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7. NDSE Static Series V & VI Test Results

Author

DeYoung, Anemarie, primary, Yuan, Vincent, additional, Morgan, George, additional, Anderson, Richard, additional, Beller, Timothy, additional, Cooper, Andrew, additional, Cutler, Theresa, additional, Dinwiddie, Derek, additional, Dugan, Timothy, additional, Durkee, Eloura, additional, Goda, Joetta, additional, Gonzales, Samuel, additional, Grove, Travis, additional, Hayes, David, additional, Hutchinson, Jesson, additional, Kamm, Ryan, additional, Kinsey, Tanya, additional, Lash, Donald, additional, LeCounte, Ryan, additional, Lewis, Donnette, additional, Lynn, Alexander, additional, Martin, Justin, additional, McKenzie, George, additional, McSpaden, Alexander, additional, Mitchell, Mark, additional, Myers, William, additional, Parsons, Justin, additional, Perlstein, Daniel, additional, Romero, Christopher, additional, Smith, Travis, additional, Spirodek, Lauren, additional, Stults, Katrina, additional, Trujillo, Leonard, additional, Valdez, Kenneth, additional, Walker, Jessie, additional, Wynne, Nicholas, additional, Sipe, Nathan, additional, Friedman, Joshua, additional, Lowe, Daniel, additional, Beaulieu, Ronald, additional, Biancaniello, Pasqualina, additional, Blasco, Michael, additional, Breeding, Kathy, additional, Buckles, Robert, additional, Constantino, Derek, additional, Crawford, Kristin, additional, Dalley, Dennis, additional, Gall, Brady, additional, Garza, Irene, additional, Green, J., additional, Guckes, Amber, additional, Hagan, E., additional, Heika, Michael, additional, Huffines, Gary, additional, Irvin, James, additional, Manuel, Collin, additional, McLin, Kale, additional, Meehan, Timothy, additional, Mitlyng, Al, additional, Molnar, Steve, additional, Robbins, Larry, additional, and Tinsley, Jim, additional

Published
2020
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8. Oncologic Safety of Close Margins in Patients With Low- to Intermediate-Grade Major Salivary Gland Carcinoma.

Author

Sajisevi, Mirabelle, Nguyen, Kenny, Callas, Peter, Holcomb, Andrew J., Vural, Emre, Davis, Kyle P., Thomas, Carissa M., Plonowska-Hirschfeld, Karolina A., Stein, John S., Eskander, Antoine, Kakarala, Kiran, Enepekides, Danny J., Hier, Michael P., Ryan, William R., Asarkar, Ameya A., Aulet, Ricardo, Bell, Rebecca K., Blasco, Michael A., Bowmaster, Vanessa B., and Burruss, Clayton P.

Published
2024
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9. Nevada National Security Site Site-Directed Research and Development Report (FY 2018 Annual Report)

Author

Bender, III, Howard, primary, Hixson, Robert, additional, Thomas, Sarah, additional, La Lone, Brandon, additional, Turley, Dale, additional, Hawkins, Cameron, additional, Stevens, Gerald, additional, Veeser, Lynn, additional, Fensin, Saryu, additional, Jones, David, additional, Trainham, Rusty, additional, Guss, Paul, additional, Manard, Manuel, additional, McLean, Lance, additional, Kaye, Willy, additional, Kochersbergere, Kevin, additional, Capelle, Gene, additional, Mance, Jason, additional, Dutra, Eric, additional, Koch, Jeffrey, additional, Presura, Radu, additional, Wiemior, Piotr, additional, Darling, Timothy, additional, Mancini, Roberto, additional, Covington, Aaron, additional, Tschauner, Oliver, additional, Fussell, Zachary, additional, McClure, Jason, additional, Hooks, Daniel, additional, Smith, Jesse, additional, Scharff, Jason, additional, Grover, Mike, additional, Staska, Matt, additional, Valencia, Ruben, additional, Essex, James, additional, Okada, Colin, additional, Podovich, Aaron, additional, Reed, Michael, additional, Guild-Bingham, Avery, additional, Haber, Dan, additional, Gall, Brady, additional, Heika, Michael, additional, Blasco, Michael, additional, Bellow, Joseph, additional, Meehan, Bernard, additional, DiPuccio, Vincent, additional, Wolverton, Adam, additional, Tinsley, James, additional, Bennett, Nichelle, additional, Green, J., additional, Schwellenbach, David, additional, Lipton, Ron, additional, Rubinov, Paul, additional, Gingu, Cristinel, additional, Utes, Michael, additional, Cooper, William, additional, Green, Johnny, additional, Gonzalez, Humberto, additional, Marchan, Miguelangel, additional, Glasser, Vale, additional, Opachich, Kathy, additional, MacPhee, Andrew, additional, Landen, Otto, additional, Chen, Ning, additional, Gopal, Ashwini, additional, Udin, Salah, additional, Hilsabeck, Terry, additional, Huffman, Eric, additional, Feng, Jun, additional, Bradley, Dave, additional, Nagel, Sabrina, additional, Burt, Chris, additional, Lawson, Janice, additional, Ford, Bill, additional, O’Neill, Mary, additional, Moore, Eric, additional, Luttman, Aaron, additional, Constantino, Derek, additional, Catenacci, Jared, additional, Hoeller, Margaret, additional, Hoff, Tori, additional, Trone, Doug, additional, Delgado, Alexander, additional, Jackson, Emily, additional, Hock, Margaret, additional, Adams, Jesse, additional, Martin, Ryan, additional, Hague, Emma, additional, Turk, Johanna, additional, Clayton, Daniel, additional, Guerrero, Daniel, additional, Kruschwitz, Craig, additional, Stutman, Dan, additional, Tritz, Kevin, additional, King, James, additional, Freeman, Richard, additional, Madajian, Jonathan, additional, and Larson, Eric, additional

