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This study aimed to investigate the ability of both subjective and objective sleep measures to predict balance difficulty in agricultural workers. Seven male farmers from rural Nebraska were analyzed for static balance performance following a bout of sleep. Actiwatches were used to measure objective sleep hours and subjective questionnaires, including the Epworth Sleepiness Scale and the Pittsburgh Sleep Quality Index, were used to measure subjective hours of sleep and sleep quality. The participants were observed for 12 sessions, with six in planting season and six in harvest season. Static balance testing consisted of measuring the area, total displacement, and maximum range in the anteroposterior and mediolateral directions of the individual's center of pressure with Tekscan pressure mats. Overall, it was found that objective measures had a higher correlation with the magnitude of balance deviations than subjective measures. [ABSTRACT FROM AUTHOR]

In Australia, exploitation of shale gas is at an early stage. Western Australia has estimated its technically recoverable gas resources at 235 trillion cubic feet (tcf). It is viewed as an exciting economic prospect and decarbonising option for transition to climate change mitigation. The central focus of this paper is to estimate the climate impacts of Australian shale gas fracking and compare with other energy sources. Electricity generation has been considered as end use of gas in export scenarios to Japan and China. Analysis has been done for resource development periods of 20 and 40 years. Carbon footprints of shale gas range from 604MtCO2e to 543 MtCO2e per annum for China and Japan export cases, respectively, for 20 years field lifetime, if 66 tcf of shale gas is exploited and used. This result is roughly equivalent to 115% of Australia's total national emissions for the year 2014. If all technically recoverable shale gas (235tcf) from the Canning Basin in the Kimberley is exploited and exported to China and Japan over 40 years, the annual emissions are double the total Australian national emissions. The result suggests that shale gas has low carbon intensity compared to coal and oil but solar PV and wind are much cleaner energy options for GHG mitigation. The solar PV and wind electricity would produce 8% and 5% of the shale gas electricity emissions, respectively. Unless accompanied by stringent regulation and compliance on the upstream resource development, stage shale gas cannot be an appropriate energy source for sustainable development as opposed to renewable energy sources.

Biofuel is identified as one of the key renewable energy sources for sustainable development, and can potentially replace fossil-based fuels. Anticipating the competition between food and energy security, the Australian Government is intensively exploring other biofuel resources. There have been numerous research projects in Australia using the second and third generation model based on different feedstocks including lignocellulosic and microalgae. Such projects have been successfully demonstrated but are yet to be commercially viable. Moreover, transition pathways to realize the potential benefits of these value chains are not well understood. This preliminary study tried to provide an alternative framework and proposes future long-term transport biofuel pathways in Australia which can be seen as a solution for a post-carbon society. The study is targeted to outline the milestone of the Australian biofuel industry and its roadmap into the future. An investigation has been carried out on biofuel status and barrier, technology development, market and the chronology of biofuel related policies in Australia to understand the current situation and possibilities to develop further strategies, while also providing an insight into the consequences of producing biofuel for transportation. Several methods have been proposed to introduce the transition into a post-carbon society. Seven scenarios were divided, covering the roadmap of first, second and third generation of biofuel, alternative transportation modes such as electric vehicles (EVs) and fuel cell vehicles (FCVs) and the elimination of the fossil fuel running vehicles within a time frame of 20 years. The utilization of biofuel can be seen as a short to medium mode for transition into a green transportation society. Our investigation also showed that microalgae gave a better ecological footprint which offers the strongest potential for future Australian biofuel industry and aviation. Meanwhile, EVs and FCVs also share the portion for long-term transportation modes scenario.

