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3. A deprescribing programme aimed to optimise blood glucose-lowering medication in older people with type 2 diabetes mellitus, the OMED2-study: the study protocol for a randomised controlled trial

Author

Andriessen, Charlotte, Blom, Marieke T., van Hoek, Beryl A. C. E., de Boer, Anna W., Denig, Petra, de Wit, G. Ardine, Swart, Karin, de Rooij-Peek, Angela, van Marum, Rob J., Hugtenburg, Jacqueline G., Slottje, Pauline, van Raalte, Daniël, van Bloemendaal, Liselotte, Herings, Ron, Nijpels, Giel, Vos, Rimke C., and Elders, Petra J. M.

Published
2024
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6. Circulating metabolomic markers linking diabetic kidney disease and incident cardiovascular disease in type 2 diabetes: analyses from the Hong Kong Diabetes Biobank

Author

Jin, Qiao, Lau, Eric S. H., Luk, Andrea O., Tam, Claudia H. T., Ozaki, Risa, Lim, Cadmon K. P., Wu, Hongjiang, Chow, Elaine Y. K., Kong, Alice P. S., Lee, Heung Man, Fan, Baoqi, Ng, Alex C. W., Jiang, Guozhi, Lee, Ka Fai, Siu, Shing Chung, Hui, Grace, Tsang, Chiu Chi, Lau, Kam Piu, Leung, Jenny Y., Tsang, Man-wo, Cheung, Elaine Y. N., Kam, Grace, Lau, Ip Tim, Li, June K., Yeung, Vincent T. F., Lau, Emmy, Lo, Stanley, Fung, Samuel, Cheng, Yuk Lun, Chow, Chun Chung, Yu, Weichuan, Tsui, Stephen K. W., Tomlinson, Brian, Huang, Yu, Lan, Hui-yao, Szeto, Cheuk Chun, So, Wing Yee, Jenkins, Alicia J., Fung, Erik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Chan, Juliana C. N., and Ma, Ronald C. W.

Published
2024
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9. The association of obesogenic environments with weight status, blood pressure, and blood lipids: A cross-sectional pooled analysis across five cohorts

Author

T Schram, Miranda, Dagnelie, Pieter C., van Greevenbroek, Marleen MJ., Stehouwer, Coen DA., van der Kallen, Carla J., Meijer, Paul, Lam, Thao Minh, Vaartjes, Ilonca, Moll van Charante, Eric, Galenkamp, Henrike, Koster, Annemarie, van den Hurk, Katja, den Braver, Nicole R., Blom, Marieke T., de Jong, Trynke, Grobbee, Diederick E., Beulens, Joline WJ., and Lakerveld, Jeroen

Published
2024
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10. Adding ethnicity to cardiovascular risk prediction: External validation and model updating of SCORE2 using data from the HELIUS population cohort

Author

van Apeldoorn, Joshua A.N., Hageman, Steven H.J., Harskamp, Ralf E., Agyemang, Charles, van den Born, Bert-Jan H., van Dalen, Jan Willem, Galenkamp, Henrike, Hoevenaar-Blom, Marieke P., Richard, Edo, van Valkengoed, Irene G.M., Visseren, Frank L.J., Dorresteijn, Jannick A.N., and Moll van Charante, Eric P.

Published
2024
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13. Prevention of dementia using mobile phone applications (PRODEMOS): a multinational, randomised, controlled effectiveness–implementation trial