Published
2018
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10. Radiologic–pathologic correlation of major versus minor extranodal extension in oral cavity cancer

Author

Blasco, Michael A., primary, Noel, Christopher W., additional, Truong, Tra, additional, Huang, Shao Hui, additional, Goldstein, David P., additional, Irish, Jonathan C., additional, Gilbert, Ralph, additional, Hosni, Ali, additional, Hope, Andrew, additional, O'Sullivan, Brian, additional, Waldron, John, additional, Perez‐Ordonez, Bayardo, additional, Weinreb, Ilan, additional, Smith, Stephen M., additional, Bartlett, Eric, additional, Yu, Eugene, additional, and Almeida, John R., additional

Published
2022
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13. Source and Diagnostic Development for a Neutron Diagnosed Subcritical Experiment

Author

Bennett, Nichelle, primary, Blasco, Michael, additional, Breeding, Kathy, additional, Constantino, Derek, additional, DiPuccio, Vincent, additional, Friedman, Joshua, additional, Gall, Brady, additional, Gardner, Steven, additional, Gatling, James, additional, Luttman, Aaron, additional, Malone, Robert, additional, Meehan, Bernard, additional, Misch, Michael, additional, Molnar, Stephen, additional, Sipe, Nathan, additional, and Tinsley, Jim, additional

Published
2016
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14. Role of Migratory Inhibition Factor in Age-Related Susceptibility to Radiation Lung Injury via NF-E2-Related Factor-2 and Antioxidant Regulation

Author

Mathew, Biji, Jacobson, Jeffrey R., Siegler, Jessica H., Moitra, Jaideep, Blasco, Michael, Xie, Lishi, Unzueta, Crystal, Zhou, Tong, Evenoski, Carrie, Al-Sakka, Mohammed, Sharma, Rajesh, Huey, Ben, Bulent, Aydogan, Smith, Brett, Jayaraman, Sundararajan, Reddy, Narsa M., Reddy, Shekhar P., Fingerle-Rowson, Günter, Bucala, Richard, Dudek, Steven M., Natarajan, Viswanathan, Weichselbaum, Ralph R., and Garcia, Joe G. N.

Published
2013
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15. Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery.

Author

Goldstein, David P., Blasco, Michael, de Almeida, John, Su, Jie, Xu, Wei, Cohen, Marc, Sklar, Michael, and Alibhai, Shabbir

Abstract

The study objective was to measure the prevalence and predictors of cognitive impairment (CI) and delirium. Adults undergoing major head and neck cancer surgery completed the Clock Draw Test to screen for CI, defined as a score of 0 or 1. Postoperative delirium was recorded. Predictors of delirium and length of stay were assessed by univariate logistic regression and the latter with multivariate linear regression. Overall 274 patients were included, of which 47% had a Clock Draw Test score of 0 or 1. Post-operative delirium occurred in 17 (6%). CI was a predictor of postoperative delirium (odds ratio, 3.9; 95% CI, 1.2-12; P =.02). Postoperative delirium was a predictor of increased length of stay (adjusted odds ratio, 1.30; 95% CI, 1.07-1.57; P =.0073) on multivariate regression while baseline Clock Draw Test result was not a predictor on univariate regression (P =.98). Screening for CI can help predict delirium and facilitate targeted interventions in the postoperative period. [ABSTRACT FROM AUTHOR]

Published
2022
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17. Rattled

Author

Blasco, Michael A., primary, Kandinov, Aron, additional, Svider, Peter F., additional, Gonik, Nathan J., additional, Hanba, Curtis, additional, Zuliani, Giancarlo F., additional, Shkoukani, Mahdi A., additional, and Carron, Michael A., additional

Published
2017
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20. Rattled

Author

Blasco, Michael A., Kandinov, Aron, Svider, Peter F., Gonik, Nathan J., Hanba, Curtis, Zuliani, Giancarlo F., Shkoukani, Mahdi A., and Carron, Michael A.

Abstract

Supplemental digital content is available in the text.

Published
2020
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21. Head and Neck Cancer: Underfunded and Understudied?

