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• The hemovigilance system in Chongqing, China has been established, could provide representative regional data for the nation. • VVR showed a higher prevalence among young people, first-time, college students, and donors who donated in moving vehicles. • Among first-time whole blood donors, stratified analysis revealed seasonal and gender variation within a same age group. Vasovagal reactions (VVR) are the most common adverse reactions in blood donation. This study aimed to provide and analyze the data of the regional hemovigilance system in Chongqing, China from 2020 to 2022, report the prevalence and explore the risk factors of VVR. R software (version 4.2.3) was used for all statistical analyses. Frequency and composition rates were used to describe the data of total donation, as well as data on the different types of ADR. The Chi-square test was used to analyze risk factors for VVR and inter-group comparisons of VVR stratified by gender (female/male), age (18–22; 23–29; 30–39; 40–49; 50–60) and season(Spring (Mar.-May.); Summer (Jun.-Aug.); Autumn (sep.-Nov.); Winter (Dec.-Feb.)). The reported incidence rate of VVR was 8.69‰ during whole blood donations and 1.02‰ during platelet-apheresis donations.The stratified analysis revealed that female donors aged 18–22 years old and 30–39 years old were reported to have lower VVR rates than male donors, oppositely, higher in females in 50–60 years old. Statistically significant differences in the incidence rate of VVR were observed between winter and summer, and between winter and spring in 18–49 years old. No seasonal variation was found in 50–60 years old. The reported incidence rate of VVR related to blood donation was very low and varied from those calculated by other haemovigilance systems. The higher prevalence of VVR in young, first-time donors, college students, donating in mobile vehicles, males and in spring. Among first-time donors, the prevalence of VVR was higher in males than in females; and stratified analysis revealed there were seasonal variation and gender differences within a same age group. [ABSTRACT FROM AUTHOR]

Background Hypothesis/Objectives Animals Methods Results Conclusions and Clinical Importance Feline blood transfusion is required for the treatment of various illnesses in cats, and the safety of donor cats is vital. Donor adverse reactions can include cardiorespiratory, venepuncture‐related, and behavioral abnormalities.To describe a large number of feline blood donation events and document use of sedation and anxiolysis, record volume of blood collected and describe the frequency, type, and risk factors for, adverse reactions.The study included 7812 individual cats and 29 201 donation events at a blood banking center over 5 years.Retrospective analysis of donation event records with signalment, donation volume, sedation status, donation number, and adverse reactions (acute and caregiver reported) recorded. Risk factors for adverse reactions were examined by stratifying data according to groups exposed to relevant predictors and calculating odds ratios with 95% and 99% confidence intervals (CIs).Adverse reactions were uncommon (0.29%, 2.88/1000 donor events) and most commonly were cardiorespiratory (0.08%, 0.75/1000 donor events) or behavioral (0.06%, 0.62/1000 donor events). The only risk factor significantly associated with adverse reactions was conscious donation, with conscious donors 4.4 times more likely to have an adverse reaction (95% CI, 2.5‐7.9, P ≤ .0001).Feline blood donation is associated with a low rate of adverse reactions. Sedation should be considered to reduce adverse reactions, and the environment and interactions optimized to reduce donor stress. Caregiver education on care postdonation could reduce behavioral adverse reactions. [ABSTRACT FROM AUTHOR]

To compare the historical development of blood transfusion in Britain and a former British West Indian colony. International transfusion bodies recommend national coordination and exclusively voluntary non‐remunerated donation as essential pre‐requisites for blood safety. These ideals have been achieved in high‐income countries including Great Britain, the United States of America and Canada. However, most West Indian countries have fragmented, hospital‐based blood services that rely on family replacement and remunerated donors. Comparative historical analysis of blood transfusion service development in Great Britain and Trinidad and Tobago was undertaken to provide insight into their dichotomous development and inform policy decisions to bridge the gap between the two types of transfusion service. The British National Blood Transfusion service was based on voluntary non‐remunerated blood donation from its inception but achieved national coordination over 50 years that included a period of regional control during which incoordination contributed to a tainted blood scandal. Failure to establish community voluntary non‐remunerated donation in Trinidad and Tobago during the colonial period, before independence in 1962, allowed regionally‐controlled family replacement and remunerated blood donation to become entrenched then perpetuated by path dependence. A university‐led programme has recently used historically‐proven methods, drawing on the experiences of the British National Blood Transfusion Service, to establish a model for developing a voluntary non‐remunerated programme. The programme aims to avoid historical pitfalls during its national extension. Historical analysis provided information for introducing voluntary non‐remunerated blood donation and planning a nationally‐coordinated blood transfusion service. [ABSTRACT FROM AUTHOR]

Blood donation is a prosocial act driven by mechanisms related to altruism. While altruism plays a significant role, the processes behind blood donation behavior are complex, with altruism being just one factor. This research aimed to investigate the influence of altruism and meaning in life on the willingness to donate blood among Romanian undergraduate medical students during the COVID-19 pandemic. The sample consisted of 319 Romanian undergraduate medical students. Structural equation modeling (PLS-SEM) was used for statistical analysis. Our findings reveal that altruism did not significantly impact the willingness to donate blood directly; however, this relationship was mediated by meaning in life. In practice, blood donation could be increased through a more substantial connection between altruism and a sense of meaning in life, especially during health crises. Utilizing social marketing campaign messages that actively encourage altruism and connect it to a sense of meaning in life may increase blood donor recruitment and retention among undergraduate medical students. [ABSTRACT FROM AUTHOR]

Background: Currently in Australia, men are deferred from donating blood if they have had sex with another man within the past 3 months. However, a proposed gender‐neutral assessment (GNA) process will ask all donors questions about sex with new or multiple recent partners, with deferral based on responses to a question about anal sex. Understanding the acceptability of such questions among existing and potential blood donors is paramount for successful implementation of GNA. Study Design and Methods: We used data from a nationally representative survey to estimate the levels of comfort with the proposed GNA questions among the Australian population and subgroups, defined by self‐reported ethnicity and religion. Respondents were aged over 18 and living in Australia. Results were weighted to represent the population. Results: Most of the 5178 respondents described themselves as comfortable with answering questions about new partners (73.1%) or anal sex (64.0%) to donate blood. However, 2.2% and 4.5% indicated that questions about new sex partners and anal sex, respectively, would stop them from donating, and 4.4% and 7.7% respectively, said they were "completely uncomfortable." By religion, the least comfortable were Muslim or Eastern Orthodox respondents, and by country of birth, the least comfortable were those born in the Middle East, followed by those born in Southern Europe and Asia. Discussion: GNA appears to be broadly acceptable in the Australian context, but our findings suggest that key GNA questions are less acceptable in some population subgroups, indicating a need for targeted campaigns that consider cultural sensitivities. [ABSTRACT FROM AUTHOR]

