Author: "Biskup E" - Searchworks@Jio Institute Digital Library Search Results

Your search keyword '"Biskup E"' showing total 260 results

Start Over Author "Biskup E"

260 results on '"Biskup E"'

1. Efficacy of Active Rapid Molecular Screening and IPC Interventions on Carbapenem-Resistant Enterobacterales Infections in Emergency Intensive Care Units without Enough Single-Room Isolation

Author: Yang S, He L, Li K, Yu X, Ni L, Hu L, Guo J, Biskup E, Tang L, and Wu W
Subjects: carbapenem-resistant, enterobacterales, active screening, infection prevention and control intervention, emergency intensive care unit, nosocomial infection, Infectious and parasitic diseases, RC109-216
Abstract: Simin Yang,1,&ast; Lihua He,2,&ast; Ke Li,3,&ast; Xiaoyu Yu,1 Lijun Ni,1 Liang Hu,1 Jian Guo,1 Ewelina Biskup,4,5 Lunxian Tang,3 Wenjuan Wu1 1Department of Laboratory Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 2Department of Hospital Infection Management, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 3Department of Emergency Intensive Care Unit, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, People’s Republic of China; 4Department of Basic and Clinical Medicine, Shanghai University of Medicine and Health Sciences, Shanghai, People’s Republic of China; 5Department of Internal Medicine, University Hospital of Basel, Basel, Switzerland&ast;These authors contributed equally to this workCorrespondence: Lunxian Tang; Wenjuan Wu, Tel +86-15921155750 ; +86-13386057159, Email 456tlx@163.com; wwj1210@126.comPurpose: To investigate whether rapid active molecular screening and infection prevention and control (IPC) interventions can reduce colonization or infection with carbapenem-resistant Enterobacterales (CRE) in a general emergency intensive care unit (EICU) without enough single-room isolation.Methods: The study was designed as a before-and-after quasi-experiment. Before the experimental period, the ward was rescheduled and the staff were trained. From May 2018 to April 2021, active screening was performed by seminested real-time fluorescent polymerase chain reaction (PCR) detection with rectal swabs from all patients on admission to the EICU, and the results were reported in 1 hour. Other IPC interventions including hand hygiene, contact precautions, patient isolation, environmental disinfection, environment surveillance, monitoring, auditing and feedback were conducted under strict supervision. The patients’ clinical characteristics were collected simultaneously.Results: In this 3-year study, 630 patients were enrolled and 19.84% of the patients were initially colonized or infected with CRE as shown by active molecular screening. The average drug resistance ratio to carbapenem shown by clinical culture detection of Klebsiella pneumoniae (KPN) before the study was performed was 71.43% in EICU. The drug resistance ratio decreased significantly from 75%, 66.67% to 46.67% in the next 3 years (p< 0.05) during which active screening and IPC interventions were strictly executed. While the ratio gaps between EICU and the whole hospital were narrowed from 22.81%, 21.11% to 4.64%. Patients with invasive devices, skin barrier damage, and the recent use of antibiotics on admission were found to have a higher risk of being colonized or infected with CRE (p< 0.05).Conclusion: Active rapid molecular screening and other IPC interventions may significantly reduce CRE nosocomial infections even in wards without enough single-room isolation. The key to reduce the spread of CRE in the EICU is the strict execution of IPC interventions by all medical staff and healthcare workers.Keywords: carbapenem-resistant, Enterobacterales, active screening, infection prevention and control intervention, emergency intensive care unit, nosocomial infection
Published: 2023

2. V

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

3. T

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

4. U

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

5. R

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

6. Q

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

7. S

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

8. P

Author: Hänsel, Rudolf, Rimpler, Horst, Keller, Konstantin, Schneider, Georg, Abel, G., Bader, G., Baumann, T., Bertram, B., Beyer, G., Bodesheim, U., Brand, N., Brautigam, M., Brenneisen, R., Burger, A., Burghart, J., Chaurasia, N., Eilert, U., Ennet, D., Ferstl, W., Frank, B., Gehrmann, B., Goez, C., Gomaa, K., Gorecki, P., Hansel, R., Harnischfeger, G., Hasler, F., Hecker, E., Heni, J., Henkler, G., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Holzl, J., Horz, K-H, Hubner, W-D, lsaac, O., Juretzek, W., Kampfer, M., Kletter, C., Koch, H., Koehler, H., Konig, G., Kraus, J., Kreher, B., Krenn, L., Kretschmer, H., Kudicke, S., Laux, P., Meier, B., Meier-Liebi, M., Merfort, I., Moeck, S., Mundt, S., Reher, G., Rehwald, A., Reichling, J., Roder, E., Rothe, C., Rzadkowska-Bodalska, H., Schilz, W., Schleinitz, H., Schneider, G., Schneider, K., Schollhorn, T., Scholz, E., Schopke, T., Schulz, V., Schwarz-Schulz, B., Schwarze, H., Schweins, S., Seitz, R., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stalder, A-B, Stuppner, H., Teuscher, E., Tewocht, G., Thomas, A., Veit, M., Wink, M., Wolf, H., Hänsel, Rudolf, editor, Rimpler, Horst, editor, Keller, Konstantin, editor, Schneider, Georg, editor, Abel, G., editor, Bader, G., editor, Baumann, T., editor, Bertram, B., editor, Beyer, G., editor, Bodesheim, U., editor, Brand, N., editor, Brautigam, M., editor, Brenneisen, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Frank, B., editor, Gehrmann, B., editor, Goez, C., editor, Gomaa, K., editor, Gorecki, P., editor, Hansel, R., editor, Harnischfeger, G., editor, Hasler, F., editor, Hecker, E., editor, Heni, J., editor, Henkler, G., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Holzl, J., editor, Horz, K-H, editor, Hubner, W-D, editor, lsaac, O., editor, Juretzek, W., editor, Kampfer, M., editor, Kletter, C., editor, Koch, H., editor, Koehler, H., editor, Konig, G., editor, Kraus, J., editor, Kreher, B., editor, Krenn, L., editor, Kretschmer, H., editor, Kudicke, S., editor, Laux, P., editor, Meier, B., editor, Meier-Liebi, M., editor, Merfort, I., editor, Moeck, S., editor, Mundt, S., editor, Reher, G., editor, Rehwald, A., editor, Reichling, J., editor, Roder, E., editor, Rothe, C., editor, Rzadkowska-Bodalska, H., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, G., editor, Schneider, K., editor, Schollhorn, T., editor, Scholz, E., editor, Schopke, T., editor, Schulz, V., editor, Schwarz-Schulz, B., editor, Schwarze, H., editor, Schweins, S., editor, Seitz, R., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stalder, A-B, editor, Stuppner, H., editor, Teuscher, E., editor, Tewocht, G., editor, Thomas, A., editor, Veit, M., editor, Wink, M., editor, and Wolf, H., editor
Published: 1994
Full Text: View/download PDF

9. M

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

10. K

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

11. L

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

12. J

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

13. F

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

14. G

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

15. E

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

16. H

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

17. I

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

18. O

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

19. N

Author: von Bruchhausen, F., Dannhardt, G., Ebel, S., Frahm, A. W., Hackenthal, E., Hänsel, R., Holzgrabe, U., Keller, K., Nürnberg, E., Rimpler, H., Schneider, G., Surmann, P., Wolf, H. U., Wurm, G., Aye, R. D., Bader, G., Bauer, I., Bauer, R., Becker, H., Beyer, G., Blaschek, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Broese, R., Burger, A., Burghart, J., Chaurasia, N., Cholcha, W., Eilert, U., Ennet, D., Ferstl, W., Fiegert, E., Gaedcke, F., Gehrmann, B., Gomaa, K., Gorecki, P., Grubert, M. W., Harnischfeger, G., Helmlin, H. J., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Holz, W., Hölzl, J., Horz, K. H., Isaac, O., Jerga, C., Juretzek, W., Kartnig, T., Koch, H. P., Koehler, H., Kraus, L., Kreis, W., Leng-Peschlow, E., Liersch, R., Lindequist, U., Mechler, E., Meier, B., Meier-Liebi, M., Menßen, H. G., Merfort, I., Miething, H., Moeck, S., Mundt, S., Münzing-Vasirian, K., Noster, S., Ohem, N., Paper, D., Reichling, J., Schilz, W., Schleinitz, H., Schneider, E., Scholz, E., Schöpke, T., Schulz, V., Schütt, H., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Sonnenborn, U., Spieß, E., Ssymank, V., Staesche, K., Stahl-Biskup, E., Stuppner, H., Teuscher, E., Veit, M., Wiebrecht, A., Wink, M., Wissinger-Gräfenhahn, U., Wohlfart, R., Zepernick, B., von Bruchhausen, F., editor, Dannhardt, G., editor, Ebel, S., editor, Frahm, A. W., editor, Hackenthal, E., editor, Hänsel, R., editor, Holzgrabe, U., editor, Keller, K., editor, Nürnberg, E., editor, Rimpler, H., editor, Schneider, G., editor, Surmann, P., editor, Wolf, H. U., editor, Wurm, G., editor, Aye, R. D., editor, Bader, G., editor, Bauer, I., editor, Bauer, R., editor, Becker, H., editor, Beyer, G., editor, Blaschek, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Broese, R., editor, Burger, A., editor, Burghart, J., editor, Chaurasia, N., editor, Cholcha, W., editor, Eilert, U., editor, Ennet, D., editor, Ferstl, W., editor, Fiegert, E., editor, Gaedcke, F., editor, Gehrmann, B., editor, Gomaa, K., editor, Gorecki, P., editor, Grubert, M. W., editor, Harnischfeger, G., editor, Helmlin, H. J., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Holz, W., editor, Hölzl, J., editor, Horz, K. H., editor, Isaac, O., editor, Jerga, C., editor, Juretzek, W., editor, Kartnig, T., editor, Koch, H. P., editor, Koehler, H., editor, Kraus, L., editor, Kreis, W., editor, Leng-Peschlow, E., editor, Liersch, R., editor, Lindequist, U., editor, Mechler, E., editor, Meier, B., editor, Meier-Liebi, M., editor, Menßen, H. G., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Münzing-Vasirian, K., editor, Noster, S., editor, Ohem, N., editor, Paper, D., editor, Reichling, J., editor, Schilz, W., editor, Schleinitz, H., editor, Schneider, E., editor, Scholz, E., editor, Schöpke, T., editor, Schulz, V., editor, Schütt, H., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Sonnenborn, U., editor, Spieß, E., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Stuppner, H., editor, Teuscher, E., editor, Veit, M., editor, Wiebrecht, A., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, Wohlfart, R., editor, and Zepernick, B., editor
Published: 1993
Full Text: View/download PDF

20. D

Author: Hänsel, R., Keller, K., Rimpler, H., Schneider, G., Aye, R. D., Bauer, I., Baumann, T. W., Beck, M., Beil, A., Blascheck, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Burger, A., Carle, R., Chaurasia, N., Diettrich, B., Eilert, U., Ferstl, W., Fett, M., Franck, G., Frank, B., Gehrmann, B., Gorecki, P., Gracza, L., Greiner, S., Grubert, M. W., Hampe, S., Harnischfeger, G., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Hölscher, U., Horz, K.-H., Isaac, O., Junior, P., Jüptner, J., Jurenitsch, J., Kämpfer, M., Kartnig, T., Khaliefi, F., Kletter, C., Kober, M., Koch, H. P., Koehler, H., Kopp, B., Kraus, J., Kraus, Lj., Kreis, W., Langhammer, L., Liersch, R., Lindequist, U., Loew, D., Luckner, M., Mathys, K., Merfort, I., Miething, H., Moeck, S., Mundt, S., Paper, D., Pilgrim, H., Proksch, P., Ratka, O., Rauwald, H.-W., Reichling, J., Schennen, C., Schilz, W., Schleinitz, H., Schmidt, S., Schneider, K., Scholz, E., Schöpke, T., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Siegers, C.-P., Simon, P., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Steuding, W., Stuppner, H., Teuscher, E., Thober-Miething, H., Uehleke, B., Veit, M., Warncke, D., Wink, M., Wissinger-Gräfenhahn, U., Zepernick, B., Hänsel, R., editor, Keller, K., editor, Rimpler, H., editor, Schneider, G., editor, Aye, R. D., editor, Bauer, I., editor, Baumann, T. W., editor, Beck, M., editor, Beil, A., editor, Blascheck, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Burger, A., editor, Carle, R., editor, Chaurasia, N., editor, Diettrich, B., editor, Eilert, U., editor, Ferstl, W., editor, Fett, M., editor, Franck, G., editor, Frank, B., editor, Gehrmann, B., editor, Gorecki, P., editor, Gracza, L., editor, Greiner, S., editor, Grubert, M. W., editor, Hampe, S., editor, Harnischfeger, G., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Hölscher, U., editor, Horz, K.-H., editor, Isaac, O., editor, Junior, P., editor, Jüptner, J., editor, Jurenitsch, J., editor, Kämpfer, M., editor, Kartnig, T., editor, Khaliefi, F., editor, Kletter, C., editor, Kober, M., editor, Koch, H. P., editor, Koehler, H., editor, Kopp, B., editor, Kraus, J., editor, Kraus, Lj., editor, Kreis, W., editor, Langhammer, L., editor, Liersch, R., editor, Lindequist, U., editor, Loew, D., editor, Luckner, M., editor, Mathys, K., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Paper, D., editor, Pilgrim, H., editor, Proksch, P., editor, Ratka, O., editor, Rauwald, H.-W., editor, Reichling, J., editor, Schennen, C., editor, Schilz, W., editor, Schleinitz, H., editor, Schmidt, S., editor, Schneider, K., editor, Scholz, E., editor, Schöpke, T., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Siegers, C.-P., editor, Simon, P., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Steuding, W., editor, Stuppner, H., editor, Teuscher, E., editor, Thober-Miething, H., editor, Uehleke, B., editor, Veit, M., editor, Warncke, D., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, and Zepernick, B., editor
Published: 1992
Full Text: View/download PDF

21. C

Author: Hänsel, R., Keller, K., Rimpler, H., Schneider, G., Aye, R. D., Bauer, I., Baumann, T. W., Beck, M., Beil, A., Blascheck, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Burger, A., Carle, R., Chaurasia, N., Diettrich, B., Eilert, U., Ferstl, W., Fett, M., Franck, G., Frank, B., Gehrmann, B., Gorecki, P., Gracza, L., Greiner, S., Grubert, M. W., Hampe, S., Harnischfeger, G., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Hölscher, U., Horz, K.-H., Isaac, O., Junior, P., Jüptner, J., Jurenitsch, J., Kämpfer, M., Kartnig, T., Khaliefi, F., Kletter, C., Kober, M., Koch, H. P., Koehler, H., Kopp, B., Kraus, J., Kraus, Lj., Kreis, W., Langhammer, L., Liersch, R., Lindequist, U., Loew, D., Luckner, M., Mathys, K., Merfort, I., Miething, H., Moeck, S., Mundt, S., Paper, D., Pilgrim, H., Proksch, P., Ratka, O., Rauwald, H.-W., Reichling, J., Schennen, C., Schilz, W., Schleinitz, H., Schmidt, S., Schneider, K., Scholz, E., Schöpke, T., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Siegers, C.-P., Simon, P., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Steuding, W., Stuppner, H., Teuscher, E., Thober-Miething, H., Uehleke, B., Veit, M., Warncke, D., Wink, M., Wissinger-Gräfenhahn, U., Zepernick, B., Hänsel, R., editor, Keller, K., editor, Rimpler, H., editor, Schneider, G., editor, Aye, R. D., editor, Bauer, I., editor, Baumann, T. W., editor, Beck, M., editor, Beil, A., editor, Blascheck, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Burger, A., editor, Carle, R., editor, Chaurasia, N., editor, Diettrich, B., editor, Eilert, U., editor, Ferstl, W., editor, Fett, M., editor, Franck, G., editor, Frank, B., editor, Gehrmann, B., editor, Gorecki, P., editor, Gracza, L., editor, Greiner, S., editor, Grubert, M. W., editor, Hampe, S., editor, Harnischfeger, G., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Hölscher, U., editor, Horz, K.-H., editor, Isaac, O., editor, Junior, P., editor, Jüptner, J., editor, Jurenitsch, J., editor, Kämpfer, M., editor, Kartnig, T., editor, Khaliefi, F., editor, Kletter, C., editor, Kober, M., editor, Koch, H. P., editor, Koehler, H., editor, Kopp, B., editor, Kraus, J., editor, Kraus, Lj., editor, Kreis, W., editor, Langhammer, L., editor, Liersch, R., editor, Lindequist, U., editor, Loew, D., editor, Luckner, M., editor, Mathys, K., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Paper, D., editor, Pilgrim, H., editor, Proksch, P., editor, Ratka, O., editor, Rauwald, H.-W., editor, Reichling, J., editor, Schennen, C., editor, Schilz, W., editor, Schleinitz, H., editor, Schmidt, S., editor, Schneider, K., editor, Scholz, E., editor, Schöpke, T., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Siegers, C.-P., editor, Simon, P., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Steuding, W., editor, Stuppner, H., editor, Teuscher, E., editor, Thober-Miething, H., editor, Uehleke, B., editor, Veit, M., editor, Warncke, D., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, and Zepernick, B., editor
Published: 1992
Full Text: View/download PDF

