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2. Yellow Fever Reemergence Risk in the Guiana Shield: a Comprehensive Review of Cases Between 1990 and 2022

Author

Thomas, Caroline, Michaud, Céline, Gaillet, Mélanie, Carrión-Nessi, Fhabián S., Forero-Peña, David A., Lacerda, Marcus Vinícius Guimarães, Duchemin, Jean-Bernard, Rodovalho, Sheila, Vreden, Stephen, Ramos, Ruth, Nacher, Mathieu, Rousseau, Cyril, Sanna, Alice, de Waard, Jacobus, Tardieu, Laurène, Lekieffre, Maud, Cossard, Yann, Djossou, Félix, de Thoisy, Benoit, Blanchet, Denis, Rousset, Dominique, Kallel, Hatem, Pujo, Jean, and Epelboin, Loïc

Published
2023
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3. Novel Chronic Anaplasmosis in Splenectomized Patient, Amazon Rainforest

Author

Duron, Olivier, Koual, Rachid, Musset, Lise, Buysse, Marie, Lambert, Yann, Jaulhac, Benoit, Blanchet, Denis, Alsibai, Kinan Drak, Lazrek, Yassamine, Epelboin, Loic, Deshuillers, Pierre, Michaud, Celine, and Douine, Maylis

Subjects
Anaplasmosis -- Diagnosis -- Risk factors -- Demographic aspects, Splenectomy -- Patient outcomes, Health
Abstract

Anaplasmoses are emerging tickborne zoonoses caused by intracellular bacteria of the Anaplasma genus. In total, 8 Anaplasma species and several candidate species have been described, including at least 5 species [...]

Published
2022
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4. Breakthrough Infections of SARS-CoV-2 Gamma Variant in Fully Vaccinated Gold Miners, French Guiana, 2021

Author

Vignier, Nicolas, Berot, Vincent, Bonnave, Nathalie, Peugny, Sandrine, Ballet, Mathilde, Jacoud, Estelle, Michaud, Celine, Gaillet, Melanie, Djossou, Felix, Blanchet, Denis, Lavergne, Anne, Demar, Magalie, Nacher, Mathieu, Rousset, Dominique, and Epelboin, Loic

Subjects
Gold miners -- Health aspects -- Genetic aspects, Genetic variation -- Health aspects, Health
Abstract

On May 31, 2021, a gold miner tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the Cacao health center, French Guiana. He worked in a legal gold [...]

Published
2021
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6. Molecular epidemiology of Candida africana isolates collected from vagina swabs in French Guiana.

Author

Bigot, Jeanne, Kalboussi, Yasmine, Bonkoto Nkoy, Yannick, Benmostefa, Alexis, Vellaissamy, Sandra, Benzerara, Laurent, Sainte-Rose, Vincent, Blanchet, Denis, Demar, Magalie, Guitard, Juliette, and Hennequin, Christophe

Abstract

Previous molecular studies have shown that Candida africana corresponds to the clade 13 of Candia albicans. It has been mostly involved in vulvovaginal candidiasis worldwide but few data exist in South America. The aim of our study was to investigate the prevalence of C. africana in women living in French Guiana. For this, we first set up a fluorescent-intercalating-dye-real time Polymerase Chain Reaction (PCR) targeting the hyphal wall protein 1 gene. The test was applied to 212 C. albicans isolates collected from May to August 2019 from vaginal swabs, allowing the identification of six women harboring C. africana (eight isolates). The in vitro susceptibility of these eight isolates to six antifungal drugs was also evaluated. No demographics or clinical-specific features could be demonstrated. Genetic diversity of those isolates was analyzed through multilocus sequence typing and showed that diploid sequence type 182 was predominant (n  = 6) and allowed the report of a new diploid sequence type. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Morphological and Molecular Characterizations of Cochliomyia hominivorax (Diptera: Calliphoridae) Larvae Responsible for Wound Myiasis in French Guiana

Author

Akhoundi, Mohammad, primary, Mathieu, Alexandre, additional, Hannachi, Wajih, additional, Nasrallah, Jade, additional, Quezel, Guillaume, additional, Blaizot, Romain, additional, Blanchet, Denis, additional, Ben Romdhane, Habib, additional, Epelboin, Loïc, additional, and Izri, Arezki, additional