Background: Many patients who require blood transfusion do not have timely access to safe blood and blood products. WHO states that at least 1% of the nation’s population should donate blood voluntarily to meet the basic requirements of blood. In India, there is a need for about 8 million units of blood every year. The need is predicted to increase by 5% every year. This study aimed to assess the knowledge, attitude and practices regarding blood donation among the general populace of a valley district in Manipur. Methods: A cross-sectional study was conducted among the general populace of a valley district in Manipur. Data was collected using a structured questionnaire through face-to-face interview and was summarized using descriptive statistics like mean, standard deviation and percentages. Association between variables of interest was analysed using chi square test. Conclusion: About one-fourth of the participants in this study had adequate knowledge (25.3%), favourable attitude (27.9%) and had donated blood at least once (27.6%). Males were more likely to have adequate knowledge regarding blood donation and to have donated blood compared to females. There was a significant association between educational qualification and religion with the level of knowledge, attitude and practice of blood donation. [ABSTRACT FROM AUTHOR]

Background: Many patients who require blood transfusion do not have timely access to safe blood and blood products. WHO states that at least 1% of the nation’s population should donate blood voluntarily to meet the basic requirements of blood. In India, there is a need for about 8 million units of blood every year. The need is predicted to increase by 5% every year. This study aimed to assess the knowledge, attitude and practices regarding blood donation among the general populace of a valley district in Manipur. Methods: A cross-sectional study was conducted among the general populace of a valley district in Manipur. Data was collected using a structured questionnaire through face-to-face interview and was summarized using descriptive statistics like mean, standard deviation and percentages. Association between variables of interest was analysed using chi square test. Conclusion: About one-fourth of the participants in this study had adequate knowledge (25.3%), favourable attitude (27.9%) and had donated blood at least once (27.6%). Males were more likely to have adequate knowledge regarding blood donation and to have donated blood compared to females. There was a significant association between educational qualification and religion with the level of knowledge, attitude and practice of blood donation. [ABSTRACT FROM AUTHOR]

Ensuring safe and effective blood transfusion is essential for improving healthcare and preventing the spread of blood-borne diseases worldwide. Medical students are a potential key resource for voluntary blood donation, particularly in medical college hospitals, which can help alleviate the shortage of blood products. Additionally, they have the potential to inspire a wider segment of the population to donate blood, thereby narrowing the gap between blood supply and demand. This study aims to evaluate the knowledge, perceptions, and practices related to voluntary blood donation among undergraduate medical students at Gulf Medical University in Ajman, United Arab Emirates, and to identify the factors associated with these aspects. A cross-sectional, institution-based study was conducted among undergraduate medical students at Gulf Medical University. Data were gathered through a self-administered structured questionnaire and analyzed using the Statistical Package for Social Sciences (SPSS) version 27. Knowledge, perceptions, and practices related to blood donation among 301 participants were assessed. The findings revealed no significant association between knowledge levels and demographics such as gender, marital status, residence, college, or academic year. While most participants were aware of blood donation procedures and benefits, actual donation practices were low, with 84.4% rarely donating blood. Key barriers included fear of needle pain and time constraints. Health professionals and social media were the primary sources of information, indicating the need for targeted educational interventions to improve blood donation rates. Students at Gulf Medical University are well-informed about blood donation, with many willing to donate. However, fears like needle pain and time constraints limit participation. Educational efforts could help overcome these barriers. [ABSTRACT FROM AUTHOR]

Background and Objectives: In Brazil, urban arboviruses, such as dengue virus (DENV), Zika virus (ZIKV) and chikungunya virus (CHIKV), constitute a major public health problem, and due to their endemicity and asymptomatic cases, they pose a potential threat to blood donations. Rio de Janeiro (RJ), Brazil, has been impacted by extensive DENV epidemics over the last 30 years and, after 2015, by CHIKV and ZIKV. Materials and Methods: Urban arboviruses DENV, ZIKV and CHIKV were investigated in blood donations (n = 778) at the State Institute of Hematology, HEMORIO (RJ) from 2019 to 2022 by serological and molecular methods. Results: An overall arbovirus exposure was observed in 26.1% of the blood donations. Anti‐DENV IgM was detected in 4.0% of samples and two donations were DENV NS1 positive. Positive anti‐CHIKV IgM was observed in 4.7% of the donations. Co‐detection of anti‐CHIKV IgM and anti‐DENV IgM was observed in 1.0% of donors, and CHIKV prevalence was 21.3%. All blood donations tested were negative for the DENV, ZIKV and CHIKV RNA. Conclusion: IgM seroprevalence to the arboviruses analyzed here is an indicator of recent infection in asymptomatic donors, showing that the population of blood donors can be a vehicle for new infections, especially during epidemic periods. [ABSTRACT FROM AUTHOR]

In healthy adults, parvovirus B19 (PVB19) typically causes mild symptoms but can lead to severe complications in immunosuppressed individuals or those with high red blood cell turnover. Infection can occur through respiratory transmission or via transfusion, necessitating the testing of blood donations in Germany. Between 2015 and April 2024, we screened 2 105 755 blood donations for PVB19 using polymerase chain reaction. Incidence rates were calculated for three periods: pre‐COVID‐19 (2015–2020), during the pandemic (2020–2023), and post‐COVID‐19 (2023–2024). A total of 242 PVB19‐positive donations were identified. In the first period, there were 101 positives out of 1 228 361 donations (incidence: 0.83/10 000). In the second period, four positives were found out of 621 222 donations (incidence: 0.06/10 000). In the third period, 137 positives were detected out of 235 088 donations (incidence: 5.35/10 000) with a striking increase of incidence between December 2023 and March 2024 (4.3–21.1/10 000 donations). Most people develop lifelong immunity after infection in childhood but the COVID‐19 pandemic interventions, like masks and distancing, correlate with a decline in PVB19 infections in donors indicating an impact of hygiene measures on PVB19 infection rates. [ABSTRACT FROM AUTHOR]

Many countries have modified their policies on banning or deferring blood donation by men who have sex with men (MSM) in light of ethical concerns and new evidence about transfusion risks. In Brazil, MSM were not eligible to donate blood unless they had been celibate for the previous 12 months. However, in May 2020, the Brazilian Federal Supreme Court overturned this restriction. Many authors have attempted to stress possible risks of transfusion-transmitted infection under various scenarios of changes in bans or restrictions on donations by MSM using mathematical models, but we consider that it is a difficult task due to the wide variety of sexual behaviors, attitudes, and practices. Among these factors, we highlight sex under the influence of illicit drugs, and the fact that people with an undetectable human immunodeficiency virus viral load have the potential to transmit should their blood be transfused. Despite these possible risks, we believe that some MSM can donate blood regardless of the time elapsed since their last sexual contact, especially because blood donations by MSM were occurring even when there were time-based deferral rules. Blood banks should always seek to use screening algorithms to identify high-risk sexual behaviors using gender-neutral criteria, and education about transfusion risks should be offered to healthcare workers and MSM.