Western Australia has globally significant onshore gas resources, with over 280 trillion cubic feet of economically recoverable gas located in five shale basins. The Western Australian Government and gas industry have promoted the development of these resources as a “clean energy source” that would “help to reduce global carbon emissions” and provide a “transition fuel” to a low carbon economy. This research examines those claims by reviewing existing literature and published data to estimate the life cycle greenhouse gas (GHG) pollution that would result from the development of Western Australia’s onshore gas basins using hydraulic fracking. Estimates of carbon pollution from each stage in gas development, processing, transport and end-use are considered in order to establish total life-cycle emissions in tonnes of carbon-dioxide equivalent (CO2e). The emissions estimates draw from published research on emissions from shale gas development in other jurisdictions as well as industry or government reported emissions from current technology for gas processing and end-use as applicable. The current policy and regulatory environment for carbon pollution and likely resulting GHG mitigation measures has also been considered, as well as the potential for the gas to displace or substitute for other energy sources. In areas where there is uncertainty, conservative emissions estimates have been used. Modelling of GHG emissions has been undertaken for two comparison resource development and utilisation scenarios; Australian domestic and 100% export i.e. no domestic use. Each scenario corresponds to a different proportionate allocation of emissions accounted for domestic emissions in Australia and emissions accounted for in other jurisdictions. Emissions estimates for the two scenarios are 245–502 MTCO2e/year respectively over a resource development timeframe of 20 years. This is roughly the same as Australia’s total GHG emissions in 2014 which were 525 MTCO2e/year. This research concludes that GHG emissions resulting from the development of Western Australia’s five onshore gas basins would be equivalent to all other Australian emissions sources combined at 2014 levels each year for 20 years which is the general lifetime of a well.

Background: The prevalence of xylazine, a non-opioid tranquilizer not for human consumption, in illicitly manufactured fentanyl is increasing in the United States. However, little is known about xylazine awareness and attitudes among people who use drugs., Methods: A cross-sectional survey of people who use drugs in Ohio was conducted from November 2023 - May 2024 to identify xylazine awareness and attitudes in rural and urban counties across the state. Study participants were recruited from naloxone distribution sites, including health departments, syringe service programs, and community-based organizations., Results: Among 630 people who use drugs in Ohio, more than one-half (53.5%) were unaware of xylazine being in "street drugs," regardless of urbanicity. Among individuals who were aware of xylazine, most (73.0%) indicated they did not want to use the drug and try to avoid it. In addition, 75.8% of this group felt it was "very" or "extremely" important to know if xylazine was in their drugs., Discussion: This research found that many people who use drugs in Ohio are unaware of xylazine and its risks. An important finding of this study is that most individuals who had heard of xylazine did not want to use it and were concerned about knowing whether xylazine was in their drugs., (© 2024. The Author(s).)

Background: Higher educational attainment is important for economic wellbeing and associated with better health and longevity. Previous research focused on intelligence, socioeconomic status and mental health or individual risk behaviours as predictors of educational attainment, but the role of multiple domains of adolescent risk behaviours is less clear. This study examined the association between multiple domains of risk behaviour in adolescence and educational attainment by 22 years-of-age., Methods: Young people (Generation 2, Gen2) and their parents (Generation 1, Gen1) participating in the Raine Study completed questionnaires at years 1, 5, 8, 10 (Gen1 only), 14, 17 (both) and 22 (Gen2 only). The Raine Study is an ongoing longitudinal study initiated in Perth, Western Australia, between 1989 and 1991. The 1,102 Gen2 participants who responded to questions about highest educational attainment were included in this study. The association between Gen2 self-reported risk behaviours (including age at commencement of drinking alcohol, smoking, sexual intercourse and drug use) and educational attainment (defined as self-reported years of completed high school: ≤10, 11, 12 or tertiary education (> 12)) at year 22, after adjusting for mother's age and combined parental education level, participant sex, and family income, educational performance and adolescent mental health, was explored using ordinal regression models and presented as odds ratios (OR) with 95% confidence intervals (CI)., Results: Ordinal models suggested that never smoking or starting older than 18 compared with smoking before age 15 (OR 2.02, 95%CI: 1.28-2.14); first drinking alcohol between 15 and 17 years compared with younger than 15 (OR 1.52, 95%CI: 1.08-2.14); and, first sexual intercourse aged ≥ 18 years compared with under 15 (OR 1.67, 95%CI: 1.08-2.57) were associated with higher levels of educational attainment at 22-year follow-up. Additionally, lower ("better") behavioural scores increased the odds of higher levels of attainment., Conclusions: Absence of health risk behaviours at a younger age or later commencement was associated with higher educational attainment. Evidence-based interventions that address the societal influences underpinning risk behaviours in adolescents may support longer school retention., (© 2024. The Author(s).)

