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Background There is scarce evidence on the fourth dose of severe acute respiratory syndrome coronavirus 2 vaccines in chronic kidney disease (CKD) patients. We evaluated the humoral response and effectivity of the fourth dose in the CKD spectrum: non-dialysis CKD (ND-CKD), haemodialysis (HD), peritoneal dialysis (PD) and kidney transplant (KT) recipients. Methods This is a prespecified analysis of the prospective, observational, multicentric SENCOVAC study. In patients with CKD who had received a complete initial vaccination and one or two boosters and had anti-Spike antibody determinations 6 and 12 months after the initial vaccination, we analysed factors associated with persistent negative humoral response and higher anti-Spike antibody titres as well as the efficacy of vaccination on coronavirus disease 2019 (COVID-19) severity. Results Of 2186 patients (18% KT, 8% PD, 69% HD and 5% ND-CKD), 30% had received a fourth dose. The fourth dose increased anti-Spike antibody titres in HD (P = .001) and ND-CKD (P = .014) patients and seroconverted 72% of previously negative patients. Higher anti-Spike antibody titres at 12 months were independently associated with repeated exposure to antigen (fourth dose, previous breakthrough infections), previous anti-Spike antibody titres and not being a KT recipient. Breakthrough COVID-19 was registered in 137 (6%) patients, 5% of whom required admission. Admitted patients had prior titres Conclusions A fourth vaccine dose increased anti-Spike antibody titres or seroconverted many CKD patients, but those with the highest need for a vaccine booster (i.e. those with lower pre-booster antibody titres or KT recipients) derived the least benefit in terms of antibody titres. Admission for breakthrough COVID-19 was associated with low anti-Spike antibody titres.

Introducción. Hoy en día existe una mayor conciencia de las desigualdades presentes en la sociedad, lo que ha llevado a ampliar el concepto de pobreza tradicional, y con ello, a la generación de nuevas y más integrales formas de medición de la misma, como lo es la medición de pobreza multidimensional. No obstante, a pesar de los avances que esto ha significado, la propuesta deja fuera aspectos relacionales importantes que son necesarios de considerar por los graves efectos de la pobreza en la vida de las personas, en especial de niños y niñas, provocados en parte, por el estrés crónico que la misma tiene el potencial de generar en las figuras cuidadoras. A razón de lo anterior, esta investigación se propuso establecer la relación existente entre el estrato socioeconómico, como medida tradicional de medición, y de la pobreza multidimensional, con el estrés parental. Metodología. Estudio cuantitativo descriptivo de corte transversal con una muestra de madres y padres chilenos (n=180), seleccionados por medio de un muestreo no probabilístico por cuotas, que respondieron preguntas sobre su situación socioeconómica y presencia o ausencia de carencias vinculadas a la medición de pobreza multidimensional, junto a la escala Parental Stress Index en su versión reducida (PSI-SF). Resultados. Los resultados de las correlaciones y regresiones lineales múltiples realizadas, mostraron que en la medida que aumenta el porcentaje de pobreza multidimensional, tiende a aumentar el estrés parental. Cuando la pobreza multidimensional está en interacción con el género, tipo de hogar y número de hijos y/o hijas, el modelo aumenta su bondad de ajuste logrando predecir un mayor porcentaje del puntaje de estrés parental. Al aumentar el porcentaje de pobreza multidimensional, quienes presentan un puntaje más elevado de estrés parental son las participantes de género femenino que no viven con sus hijos y/o hijas y que tienen tres hijos y/o hijas, seguido de quienes son de género femenino, que viven en hogares extensos biparentales y que tienen tres hijos y/o hijas. El efecto de un elevado porcentaje de pobreza multidimensional sobre el estrés parental es mayor en las entrevistadas que presentan como característica ser de género femenino, pertenecientes a un hogar biparental extenso y que tienen tres hijos y/o hijas. Discusión. Se discuten los resultados en torno a la importancia de los hallazgos y la relación de estos en base a otra evidencia científica disponible. Conclusión. Se aprecia que la relación de la pobreza multidimensional con estrés parental es más extendida que la de estrato socioeconómico, y un papel importante en la explicación de la misma tiene la presencia de otras variables sociodemográficas, especialmente tipo de hogar y número de hijos y/o hijas. Introduction. Today, there is a greater awareness of society’s inequalities. This has led to extending the traditional concept of poverty and new, more comprehensive measurement methods, such as multidimensional poverty measurement. Nevertheless, despite the advances made, the proposal leaves out important relational aspects that need to be considered. Indeed, poverty can have severe effects on people’s lives, especially children, owing partly to the chronic stress that poverty can generate in caregivers. As a result, in this study, we sought to establish the relationship between socioeconomic status, as a traditional measure, and multidimensional poverty with parental stress. Methodology. A cross-sectional descriptive quantitative study was conducted. A sample of Chilean mothers and fathers (n=180) was selected through non-probability quota sampling. Participants answered questions about their socioeconomic situation and the presence or absence of deprivations linked to multidimensional poverty measurement and the reduced version of the Parental Stress Index (PSI-SF). Results. The results of the correlations and multiple linear regressions performed showed that parental stress tended to rise as the multidimensional poverty percentage increased. When multidimensional poverty interacted with gender, household type, and number of children, the model improved its goodness-of-fit, predicting a higher percentage of the parental stress score. As the percentage of multidimensional poverty increased, those with higher parental stress scores corresponded to female participants who did not live with their children and had three children, followed by female participants who lived in large two-parent households and had three children. The effect of high multidimensional poverty on parental stress was greater in female respondents belonging to large two-parent households with three children. Discussion. The results are discussed in relation to the importance of the findings and their relationship with other available scientific evidence. Conclusion. Multidimensional poverty is more strongly related to parental stress than socioeconomic status. In addition, the presence of other sociodemographic variables, especially household type and number of children, play a significant role in explaining this relationship. Este trabajo fue financiado por la Agencia Nacional de Investigación y Desarrollo de Chile (Subdirección de Capital Humano) (CONICYT/ANID) / Programa de Formación de Capital Humano Avanzado/Doctorado Beca Nacional 2017-21170152.

