy Ellen, additional, Solorzano, Molly, additional, Sonner, James M., additional, Sophocles, Aris, additional, Sparrow, James A., additional, Spiegel, Joan, additional, Spiess, Bruce D., additional, Sripada, Ramprasad, additional, Stead, Stanley W., additional, Stearns, Joshua D., additional, Stees, Kelly, additional, Steffey, Clinton, additional, Stemland, Christopher, additional, Stene, John, additional, Stephens, Christopher T., additional, Stierer, Tracey L., additional, Stokes, O. Jameson, additional, Stolp, Bryant W., additional, Stowe, David F., additional, Strickland, Ted, additional, Strom, Suzanne, additional, Sullivan, Erin A., additional, Sumler, Michele, additional, Sun, Dajin, additional, Sun, Lena, additional, Sung, Esther, additional, Swanson, Veronica C., additional, Szolnoki, Judit, additional, Talarico, Joe, additional, Tan, Gee Mei, additional, Tang, Darryl T., additional, Tarasi, Paul, additional, Tempelhoff, René, additional, Tetzlaff, John E., additional, Thorne, Alisa C., additional, Thung, Arlyne, additional, Tilak, Vasanti, additional, Tobin, Kate, additional, Tobin, Joseph R., additional, Tobin, Michael J., additional, Todd, R. David, additional, Tomlinson, Matthew, additional, Toung, Thomas J., additional, Tran, Lien B., additional, Tran, Minh Chau Joe, additional, Tremper, Kevin K., additional, Tsai, Sanyo, additional, Tseng, George S., additional, Tuman, Kenneth J., additional, Tung, Avery, additional, Tung, Cynthia, additional, Twersky, Rebecca, additional, Twite, Mark, additional, Ulatowski, John A., additional, Urban, Michael, additional, Vallejo, Manuel C., additional, Vannucci, Andrea, additional, Varon, Albert J., additional, Vasudevan, Anasuya, additional, Viswanathan, Susheela, additional, Vitin, Alexander A., additional, Voelckel, Wolfgang, additional, Walia, Ann, additional, Wall, Russell T., additional, Wallace, Terrence, additional, Wang, Shu-Ming, additional, Warltier, David C., additional, Waskell, Lucy, additional, Watkins, Scott, additional, Wedel, Denise, additional, Weiss, Stuart J., additional, Weissman, Charles, additional, Weitzel, Nathaen, additional, Weller, Gregory, additional, Whitney, Gina, additional, Whittington, Robert A., additional, Wilkerson, Danny, additional, Wilkes, Nancy C., additional, Williams, Michael, additional, Windsor, Jimmy, additional, Wittels, Bernard, additional, Wolff, Gregory A., additional, Wong, Andrew K., additional, Woods, Stacie N., additional, Wright, A.J., additional, Xie, Zheng, additional, Young, Christopher C., additional, Yuan, Ian, additional, Yudkowitz, Francine S., additional, Zaidan, James R., additional, Zanaboni, Paul, additional, Zapol, Warren M., additional, Zimmerman, Angela, additional, and Zwass, Maurice S., additional

Published
2011
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35. Predictors at Admission of Mechanical Ventilation and Death in an Observational Cohort of Adults Hospitalized With Coronavirus Disease 2019

Author

Jackson, Brendan R, primary, Gold, Jeremy A W, additional, Natarajan, Pavithra, additional, Rossow, John, additional, Neblett Fanfair, Robyn, additional, da Silva, Juliana, additional, Wong, Karen K, additional, Browning, Sean D, additional, Bamrah Morris, Sapna, additional, Rogers-Brown, Jessica, additional, Hernandez-Romieu, Alfonso C, additional, Szablewski, Christine M, additional, Oosmanally, Nadine, additional, Tobin-D’Angelo, Melissa, additional, Drenzek, Cherie, additional, Murphy, David J, additional, Hollberg, Julie, additional, Blum, James M, additional, Jansen, Robert, additional, Wright, David W, additional, Sewell, William M, additional, Owens, Jack D, additional, Lefkove, Benjamin, additional, Brown, Frank W, additional, Burton, Deron C, additional, Uyeki, Timothy M, additional, Bialek, Stephanie R, additional, Patel, Priti R, additional, and Bruce, Beau B, additional

Published
2020
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42. Predictors at Admission of Mechanical Ventilation and Death in an Observational Cohort of Adults Hospitalized With Coronavirus Disease 2019.

