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1. An Italian prospective multicenter study on colonoscopy practice and quality: What has changed in the last 10 years

Author

Alvisi, Costanza, Amato, Loretta, Azzurro, Maurizio, Benazzato, Luca, Bianco, Maria Antonia, Biviano, Ivano, Bravi, Ivana, Brunacci, Matteo, Bucci, Cristina, Buonocore, Matteo Rossano, Cadoni, Sergio, Camellini, Lorenzo, Capone, Pietro, Cavallaro, Lucas G., Condino, Giovanna, Crosta, Cristiano, de Bellis, Mario, de Colibus, Patrizia, de Nigris, Francesca, Esposito, Dario, Fiori, Giancarla, Fornasarig, Mara, Fracchia, Mario, Gemme, Carlo, Germanà, Bastianello, Gianni, Elena, Giunta, Mariangela, Guarnieri, Giovanni, Iabichino, Giuseppe, Luigiano, Carmelo, Maiero, Stefania, Marini, Mario, Marone, Pietro, Meucci, Costantino, Morandi, Elisabetta, Mura, Donatella, Nucci, Andrea, Peccianti, Caterina, Praianò, Francesca, Prisco, Antonio, Rastelli, Carlotta, Ravizza, Davide, Rocca, Rodolfo, Rosa, Cesare, Rossi, Giovanni Battista, Sannino, Angela, Testoni, Sabrina, Urban, Flavia, Testoni, Pier Alberto, Notaristefano, Chiara, Soncini, Marco, Hassan, Cesare, Monica, Fabio, Radaelli, Franco, Triossi, Omero, Pasquale, Luigi, Neri, Matteo, Cannizzaro, Renato, and Leandro, Gioacchino

Published
2023
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10. An Italian prospective multicenter study on colonoscopy practice and quality: What has changed in the last 10 years

Author

Testoni, Pier Alberto, primary, Notaristefano, Chiara, additional, Soncini, Marco, additional, Hassan, Cesare, additional, Monica, Fabio, additional, Radaelli, Franco, additional, Triossi, Omero, additional, Pasquale, Luigi, additional, Neri, Matteo, additional, Cannizzaro, Renato, additional, Leandro, Gioacchino, additional, Alvisi, Costanza, additional, Amato, Loretta, additional, Azzurro, Maurizio, additional, Benazzato, Luca, additional, Bianco, Maria Antonia, additional, Biviano, Ivano, additional, Bravi, Ivana, additional, Brunacci, Matteo, additional, Bucci, Cristina, additional, Buonocore, Matteo Rossano, additional, Cadoni, Sergio, additional, Camellini, Lorenzo, additional, Capone, Pietro, additional, Cavallaro, Lucas G., additional, Condino, Giovanna, additional, Crosta, Cristiano, additional, de Bellis, Mario, additional, de Colibus, Patrizia, additional, de Nigris, Francesca, additional, Esposito, Dario, additional, Fiori, Giancarla, additional, Fornasarig, Mara, additional, Fracchia, Mario, additional, Gemme, Carlo, additional, Germanà, Bastianello, additional, Gianni, Elena, additional, Giunta, Mariangela, additional, Guarnieri, Giovanni, additional, Iabichino, Giuseppe, additional, Luigiano, Carmelo, additional, Maiero, Stefania, additional, Marini, Mario, additional, Marone, Pietro, additional, Meucci, Costantino, additional, Morandi, Elisabetta, additional, Mura, Donatella, additional, Nucci, Andrea, additional, Peccianti, Caterina, additional, Praianò, Francesca, additional, Prisco, Antonio, additional, Rastelli, Carlotta, additional, Ravizza, Davide, additional, Rocca, Rodolfo, additional, Rosa, Cesare, additional, Rossi, Giovanni Battista, additional, Sannino, Angela, additional, Testoni, Sabrina, additional, and Urban, Flavia, additional

Published
2023
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14. The Percentage of Signet Ring Cells Is Inversely Related to Aggressive Behavior and Poor Prognosis in Mixed-Type Gastric Cancer

Author

Marano, Luigi, primary, Ambrosio, Maria Raffaella, additional, Resca, Luca, additional, Carbone, Ludovico, additional, Carpineto Samorani, Osvaldo, additional, Petrioli, Roberto, additional, Savelli, Vinno, additional, Costantini, Maurizio, additional, Malaspina, Lara, additional, Polom, Karol, additional, Biviano, Ivano, additional, Marrelli, Daniele, additional, and Roviello, Franco, additional

Published
2022
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16. Signet ring cell percentage in poorly cohesive gastric cancer patients: A potential novel predictor of survival

Author

Roviello, Franco, primary, Marano, Luigi, additional, Ambrosio, Maria Raffaella, additional, Resca, Luca, additional, D'Ignazio, Alessia, additional, Petrelli, Federica, additional, Petrioli, Roberto, additional, Costantini, Maurizio, additional, Polom, Karol, additional, Macchiarelli, Raffaele, additional, Biviano, Ivano, additional, and Marrelli, Daniele, additional

Published
2022
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20. Effect of ambient temperature on daily hospital admissions for acute pancreatitis in Nanchang, China: A time-series analysis.