Background Patients on hemodialysis are at high-risk for complications derived from coronavirus disease 2019 (COVID-19). The present analysis evaluated the impact of a booster vaccine dose and breakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on humoral immunity 3 months after the booster dose. Methods This is a multicentric and prospective study assessing immunoglobulin G anti-Spike antibodies 6 and 9 months after initial SARS-CoV-2 vaccination in patients on hemodialysis that had also received a booster dose before the 6-month assessment (early booster) or between the 6- and 9-month assessments (late booster). The impact of breakthrough infections, type of vaccine, time from the booster and clinical variables were assessed. Results A total of 711 patients [67% male, median age (range) 67 (20-89) years] were included. Of these, 545 (77%) received an early booster and the rest a late booster. At 6 months, 64 (9%) patients had negative anti-Spike antibody titers (3% of early booster and 29% of late booster patients, P = .001). At 9 months, 91% of patients with 6-month negative response had seroconverted and there were no differences in residual prevalence of negative humoral response between early and late booster patients (0.9% vs 0.6%, P = .693). During follow-up, 35 patients (5%) developed breakthrough SARS-CoV-2 infection. Antibody titers at 9 months were independently associated with mRNA-1273 booster (P = .001), lower time from booster (P = .043) and past breakthrough SARS-CoV-2 infection (P < .001). Conclusions In hemodialysis patients, higher titers of anti-Spike antibodies at 9 months were associated with mRNA-1273 booster, lower time from booster and past breakthrough SARS-CoV-2 infection.Lay Summary Patients on hemodialysis present higher rates of complications derived from SARS-CoV-2 infections. Initial vaccination schedules have demonstrated suboptimal responses in those patients. The aim of the present study is to evaluate the time-course of the humoral response after a booster dose of SARS-CoV-2 RNA-based vaccines (BNT162b2 or mRNA-1273) in patients on hemodialysis. We included 711 patients that had received a booster dose: 545 (77%) 6 months before the initial vaccination and 166 (23%) between 6 and 9 months from the initial vaccination. After the booster, only 6 (

The relationship between being a parent and personal well-being has been the topic of interest and debate in recent decades. However, most of the studies in this field are from high-income countrie...