Author

Jackson, Brendan R, Gold, Jeremy A W, Natarajan, Pavithra, Rossow, John, Fanfair, Robyn Neblett, Silva, Juliana da, Wong, Karen K, Browning, Sean D, Morris, Sapna Bamrah, Rogers-Brown, Jessica, Hernandez-Romieu, Alfonso C, Szablewski, Christine M, Oosmanally, Nadine, Tobin-D'Angelo, Melissa, Drenzek, Cherie, Murphy, David J, Hollberg, Julie, Blum, James M, Jansen, Robert, and Wright, David W

Subjects
HOSPITALS, ANTIHYPERTENSIVE agents, COVID-19, SCIENTIFIC observation, CONFIDENCE intervals, VITAL signs, PATIENTS, PUBLIC health, RETROSPECTIVE studies, RANDOM forest algorithms, ARTIFICIAL respiration, HOSPITAL admission & discharge, HOSPITAL care, MEDICAL records, ODDS ratio, LONGITUDINAL method, ADULTS
Abstract

Background Coronavirus disease (COVID-19) can cause severe illness and death. Predictors of poor outcome collected on hospital admission may inform clinical and public health decisions. Methods We conducted a retrospective observational cohort investigation of 297 adults admitted to 8 academic and community hospitals in Georgia, United States, during March 2020. Using standardized medical record abstraction, we collected data on predictors including admission demographics, underlying medical conditions, outpatient antihypertensive medications, recorded symptoms, vital signs, radiographic findings, and laboratory values. We used random forest models to calculate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) for predictors of invasive mechanical ventilation (IMV) and death. Results Compared with age <45 years, ages 65–74 years and ≥75 years were predictors of IMV (aORs, 3.12 [95% CI, 1.47–6.60] and 2.79 [95% CI, 1.23–6.33], respectively) and the strongest predictors for death (aORs, 12.92 [95% CI, 3.26–51.25] and 18.06 [95% CI, 4.43–73.63], respectively). Comorbidities associated with death (aORs, 2.4–3.8; P  < .05) included end-stage renal disease, coronary artery disease, and neurologic disorders, but not pulmonary disease, immunocompromise, or hypertension. Prehospital use vs nonuse of angiotensin receptor blockers (aOR, 2.02 [95% CI, 1.03–3.96]) and dihydropyridine calcium channel blockers (aOR, 1.91 [95% CI, 1.03–3.55]) were associated with death. Conclusions After adjustment for patient and clinical characteristics, older age was the strongest predictor of death, exceeding comorbidities, abnormal vital signs, and laboratory test abnormalities. That coronary artery disease, but not chronic lung disease, was associated with death among hospitalized patients warrants further investigation, as do associations between certain antihypertensive medications and death. [ABSTRACT FROM AUTHOR]

Published
2021
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43. INC892792 Supplemental Material - Supplemental material for The effect of timing of initiation of renal replacement therapy on mortality: A retrospective case–control study

Author

Engoren, Milo, Maile, Michael D, Heung, Michael, Blum, James M, Blank, Ross, Napolitano, Lena M, Park, Pauline K, Raghavendran, Krishnan, Jewell, Elizabeth S, and Meldrum, Craig

Subjects
111708 Health and Community Services, FOS: Clinical medicine, Cardiology, 110323 Surgery, FOS: Health sciences, 110305 Emergency Medicine
Abstract

Supplemental material, INC892792 Supplemental Material for The effect of timing of initiation of renal replacement therapy on mortality: A retrospective case–control study by Milo Engoren, Michael D Maile, Michael Heung, James M Blum, Ross Blank, Lena M Napolitano, Pauline K Park, Krishnan Raghavendran, Elizabeth S Jewell and Craig Meldrum in Journal of the Intensive Care Society

Published
2019
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44. Stratification of morbidity and mortality outcome by preoperative risk factors in coronary artery bypass patients: a clinical severity score

Author

Higgins, Thomas L., Estafanous, Fawzy G., Loop, Floyd D., Beck, Gerald J., Blum, James M., and Paranandi, Lata

Subjects
Coronary artery bypass -- Complications, Risk factors (Health) -- Models, Mortality -- Risk factors
Abstract