22. B

Author: Hänsel, R., Keller, K., Rimpler, H., Schneider, G., Aye, R. D., Bauer, I., Baumann, T. W., Beck, M., Beil, A., Blascheck, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Burger, A., Carle, R., Chaurasia, N., Diettrich, B., Eilert, U., Ferstl, W., Fett, M., Franck, G., Frank, B., Gehrmann, B., Gorecki, P., Gracza, L., Greiner, S., Grubert, M. W., Hampe, S., Harnischfeger, G., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Hölscher, U., Horz, K.-H., Isaac, O., Junior, P., Jüptner, J., Jurenitsch, J., Kämpfer, M., Kartnig, T., Khaliefi, F., Kletter, C., Kober, M., Koch, H. P., Koehler, H., Kopp, B., Kraus, J., Kraus, Lj., Kreis, W., Langhammer, L., Liersch, R., Lindequist, U., Loew, D., Luckner, M., Mathys, K., Merfort, I., Miething, H., Moeck, S., Mundt, S., Paper, D., Pilgrim, H., Proksch, P., Ratka, O., Rauwald, H.-W., Reichling, J., Schennen, C., Schilz, W., Schleinitz, H., Schmidt, S., Schneider, K., Scholz, E., Schöpke, T., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Siegers, C.-P., Simon, P., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Steuding, W., Stuppner, H., Teuscher, E., Thober-Miething, H., Uehleke, B., Veit, M., Warncke, D., Wink, M., Wissinger-Gräfenhahn, U., Zepernick, B., Hänsel, R., editor, Keller, K., editor, Rimpler, H., editor, Schneider, G., editor, Aye, R. D., editor, Bauer, I., editor, Baumann, T. W., editor, Beck, M., editor, Beil, A., editor, Blascheck, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Burger, A., editor, Carle, R., editor, Chaurasia, N., editor, Diettrich, B., editor, Eilert, U., editor, Ferstl, W., editor, Fett, M., editor, Franck, G., editor, Frank, B., editor, Gehrmann, B., editor, Gorecki, P., editor, Gracza, L., editor, Greiner, S., editor, Grubert, M. W., editor, Hampe, S., editor, Harnischfeger, G., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Hölscher, U., editor, Horz, K.-H., editor, Isaac, O., editor, Junior, P., editor, Jüptner, J., editor, Jurenitsch, J., editor, Kämpfer, M., editor, Kartnig, T., editor, Khaliefi, F., editor, Kletter, C., editor, Kober, M., editor, Koch, H. P., editor, Koehler, H., editor, Kopp, B., editor, Kraus, J., editor, Kraus, Lj., editor, Kreis, W., editor, Langhammer, L., editor, Liersch, R., editor, Lindequist, U., editor, Loew, D., editor, Luckner, M., editor, Mathys, K., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Paper, D., editor, Pilgrim, H., editor, Proksch, P., editor, Ratka, O., editor, Rauwald, H.-W., editor, Reichling, J., editor, Schennen, C., editor, Schilz, W., editor, Schleinitz, H., editor, Schmidt, S., editor, Schneider, K., editor, Scholz, E., editor, Schöpke, T., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Siegers, C.-P., editor, Simon, P., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Steuding, W., editor, Stuppner, H., editor, Teuscher, E., editor, Thober-Miething, H., editor, Uehleke, B., editor, Veit, M., editor, Warncke, D., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, and Zepernick, B., editor
Published: 1992
Full Text: View/download PDF

23. A

Author: Hänsel, R., Keller, K., Rimpler, H., Schneider, G., Aye, R. D., Bauer, I., Baumann, T. W., Beck, M., Beil, A., Blascheck, W., Brand, N., Braun-Sprakties, U., Brenneisen, R., Burger, A., Carle, R., Chaurasia, N., Diettrich, B., Eilert, U., Ferstl, W., Fett, M., Franck, G., Frank, B., Gehrmann, B., Gorecki, P., Gracza, L., Greiner, S., Grubert, M. W., Hampe, S., Harnischfeger, G., Henkler, G., Hensel, A., Heubl, G., Hiermann, A., Hiller, K., Hoffmann-Bohm, K., Hohmann, B., Hölscher, U., Horz, K.-H., Isaac, O., Junior, P., Jüptner, J., Jurenitsch, J., Kämpfer, M., Kartnig, T., Khaliefi, F., Kletter, C., Kober, M., Koch, H. P., Koehler, H., Kopp, B., Kraus, J., Kraus, Lj., Kreis, W., Langhammer, L., Liersch, R., Lindequist, U., Loew, D., Luckner, M., Mathys, K., Merfort, I., Miething, H., Moeck, S., Mundt, S., Paper, D., Pilgrim, H., Proksch, P., Ratka, O., Rauwald, H.-W., Reichling, J., Schennen, C., Schilz, W., Schleinitz, H., Schmidt, S., Schneider, K., Scholz, E., Schöpke, T., Schwarze, H., Schweins, S., Schwell, B., Seitz, R., Siegers, C.-P., Simon, P., Sonnenborn, U., Ssymank, V., Staesche, K., Stahl-Biskup, E., Steuding, W., Stuppner, H., Teuscher, E., Thober-Miething, H., Uehleke, B., Veit, M., Warncke, D., Wink, M., Wissinger-Gräfenhahn, U., Zepernick, B., Hänsel, R., editor, Keller, K., editor, Rimpler, H., editor, Schneider, G., editor, Aye, R. D., editor, Bauer, I., editor, Baumann, T. W., editor, Beck, M., editor, Beil, A., editor, Blascheck, W., editor, Brand, N., editor, Braun-Sprakties, U., editor, Brenneisen, R., editor, Burger, A., editor, Carle, R., editor, Chaurasia, N., editor, Diettrich, B., editor, Eilert, U., editor, Ferstl, W., editor, Fett, M., editor, Franck, G., editor, Frank, B., editor, Gehrmann, B., editor, Gorecki, P., editor, Gracza, L., editor, Greiner, S., editor, Grubert, M. W., editor, Hampe, S., editor, Harnischfeger, G., editor, Henkler, G., editor, Hensel, A., editor, Heubl, G., editor, Hiermann, A., editor, Hiller, K., editor, Hoffmann-Bohm, K., editor, Hohmann, B., editor, Hölscher, U., editor, Horz, K.-H., editor, Isaac, O., editor, Junior, P., editor, Jüptner, J., editor, Jurenitsch, J., editor, Kämpfer, M., editor, Kartnig, T., editor, Khaliefi, F., editor, Kletter, C., editor, Kober, M., editor, Koch, H. P., editor, Koehler, H., editor, Kopp, B., editor, Kraus, J., editor, Kraus, Lj., editor, Kreis, W., editor, Langhammer, L., editor, Liersch, R., editor, Lindequist, U., editor, Loew, D., editor, Luckner, M., editor, Mathys, K., editor, Merfort, I., editor, Miething, H., editor, Moeck, S., editor, Mundt, S., editor, Paper, D., editor, Pilgrim, H., editor, Proksch, P., editor, Ratka, O., editor, Rauwald, H.-W., editor, Reichling, J., editor, Schennen, C., editor, Schilz, W., editor, Schleinitz, H., editor, Schmidt, S., editor, Schneider, K., editor, Scholz, E., editor, Schöpke, T., editor, Schwarze, H., editor, Schweins, S., editor, Schwell, B., editor, Seitz, R., editor, Siegers, C.-P., editor, Simon, P., editor, Sonnenborn, U., editor, Ssymank, V., editor, Staesche, K., editor, Stahl-Biskup, E., editor, Steuding, W., editor, Stuppner, H., editor, Teuscher, E., editor, Thober-Miething, H., editor, Uehleke, B., editor, Veit, M., editor, Warncke, D., editor, Wink, M., editor, Wissinger-Gräfenhahn, U., editor, and Zepernick, B., editor
Published: 1992
Full Text: View/download PDF

24. Sepsis at ICU admission does not decrease 30-day survival in very old patients : a post-hoc analysis of the VIP1 multinational cohort study

Author: Ibarz, Mercedes, Boumendil, Ariane, Haas, Lenneke E M, Irazabal, Marian, Flaatten, Hans, de Lange, Dylan W, Morandi, Alessandro, Andersen, Finn H, Bertolini, Guido, Cecconi, Maurizio, Christensen, Steffen, Faraldi, Loredana, Fjølner, Jesper, Jung, Christian, Marsh, Brian, Moreno, Rui, Oeyen, Sandra, Öhman, Christina Agwald, Bollen Pinto, Bernardo, Soliman, Ivo W, Szczeklik, Wojciech, Valentin, Andreas, Watson, Ximena, Zaferidis, Tilemachos, Guidet, Bertrand, Artigas, Antonio, Schmutz R, Wimmer F, Eller P, Joannidis M, De Buysscher P, De Neve N, Oeyen S, Swinnen W, Bollen Pinto B, Abraham P, Hergafi L, Schefold JC, Biskup E, Piza P, Taliadoros I, Fjølner J, Dey N, Sølling C, Rasmussen BS, Christensen S, Forceville X, Besch G, Mentec H, Michel P, Mateu P, Vettoretti L, Bourenne J, Marin N, Guillot M, Aissaoui N, Goulenok C, Thieulot-Rolin N, Messika J, Lamhaut L, Guidet B, Charron C, Lauten A, Sacher AL, Brenner T, Franz M, Bloos F, Ebelt H, Schaller SJ, Fuest K, Rabe C, Dieck T, Steiner S, Graf T, Nia AM, Jung C, Janosi RA, Meybohm P, Simon P, Utzolino S, Rahmel T, Barth E, Schuster M, Aidoni Z, Aloizos S, Tasioudis P, Lampiri K, Zisopoulou V, Ravani I, Pagaki E, Antoniou A, Katsoulas TA, Kounougeri A, Marinakis G, Tsimpoukas F, Spyropoulou A, Zygoulis P, Kyparissi A, Gupta M, Gurjar M, Maji IM, Hayes I, Marsh B, Kelly Y, Westbrook A, Fitzpatrick G, Maheshwari D, Motherway C, Negri G, Spadaro S, Nattino G, Pedeferri M, Boscolo A, Rossi S, Calicchio G, Cubattoli L, Di Lascio G, Barbagallo M, Berruto F, Codazzi D, Bottazzi A, Fumagalli P, Negro G, Lupi G, Savelli F, Vulcano GA, Fumagalli R, Marudi A, Lefons U, Lembo R, Babini M, Paggioro A, Parrini V, Zaccaria M, Clementi S, Gigliuto C, Facondini F, Pastorini S, Munaron S, Calamai I, Bocchi A, Adorni A, Bocci MG, Cortegiani A, Casalicchio T, Melia S, Graziani E, Barattini M, Brizio E, Rossi M, Hahn M, Flattens H, Kemmerer N, Streiter HF, Dybwik K, Legernaes T, Klepstad P, Olaussen EB, Olsen KI, Brresen OM, Bjorsvik G, Andersen FH, Maini S, Fehrle L, Czuczwar M, Krawczyk P, Ziętkiewicz M, Nowak ŁR, Kotfis K, Cwyl K, Gajdosz R, Biernawska J, Bohatyrewicz R, Gawda R, Grudzień P, Nasiłowski P, Popek N, Cyrankiewicz W, Wawrzyniak K, Wnuk M, Maciejewski D, Studzińska D, Żukowski M, Bernas S, Piechota M, Szczeklik W, Nowak-Kózka I, Fronczek J, Serwa M, Machała W, Stefaniak J, Wujtewicz M, Szymkowiak M, Adamik B, Polok K, Włudarczyk A, Górka J, Kozera N, Goździk W, Catorze N, Branco MC, Barros I, Barros N, Krystopchuk A, Honrado T, Sousa C, Munoz F, Rebelo M, Gomes R, Nunes J, Dias C, Fernandes AM, Petrisor C, Constantin B, Belskiy V, Boskholov B, Rodriguez E, Rebollo S, Aguilar G, Masdeu G, Jaimes MI, Mira ÁP, Bodi MA, Barea Mendoza JA, López-Cuenca S, Guzman MH, Rico-Feijoo J, Ibarz M, Alvarez JT, Kawati R, Sivik J, Nauska J, Smole D, Parenmark F, Lyrén J, Rockstrohm K, Rydén S, Spångfors M, Strinnholm M, Walther S, De Geer L, Nordlund P, Pålsson S, Zetterquist H, Nilsson A, Thiringer K, Jungner M, Bark B, Nordling B, Sköld H, Brorsson C, Persson S, Bergström A, Berkius J, Holmström J, van Dijk I, Haas LEM, Ramnarain D, Jansen T, Nooteboom F, van der Voort PHJ, de Lange D, Dieperink W, de Waard MC, de Smet AGE, Bormans L, Dormans T, Dempsey G, Mathew SJ, Raj AS, Grecu I, Cupitt J, Lawton T, Clark R, Popescu M, Spittle N, Faulkner M, Cowton A, Elloway E, Williams P, Reay M, Chukkambotla S, Kumar R, Al-Subaie N, Kent L, Tamm T, Kajtor I, Burns K, Pugh R, Ostermann M, Kam E, Bowyer H, Smith N, Templeton M, Henning J, Goffin K, Kapoor R, Laha S, Chilton P, Khaliq W, Crayford A, Coetzee S, Tait M, Stoker W, Gimenez M, Pope A, Camsooksai J, Pogson D, Quigley K, Ritzema J, Hormis A, Boulanger C, Balasubramaniam M, Vamplew L, Burt K, Martin D, Craig J, Prowle J, Doyle N, Shelton J, Scott C, Donnison P, Shelton S, Frey C, Ryan C, Spray D, Barnes V, Barnes K, Ridgway S, Saha R, Clark T, Wood J, Bolger C, Bassford C, Lewandowski J, Zhao X, Humphreys S, Dowling S, Richardson N, Burtenshaw A, Stevenson C, Wilcock D, Nalapko Y., Ibarz, M, Boumendil, A, Haas, L, Irazabal, M, Flaatten, H, de Lange, D, Morandi, A, Andersen, F, Bertolini, G, Cecconi, M, Christensen, S, Faraldi, L, Fjolner, J, Jung, C, Marsh, B, Moreno, R, Oeyen, S, Ohman, C, Bollen Pinto, B, Soliman, I, Szczeklik, W, Valentin, A, Watson, X, Zaferidis, T, Guidet, B, Artigas, A, Schmutz, R, Wimmer, F, Eller, P, Joannidis, M, De Buysscher, P, De Neve, N, Swinnen, W, Abraham, P, Hergafi, L, Schefold, J, Biskup, E, Piza, P, Taliadoros, I, Dey, N, Solling, C, Rasmussen, B, Forceville, X, Besch, G, Mentec, H, Michel, P, Mateu, P, Vettoretti, L, Bourenne, J, Marin, N, Guillot, M, Aissaoui, N, Goulenok, C, Thieulot-Rolin, N, Messika, J, Lamhaut, L, Charron, C, Lauten, A, Sacher, A, Brenner, T, Franz, M, Bloos, F, Ebelt, H, Schaller, S, Fuest, K, Rabe, C, Dieck, T, Steiner, S, Graf, T, Nia, A, Janosi, R, Meybohm, P, Simon, P, Utzolino, S, Rahmel, T, Barth, E, Schuster, M, Aidoni, Z, Aloizos, S, Tasioudis, P, Lampiri, K, Zisopoulou, V, Ravani, I, Pagaki, E, Antoniou, A, Katsoulas, T, Kounougeri, A, Marinakis, G, Tsimpoukas, F, Spyropoulou, A, Zygoulis, P, Kyparissi, A, Gupta, M, Gurjar, M, Maji, I, Hayes, I, Kelly, Y, Westbrook, A, Fitzpatrick, G, Maheshwari, D, Motherway, C, Negri, G, Spadaro, S, Nattino, G, Pedeferri, M, Boscolo, A, Rossi, S, Calicchio, G, Cubattoli, L, Di Lascio, G, Barbagallo, M, Berruto, F, Codazzi, D, Bottazzi, A, Fumagalli, P, Negro, G, Lupi, G, Savelli, F, Vulcano, G, Fumagalli, R, Marudi, A, Lefons, U, Lembo, R, Babini, M, Paggioro, A, Parrini, V, Zaccaria, M, Clementi, S, Gigliuto, C, Facondini, F, Pastorini, S, Munaron, S, Calamai, I, Bocchi, A, Adorni, A, Bocci, M, Cortegiani, A, Casalicchio, T, Melia, S, Graziani, E, Barattini, M, Brizio, E, Rossi, M, Hahn, M, Flattens, H, Kemmerer, N, Streiter, H, Dybwik, K, Legernaes, T, Klepstad, P, Olaussen, E, Olsen, K, Brresen, O, Bjorsvik, G, Maini, S, Fehrle, L, Krawczyk, P, Zietkiewicz, M, Nowak, L, Kotfis, K, Cwyl, K, Gajdosz, R, Biernawska, J, Bohatyrewicz, R, Gawda, R, Grudzien, P, Nasilowski, P, Popek, N, Cyrankiewicz, W, Wawrzyniak, K, Wnuk, M, Maciejewski, D, Studzinska, D, Zukowski, M, Bernas, S, Piechota, M, Nowak-Kozka, I, Fronczek, J, Serwa, M, Stefaniak, J, Wujtewicz, M, Szymkowiak, M, Adamik, B, Polok, K, Wludarczyk, A, Gorka, J, Kozera, N, Gozdzik, W, Catorze, N, Branco, M, Barros, I, Barros, N, Krystopchuk, A, Honrado, T, Sousa, C, Munoz, F, Rebelo, M, Gomes, R, Nunes, J, Dias, C, Fernandes, A, Petrisor, C, Constantin, B, Belskiy, V, Boskholov, B, Rodriguez, E, Rebollo, S, Aguilar, G, Masdeu, G, Jaimes, M, Mira, A, Bodi, M, Barea Mendoza, J, Lopez-Cuenca, S, Guzman, M, Rico-Feijoo, J, Alvarez, J, Kawati, R, Sivik, J, Nauska, J, Parenmark, F, Lyren, J, Rockstrohm, K, Ryden, S, Spangfors, M, Strinnholm, M, Walther, S, De Geer, L, Nordlund, P, Palsson, S, Zetterquist, H, Nilsson, A, Thiringer, K, Jungner, M, Bark, B, Nordling, B, Skold, H, Brorsson, C, Persson, S, Bergstrom, A, Berkius, J, Holmstrom, J, van Dijk, I, Ramnarain, D, Jansen, T, Nooteboom, F, van der Voort, P, Dieperink, W, de Waard, M, de Smet, A, Bormans, L, Dormans, T, Dempsey, G, Mathew, S, Raj, A, Grecu, I, Cupitt, J, Lawton, T, Clark, R, Popescu, M, Spittle, N, Faulkner, M, Cowton, A, Elloway, E, Williams, P, Reay, M, Chukkambotla, S, Kumar, R, Al-Subaie, N, Kent, L, Tamm, T, Kajtor, I, Burns, K, Pugh, R, Ostermann, M, Kam, E, Bowyer, H, Smith, N, Templeton, M, Henning, J, Goffin, K, Kapoor, R, Laha, S, Chilton, P, Khaliq, W, Crayford, A, Coetzee, S, Tait, M, Stoker, W, Gimenez, M, Pope, A, Camsooksai, J, Pogson, D, Quigley, K, Ritzema, J, Hormis, A, Boulanger, C, Balasubramaniam, M, Vamplew, L, Burt, K, Martin, D, Craig, J, Prowle, J, Doyle, N, Shelton, J, Scott, C, Donnison, P, Shelton, S, Frey, C, Ryan, C, Spray, D, Barnes, V, Barnes, K, Ridgway, S, Saha, R, Clark, T, Wood, J, Bolger, C, Bassford, C, Lewandowski, J, Zhao, X, Humphreys, S, Dowling, S, Richardson, N, Burtenshaw, A, Stevenson, C, Wilcock, D, Nalapko, Y, Ibarz, Mercede, Boumendil, Ariane, Haas, Lenneke E M, Irazabal, Marian, Flaatten, Han, de Lange, Dylan W, Morandi, Alessandro, Andersen, Finn H, Bertolini, Guido, Cecconi, Maurizio, Christensen, Steffen, Faraldi, Loredana, Fjølner, Jesper, Jung, Christian, Marsh, Brian, Moreno, Rui, Oeyen, Sandra, Öhman, Christina Agwald, Bollen Pinto, Bernardo, Soliman, Ivo W, Szczeklik, Wojciech, Valentin, Andrea, Watson, Ximena, Zaferidis, Tilemacho, Guidet, Bertrand, Artigas, Antonio, Schmutz R, Wimmer F, Eller P, Joannidis M, De Buysscher P, De Neve N, Oeyen S, Swinnen W, Bollen Pinto B, Abraham P, Hergafi L, Schefold JC, Biskup E, Piza P, Taliadoros I, Fjølner J, Dey N, Sølling C, Rasmussen BS, Christensen S, Forceville X, Besch G, Mentec H, Michel P, Mateu P, Michel P, Vettoretti L, Bourenne J, Marin N, Guillot M, Aissaoui N, Goulenok C, Thieulot-Rolin N, Messika J, Lamhaut L, Guidet B, Charron C, Lauten A, Sacher AL, Brenner T, Franz M, Bloos F, Ebelt H, Schaller SJ, Fuest K, Rabe C, Dieck T, Steiner S, Graf T, Nia AM, Jung C, Janosi RA, Meybohm P, Simon P, Utzolino S, Rahmel T, Barth E, Jung C, Schuster M, Aidoni Z, Aloizos S, Tasioudis P, Lampiri K, Zisopoulou V, Ravani I, Pagaki E, Antoniou A, Katsoulas TA, Kounougeri A, Marinakis G, Tsimpoukas F, Spyropoulou A, Zygoulis P, Kyparissi A, Gupta M, Gurjar M, Maji IM, Hayes I, Marsh B, Kelly Y, Westbrook A, Fitzpatrick G, Maheshwari D, Motherway C, Negri G, Spadaro S, Nattino G, Pedeferri M, Boscolo A, Rossi S, Calicchio G, Cubattoli L, Di Lascio G, Barbagallo M, Berruto F, Codazzi D, Bottazzi A, Fumagalli P, Negro G, Lupi G, Savelli F, Vulcano GA, Fumagalli R, Marudi A, Lefons U, Lembo R, Babini M, Paggioro A, Parrini V, Zaccaria M, Clementi S, Gigliuto C, Facondini F, Pastorini S, Munaron S, Calamai I, Bocchi A, Adorni A, Bocci MG, Cortegiani A, Casalicchio T, Melia S, Graziani E, Barattini M, Brizio E, Rossi M, Hahn M, Flattens H, Kemmerer N, Streiter HF, Dybwik K, Legernaes T, Klepstad P, Olaussen EB, Olsen KI, Brresen OM, Bjorsvik G, Andersen FH, Maini S, Fehrle L, Czuczwar M, Krawczyk P, Ziętkiewicz M, Nowak ŁR, Kotfis K, Cwyl K, Gajdosz R, Biernawska J, Bohatyrewicz R, Gawda R, Grudzień P, Nasiłowski P, Popek N, Cyrankiewicz W, Wawrzyniak K, Wnuk M, Maciejewski D, Studzińska D, Żukowski M, Bernas S, Piechota M, Szczeklik W, Nowak-Kózka I, Fronczek J, Serwa M, Machała W, Stefaniak J, Wujtewicz M, Szymkowiak M, Adamik B, Polok K, Włudarczyk A, Górka J, Kozera N, Goździk W, Catorze N, Branco MC, Barros I, Barros N, Krystopchuk A, Honrado T, Sousa C, Munoz F, Rebelo M, Gomes R, Nunes J, Dias C, Fernandes AM, Petrisor C, Constantin B, Belskiy V, Boskholov B, Rodriguez E, Rebollo S, Aguilar G, Masdeu G, Jaimes MI, Mira ÁP, Bodi MA, Barea Mendoza JA, López-Cuenca S, Guzman MH, Rico-Feijoo J, Ibarz M, Alvarez JT, Kawati R, Sivik J, Nauska J, Smole D, Parenmark F, Lyrén J, Rockstrohm K, Rydén S, Spångfors M, Strinnholm M, Walther S, De Geer L, Nordlund P, Pålsson S, Zetterquist H, Nilsson A, Thiringer K, Jungner M, Bark B, Nordling B, Sköld H, Brorsson C, Persson S, Bergström A, Berkius J, Holmström J, van Dijk I, Haas LEM, Ramnarain D, Jansen T, Nooteboom F, van der Voort PHJ, de Lange D, Dieperink W, de Waard MC, de Smet AGE, Bormans L, Dormans T, Dempsey G, Mathew SJ, Raj AS, Grecu I, Cupitt J, Lawton T, Clark R, Popescu M, Spittle N, Faulkner M, Cowton A, Elloway E, Williams P, Reay M, Chukkambotla S, Kumar R, Al-Subaie N, Kent L, Tamm T, Kajtor I, Burns K, Pugh R, Ostermann M, Kam E, Bowyer H, Smith N, Templeton M, Henning J, Goffin K, Kapoor R, Laha S, Chilton P, Khaliq W, Crayford A, Coetzee S, Tait M, Stoker W, Gimenez M, Pope A, Camsooksai J, Pogson D, Quigley K, Ritzema J, Hormis A, Boulanger C, Balasubramaniam M, Vamplew L, Burt K, Martin D, Grecu I, Craig J, Prowle J, Doyle N, Shelton J, Scott C, Donnison P, Shelton S, Frey C, Ryan C, Spray D, Ryan C, Barnes V, Barnes K, Ridgway S, Saha R, Kent L, Clark T, Wood J, Bolger C, Bassford C, Cowton A, Lewandowski J, Zhao X, Humphreys S, Dowling S, Richardson N, Burtenshaw A, Stevenson C, Wilcock D, Nalapko Y., Critical Care, and Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE)
Subjects: INTENSIVE-CARE-UNIT, Survival, HSJ UCI, Critical Care and Intensive Care Medicine, survival analysis, law.invention, sepsis, Severity of illne, 0302 clinical medicine, LONG-TERM OUTCOMES, overlevingsanalyse, law, Medicine and Health Sciences, EPIDEMIOLOGY, Intensive care, Mortality, Outcome, Sepsis, Severity of illness, Very old, 030212 general & internal medicine, Prospective cohort study, ELDERLY-PATIENTS, ddc:617, PATIENTS AGED 80, lcsh:Medical emergencies. Critical care. Intensive care. First aid, Very Old, Intensive care unit, SOFA score, medicine.symptom, CRITICALLY-ILL PATIENTS, WITHDRAWAL, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, Sepsi, elderly patients, NO, 03 medical and health sciences, sterfte, Internal medicine, medicine, FRAILTY, business.industry, Septic shock, Research, SEPTIC SHOCK, Organ dysfunction, Intensive Care, 030208 emergency & critical care medicine, lcsh:RC86-88.9, oudere patiënten, medicine.disease, business
Abstract: BackgroundThe number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. Sepsis incidence has risen in recent years and identification of outcomes is of considerable public importance. We aimed to determine whether VIPs admitted for sepsis had different outcomes than those admitted for other acute reasons and identify potential prognostic factors for 30-day survival.ResultsThis prospective study included VIPs with Sequential Organ Failure Assessment (SOFA) scores ≥ 2 acutely admitted to 307 ICUs in 21 European countries. Of 3869 acutely admitted VIPs, 493 (12.7%) [53.8% male, median age 83 (81–86) years] were admitted for sepsis. Sepsis was defined according to clinical criteria; suspected or demonstrated focus of infection and SOFA score ≥ 2 points. Compared to VIPs admitted for other acute reasons, VIPs admitted for sepsis were younger, had a higher SOFA score (9 vs. 7,p p p p = 0.02]. Frailty was similar in both groups. Unadjusted 30-day survival was not significantly different between the two groups. After adjustment for age, gender, frailty, and SOFA score, sepsis had no impact on 30-day survival [HR 0.99 (95% CI 0.86–1.15),p = 0.917]. Inverse-probability weight (IPW)-adjusted survival curves for the first 30 days after ICU admission were similar for acute septic and non-septic patients [HR: 1.00 (95% CI 0.87–1.17),p = 0.95]. A matched-pair analysis in which patients with sepsis were matched with two control patients of the same gender with the same age, SOFA score, and level of frailty was also performed. A Cox proportional hazard regression model stratified on the matched pairs showed that 30-day survival was similar in both groups [57.2% (95% CI 52.7–60.7) vs. 57.1% (95% CI 53.7–60.1),p = 0.85].ConclusionsAfter adjusting for organ dysfunction, sepsis at admission was not independently associated with decreased 30-day survival in this multinational study of 3869 VIPs. Age, frailty, and SOFA score were independently associated with survival.
Published: 2020