Author

Li, Bozhen, Huang, Wenzhong, Chen, Pengguo, Chen, Jianyong, Biviano, Ivano, and Wang, Zhaohan

Subjects
HEAT, TEMPERATURE, RISK assessment, TIME series analysis, PANCREATITIS, ACUTE diseases, CLIMATE change, DISEASE risk factors
Abstract

The aim of this study was to evaluate the short-term effect of temperature on the risk of acute pancreatitis (AP) in southern China. We performed a time-series study of 2822 patients admitted with a first episode of AP in Nanchang between May 2014 and June 2017. A generalized additive model combined with a distributed lag non-linear model was applied to assess the association of temperature and AP. In subgroup analysis, according to different etiologies of pancreatitis, significant associations were found between daily average temperature and non-biliary pancreatitis hospitalization at lags of 0–7 days, but not for biliary pancreatitis or total AP. Higher daily average temperature tended to increase the occurrence of non-biliary pancreatitis at lags of 0–7 days. These findings suggest that high temperature is associated with higher non-biliary pancreatitis risk in Nanchang, China. In the context of global warming, the morbidity of non-biliary pancreatitis may increase. [ABSTRACT FROM AUTHOR]

Published
2022
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22. Effectiveness and Safety of Nonmedical Switch From Adalimumab Originator to SB5 Biosimilar in Patients With Inflammatory Bowel Diseases: Twelve-Month Follow-Up From the TABLET Registry

Author

Tapete, Gherardo, primary, Bertani, Lorenzo, additional, Pieraccini, Alberto, additional, Lynch, Erica Nicola, additional, Giannotta, Martina, additional, Morganti, Riccardo, additional, Biviano, Ivano, additional, Naldini, Sara, additional, Mumolo, Maria Gloria, additional, De Nigris, Francesca, additional, Calella, Francesca, additional, Bagnoli, Siro, additional, Minciotti, Moira, additional, Maltinti, Simona, additional, Rentini, Silvia, additional, Ceccarelli, Linda, additional, Lionetti, Paolo, additional, Milla, Monica, additional, and Costa, Francesco, additional

Published
2021
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24. Fecal gluten immunogenic peptides as indicators of dietary compliance in celiac patients

Author

Porcelli, Brunetta, primary, Ferretti, Fabio, additional, Cinci, Francesca, additional, Biviano, Ivano, additional, Santini, Alessia, additional, Grande, Elisabetta, additional, Quagliarella, Francesco, additional, Terzuoli, Lucia, additional, Bacarelli, Maria R., additional, Bizzaro, Nicola, additional, Vascotto, Marina, additional, and Marini, Mario, additional

Published
2020
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29. Effectiveness and Safety of Nonmedical Switch From Adalimumab Originator to SB5 Biosimilar in Patients With Inflammatory Bowel Diseases: Twelve-Month Follow-Up From the TABLET Registry.

Author

Tapete, Gherardo, Bertani, Lorenzo, Pieraccini, Alberto, Lynch, Erica Nicola, Giannotta, Martina, Morganti, Riccardo, Biviano, Ivano, Naldini, Sara, Mumolo, Maria Gloria, Nigris, Francesca De, Calella, Francesca, Bagnoli, Siro, Minciotti, Moira, Maltinti, Simona, Rentini, Silvia, Ceccarelli, Linda, Lionetti, Paolo, Milla, Monica, and Costa, Francesco

Published
2022
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32. Bloating is associated with worse quality of life, treatment satisfaction, and treatment responsiveness among patients with constipation-predominant irritable bowel syndrome and functional constipation