A clinical model based on the severity of illness of patients undergoing a coronary artery bypass operation may be better at predicting an outcome of death or complications than methods currently used. Patients who were older or who had a previous emergency procedure, high blood creatinine levels, severe dysfunction of the left ventricle of the heart, insufficiency in the mitral valve, a hematocrit of 0.34, chronic lung disease or previous vascular surgery were more likely to die after coronary artery bypass surgery than were other patients. Individuals with diabetes, a high body weight (65 kg or more), aortic stenosis or cerebrovascular disease also had a higher risk of death than other individuals. Mathematical equations waiting the different factors were developed to classify patients undergoing coronary artery bypass in different risk categories. Patients were assigned risk-factor values of one to six points, and those with more points had a higher risk of death or complications such as infection, kidney failure or the need for artificial assistance.

Published
1992

47. A bibliometric search of citation classics in anesthesiology

Author

Tripathi Ravi S, Blum James M, Papadimos Thomas J, and Rosenberg Andrew L

Subjects
Anesthesiology, RD78.3-87.3
Abstract

Abstract Background Articles cited counts are catalogued and help identify landmark papers. This study provides a citation classics of anesthesiology literature using the framework of subspecialties to provide a review of well-developed areas of research in anesthesiology. Methods A comprehensive list of the most-cited articles in anesthesia was compiled using a bibliometric database and general search terms such as "anesthesia" as well as subspecialty-specific search terms. Queries were reviewed for relevance to anesthesiology practice, categorized by subspecialty, and ranked according to their citation counts. Results The database resulted in 2519 articles published between 1945 and 2008. The specialty areas most represented were chronic pain medicine (11%), pharmacology (9%), and pain sciences (9%). Conclusions This citations classic allows for advances in anesthesiology and its subspecialties to be highlighted as well to provide useful manuscripts to guide patient care, direct future research, and serve as sources for future academic pursuit.

Published
2011
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49. COVID-19 Clinical Phenotypes: Presentation and Temporal Progression of Disease in a Cohort of Hospitalized Adults in Georgia, United States.

Author

Silva, Juliana F da, Hernandez-Romieu, Alfonso C, Browning, Sean D, Bruce, Beau B, Natarajan, Pavithra, Morris, Sapna B, Gold, Jeremy A W, Fanfair, Robyn Neblett, Rogers-Brown, Jessica, Rossow, John, Szablewski, Christine M, Oosmanally, Nadine, D'Angelo, Melissa Tobin, Drenzek, Cherie, Murphy, David J, Hollberg, Julie, Blum, James M, Jansen, Robert, Wright, David W, and Sewell, William

Subjects
COVID-19, LEUKOCYTE count, DISEASE progression, LYMPHOCYTE count, MEDICAL care use
Abstract

Background The epidemiological features and outcomes of hospitalized adults with coronavirus disease 2019 (COVID-19) have been described; however, the temporal progression and medical complications of disease among hospitalized patients require further study. Detailed descriptions of the natural history of COVID-19 among hospitalized patients are paramount to optimize health care resource utilization, and the detection of different clinical phenotypes may allow tailored clinical management strategies. Methods This was a retrospective cohort study of 305 adult patients hospitalized with COVID-19 in 8 academic and community hospitals. Patient characteristics included demographics, comorbidities, medication use, medical complications, intensive care utilization, and longitudinal vital sign and laboratory test values. We examined laboratory and vital sign trends by mortality status and length of stay. To identify clinical phenotypes, we calculated Gower's dissimilarity matrix between each patient's clinical characteristics and clustered similar patients using the partitioning around medoids algorithm. Results One phenotype of 6 identified was characterized by high mortality (49%), older age, male sex, elevated inflammatory markers, high prevalence of cardiovascular disease, and shock. Patients with this severe phenotype had significantly elevated peak C-reactive protein creatinine, D-dimer, and white blood cell count and lower minimum lymphocyte count compared with other phenotypes (P  < .01, all comparisons). Conclusions Among a cohort of hospitalized adults, we identified a severe phenotype of COVID-19 based on the characteristics of its clinical course and poor prognosis. These findings need to be validated in other cohorts, as improved understanding of clinical phenotypes and risk factors for their development could help inform prognosis and tailored clinical management for COVID-19. [ABSTRACT FROM AUTHOR]

Published
2021
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