25. Ubiquitin‐specific peptidase 2 as a potential link between microRNA‐125b and psoriasis

Author: Wei, T., Folkersen, L., Biskup, E., Xu, N., Manfe, V., Niazi, O., and Gniadecki, R.
Published: 2017
Full Text: View/download PDF

26. P.0010 Psychiatry trainees’ attitudes, knowledge and training in addiction psychiatry - a European survey

Author: Orsolini, L., primary, Palavra, I. Rojnić, additional, Papanti, G.D., additional, Potočan, M., additional, Quattrone, D., additional, Martens, M., additional, Sklenářová, S., additional, Levola, J., additional, Grichy, L., additional, Naughton, S., additional, Grinevičienė, I.K., additional, Kuiters, J.P., additional, Gondek, T.M., additional, Panfil, A.L., additional, Borovcanin, M., additional, Uria, A. San Roman, additional, Biskup, E., additional, Sönmez, E., additional, Dias, M.C., additional, Tomori, S., additional, Banjac, V., additional, Marinova-Djambazova, P., additional, and Da Costa, M. Pinto, additional
Published: 2021
Full Text: View/download PDF

27. a prospective cohort study

Author: Fronczek, Jakub, Polok, Kamil, de Lange, Dylan W., Jung, Christian, Beil, Michael, Rhodes, Andrew, Fjølner, J., Górka, Jacek, Andersen, Finn H., Artigas, Antonio, Cecconi, Maurizio, Christensen, Steffen, Joannidis, Michael, Leaver, Susannah, Marsh, Brian, Morandi, Alessandro, Moreno, Rui, Oeyen, S., Agvald-Öhman, Christina, Bollen Pinto, B., Schefold, J. C., Valentin, Andreas, Walther, Sten, Watson, Ximena, Zafeiridis, Tilemachos, Sviri, Sigal, van Heerden, Peter Vernon, Flaatten, Hans, Guidet, Bertrand, Szczeklik, Wojciech, Schmutz, R., Wimmer, F., Eller, P., Joannidis, M., De Buysscher, P., De Neve, N., Swinnen, W., Abraham, P., Hergafi, L., Biskup, E., Piza, P., Taliadoros, I., Dey, N., Sølling, C., Rasmussen, B. S., Ferreira, I. A., and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Subjects: Intensive care units, Frailty, Aged, 80 and over, Mortality, Critical Care and Intensive Care Medicine, Prospective studies
Abstract: Funding Information: The members of VIP1 and VIP2 study groups are listed in Additional file 1 and are listed in their individual PubMed records. Publisher Copyright: © 2021, The Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved. Background: The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic value of frailty in this context. Methods: We analysed data from two multicentre prospective cohort studies which enrolled intensive care unit patients ≥ 80 years old in 26 countries. The primary outcome was mortality within 30-days from admission to the ICU. Logistic regression models for both ICU and 30-day mortality included the CFS score as either a categorical, continuous or dichotomous variable and were adjusted for patient’s age, sex, reason for admission to the ICU, and admission Sequential Organ Failure Assessment score. Results: The median age in the sample of 7487 consecutive patients was 84 years (IQR 81–87). The highest fraction of new prognostic information from frailty in the context of 30-day mortality was observed when the CFS score was treated as either a categorical variable using all original levels of frailty or a nonlinear continuous variable and was equal to 9% using these modelling approaches (p < 0.001). The relationship between the CFS score and mortality was nonlinear (p < 0.01). Conclusion: Knowledge about a patient’s frailty status adds a substantial amount of new prognostic information at the moment of admission to the ICU. Arbitrary simplification of the CFS score into fewer groups than originally intended leads to a loss of information and should be avoided. Trial registration NCT03134807 (VIP1), NCT03370692 (VIP2) publishersversion published
Published: 2021

28. Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study

Author: Fronczek, Jakub, Polok, Kamil, de Lange, Dylan W., Jung, Christian, Beil, Michael, Rhodes, Andrew, Fjølner, Jesper, Górka, Jacek, Andersen, Finn H., Artigas, Antonio, Cecconi, Maurizio, Christensen, Steffen, Joannidis, Michael, Leaver, Susannah, Marsh, Brian, Morandi, Alessandro, Moreno, Rui, Oeyen, Sandra, Agvald-Öhman, Christina, Bollen Pinto, Bernardo, Schefold, Joerg C., Valentin, Andreas, Walther, Sten, Watson, Ximena, Zafeiridis, Tilemachos, Sviri, Sigal, van Heerden, Peter Vernon, Flaatten, Hans, Guidet, Bertrand, Szczeklik, Wojciech, Schmutz, R., Wimmer, F., Eller, P., Joannidis, M., De Buysscher, P., De Neve, N., Oeyen, S., Swinnen, W., Bollen Pinto, B., Abraham, P., Hergafi, L., Schefold, J. C., Biskup, E., Piza, P., Taliadoros, I., Fjølner, J., Dey, N., Sølling, C., Rasmussen, B. S., Christensen, S., Forceville, X., Besch, G., Mentec, H., Michel, P., Mateu, P., Vettoretti, L., Bourenne, J., Marin, N., Guillot, M., Aissaoui, N., Goulenok, C., Thieulot-Rolin, N., Messika, J., Lamhaut, L., Guidet, B., Charron, C., Lauten, A., Sacher, A. L., Brenner, T., Franz, M., Bloos, F., Ebelt, H., Schaller, S. J., Fuest, K., Rabe, C., Dieck, T., Steiner, S., Graf, T., Nia, A. M., Jung, C., Janosi, R. A., Meybohm, P., Simon, P., Utzolino, S., Rahmel, T., Barth, E., Schuster, M., Aidoni, Z., Aloizos, S., Tasioudis, P., Lampiri, K., Zisopoulou, V., Ravani, I., Pagaki, E., Antoniou, A., Katsoulas, T. A., Kounougeri, A., Marinakis, G., Tsimpoukas, F., Spyropoulou, A., Zygoulis, P., Kyparissi, A., Gupta, M., Gurjar, M., Maji, I. M., Hayes, I., Marsh, B., Kelly, Y., Westbrook, A., Fitzpatrick, G., Maheshwari, D., Motherway, C., Negri, G., Spadaro, S., Nattino, G., Pedeferri, M., Boscolo, A., Rossi, S., Calicchio, G., Cubattoli, L., Di Lascio, G., Barbagallo, M., Berruto, F., Codazzi, D., Bottazzi, A., Fumagalli, P., Negro, G., Lupi, G., Savelli, F., Vulcano, G. A., Fumagalli, R., Marudi, A., Lefons, U., Lembo, R., Babini, M., Paggioro, A., Parrini, V., Zaccaria, M., Clementi, S., Gigliuto, C., Facondini, F., Pastorini, S., Munaron, S., Calamai, I., Bocchi, A., Adorni, A., Bocci, M. G., Cortegiani, A., Casalicchio, T., Mellea, S., Graziani, E., Barattini, M., Brizio, E., Rossi, M., Hahn, M., Flaatten, H., Kemmerer, N., Strietzel, H. F., Dybwik, K., Legernaes, T., Klepstad, P., Olaussen, E. B., Olsen, K. I., Brresen, O. M., Bjorsvik, G., Andersen, F. H., Maini, S., Fehrle, L., Czuczwar, M., Krawczyk, P., Ziętkiewicz, M., Nowak, Ł. R., Kotfis, K., Cwyl, K., Gajdosz, R., Biernawska, J., Bohatyrewicz, R., Gawda, R., Grudzień, P., Nasiłowski, P., Popek, N., Cyrankiewicz, W., Wawrzyniak, K., Wnuk, M., Maciejewski, D., Studzińska, D., Żukowski, M., Bernas, S., Piechota, M., Szczeklik, W., Nowak-Kózka, I., Fronczek, J., Serwa, M., Machała, W., Stefaniak, J., Wujtewicz, M., Maciejewski, P., Szymkowiak, M., Adamik, B., Polok, K., Górka, J., Catorze, N., Branco, M. C., Barros, N., Barros, I., Krystopchuk, A., Honrado, T., Sousa, C., Munoz, F., Rebelo, M., Gomes, R., Nunes, J., Dias, C., Fernandes, A. M., Petrisor, C., Constantin, B., Belskiy, V., Boskholov, B., Rodriguez, E., Aguilar, G., Masdeu, G., Jaimes, M. I., Mira, A. P., Bodi, M. A., Mendoza, J. A. B., López-Cuenca, S., Guzman, M. H., Rico-Feijoo, J., Ibarz, M., Alvarez, J. Trenado, Kawati, R., Sivik, J., Nauska, J., Smole, D., Parenmark, F., Lyrén, J., Rockstroh, K., Rydén, S., Spångfors, M., Strinnholm, M., Walther, S., De Geer, L., Nordlund, P., Pålsson, S., Zetterquist, H., Nilsson, A., Thiringer, K., Jungner, M., Bark, B., Nordling, B., Sköld, H., Brorsson, C., Persson, S., Bergström, A., Berkius, J., Holmström, J., van Dijk, I., van Lelyveld-Haas, L. E. M., Jansen, T., Nooteboom, F., van der Voort, P. H. J., de Lange, D., Dieperink, W., de Waard, M. C., de Smet, A. G. E., Bormans, L., Dormans, T., Dempsey, G., Mathew, S. J., Raj, A. S., Grecu, I., Cupitt, J., Lawton, T., Clark, R., Popescu, M., Spittle, N., Faulkner, M., Cowton, A., Williams, P., Elloway, E., Reay, M., Chukkambotla, S., Kumar, R., Al-Subaie, N., Kent, L., Tamm, T., Kajtor, I., Burns, K., Pugh, R., Ostermann, M., Kam, E., Bowyer, H., Smith, N., Templeton, M., Henning, J., Goffin, K., Kapoor, R., Laha, S., Chilton, P., Khaliq, W., Crayford, A., Coetzee, S., Tait, M., Stoker, W., Gimenez, M., Pope, A., Camsooksai, J., Pogson, D., Quigley, K., Ritzema, J., Hormis, A., Boulanger, C., Balasubramaniam, M., Vamplew, L., Burt, K., Martin, D., Craig, J., Prowle, J., Doyle, N., Shelton, J., Scott, C., Donnison, P., Shelton, S., Frey, C., Ryan, C., Spray, D., Barnes, V., Barnes, K., Ridgway, S., Saha, R., Clark, T., Wood, J., Bolger, C., Bassford, C., Lewandowski, J., Zhao, X., Humphreys, S., Dowling, S., Richardson, N., Burtenshaw, A., Stevenson, C., Wilcock, D., Nalapko, Y., Helbok, R., Nollet, J., de Neve, N., Mikačić, M., Bastiansen, A., Husted, A., Dahle, B. E. S., Cramer, C., Ørsnes, D., Thomsen, J. Edelberg, Pedersen, J. J., Enevoldsen, M. Hummelmose, Elkmann, T., Kubisz-Pudelko, A., Collins, A., Hart, C., Randell, G., Filipe, H., Welters, I. D., Evans, J., Lord, J., Jones, J., Ball, J., North, J., Salaunkey, K., De Gordoa, L. Ortiz-Ruiz, Bell, L., Vizcaychipi, M., Mupudzi, M., Lea-Hagerty, M., Spivey, M., Love, N., White, N., Morgan, P., Wakefield, P., Savine, R., Jacob, R., Innes, R., Rose, S., Leaver, S., Mane, T., Ogbeide, V., Baird, Y., Romen, A., Galbois, A., Vinsonneau, C., Thevenin, D., Guerot, E., Savary, G., Chagnon, J. L., Rigaud, J. P., Quenot, J. P., Castaneray, J., Rosman, J., Maizel, J., Tiercelet, K., Hovaere, M. M., Messika, M., Djibré, M., Rolin, N., Burtin, P., Garcon, P., Nseir, S., Valette, X., Horacek, M., Bruno, R. Romano, Allgäuer, S., Dubler, S., Schering, S., Koutsikou, A., Vakalos, A., Raitsiou, B., Flioni, E. N., Neou, E., Papathanakos, G., Koutsodimitropoulos, I., Aikaterini, K., Rovina, N., Kourelea, S., Polychronis, T., Zidianakis, V., Konstantinia, V., Read, C., Martin-Loeches, I., Cracchiolo, A. Neville, Morigi, A., Brusa, S., Elhadi, A., Tarek, A., Khaled, A., Ahmed, H., Belkhair, W. Ali, Cornet, A. D., Gommers, D., van Boven, E., Haringman, J., Haas, L., van den Berg, L., Hoiting, O., de Jager, P., Gerritsen, R. T., Breidablik, A., Slapgard, A., Rime, A. K., Jannestad, B., Sjøbøe, B., Rice, E., Jensen, J. P., Langørgen, J., Tøien, K., Strand, K., Biernacka, A., Kluzik, A., Kudlinski, B., Hymczak, H., Solek-Pastuszka, J., Zorska, J., Krzych, Ł. J., Zukowski, M., Lipińska-Gediga, M., Pietruszko, M., Kozera, N., Sendur, P., Zatorski, P., Galkin, P., Kościuczuk, U., Gola, W., Pinto, A. F., Santos, A. R., Ferreira, I. A., Blanco, J. B., Carvalho, J. T., Maia, J., Candeias, N., Lores, A., Cilloniz, C., Perez-Torres, D., Maseda, E., Prol-Silva, E., Eixarch, G., Gomà, G., Velasco, G. Navarro, Jaimes, M. Irazábal, Villamayor, M. Ibarz, Fernández, N. Llamas, Cubero, P. Jimeno, Tomasa, T., Sjöqvist, A., Schiöler, F., Westberg, H., Thiringer, K. Kleiven, Boroli, F., Eckert, P., Yıldız, I., Yovenko, I., for the VIP1, [missing], VIP2 study group, [missing], Fronczek, Jakub, Polok, Kamil, de Lange, Dylan W, Jung, Christian, Beil, Michael, Rhodes, Andrew, Fjølner, Jesper, Górka, Jacek, Andersen, Finn H, Artigas, Antonio, Cecconi, Maurizio, Christensen, Steffen, Joannidis, Michael, Leaver, Susannah, Marsh, Brian, Morandi, Alessandro, Moreno, Rui, Oeyen, Sandra, Agvald-Öhman, Christina, Bollen Pinto, Bernardo, Schefold, Joerg C, Valentin, Andrea, Walther, Sten, Watson, Ximena, Zafeiridis, Tilemacho, Sviri, Sigal, van Heerden, Peter Vernon, Flaatten, Han, Guidet, Bertrand, Szczeklik, Wojciech, R Schmutz, F Wimmer, P Eller, M Joannidis, P De Buysscher, N De Neve, S Oeyen, W Swinnen, B Bollen Pinto, P Abraham, L Hergafi, J C Schefold, E Biskup, P Piza, I Taliadoros, J Fjølner, N Dey, C Sølling, B S Rasmussen, S Christensen, X Forceville, G Besch, H Mentec, P Michel, P Mateu, P Michel, L Vettoretti, J Bourenne, N Marin, M Guillot, N Aissaoui, C Goulenok, N Thieulot-Rolin, J Messika, L Lamhaut, B Guidet, C Charron, A Lauten, A L Sacher, T Brenner, M Franz, F Bloos, H Ebelt, S J Schaller, K Fuest, C Rabe, T Dieck, S Steiner, T Graf, A M Nia, C Jung, R A Janosi, P Meybohm, P Simon, S Utzolino, T Rahmel, E Barth, C Jung, M Schuster, Z Aidoni, S Aloizos, P Tasioudis, K Lampiri, V Zisopoulou, I Ravani, E Pagaki, A Antoniou, T A Katsoulas, A Kounougeri, G Marinakis, F Tsimpoukas, A Spyropoulou, P Zygoulis, A Kyparissi, M Gupta, M Gurjar, I M Maji, I Hayes, B Marsh, Y Kelly, A Westbrook, G Fitzpatrick, D Maheshwari, C Motherway, G Negri, S Spadaro, G Nattino, M Pedeferri, A Boscolo, S Rossi, G Calicchio, L Cubattoli, G Di Lascio, M Barbagallo, F Berruto, D Codazzi, A Bottazzi, P Fumagalli, G Negro, G Lupi, F Savelli, G A Vulcano, R Fumagalli, A Marudi, U Lefons, R Lembo, M Babini, A Paggioro, V Parrini, M Zaccaria, S Clementi, C Gigliuto, F Facondini, S Pastorini, S Munaron, I Calamai, A Bocchi, A Adorni, M G Bocci, A Cortegiani, T Casalicchio, S Mellea, E Graziani, M Barattini, E Brizio, M Rossi, M Hahn, H Flaatten, N Kemmerer, H F Strietzel, K Dybwik, T Legernaes, P Klepstad, E B Olaussen, K I Olsen, O M Brresen, G Bjorsvik, F H Andersen, S Maini, L Fehrle, M Czuczwar, P Krawczyk, M Ziętkiewicz, Ł R Nowak, K Kotfis, K Cwyl, R Gajdosz, J Biernawska, R Bohatyrewicz, R Gawda, P Grudzień, P Nasiłowski, N Popek, W Cyrankiewicz, K Wawrzyniak, M Wnuk, D Maciejewski, D Studzińska, M Żukowski, S Bernas, M Piechota, W Szczeklik, I Nowak-Kózka, J Fronczek, M Serwa, W Machała, J Stefaniak, M Wujtewicz, P Maciejewski, M Szymkowiak, B Adamik, K Polok, J Górka, N Catorze, M C Branco, N Barros, I Barros, A Krystopchuk, T Honrado, C Sousa, F Munoz, M Rebelo, R Gomes, J Nunes, C Dias, A M Fernandes, C Petrisor, B Constantin, V Belskiy, B Boskholov, E Rodriguez, G Aguilar, G Masdeu, M I Jaimes, A P Mira, M A Bodi, J A B Mendoza, S López-Cuenca, M H Guzman, J Rico-Feijoo, M Ibarz, J Trenado Alvarez, R Kawati, J Sivik, J Nauska, D Smole, F Parenmark, J Lyrén, K Rockstroh, S Rydén, M Spångfors, M Strinnholm, S Walther, L De Geer, P Nordlund, S Pålsson, H Zetterquist, A Nilsson, K Thiringer, M Jungner, B Bark, B Nordling, H Sköld, C Brorsson, S Persson, A Bergström, J Berkius, J Holmström, I van Dijk, L E M van Lelyveld-Haas, T Jansen, F Nooteboom, P H J van der Voort, D de Lange, W Dieperink, M C de Waard, A G E de Smet, L Bormans, T Dormans, G Dempsey, S J Mathew, A S Raj, I Grecu, J Cupitt, T Lawton, R Clark, M Popescu, N Spittle, M Faulkner, A Cowton, P Williams, E Elloway, M Reay, S Chukkambotla, R Kumar, N Al-Subaie, L Kent, T Tamm, I Kajtor, K Burns, R Pugh, M Ostermann, E Kam, H Bowyer, N Smith, M Templeton, J Henning, K Goffin, R Kapoor, S Laha, P Chilton, W Khaliq, A Crayford, S Coetzee, M Tait, W Stoker, M Gimenez, A Pope, J Camsooksai, D Pogson, K Quigley, J Ritzema, A Hormis, C Boulanger, M Balasubramaniam, L Vamplew, K Burt, D Martin, I Grecu, J Craig, J Prowle, N Doyle, J Shelton, C Scott, P Donnison, S Shelton, C Frey, C Ryan, D Spray, C Ryan, V Barnes, K Barnes, S Ridgway, R Saha, L Kent, T Clark, J Wood, C Bolger, C Bassford, A Cowton, J Lewandowski, X Zhao, S Humphreys, S Dowling, N Richardson, A Burtenshaw, C Stevenson, D Wilcock, Y Nalapko, M Joannidis, P Eller, R Helbok, R Schmutz, J Nollet, N de Neve, P De Buysscher, S Oeyen, W Swinnen, M Mikačić, A Bastiansen, A Husted, B E S Dahle, C Cramer, C Sølling, D Ørsnes, J Edelberg Thomsen, J J Pedersen, M Hummelmose Enevoldsen, T Elkmann, A Kubisz-Pudelko, A Pope, A Collins, A S Raj, C Boulanger, C Frey, C Hart, C Bolger, D Spray, G Randell, H Filipe, I D Welters, I Grecu, J Evans, J Cupitt, J Lord, J Henning, J Jones, J Ball, J North, K Salaunkey, L Ortiz-Ruiz De Gordoa, L Bell, M Balasubramaniam, M Vizcaychipi, M Faulkner, M Mupudzi, M Lea-Hagerty, M Reay, M Spivey, N Love, N Spittle, N White, P Williams, P Morgan, P Wakefield, R Savine, R Jacob, R Innes, R Kapoor, S Humphreys, S Rose, S Dowling, S Leaver, T Mane, T Lawton, V Ogbeide, W Khaliq, Y Baird, A Romen, A Galbois, B Guidet, C Vinsonneau, C Charron, D Thevenin, E Guerot, G Besch, G Savary, H Mentec, J L Chagnon, J P Rigaud, J P Quenot, J Castaneray, J Rosman, J Maizel, K Tiercelet, L Vettoretti, M M Hovaere, M Messika, M Djibré, N Rolin, P Burtin, P Garcon, S Nseir, X Valette, C Rabe, E Barth, H Ebelt, K Fuest, M Franz, M Horacek, M Schuster, P Meybohm, R Romano Bruno, S Allgäuer, S Dubler, S J Schaller, S Schering, S Steiner, T Dieck, T Rahmel, T Graf, A Koutsikou, A Vakalos, B Raitsiou, E N Flioni, E Neou, F Tsimpoukas, G Papathanakos, G Marinakis, I Koutsodimitropoulos, K Aikaterini, N Rovina, S Kourelea, T Polychronis, V Zidianakis, V Konstantinia, Z Aidoni, B Marsh, C Motherway, C Read, I Martin-Loeches, A Neville Cracchiolo, A Morigi, I Calamai, S Brusa, A Elhadi, A Tarek, A Khaled, H Ahmed, W Ali Belkhair, A D Cornet, D Gommers, D de Lange, E van Boven, J Haringman, L Haas, L van den Berg, O Hoiting, P de Jager, R T Gerritsen, T Dormans, W Dieperink, A Breidablik, A Slapgard, A K Rime, B Jannestad, B Sjøbøe, E Rice, F H Andersen, H F Strietzel, J P Jensen, J Langørgen, K Tøien, K Strand, M Hahn, P Klepstad, A Biernacka, A Kluzik, B Kudlinski, D Maciejewski, D Studzińska, H Hymczak, J Stefaniak, J Solek-Pastuszka, J Zorska, K Cwyl, Ł J Krzych, M Zukowski, M Lipińska-Gediga, M Pietruszko, M Piechota, M Serwa, M Czuczwar, M Ziętkiewicz, N Kozera, P Nasiłowski, P Sendur, P Zatorski, P Galkin, R Gawda, U Kościuczuk, W Cyrankiewicz, W Gola, A F Pinto, A M Fernandes, A R Santos, C Sousa, I Barros, I A Ferreira, J B Blanco, J T Carvalho, J Maia, N Candeias, N Catorze, V Belskiy, A Lores, A P Mira, C Cilloniz, D Perez-Torres, E Maseda, E Rodriguez, E Prol-Silva, G Eixarch, G Gomà, G Aguilar, G Navarro Velasco, M Irazábal Jaimes, M Ibarz Villamayor, N Llamas Fernández, P Jimeno Cubero, S López-Cuenca, T Tomasa, A Sjöqvist, C Brorsson, F Schiöler, H Westberg, J Nauska, J Sivik, J Berkius, K Kleiven Thiringer, L De Geer, S Walther, F Boroli, J C Schefold, L Hergafi, P Eckert, I Yıldız, I Yovenko, Y Nalapko, R Pugh, and Critical Care
Subjects: Male, Short term mortality, Critical Care and Intensive Care Medicine, Cohort Studies, 0302 clinical medicine, kwetsbaarheid, Medicine and Health Sciences, 80 and over, Medicine, 610 Medicine & health, Prospective cohort study, Correlation of Data, 11 Medical and Health Sciences, Aged, 80 and over, OUTCOMES, Intensive care units, Frailty, VIP1, Aged,&nbsp, Medical emergencies. Critical care. Intensive care. First aid, Scale (social sciences), Female, prospectief onderzoek, Life Sciences & Biomedicine, CRITICALLY-ILL PATIENTS, Study groups, medicine.medical_specialty, Anestesi och intensivvård, 80 jaar en ouder, INTENSIVE-CARE, BED AVAILABILITY, NO, 03 medical and health sciences, Critical Care Medicine, Intensive care, sterfte, General & Internal Medicine, Humans, Aged, Prospective studies, Mortality, In patient, ddc:610, Intensive Care Units, Logistic Models, Prospective Studies, Science & Technology, Anesthesiology and Intensive Care, business.industry, RC86-88.9, Research, 030208 emergency & critical care medicine, ADULTS, Aged, 80 and over, Emergency & Critical Care Medicine, 030228 respiratory system, intensivecareafdelingen, Critical illness, Emergency medicine, VIP2 study group, &nbsp, CRITICAL ILLNESS, business
Abstract: Background The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after admission to the ICU. This study aimed to evaluate the influence of modelling approach on the association between the CFS score and short-term mortality and quantify the prognostic value of frailty in this context. Methods We analysed data from two multicentre prospective cohort studies which enrolled intensive care unit patients ≥ 80 years old in 26 countries. The primary outcome was mortality within 30-days from admission to the ICU. Logistic regression models for both ICU and 30-day mortality included the CFS score as either a categorical, continuous or dichotomous variable and were adjusted for patient’s age, sex, reason for admission to the ICU, and admission Sequential Organ Failure Assessment score. Results The median age in the sample of 7487 consecutive patients was 84 years (IQR 81–87). The highest fraction of new prognostic information from frailty in the context of 30-day mortality was observed when the CFS score was treated as either a categorical variable using all original levels of frailty or a nonlinear continuous variable and was equal to 9% using these modelling approaches (p p Conclusion Knowledge about a patient’s frailty status adds a substantial amount of new prognostic information at the moment of admission to the ICU. Arbitrary simplification of the CFS score into fewer groups than originally intended leads to a loss of information and should be avoided. Trial registration NCT03134807 (VIP1), NCT03370692 (VIP2)
Published: 2021

29. Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU

Author: de Lange D. W., Brinkman S., Flaatten H., Boumendil A., Morandi A., Andersen F. H., Artigas A., Bertolini G., Cecconi M., Christensen S., Faraldi L., Fjolner J., Jung C., Marsh B., Moreno R., Oeyen S., Ohman C. A., Bollen Pinto B., de Smet A. M. G. A., Soliman I. W., Szczeklik W., Valentin A., Watson X., Zafeiridis T., Guidet B., Schmutz R., Wimmer F., Eller P., Joannidis M., De Buysscher P., De Neve N., Swinnen W., Abraham P., Hergafi L., Schefold Joerg. C., Biskup E., Piza P., Taliadoros I., Dey N., Solling C., Rasmussen B. S., Forceville X., Besch G., Mentec H., Michel P., Mateu P., Vettoretti L., Bourenne J., Marin N., Guillot M., Aissaoui N., Goulenok C., Thieulot-Rolin N., Messika J., Lamhaut L., Charron C., Lauten A., Sacher A. L., Brenner T., Franz M., Bloos F., Ebelt H., Schaller S. J., Fuest Kristina., Rabe C., Dieck T., Steiner S., Graf T., Nia A. M., Janosi R. A., Meybohm P., Simon P., Utzolino S., Rahmel T., Barth E., Schuster M., Aidoni Z., Aloizos S., Tasioudis P., Lampiri K., Zisopoulou V., Ravani I., Pagaki E., Antoniou A., Katsoulas T. A., Kounougeri A., Marinakis G., Tsimpoukas F., Spyropoulou A., Zygoulis P., Kyparissi A., Gupta M., Gurjar M., Maji I. M., Hayes I., Kelly Y., Westbrook A., Fitzpatrick G., Maheshwari D., Motherway C., Negri G., Spadaro S., Nattino G., Pedeferri M., Boscolo A., Rossi S., Calicchio G., Cubattoli L., Di Lascio G., Barbagallo M., Berruto F., Codazzi D., Bottazzi A., Fumagalli P., Negro G., Lupi G., Savelli F., Vulcano Giuseppe. A., Fumagalli R., Marudi A., Lefons U., Lembo R., Babini M., Paggioro A., Parrini V., Zaccaria M., Clementi S., Gigliuto C., Facondini F., Pastorini S., Munaron S., Calamai I., Bocchi A., Adorni A., Bocci M. G., Cortegiani A., Casalicchio T., Mellea S., Graziani E., Barattini M., Brizio E., Rossi M., Hahn M., Kemmerer N., Strietzel H. F., Dybwik K., Legernaes T., Klepstad P., Olaussen E. B., Olsen K. I., Brresen O. M., Bjorsvik G., Maini S., Fehrle L., Czuczwar M., Krawczyk P., Zietkiewicz M., Nowak L. R., Kotfis K., Cwyl K., Gajdosz R., Biernawska J., Bohatyrewicz Romuald., Gawda R., Grudzien P., Nasilowski P., Popek N., Cyrankiewicz W., Wawrzyniak K., Wnuk M., Maciejewski D., Studzinska D., Zukowski M., Bernas S., Piechota M., Nowak I., Fronczek J., Serwa M., Machala W., Stefaniak J., Wujtewicz M., Maciejewski P., Szymkowiak M., Adamik B., Catorze N., Branco M. C., Barros I., Barros N., Krystopchuk A., Honrado T., Sousa C., Munoz F., Rebelo M., Gomes R., Nunes J., Dias Celeste., Fernandes A. M., Petrisor C., Constantin B., Belskiy V., Boskholov B., Rodriguez E., Rebollo S., Aguilar G., Masdeu G., Jaimes M. I., Mira A. P., Bodi Maria. A., Mendoza J. A. B., Cuenca S. L., Guzman M. H., Rico-Feijoo J., Ibarz M., Alvarez J. T., Kawati R., Sivik J., Nauska J., Smole D., Parenmark F., Lyren J., Rockstroh K., Ryden S., Strinnholm M., Walther S., De Geer L., Nordlund P., Palsson S., Zetterquist H., Nilsson A., Thiringer K., Jungner M., Bark B., Nordling B., Skold H., Brorsson C., Persson S., Bergstrom A., Berkius J., Holmstrom J., van Dijk I., van Lelyveld-Haas L. E. M., Ramnarain D., Jansen T., Nooteboom F., van der Voort P. H. J., Dieperink W., de Waard M. C., Bormans L., Dormans Tom., Dempsey G., Mathew S. J., Raj A. S., Grecu I., Cupitt J., Lawton T., Clark R., Popescu M., Spittle N., Faulkner M., Cowton A., Elloway E., Williams P., Reay M., Chukkambotla S., Kumar R., Al-Subaie N., Kent L., Tamm T., Kajtor I., Burns K., Pugh R., Ostermann M., Kam E., Bowyer H., Smith N., Templeton M., Henning J., Goffin K., Kapoor R., Laha S., Chilton P., Khaliq W., Crayford A., Coetzee S., Tait M., Stoker W., Gimenez M., Pope A., Camsooksai J., Pogson D., Quigley K., Ritzema J., Hormis A., Boulanger C., Balasubramaniam M., Vamplew L., Burt K., Martin D., Craig J., Prowle J., Doyle N., Shelton J., Scott Carmen., Donnison P., Shelton S., Frey C., Ryan C., Spray D., Barnes V., Barnes K., Ridgway S., Saha R., Clark T., Wood J., Bolger C., Bassford C., Lewandowski J., Zhao X., Humphreys S., Dowling S., Richardson N., Burtenshaw A., Stevenson C., Wilcock D., Nalapko Y., Microbes in Health and Disease (MHD), Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Medical Informatics, APH - Methodology, APH - Quality of Care, de Lange, D, Brinkman, S, Flaatten, H, Boumendil, A, Morandi, A, Andersen, F, Artigas, A, Bertolini, G, Cecconi, M, Christensen, S, Faraldi, L, Fjolner, J, Jung, C, Marsh, B, Favarato, M, Oeyen, S, Ohman, C, Bollen Pinto, B, de Smet, A, Soliman, I, Szczeklik, W, Valentin, A, Watson, X, Zafeiridis, T, Guidet, B, Schmutz, R, Wimmer, F, Eller, P, Joannidis, M, De Buysscher, P, De Neve, N, Swinnen, W, Abraham, P, Hergafi, L, Schefold, J, Biskup, E, Piza, P, Taliadoros, I, Dey, N, Solling, C, Rasmussen, B, Forceville, X, Besch, G, Mentec, H, Michel, P, Mateu, P, Vettoretti, L, Bourenne, J, Marin, N, Guillot, M, Aissaoui, N, Goulenok, C, Thieulot-Rolin, N, Messika, J, Lamhaut, L, Charron, C, Lauten, A, Sacher, A, Brenner, T, Franz, M, Bloos, F, Ebelt, H, Schaller, S, Fuest, K, Rabe, C, Dieck, T, Steiner, S, Graf, T, Nia, A, Janosi, R, Meybohm, P, Simon, P, Utzolino, S, Rahmel, T, Barth, E, Schuster, M, Aidoni, Z, Aloizos, S, Tasioudis, P, Lampiri, K, Zisopoulou, V, Ravani, I, Pagaki, E, Antoniou, A, Katsoulas, T, Kounougeri, A, Marinakis, G, Tsimpoukas, F, Spyropoulou, A, Zygoulis, P, Kyparissi, A, Gupta, M, Gurjar, M, Maji, I, Hayes, I, Kelly, Y, Westbrook, A, Fitzpatrick, G, Maheshwari, D, Motherway, C, Negri, G, Spadaro, S, Nattino, G, Pedeferri, M, Boscolo, A, Rossi, S, Calicchio, G, Cubattoli, L, Di Lascio, G, Barbagallo, M, Berruto, F, Codazzi, D, Bottazzi, A, Fumagalli, P, Negro, G, Lupi, G, Savelli, F, Vulcano, G, Fumagalli, R, Marudi, A, Lefons, U, Lembo, R, Babini, M, Paggioro, A, Parrini, V, Zaccaria, M, Clementi, S, Gigliuto, C, Facondini, F, Pastorini, S, Munaron, S, Calamai, I, Bocchi, A, Adorni, A, Bocci, M, Cortegiani, A, Casalicchio, T, Mellea, S, Graziani, E, Barattini, M, Brizio, E, Rossi, M, Hahn, M, Kemmerer, N, Strietzel, H, Dybwik, K, Legernaes, T, Klepstad, P, Olaussen, E, Olsen, K, Brresen, O, Bjorsvik, G, Maini, S, Fehrle, L, Czuczwar, M, Krawczyk, P, Zietkiewicz, M, Nowak, L, Kotfis, K, Cwyl, K, Gajdosz, R, Biernawska, J, Bohatyrewicz, R, Gawda, R, Grudzien, P, Nasilowski, P, Popek, N, Cyrankiewicz, W, Wawrzyniak, K, Wnuk, M, Maciejewski, D, Studzinska, D, Zukowski, M, Bernas, S, Piechota, M, Nowak, I, Fronczek, J, Serwa, M, Machala, W, Stefaniak, J, Wujtewicz, M, Maciejewski, P, Szymkowiak, M, Adamik, B, Catorze, N, Branco, M, Barros, I, Barros, N, Krystopchuk, A, Honrado, T, Sousa, C, Munoz, F, Rebelo, M, Gomes, R, Nunes, J, Dias, C, Fernandes, A, Petrisor, C, Constantin, B, Belskiy, V, Boskholov, B, Rodriguez, E, Rebollo, S, Aguilar, G, Masdeu, G, Jaimes, M, Mira, A, Bodi, M, Mendoza, J, Cuenca, S, Guzman, M, Rico-Feijoo, J, Ibarz, M, Alvarez, J, Kawati, R, Sivik, J, Nauska, J, Smole, D, Parenmark, F, Lyren, J, Rockstroh, K, Ryden, S, Strinnholm, M, Walther, S, De Geer, L, Nordlund, P, Palsson, S, Zetterquist, H, Nilsson, A, Thiringer, K, Jungner, M, Bark, B, Nordling, B, Skold, H, Brorsson, C, Persson, S, Bergstrom, A, Berkius, J, Holmstrom, J, van Dijk, I, van Lelyveld-Haas, L, Ramnarain, D, Jansen, T, Nooteboom, F, van der Voort, P, Dieperink, W, de Waard, M, Bormans, L, Dormans, T, Dempsey, G, Mathew, S, Raj, A, Grecu, I, Cupitt, J, Lawton, T, Clark, R, Popescu, M, Spittle, N, Faulkner, M, Cowton, A, Elloway, E, Williams, P, Reay, M, Chukkambotla, S, Kumar, R, Al-Subaie, N, Kent, L, Tamm, T, Kajtor, I, Burns, K, Pugh, R, Ostermann, M, Kam, E, Bowyer, H, Smith, N, Templeton, M, Henning, J, Goffin, K, Kapoor, R, Laha, S, Chilton, P, Khaliq, W, Crayford, A, Coetzee, S, Tait, M, Stoker, W, Gimenez, M, Pope, A, Camsooksai, J, Pogson, D, Quigley, K, Ritzema, J, Hormis, A, Boulanger, C, Balasubramaniam, M, Vamplew, L, Burt, K, Martin, D, Craig, J, Prowle, J, Doyle, N, Shelton, J, Scott, C, Donnison, P, Shelton, S, Frey, C, Ryan, C, Spray, D, Barnes, V, Barnes, K, Ridgway, S, Saha, R, Clark, T, Wood, J, Bolger, C, Bassford, C, Lewandowski, J, Zhao, X, Humphreys, S, Dowling, S, Richardson, N, Burtenshaw, A, Stevenson, C, Wilcock, D, Nalapko, Y, de Lange D.W., Brinkman S., Flaatten H., Boumendil A., Morandi A., Andersen F.H., Artigas A., Bertolini G., Cecconi M., Christensen S., Faraldi L., Fjolner J., Jung C., Marsh B., Moreno R., Oeyen S., Ohman C.A., Bollen Pinto B., de Smet A.M.G.A., Soliman I.W., Szczeklik W., Valentin A., Watson X., Zafeiridis T., Guidet B., Schmutz R., Wimmer F., Eller P., Joannidis M., De Buysscher P., De Neve N., Swinnen W., Abraham P., Hergafi L., Schefold Joerg.C., Biskup E., Piza P., Taliadoros I., Dey N., Solling C., Rasmussen B.S., Forceville X., Besch G., Mentec H., Michel P., Mateu P., Vettoretti L., Bourenne J., Marin N., Guillot M., Aissaoui N., Goulenok C., Thieulot-Rolin N., Messika J., Lamhaut L., Charron C., Lauten A., Sacher A.L., Brenner T., Franz M., Bloos F., Ebelt H., Schaller S.J., Fuest Kristina., Rabe C., Dieck T., Steiner S., Graf T., Nia A.M., Janosi R.A., Meybohm P., Simon P., Utzolino S., Rahmel T., Barth E., Schuster M., Aidoni Z., Aloizos S., Tasioudis P., Lampiri K., Zisopoulou V., Ravani I., Pagaki E., Antoniou A., Katsoulas T.A., Kounougeri A., Marinakis G., Tsimpoukas F., Spyropoulou A., Zygoulis P., Kyparissi A., Gupta M., Gurjar M., Maji I.M., Hayes I., Kelly Y., Westbrook A., Fitzpatrick G., Maheshwari D., Motherway C., Negri G., Spadaro S., Nattino G., Pedeferri M., Boscolo A., Rossi S., Calicchio G., Cubattoli L., Di Lascio G., Barbagallo M., Berruto F., Codazzi D., Bottazzi A., Fumagalli P., Negro G., Lupi G., Savelli F., Vulcano Giuseppe.A., Fumagalli R., Marudi A., Lefons U., Lembo R., Babini M., Paggioro A., Parrini V., Zaccaria M., Clementi S., Gigliuto C., Facondini F., Pastorini S., Munaron S., Calamai I., Bocchi A., Adorni A., Bocci M.G., Cortegiani A., Casalicchio T., Mellea S., Graziani E., Barattini M., Brizio E., Rossi M., Hahn M., Kemmerer N., Strietzel H.F., Dybwik K., Legernaes T., Klepstad P., Olaussen E.B., Olsen K.I., Brresen O.M., Bjorsvik G., Maini S., Fehrle L., Czuczwar M., Krawczyk P., Zietkiewicz M., Nowak L.R., Kotfis K., Cwyl K., Gajdosz R., Biernawska J., Bohatyrewicz Romuald., Gawda R., Grudzien P., Nasilowski P., Popek N., Cyrankiewicz W., Wawrzyniak K., Wnuk M., Maciejewski D., Studzinska D., Zukowski M., Bernas S., Piechota M., Nowak I., Fronczek J., Serwa M., Machala W., Stefaniak J., Wujtewicz M., Maciejewski P., Szymkowiak M., Adamik B., Catorze N., Branco M.C., Barros I., Barros N., Krystopchuk A., Honrado T., Sousa C., Munoz F., Rebelo M., Gomes R., Nunes J., Dias Celeste., Fernandes A.M., Petrisor C., Constantin B., Belskiy V., Boskholov B., Rodriguez E., Rebollo S., Aguilar G., Masdeu G., Jaimes M.I., Mira A.P., Bodi Maria.A., Mendoza J.A.B., Cuenca S.L., Guzman M.H., Rico-Feijoo J., Ibarz M., Alvarez J.T., Kawati R., Sivik J., Nauska J., Smole D., Parenmark F., Lyren J., Rockstroh K., Ryden S., Strinnholm M., Walther S., De Geer L., Nordlund P., Palsson S., Zetterquist H., Nilsson A., Thiringer K., Jungner M., Bark B., Nordling B., Skold H., Brorsson C., Persson S., Bergstrom A., Berkius J., Holmstrom J., van Dijk I., van Lelyveld-Haas L.E.M., Ramnarain D., Jansen T., Nooteboom F., van der Voort P.H.J., Dieperink W., de Waard M.C., Bormans L., Dormans Tom., Dempsey G., Mathew S.J., Raj A.S., Grecu I., Cupitt J., Lawton T., Clark R., Popescu M., Spittle N., Faulkner M., Cowton A., Elloway E., Williams P., Reay M., Chukkambotla S., Kumar R., Al-Subaie N., Kent L., Tamm T., Kajtor I., Burns K., Pugh R., Ostermann M., Kam E., Bowyer H., Smith N., Templeton M., Henning J., Goffin K., Kapoor R., Laha S., Chilton P., Khaliq W., Crayford A., Coetzee S., Tait M., Stoker W., Gimenez M., Pope A., Camsooksai J., Pogson D., Quigley K., Ritzema J., Hormis A., Boulanger C., Balasubramaniam M., Vamplew L., Burt K., Martin D., Craig J., Prowle J., Doyle N., Shelton J., Scott Carmen., Donnison P., Shelton S., Frey C., Ryan C., Spray D., Barnes V., Barnes K., Ridgway S., Saha R., Clark T., Wood J., Bolger C., Bassford C., Lewandowski J., Zhao X., Humphreys S., Dowling S., Richardson N., Burtenshaw A., Stevenson C., Wilcock D., Nalapko Y., University Medical Center [Utrecht], University of Amsterdam [Amsterdam] (UvA), Public Health Service of Amsterdam, University of Bergen (UiB), Haukeland University Hospital, Service de Réanimation Médicale [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Norwegian University of Science and Technology [Trondheim] (NTNU), Norwegian University of Science and Technology (NTNU), Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Universitat Autònoma de Barcelona (UAB), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Aarhus University Hospital, Centro Hospitalar de Lisboa Central E.P.E, Ghent University Hospital, Karolinska University Hospital [Stockholm], Geneva University Hospital (HUG), University Medical Center Groningen [Groningen] (UMCG), Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), VIP1 Study Group (Beitragende*r), and Janosi, Rolf Alexander (Beitragende*r)
Subjects: Male, INTENSIVE-CARE-UNIT, Organ Dysfunction Scores, medicine.medical_treatment, Prognosis, Medizin, DECISION-MAKING, Logistic regression, law.invention, older adult, 0302 clinical medicine, PHYSICIANS, Interquartile range, law, 80 and over, Medicine and Health Sciences, 030212 general & internal medicine, Hospital Mortality, Prospective Studies, Prospective cohort study, older adults, Aged, 80 and over, predict, ddc:617, Respiration, [SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology, Brief Report, Intensive care unit, ADMISSION, 3. Good health, Europe, Hospitalization, Intensive Care Units, Brier score, Older adults, Artificial, Female, prognosi, medicine.medical_specialty, critical care, model, prognosis, Humans, Respiration, Artificial, 03 medical and health sciences, Intensive care, medicine, Journal Article, ILL ELDERLY-PATIENTS, Renal replacement therapy, Aged, Receiver operating characteristic, business.industry, 030208 emergency & critical care medicine, Emergency medicine, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Brief Reports, Geriatrics and Gerontology, business
Abstract: OBJECTIVES To develop a scoring system model that predicts mortality within 30 days of admission of patients older than 80 years admitted to intensive care units (ICUs). DESIGN Prospective cohort study. SETTING A total of 306 ICUs from 24 European countries. PARTICIPANTS Older adults admitted to European ICUs (N = 3730; median age = 84 years [interquartile range = 81‐87 y]; 51.8% male). MEASUREMENTS Overall, 24 variables available during ICU admission were included as potential predictive variables. Multivariable logistic regression was used to identify independent predictors of 30‐day mortality. Model sensitivity, specificity, and accuracy were evaluated with receiver operating characteristic curves. RESULTS The 30‐day‐mortality was 1562 (41.9%). In multivariable analysis, these variables were selected as independent predictors of mortality: age, sex, ICU admission diagnosis, Clinical Frailty Scale, Sequential Organ Failure Score, invasive mechanical ventilation, and renal replacement therapy. The discrimination, accuracy, and calibration of the model were good: the area under the curve for a score of 10 or higher was .80, and the Brier score was .18. At a cut point of 10 or higher (75% of all patients), the model predicts 30‐day mortality in 91.1% of all patients who die. CONCLUSION A predictive model of cumulative events predicts 30‐day mortality in patients older than 80 years admitted to ICUs. Future studies should include other potential predictor variables including functional status, presence of advance care plans, and assessment of each patient's decision‐making capacity. © 2019 The Authors. Journal of the American Geriatrics Society published by Wiley Periodicals, Inc. on behalf of The American Geriatrics Society. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Published: 2019