Author

Svider, Peter F., primary, Blasco, Michael A., additional, Raza, S. Naweed, additional, Shkoukani, Mahdi, additional, Sukari, Ammar, additional, Yoo, George H., additional, Folbe, Adam J., additional, Lin, Ho‐Sheng, additional, and Fribley, Andrew M., additional

Published
2016
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25. Oncologic Safety of Close Margins in Patients With Low- to Intermediate-Grade Major Salivary Gland Carcinoma.

Author

Sajisevi M, Nguyen K, Callas P, Holcomb AJ, Vural E, Davis KP, Thomas CM, Plonowska-Hirschfeld KA, Stein JS, Eskander A, Kakarala K, Enepekides DJ, Hier MP, Ryan WR, Asarkar AA, Aulet R, Bell RK, Blasco MA, Bowmaster VB, Burruss CP, Chung J, Chan K, Chang BA, Coffey CS, Cognetti DM, Cooper DJ, Cordero J, Donovan J, Du YJ, Dundar Y, Dedivitis RA, Edwards HA, Erovic BM, Feinberg PA, Garvey EA, Goldstein DP, Goodman JF, Goulart RN, Goyal N, Grasl S, Giurintano JP, Gupta N, Habib AM, Hackman TG, Hara JH, Henson C, Hinni ML, Hua N, Johnson-Obaseki S, Juloori A, Kalman NS, Kejner AE, Khaja SF, Ku JA, Lambert A, Luu BK, Magliocca KR, Dos Santos LRM, Michael C, Miles BA, de Melo GM, Moore MG, Morand GB, Moura K, Mukdad L, Noroozi H, Patel R, Paydarfar JA, Sadeghi N, Savaria FN, Schmitt NC, Shapiro J, Shaver TB, Stoeckli SJ, St John M, Stokes WA, Sulibhavi A, Tasoulas J, Vendra V, Vinh DB, Virgen CG, Wooten C, Woody NM, and Young GD

Subjects
Humans, Male, Female, Infant, Adult, Middle Aged, Aged, Retrospective Studies, Cohort Studies, Margins of Excision, Carcinoma surgery, Salivary Gland Neoplasms radiotherapy, Salivary Gland Neoplasms surgery, Salivary Gland Neoplasms pathology
Abstract

Importance: Postoperative radiation therapy for close surgical margins in low- to intermediate-grade salivary carcinomas lacks multi-institutional supportive evidence., Objective: To evaluate the oncologic outcomes for low- and intermediate-grade salivary carcinomas with close and positive margins., Design, Setting, and Participants: The American Head and Neck Society Salivary Gland Section conducted a retrospective cohort study from 2010 to 2019 at 41 centers. Margins were classified as R0 (negative), R1 (microscopically positive), or R2 (macroscopically positive). R0 margins were subclassified into clear (>1 mm) or close (≤1 mm). Data analysis was performed from June to October 2023., Main Outcomes and Measures: Main outcomes were risk factors for local recurrence., Results: A total of 865 patients (median [IQR] age at surgery, 56 [43-66] years; 553 female individuals [64%] and 312 male individuals [36%]) were included. Of these, 801 (93%) had parotid carcinoma and 64 (7%) had submandibular gland carcinoma, and 748 (86%) had low-grade tumors and 117 (14%) had intermediate-grade tumors, with the following surgical margins: R0 in 673 (78%), R1 in 168 (19%), and R2 in 24 (3%). Close margins were found in 395 of 499 patients with R0 margins (79%), for whom margin distances were measured. A total of 305 patients (35%) underwent postoperative radiation therapy. Of all 865 patients, 35 (4%) had local recurrence with a median (IQR) follow-up of 35.3 (13.9-59.1) months. In patients with close margins as the sole risk factor for recurrence, the local recurrence rates were similar between those who underwent postoperative radiation therapy (0 of 46) or observation (4 of 165 [2%]). Patients with clear margins (n = 104) had no recurrences. The local recurrence rate in patients with R1 or R2 margins was better in those irradiated (2 of 128 [2%]) compared to observed (13 of 64 [20%]) (hazard ratio [HR], 0.05; 95% CI, 0.01-0.24). Multivariable analysis for local recurrence found the following independent factors: age at diagnosis (HR for a 10-year increase in age, 1.33; 95% CI, 1.06-1.67), R1 vs R0 (HR, 5.21; 95% CI, 2.58-10.54), lymphovascular invasion (HR, 4.47; 95% CI, 1.43-13.99), and postoperative radiation therapy (HR, 0.10; 95% CI, 0.04-0.29). The 3-year local recurrence-free survivals for the study population were 96% vs 97% in the close margin group., Conclusions and Relevance: In this cohort study of patients with low- and intermediate-grade major salivary gland carcinoma, postoperative radiation therapy for positive margins was associated with decreased risk of local recurrence. In isolation from other risk factors for local recurrence, select patients with close surgical margins (≤1 mm) may safely be considered for observation.

Published
2024
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