Background and importance A limited number of studies have related serum biological levels to clinical response in psoriasis. Studies on the clinical relevance of therapeutic drug monitoring for etanercept biosimilar (ETAb) are scarce. Aim and objectives To analyse ETAb concentrations in patients with moderate to severe plaque psoriasis. Material and methods This was an observational retrospective study of all psoriatic patients treated with ETAb (Erelzi) and monitored in the pharmacy service from January 2018 to September 2019. The ethics committee approved this study. Informed consent was obtained for all subjects before entry into the study. Patients received ETAb 50 mg every week. ETAb serum levels were assessed immediately prior to administration of drug (Ctrough). Concentrations were quantified by capture ELISA immunoassay (Triturus analyser). Data sources sex, age, weight, date of psoriasis diagnosis, previous treatment with biologic drugs, duration of ETAb treatment, dosage/weight (mg/kg), concomitant treatment (immunosuppressive drugs, oral corticosteroids, retinoids), psoriasis area and severity index scale (PASI) before the start of ETAb treatment (PASIb) and at blood extraction time (PASIe), ETAb concentration and adverse events. Patients were classified into two groups in accordance with efficacy at the various blood assessment times: good responders (>PASI75) and non-responders ( Statistics descriptive analysis of variables (SPSS V.19.0), quantitative variables (median (range)) and qualitative variables (number (percentage)). Results Ten patients (70.0% men, 28 blood samples) were aged 48.5 (26.0–68.0) years and weighed 73 (64–112) kg. Dosage/weight was 0.7 (0.5–0.8) mg/kg. Age at diagnosis was 25.5 (8.0–47.0) years and 100% were naive patients. Concomitant treatments were methotrexate (n=3) and ciclosporin (n=1). PASIb was 9.0 (3.0–17.3) and PASIe 1.2 (0.0–14.8), 14/28 PASIe=0.0 and%PASI variation with respect to basal value 92.3 (−82.7–100). Treatment time at blood extraction was 3.9 (0.9–14.0) months. ETAb concentration was 2.7 (0.6–4.8) µg/mL. Efficacy: 57.1% good responders and 42.9% non-responders. There were no significant differences in demographic data between the patient response groups. There were no significant differences with respect to ETAb levels: 2.7 µg/mL (range 1.8–4.4) versus 2.6 µg/mL (range 0.6–4.8), respectively (p>0.05). No adverse events were reported. Conclusion and relevance Drug concentrations were detected in all patients. No relationship was found between ETAb concentration and clinical response (efficacy and toxicity). Further research is needed to determine the clinical significance between ETAb concentration and clinical response, and hence the usefulness of therapeutic drug monitoring in psoriatic patients. References and/or acknowledgements No conflict of interest.

El objetivo de este proyecto es diseñar y desarrollar una interfaz avanzada para el control de un robot escalador. El diseño de la interfaz se ha realizado siguiendo un patrón de diseño de desacoplamiento, de forma que pueda ser fácilmente aplicado a, cualquier otro robot que utilice el mismo modelo de servicios y datos de comunicación. En concreto se ha aplicado al robot hexapodo del proyecto ROMERIN. El Robot Romerín es un robot hexápodo escalador, que gracias a las ventosas con turbinas que tiene alojadas en sus patas, es capaz de adherirse a las superficies. El control del mismo se realiza en ROS (Robot Operating System) La interfaz está pensada para ser utilizada en tabletas, ha sido desarrollada para el sistema operativo Android, tiene la capacidad de poder conectarle un dispositivo de entrada, de tipo gamepad y si no se dispone de uno, se crea uno de forma virtual, se comunica con los servicios ya creados en otros proyectos anteriores del robot mediante RosJava. Esta interfaz también es capaz de conectarse con la simulación de V-REP para poder realizar pruebas y después poder replicarlas en el robot real.