Author

Witvliet, Patrick, Hoitink, Mart, van de Groep, Bram, Liu, Hongmei, Ge, Siqi, He, Mingyue, Li, Cancan, Jian, Xuening, Jiang, Bin, Sun, Haixin, Ru, Xiaojuan, Sun, Dongling, Lian, Tenghong, Zhang, Weijiao, Zhang, Wenjing, Qi, Jing, Li, Jinghui, Guan, Huiying, Luo, Dongmei, Zhang, Weijia, Yue, Hao, Zheng, Zijing, Zeng, Qiang, Yang, Huangdai, Tang, Yanyan, Tao, Tianqi, Song, Yan, Meng, Xiaosheng, Zhu, Sirui, Jia, Dongmei, Li, Mo, Li, Wenjie, Mu, Haiyan, Jiang, Wenjing, Gao, Wenchao, Hu, Yueqing, Wang, Guohua, Xu, Xizhu, Zhang, Yichun, Li, Dong, Zhang, Xiaoyu, Guo, Xiuhua, Ye, Xiaoyan, Wei, Xi, Moll van Charante, Eric P, Hoevenaar-Blom, Marieke P, Song, Manshu, Andrieu, Sandrine, Barnes, Linda, Birck, Cindy, Brooks, Rachael, Coley, Nicola, Eggink, Esmé, Georges, Jean, Hafdi, Melanie, van Gool, Willem A, Handels, Ron, Hou, Haifeng, Lyu, Jihui, Niu, Yixuan, Song, Libin, Wang, Wenzhi, Wang, Youxin, Wimo, Anders, Yu, Yueyi, Zhang, Jinxia, Zhang, Wei, Brayne, Carol, Wang, Wei, and Richard, Edo

Published
2024
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15. A study protocol of external validation of eight COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting

Author

Zahra, Anum, Luijken, Kim, Abbink, Evertine J., van den Berg, Jesse M., Blom, Marieke T., Elders, Petra, Festen, Jan, Gussekloo, Jacobijn, Joling, Karlijn J., Melis, René, Mooijaart, Simon, Peters, Jeannette B., Polinder-Bos, Harmke A., van Raaij, Bas F. M., Smorenberg, Annemieke, la Roi-Teeuw, Hannah M., Moons, Karel G. M., and van Smeden, Maarten

Published
2023
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17. External validation of six COVID-19 prognostic models for predicting mortality risk in older populations in a hospital, primary care, and nursing home setting

Author

Zahra, Anum, van Smeden, Maarten, Abbink, Evertine J., van den Berg, Jesse M., Blom, Marieke T., van den Dries, Carline J., Gussekloo, Jacobijn, Wouters, Fenne, Joling, Karlijn J., Melis, René, Mooijaart, Simon P., Peters, Jeannette B., Polinder-Bos, Harmke A., van Raaij, Bas F.M., Appelman, Brent, la Roi-Teeuw, Hannah M., Moons, Karel G.M., and Luijken, Kim

Published
2024
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19. Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Author

Allesøe, Rosa Lundbye, Lundgaard, Agnete Troen, Hernández Medina, Ricardo, Aguayo-Orozco, Alejandro, Johansen, Joachim, Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, Lili, Biel, Jorge Hernansanz, Leal Rodríguez, Cristina, Brasas, Valentas, Webel, Henry, Benros, Michael Eriksen, Pedersen, Anders Gorm, Chmura, Piotr Jaroslaw, Jacobsen, Ulrik Plesner, Mari, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Hong, Mun-Gwan, Musholt, Petra B., De Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, E. Louise, Frost, Gary, Thomsen, Henrik, Hansen, Elizaveta, Hansen, Tue Haldor, Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, Jane, Hattersley, Andrew, McDonald, Timothy, Ridderstråle, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Hansen, Torben, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, McCarthy, Mark I., Pearson, Ewan, Banasik, Karina, Rasmussen, Simon, and Brunak, Søren

Published
2023
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20. The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action