Author

Neri, L., Iovino, P., Altomare, Donato Francesco, Annese, Vito, Badiali, Danilo, Basilisco, Guido, Bassotti, Gabrio, Battaglia, Edda, Bazzocchi, Gabriele, Bellini, Massimo, Bendia, Emanuele, Benini, Luigi, Biscaglia, Giuseppe, Biviano, Ivano, Bocchini, Renato, Bonventre, Sebastiano, Bossa, Fabrizio, Brandimarte, Giovanni, Cannizzaro, Renato, Cicala, Michele, Cipolletta, Livio, Clara, Virgilio, Cogliandro, Rosanna, Comandini, Giulia, Corazziari, Enrico, Crotta, Sergio, Cuomo, Rosario, D'Alba, Lucia, De Giorgi, Francesco, Del Piano, Mario, Di Fonzo, Michela, Di Mario, Francesco, Di Stefano, Michele, D'Onofrio, Vittorio, Efthymakis, Kostantinos, Fiore, Pierluigi, Fortuna, Manuela, Fries, Walter, Gaetani, Eleonora, Galeazzi, Francesca, Gasbarrini, Antonio, Geccherle, Andrea, Giangregorio, Francesco, Girardi, Lisa, Grassini, Mario, Groppo, Marzia, Guarnieri, Giovanni, Lo Cascio, Massimiliano, Lolli, Roberto, Luzza, Francesco, Macarri, Giampiero, Marino, Maria, Miraglia, Stefania, Monastra, Santo, Neri, Maria Cristina, Neri, Matteo, Noris, Roberto Antonio, Orselli, Silvia, Passaretti, Sandro, Paviotti, Alberto, Pazzi, Paolo, Pilotto, Alberto, Portincasa, Piero, Ranaldo, Nunzio, Ravelli, Paolo, Rogai, Francesca, Sablich, Renato, Savarino, Vincenzo, Spinzi, Giancarlo, Stanghellini, Vincenzo, Tammaro, Leonardo, Torresan, Francesco, Usai Satta, Paolo, Valle, C. Claudio, Neri, L., Iovino, P., Altomare, Donato Francesco, Annese, Vito, Badiali, Danilo, Basilisco, Guido, Bassotti, Gabrio, Battaglia, Edda, Bazzocchi, Gabriele, Bellini, Massimo, Bendia, Emanuele, Benini, Luigi, Biscaglia, Giuseppe, Biviano, Ivano, Bocchini, Renato, Bonventre, Sebastiano, Bossa, Fabrizio, Brandimarte, Giovanni, Cannizzaro, Renato, Cicala, Michele, Cipolletta, Livio, Clara, Virgilio, Cogliandro, Rosanna, Comandini, Giulia, Corazziari, Enrico, Crotta, Sergio, Cuomo, Rosario, D'Alba, Lucia, De Giorgi, Francesco, Del Piano, Mario, Di Fonzo, Michela, Di Mario, Francesco, Di Stefano, Michele, D'Onofrio, Vittorio, Efthymakis, Kostantino, Fiore, Pierluigi, Fortuna, Manuela, Fries, Walter, Gaetani, Eleonora, Galeazzi, Francesca, Gasbarrini, Antonio, Geccherle, Andrea, Giangregorio, Francesco, Girardi, Lisa, Grassini, Mario, Groppo, Marzia, Guarnieri, Giovanni, Lo Cascio, Massimiliano, Lolli, Roberto, Luzza, Francesco, Macarri, Giampiero, Marino, Maria, Miraglia, Stefania, Monastra, Santo, Neri, Maria Cristina, Neri, Matteo, Noris, Roberto Antonio, Orselli, Silvia, Passaretti, Sandro, Paviotti, Alberto, Pazzi, Paolo, Pilotto, Alberto, Portincasa, Piero, Ranaldo, Nunzio, Ravelli, Paolo, Rogai, Francesca, Sablich, Renato, Savarino, Vincenzo, Spinzi, Giancarlo, Stanghellini, Vincenzo, Tammaro, Leonardo, Torresan, Francesco, Usai Satta, Paolo, Valle, C. Claudio, Altomare, D., Annese, V., Badiali, D., Basilisco, G., Bassotti, G., Battaglia, E., Bazzocchi, G., Bellini, M., Bendia, E., Benini, L., Biscaglia, G., Biviano, I., Bocchini, R., Bonventre, S., Bossa, F., Brandimarte, G., Cannizzaro, R., Cicala, M., Cipolletta, L., Clara, V., Cogliandro, R., Comandini, G., Corazziari, E., Crotta, S., Cuomo, R., D'Alba, L., De Giorgi, F., Del Piano, M., Di Fonzo, M., Di Mario, F., Di Stefano, M., D'Onofrio, V., Efthymakis, K., Fiore, P., Fortuna, M., Fries, W., Gaetani, E., Galeazzi, F., Gasbarrini, A., Geccherle, A., Giangregorio, F., Girardi, L., Grassini, M., Groppo, M., Guarnieri, G., Lo Cascio, M., Lolli, R., Luzza, F., Macarri, G., Marino, M., Miraglia, S., Monastra, S., Neri, M., Noris, R., Orselli, S., Passaretti, S., Paviotti, A., Pazzi, P., Pilotto, A., Portincasa, P., Ranaldo, N., Ravelli, P., Rogai, F., Sablich, R., Savarino, V., Spinzi, G., Stanghellini, V., Tammaro, L., Torresan, F., Usai Satta, P., and Valle, C.