151 páginas En la industria de telecomunicaciones, los departamentos tecnológicos son fundamentales para el desarrollo y el sostenimiento de la operación; son divisiones que soportan el core de negocio, ayudan a la estrategia de la compañía a cumplir sus objetivos; sin embargo y a pesar que los directivos conocen la importancia de ser un departamento estratégico, en algunas ocasiones no identifican cual es la mejor forma para definir un correcto plan de acción y apalancar la empresa en un entorno competitivo. Esto conlleva muchas veces en la generación de problemas en la operación, temores, desorientación, desalineación y toma de decisiones incorrectas, causando problemas en la comunicación entre Negocio e IT y generando el no cumplimiento de los objetivos estratégicos. Es por esto por lo que actualmente el sector de las telecomunicaciones busca que las áreas de Tecnología sean estratégicas y propositivas, generando mayor productividad, dinamismo y agilidad; lo que les permite aprovechar las ventanas de oportunidad que emergen en el mercado, generando un diferenciador para la industria, con el fin de solucionar esta problemática este trabajo de grado propone la adopción y mejora continua bajo el framework de trabajo TOGAF de Arquitectura empresarial. In the telecommunications industry, technology departments are essential for the development and maintenance of the operation; they are divisions that support the core business, help the company's strategy to meet its objectives; However, and despite the factthat managers know the importance of being a strategic department, they sometimes do not identify the best way to define a correct action plan and leverage the company in a competitive environment. This often leads to the generation of problems in the operation, fears, disorientation, misalignment and incorrect decision making, causing problems in communication between Business and IT and generating non-compliance with strategic objectives. That is why the telecommunications sector is currently looking for technology areas to be strategic and purposeful, generating greater productivity, dynamism and agility; which allows them to take advantage of the windows of opportunity that emerge in the market, generating a differentiator for the industry, in order to solve this problem, this degree work proposes the adoption and continuous improvement under the TOGAF framework of Enterprise Architecture. Maestría Magíster en Gerencia Estratégica de Tecnologías de Información

Las plantas siguen siendo una fuente fundamental en la investigación de nuevos fármacos, Todo comienza con la investigación etnobotánica de base -respetuosa y responsable en comunidades indígenas, mestizas o rurales. Los biólogos son profesionales que tienen mucho que decir en todos los pasos del largo y complejo recorrido que va desde la planta al medicamento. Ponemos algunos ejemplos vigentes y otros promisorios o prometedores. Sin financiación No data 2019 UEM

New data of flora and taxonomic nomenclature for the catalogue of the autonomic community of Cantabria are apported

[ES] El crecimiento de las webs permite que los usuarios tengan una mayor elección a la hora de decidir donde navegar por internet. La importancia de disponer de un sitio web con un nivel adecuado de usabilidad y accesibilidad, es que permite que éste pueda ser accedido por una mayor cantidad de usuarios. Para una Universidad, esta es una de las puertas más importantes para darse a conocer. Además, es uno de los pilares fundamentales de una universidad más abierta. Sin embargo, hasta el momento previo a este TFM, no se había realizado ningún estudio de usabilidad y accesibilidad en la web de la Universidad Católica de Valencia. En este trabajo, se realizó un análisis de la facilidad de aprendizaje, eficiencia, satisfacción y eficacia con respecto a la usabilidad de la web de la Universidad Católica de Valencia. Además, se estudió si el sitio es perceptible, operable, comprensible y robusto en relación con la accesibilidad. Para realizar el estudio, se han usado las metodologías de heurísticas y UWEM. Asimismo, se utilizaron herramientas tecnológicas como son W3C Unicon, T.A.W., eXaminator, WAVE y SortSite. La Universidad obtuvo como resultado un nivel del 83,47% en usabilidad y un nivel de entre el 50% y el 80% en accesibilidad. Adicionalmente, se desarrolló una herramienta para personas con deficiencia visual. La herramienta les permite cambiar el contraste y aumentar o disminuir el tamaño de las letras en los contenidos del sitio web de la Universidad Católica de Valencia. Facilitando así a estas personas realizar una mejor lectura de la información., [EN] The growth of websites allows users to have a greater choice when it comes to navigating on the internet. The importance of having a website with an adequate level of usability and accessibility is that it allows a larger number of users to access it. For a university, this is one of the most important means of becoming known and a fundamental aspect of a more open University. However, before to this TFM, a study of the usability and accessibility of the website of the Universidad Católica de Valencia had not been carried out. In this research, an analysis of the easiness of learning, the efficiency, the satisfaction, and the effectiveness concerning the usability of the website of the Universidad Católica de Valencia was performed. In addition, it was evaluated whether the site is perceptible, operable, understandable and robust regarding accessibility. For this purpose, the heuristics and UWEM methodologies were used, as well as various technological tools such as W3C Unicon, TAW, eXaminator, WAVE, and SortSite. The University website obtained a level of 83.47% in usability and a level of between 50% and 80% in accessibility. In addition, a tool for people with visual impairment was developed. The tool allows them to change the contrast and increase or decrease the size of the letters in the contents of the website of the University. This facilitates a better reading of the information.

