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Your search keyword '"Bloor, Adrian J.C."' showing total 12 results
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12 results on '"Bloor, Adrian J.C."'

3. Impact of positron emission tomography - computed tomography status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplantation

Author

Eyre, Toby A., primary, Barrington, Sally F., additional, Okosun, Jessica, additional, Abamba, Clementina, additional, Pearce, Rachel M., additional, Lee, Julia, additional, Carpenter, Ben, additional, Crawley, Charles R., additional, Bloor, Adrian J.C., additional, Gilleece, Maria, additional, Nicholson, Emma, additional, Shah, Nimish, additional, Orchard, Kim, additional, Malladi, Ram, additional, and Townsend, William M., additional

Published
2022
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4. Letermovir prophylaxis in T-cell–depleted transplants: breakthrough and rebound infections in the postmarketing setting

Author

Marzolini, Maria A.V., Mehra, Varun, Thomson, Kirsty J., Tholouli, Eleni, Bloor, Adrian J.C., Parker, Anne, Lovell, Richard, Orchard, Kim, Publicover, Amy, Nicholson, Emma, Snowden, John A., Byrne, Jennifer, Khan, Anjum, Gilleece, Maria H., Errico, Gerardo, Lozano, Sara, Hurst, Erin, Duncan, Nick, Pirrie, Jennifer, Crea, Philip, Carpenter, Ben, Pagliuca, Antonio, and Peggs, Karl S.

Published
2021
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7. Impact of Pretransplantation 18 F-Fluorodeoxyglucose-Positron Emission Tomography on Survival Outcomes after T Cell–Depleted Allogeneic Transplantation for Hodgkin Lymphoma

Author

Reyal, Yasmin, primary, Kayani, Irfan, additional, Bloor, Adrian J.C., additional, Fox, Christopher P., additional, Chakraverty, Ronjon, additional, Sjursen, Ann-Marie, additional, Fielding, Adele K., additional, Ben Taylor, Marcus, additional, Bishton, Mark J., additional, Morris, Emma C., additional, Thomson, Kirsty J., additional, Russell, Nigel, additional, Mackinnon, Stephen, additional, and Peggs, Karl S., additional

Published
2016
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8. T-Cell–Depleted Reduced-Intensity Transplantation Followed by Donor Leukocyte Infusions to Promote Graft-Versus-Lymphoma Activity Results in Excellent Long-Term Survival in Patients With Multiply Relapsed Follicular Lymphoma

Author

Thomson, Kirsty J., primary, Morris, Emma C., additional, Milligan, Don, additional, Parker, Anne N., additional, Hunter, Ann E., additional, Cook, Gordon, additional, Bloor, Adrian J.C., additional, Clark, Fiona, additional, Kazmi, Majid, additional, Linch, David C., additional, Chakraverty, Ronjon, additional, Peggs, Karl S., additional, and Mackinnon, Stephen, additional

Published
2010
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12. Rescue of the lethal scl−/−phenotype by the human SCLlocus

Author

Sinclair, Angus M., Bench, Anthony J., Bloor, Adrian J.C., Li, Juan, Göttgens, Berthold, Stanley, Maureen L., Miller, Jane, Piltz, Sandie, Hunter, Susie, Nacheva, Elisabeth P., Sanchez, Marı́a-José, and Green, Anthony R.

Abstract

The stem cell leukemia (SCL)gene encodes a basic helix-loop-helix transcription factor with a critical role in the development of both blood and endothelium. Loss-of-function studies have shown that SCL is essential for the formation of hematopoietic stem cells, for subsequent erythroid development and for yolk sac angiogenesis. SCL exhibits a highly conserved pattern of expression from mammals to teleost fish. Several murine SCLenhancers have been identified, each of which directs reporter gene expression in vivo to a subdomain of the normal SCL expression pattern. However, regulatory elements necessary for SCL expression in erythroid cells remain to be identified and the size of the chromosomal domain needed to support appropriate SCLtranscription is unknown. Here we demonstrate that a 130-kilobase (kb) yeast artificial chromosome (YAC) containing the human SCLlocus completely rescued the embryonic lethal phenotype ofscl−/−mice. Rescued YAC+scl−/−mice were born in appropriate Mendelian ratios, were healthy and fertile, and exhibited no detectable abnormality of yolk sac, fetal liver, or adult hematopoiesis. The human SCL protein can therefore substitute for its murine homologue. In addition, our results demonstrate that the human SCLYAC contains the chromosomal domain necessary to direct expression to the erythroid lineage and to all other tissues in which SCL performs a nonredundant essential function.

Published
2002
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