30. Correction to: Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit (Intensive Care Medicine, (2018), 44, 7, (1027-1038), 10.1007/s00134-018-5196-7)

Author: Guidet B., Flaatten H., Boumendil A., Morandi A., Andersen F. H., Artigas A., Bertolini G., Cecconi M., Christensen S., Faraldi L., Fjolner J., Jung C., Marsh B., Moreno R., Oeyen S., Ohman C. A., Pinto B. B., Soliman I. W., Szczeklik W., Valentin A., Watson X., Zafeiridis T., De Lange D. W., Schmutz R., Wimmer F., Eller P., Zotter K., De Buysscher P., De Neve N., Swinnen W., Taliadoros I., Piza P., Dey N., Solling C., Rasmussen B. S., Forceville X., Besch G., Mentec H., Michel P., Mateu P., Vettoretti L., Bourenne J., Marin N., Guillot M., Aissaoui N., Goulenok C., Thieulot-Rolin N., Messika J., Lamhaut L., Charron C., Lauten A., Sacher A. L., Brenner T., Franz M., Bloos F., Ebelt H., Schaller S. J., Fuest K., Rabe C., Dieck T., Steiner S., Graf T., Nia A. M., Janosi R. A., Simon P., Utzolino S., Rahmel T., Barth E., Schuster M., Meybohm P., Aidoni Z., Aloizos S., Tasioudis P., Lampiri K., Zisopoulou V., Ravani I., Pagaki E., Antoniou A., Katsoulas T. A., Kounougeri A., Marinakis G., Tsimpoukas F., Spyropoulou A., Zygoulis P., Kyparissi A., Gupta M., Gurjar M., Maji I. M., Hayes I., Kelly Y., Westbrook A., Fitzpatrick G., Maheshwari D., Motherway C., Negri G., Spadaro S., Nattino G., Pedeferri M., Boscolo A., Rossi S., Calicchio G., Cubattoli L., Di Lascio G., Barbagallo M., Berruto F., Codazzi D., Bottazzi A., Fumagalli P., Negro G., Lupi G., Savelli F., Vulcano G. A., Fumagalli R., Marudi A., Lefons U., Lembo R., Babini M., Paggioro A., Parrini V., Zaccaria M., Clementi S., Gigliuto C., Facondini F., Pastorini S., Munaron S., Calamai I., Bocchi A., Adorni A., Bocci M. G., Cortegiani A., Casalicchio T., Mellea S., Graziani E., Barattini M., Brizio E., Rossi M., Hahn M., Kemmerer N., Strietzel H. F., Dybwik K., Legernaes T., Klepstad P., Olaussen E. B., Olsen K. I., Brresen O. M., Bjorsvik G., Maini S., Fehrle L., Czuczwar M., Krawczyk P., Zietkiewicz M., Nowak L. R., Kotfis K., Cwyl K., Gajdosz R., Biernawska J., Bohatyrewicz R., Gawda R., Grudzien P., Nasilowski P., Popek N., Cyrankiewicz W., Wawrzyniak K., Wnuk M., Maciejewski D., Studzinska D., Zukowski M., Bernas S., Piechota M., Nowak I., Fronczek J., Serwa M., Machala W., Stefaniak J., Wujtewicz M., Maciejewski P., Szymkowiak M., Adamik B., Catorze N., Branco M. C., Barros I., Barros N., Krystopchuk A., Honrado T., Sousa C., Munoz F., Rebelo M., Gomes R., Nunes J., dias C., Fernandes A. M., Petrisor C., Constantin B., Belskiy V., Boskholov B., Rodriguez E., Rebollo S., Aguilar G., Masdeu G., Jaimes M. I., Mira A. P., Bodi M. A., Barea Mendoza J. A., Lopez-Cuenca S., Guzman M. H., Rico-Feijoo J., Ibarz M., Alvarez J. T., Kawati R., Sivik J., Nauska J., Smole D., Parenmark F., Lyren J., Rockstroh K., Ryden S., Spangfors M., Strinnholm M., Walther S., De Geer L., Nordlund P., Palsson S., Zetterquist H., Nilsson A., Thiringer K., Jungner M., Bark B., Nordling B., Skold H., Brorsson C., Persson S., Bergstrom A., Berkius J., Holmstrom J., Abraham P., Hergafi L., Schefold J. C., Biskup E., van Dijk I., van Lelyveld-Haas L. E. M., Ramnarain D., Jansen T., Nooteboom F., van der Voort P. H. J., de Lange D., Dieperink W., de Waard M. C., de Smet A. G., Bormans L., Dormans T., Dempsey G., Mathew S. J., Raj A. S., Grecu I., Cupitt J., Lawton T., Clark R., Popescu M., Spittle N., Faulkner M., Cowton A., Elloway E., Williams P., Reay M., Chukkambotla S., Kumar R., Al-Subaie N., Kent L., Tamm T., Kajtor I., Burns K., Pugh R., Ostermann M., Kam E., Bowyer H., Smith N., Templeton M., Henning J., Goffin K., Kapoor R., Laha S., Chilton P., Khaliq W., Crayford A., Coetzee S., Tait M., Stoker W., Gimenez M., Pope A., Camsooksai J., Pogson D., Quigley K., Ritzema J., Hormis A., Boulanger C., Balasubramaniam M., Vamplew L., Burt K., Martin D., Craig J., Prowle J., Doyle N., Shelton J., Scott C., Donnison P., Shelton S., Frey C., Ryan C., Spray D., Barnes V., Barnes K., Ridgway S., Saha R., Clark T., Wood J., Bolger C., Bassford C., lewandowski J., Zhao X., Humphreys S., Dowling S., Richardson N., Burtenshaw A., Stevenson C., Wilcock D., Nalapko Y., Guidet, B, Flaatten, H, Boumendil, A, Morandi, A, Andersen, F, Artigas, A, Bertolini, G, Cecconi, M, Christensen, S, Faraldi, L, Fjolner, J, Jung, C, Marsh, B, Moreno, R, Oeyen, S, Ohman, C, Pinto, B, Soliman, I, Szczeklik, W, Valentin, A, Watson, X, Zafeiridis, T, De Lange, D, Schmutz, R, Wimmer, F, Eller, P, Zotter, K, De Buysscher, P, De Neve, N, Swinnen, W, Taliadoros, I, Piza, P, Dey, N, Solling, C, Rasmussen, B, Forceville, X, Besch, G, Mentec, H, Michel, P, Mateu, P, Vettoretti, L, Bourenne, J, Marin, N, Guillot, M, Aissaoui, N, Goulenok, C, Thieulot-Rolin, N, Messika, J, Lamhaut, L, Charron, C, Lauten, A, Sacher, A, Brenner, T, Franz, M, Bloos, F, Ebelt, H, Schaller, S, Fuest, K, Rabe, C, Dieck, T, Steiner, S, Graf, T, Nia, A, Janosi, R, Simon, P, Utzolino, S, Rahmel, T, Barth, E, Schuster, M, Meybohm, P, Aidoni, Z, Aloizos, S, Tasioudis, P, Lampiri, K, Zisopoulou, V, Ravani, I, Pagaki, E, Antoniou, A, Katsoulas, T, Kounougeri, A, Marinakis, G, Tsimpoukas, F, Spyropoulou, A, Zygoulis, P, Kyparissi, A, Gupta, M, Gurjar, M, Maji, I, Hayes, I, Kelly, Y, Westbrook, A, Fitzpatrick, G, Maheshwari, D, Motherway, C, Negri, G, Spadaro, S, Nattino, G, Pedeferri, M, Boscolo, A, Rossi, S, Calicchio, G, Cubattoli, L, Di Lascio, G, Barbagallo, M, Berruto, F, Codazzi, D, Bottazzi, A, Fumagalli, P, Negro, G, Lupi, G, Savelli, F, Vulcano, G, Fumagalli, R, Marudi, A, Lefons, U, Lembo, R, Babini, M, Paggioro, A, Parrini, V, Zaccaria, M, Clementi, S, Gigliuto, C, Facondini, F, Pastorini, S, Munaron, S, Calamai, I, Bocchi, A, Adorni, A, Bocci, M, Cortegiani, A, Casalicchio, T, Mellea, S, Graziani, E, Barattini, M, Brizio, E, Rossi, M, Hahn, M, Kemmerer, N, Strietzel, H, Dybwik, K, Legernaes, T, Klepstad, P, Olaussen, E, Olsen, K, Brresen, O, Bjorsvik, G, Maini, S, Fehrle, L, Czuczwar, M, Krawczyk, P, Zietkiewicz, M, Nowak, L, Kotfis, K, Cwyl, K, Gajdosz, R, Biernawska, J, Bohatyrewicz, R, Gawda, R, Grudzien, P, Nasilowski, P, Popek, N, Cyrankiewicz, W, Wawrzyniak, K, Wnuk, M, Maciejewski, D, Studzinska, D, Zukowski, M, Bernas, S, Piechota, M, Nowak, I, Fronczek, J, Serwa, M, Machala, W, Stefaniak, J, Wujtewicz, M, Maciejewski, P, Szymkowiak, M, Adamik, B, Catorze, N, Branco, M, Barros, I, Barros, N, Krystopchuk, A, Honrado, T, Sousa, C, Munoz, F, Rebelo, M, Gomes, R, Nunes, J, Dias, C, Fernandes, A, Petrisor, C, Constantin, B, Belskiy, V, Boskholov, B, Rodriguez, E, Rebollo, S, Aguilar, G, Masdeu, G, Jaimes, M, Mira, A, Bodi, M, Barea Mendoza, J, Lopez-Cuenca, S, Guzman, M, Rico-Feijoo, J, Ibarz, M, Alvarez, J, Kawati, R, Sivik, J, Nauska, J, Smole, D, Parenmark, F, Lyren, J, Rockstroh, K, Ryden, S, Spangfors, M, Strinnholm, M, Walther, S, De Geer, L, Nordlund, P, Palsson, S, Zetterquist, H, Nilsson, A, Thiringer, K, Jungner, M, Bark, B, Nordling, B, Skold, H, Brorsson, C, Persson, S, Bergstrom, A, Berkius, J, Holmstrom, J, Abraham, P, Hergafi, L, Schefold, J, Biskup, E, van Dijk, I, van Lelyveld-Haas, L, Ramnarain, D, Jansen, T, Nooteboom, F, van der Voort, P, de Lange, D, Dieperink, W, de Waard, M, de Smet, A, Bormans, L, Dormans, T, Dempsey, G, Mathew, S, Raj, A, Grecu, I, Cupitt, J, Lawton, T, Clark, R, Popescu, M, Spittle, N, Faulkner, M, Cowton, A, Elloway, E, Williams, P, Reay, M, Chukkambotla, S, Kumar, R, Al-Subaie, N, Kent, L, Tamm, T, Kajtor, I, Burns, K, Pugh, R, Ostermann, M, Kam, E, Bowyer, H, Smith, N, Templeton, M, Henning, J, Goffin, K, Kapoor, R, Laha, S, Chilton, P, Khaliq, W, Crayford, A, Coetzee, S, Tait, M, Stoker, W, Gimenez, M, Pope, A, Camsooksai, J, Pogson, D, Quigley, K, Ritzema, J, Hormis, A, Boulanger, C, Balasubramaniam, M, Vamplew, L, Burt, K, Martin, D, Craig, J, Prowle, J, Doyle, N, Shelton, J, Scott, C, Donnison, P, Shelton, S, Frey, C, Ryan, C, Spray, D, Barnes, V, Barnes, K, Ridgway, S, Saha, R, Clark, T, Wood, J, Bolger, C, Bassford, C, Lewandowski, J, Zhao, X, Humphreys, S, Dowling, S, Richardson, N, Burtenshaw, A, Stevenson, C, Wilcock, D, Nalapko, Y, Guidet B., Flaatten H., Boumendil A., Morandi A., Andersen F.H., Artigas A., Bertolini G., Cecconi M., Christensen S., Faraldi L., Fjolner J., Jung C., Marsh B., Moreno R., Oeyen S., Ohman C.A., Pinto B.B., Soliman I.W., Szczeklik W., Valentin A., Watson X., Zafeiridis T., De Lange D.W., Schmutz R., Wimmer F., Eller P., Zotter K., De Buysscher P., De Neve N., Swinnen W., Taliadoros I., Piza P., Dey N., Solling C., Rasmussen B.S., Forceville X., Besch G., Mentec H., Michel P., Mateu P., Vettoretti L., Bourenne J., Marin N., Guillot M., Aissaoui N., Goulenok C., Thieulot-Rolin N., Messika J., Lamhaut L., Charron C., Lauten A., Sacher A.L., Brenner T., Franz M., Bloos F., Ebelt H., Schaller S.J., Fuest K., Rabe C., Dieck T., Steiner S., Graf T., Nia A.M., Janosi R.A., Simon P., Utzolino S., Rahmel T., Barth E., Schuster M., Meybohm P., Aidoni Z., Aloizos S., Tasioudis P., Lampiri K., Zisopoulou V., Ravani I., Pagaki E., Antoniou A., Katsoulas T.A., Kounougeri A., Marinakis G., Tsimpoukas F., Spyropoulou A., Zygoulis P., Kyparissi A., Gupta M., Gurjar M., Maji I.M., Hayes I., Kelly Y., Westbrook A., Fitzpatrick G., Maheshwari D., Motherway C., Negri G., Spadaro S., Nattino G., Pedeferri M., Boscolo A., Rossi S., Calicchio G., Cubattoli L., Di Lascio G., Barbagallo M., Berruto F., Codazzi D., Bottazzi A., Fumagalli P., Negro G., Lupi G., Savelli F., Vulcano G.A., Fumagalli R., Marudi A., Lefons U., Lembo R., Babini M., Paggioro A., Parrini V., Zaccaria M., Clementi S., Gigliuto C., Facondini F., Pastorini S., Munaron S., Calamai I., Bocchi A., Adorni A., Bocci M.G., Cortegiani A., Casalicchio T., Mellea S., Graziani E., Barattini M., Brizio E., Rossi M., Hahn M., Kemmerer N., Strietzel H.F., Dybwik K., Legernaes T., Klepstad P., Olaussen E.B., Olsen K.I., Brresen O.M., Bjorsvik G., Maini S., Fehrle L., Czuczwar M., Krawczyk P., Zietkiewicz M., Nowak L.R., Kotfis K., Cwyl K., Gajdosz R., Biernawska J., Bohatyrewicz R., Gawda R., Grudzien P., Nasilowski P., Popek N., Cyrankiewicz W., Wawrzyniak K., Wnuk M., Maciejewski D., Studzinska D., Zukowski M., Bernas S., Piechota M., Nowak I., Fronczek J., Serwa M., Machala W., Stefaniak J., Wujtewicz M., Maciejewski P., Szymkowiak M., Adamik B., Catorze N., Branco M.C., Barros I., Barros N., Krystopchuk A., Honrado T., Sousa C., Munoz F., Rebelo M., Gomes R., Nunes J., dias C., Fernandes A.M., Petrisor C., Constantin B., Belskiy V., Boskholov B., Rodriguez E., Rebollo S., Aguilar G., Masdeu G., Jaimes M.I., Mira A.P., Bodi M.A., Barea Mendoza J.A., Lopez-Cuenca S., Guzman M.H., Rico-Feijoo J., Ibarz M., Alvarez J.T., Kawati R., Sivik J., Nauska J., Smole D., Parenmark F., Lyren J., Rockstroh K., Ryden S., Spangfors M., Strinnholm M., Walther S., De Geer L., Nordlund P., Palsson S., Zetterquist H., Nilsson A., Thiringer K., Jungner M., Bark B., Nordling B., Skold H., Brorsson C., Persson S., Bergstrom A., Berkius J., Holmstrom J., Abraham P., Hergafi L., Schefold J.C., Biskup E., van Dijk I., van Lelyveld-Haas L.E.M., Ramnarain D., Jansen T., Nooteboom F., van der Voort P.H.J., de Lange D., Dieperink W., de Waard M.C., de Smet A.G., Bormans L., Dormans T., Dempsey G., Mathew S.J., Raj A.S., Grecu I., Cupitt J., Lawton T., Clark R., Popescu M., Spittle N., Faulkner M., Cowton A., Elloway E., Williams P., Reay M., Chukkambotla S., Kumar R., Al-Subaie N., Kent L., Tamm T., Kajtor I., Burns K., Pugh R., Ostermann M., Kam E., Bowyer H., Smith N., Templeton M., Henning J., Goffin K., Kapoor R., Laha S., Chilton P., Khaliq W., Crayford A., Coetzee S., Tait M., Stoker W., Gimenez M., Pope A., Camsooksai J., Pogson D., Quigley K., Ritzema J., Hormis A., Boulanger C., Balasubramaniam M., Vamplew L., Burt K., Martin D., Craig J., Prowle J., Doyle N., Shelton J., Scott C., Donnison P., Shelton S., Frey C., Ryan C., Spray D., Barnes V., Barnes K., Ridgway S., Saha R., Clark T., Wood J., Bolger C., Bassford C., lewandowski J., Zhao X., Humphreys S., Dowling S., Richardson N., Burtenshaw A., Stevenson C., Wilcock D., and Nalapko Y.
Subjects: End of life, ICU, withdrawing
Abstract: In the original publication Dr Patrick Meybohm of the Department of Anaesthesiology, Intensive Care Medicine and Pain Therapy, Frankfurt University Hospital, Frankfurt, Germany was inadvertently omitted from the list of investigators.
Published: 2018

31. Sex and gender differences in Alzheimer's disease: current challenges and implications for clinical practice: Position paper of the Dementia and Cognitive Disorders Panel of the European Academy of Neurology