ObjectiveTo analyze the epidemiological characteristics of hepatitis B virus (HBV) infection among blood donors in Hainan Province.MethodsHBV screening was conducted on 6 851 samples from voluntary blood donors in Hainan Province from January 2020 to January 2023. The samples were grouped according to donation frequency, method, age, gender, occupation, and education level, and risk factors related to HBV infection and genotypes were analyzed.ResultsThe HBV infection rate among first-time blood donors (3.59%) was higher than that among repeat donors (0.16%). Among first-time blood donors, the HBV infection rate in males (2.22%) was higher than in females (1.66%), and the infection rate increased with age (all P

Background: Cigarette smoking causes millions of deaths all around the world each year as it is one of the leading causes of cancer and cardiovascular diseases. Aims and Objectives: The study aimed to study the effect of cigarette smoking on coagulation profile, hematological parameters, and oxygen saturation in healthy blood donors. Materials and Methods: A case–control study was carried out at the Department of Pathology, Era’s Lucknow Medical College which is a tertiary care center, and took place between September 2018 and September 2020 (24 months). Results: Cigarette smoking has adverse effects on hematological parameters (red blood cell count, hemoglobin, hematocrit, mean corpuscular hemoglobin, red cell distribution width, and total leukocyte count) and coagulation profile (prothrombin time, activated partial thromboplastin time, and international normalized ratio). In our study, no adverse effects are seen on oxygen saturation though. Conclusion: Our study shows that hematological parameters and coagulation profile were altered in donors who were smokers and thus, it should be considered during blood donation. Although oxygen saturation was not adversely affected, this study strongly recommends the need for further studies to be done on this parameter of donated blood.

Abstract Background Hemotropic mycoplasmas, hemoplasmas, are epi‐erythrocytic parasitic bacteria that can be transmitted through blood transfusion. Objectives To study the prevalence of hemoplasma infection of potential feline blood donors and investigate the association between Hemoplasma spp. quantitative polymerase chain reaction (qPCR) positivity in blood units and selected variables. Animals Seven thousand five hundred seventy‐three blood units from 4121 privately‐owned potential donor cats. Methods Retrospective observational cross‐sectional study. The Banco Sangue Animal (BSA)—Animal Blood Bank medical database was reviewed for all feline donations performed in 2022 in Portugal, Spain, and Belgium. Baseline characteristics and results of blood‐borne pathogens screening tests were extracted from the medical records. Results Two hundred twelve of 4034 Portuguese donor cats and 2 of 70 Spanish donor cats tested positive for Hemoplasma spp. qPCR in 2022 leading to an overall estimated prevalence of 5.2% (95% CI: 4.5%‐5.9%) in potential blood donors. Using multivariable generalized estimation equation models, Hemoplasma spp. qPCR was more often positive among blood units issued from male cats (OR = 1.9, 95% CI: 1.4‐2.6, P

Abstract Background College and university students were an important population group of blood donors, especially in the current situation of tight blood supply. This study aimed to investigate the current status and determinants of blood donation among this population group in Wuhan using a structural equation model. Methods We conducted a cross-sectional study involving 12 colleges and universities in Wuhan, China, including 5168 students. Sociodemographic characteristics, health status, knowledge about blood donation, and attitude toward blood donation were treated as latent variables, with blood donation as the observed variable. Confirmatory factor analysis was conducted using the Mplus 8.0 statistical software application, followed by the establishment of a structural equation model to assess the relationships that exist between these variables. Results The overall blood donation rate among college and university students was 24.71%. The established model indicated that sociodemographic characteristics, health status, knowledge about blood donation, and attitude toward blood donation showed significant positive effects (0.135, 0.056, 0.321, and 0.389, respectively) on blood donation, among them, the direct effects were 0.076, -0.110, 0.143, and 0.389, respectively (P

Background: To determine the awareness and knowledge of blood donation and transfusion reactions among various departments in our tertiary care centre. Material and methods: The cross-sectional study, conducted at ACS Medical College and Hospital in Chennai from March to May 2024, focused on 20 departments. Researchers distributed a pre-tested, self-structured e-questionnaire to the participants, who submitted their responses via email to a designated account. Results: Out of the 20 departments surveyed, 64% were Faculty, 19% Postgraduate, and 17% were Interns. A significant majority, comprising 64% faculty, reported being aware of voluntary blood donation and transfusion reactions. However, despite the awareness and access to information, only a small fraction of the participants, knew about the right period of blood donation and transfusion reactions. Conclusion: This study infers that knowledge and awareness of blood donation and transfusion reactions were relatively higher among faculty in department of surgery, obstetrics and pathology and least among psychiatry, anatomy and forensic medicine. Based on these findings, the study recommends organising regular talks and interactive sessions as essential measures to bridge the gap in knowledge, identify and dispel misconceptions, and motivate individuals for regular discussions based on blood donation and transfusion reactions. These initiatives aim to enhance awareness, clarify any misunderstandings, and foster a proper knowledge about blood donation and transfusion reactions among the patients in time of need like mass destruction like accidents and natural calamities.

Abstract Background Despite word-of-mouth (WOM) and electronic WOM (eWOM) influencing people’s willingness to donate blood, no research has explored this behavior among blood service employees who are also donors. This underexplored segment is highly important, as they are generally committed to both the organization and the cause and are likely more informed on the topic of blood donation than the average donor. Methods This study comprised six online focus groups with 26 Australian Red Cross Lifeblood employees who are also donors. Questions covered a range of blood donation and WOM topics, including when they became blood donors, if they had engaged in WOM about blood donation, what they had talked about and with whom, and what were audience reactions. Thematic analysis was then used to explore how responses related to the employees’ motivations, opportunities, and abilities to engage in WOM and eWOM about blood donation. Results While most employee-donors saw alignment in their employee and donor roles, advocating for blood donation was not considered a necessary part of either role. Educating others about blood donation was a common goal of employee-donor WOM and eWOM, and almost all employees engaged in reactive WOM, triggered by events (e.g., recent donations) or questions about their work. Employee-donors in donor-facing roles (e.g., communications and collections staff) felt more aware of the importance of encouraging others to donate blood and were also more likely to be proactive in their WOM activity. Along with these perceived advantages of having a dual role, employee-donors also identified some disadvantages, such as unrealistic expertise expectations and negative audience responses that can be difficult to navigate. Conclusions Being an employee-donor is a double-edged sword. For example, increased opportunities to talk about blood donation and access to more information can be offset by having to respond to more challenging questions/comments and expectations, while appropriately representing their employer. More research is needed among those in employee-donor roles within the healthcare and/or non-profit sectors, to determine whether these are issues faced more broadly, and how those in dual roles can be most effectively supported to engage in positive WOM and eWOM.