Subjects
Adult, Male, Quality of life, medicine.medical_specialty, Constipation, Cross-sectional study, Physiology, Bloating, Chronic constipation, Functional constipation, Irritable bowel syndrome, Patient-reported outcomes, Treatment satisfaction, Endocrine and Autonomic Systems, Gastroenterology, Cross-Sectional Studies, Female, Flatulence, Humans, Irritable Bowel Syndrome, Middle Aged, Prevalence, Quality of Life, Surveys and Questionnaires, Endocrine and Autonomic System, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Patient-reported outcome, Settore MED/12 - Gastroenterologia, business.industry, Settore MED/09 - MEDICINA INTERNA, medicine.disease, Settore MED/18 - Chirurgia Generale, Tolerability, 030220 oncology & carcinogenesis, Physical therapy, 030211 gastroenterology & hepatology, medicine.symptom, business
Abstract

Background The management of bloating is unclear and its relationship with patients' well-being and treatment satisfaction independent of other abdominal symptoms is uncharacterized. We evaluated the association of bloating with patient-reported outcomes. Methods Thirty-nine centers for functional gastrointestinal disorders joined the laxative inadequate relief survey. We enrolled 2203 consecutive outpatients with functional constipation (FC) or constipation-predominant irritable bowel syndrome (IBS-C) in two cross-sectional waves. Both wave 1 and 2 included the SF-12, the patient assessment of constipation-symptoms (PAC-SYM), and the treatment satisfaction questionnaire for medication (TSQM-2). Wave 2 only included a global rating of change (GRC) scale to assess patients' assessment of efficacy concerning treatment switches occurred in the 3 months prior to the interview. Bloating in the abdomen was defined on the basis of PAC-SYM item 3. Key Results The average age was 50.1 years (SD, 16.7) and 82.1% of patients were women. The prevalence of bloating was 91.6% (n = 1970). Bloating was associated with SF-12 Physical Composite Score (p < 0.01), SF-12 Mental Composite Score (p < 0.01), GRC (p < 0.01), Satisfaction with treatment effectiveness (p < 0.01), convenience of administration (p < 0.01), and side effects (p < 0.01) after adjustment for possible confounders. Conclusions & Inferences Our data suggest that patients regard bloating as a key element in assessing clinical changes and treatments' efficacy as this symptom exerts a strong influence on patient-reported outcomes independent of possible confounders and other symptoms of constipation. Our data provide the rationale to investigate the efficacy and tolerability of new treatments specifically addressing this important, yet disregarded, patients' complain.

Published
2016

33. Testing for fecal gluten immunogenic peptides: a useful tool to evaluate compliance with gluten-free diet by celiacs.

Author

Porcelli, Brunetta, Ferretti, Fabio, Biviano, Ivano, Santini, Alessia, Cinci, Francesca, Vascotto, Marina, Granded, Elisabetta, Quagliarella, Francesco, Terzuoli, Lucia, Bizzaro, Nicola, Marini, Mario, and Rentini, Silvia

Subjects
GLUTEN-free diet, GLUTEN, PATIENT compliance, PEPTIDES, ANTI-antibodies
Abstract

Background Although experts agree that strict dietary compliance is fundamental for the health of celiac patients, there are no evidence-based recommendations on the best way to assess dietary compliance. Detection of gluten immunogenic peptides (GIPs) in feces was recently proposed as an effective method of assessing the dietary compliance of celiac patients. Methods Fifty-five consecutive celiac patients (27 adults and 28 children, age 6-72 years), who had been on a gluten-free diet for at least 2 years, were enrolled. All patients were evaluated clinically for symptoms, physical parameters and laboratory parameters. Dietary compliance was assessed with the Biagi questionnaire and serum anti-tissue transglutaminase (tTG) IgA antibodies were measured. GIPs were determined by immunoenzymatic assay on an automated Chorus analyzer (DIESSE Diagnostica Senese), after extraction of fecal samples by the method developed by DIESSE. Results Eight patients tested positive for GIPs (GIPs+); 71.4% of GIP-positive patients were asymptomatic; tTG antibodies were detected in 3/8 GIP+ patients. The Biagi score was significantly associated with fecal positivity for GIPs (P=0.02). However, according to the Biagi score, 57.1% of GIP+ patients followed the diet strictly and 5.4% of GIP- subjects did not comply with the diet or made substantial mistakes. Conclusions Assay of fecal GIPs identified more patients who did not comply with the diet than did the Biagi questionnaire, evaluation of symptoms or anti-tTG antibodies. Detection of fecal GIPs offers a direct, objective, quantitative assessment of even occasional exposure to gluten and is confirmed as a practical way to check dietary compliance. [ABSTRACT FROM AUTHOR]