Published
2023
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8. Case Report: Acute Brucellosis Due to Brucella suis in a Brazilian Gold Miner Diagnosed in French Guiana

Author

Melzani, Alessia, primary, Boutrou, Mathilde, additional, Sainte-Rose, Vincent, additional, About, Frédégonde, additional, Douine, Maylis, additional, Michaud, Céline, additional, Nacher, Mathieu, additional, Gaillet, Mélanie, additional, Blanchet, Denis, additional, Lavigne, Jean Philippe, additional, Demar, Magalie, additional, O’Callaghan, David, additional, Djossou, Felix, additional, Keriel, Anne, additional, and Epelboin, Loïc, additional

Published
2023
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12. Angiostrongylus cantonensis Infection of Central Nervous System, Guiana Shield

Author

Defo, Antoine L., Lachaume, Noemie, Cuadro-Alvarez, Emma, Maniassom, Chimene, Martin, Elise, Njuieyon, Falucar, Henaff, Fanny, Mrsic, Yajaira, Brunelin, Annabelle, Epelboin, Loic, Blanchet, Denis, Harrois, Dorothee, Desbois-Nogard, Nicole, Qvarnstrom, Yvonne, Demar, Magalie, Dard, Celine, and Elenga, Narcisse

Subjects
Meningitis -- Health aspects, Cratons -- Health aspects, Health
Abstract

In September 2017, a previously healthy 10-year-old boy from Brazil came to the emergency department of Andree Rosemon Hospital in Cayenne, French Guiana, a French territory that forms the Guiana [...]

Published
2018
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15. Dynamics of SARS-CoV-2 lineages in French Guiana in 2020–2021: 4 epidemic waves with cross-influences from Europe and South America

Author

Miliu, Alexandra, primary, Lavergne, Anne, additional, Succo, Tiphanie, additional, Laizé, Claire, additional, Andrieu, Audrey, additional, Enfissi, Antoine, additional, Enouf, Vincent, additional, Van der Werf, Sylvie, additional, Blanchet, Denis, additional, Demar, Magalie, additional, Carod, Jean-François, additional, Carage, Thierry, additional, Flamand, Claude, additional, Tirera, Sourakhata, additional, Simon-Lorière, Etienne, additional, Rousseau, Cyril, additional, and Rousset, Dominique, additional

Published
2022
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16. First serological evidence of Q fever circulation in ruminant herds in French Guiana

Author

Saout, Mona, Lurier, T., Epelboin, Loïc, Beaudrimont, Xavier, Laghoe, Laure, Blanchet, Denis, Rousset, Elodie, Demar, Magalie, Biome Tropical et Immuno-Pathophysiologie = Tropical Biome and ImmunoPhysiopathology [Lille] (TBIP), Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS)-Université de Guyane (UG), Unité Mixte de Recherche d'Épidémiologie des maladies Animales et zoonotiques (UMR EPIA), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité des Maladies Infectieuses et Tropicales (UMIT), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), Unité Santé et protection animales et végétales environnement Direction de l’environnement, de l’agriculture, de l’alimentation et de la forêt (DEAAF), Laboratoire Hospitalo-Universitaire de Parasitologie-Mycologie, Coordination Régionale de la lutte contre le Virus de L'Immunodéficience Humaine (COREVIH)-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française]-Université des Antilles (UA), Laboratoire de Sophia Antipolis, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), and ROUSSET, Elodie

Subjects
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Abstract

International audience

Published
2022

19. Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018)