La diabetes es un trastorno metabólico que se caracteriza por niveles altos de glucosa en sangre debido a una resistencia insulínica o ausencia total de la misma. Existen principalmente dos tipos de diabetes, la tipo 1 asociada a la ausencia total de insulina y la tipo 2 asociada a resistencia insulínica la cual representa más del 90 porciento de los diagnósticos 1. Diversos estudios demuestran que el cortisol juega un papel importante en la progresión y aparición de esta enfermedad por lo que se están buscando formas de controlar los niveles de cortisol en pacientes con diabetes mellitus tipo 2, una de ellas es mediante la inhibición de la enzima 11β-hidroxiesteroide deshidrogenasa tipo 1 11B HSD1, la cual cataliza la formación de cortisol a partir de cortisona, además se ha evidenciado que esta enzima es inhibida por una fracción de moléculas conocidas como triterpenos pentacíclicos, los cuales están presentes en las raíces de una planta llamada Cecropia telenitida 2. Actualmente se están estudiando los productos naturales como fracciones de composición conocida y que tengan un efecto terapéutico reproducible, por lo que este proyecto tiene como objetivo identificar y purificar una fracción de triterpenos pentacíclicos provenientes de las raíces de Cecropia telenitida como hit inhibitorio de la enzima 11B HSD1.

Este estudio pretende analizar el conocimiento adquirido por el alumnado de 4º de psicología sobre atención a la diversidad, los modelos educativos de integración e inclusión y las necesidades específicas de apoyo educativo que pueden presentar los niños durante su desarrollo; todo ello con el objetivo de asegurar que los actuales estudiantes de psicología, y futuros profesionales del ámbito educativo, dispongan de un conocimiento correcto; así, próximamente, las escuelas podrán disponer de profesionales bien formados que sean capaces de adaptar las enseñanzas didácticas a la situación de cada niño y de poder responder a sus necesidades educativas satisfactoriamente. Para ello, se realizó una recogida de datos a través de un instrumento cuantitativo creado ad hoc para analizar tanto el conocimiento adquirido por el alumnado de psicología sobre atención a la diversidad, como las posibles variables personales que pueden estar relacionadas con la calidad de dicho conocimiento. El análisis del conocimiento de los estudiantes muestra conclusiones positivas sobre este, aunque no se acerca del todo al modelo teórico; por otro lado, el análisis de las variables muestra una clara relación entre el conocimiento y la formación recibida, no existiendo dicha relación con la edad, el interés por la educación o la proximidad a personas con NEAE. This study aims to analyse the acquired knowledge by the students of 4th year of psychology about diversity awareness, integration and inclusion educative models, and the specific needs for educational support that can show some children through development; the main objective is to asure that current psychology students and future professionals of the educational field have the necessary knowledge. Consequently, the schools will have the opportunity to have well trained professionals that are capable to adapt didactic instructions to every child’s situation and to meet their educational needs sactisfactorily. To achieve this, we carried out a data collection with a cuantitative tool created ad hoc to analyse the acquired knowledge by the psychology students about diversity awareness, as well as personal variables that can be related to the quality of this knowledge. The analysis of the student’s knowledge shows optimist conclussions about this, although it hasn’t approached the theoretical model; on the other hand, the analysis of the variables shows a clear relationship between the knowledge and the received training, as well as no relationship with age, interest for education, or proximity to children that show specific needs for educational support. Universidad de Sevilla. Grado en Psicología

Two very important taxa of floristic and chorologic interest: Aster linosyris (L.) Bernh.,and Gymnocarpium dryopteris (L.) Newman are quoted for the first time in Avila (C Spain). We also present new references for other interesting species like Juniperus thurifera L. and Taxus baccata L. Photos and chorologic materials, maps of both discoveries with directions about their location are provided, as well as their coordinates in grids UTM of 10×10 km.