Background and Objectives Materials and Methods Results Conclusion Facemasks represent an essential measure of prevention against the spread of infectious diseases; however, they lessen the ability to convey and understand emotions through facial expressions. In blood donation settings, facemask wearing could interfere with professionals' tasks, reduce the satisfaction of blood donors and affect their future blood donation behaviour. This preliminary cross‐sectional study explored the association of mandatory facemask wearing with the quality of the blood donation process at the end of the coronavirus 2019 (COVID‐19) pandemic.A sample of 615 voluntary unpaid Italian blood and plasma donors completed an online survey assessing their attitude towards facemask wearing, the perceived distress due to facemasks in the different steps of the donation process, self‐reported vasovagal reactions after donation and the intention to donate again.Nearly 24% of donors reported a worsened quality of the donation process due to facemask wearing, and 36% reported moderate to severe distress during the donation itself. Donors with a more negative attitude towards facemasks reported a worse donation experience, mainly related to the interactions and the communication with physicians and nurses, and a higher probability of experiencing vasovagal reactions at their last donation. No significant correlations were observed between negative facemask attitudes towards facemask wearing, distress or future intention to donate blood/plasma.Facemasks have worsened the quality of blood and plasma donations for one fourth of donors, confirming the interference with the quality of communications and relationships with healthcare professionals. [ABSTRACT FROM AUTHOR]

Background: Cigarette smoking causes millions of deaths all around the world each year as it is one of the leading causes of cancer and cardiovascular diseases. Aims and Objectives: The study aimed to study the effect of cigarette smoking on coagulation profile, hematological parameters, and oxygen saturation in healthy blood donors. Materials and Methods: A case- control study was carried out at the Department of Pathology, Era's Lucknow Medical College which is a tertiary care center, and took place between September 2018 and September 2020 (24 months). Results: Cigarette smoking has adverse effects on hematological parameters (red blood cell count, hemoglobin, hematocrit, mean corpuscular hemoglobin, red cell distribution width, and total leukocyte count) and coagulation profile (prothrombin time, activated partial thromboplastin time, and international normalized ratio). In our study, no adverse effects are seen on oxygen saturation though. Conclusion: Our study shows that hematological parameters and coagulation profile were altered in donors who were smokers and thus, it should be considered during blood donation. Although oxygen saturation was not adversely affected, this study strongly recommends the need for further studies to be done on this parameter of donated blood. [ABSTRACT FROM AUTHOR]

Human blood is one of the most valuable and irreplaceable goods in modern medicine. Although its necessity increases daily, one of the most significant challenges we have to overcome is a scarcity of willing blood donors. Volunteer motives and attitudes have been studied for decades, but it is now considered vital to grasp the many aspects that will increase the effectiveness of attracting new blood donors. This study focuses on the impact of emotional arousal produced by advertising messages, as well as the determining role of altruistic and egoistic incentives in deciding behavior. We also incorporated the element of personality to investigate how personality traits influence behavioral intention to donate blood. To this end, a quantitative non-experimental correlational 2 × 2 experimental design (positive vs. negative emotional appeal; altruistic vs. egoistic message) was implemented with the participation of 462 respondents who were shown a total of 12 advertisements (ads) promoting blood donation. The data were analyzed using structural equation modeling, with a focus on the direct impacts on donation intentions, the role of emotional arousals and attitude towards the ads as mediators and the moderating effect of the message. The empirical results of our hypotheses revealed that only Honesty–Humility had a strong direct impact on behavioral intention to donate, while Emotionality and Agreeableness did not have any direct effect. On the other hand, attitudes towards advertisements significantly and directly influenced positive and negative emotional arousals, respectively. Furthermore, if we consider these two variables alone, they can be found to exert a direct impact on BI. Mediation analysis showed that attitudes towards the advertisements and emotional arousals partially mediated the relation between Honesty-Humility and Behavioral Intention, thus confirming partial mediation. With respect to Emotionality and Agreeableness, mediation was found to be full since these factors only affected BI through a mediated path, which confirmed full mediation. Furthermore, the moderation analysis highlighted that the type of message (altruistic vs. egoistic) significantly moderated the relationship between both emotional arousals and BI. In particular, positive emotional arousal's influence is strengthened when it is aligned with altruistic messages, while negative emotional arousal's influence is weakened if it follows an altruistic message. These findings illustrate that using positive emotions will be more beneficial for increasing people's donation intentions than bringing negative ones, which implies that message framing has a hidden impact on donation decisions. [ABSTRACT FROM AUTHOR]

Background: Worldwide, insufficient blood donations cause blood shortages that jeopardize vital medical treatments for patients. Blood donation rates vary widely across countries, yet the determinants of this variation remain poorly understood. This study aims to illuminate the role of the institutional context in which blood donation is embedded by examining the link between country‐level blood donation rates and healthcare system quality. Study Design and Methods: The study employed a cross‐sectional design using data on blood donation rates from 171 countries from the 2021 WHO Global Status Report on Blood Safety and Availability and three healthcare quality indicators (i.e., Healthcare Access and Quality [HAQ] Index, life expectancy, and health expenditures). The pre‐registered hypotheses are tested using multiple linear regression. Robustness checks control for confounding factors. Results: HAQ Index and health expenditures are positively associated with blood donation rates, whereas life expectancy is not related to blood donation when controlling for confounds. Health expenditures display the most robust association with blood donations, even when controlling for confounding factors, and when comparing countries within the same continent. Conclusion: Higher healthcare system quality in terms of HAQ Index and higher healthcare expenditures are related to higher blood donation rates. The finding that healthcare expenditures are most consistently related to blood donation rates indicates that policymakers should consider prioritizing financial support for the healthcare system, including blood‐collecting institutions. More broadly, a better understanding of the role of contextual factors for blood donation may be needed to increase blood availability worldwide. [ABSTRACT FROM AUTHOR]

The Canadian health care system has been the site of a tense relationship between blood donation policies and African Canadians (read as Blacks). This article explores the basis of that strain, specifically the Canadian blood system's African Indefinite Deferral Policy and its relative underpinnings to, for example, the Creutzfeldt Jakob Disease Deferral Policy. Drawing from various data sources, the article demonstrates the subtle and diffuse aspects of the deferral policies in terms of the relationship between ethnicity and risk. The analysis provides important insights on the policies, based on the pejorative usage of ethnicity, especially its racial context, and related power dynamics, into understanding the lasting and plagued relationship that Blacks have had with the blood donation regime. Addressing questions around the institutional capacity of Canadian Blood Services and Héma Québec in dealing with minority ethnic groups is essential, particularly if the objective of blood donation policies is to address the health needs of Canada's increasingly diverse population. [ABSTRACT FROM AUTHOR]

• Approximately two-thirds of donors in Lebanon have adequate knowledge of blood donation; nevertheless, they exhibit reluctance to donate owing to apathy. • Merely 22.2% of donors are voluntary non-remunerated donors (VNRDs), with the remaining 77.8% being replacement donors. • The fragmented blood transfusion system, compounded by the continuous financial and socioeconomic turmoil, political inertia, and geopolitical disruptions, collectively impede the achievement of the World Health Organization's goal of achieving 100% VNRDs. • The active engagement of public authorities combined with the implementation of strategies gleaned from successful experiences in culturally akin neighboring countries, such as Morocco, are crucial for enhancing blood donation rates in Lebanon. The World Health Organization advocates for the achievement of 100% voluntary non-remunerated blood donation (VNRD) globally by the year 2020. However, until today, little was known in Lebanon regarding its actual rate or influencing factors, particularly donor motivations and behaviors. Therefore, the aim of this study was to assess the knowledge, attitudes, and practices of blood donors in Lebanon. The ultimate goals were to retain first-time donors, encourage them to become regular ones, and facilitate the transition from replacement donation to VNRD. A multi-centric cross-sectional study was carried across the five governorates in Lebanon. A self-administered and structured questionnaire was used in this survey. Results were presented in terms of odds ratios, with statistical significance defined at a P value of 0.05 and a 95% confidence interval. Additionally, a benchmarking analysis of the situation of blood donation in Lebanon was also conducted, identifying several areas for improvement. A total of 620 blood donors participated in this study, with 21.3% being first-time donors and 78.7% repeat donors. While the latter were primarily motivated by self-esteem, solidarity or returning a favor (89%, 77.9% and 78.1%), the main obstacle for becoming regular donors was a lack of initiative (34.6%). Female donors (9.9% of the total) exhibited better knowledge (OR = 2.20, p = 0.011) and were more inclined to donate voluntarily (OR = 1.52, p = 0.048). Conversely, male donors were more likely to be repeat donors, often through replacement donation (OR = 2.95, p = 0.001). There is a significant disparity between the low rate of voluntary donation in Lebanon (22.2%) and the relatively high proportion of donors with adequate knowledge of the donation process (60.5%). Therefore, urgent action by public authorities, based on the evidence based strategies outlined in this article, is crucial to enhancing the voluntary donation rate in Lebanon. [ABSTRACT FROM AUTHOR]