Published
2020
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35. iProcto: new digital technology in Proctology. A randomized study

Author

Gaj, Fabio, Department of General Surgery, Surgical Specialties, Organ Transplantation 'Paride Stefanini', Department of Medicine, Medical Specialties, Policlinico Umberto I., and Biviano, Ivano

Subjects
rectocele, pelvic floor, iProcto, pelvic floor, rectocele, iProcto
Published
2017

40. [Local and late complications in anorectal surgery]

Author

Gaj, Fabio, Candeloro, Laura, and Biviano, Ivano

Subjects
Adult, Male, Complications scoring, Rectocele, Rectum, Anal Canal, proctological disease, quality of life, Middle Aged, Hemorrhoids, Severity of Illness Index, Postoperative Complications, Rectal Diseases, Treatment Outcome, Surveys and Questionnaires, Quality of Life, Humans, Female, Fissure in Ano, Digestive System Surgical Procedures, Aged
Abstract

Our experience in colon-proctology showed the need to update the post-surgical complications score we published (1), adding others that may have an impact on outcome of treatment. The aim of this study was to assess the efficacy of a score obtained from the analysis of the quality of life and severity of complications after proctologic surgery.Between January and December 2013, we studied 150 patients undergoing several ano-rectal surgeries for the presence of hemorrhoids of grade III and IV (63 patients), anal fissures (42 patients), anal fistulas (19 patients), rectocele (15 patients) and mucosal prolapse of the rectum (11 patients). After surgery, patients were evaluated through outpatient visits at 3, 6 and 12 months, by a questionnaire concerning the surgery complications and quality of life, the latter expressed with a score from 0 (poor) to 10 (excellent).Only 134 patients [mean age: 49 years (range 35-61 years), 62 M] completed the entire follow-up. The score of complications has been gradually decreasing from 11.3 (baseline) to 9.6 to 3 months, 3.6 to 6 months and 2.3 at 12 months, while the score of the quality of life progressively increased from 4.5 to 6, 8 and 8.5 respectively (p0.05), with a correlation between the two score (r=-0.6, p= 0.03).The quantification by scores of quality of life and postoperative complications in colon-proctology is an important prognostic predictor.

Published
2015

50. Anal self-massage in the treatment of acute anal fissure: a randomized prospective study.

Author

Gaj, Fabio, Biviano, Ivano, Candeloro, Laura, and Andreuccetti, Jacopo

Subjects
*FISSURE in ano, *ANAL diseases, *SPHINCTERS, *PREVENTION, *THERAPEUTICS
Abstract

Background An anal fissure (AF) is a tear in the epithelial lining of the anal canal. This is a very common condition, but the choice of treatment is unclear. The use of anal dilators is effective, economic, and safe. The aim of the study was to compare the efficacy of two conservative treatments, the use of anal dilators or a finger for anal dilatation, in reducing anal pressure and resolving anal fissures. Methods Fifty patients with a clinical diagnosis of AF were randomly assigned to one of the treatments, self-massage of the anal sphincter (group A, 25 patients) or passive dilatation using dilators (group B, 25 patients). All patients were evaluated at baseline, at the end of treatment, and after 12 weeks and 6 months. Pain was measured using a visual analog scale. Results After the treatment, 60% of patients treated with dilators and 80% of patients treated with anal self-massage using a finger showed disappearance of their anal fissures. A comparison between signs and symptoms reported by the patients in the two groups showed a statistically significant reduction in anal pain (group A, P=0.0001; group B, P=0.0001) and bleeding after defecation (group A, P=0.001, group B, P=0.001). At 6 months after treatment, a significantly greater reduction in anal pain was observed in Group A compared to Group B (P=0.02). Conclusion The use of anal self-massage with a finger appears to induce a better resolution of acute anal fissure than do anal dilators, and in a shorter time. [ABSTRACT FROM AUTHOR]

Published
2017
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