Author

Marijon, Eloi, Narayanan, Kumar, Smith, Karen, Barra, Sérgio, Basso, Cristina, Blom, Marieke T, Crotti, Lia, D'Avila, Andre, Deo, Rajat, Dumas, Florence, Dzudie, Anastase, Farrugia, Audrey, Greeley, Kaitlyn, Hindricks, Gerhard, Hua, Wei, Ingles, Jodie, Iwami, Taku, Junttila, Juhani, Koster, Rudolph W, Le Polain De Waroux, Jean-Benoît, Olasveengen, Theresa M, Ong, Marcus E H, Papadakis, Michael, Sasson, Comilla, Shin, Sang Do, Tse, Hung-Fat, Tseng, Zian, Van Der Werf, Christian, Folke, Fredrik, Albert, Christine M, and Winkel, Bo Gregers

Published
2023
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24. Association of anthropometry and weight change with risk of dementia and its major subtypes: A meta‐analysis consisting 2.8 million adults with 57 294 cases of dementia

Author

Lee, Crystal ManYing, Woodward, Mark, Batty, G David, Beiser, Alexa S, Bell, Steven, Berr, Claudine, Bjertness, Espen, Chalmers, John, Clarke, Robert, Dartigues, Jean‐Francois, Davis‐Plourde, Kendra, Debette, Stéphanie, Di Angelantonio, Emanuele, Feart, Catherine, Frikke‐Schmidt, Ruth, Gregson, John, Haan, Mary N, Hassing, Linda B, Hayden, Kathleen M, Hoevenaar‐Blom, Marieke P, Kaprio, Jaakko, Kivimaki, Mika, Lappas, Georgios, Larson, Eric B, LeBlanc, Erin S, Lee, Anne, Lui, Li‐Yung, van Charante, Eric P Moll, Ninomiya, Toshiharu, Nordestgaard, Liv Tybjærg, Ohara, Tomoyuki, Ohkuma, Toshiaki, Palviainen, Teemu, Peres, Karine, Peters, Ruth, Qizilbash, Nawab, Richard, Edo, Rosengren, Annika, Seshadri, Sudha, Shipley, Martin, Singh‐Manoux, Archana, Strand, Bjorn Heine, Gool, Willem A, Vuoksimaa, Eero, Yaffe, Kristine, and Huxley, Rachel R

Subjects
Biomedical and Clinical Sciences, Nutrition and Dietetics, Health Sciences, Neurosciences, Dementia, Acquired Cognitive Impairment, Clinical Research, Nutrition, Neurodegenerative, Rare Diseases, Brain Disorders, Prevention, Aging, Obesity, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), 2.1 Biological and endogenous factors, Aetiology, Neurological, Cardiovascular, Adult, Aged, Anthropometry, Body Mass Index, Body Size, Body Weight, Dementia, Vascular, Female, Humans, Male, Middle Aged, Risk Factors, Thinness, Waist Circumference, Weight Gain, Weight Loss, Medical and Health Sciences, Psychology and Cognitive Sciences, Endocrinology & Metabolism, Biomedical and clinical sciences, Health sciences, Psychology
Abstract

Uncertainty exists regarding the relation of body size and weight change with dementia risk. As populations continue to age and the global obesity epidemic shows no sign of waning, reliable quantification of such associations is important. We examined the relationship of body mass index, waist circumference, and annual percent weight change with risk of dementia and its subtypes by pooling data from 19 prospective cohort studies and four clinical trials using meta-analysis. Compared with body mass index-defined lower-normal weight (18.5-22.4 kg/m2 ), the risk of all-cause dementia was higher among underweight individuals but lower among those with upper-normal (22.5-24.9 kg/m2 ) levels. Obesity was associated with higher risk in vascular dementia. Similarly, relative to the lowest fifth of waist circumference, those in the highest fifth had nonsignificant higher vascular dementia risk. Weight loss was associated with higher all-cause dementia risk relative to weight maintenance. Weight gain was weakly associated with higher vascular dementia risk. The relationship between body size, weight change, and dementia is complex and exhibits non-linear associations depending on dementia subtype under scrutiny. Weight loss was associated with an elevated risk most likely due to reverse causality and/or pathophysiological changes in the brain, although the latter remains speculative.