• Involvement of exogenous factors in the development of VVR remains unknown. • Meteorological conditions may play a role in blood donation-associated VVR onset. • Large diurnal temperature range may be a major risk factor. [ABSTRACT FROM AUTHOR]

In recognition of the impact of whole‐blood donation on body iron stores, there has been an increased focus assessing the efficacy of strategies to minimise the risk of iron deficiency (ID). Whilst donor behaviour is an important determinant of success, this literature is yet to be fully synthesised to help guide blood collection agencies when implementing these strategies into routine practice. This rapid review identifies strategies for management of low iron, how they have been communicated to donors, donor compliance with advice, donor use of external health services and their effect on donor retention. Web of Science, Medline, CINAHL and Wiley online library databases were searched from 2012 to November 2023, with 29 studies meeting inclusion criteria. Five iron management strategies were identified: oral iron supplementation (IS), education, dietary advice, lengthening inter‐donation interval and switching donation type. Most studies (n = 16) focused on IS, with only four reporting how they communicated this to donors. Donor use of IS was high in controlled research environments but has not been evaluated when implemented into routine practice. None of the four studies on dietary advice included findings on donor acceptability. The proportion of donors consulting their doctor about a low iron result or their risk of ID was found to be suboptimal. However, in general, the identified strategies and communications had a positive effect on donor retention. More evidence is needed on how to increase donor knowledge and awareness of donation‐related risk of ID as well as to identify how to effectively communicate strategies to donors to ensure optimal acceptability and use. [ABSTRACT FROM AUTHOR]

In 2019 the For The Assessment Of Individualised Risk (FAIR) project began a review of UK blood donor selection policy to determine if a more individualised approach to donor selection could be safely implemented. An evidence base was required to inform selection policy to move from a population to a more individual based policy, specifically what sexual behaviours/indicators should be considered as screening questions to maintain the safety of the blood supply. Eight sexual behaviours/indicators were reviewed: history of bacterial sexually transmitted infections (STIs), chemsex, number of recent partners, condom use, type of sex, sexual health service (SHS) attendance, new sexual partner and exclusivity. We conducted searches in multiple databases to identify literature looking at the association between these behaviours/indicators and HIV/STI acquisition risk. A scoring system to determine strength of evidence was devised and applied to papers that passed screening. Key studies were identified which achieved the maximum score and more in‐depth reviews were conducted for these. We identified 58 studies, including 17 key studies. Strong evidence was found linking a previous bacterial STI, chemsex and increasing numbers of sexual partners to acquisition risk. Condom use, type of sex and new partners were found to have some strength of evidence for this link. SHS attendance and exclusivity had minimal evidence. We recommended that the behaviours/indicators viewed as having strong or some strength of evidence should be considered as screening questions in a more individualised approach to donor selection criteria. [ABSTRACT FROM AUTHOR]

Background: College and university students were an important population group of blood donors, especially in the current situation of tight blood supply. This study aimed to investigate the current status and determinants of blood donation among this population group in Wuhan using a structural equation model. Methods: We conducted a cross-sectional study involving 12 colleges and universities in Wuhan, China, including 5168 students. Sociodemographic characteristics, health status, knowledge about blood donation, and attitude toward blood donation were treated as latent variables, with blood donation as the observed variable. Confirmatory factor analysis was conducted using the Mplus 8.0 statistical software application, followed by the establishment of a structural equation model to assess the relationships that exist between these variables. Results: The overall blood donation rate among college and university students was 24.71%. The established model indicated that sociodemographic characteristics, health status, knowledge about blood donation, and attitude toward blood donation showed significant positive effects (0.135, 0.056, 0.321, and 0.389, respectively) on blood donation, among them, the direct effects were 0.076, -0.110, 0.143, and 0.389, respectively (P < 0.01). Additionally, sociodemographic characteristics, health status, and knowledge about blood donation had indirectly affected blood donation through the mediating effect of attitude towards blood donation. Their effects on attitude towards blood donation were 0.099, 0.243, and 0.468, respectively. (P < 0.01). The model could explain explained 22.22% of the variance in blood donation behavior among college and university students in Wuhan. Conclusion: Blood donation among college and university students in Wuhan was associated with sociodemographic characteristics, health status, knowledge about blood donation, and attitude towards blood donation, with attitude being the primary influencing factor. Tailored recruitment strategies for blood donation among students should prioritize initiatives aimed at enhancing knowledge about blood donation and fostering positive attitudes toward it. [ABSTRACT FROM AUTHOR]

Simple Summary: Arboviruses, such as Ross River virus, Barmah Forest virus, and dengue virus, have the potential to pose a public health threat in Australia. Certain arboviruses pose significant concerns due to their potential impact on the safety and supply of blood transfusion products, necessitating a greater in-depth understanding of spatiotemporal patterns. This study analyzed the spatiotemporal distribution of eight arboviruses of public health significance in Australia from 2002 to 2017, using Geographic Information System mapping and space–time scan statistics. Key weather variables, including rainfall, temperature, and humidity, were found to influence arbovirus incidence rates and blood donation counts. The findings highlight regions at risk and offer insights for improving public health interventions. Arboviruses pose a significant global public health threat, with Ross River virus (RRV), Barmah Forest virus (BFV), and dengue virus (DENV) being among the most common and clinically significant in Australia. Some arboviruses, including those prevalent in Australia, have been reported to cause transfusion-transmitted infections. This study examined the spatiotemporal variation of these arboviruses and their potential impact on blood donation numbers across Australia. Using data from the Australian Department of Health on eight arboviruses from 2002 to 2017, we retrospectively assessed the distribution and clustering of incidence rates in space and time using Geographic Information System mapping and space–time scan statistics. Regression models were used to investigate how weather variables, their lag months, space, and time affect case and blood donation counts. The predictors' importance varied with the spatial scale of analysis. Key predictors were average rainfall, minimum temperature, daily temperature variation, and relative humidity. Blood donation number was significantly associated with the incidence rate of all viruses and its interaction with local transmission of DENV, overall. This study, the first to cover eight clinically relevant arboviruses at a fine geographical level in Australia, identifies regions at risk for transmission and provides valuable insights for public health intervention. [ABSTRACT FROM AUTHOR]