Amyotrophic lateral sclerosis (ALS) is characterised primarily by motor system degeneration, with clinical evidence of cognitive and behavioural change in up to 50% of cases. We have shown previously that resting-state EEG captures dysfunction in motor and cognitive networks in ALS. However, the longitudinal development of these dysfunctional patterns, especially in networks linked with cognitive-behavioural functions, remains unclear. Longitudinal studies on non-motor changes in ALS are essential to further develop our understanding of disease progression, improve care and enhance the evaluation of new treatments. To address this gap, we examined 124 ALS individuals with 128-channel resting-state EEG recordings, categorised by cognitive impairment (ALSci, n = 25), behavioural impairment (ALSbi, n = 58), or non-impaired (ALSncbi, n = 53), with 12 participants meeting the criteria for both ALSci and ALSbi. Using linear mixed-effects models, we characterised the general and phenotype-specific longitudinal changes in brain network, and their association with cognitive performance, behaviour changes, fine motor symptoms, and survival. Our findings revealed a significant decline in [Formula: see text]-band spectral power over time in the temporal region along with increased [Formula: see text]-band power in the fronto-temporal region in the ALS group. ALSncbi participants showed widespread β-band synchrony decrease, while ALSci participants exhibited increased co-modulation correlated with verbal fluency decline. Longitudinal network-level changes were specific of ALS subgroups and correlated with motor, cognitive, and behavioural decline, as well as with survival. Spectral EEG measures can longitudinally track abnormal network patterns, serving as a candidate stratification tool for clinical trials and personalised treatments in ALS., (© 2024. The Author(s).)

Background: The prevalence of low birth weight (LBW) has stagnated at approximately 12% for the past 15 years in Nepal, significantly impacting newborn survival. While antenatal care (ANC) visits and iron-folic acid supplementation are recognised as important interventions to reduce LBW, there is a lack of evidence regarding their combined effect. This study aimed to explore the potential synergistic impact of ANC and iron-folic acid supplementation on LBW in Nepal by analyzing data from two national surveys., Methods: The nationally representative Nepal Demographic and Health Surveys of 2016 and 2022 were used, and the pooled dataset was analysed. Birth weight and the prevalence of LBW (i.e. birthweight < 2500 g) were reported using descriptive statistics. The associations among LBW, ANC visits, and iron-folic acid supplementation were examined using logistic regression analyses., Results: The mean birth weight was 3011 g, with an LBW prevalence of 11.2%. Not attending ANC (Adjusted Odds Ratio (AOR): 1.49; 95% Confidence Interval (CI): 1.14, 1.95) and not consuming iron-folic acid supplements (AOR: 1.43; 95% CI: 1.11, 1.84) were independently associated with a higher likelihood of having LBW. Furthermore, when considering both factors together, mothers who attended less than four ANC visits and consumed iron-folic acid for ≤ 90 days had the higher likelihood of having LBW (AOR: 1.99; 95% CI: 1.35, 2.60) compared to those who did not., Conclusions: This study highlights that the individual and joint influence of ANC visits and iron-folic acid supplementation on having LBW. These findings underscore the significance of ANC attendance and iron-folic acid supplementation in preventing LBW. Traditionally, these two interventions were primarily considered as maternal survival strategies. However, our findings indicate that these existing interventions could be utilised further for both maternal and newborn survival. Given that these services are offered free of cost and are available near people's homes through the National Safe Motherhood Programme in Nepal, efforts to increase the uptake of these services should be strengthened while emphasising their role in preventing LBW., (© 2024. The Author(s).)