Published
2020

27. Diagnostic Accuracy of the Telephone Interview for Cognitive Status for the Detection of Dementia in Primary Care

Author

Abdulrahman, Herrer, Jansen, Eva, Hoevenaar-Blom, Marieke, van Dalen, Jan Willem, van Wanrooij, Lennard L., van Bussel, Emma, van Gool, Willem A., Richard, Edo, and van Charante, Eric P. Moll

Subjects
Dementia -- Diagnosis, Telemedicine -- Usage, Primary health care -- Methods, Health, Science and technology
Abstract

PURPOSE Cognitive diagnostic work-up in primary care is not always physically feasible, owing to chronic disabilities and/or travel restrictions. The identification of dementia might be facilitated with diagnostic instruments that are time efficient and easy to perform, as well as useful in the remote setting. We assessed whether the Telephone Interview for Cognitive Status (TICS) might be a simple and accurate alternative for remote diagnostic cognitive screening in primary care. METHODS We administered the TICS (range, 0-41) for 810 of 1,473 older people aged 84.5 (SD, 2.4) years. We scrutinized electronic health records for participants with TICS scores [less than or equal to] 30 and for a random sample of participants with TICS scores >30 for a dementia diagnosis using all data from the Prevention of Dementia by Intensive Vascular Care (preDIVA) trial for 8-12 years of follow-up. We used multiple imputation to correct for verification bias. RESULTS Of the 810 participants, 155 (19.1%) had a TICS score [less than or equal to] 30, and 655 (80.9%) had a TICS score >30. Electronic health records yielded 8.4% (13/154) dementia diagnoses for participants with TICS [less than or equal to] 30 vs none with TICS >30. Multiple imputation for TICS >30 yielded a median of 7/655 (1.1%; interquartile range, 5-8) estimated dementia cases. After multiple imputation, the optimal cutoff score was [less than or equal to] 29, with mean sensitivity 65.4%, specificity 87.8%, positive predictive value 11.9%, negative predictive value 99.0%, and area under the curve 77.4% (95% CI, 56.3%-90.0%). CONCLUSIONS In the present older population, the TICS performed well as a diagnostic screening instrument for excluding dementia and might be particularly useful when face-toface diagnostic screening is not feasible in family practice or research settings. The potential reach to large numbers of people at low cost could contribute to more efficient medical management in primary care. Ann Fam Med 2022;20:130-136. https://doi.org/10.1370/afm.2768, INTRODUCTION In recent decades, increasing emphasis has been placed on early intervention in the care and treatment of persons with dementia to help provide more efficient medical management and advanced [...]

Published
2022
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29. Harmonization of the definition of sudden cardiac death in longitudinal cohorts of the European Sudden Cardiac Arrest network – towards Prevention, Education, and New Effective Treatments (ESCAPE-NET) consortium

Author

Warming, Peder Emil, Ågesen, Frederik Nybye, Lynge, Thomas Hadberg, Jabbari, Reza, Smits, Robin L.A., van Valkengoed, Irene G.M., Welten, Sabrina J.G.C., van der Heijden, Amber A., Elders, Petra J., Blom, Marieke T., Jouven, Xavier, Schwartz, Peter J., Albert, Christine M., Beulens, Joline W., Rutters, Femke, Tan, Hanno L., Empana, Jean-Philippe, and Tfelt-Hansen, Jacob

Published
2022
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31. Author Correction: Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Author