Background: Hemotropic mycoplasmas, hemoplasmas, are epi‐erythrocytic parasitic bacteria that can be transmitted through blood transfusion. Objectives: To study the prevalence of hemoplasma infection of potential feline blood donors and investigate the association between Hemoplasma spp. quantitative polymerase chain reaction (qPCR) positivity in blood units and selected variables. Animals: Seven thousand five hundred seventy‐three blood units from 4121 privately‐owned potential donor cats. Methods: Retrospective observational cross‐sectional study. The Banco Sangue Animal (BSA)—Animal Blood Bank medical database was reviewed for all feline donations performed in 2022 in Portugal, Spain, and Belgium. Baseline characteristics and results of blood‐borne pathogens screening tests were extracted from the medical records. Results: Two hundred twelve of 4034 Portuguese donor cats and 2 of 70 Spanish donor cats tested positive for Hemoplasma spp. qPCR in 2022 leading to an overall estimated prevalence of 5.2% (95% CI: 4.5%‐5.9%) in potential blood donors. Using multivariable generalized estimation equation models, Hemoplasma spp. qPCR was more often positive among blood units issued from male cats (OR = 1.9, 95% CI: 1.4‐2.6, P <.0001), units positive for FeLV (OR = 2.8, 95% CI: 1.4‐5.6, P =.0023), and units collected in winter months (OR = 2.5, 95% CI: 1.7‐3.6, P <.0001). Conclusions and Clinical Importance: This study underscores the importance of Hemoplasma spp. and other relevant blood‐borne pathogens screening at every donation. Implementing stringent screening protocols is crucial to mitigate the risk of hemoplasma transmission via blood transfusions, thereby safeguarding the health and welfare of cats receiving transfusions. [ABSTRACT FROM AUTHOR]

Background and Objectives: Maintaining stable blood supplies presents an increasing challenge for blood collection agencies (BCAs). Novel and multidisciplinary approaches and research have been called for to understand the mechanisms underlying the trends. The current body of sociological research on blood donation is a potentially valuable resource, but it is dispersed over different publications and theoretical frameworks. Materials and Methods: We conducted a scoping review of sociological research on voluntary, non‐remunerated blood donation to identify insights and practical applications for researchers and BCAs. Results: Four organizing themes were identified: donated blood, blood donors, organizations and blood service systems. Key challenges associated with the organization of voluntary blood donation exist at the institutional and systems levels, and they may not be readily resolved by interventions focussed solely on the individual donor level. We identified opportunities for organizations to build trust with donors and the public through communications and working with communities to promote inclusion in blood donation. Conclusion: The results support a multidisciplinary approach and research for BCAs to move forward and find novel ways to ensure safe, resilient blood service systems. [ABSTRACT FROM AUTHOR]

Background and Objectives: An increasing number of blood operators around the world, including those in Canada, have removed time‐based deferral periods for gay, bisexual and other men who have sex with men and replaced them with sexual behaviour‐based questions for all donors. While this marks a significant shift in screening approach, what remains unclear is how members of two‐spirit, lesbian, gay, bisexual, transgender and queer (2S/LGBTQ+) communities view blood operators' initiatives to be more inclusive. As such, this study was conducted to assess the awareness of donor screening changes and other initiatives among members of 2S/LGBTQ+ communities and to explore their recommendations for blood operators' work with these communities. Materials and Methods: Semi‐structured qualitative interviews (n = 15) were conducted with 2S/LGBTQ+ people across Canada. Data were analysed using open inductive coding methods. Results: Reported here are the key results on recommendations for blood operators. Three themes were identified from the data: (1) the need for increased communications with 2S/LGBTQ+ communities surrounding changes to donor policies and guidelines; (2) the need for trans‐inclusive policy and procedures; and (3) the need for culturally responsive and equity‐informed staff training at donor centres. Conclusion: Results suggest that blood operators should consider 2S/LGTBQ+ communities when developing blood and plasma donation policies, screening procedures and staff training. Increased consultation with these communities is desired, and further research specific to the experiences of transgender blood donors is needed. [ABSTRACT FROM AUTHOR]

Background and Objectives: The phenomenon of aggregates in apheresis‐derived platelet concentrates (APCs) has not yet been fully elucidated. Initially, visible aggregates (IVA) usually dissolve within 24 h after collection, but some persist till the end of the shelf life (persistent aggregates, PA). A study conducted at the Croatian Institute of Transfusion Medicine aimed to identify factors that influence the aggregate occurrence in APCs. Materials and Methods: We conducted a cross‐sectional study for the 2018–2022 period and collected data on APCs with IVA. We analysed APCs discarded due to PA separately for two apheresis technologies and compared them to the control group. Results: Significantly more donations were discarded in the IVA group compared with the control group and total number of discarded APCs. A total of 205 APCs were discarded due to PA (14.7% of IVA APCs and 1.27% of all APCs collected). Amicus APCs with PA had a significantly lower platelet count and mean platelet volume. They were obtained by procedures with less anticoagulant used. In contrast to Amicus APCs, Haemonetics APCs with PA had a significantly higher platelet count. None of the donor‐related factors examined was predictive of PA. Conclusion: APCs with IVA are more often discarded, not only due to aggregates, but also for impairment of other quality control parameters. Type of apheresis technology, being one of the most common risk factors for IVA, was not confirmed as the main risk factor for PA. There seem to be some donor‐related causal factors. [ABSTRACT FROM AUTHOR]

Background and Objectives: Blood donors are at risk of developing iron deficiency (ID) (ferritin <15 μg/L, World Health Organization definition). Blood services implement different strategies to mitigate this risk. Although in Finland risk group‐based iron supplementation is in place, no iron supplementation is provided in the Netherlands. We aim to describe differences in ferritin levels and ID prevalence in donor and general populations in these countries. Materials and Methods: Six cohorts, stratified based on sex, and for women age, in the Netherlands and Finland were used to evaluate differences in ferritin levels and ID between donor populations (Donor InSight‐III and FinDonor 10,000) and general populations (Prevention of Renal and Vascular End‐Stage Disease [PREVEND], FinRisk 1997 and Health 2000) and newly registered Dutch donors. Multivariable logistic regression was used to quantify associations of various explanatory factors with ID. Results: In total, 13,443 Dutch and 13,933 Finnish subjects were included. Donors, except for women aged ≤50 years old in Finland, had lower median ferritin levels compared with the general population and new donors. Dutch regular blood donors had higher or similar prevalence of ID as compared with the Dutch general population, including new donors. In contrast, Finnish donors showed similar prevalence of ID compared with the general population, except for a markedly lower prevalence in ≤50‐year‐old women who routinely receive iron supplements when donating. Conclusion: Iron status in blood donors differs from that in the general population. The Finnish blood service donor management policy, for example, iron supplementation for risk groups, seemingly protects young female blood donors from developing ID. [ABSTRACT FROM AUTHOR]

