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Introduction Female workers in textile and metal industry are exposed to various physical and chemical hazards that can lead to the occurrence of gynaecological diseases. Objective The aim of this study was to estimate the frequency of gynaecological diseases among workers of textile and metal industries. METHOD The investigation comprised 197 female workers, 148 from textile and 49 from metal industry, aged from 26 to 57 years. All subjects were hospitalized based on non-gynaecological diagnoses. Gynaecological diagnoses included: tumours of the genital organs and breasts, cervical ectopy and lacerations, inflammatory diseases, disturbances of static of genital organs, cysts, and irregularities of menstrual cycle. Results Textile workers were significantly younger than metal workers, but the groups were comparable according to total and exposure work-time, qualifications and diagnosis on hospital admission. Gynaecological diseases were diagnosed among all investigated subjects. About 80% were diagnosed with tumours and inflammatory diseases. A highly statistically significant difference was observed among groups according to the presence of cervical ectopy and lacerations, which were more frequent among textile workers. Conclusion Comparison of gynaecological status of workers revealed that, among textile workers, cervical ectopy and lacerations were more frequent than among workers in metal industry. .

Introduction. Work in pharmaceutical-chemical industry is characterized by exposure to numerous hazards, both physical (microclimate, illumination, noise) and chemical (organic solvents). Organic solvents can cause damage to many organic systems and have carcinogenic, teratogenic and mutagenic effects. Objective. The aim of this study was to analyze patterns of chronic morbidity of workers employed in pharmaceuticalchemical industry during 2002. Method. The study was conducted in the pharmaceutical- chemical industry "Zdravlje" Leskovac in 2002. A total of 143 workers in workplaces with special working conditions - exposed to chemical hazards as well as 40 workers from control group took part in the study. The physical examinations of the participants were performed at the Department of Occupational Health in Health Center, Leskovac. Results. Heart diseases were the most frequent both among exposed workers (17.8%) and in control group (33.3%). Respiratory diseases were at the second place (16.9% in the exposed group, and 7.4% in control group). Arterial hypertension was diagnosed in 14.7% workers occupationally exposed to hazards, and in 12.5% workers from control group (p>0.05). Chronic bronchitis was diagnosed in 17.5% of the exposed workers and in only 5.0% of controls (p>0.05). The highest prevalence of diseases in both groups was observed among workers aged 40-49 years, with 20-29 years of exposure working time. 73.4% of the exposed workers and 85% of control workers were capable of work (p>0.05). Conclusion. Workers occupationally exposed to hazards in pharmaceutical-chemical industry have higher prevalence of various diseases compared to non-exposed workers, which can be the result of work, working conditions and work activity. Preventive measures should be directed towards the decrease of occupational hazards and unfavorable working conditions and increase of work protection. Regular physical examinations of workers are of prime importance for the prevention of occupational morbidity, traumatism and invalidity. .

In this paper, we test the hypothesis of the Neolithic Demographic Transition in the Central Balkan Early Neolithic (6250-5300 BC) by applying the method of summed calibrated probability distributions to the set of more than 200 new radiocarbon dates from Serbia. The results suggest that there was an increase in population size after the first farmers arrived to the study area around 6250 BC. This increase lasted for approximately 250 years and was followed by a decrease in the population size proxy after 6000 BC, reaching its minimum around 5800 BC. This was followed by another episode of growth until 5600 BC when population size proxy rapidly declined, reaching the minimum again around 5500 BC. The reconstructed intrinsic growth rate value indicates that the first episode of growth might have been fuelled both by high fertility and migrations, potentially related to the effects of the 8.2 ky event. The second episode of population growth after 5800 BC was probably owing to the high fertility alone. It remains unclear what caused the episodes of population decrease. This article is part of the theme issue 'Cross-disciplinary approaches to prehistoric demography'.

Around 8000 years ago, throughout the Neolithic world a new type of artefact appeared, small spoons masterly made from cattle bone, usually interpreted as tools, due to their intensive traces of use. Contrary to those interpretations, the small dimensions of spoons and presence of intensive traces of use led us to the assumption that they were used for feeding babies. In order to test that assumption we compared 2230 marks on three spoons from the Neolithic site of Grad-Starčevo in Serbia (5800-5450 cal BC) with 3151 primary teeth marks produced experimentally. This study has shown that some of the marks on spoons were made by primary teeth, which indicate their usage in feeding babies. The production of a new type of artefact to feed babies is probably related to the appearance of a new type of weaning food, and the abundance of spoons indicates that new baby gruels became an important innovation in prehistoric baby-care., Competing Interests: The authors have declared that no competing interests exist.

The Central Balkans region is of great importance for understanding the spread of the Neolithic in Europe but the Early Neolithic population dynamics of the region is unknown. In this study we apply the method of summed calibrated probability distributions to a set of published radiocarbon dates from the Republic of Serbia in order to reconstruct population dynamics in the Early Neolithic in this part of the Central Balkans. The results indicate that there was a significant population growth after ~6200 calBC, when the Neolithic was introduced into the region, followed by a bust at the end of the Early Neolithic phase (~5400 calBC). These results are broadly consistent with the predictions of the Neolithic Demographic Transition theory and the patterns of population booms and busts detected in other regions of Europe. These results suggest that the cultural process that underlies the patterns observed in Central and Western Europe was also in operation in the Central Balkan Neolithic and that the population increase component of this process can be considered as an important factor for the spread of the Neolithic as envisioned in the demic diffusion hypothesis.

A sequential extraction procedure was applied to identify forms of Ni, Zn, Pb and Cu with Fe- and Mn-oxides associated in alluvial sediments of the River Danube within Pancevo Oil Refinery (Serbia). The five steps of the sequential extraction procedure partitioned metals into: CH(3)COONH(4) extractable (S1); NH(2)OH.HCl carbonate extractable and easily reducible (S2); (NH(4))(2)C(2)O(2)/H(2)C(2)O(2) moderately reducible (S3); H(2)O(2)-HNO(3) organic extractable (S4); and HCl acid soluble residue (S5). Extracted concentrations of trace metals, analyzed after all five steps, were found to be (mg kg(-1)) for Mn: 656, Fe: 26734, Ni: 32.3, Zn: 72.8, Pb: 13.4 and Cu: 27.0. Most of the elements were found in acid soluble residue, characterizing stable compounds in sediments. Non-residual fractions of trace metals (sum of the first four fractions) were analyzed because they are more bioavailable than the residual amount. Correlation analysis and two multivariate analysis methods (principal component and cluster analysis) were used to understand and visualize the associations between the non-residual fractions of trace metals and certain forms, more or less crystalline of Fe- and Mn-oxides within the analyzed sediments, since Fe- and Mn-oxides play an important role in trace metal sorption within aquatic systems, especially within the Danube alluvium where the fluctuations of groundwater are very frequent and the level of groundwater could come close to surface.