Allesøe, Rosa Lundbye, Lundgaard, Agnete Troen, Hernández Medina, Ricardo, Aguayo-Orozco, Alejandro, Johansen, Joachim, Nissen, Jakob Nybo, Brorsson, Caroline, Mazzoni, Gianluca, Niu, Lili, Biel, Jorge Hernansanz, Leal Rodríguez, Cristina, Brasas, Valentas, Webel, Henry, Benros, Michael Eriksen, Pedersen, Anders Gorm, Chmura, Piotr Jaroslaw, Jacobsen, Ulrik Plesner, Mari, Andrea, Koivula, Robert, Mahajan, Anubha, Vinuela, Ana, Tajes, Juan Fernandez, Sharma, Sapna, Haid, Mark, Hong, Mun-Gwan, Musholt, Petra B., De Masi, Federico, Vogt, Josef, Pedersen, Helle Krogh, Gudmundsdottir, Valborg, Jones, Angus, Kennedy, Gwen, Bell, Jimmy, Thomas, E. Louise, Frost, Gary, Thomsen, Henrik, Hansen, Elizaveta, Hansen, Tue Haldor, Vestergaard, Henrik, Muilwijk, Mirthe, Blom, Marieke T., ‘t Hart, Leen M., Pattou, Francois, Raverdy, Violeta, Brage, Soren, Kokkola, Tarja, Heggie, Alison, McEvoy, Donna, Mourby, Miranda, Kaye, Jane, Hattersley, Andrew, McDonald, Timothy, Ridderstråle, Martin, Walker, Mark, Forgie, Ian, Giordano, Giuseppe N., Pavo, Imre, Ruetten, Hartmut, Pedersen, Oluf, Hansen, Torben, Dermitzakis, Emmanouil, Franks, Paul W., Schwenk, Jochen M., Adamski, Jerzy, McCarthy, Mark I., Pearson, Ewan, Banasik, Karina, Rasmussen, Simon, and Brunak, Søren

Published
2023
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32. A comprehensive evaluation of the genetic architecture of sudden cardiac arrest

Author

Ashar, Foram N, Mitchell, Rebecca N, Albert, Christine M, Newton-Cheh, Christopher, Brody, Jennifer A, Müller-Nurasyid, Martina, Moes, Anna, Meitinger, Thomas, Mak, Angel, Huikuri, Heikki, Junttila, M Juhani, Goyette, Philippe, Pulit, Sara L, Pazoki, Raha, Tanck, Michael W, Blom, Marieke T, Zhao, XiaoQing, Havulinna, Aki S, Jabbari, Reza, Glinge, Charlotte, Tragante, Vinicius, Escher, Stefan A, Chakravarti, Aravinda, Ehret, Georg, Coresh, Josef, Li, Man, Prineas, Ronald J, Franco, Oscar H, Kwok, Pui-Yan, Lumley, Thomas, Dumas, Florence, McKnight, Barbara, Rotter, Jerome I, Lemaitre, Rozenn N, Heckbert, Susan R, O’Donnell, Christopher J, Hwang, Shih-Jen, Tardif, Jean-Claude, VanDenburgh, Martin, Uitterlinden, André G, Hofman, Albert, Stricker, Bruno HC, de Bakker, Paul IW, Franks, Paul W, Jansson, Jan-Hakan, Asselbergs, Folkert W, Halushka, Marc K, Maleszewski, Joseph J, Tfelt-Hansen, Jacob, Engstrøm, Thomas, Salomaa, Veikko, Virmani, Renu, Kolodgie, Frank, Wilde, Arthur AM, Tan, Hanno L, Bezzina, Connie R, Eijgelsheim, Mark, Rioux, John D, Jouven, Xavier, Kääb, Stefan, Psaty, Bruce M, Siscovick, David S, Arking, Dan E, and Sotoodehnia, Nona

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Prevention, Heart Disease, Human Genome, Genetics, Clinical Research, Heart Disease - Coronary Heart Disease, Cardiovascular, 2.1 Biological and endogenous factors, Aetiology, Good Health and Well Being, Arrhythmias, Cardiac, Body Mass Index, Coronary Artery Disease, Death, Sudden, Cardiac, Female, Genome-Wide Association Study, Heart Conduction System, Humans, Male, Mendelian Randomization Analysis, Polymorphism, Single Nucleotide, Risk Assessment, Risk Factors, Sex Factors, Sudden cardiac arrest, Genome-wide association study, Mendelian randomization, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