Background and Objectives: In the Netherlands, as of April 2018, the upper age limit for blood donation has been raised from 69 to 79 years, providing an opportunity to study older donors' perspectives regarding donating at older age. This study aims to explore whether older donors agree with the increase of the age limit, if they feel obliged to continue donating, to identify their motivators and barriers for donating blood and describe donation‐related experiences and complications. Materials and Methods: An online survey was distributed among Dutch blood donors aged 68–73 years. The survey contained questions regarding the increase of the upper age limit, motivations and barriers for donating, donation‐related experiences and obligatory feelings to continue donating. Results: Six hundred sixty donors (55%) were included in the analyses, including 38 stopped donors. Most donors (92%) agreed with the increase of the upper age limit. Approximately 63% of participating donors felt obliged to continue donating, especially women with high education. Donors indicated they felt healthy enough to keep donating (95%), and 72% thought it is good for their health to keep donating. Few donors reported that they found it hard to keep donating (5%) or indicated that they did not feel healthy enough to donate or thought it was not safe for them anymore (3.4%). Conclusion: Most of the older donors agree with the increase of the upper age limit for blood donation, report only few and minor donation‐related experiences or complications and are highly motivated to continue their donor career at an older age. [ABSTRACT FROM AUTHOR]

Background: Despite word-of-mouth (WOM) and electronic WOM (eWOM) influencing people's willingness to donate blood, no research has explored this behavior among blood service employees who are also donors. This underexplored segment is highly important, as they are generally committed to both the organization and the cause and are likely more informed on the topic of blood donation than the average donor. Methods: This study comprised six online focus groups with 26 Australian Red Cross Lifeblood employees who are also donors. Questions covered a range of blood donation and WOM topics, including when they became blood donors, if they had engaged in WOM about blood donation, what they had talked about and with whom, and what were audience reactions. Thematic analysis was then used to explore how responses related to the employees' motivations, opportunities, and abilities to engage in WOM and eWOM about blood donation. Results: While most employee-donors saw alignment in their employee and donor roles, advocating for blood donation was not considered a necessary part of either role. Educating others about blood donation was a common goal of employee-donor WOM and eWOM, and almost all employees engaged in reactive WOM, triggered by events (e.g., recent donations) or questions about their work. Employee-donors in donor-facing roles (e.g., communications and collections staff) felt more aware of the importance of encouraging others to donate blood and were also more likely to be proactive in their WOM activity. Along with these perceived advantages of having a dual role, employee-donors also identified some disadvantages, such as unrealistic expertise expectations and negative audience responses that can be difficult to navigate. Conclusions: Being an employee-donor is a double-edged sword. For example, increased opportunities to talk about blood donation and access to more information can be offset by having to respond to more challenging questions/comments and expectations, while appropriately representing their employer. More research is needed among those in employee-donor roles within the healthcare and/or non-profit sectors, to determine whether these are issues faced more broadly, and how those in dual roles can be most effectively supported to engage in positive WOM and eWOM. [ABSTRACT FROM AUTHOR]

Background and Objectives Evaluating the attitudes and beliefs of different classes of society is very important in attracting donors. This study aimed to evaluate the attitude of students of Alborz University of Medical Sciences regarding blood donation and investigate the obstacles in this field. Materials and Methods A descriptive cross-sectional study was conducted on 330 students of different fields of Alborz University of Medical Sciences in 2023. A questionnaire containing demographic questions and main research questions (12 questions to evaluate the causes of blood donation-7 questions to evaluate the reasons for not donating again in donors - 20 questions to evaluate the factors preventing blood donation in non-donors-12 questions about the general attitude to blood donation in donors and non-donors) were used to collect data. Data analysis was done with SPSS21 software and descriptive statistics. Results The average age was 22.85 ± 0.26 years and only 11.5% had history of donating blood. The most important motivating factors include altruistic causes (100%), feeling of responsibility (96.9%), moral and personal commitment (87.5%), participation in social activities (75%) and helping patients (71.9%). The most important reasons preventing blood donation are fear of dizziness and weakness (77.2% and 64.1%, respectively), lack of proper information (67%), fear of hand burning and hematoma (42.4%) and fear of anemia (47.8%). Conclusions Despite the low donation rate, most students had a positive attitude towards blood donation. In order to encourage students to donate blood, the necessary information should be provided through holding appropriate educational programs. [ABSTRACT FROM AUTHOR]

Background and Objectives: Accurate HIV incidence estimates among blood donors are necessary to assess the effectiveness of programs aimed at limiting transfusion‐transmitted HIV. We assessed the impact of undisclosed HIV status and antiretroviral (ARV) use on HIV recency and incidence estimates using increasingly comprehensive recent infection testing algorithms. Materials and Methods: Using 2017 donation data from first‐time and lapsed donors, we populated four HIV recency algorithms: (1) serology and limiting‐antigen avidity testing, (2) with individual donation nucleic amplification testing (ID‐NAT) added to Algorithm 1, (3) with viral load added to Algorithm 2 and (4) with ARV testing added to Algorithm 3. Algorithm‐specific mean durations of recent infection (MDRI) and false recency rates (FRR) were calculated and used to derive and compare incidence estimates. Results: Compared with Algorithm 4, progressive algorithms misclassified fewer donors as recent: Algorithm 1: 61 (12.1%); Algorithm 2: 14 (2.8%) and Algorithm 3: 3 (0.6%). Algorithm‐specific MDRI and FRR values resulted in marginally lower incidence estimates: Algorithm 1: 0.19% per annum (p.a.) (95% confidence interval [CI]: 0.13%–0.26%); Algorithm 2: 0.18% p.a. (95% CI: 0.13%–0.22%); Algorithm 3: 0.17% p.a. (95% CI: 0.13%–0.22%) and Algorithm 4: 0.17% p.a. (95% CI: 0.13%–0.21%). Conclusion: We confirmed significant misclassification of recent HIV cases when not including viral load and ARV testing. Context‐specific MDRI and FRR resulted in progressively lower incidence estimates but did not fully account for the context‐specific variability in incidence modelling. The inclusion of ARV testing, in addition to viral load and ID‐NAT testing, did not have a significant impact on incidence estimates. [ABSTRACT FROM AUTHOR]

Background and Objectives: Prior research has shown that temporary deferrals negatively influence donor return rates, but it remains unknown the extent to which these effects vary across reasons for deferral. We investigate whether deferrals differ in their degree of perceived stigmatization and, if so, how being deferred for stigmatizing (vs. non‐stigmatizing) reasons affects subsequent donation behaviour. Materials and Methods: We examined whether reasons for deferral vary on their perceived level of stigmatization through an online survey (n = 400). Furthermore, we used a dataset encompassing 25 years of donation records from the state‐run blood collection agency (BCA) from Rio de Janeiro, Brazil, to investigate how stigmatizing (vs. non‐stigmatizing) reasons for deferral affected return rates of 82,648 donors over a 60‐month follow‐up period. Results: Being deferred for sex‐ and drug‐related reasons was perceived as much more stigmatizing than other reasons for deferral (odds ratio = 3.14, 95% confidence interval [CI]: 2.33–4.25). Controlling for multiple observables, prospective donors were less likely to return to the BCA when deferred for stigmatizing (vs. non‐stigmatizing) reasons (adjusted hazard ratio = 0.87, 95% CI: 0.83–0.93). Conclusion: Donors perceive deferrals motivated by sex‐ and drug‐related reasons as particularly stigmatizing, which is negatively associated with donor return rates. BCAs may want to pay special attention when communicating stigmatizing reasons for deferral to prospective donors. [ABSTRACT FROM AUTHOR]