Author

Bretagne, Stéphane, Sitbon, Karine, Desnos-Ollivier, Marie, Garcia-Hermoso, Dea, Letscher-Bru, Valérie, Cassaing, Sophie, Millon, Laurence, Morio, Florent, Gangneux, Jean-Pierre, Hasseine, Lilia, Favennec, Loïc, Cateau, Estelle, Bailly, Eric, Moniot, Maxime, Bonhomme, Julie, Desbois-Nogard, Nicole, Chouaki, Taieb, Paugam, André, Bouteille, Bernard, Pihet, Marc, Dalle, Frédéric, Eloy, Odile, Sasso, Milène, Demar, Magalie, Mariani-Kurkdjian, Patricia, Robert, Vincent, Lortholary, Olivier, Dromer, Françoise, French Mycoses Study Group, The, Damiani, Céline, Dupont, Hervé, Maizel, Julien, Totet, Anne, Bouchara, Jean-Philippe, Bellanger, Anne Pauline, Berceanu, Ana, Navellou, Jean Christophe, Scherer, Emeline, Abboud, Philippe, Aznar, Christine, Blanchet, Denis, Djossou, Félix, Cayot, Sophie, Garrouste, Cyril, Lesens, Olivier, Moluçon, Cécile, Nourrisson, Céline, Poirier, Philippe, Bailly, Éloïse, Basmaciyan, Louise, Belaid, Bouhemad, Blot, Mathieu, Caillot, Denis, Charles, Pierre-Emmanuel, Quenot, Jean Pierre, Amazan, Emmanuelle, Baubion, Emilie, Cabie, André, Chabartier, Cyrille, Deligny, Christophe, Emal, Violaine, Flechelle, Olivier, Hatchuel, Yves, Le Govic, Yohann, Merle, Harold, Miossec, Charline, Turmel, Jean-Marie, Valentino, Ruddy, Durieux, Marie-Fleur, Turlure, Pascal, Mercier, Victor, Gari-Toussaint, Martine, Risso, Karine, Simon, Loïc, Bretonnière, Cedric, Boutoille, David, Gastinne, Thomas, Lakhal, Karim, Launay, Elise, Lepoivre, Thierry, Peterlin, Pierre, Rialland, Fanny, Le Pape, Patrice, Canoui, Etienne, Dahane, Naima, Kerneis, Solène, Angebault, Cécile, Bougnoux, Marie-Elisabethh, Guennouni, Nadia, Lanternier, Fanny, Neven, Bennedicte, Oualha, Mehdi, Scemla, Anne, Sitterlé, Emilie, Suarez, Felipe, Toubiana, Julie, Bonacorci, Stéphane, Alanio, Alexandre, Bergeron, Anne, Denis, Blandine, Gits-Muselli, Maud, Hamane, Samia, Touratier, Sophie, Chaumeil, Christine, Merabet, Lilia, Claudéon, Joelle, Curlier, Elodie, Galantine, Valérie, Gallois, Jean Claude, Markowicz, Samuel, Nicolas, Muriel, Musson, Pascal, Schepers, Kinda, Minoza, Alida, Kauffmann-Lacroix, Catherine, Guégan, Hélène, Costa, Damien, Dehais, Marion, Gargala, Gilles, Bajolet, Odile, Banisadr, Firouze, Cousson, Joel, Himberlin, Chantal, Huguenin, Antoine, Toubas, Dominique, Flori, Pierre, Mahinc, Caroline, Raberin, Hélène, Denis, Julie, Herbrecht, Raoul, Mertes, Paul-Michel, Meziani, Fehrat, Sabou, Marcela, Schneider, Francis, Bertozzi, Anne-Isabelle, Chauvin, Pamela, Charpentier, Elena, Cointault, Olivier, Cottrel, Claire, Delavigne, Karen, Faguer, Stanislas, Fillaux, Judith, Guemas, Emilie, Iriart, Xavier, Lelièvre, Lucie, Ruiz, Jean, Bastides, Frédéric, Chesnay, Adélaïde, Desoubeaux, Guillaume, Therby, Audrey, Chachaty, Elisabeth, Gachot, Bertrand, Westerdijk Fungal Biodiversity Institute, Westerdijk Fungal Biodiversity Institute - Software and Databasing, Mycologie moléculaire - Molecular Mycology, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre National de Référence Mycoses Invasives et Antifongiques - National Reference Center Invasive Mycoses & Antifungals (CNRMA), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Dynamique des interactions hôte pathogène (DIHP), Université de Strasbourg (UNISTRA), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Laboratoire Chrono-environnement (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Nantes Université (Nantes Univ), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre Hospitalier Universitaire de Nice (CHU Nice), CHU Rouen, Normandie Université (NU), Centre hospitalier universitaire de Poitiers (CHU Poitiers), Ecologie et biologie des interactions (EBI), Université de Poitiers-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Clermont-Ferrand, CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN), CHU de la Martinique [Fort de France], CHU Amiens-Picardie, Hôpital Cochin [AP-HP], CHU Limoges, SFR UA 4208 Interactions Cellulaires et Applications Thérapeutiques (ICAT), Université d'Angers (UA), Laboratoire de Parasitologie-Mycologie (CHU d'Angers), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Infections Respiratoires Fongiques (IRF), Université d'Angers (UA)-Université de Brest (UBO), Procédés Alimentaires et Microbiologiques [Dijon] (PAM), Université de Bourgogne (UB)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre Hospitalier de Versailles André Mignot (CHV), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Hôpital Robert Debré Paris, Hôpital Robert Debré, Westerdijk Fungal Biodiversity Institute [Utrecht] (WI), Royal Netherlands Academy of Arts and Sciences (KNAW), Service des Maladies infectieuses et tropicales [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 (AGIR ), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Simplification des soins chez les patients complexes - UR UPJV 7518 (SSPC), Université de Picardie Jules Verne (UPJV), Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Laboratoire de Parasitologie-Mycologie [CHU Angers], Hôpital Bretonneau, Centre d’Etude des Pathologies Respiratoires (CEPR), UMR 1100 (CEPR), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by recurrent financial support from Santé Publique France and Institut Pasteur. The funders had no role in study design, data collection, analysis, interpretation of data, or the decision to submit the work for publication., We thank Didier Che (Direction des Maladies Infectieuses, Santé Publique France) for his continuous support and interest in invasive fungal infections and Etienne Sevin (EpiConcept, Paris, France) for his contribution in the development of the RESSIF website using the VOOZANOO platform. We are thankful for the technical help of Catherine Blanc, Anne Boullié, Cécile Gautier, Virginie Geolier, and Damien Hoinard (Institut Pasteur) for the characterization of the isolates received at the NRCMA., The French Mycoses Study Group includes collaborators who contributed to these data by their involvement in the management of patients, expertise in diagnostic tools, and/or characterization of fungal isolates. They are listed in alphabetical order of a city in France and for each center, in alphabetical order of the last names: in Amiens, Céline Damiani, Hervé Dupont, Julien Maizel, and Anne Totet, in Angers, Jean-Philippe Bouchara, in Besançon, Anne Pauline Bellanger, Ana Berceanu, Jean Christophe Navellou, and Emeline Scherer, in Cayenne, Philippe Abboud, Christine Aznar, Denis Blanchet, and Félix Djossou, in Clermont-Ferrand, Sophie Cayot, Cyril Garrouste, Olivier Lesens, Cécile Moluçon, Céline Nourrisson, and Philippe Poirier, in Dijon, Éloïse Bailly, Louise Basmaciyan, Bouhemad Belaid, Mathieu Blot, Denis Caillot, Pierre-Emmanuel Charles, and Jean Pierre Quenot, in Fort de France, Emmanuelle Amazan, Emilie Baubion, André Cabie, Cyrille Chabartier, Christophe Deligny, Violaine Emal, Olivier Flechelle, Yves Hatchuel, Yohann Le Govic, Harold Merle, Charline Miossec, Jean-Marie Turmel, and Ruddy Valentino, in Limoges, Marie-Fleur Durieux and Pascal Turlure, in Nîmes, Victor Mercier, in Nice, Martine Gari-Toussaint, Karine Risso, and Loïc Simon, in Nantes, Cedric Bretonnière, David Boutoille, Thomas Gastinne, Karim Lakhal, Elise Launay, Thierry Lepoivre, Pierre Peterlin, Fanny Rialland, and Patrice Le Pape, in Paris, in Hôpital Cochin, Etienne Canoui, Naima Dahane, and Solène Kerneis, in Hôpital Necker-Enfants Malades, Cécile Angebault, Marie-Elisabethh Bougnoux, Nadia Guennouni, Fanny Lanternier, Bennedicte Neven, Mehdi Oualha, Anne Scemla, Emilie Sitterlé, Felipe Suarez, and Julie Toubiana, in Hôpital Robert-Debré, Stéphane Bonacorci, in Hôpital Saint-Louis, Alexandre Alanio, Anne Bergeron, Blandine Denis, Maud Gits-Muselli, Samia Hamane, and Sophie Touratier, in hôpital des XV-XX, Christine Chaumeil and Lilia Merabet, in Pointe-à-Pitre, Joelle Claudéon, Elodie Curlier, Valérie Galantine, Jean Claude Gallois, Samuel Markowicz, Muriel Nicolas, Pascal Musson, and Kinda Schepers, in Poitiers, Alida Minoza and Catherine Kauffmann-Lacroix, in Rennes, Hélène Guégan, in Rouen, Damien Costa, Marion Dehais, and Gilles Gargala, in Reims, Odile Bajolet, Firouze Banisadr, Joel Cousson, Chantal Himberlin, Antoine Huguenin, and Dominique Toubas, in Saint Etienne, Pierre Flori, Caroline Mahinc, and Hélène Raberin, in Strabourg, Julie Denis, Raoul Herbrecht, Paul-Michel Mertes, Fehrat Meziani, Marcela Sabou, and Francis Schneider, in Toulouse, Anne-Isabelle Bertozzi, Pamela Chauvin, Elena Charpentier, Olivier Cointault, Claire Cottrel, Karen Delavigne, Stanislas Faguer, Judith Fillaux, Emilie Guemas, Xavier Iriart, Lucie Lelièvre, and Jean Ruiz, in Tours, Frédéric Bastides, Adélaïde Chesnay, and Guillaume Desoubeaux, in Versailles, Audrey Therby, and in Villejuif, Elisabeth Chachaty and Bertrand Gachot., and CLEMENT, Nathalie