Author: Ferretti, M T, Martinkova, J, Biskup, E, Benke, T, Gialdini, G, Nedelska, Z, Rauen, K, Mantua, V, Religa, D, Hort, J, Santuccione Chadha, A, Schmidt, R, University of Zurich, and Martinkova, J
Subjects: 2728 Neurology (clinical), 2808 Neurology, 610 Medicine & health, 11359 Institute for Regenerative Medicine (IREM)
Published: 2020

32. Thyme

Author: Stahl-Biskup, E., primary and Venskutonis, R.P., additional
Published: 2012
Full Text: View/download PDF

33. Proteasome inhibition as a novel mechanism of the proapoptotic activity of γ-secretase inhibitor I in cutaneous T-cell lymphoma

Author: Biskup, E., Kamstrup, M. R., Manfé, V., and Gniadecki, R.
Published: 2013
Full Text: View/download PDF

34. Human serum obtained from elderly individuals does not impair matrix gene expression and cell proliferation in human tendon fibroblasts: A26

Author: Bayer, M. L., Schjerling, P., Biskup, E., Herchenhan, A., Heinemeier, K. M., Doessing, S., Krogsgaard, M., and Kjaer, M.
Published: 2013

35. Notch-1 expression in cutaneous T-cell lymphomas: a potential target for therapeutic intervention: O2-6

Author: Kamstrup, MR, Gjerdrum, LMR, Biskup, E, Lauenborg, BT, Ralfkiær, E, Woetmann, A, Ødum, N, and Gniadecki, R
Published: 2012

36. Sex and gender differences in Alzheimer’s disease: current challenges and implications for clinical practice

Author: Ferretti, M. T., primary, Martinkova, J., additional, Biskup, E., additional, Benke, T., additional, Gialdini, G., additional, Nedelska, Z., additional, Rauen, K., additional, Mantua, V., additional, Religa, D., additional, Hort, J., additional, Santuccione Chadha, A., additional, and Schmidt, R., additional
Published: 2020
Full Text: View/download PDF

37. Notch signalling in primary cutaneous CD30+ lymphoproliferative disorders: a new therapeutic approach?

Author: Kamstrup, M. R., Biskup, E., and Gniadecki, R.
Published: 2010
Full Text: View/download PDF

38. Withholding or withdrawing of life-sustaining therapy in older adults (≥ 80 years) admitted to the intensive care unit

Author: Guidet B., Flaatten H., Boumendil A., Morandi A., Andersen F. H., Artigas A., Bertolini G., Cecconi M., Christensen S., Faraldi L., Fjolner J., Jung C., Marsh B., Moreno R., Oeyen S., Ohman C. A., Pinto B. B., Soliman I. W., Szczeklik W., Valentin A., Watson X., Zafeiridis T., De Lange D. W., Schmutz R., Wimmer F., Eller P., Zotter K., De Buysscher P., De Neve N., Swinnen W., Abraham P., Hergafi L., Schefold J. C., Biskup E., Taliadoros I., Piza P., Lauten A., Sacher A. L., Brenner T., Franz M., Bloos F., Ebelt H., Schaller S. J., Fuest K., Rabe C., Dieck T., Steiner S., Graf T., Nia A. M., Janosi R. A., Simon P., Utzolino S., Rahmel T., Barth E., Schuster M., Dey N., Solling C., Rasmussen B. S., Rodriguez E., Rebollo S., Aguilar G., Masdeu G., Jaimes M. I., Mira A. P., Bodi M. A., Barea Mendoza J. A., Lopez-Cuenca S., Guzman M. H., Rico-Feijoo J., Ibarz M., Alvarez J. T., Forceville X., Besch G., Mentec H., Michel P., Mateu P., Vettoretti L., Bourenne J., Marin N., Guillot M., Aissaoui N., Goulenok C., Thieulot-Rolin N., Messika J., Lamhaut L., Charron C., Dempsey G., Mathew S. J., Raj A. S., Grecu I., Cupitt J., Lawton T., Clark R., Popescu M., Spittle N., Faulkner M., Cowton A., Elloway E., Williams P., Reay M., Chukkambotla S., Kumar R., Al-Subaie N., Kent L., Tamm T., Kajtor I., Burns K., Pugh R., Ostermann M., Kam E., Bowyer H., Smith N., Templeton M., Henning J., Goffin K., Kapoor R., Laha S., Chilton P., Khaliq W., Crayford A., Coetzee S., Tait M., Stoker W., Gimenez M., Pope A., Camsooksai J., Pogson D., Quigley K., Ritzema J., Hormis A., Boulanger C., Balasubramaniam M., Vamplew L., Burt K., Martin D., Craig J., Prowle J., Doyle N., Shelton J., Scott C., Donnison P., Shelton S., Frey C., Ryan C., Spray D., Barnes V., Barnes K., Ridgway S., Saha R., Clark T., Wood J., Bolger C., Bassford C., Lewandowski J., Zhao X., Humphreys S., Dowling S., Richardson N., Burtenshaw A., Stevenson C., Wilcock D., Aidoni Z., Aloizos S., Tasioudis P., Lampiri K., Zisopoulou V., Ravani I., Pagaki E., Antoniou A., Katsoulas T. A., Kounougeri A., Marinakis G., Tsimpoukas F., Spyropoulou A., Zygoulis P., Kyparissi A., Hayes I., Kelly Y., Westbrook A., Fitzpatrick G., Maheshwari D., Motherway C., Gupta M., Gurjar M., Maji I. M., Negri G., Spadaro S., Nattino G., Pedeferri M., Boscolo A., Rossi S., Calicchio G., Cubattoli L., Di Lascio G., Barbagallo M., Berruto F., Codazzi D., Bottazzi A., Fumagalli P., Negro G., Lupi G., Savelli F., Vulcano G. A., Fumagalli R., Marudi A., Lefons U., Lembo R., Babini M., Paggioro A., Parrini V., Zaccaria M., Clementi S., Gigliuto C., Facondini F., Pastorini S., Munaron S., Calamai I., Bocchi A., Adorni A., Bocci M. G., Cortegiani A., Casalicchio T., Mellea S., Graziani E., Barattini M., Brizio E., Rossi M., van Dijk I., van Lelyveld-Haas L. E. M., Ramnarain D., Jansen T., Nooteboom F., van der Voort P. H., de Lange D., Dieperink W., de Waard M. C., de Smet A. G. E., Bormans L., Dormans T., Hahn M., Kemmerer N., Strietzel H. F., Dybwik K., Legernaes T., Klepstad P., Olaussen E. B., Olsen K. I., Brresen O. M., Bjorsvik G., Maini S., Fehrle L., Czuczwar M., Krawczyk P., Zietkiewicz M., Nowak L. R., Kotfis K., Cwyl K., Gajdosz R., Biernawska J., Bohatyrewicz R., Gawda R., Grudzien P., Nasilowski P., Popek N., Cyrankiewicz W., Wawrzyniak K., Wnuk M., Maciejewski D., Studzinska D., Zukowski M., Bernas S., Piechota M., Nowak I., Fronczek J., Serwa M., Machala W., Stefaniak J., Wujtewicz M., Maciejewski P., Szymkowiak M., Adamik B., Catorze N., Branco M. C., Barros I., Barros N., Krystopchuk A., Honrado T., Sousa C., Munoz F., Rebelo M., Gomes R., Nunes J., Dias C., Fernandes A. M., Petrisor C., Constantin B., Belskiy V., Boskholov B., Kawati R., Sivik J., Nauska J., Smole D., Parenmark F., Lyren J., Rockstroh K., Ryden S., Spangfors M., Strinnholm M., Walther S., De Geer L., Nordlund P., Palsson S., Zetterquist H., Nilsson A., Thiringer K., Jungner M., Bark B., Nordling B., Skold H., Brorsson C., Persson S., Bergstrom A., Berkius J., Holmstrom J., Nalapko Y., Service de Réanimation Médicale [CHU Saint-Antoine], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), University of Bergen (UiB), Haukeland University Hospital, Norwegian University of Science and Technology [Trondheim] (NTNU), Norwegian University of Science and Technology (NTNU), Centro de Investigación Biomédica en Red Enfermedades Respiratorias (CIBERES), Universitat Autònoma de Barcelona (UAB), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), St George's, University of London, Aarhus University Hospital, Ghent University Hospital, Karolinska University Hospital [Stockholm], Hôpitaux Universitaires de Genève (HUG), University Medical Center [Utrecht], Utrecht University [Utrecht], Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), Guidet, B, Flaatten, H, Boumendil, A, Morandi, A, Andersen, F, Artigas, A, Bertolini, G, Cecconi, M, Christensen, S, Faraldi, L, Fjolner, J, Jung, C, Marsh, B, Moreno, R, Oeyen, S, Ohman, C, Pinto, B, Soliman, I, Szczeklik, W, Valentin, A, Watson, X, Zafeiridis, T, De Lange, D, Schmutz, R, Wimmer, F, Eller, P, Zotter, K, De Buysscher, P, De Neve, N, Swinnen, W, Abraham, P, Hergafi, L, Schefold, J, Biskup, E, Taliadoros, I, Piza, P, Lauten, A, Sacher, A, Brenner, T, Franz, M, Bloos, F, Ebelt, H, Schaller, S, Fuest, K, Rabe, C, Dieck, T, Steiner, S, Graf, T, Nia, A, Janosi, R, Simon, P, Utzolino, S, Rahmel, T, Barth, E, Schuster, M, Dey, N, Solling, C, Rasmussen, B, Rodriguez, E, Rebollo, S, Aguilar, G, Masdeu, G, Jaimes, M, Mira, A, Bodi, M, Barea Mendoza, J, Lopez-Cuenca, S, Guzman, M, Rico-Feijoo, J, Ibarz, M, Alvarez, J, Forceville, X, Besch, G, Mentec, H, Michel, P, Mateu, P, Vettoretti, L, Bourenne, J, Marin, N, Guillot, M, Aissaoui, N, Goulenok, C, Thieulot-Rolin, N, Messika, J, Lamhaut, L, Charron, C, Dempsey, G, Mathew, S, Raj, A, Grecu, I, Cupitt, J, Lawton, T, Clark, R, Popescu, M, Spittle, N, Faulkner, M, Cowton, A, Elloway, E, Williams, P, Reay, M, Chukkambotla, S, Kumar, R, Al-Subaie, N, Kent, L, Tamm, T, Kajtor, I, Burns, K, Pugh, R, Ostermann, M, Kam, E, Bowyer, H, Smith, N, Templeton, M, Henning, J, Goffin, K, Kapoor, R, Laha, S, Chilton, P, Khaliq, W, Crayford, A, Coetzee, S, Tait, M, Stoker, W, Gimenez, M, Pope, A, Camsooksai, J, Pogson, D, Quigley, K, Ritzema, J, Hormis, A, Boulanger, C, Balasubramaniam, M, Vamplew, L, Burt, K, Martin, D, Craig, J, Prowle, J, Doyle, N, Shelton, J, Scott, C, Donnison, P, Shelton, S, Frey, C, Ryan, C, Spray, D, Barnes, V, Barnes, K, Ridgway, S, Saha, R, Clark, T, Wood, J, Bolger, C, Bassford, C, Lewandowski, J, Zhao, X, Humphreys, S, Dowling, S, Richardson, N, Burtenshaw, A, Stevenson, C, Wilcock, D, Aidoni, Z, Aloizos, S, Tasioudis, P, Lampiri, K, Zisopoulou, V, Ravani, I, Pagaki, E, Antoniou, A, Katsoulas, T, Kounougeri, A, Marinakis, G, Tsimpoukas, F, Spyropoulou, A, Zygoulis, P, Kyparissi, A, Hayes, I, Kelly, Y, Westbrook, A, Fitzpatrick, G, Maheshwari, D, Motherway, C, Gupta, M, Gurjar, M, Maji, I, Negri, G, Spadaro, S, Nattino, G, Pedeferri, M, Boscolo, A, Rossi, S, Calicchio, G, Cubattoli, L, Di Lascio, G, Barbagallo, M, Berruto, F, Codazzi, D, Bottazzi, A, Fumagalli, P, Negro, G, Lupi, G, Savelli, F, Vulcano, G, Fumagalli, R, Marudi, A, Lefons, U, Lembo, R, Babini, M, Paggioro, A, Parrini, V, Zaccaria, M, Clementi, S, Gigliuto, C, Facondini, F, Pastorini, S, Munaron, S, Calamai, I, Bocchi, A, Adorni, A, Bocci, M, Cortegiani, A, Casalicchio, T, Mellea, S, Graziani, E, Barattini, M, Brizio, E, Rossi, M, van Dijk, I, van Lelyveld-Haas, L, Ramnarain, D, Jansen, T, Nooteboom, F, van der Voort, P, de Lange, D, Dieperink, W, de Waard, M, de Smet, A, Bormans, L, Dormans, T, Hahn, M, Kemmerer, N, Strietzel, H, Dybwik, K, Legernaes, T, Klepstad, P, Olaussen, E, Olsen, K, Brresen, O, Bjorsvik, G, Maini, S, Fehrle, L, Czuczwar, M, Krawczyk, P, Zietkiewicz, M, Nowak, L, Kotfis, K, Cwyl, K, Gajdosz, R, Biernawska, J, Bohatyrewicz, R, Gawda, R, Grudzien, P, Nasilowski, P, Popek, N, Cyrankiewicz, W, Wawrzyniak, K, Wnuk, M, Maciejewski, D, Studzinska, D, Zukowski, M, Bernas, S, Piechota, M, Nowak, I, Fronczek, J, Serwa, M, Machala, W, Stefaniak, J, Wujtewicz, M, Maciejewski, P, Szymkowiak, M, Adamik, B, Catorze, N, Branco, M, Barros, I, Barros, N, Krystopchuk, A, Honrado, T, Sousa, C, Munoz, F, Rebelo, M, Gomes, R, Nunes, J, Dias, C, Fernandes, A, Petrisor, C, Constantin, B, Belskiy, V, Boskholov, B, Kawati, R, Sivik, J, Nauska, J, Smole, D, Parenmark, F, Lyren, J, Rockstroh, K, Ryden, S, Spangfors, M, Strinnholm, M, Walther, S, De Geer, L, Nordlund, P, Palsson, S, Zetterquist, H, Nilsson, A, Thiringer, K, Jungner, M, Bark, B, Nordling, B, Skold, H, Brorsson, C, Persson, S, Bergstrom, A, Berkius, J, Holmstrom, J, Nalapko, Y, Critical care, Anesthesiology, Peri-operative and Emergency medicine (CAPE), Guidet, Bertrand, Flaatten, Han, Boumendil, Ariane, Morandi, Alessandro, Andersen, Finn H., Artigas, Antonio, Bertolini, Guido, Cecconi, Maurizio, Christensen, Steffen, Faraldi, Loredana, Fjølner, Jesper, Jung, Christian, Marsh, Brian, Moreno, Rui, Oeyen, Sandra, Öhman, Christina Agwald, Pinto, Bernardo Bollen, Soliman, Ivo W., Szczeklik, Wojciech, Valentin, Andrea, Watson, Ximena, Zafeiridis, Tilemacho, de Lange, Dylan W., Schmutz, René, Wimmer, Franz, Eller, Philipp, Zotter, Klemen, de Buysscher, Pieter, de Neve, Nikolaa, Swinnen, Walter, Abraham, Paul, Hergafi, Leila, Schefold, Joerg C., Biskup, Ewelina, Taliadoros, Ioanni, Piza, Petr, Lauten, Alexander, Sacher, Anna Lena, Brenner, Thorsten, Franz, Marcu, Bloos, Frank, Ebelt, Henning, Schaller, Stefan J, Fuest, Kristina, Rabe, Christian, Dieck, Thorben, Steiner, Stephan, Graf, Tobia, Nia, Amir M, Janosi, Rolf Alexander, Simon, Philipp, Utzolino, Stefan, Rahmel, Tim, Barth, Eberhard, Schuster, Michael, Dey, Nilanjan, Sølling, Christoffer, Rasmussen, Bodil Steen, Rodriguez, Enver, Rebollo, Sergio, Aguilar, Gerardo, Masdeu, Gaspar, Jaimes, Marián Irazábal, Mira, Ángela Prado, Bodi, Maria A., Barea Mendoza, Jesus A., López-Cuenca, Sonia, Guzman, Marcela Homez, Rico-Feijoo, Jesú, Ibarz, Mercede, Alvarez, Josep Trenado, Forceville, Xavier, Besch, Guillaume, Mentec, Herve, Michel, Philippe, Mateu, Philippe, Vettoretti, Lucie, Bourenne, Jeremy, MARIN, Nathalie, Guillot, Max, Aissaoui, Naida, Goulenok, Cyril, Thieulot-Rolin, Nathalie, Messika, Jonathan, Lamhaut, Lionel, Charron, Cyril, Dempsey, Ged, Mathew, Shiju J, Raj, Ashok S, Grecu, Irina, Cupitt, Jason, Lawton, Tom, Clark, Richard, Popescu, Monica, Spittle, Nick, Faulkner, Maria, Cowton, Amanda, Elloway, Esme, Williams, Patricia, Reay, Michael, Chukkambotla, Srikanth, Kumar, Ravi, Al-Subaie, Nawaf, Kent, Linda, Tamm, Tiina, Kajtor, Istvan, Burns, Karen, Pugh, Richard, Ostermann, Marlie, Kam, Elisa, Bowyer, Helen, Smith, Neil, Templeton, Maie, Henning, Jeremy, Goffin, Kelly, Kapoor, Ritoo, Laha, Shondipon, Chilton, Phil, Khaliq, Waqa, Crayford, Alison, Coetzee, Samantha, Tait, Moira, Stoker, Wendy, Gimenez, Marc, Pope, Alan, Camsooksai, Julie, Pogson, David, Quigley, Kate, Ritzema, Jenny, Hormis, Anil, Boulanger, Carole, Balasubramaniam, M., Vamplew, Luke, Burt, Karen, Martin, Daniel, Craig, Jayne, Prowle, John, Doyle, Nanci, Shelton, Jonathon, Scott, Carmen, Donnison, Phil, Shelton, Sarah, Frey, Christian, Ryan, Christine, Spray, Dominic, Barnes, Veronica, Barnes, Kerry, Ridgway, Stephanie, Saha, Rajnish, Clark, Thoma, Wood, Jame, Bolger, Clare, Bassford, Christopher, Lewandowski, John, Zhao, Xiaobei, Humphreys, Sally, Dowling, Susan, Richardson, Neil, Burtenshaw, Andrew, Stevenson, Carl, Wilcock, Danielle, Aidoni, Zoi, Aloizos, Stavro, Tasioudis, Polychroni, Lampiri, Kleri, Zisopoulou, Vasiliki, Ravani, Ifigenia, Pagaki, Eumorfia, Antoniou, Angela, Katsoulas, Theodoros A., Kounougeri, Aikaterini, Marinakis, George, Tsimpoukas, Fotio, Spyropoulou, Anastasia, Zygoulis, Pari, Kyparissi, Aikaterini, Hayes, Ivan, Kelly, Yvelynne, Westbrook, Andrew, Fitzpatrick, Gerry, Maheshwari, Darshana, Motherway, Catherine, Gupta, Manish, Gurjar, Mohan, Maji, Ismail M, Negri, Giovanni, Spadaro, Savino, Nattino, Giuseppe, Pedeferri, Matteo, Boscolo, Annalisa, Rossi, Simona, Calicchio, Giuseppe, Cubattoli, Lucia, Di Lascio, Gabriella, Barbagallo, Maria, Berruto, Francesco, Codazzi, Daniela, Bottazzi, Andrea, Fumagalli, Paolo, Negro, Giancarlo, Lupi, Giuseppe, Savelli, Flavia, Vulcano, Giuseppe A., Fumagalli, Roberto, Marudi, Andrea, Lefons, Ugo, Lembo, Rita, Babini, Maria, Paggioro, Alessandra, Parrini, Vieri, Zaccaria, Maria, Clementi, Stefano, Gigliuto, Carmelo, Facondini, Francesca, Pastorini, Simonetta, Munaron, Susanna, Calamai, Italo, Bocchi, Anna, Adorni, Adele, Bocci, Maria Grazia, Cortegiani, Andrea, Casalicchio, Tiziana, Mellea, Serena, Graziani, Elia, Barattini, Massimo, Brizio, Elisabetta, Rossi, Maurizio, van Dijk, I., van Lelyveld-Haas, L.E.M., Ramnarain, D., Jansen, Tim, Nooteboom, Fleur, van der Voort, Peter HJ, de Lange, Dylan, Dieperink, Willem, de Waard, Monique C., de Smet, Annemarie G. E., Bormans, Laura, Dormans, Tom, Hahn, Michael, Kemmerer, Nicolai, Strietzel, Hans Frank, Dybwik, Knut, Legernaes, Terje, Klepstad, Pål, Olaussen, Even Braut, Olsen, Knut Inge, Brresen, Ole Mariu, Bjorsvik, Geir, Maini, Sameer, Fehrle, Lutz, Czuczwar, Miroslaw, Krawczyk, Pawel, Ziętkiewicz, Mirosław, Nowak, Łukasz R., Kotfis, Katarzyna, Cwyl, Katarzyna, Gajdosz, Ryszard, Biernawska, Jowita, Bohatyrewicz, Romuald, Gawda, Ryszard, Grudzień, Paweł, Nasiłowski, Paweł, Popek, Natalia, Cyrankiewicz, Waldemar, Wawrzyniak, Katarzyna, Wnuk, Marek, Maciejewski, Dariusz, Studzińska, Dorota, Żukowski, Maciej, Bernas, Szymon, Piechota, Mariusz, Nowak, Ilona, Fronczek, Jakub, Serwa, Marta, Machała, Waldemar, Stefaniak, Jan, Wujtewicz, Maria, Maciejewski, Paweł, Szymkowiak, Małgorzata, Adamik, Barbara, Catorze, Nuno, Branco, Miguel Castelo, Barros, Inê, Barros, Nelson, Krystopchuk, Andriy, Honrado, Teresa, Sousa, Cristina, Munoz, Francisco, Rebelo, Marta, Gomes, Rui, Nunes, Jorge, Dias, Celeste, Fernandes, Ana Margarida, Petrisor, Cristina, Constantin, Bodolea, Belskiy, Vladislav, Boskholov, Bori, Kawati, Rafael, Sivik, Joakim, Nauska, Jessica, Smole, Daniel, Parenmark, Fredric, Lyrén, Johanna, Rockstroh, Katalin, Rydén, Sara, Spångfors, Martin, Strinnholm, Morten, Walther, Sten, de Geer, Lina, Nordlund, Peter, Pålsson, Staffan, Zetterquist, Harald, Nilsson, Annika, Thiringer, Karin, Jungner, Mårten, Bark, Björn, Nordling, Berit, Sköld, Han, Brorsson, Camilla, Persson, Stefan, Bergström, Anna, Berkius, Johan, Holmström, Johanna, Nalapko, Yuiry, and Critical Care
Subjects: Male, medicine.medical_treatment, HSJ UCI, Critical Care and Intensive Care Medicine, law.invention, Life sustaining treatment, 0302 clinical medicine, Elderly, law, 80 and over, Medicine, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, Aged, 80 and over, education.field_of_study, Withholding Treatment, ddc:617, [SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontology, Withholding, Intensive care unit, 3. Good health, Europe, aged, Intensive Care Units, Withdrawal, SOFA score, Human, medicine.medical_specialty, ethical aspects, Population, Intensive Care Unit, Decision Making, Ethics, Intensive care, life-sustaining therapy, NO, 03 medical and health sciences, Anesthesiology, Humans, Ethic, education, Mechanical ventilation, business.industry, 030208 emergency & critical care medicine, critical care, Life Support Care, Prospective Studie, Emergency medicine, business
Abstract: PURPOSE: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU. METHODS: This prospective study included intensive care patients aged ≥ 80 years in 309 ICUs from 21 European countries with 30-day mortality follow-up. RESULTS: LST limitation was identified in 1356/5021 (27.2%) of patients: 15% had a withholding decision and 12.2% a withdrawal decision (including those with a previous withholding decision). Patients with LST limitation were older, more frail, more severely ill and less frequently electively admitted. Patients with withdrawal of LST were more frequently male and had a longer ICU length of stay. The ICU and 30-day mortality were, respectively, 29.1 and 53.1% in the withholding group and 82.2% and 93.1% in the withdrawal group. LST was less frequently limited in eastern and southern European countries than in northern Europe. The patient-independent factors associated with LST limitation were: acute ICU admission (OR 5.77, 95% CI 4.32-7.7), Clinical Frailty Scale (CFS) score (OR 2.08, 95% CI 1.78-2.42), increased age (each 5 years of increase in age had a OR of 1.22 (95% CI 1.12-1.34) and SOFA score [OR of 1.07 (95% CI 1.05-1.09 per point)]. The frequency of LST limitation was higher in countries with high GDP and was lower in religious countries. CONCLUSIONS: The most important patient variables associated with the instigation of LST limitation were acute admission, frailty, age, admission SOFA score and country. TRIAL REGISTRATION: ClinicalTrials.gov (ID: NTC03134807). info:eu-repo/semantics/publishedVersion
Published: 2018