Heatwaves pose a serious threat and are projected to amplify with changing climate and social demographics. A comprehensive understanding of heatwave exposure to the communities is imperative for the development of effective strategies and mitigation plans. This study explores spatiotemporal characterization of heatwaves across the historically vulnerable communities in Mississippi, United States. We derive multiple heatwave metrics including frequency, duration, and magnitude based on temperature data for urban-specific daytime, nighttime, and day-night combined conditions. Our analysis depicts a rising heatwave trend across all counties, with the most extreme shifts observed in prolonged day-night events lacking overnight relief. We integrate physical heatwave hazards with a socioeconomic vulnerability index to develop an integrated urban heatwave risk index. Integrated metric identifies the counties in northwest Mississippi as heat-prone areas, exhibiting an urgent need to prioritize heat resilience and adaptive strategies in these regions. The compounding urban heatwave and vulnerability risks in these communities highlights an environmental justice imperative to implement equitable policies that protect disadvantaged populations. Although this study is focused on Mississippi, our framework is scalable and can be employed to urban regions globally. This study provides a solid foundation for developing timely heatwave preparedness and mitigation to avert preventable heat-related tragedies as extremes intensify with climate change., (© 2024. The Author(s).)

Objective: The aim of this work is to examine suicide intent disclosures to identify patterns to support an improved understanding of the impetus for suicidal behavior in late life, which may offer insight useful in aiding prevention efforts., Methods: Using restricted access data from the National Violent Death Reporting System for years 2016-2018, we conducted qualitative content analysis of included narrative descriptions of 2,969 cases in which the decedent was aged 65 years or older and disclosed their intent to die by suicide., Results: The majority of suicide intent disclosures were direct statements of intent to die by suicide (37.19%), followed by a smaller proportion of indirect (implied) statements (25.29%). When response of disclosure recipient was described, such disclosures were frequently dismissed as insincere. Uncontrolled or chronic pain was cited by 11.62% of decedents as the rationale for suicide., Conclusion: Findings from this work suggest the content of suicide intent disclosures may vary considerably but demonstrate consistent patterns. Dismissal of such disclosures is a common response, likely due to inability to assess sincerity. Given the high rate of lethality among suicide attempts in late life, any intent disclosures should be critically evaluated.

Rice grain is widely consumed as a staple food, providing essential nutrition for households, particularly marginalized families. It plays a crucial role in ensuring food security, promoting human nutrition, supporting good health, and contributing to global food and nutritional security. Addressing the diverse quality demands of emerging diverse and climate-risked population dietary needs requires the development of a single variety of rice grain that can meet the various dietary and nutritional requirements. However, there is a lack of concrete definition for rice grain quality, making it challenging to cater to the different demands. The lack of sufficient genetic study and development in improving rice grain quality has resulted in widespread malnutrition, hidden hunger, and micronutrient deficiencies affecting a significant portion of the global population. Therefore, it is crucial to identify genetically evolved varieties with marked qualities that can help address these issues. Various factors account for the declining quality of rice grain and requires further study to improve their quality for healthier diets. We characterized rice grain quality using Lancastrians descriptor and a multitude of intrinsic and extrinsic quality traits. Next, we examined various components of rice grain quality favored in the Asia-Pacific region. This includes preferences by different communities, rice industry stakeholders, and value chain actors. We also explored the biological aspects of rice grain quality in the region, as well as specific genetic improvements that have been made in these traits. Additionally, we evaluated the factors that can influence rice grain quality and discussed the future directions for ensuring food and nutritional security and meeting consumer demands for grain quality. We explored the diverse consumer bases and their varied preferences in Asian-Pacific countries including India, China, Nepal, Bhutan, Vietnam, Sri Lanka, Pakistan, Thailand, Cambodia, Philippines, Bangladesh, Indonesia, Korea, Myanmar and Japan. The quality preferences encompassed a range of factors, including rice head recovery, grain shape, uniform size before cooking, gelatinization, chalkiness, texture, amylose content, aroma, red-coloration of grain, soft and shine when cooked, unbroken when cooked, gelatinization, less water required for cooking, gelatinization temperature (less cooking time), aged rice, firm and dry when cooked (gel consistency), extreme white, soft when chewed, easy-to-cook rice (parboiled rice), vitamins, and minerals. These preferences were evaluated across high, low, and medium categories. A comprehensive analysis is provided on the enhancement of grain quality traits, including brown rice recovery, recovery rate of milled rice, head rice recovery, as well as morphological traits such as grain length, grain width, grain length-width ratio, and grain chalkiness. We also explored the characteristics of amylose, gel consistency, gelatinization temperature, viscosity, as well as the nutritional qualities of rice grains such as starch, protein, lipids, vitamins, minerals, phytochemicals, and bio-fortification potential. The various factors that impact the quality of rice grains, including pre-harvest, post-harvest, and genotype considerations were explored. Additionally, we discussed the future direction and genetic strategies to effectively tackle these challenges. These qualitative characteristics represent the fundamental focus of regional and national breeding strategies employed by different countries to meet consumer preference. Given the significance of rice as a staple food in Asia-Pacific countries, it is primarily consumed domestically, with only a small portion being exported internationally. All the important attributes must be clearly defined within specific parameters. It is crucial for geneticists and breeders to develop a rice variety that can meet the diverse demands of consumers worldwide by incorporating multiple desirable traits. Thus, the goal of addressing global food and nutritional security, and human healthy can be achieved., (© 2024. The Author(s).)

Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) expresses the Panton-Valentine leukocidin (PVL) virulence gene, which is associated with community and hospital-acquired severe MRSA infections. The objective of this study was to determine the prevalence and antibiotic susceptibility profile with a focus on the presence of the PVL gene among MRSA isolates in healthcare settings., Methodology: A total of 1,207 clinical specimens and 304 hospital environment swabs were collected in a tertiary care hospital in Nepal, and investigated following basic microbiological techniques. S. aureus was confirmed with the coagulase test. An antibiotic susceptibility test (AST) was performed by the Kirby-Bauer method and screening for MRSA was carried out by the cefoxitin disc diffusion method guided by the Clinical and Laboratory Standards Institute (CLSI), 2020. DNA was extracted and used in a polymerase chain reaction (PCR) to detect mecA and PVL genes., Results: Of the 1,511 samples, 45 (2.9%) S. aureus (23 clinical and 22 environmental) were isolated. Among them, 69.6% (16/23) and 27.3% (6/22) were MRSA in clinical and environmental isolates, respectively. Twelve (52.2%) clinical isolates and seven (31.8%) environmental isolates were multidrug resistant. The majority of isolates were susceptible to vancomycin and linezolid. The PVL gene was detected in 18.2% (n = 4/22) of the MRSA isolates, of which three were from clinical sources and one was from an environmental swab., Conclusions: The prevalence of MRSA, and PVL-producing S. aureus were higher in the hospital setting. Hence, immediate and urgent implementation of infection control and sanitation measures are needed in the hospital., Competing Interests: No Conflict of Interest is declared, (Copyright (c) 2024 Gopiram Syangtan, Laxmi K Khanal, Shrijana Bista, Arun B Chand, Bijaya L Maharajhan, Prabin Dawadi, Reshma Tuladhar, Shiba K Rai, Dev R Joshi.)

High-precision virtual environments are increasingly important for various education, simulation, training, performance, and entertainment applications. We present HoloCamera, an innovative volumetric capture instrument to rapidly acquire, process, and create cinematic-quality virtual avatars and scenarios. The HoloCamera consists of a custom-designed free-standing structure with 300 high-resolution RGB cameras mounted with uniform spacing spanning the four sides and the ceiling of a room-sized studio. The light field acquired from these cameras is streamed through a distributed array of GPUs that interleave the processing and transmission of 4K resolution images. The distributed compute infrastructure that powers these RGB cameras consists of 50 Jetson AGX Xavier boards, with each processing unit dedicated to driving and processing imagery from six cameras. A high-speed Gigabit Ethernet network fabric seamlessly interconnects all computing boards. In this systems paper, we provide an in-depth description of the steps involved and lessons learned in constructing such a cutting-edge volumetric capture facility that can be generalized to other such facilities. We delve into the techniques employed to achieve precise frame synchronization and spatial calibration of cameras, careful determination of angled camera mounts, image processing from the camera sensors, and the need for a resilient and robust network infrastructure. To advance the field of volumetric capture, we are releasing a high-fidelity static light-field dataset, which will serve as a benchmark for further research and applications of cinematic-quality volumetric light fields.