Subjects
Antifungal Agents, pneumocytosis, invasive fungal infections, Pneumonia, Pneumocystis, [SDV]Life Sciences [q-bio], candidemia, Microbiology, [SDV.MP.MYC] Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, mucormycosis, [SDV] Life Sciences [q-bio], [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Virology, Humans, aspergillosis, epidemiology, Watchful Waiting, Fungemia, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, [SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology, Aged
Abstract

International audience; The French National Reference Center for Invasive Mycoses and Antifungals leads an active and sustained nationwide surveillance program on probable and proven invasive fungal diseases (IFDs) to determine their epidemiology in France. Between 2012 and 2018, a total of 10,886 IFDs were recorded. The incidence increased slightly over time (2.16 to 2.36/10,000 hospitalization days, P = 0.0562) in relation with an increase of fungemia incidence (1.03 to 1.19/10,000, P = 0.0023), while that of other IFDs remained stable. The proportion of ≥65-year-old patients increased from 38.4% to 45.3% (P < 0.0001). Yeast fungemia (n = 5,444) was due mainly to Candida albicans (55.6%) with stable proportions of species over time. Echinocandins became the main drug prescribed (46.7% to 61.8%), but global mortality rate remained unchanged (36.3% at 1 month). Pneumocystis jirovecii pneumonia (n = 2,106) was diagnosed mostly in HIV-negative patients (80.7%) with a significantly higher mortality than in HIV-positive patients (21.9% versus 5.4% at 1 month, P < 0.0001). Invasive aspergillosis (n = 1,661) and mucormycosis (n = 314) were diagnosed mostly in hematology (>60% of the cases) with a global mortality rate of 42.5% and 59.3%, respectively, at 3 months and significant changes in diagnosis procedure over time. More concurrent infections were also diagnosed over time (from 5.4% to 9.4% for mold IFDs, P = 0.0115). In conclusion, we observed an aging of patients with IFD with a significant increase in incidence only for yeast fungemia, a trend toward more concurrent infections, which raises diagnostic and therapeutic issues. Overall, global survival associated with IFDs has not improved despite updated guidelines and new diagnostic tools.IMPORTANCE The epidemiology of invasive fungal diseases (IFDs) is hard to delineate given the difficulties in ascertaining the diagnosis that is often based on the confrontation of clinical and microbiological criteria. The present report underlines the interest of active surveillance involving mycologists and clinicians to describe the global incidence and that of the main IFDs. Globally, although the incidence of Pneumocystis pneumonia, invasive aspergillosis, and mucormycosis remained stable over the study period (2012 to 2018), that of yeast fungemia increased slightly. We also show here that IFDs seem to affect older people more frequently. The most worrisome observation is the lack of improvement in the global survival rate associated with IFDs despite the increasing use of more sensitive diagnostic tools, the availability of new antifungal drugs very active in clinical trials, and a still low/marginal rate of acquired in vitro resistance in France. Therefore, other tracks of improvement should be investigated actively.