Blood donation heavily depends on voluntary involvement, but the problem of motivating and retaining potential blood donors remains. Understanding the personality traits of donors can assist in this case, bridging communication gaps and increasing participation and retention. To this end, an eye-tracking experiment was designed to examine the viewing behavior of 75 participants as they viewed various blood donation-related advertisements. The purpose of these stimuli was to elicit various types of emotions (positive/negative) and message framings (altruistic/egoistic) to investigate cognitive reactions that arise from donating blood using eye-tracking parameters such as the fixation duration, fixation count, saccade duration, and saccade amplitude. The results indicated significant differences among the eye-tracking metrics, suggesting that visual engagement varies considerably in response to different types of advertisements. The fixation duration also revealed substantial differences in emotions, logo types, and emotional arousal, suggesting that the nature of stimuli can affect how viewers disperse their attention. The saccade amplitude and saccade duration were also affected by the message framings, thus indicating their relevance to eye movement behavior. Generalised linear models (GLMs) showed significant influences of personality trait effects on eye-tracking metrics, including a negative association between honesty–humility and fixation duration and a positive link between openness and both the saccade duration and fixation count. These results indicate that personality traits can significantly impact visual attention processes. The present study broadens the current research frontier by employing machine learning techniques on the collected eye-tracking data to identify personality traits that can influence donation decisions and experiences. Participants' eye movements were analysed to categorize their dominant personality traits using hierarchical clustering, while machine learning algorithms, including Support Vector Machine (SVM), Random Forest, and k-Nearest Neighbours (KNN), were employed to predict personality traits. Among the models, SVM and KNN exhibited high accuracy (86.67%), while Random Forest scored considerably lower (66.67%). This investigation reveals that computational models can infer personality traits from eye movements, which shows great potential for psychological profiling and human–computer interaction. This study integrates psychology research and machine learning, paving the way for further studies on personality assessment by eye tracking. [ABSTRACT FROM AUTHOR]

Background: Improving global access to secure blood holds paramount importance for supporting medical interventions vital to saving lives. As students and professionals in the medical field are pivotal in informing and motivating the public to donate blood, this study investigated the awareness of blood donation requirements and protocols among undergraduate health sciences students at King Khalid University. Methods: A total of 106 students participated in the study. Google Forms was used to generate the survey and to collect data, and GraphPad Prism was used to visualize and analyze the data extracted from the form. Results: The study population was predominantly male (63.2% male vs. 36.8% female). Participants demonstrated a good understanding on questions pertaining to blood storage, transmitted infections, and the minimum weight requirement for donation. Divergent responses were observed regarding the optimal age for donation, minimal blood volume, fasting requirements, and the minimum interval between donations. Conclusions: The results of our study indicate a pressing need to enhance knowledge of blood donation among students in medical fields, particularly given the crucial role of health professionals in educating the public. Greater awareness will promote a greater frequency of donations and a wider dissemination of accurate information concerning blood donation protocols. [ABSTRACT FROM AUTHOR]

While blood is crucial for many surgeries and patient treatments worldwide, it cannot be produced artificially. Fulfilling the demand for blood products on average days is already a major challenge in countries like South Africa and Ghana. In these countries, less than 1 % of the population donates blood and most of the donations come from first-time donors who do not return. Sufficient new, first-time and even lapsed donors must be motivated to donate regularly. This study argues that blood donation behavior change support systems (BDBCSS) can be beneficially applied to support blood donor management in African countries. In this study, the design science research (DSR) approach is applied in order to derive generic design principles for BDBCSS and instantiate the design knowledge in prototypes for a blood donation app and a chatbot. The design principles were evaluated in a field study in South Africa. The results demonstrate the positive effects of BDBCSS on users' intentional and developmental blood donation behavior. This study contributes to research and practice by proposing a new conceptualization of blood donation information systems support and a nascent design theory for BDBCSS that builds on behavioral theories as well as related work on blood donation information systems. Thus, the study provides valuable implications for designing preventive health BCSS by stating three design principles for a concrete application context in healthcare. [ABSTRACT FROM AUTHOR]

Ensuring safe and effective blood transfusion is essential for improving healthcare and preventing the spread of blood-borne diseases worldwide. Medical students are a potential key resource for voluntary blood donation, particularly in medical college hospitals, which can help alleviate the shortage of blood products. Additionally, they have the potential to inspire a wider segment of the population to donate blood, thereby narrowing the gap between blood supply and demand. This study aims to evaluate the knowledge, perceptions, and practices related to voluntary blood donation among undergraduate medical students at Gulf Medical University in Ajman, United Arab Emirates, and to identify the factors associated with these aspects. A cross-sectional, institution-based study was conducted among undergraduate medical students at Gulf Medical University. Data were gathered through a self-administered structured questionnaire and analyzed using the Statistical Package for Social Sciences (SPSS) version 27. Knowledge, perceptions, and practices related to blood donation among 301 participants were assessed. The findings revealed no significant association between knowledge levels and demographics such as gender, marital status, residence, college, or academic year. While most participants were aware of blood donation procedures and benefits, actual donation practices were low, with 84.4% rarely donating blood. Key barriers included fear of needle pain and time constraints. Health professionals and social media were the primary sources of information, indicating the need for targeted educational interventions to improve blood donation rates. Students at Gulf Medical University are well-informed about blood donation, with many willing to donate. However, fears like needle pain and time constraints limit participation. Educational efforts could help overcome these barriers.

BACKGROUND: Blood donation is an essential global need far outweighs the available supply, rendering it a scarce and valuable resource. Within India, blood transfusion services hold significant importance and constitute a crucial aspect of the national health-care framework. Voluntary Non-Remunerated Blood Donation (VNRBD) is deemed the safest among the various ways of donating blood. The student population of educational institutions across the country, particularly those who are young and physically fit, represents one of the most promising sources of blood donations. The aim of the study was to evaluate the knowledge, attitudes, and donation practices of medical college students and motivate them to embrace voluntary blood donation as a regular habit. MATERIAL AND METHODS: The Department of Allied Health Science at Dr MGR Educational and Research Institute in Chennai, Tamil Nadu, India, conducted a questionnaire survey from March 2023 to October 2023. Two thousand and two hundred forty students were invited to participate, with 2331 ultimately willing to partake. The gathered data underwent analysis using the SPSS Statistics software, version 20, with a significance level fixed at a P = 5%. RESULTS: The study included 2331 participants, comprising 840 males (36%) and 1491 females (64%). The age range of the participants was between 17 and 25 years, with a mean age of 18.9 ± 1.3 years. Out of 2331 participants, the majority (66.7%) showed sufficient knowledge with 9 or more correct answers, while the rest (33.2%) showed below-average knowledge. CONCLUSION: The Tamil Nadu Health Professions Colleges possess the potential to make a noteworthy impact on the promotion of blood donation. According to a recent survey, students express a keen interest in donating blood if a camp is organized on the campus. By organizing awareness campaigns and conducting informative sessions, the colleges can inspire and motivate more students to donate blood, thereby playing a vital role in saving lives.