Se citan por primera vez en Ávila, Aster linosyris (L.) Bernh., y Gymnocarpium dryopteris (L.) Newman; dos táxones relevantes de interés florístico y corológico. Además se dan citas poco conocidas de localizaciones de otros táxones de interés como Juniperus thurifera L. o Taxus baccata L. Se aporta material fotográfico y mapas corológicos de las 2 novedades y de Juniperus thurifera, con indicación de las localidades en cuadrícula UTM de 10×10 km. Two very important taxa of floristic and chorologic interest: Aster linosyris (L.) Bernh.,and Gymnocarpium dryopteris (L.) Newman are quoted for the first time in Avila (C Spain). We also present new references for other interesting species like Juniperus thurifera L. and Taxus baccata L. Photos and chorologic materials, maps of both discoveries with directions about their location are provided, as well as their coordinates in grids UTM of 10×10 km. Sin financiación No data JCR 2017 0.207 SJR (2017) Q3, 351/483 Plant Science, 292/391 Ecology No data IDR 2017 UEM

Se aportan datos sobre los robledales del sur de Cantabria y centro-norte de la provincia de Burgos, en especial sobre los mesoéutrofos de Quercus robur y Q. pyrenaica. Data about the oak forests of the south of the Autonomic Community of Cantabria and the center and the north of the province of Burgos are aported, with especial attention to the meso-eutrophic forests of Quercus robur and Q. pyrenaica. SIN FINANCIACIÓN No data JCR 2017 0.207 SJR (2017) Q3, 351/483 Plant Science, 292/391 Ecology No data IDR 2017 UEM

Oncidiinae é uma das principais subtribos de Orchidaceae em número de representantes dentro da região Neotropical. As relações taxonômicas e filogenéticas entre as espécies da subtribo sempre foram controversas, sendo recentemente esclarecidas após o desenvolvimento de filogenias baseadas em caracteres moleculares. Como resultado, muitos gêneros foram atestados como não monofiléticos, entre eles Oncidium Sw., o gênero tipo da subtribo. As espécies brasileiras do gênero foram, então, transferidas para um conceito amplo de Gomesa R.Br., a fim de gerar grupos monofiléticos. Como atualmente aceita, Gomesa abrange 133 espécies do Brasil. Após observações de campo e revisão de literatura e herbários, foi detectada a necessidade de realização de tipificações e sinônimos sobre as espécies do sul do Brasil. Portanto, fornecemos uma lista de 20 holótipos, 3 isótipos, 8 síntipos, 16 lectótipos, 1 isolectótipo e 2 neótipos. Os novos sinônimos propostos são Gomesa montana (= G. barbaceniae); G. ciliata (= G. barbata); Oncidium raniferum var. major e G. loefgrenii (= G. hookeri); G. gravesiana (= G. imperatoris-maximiliani); G. gardneri (= G. pectoralis); G. planifolia (= G. recurva); e G. longipes (= G. uniflora). Após o conhecimento das identidades das espécies, realizamos uma sinopse de Gomesa no Estado do Rio Grande do Sul. Neste estudo, vinte espécies foram descritas, ilustradas e mapeadas. Pudemos observar que a riqueza específica é maior nas regiões leste e norte, enquanto diminui em direção ao oeste e sul. Em relação à lista de espécies previamente citadas para Estado, devem ser suprimidos 13 nomes e acrescentados três: Gomesa barbaceniae, G. imperatoris-maximiliani e G. pectoralis. Além disso, foram estudadas as estratégias de polinização e os sistemas reprodutivos de duas espécies representativas, Gomesa flexuosa e G. cornigera. Estas espécies oferecem óleos florais como recompensas a seus visitantes e são polinizadas por fêmeas de Centris trigonoides e Trigonopedia ferruginea, respectivamente. Ambas são polinizador-dependentes, mas fortemente auto-incompatíveis em relação aos seus sistemas de reprodução. Apesar de apresentarem altas porcentagens de frutificação por polinização cruzada em condições controladas (66,67% e 71,74%), suas eficiências de polinização são baixas, evidenciadas pelos índices de Nilsson de 0,27 e 0,35, que refletem em seus respectivos sucessos de frutificação. Esses fatores aliados aos comportamentos dos polinizadores, à provável ocorrência de auto-polinizações e a influência de características ecológicas resultam em baixas frutificações nas populações naturais, de no máximo 1,54% em Gomesa flexuosa e 6,10% em G. cornigera. Oncidiinae is one of the main subtribes of Orchidaceae in number of representatives within the Neotropics. The taxonomic and phylogenetic relationships among species within the subtribe have always been controversial, being recently clarified after the development of molecular-based phylogenies. As a result, many genera were proven not to be monophyletics, between them Oncidium Sw., the type genus. The Brazilian species of the former genus were, then, transferred to an expanded concept of Gomesa R.Br., in order to generate monophyletic groups. As currently accepted, Gomesa englobes 133 species in Brazil. After field observations and revision of literature and herbaria, we detected the need for typifications and synonyms concerning the species from Southern Brazil. Then, we provided a list of 20 holotypes, 3 isotypes, 8 syntypes, 16 lectotypes, 1 isolectotype and 2 neotypes. The new synonyms proposed are Gomesa montana (= G. barbaceniae); G. ciliata (= G. barbata); Oncidium raniferum var. major and G. loefgrenii (= G. hookeri); G. gravesiana (= G. imperatoris-maximiliani); G. gardneri (= G. pectoralis); G. planifolia (= G. recurva); and G. longipes (= G. uniflora). After the knowledge about the species identities, we performed a synopsis of Gomesa in Rio Grande do Sul, the southernmost State of Brazil. In this study, twenty species were described, illustrated and mapped. We were able to observe that the specific richness is higher at the eastern and northern regions while decreases towards the west and south. In relation to the list of species previously cited to the State, 13 names should be suppressed and 3 names added: Gomesa barbaceniae, G. imperatoris-maximiliani and G. pectoralis. Moreover, the pollination strategies and breeding systems of two representative species, Gomesa flexuosa and G. cornigera, were studied. These species offer floral oils as rewards to visitors and are pollinated by Centris trigonoides and Trigonopedia ferruginea, respectively. Both are pollinator-dependents, but strongly self-incompatibles regarding their breeding systems. Despite presenting high percentages of fruiting by cross-polinations under controlled conditions (66.67% and 71.74%), their pollination efficiencies are low, evidenced by the Nilsson’s indexes of 0.27 and 0.35, which reflect in their respective fruiting successes. These factors allied to the pollinators’s behaviors, the probable occurrence of self-pollinations and the influence of ecological features result in low fruit sets in natural populations, maximum of 1.54% in Gomesa flexuosa and 6.10% in G. cornigera.