Published
2022

20. Case Report: Invasive Cryptococcosis in French Guiana: Immune and Genetic Investigation in Six Non-HIV Patients

Author

Goupil de Bouillé, Jeanne, primary, Epelboin, Loïc, additional, Henaff, Fanny, additional, Migaud, Mélanie, additional, Abboud, Philippe, additional, Blanchet, Denis, additional, Aznar, Christine, additional, Djossou, Felix, additional, Lortholary, Olivier, additional, Elenga, Narcisse, additional, Puel, Anne, additional, Lanternier, Fanny, additional, and Demar, Magalie, additional

Published
2022
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23. Cryptosporidiosis outbreak in Amazonia, French Guiana, 2018

Author

Menu, Estelle, primary, Mosnier, Emilie, additional, Cotrel, Arnaud, additional, Favennec, Loic, additional, Razakandrainibe, Romy, additional, Valot, Stéphane, additional, Blanchet, Denis, additional, Dalle, Frédéric, additional, Costa, Damien, additional, Gaillet, Mélanie, additional, Demar, Magalie, additional, and de Laval, Franck, additional

Published
2022
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26. Trypanosoma cruzi I genotypes in different geographical regions and transmission cycles based on a microsatellite motif of the intergenic spacer of spliced-leader genes

Author

Cura, Carolina I., Mejía-Jaramillo, Ana M., Duffy, Tomás, Burgos, Juan M., Rodriguero, Marcela, Cardinal, Marta V., Kjos, Sonia, Gurgel-Gonçalves, Rodrigo, Blanchet, Denis, De Pablos, Luis M., Tomasini, Nicolás, da Silva, Alexandre, Russomando, Graciela, Cuba, Cesar A. Cuba, Aznar, Christine, Abate, Teresa, Levin, Mariano J., Osuna, Antonio, Gürtler, Ricardo E., Diosque, Patricio, Solari, Aldo, Triana-Chávez, Omar, and Schijman, Alejandro G.

Published
2010
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27. Diagnostic accuracy and acceptability of molecular diagnosis of COVID-19 on saliva samples relative to nasopharyngeal swabs in tropical hospital and extra-hospital contexts: The COVISAL study

Author

Nacher, Mathieu, primary, Mergeay-Fabre, Mayka, additional, Blanchet, Denis, additional, Benois, Orelie, additional, Pozl, Tristan, additional, Mesphoule, Pauline, additional, Sainte-Rose, Vincent, additional, Vialette, Véronique, additional, Toulet, Bruno, additional, Moua, Aurélie, additional, Saout, Mona, additional, Simon, Stéphane, additional, Guidarelli, Manon, additional, Galindo, Muriel, additional, Biche, Barbara, additional, Faurous, William, additional, Chaizemartin, Laurie, additional, Fahrasmane, Aniza, additional, Rochemont, Devi, additional, Diop, Fode, additional, Niang, Moussa, additional, Pujo, Jean, additional, Vignier, Nicolas, additional, Dotou, Dominique, additional, Vabret, Astrid, additional, and Demar, Magalie, additional

Published
2021
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28. Review of diagnostic methods and results for HIV‐associated disseminated histoplasmosis: pathologists are not sufficiently involved