AimsSudden cardiac arrest (SCA) accounts for 10% of adult mortality in Western populations. We aim to identify potential loci associated with SCA and to identify risk factors causally associated with SCA.Methods and resultsWe carried out a large genome-wide association study (GWAS) for SCA (n = 3939 cases, 25 989 non-cases) to examine common variation genome-wide and in candidate arrhythmia genes. We also exploited Mendelian randomization (MR) methods using cross-trait multi-variant genetic risk score associations (GRSA) to assess causal relationships of 18 risk factors with SCA. No variants were associated with SCA at genome-wide significance, nor were common variants in candidate arrhythmia genes associated with SCA at nominal significance. Using cross-trait GRSA, we established genetic correlation between SCA and (i) coronary artery disease (CAD) and traditional CAD risk factors (blood pressure, lipids, and diabetes), (ii) height and BMI, and (iii) electrical instability traits (QT and atrial fibrillation), suggesting aetiologic roles for these traits in SCA risk.ConclusionsOur findings show that a comprehensive approach to the genetic architecture of SCA can shed light on the determinants of a complex life-threatening condition with multiple influencing factors in the general population. The results of this genetic analysis, both positive and negative findings, have implications for evaluating the genetic architecture of patients with a family history of SCA, and for efforts to prevent SCA in high-risk populations and the general community.

Published
2018

34. Genomics Research of Lifetime Depression in the Netherlands: The BIObanks Netherlands Internet Collaboration (BIONIC) Project

Author

Huider, Floris, primary, Milaneschi, Yuri, additional, Hottenga, Jouke-Jan, additional, Bot, Mariska, additional, Rietman, M. Liset, additional, Kok, Almar A.L., additional, Galesloot, Tessel E., additional, ‘t Hart, Leen M., additional, Rutters, Femke, additional, Blom, Marieke T., additional, Rhebergen, Didi, additional, Visser, Marjolein, additional, Brouwer, Ingeborg, additional, Feskens, Edith, additional, Hartman, Catharina A., additional, Oldehinkel, Albertine J., additional, de Geus, Eco J.C., additional, Kiemeney, Lambertus A., additional, Huisman, Martijn, additional, Picavet, H. Susan J., additional, Verschuren, W.M. Monique, additional, van Loo, Hanna M., additional, Penninx, Brenda W.J.H., additional, and Boomsma, Dorret I., additional

Published
2024
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37. The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study

Author

Eriksen, Rebeca, White, Margaret C, Dawed, Adem Y, Perez, Isabel Garcia, Posma, Joram M, Haid, Mark, Sharma, Sapna, Prehn, Cornelia, Thomas, E Louise, Koivula, Robert W, Bizzotto, Roberto, Mari, Andrea, Giordano, Giuseppe N, Pavo, Imre, Schwenk, Jochen M, De Masi, Federico, Tsirigos, Konstantinos D, Brunak, Søren, Viñuela, Ana, Mahajan, Anubha, McDonald, Timothy J, Kokkola, Tarja, Rutters, Femke, Beulens, Joline, Muilwijk, Mirthe, Blom, Marieke, Elders, Petra, Hansen, Tue H, Fernandez-Tajes, Juan, Jones, Angus, Jennison, Chris, Walker, Mark, McCarthy, Mark I, Pedersen, Oluf, Ruetten, Hartmut, Forgie, Ian, Holst, Jens J, Thomsen, Henrik S, Ridderstråle, Martin, Bell, Jimmy D, Adamski, Jerzy, Franks, Paul W, Hansen, Torben, Holmes, Elaine, Frost, Gary, and Pearson, Ewan R

Published
2024
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39. Prevention of dementia using mobile phone applications (PRODEMOS): a multinational, randomised, controlled effectiveness-implementation trial

Author

Moll van Charante, Eric P., Hoevenaar-Blom, Marieke P., Song, Manshu, Andrieu, S., Barnes, L., Birck, C., Wang, Wei, Richard, E., Moll van Charante, Eric P., Hoevenaar-Blom, Marieke P., Song, Manshu, Andrieu, S., Barnes, L., Birck, C., Wang, Wei, and Richard, E.