Se aportan datos florísticos nuevos del catálogo supracitado, así como varios cambios taxonómicos. New data of flora and taxonomy for the catalogue of the autonomic community of Cantabria (N Spain) are apported.

An experimental study of an air-to-water reversible heat pump unit was carried out using two different fin-and-tube heat exchanger “coil” designs and propane (R290) as the working fluid. The main aim of these tests was to search for optimized coil design concepts. The performance of the heat pump was evaluated for each coil design at different superheat conditions at the inlet of the compressor in both modes of operation: heating and cooling. Coefficient of Performance (COP) in both modes of each heat pump unit using two different coil design are presented. Experimental measurements are compared against model predictions. The mean refrigerant side heat transfer coefficient and the pressure drop as a function of mass flux along the flow path are calculated. As a results of tests, it was found that the performance was obtained in the heat pump unit using coil-2 design with less refrigerant circuit and a higher length of circuit with a superheat of around 6 K in both modes of operation. From the calculation it was found that in both modes of operation coil-2 design gives higher heat transfer coefficients and pressure drops for the refrigerant side.

To determine whether early graft function after transplantation impacted graft and patient survivals.Between 1981 and 2008, we performed 1308 renal transplantations. Poor early graft function was defined as a Cockroft-Gault glomerular filtration rate60 mL/min or less at 1 and 3 months posttransplant. Patients who lost their kidney or died within the first 12 months after transplantation were excluded from the study. Multivariate statistical analysis used Cox proportional hazards models.Of the 1308 patients 994 (78.8%) displayed poor early graft function at 1 month after transplantation (glomerular filtration rate60 mL/min), while 268 (21.2%) showed normal function (glomerular filtration rate≥60 mL/min). The 2- and 6-year graft survival rates among the poor early graft function group were 96.8% and 85.8%, respectively, while those among the control group were 97.0% and 88.3%, respectively. The 2- and 6-year patient survival rates in the poor early graft function were 98.5% and 89.8% versus 98.9% and 96.3% in the control group. Similar results were observed at 3 months posttransplant. Controlling for patient age, donor age, HLA-AB and -DR mismatches, cold ischemia time, acute rejection episodes, cyclosporine therapy, and waiting time for transplantation, we did not observe early graft function to be a risk factor for graft survival or patient survival. Glomerular filtration rate at 2, 5, and 6 years after kidney transplantation was significantly lower in the poor early graft function than in the control group.This study suggested that the quality of early graft function had no significant effect on graft and patient survival rate, but did have a significant influence on long-term renal function.