Author

Nacher, Mathieu, primary, Valdes, Audrey, additional, Adenis, Antoine, additional, Blaizot, Romain, additional, Ugo, Françoise, additional, Abboud, Philippe, additional, Demar, Magalie, additional, Djossou, Félix, additional, Epelboin, Loïc, additional, Misslin, Caroline, additional, Blanchet, Denis, additional, Couppié, Pierre, additional, and Drak Alsibai, Kinan, additional

Published
2021
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30. Histoplasmosis of the Central Nervous System: A Case Series between 1990 and 2019 in French Guiana

Author

Epelboin, Loïc, primary, Dione, Aïda, additional, Serris, Alexandra, additional, Blanchet, Denis, additional, Bidaud, Bastien, additional, Walter, Gaëlle, additional, Abboud, Philippe, additional, Mosnier, Emilie, additional, Gaillet, Mélanie, additional, Michaud, Céline, additional, Couppié, Pierre, additional, Demar, Magalie, additional, Nacher, Mathieu, additional, Djossou, Félix, additional, and Adenis, Antoine, additional

Published
2021
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32. Etude rétrospective de la fréquence des infections sexuellement transmissibles à chlamydia et gonocoque chez les patientes du centre de santé de Maripasoula en 2019 et recherche de facteurs associés

Author

Etcheverry, Camille, Carbunar, Aurel, Blanchet, Denis, Gaillet, Mélanie, Thomas, Nadia, Boudon, Thibault, Kiewsky, Valérie, Michaud, Céline, Matillon, Mirlène, and Université de Guyane (UG)

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2021

36. Invasive Fungal Infections in Persons Living with HIV in an Amazonian Context: French Guiana, 2009–2019

Author

Cachera, Laurène, primary, Adenis, Antoine, additional, Guarmit, Basma, additional, Rabier, Sébastien, additional, Couppié, Pierre, additional, Djossou, Felix, additional, Epelboin, Loïc, additional, Melzani, Alessia, additional, Abboud, Philippe, additional, Blanchet, Denis, additional, Demar, Magalie, additional, Alsibai, Kinan Drak, additional, and Nacher, Mathieu, additional

Published
2021
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38. HIV-Associated Disseminated Histoplasmosis and Rare Adrenal Involvement: Evidence of Absence or Absence of Evidence

Author

Nacher, Mathieu, primary, Alsibai, Kinan Drak, additional, Valdes, Audrey, additional, Abboud, Philippe, additional, Adenis, Antoine, additional, Blaizot, Romain, additional, Blanchet, Denis, additional, Demar, Magalie, additional, Djossou, Félix, additional, Epelboin, Loïc, additional, Misslin, Caroline, additional, Ntab, Balthazar, additional, Sabbah, Nadia, additional, and Couppié, Pierre, additional

Published
2021
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39. Prospective Comparison of Saliva and Nasopharyngeal Swab Sampling for Mass Screening for COVID-19

Author

Nacher, Mathieu, primary, Mergeay-Fabre, Mayka, additional, Blanchet, Denis, additional, Benoit, Orelie, additional, Pozl, Tristan, additional, Mesphoule, Pauline, additional, Sainte-Rose, Vincent, additional, Vialette, Véronique, additional, Toulet, Bruno, additional, Moua, Aurélie, additional, Saout, Mona, additional, Simon, Stéphane, additional, Guidarelli, Manon, additional, Galindo, Muriel, additional, Biche, Barbara, additional, Faurous, William, additional, Chaizemartin, Laurie, additional, Fahrasmane, Aniza, additional, Rochemont, Devi, additional, Vignier, Nicolas, additional, Vabret, Astrid, additional, and Demar, Magalie, additional

Published
2021
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42. Epidémie de toxoplasmose amazonienne en territoire amérindien : analyse d'une situation d'émergence