Abstract

Contains fulltext : 307466.pdf (Publisher’s version ) (Open Access)

Published
2024

40. Type 2 Diabetes, the Epidemic: Trends in Prevalence and Incidence, 2004-2020

Author

Overbeek,Jetty, Nijpels,Giel, Swart,Karin, Blom,Marieke, Elders,Petra, Herings,Ron, Overbeek,Jetty, Nijpels,Giel, Swart,Karin, Blom,Marieke, Elders,Petra, and Herings,Ron

Abstract

Jetty A Overbeek,1,2 Giel Nijpels,2 Karin MA Swart,1,2 Marieke T Blom,2,3 Petra JM Elders,2,3 Ron MC Herings1,4 1PHARMO Institute for Drug Outcomes Research, Utrecht, Netherlands; 2Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of General Practice, Amsterdam, Netherlands; 3Amsterdam Public Health, Health Behaviors & Chronic Diseases, Amsterdam, Netherlands; 4Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Epidemiology and Data Science, Amsterdam, NetherlandsCorrespondence: Jetty A Overbeek, Email jetty.overbeek@pharmo.nlAims/Hypothesis: Only a few studies reported the incidence of type 2 diabetes (T2D). Understanding recent trends in diabetes is vital for planning future diabetes care. This study updated national trends in the prevalence and incidence of type 2 diabetes (T2D) in the Netherlands from 2004– 2020.Methods: The DIAbetes, MANagement and Treatment (DIAMANT) cohort was used. A cross-sectional design with yearly measurements for the study period was used. The prevalence was calculated by dividing the total number of people with T2D by the total number of all residents. The incidence was calculated by dividing new cases of T2D by the resident population at risk during the calendar year of interest.Results: Among men, the prevalence of T2D in the Netherlands increased from 2.3% in 2004 to 6.3% in 2020. Women’s prevalence increased from 2.3% in 2004 to 5.3% in 2020. During 2005– 2009, the incidence rate for both men and women was relatively stable Between 2010 and 2020, the incidence rate fell about 1.5 per 1000 in both men and women.Conclusion: From 2004– 2020, the prevalence of T2D in the Netherlands more than doubled, with a decreasing incidence from 2010 onwards.Plain Language Summary: Research in contextWhat is already known about this subject?Many studies have reported the increasing prevalence of type 2 diabetes (T2D). However, only a few studies reported the incidence.In a recent systematic review of all

Published
2024

43. Using routine primary care data to assess Sudden Cardiac Arrest risk in people with type 2 diabetes: a proof-of-concept case-control study

Author

Harms, Peter P., primary, van Dongen, Laura H, additional, Oosterbaan, Nicky I.C., additional, Bennis, Frank C., additional, Beulens, Joline WJ, additional, Swart, Karin M.A., additional, Hoogendoorn, Mark, additional, Tan, Hanno L., additional, Elders, Petra P.J.M., additional, and Blom, Marieke T., additional

Published
2024
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47. Healthy ageing through internet counselling in the elderly (HATICE): a multinational, randomised controlled trial

Author

Richard, Edo, Moll van Charante, Eric P, Hoevenaar-Blom, Marieke P, Coley, Nicola, Barbera, Mariagnese, van der Groep, Abraham, Meiller, Yannick, Mangialasche, Francesca, Beishuizen, Cathrien B, Jongstra, Susan, van Middelaar, Tessa, Van Wanrooij, Lennard L, Ngandu, Tiia, Guillemont, Juliette, Andrieu, Sandrine, Brayne, Carol, Kivipelto, Miia, Soininen, Hilkka, and Van Gool, Willem A

Published
2019
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