Author

Blaizot, Romain, Nabet, Cécile, Laghoe, L., Faivre, B., Escotte-Binet, Sandie, Djossou, Félix, Mosnier, Emilie, Henaff, Fanny, Blanchet, Denis, Mercier, Aurélien, Dardé, Marie-Laure, Villena, Isabelle, Demar, Magalie Pierre, Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), Protozooses Transmises par l'Alimentation (Cryptosporidiose, Giardose et Toxoplasmose) : Mode de Contamination et Pathogénie (PROTAL) - EA 3800 (PROTAL), Université de Reims Champagne-Ardenne (URCA)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV)-Université de Reims Champagne-Ardenne (URCA)-Université de Picardie Jules Verne (UPJV), Unité des Maladies Infectieuses et Tropicales (UMIT), Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Epidémiologie des parasitoses et mycoses tropicales, Université des Antilles et de la Guyane (UAG)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Parasitologie Mycologie [CHU Limoges], CHU Limoges, Neuroépidémiologie Tropicale (NET), CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Epidémiosurveillance de protozooses à transmission alimentaire et vectorielle (ESCAPE), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Université de Rouen Normandie (UNIROUEN), and Normandie Université (NU)-Normandie Université (NU)-Université de Reims Champagne-Ardenne (URCA)

Subjects
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

43. Émergence de l’angiostrongylose dans les Départements Français d’Amérique (DFA) : étude environnementale autour des gastéropodes

Author

Dard, C., Harrois, Dorothée, Vireeye, N., Miossec, C., Epelboin, Loïc, Nicolas, M., Blanchet, Denis, Aubert, L., Guyomard, S., Demar, Magalie Pierre, Talarmin, A., Desbois-Nogard, Nicole, Centre Hospitalier de Basse-Terre, Unité des Maladies Infectieuses et Tropicales [Cayenne, Guyane Française], Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Université de Guyane (UG), Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), Unité des Maladies Infectieuses et Tropicales (UMIT), Laboratoire de Microbiologie, CHU Pointe-à-Pitre/Abymes [Guadeloupe], and Matillon, Mirlène

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

44. Efficacité de deux posologies de primaquine en prévention des reviviscences de Plasmodium falciparum

Author

Valdes, A., Epelboin, Loïc, Walter, G., Vesin, Guillaume, Abboud, Philippe, Blanchet, Denis, Rémi, Y.P., Demar, Magalie Pierre, Djossou, Félix, Unité des Maladies Infectieuses et Tropicales [Cayenne, Guyane Française], Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Université de Guyane (UG), Unité des Maladies Infectieuses et Tropicales [Cayenne, Guyanne Française], Unité des Maladies Infectieuses et Tropicales (UMIT), Ecosystemes Amazoniens et Pathologie Tropicale (EPat), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Guyane (UG), and Matillon, Mirlène

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2020

47. A Review of Diagnostic Methods and Results for HIV-associated Disseminated Histoplasmosis: Shouldn’t We be Involving Pathologists More Systematically?

Author

Nacher, Mathieu, primary, Valdes, Audrey, additional, Adenis, Antoine, additional, Abboud, Philippe, additional, Demar, Magalie, additional, Djossou, Felix, additional, Epelboin, Loic, additional, Misslin, Caroline, additional, Blanchet, Denis, additional, Couppie, Pierre, additional, and Alsibai, Kinan Drak, additional

Published
2020
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48. Temporal trends of cutaneo-mucous histoplasmosis in persons living with HIV in French Guiana: Early diagnosis defuses South American strain dermotropism

Author

Morote, Sophie, primary, Nacher, Mathieu, additional, Blaizot, Romain, additional, Ntab, Balthazar, additional, Blanchet, Denis, additional, Drak Alsibai, Kinan, additional, Demar, Magalie, additional, Djossou, Félix, additional, Couppié, Pierre, additional, and Adenis, Antoine, additional

Published
2020
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50. Evidence for interfacial uptake in hexadecane degradation by Rhodococcus equi: the importance of cell flocculation

Author

Bouchez-Naitali, Murielle, Blanchet, Denis, Bardin, Veronique, and Vandecasteele, Jean-Paul

Subjects
Bacteria -- Physiological aspects, Alkanes -- Physiological aspects, Hydrocarbons -- Biodegradation, Microbial metabolism -- Research, Biological sciences
Abstract

Rhodococcus equi strains, deficient in biosurfactant formation, take up C(sub)16 alkanes by direct interfacial uptake during their growth on long-chain alkanes as revealed by the degradation kinetics of C(sub)16 alkanes.

Published
2001

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