39. Thyme

Author: Venskutonis, R, primary and Stahl-Biskup, E, additional
Published: 2004
Full Text: View/download PDF

40. Thyme

Author: Stahl-Biskup, E., primary and Venskutonis, R.P., additional
Published: 2004
Full Text: View/download PDF

41. Contributors

Author: Peter, K.V., primary, Nirmal Babu, K., additional, Shylaja, M.R., additional, Peter, K.V., additional, Tassou, C.C., additional, Nychas, G.-J.E., additional, Skandamis, P.N., additional, Rodenburg, R., additional, Ravindran, P.N., additional, Pillai, G.S., additional, Malhotra, S.K., additional, Vijay, O.P., additional, Krishnamoorthy, B., additional, Rema, J., additional, Farooqi, A.A., additional, Srinivasappa, K.N., additional, Sharma, M.M., additional, Sharma, R.K., additional, Lis-Balchin, M.T., additional, Thomas, J., additional, Kuruvilla, K.M., additional, Hrideek, T.K., additional, Kintzios, S., additional, Charles, D.J., additional, Sasikumar, B., additional, Hegde, D.M., additional, George, C.K., additional, Stahl-Biskup, E., additional, Venskutonis, R.P., additional, and de Guzman, C.C., additional
Published: 2004
Full Text: View/download PDF

42. Women, partners, and mothers-migratory tendencies of psychiatric trainees across europe

Author: da Costa, M.P. Giurgiuca, A. Andreou, E. Baessler, F. Banjac, V. Biskup, E. Dragasek, J. El-Higaya, E. Feffer, K. Frydecka, D. Kaaja, J. Kanellopoulos, A. Kilic, O. Marinova, P. Mitkovic-Voncina, M. Molina-Ruiz, R. Palumbo, C. Pantovic-Stefanovic, M. Rakos, I. Stoyanova, M. Tomori, S. De Picker, L.D.
Abstract: Introduction: Combining a successful career with family planning has become increasingly important in recent years. However, maintaining a relationship, deciding upon the optimal time for pregnancy and other family planning decisions can still be quite challenging, especially for junior doctors whose training is long and demanding. Currently, women form an important part of the medical workforce, and there is noticeable feminization in migration. However, little is known about the personal characteristics of junior doctors in Europe and how these play a role in their decision to migrate. Methods: Survey of psychiatric trainees in 33 European countries, exploring how personal characteristics, such as gender, relationship status and parenthood, impact their attitudes toward migration. Results: 2,281 psychiatric trainees in Europe took part in the study. In this sample, the majority of psychiatric trainees were in a relationship, but only one quarter had children, although there were variations across Europe. Both men and women indicated personal reasons as their top reason to stay. However, women ranked personal reasons as the top reason to leave, and men financial reasons. Single woman were the most likely of all subgroups to choose academic reasons as their top reason to leave. Interestingly, when women were in a relationship or had children, their attitudes toward migration changed. Conclusions: In this study, a low number of psychiatric trainees in Europe had children, with differences across Europe. These findings raise awareness as to the role of parental conditions, which may be favoring or discouraging parenthood in junior doctors in different countries. © 2019 Pinto da Costa, Giurgiuca, Andreou, Baessler, Banjac, Biskup, Dragasek, El-Higaya, Feffer, Frydecka, Kaaja, Kanellopoulos, Kilic, Marinova, Mitkovic-Voncina, Molina-Ruiz, Palumbo, Pantovic-Stefanovic, Rakos, Stoyanova, Tomori and De Picker.
Published: 2019

43. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: 'AbSeS', a multinational observational cohort study and ESICM Trials Group Project

Author: Blot, S. Antonelli, M. Arvaniti, K. Blot, K. Creagh-Brown, B. de Lange, D. De Waele, J. Deschepper, M. Dikmen, Y. Dimopoulos, G. Eckmann, C. Francois, G. Girardis, M. Koulenti, D. Labeau, S. Lipman, J. Lipovestky, F. Maseda, E. Montravers, P. Mikstacki, A. Paiva, J.-A. Pereyra, C. Rello, J. Timsit, J.-F. Vogelaers, D. Lamrous, A. Rezende-Neto, J. Cardenas, Y. Vymazal, T. Fjeldsoee-Nielsen, H. Kott, M. Kostoula, A. Javeri, Y. Einav, S. Makikado, L.D.U. Tomescu, D. Gritsan, A. Jovanovic, B. Venkatesan, K. Mirkovic, T. Creagh-Brown, B. Lamrous, A. Emmerich, M. Canale, M. Dietz, L.S. Ilutovich, S. Miñope, J.T.S. Silva, R.B. Montenegro, M.A. Martin, P. Saul, P. Chediack, V. Sutton, G. Couce, R. Balasini, C. Gonzalez, S. Lascar, F.M. Descotte, E.J. Gumiela, N.S. Pino, C.A. Cesio, C. Valgolio, E. Cunto, E. Dominguez, C. Nelson, N.F. Abegao, E.M. Pozo, N.C. Bianchi, L. Correger, E. Pastorino, M.L. Miyazaki, E.A. Pozo, N.C. Grubissich, N. Garcia, M. Bonetto, N. Quevedo, N.E. Gomez, C.D. Queti, F. Estevarena, L.G. Fernandez, R. Santolaya, I. Pozo, N.C. Grangeat, S.H. Doglia, J. Zakalik, G. Pellegrini, C. Lloria, M.M. Chacon, M.E. Fumale, M. Leguizamon, M. Hidalgo, I.B. Tiranti, R.J. Capponi, P. Tita, A. Cardonnet, L. Bettini, L. Ramos, A. Lovesio, L. Miranda, E.M. Farfan, A.B. Tolosa, C. Segura, L. Bellocchio, A. Alvarez, B. Manzur, A. Lujan, R. Fernandez, N. Scarone, N. Zazu, A. Groh, C. Fletcher, J. Smith, J. Azad, R. Chavan, N. Wong, H. Kol, M. Campbell, L. Starr, T. Roberts, B. Wibrow, B. Warhurst, T. Chinthamuneedi, M. Ferney, B.B. Simon, M. De Backer, D. Wittebole, X. De Bels, D. Collin, V. Dams, K. Jorens, P. Dubois, J. Gunst, J. Haentjens, L. De Schryver, N. Dugernier, T. Rezende-Neto, J. Rizoli, S. Santillan, P. Han, Y. Biskup, E. Qu, C. Li, X. Yu, T. Weihua, L. Molano-Franco, D. Rojas, J. Oviedo, J.M.P. Pinilla, D. Cardenas, Y. Celis, E. Arias, M. Vukovic, A. Vudrag, M. Belavic, M. Zunic, J. Kuharic, J. Kricka, I.B. Filipovic-Grcic, I. Tomasevic, B. Obraz, M. Bodulica, B. Dohnal, M. Malaska, J. Kratochvil, M. Satinsky, I. Schwarz, P. Kos, Z. Blahut, L. Maca, J. Protus, M. Kieslichová, E. Nielsen, L.G. Krogh, B.M. Rivadeneira, F. Morales, F. Mora, J. Orozco, A.S. MorochoTutillo, D.R. Vargas, N.R. Yepez, E.S. Villamagua, B. Alsisi, A. Fahmy, A. Dupont, H. Lasocki, S. Paugam-Burtz, C. Foucrier, A. Nica, A. Barjon, G. Mallat, J. Marcotte, G. Leone, M. Duclos, G. Burtin, P. Atchade, E. Mahjoub, Y. Misset, B. Timsit, J.-F. Dupuis, C. Veber, B. Debarre, M. Collange, O. Pottecher, J. Hecketsweiler, S. Fromentin, M. Tesnière, A. Koch, C. Sander, M. Kott, M. Elke, G. Wrigge, H. Simon, P. Chalkiadaki, A. Tzanidakis, C. Pneumatikos, I. Sertaridou, E. Mastora, Z. Pantazopoulos, I. Papanikolaou, M. Papavasilopoulou, T. Floros, J. Kolonia, V. Diakaki, C. Rallis, M. Paridou, A. Kalogeromitros, A. Romanou, V. Nikolaou, C. Kounougeri, K. Tsigou, E. Psallida, V. Karampela, N. Mandragos, K. Kontoudaki, E. Pentheroudaki, A. Farazi-Chongouki, C. Karakosta, A. Chouris, I. Radu, V. Malliotakis, P. Kokkini, S. Charalambous, E. Kyritsi, A. Koulouras, V. Papathanakos, G. Nagky, E. Lampiri, C. Tsimpoukas, F. Sarakatsanos, I. Georgakopoulos, P. Ravani, I. Prekates, A. Sakellaridis, K. Christopoulos, C. Vrettou, E. Stokkos, K. Pentari, A. Marmanidou, K. Kydona, C. Tsoumaropoulos, G. Bitzani, M. Kontou, P. Voudouris, A. Elli-Nikki Flioni Antypa, E. Chasou, E. Anisoglou, S. Papageorgiou, E. Paraforou, T. Tsioka, A. Karathanou, A. Vakalos, A. Shah, B. Thakkar, C. Jain, N. Gurjar, M. Baronia, A. Sathe, P. Kulkarni, S. Paul, C. Paul, J. Masjedi, M. Nikandish, R. Zand, F. Sabetian, G. Mahmoodpoor, A. Hashemian, S.M. Bala, M. Flocco, R. Torrente, S. Pota, V. Spadaro, S. Volta, C. Serafini, G. Boraso, S. Tiberio, I. Cortegiani, A. Misseri, G. Barbagallo, M. Nicolotti, D. Forfori, F. Corradi, F. De Pascale, G. Pelagalli, L. Brazzi, L. Vittone, F.G. Russo, A. Simion, D. Cotoia, A. Cinnella, G. Toppin, P. Johnson-Jackson, R. Hayashi, Y. Yamamoto, R. Yasuda, H. Kishihara, Y. Shiotsuka, J. Sanchez-Hurtado, L.A. Tejeda-Huezo, B. Gorordo, L. Ñamendys-Silva, S.A. Garcia-Guillen, F.J. Martinez, M. Romero-Meja, E. Colorado-Dominguez, E. van den Oever, H. Kalff, K.M. Vermeijden, W. Cornet, A.D. Beck, O. Cimic, N. Dormans, T. Bormans, L. Bakker, J. Van Duijn, D. Bosman, G. Vos, P. Haas, L. Henein, A. Miranda, A.M. Makikado, L.D.U. Malca, G.E.G. Arroyo-Sanchez, A. Misiewska-Kaczur, A. Akinyi, F. Czuczwar, M. Luczak, K. Sulkowski, W. Tamowicz, B. Swit, B. Baranowski, B. Smuszkiewicz, P. Trojanowska, I. Rzymski, S. Sawinski, M. Trosiak, M. Mikaszewska-Sokolewicz, M. Alves, R. Leal, D. Krystopchuk, A. Mendonca, P.M.H. Pereira, R.A. de Carvalho, M.R.L.M. Candeias, C. Molinos, E. Ferreira, A. Castro, G. Pereira, J.-M. Santos, L. Ferreira, A. Pascoalinho, D. Ribeiro, R. Domingos, G. Gomes, P. Nora, D. Costa, R.P. Santos, A. Alsheikhly, A.S. Tomescu, D. Popescu, M. Grigoras, I. Patrascanu, E. Zabolotskikh, I. Musaeva, T. Gaigolnik, D. Kulabukhov, V. Belskiy, V. Zubareva, N. Tribulev, M. Abdelsalam, A. Aldarsani, A. Al-Khalid, M. Almekhlafi, G. Mandourah, Y. Jovanovic, B. Doklestic, K. Velickovic, J. Velickovic, D. Jankovic, R. Vukovic, A. Skoric-Jokic, S. Radovanovic, D. Richards, G. Alli, A. del Carmen Cordoba Nielfa, M. Iniesta, R.S. Martínez, A.B.-C. Bernedo, C.G. Gil, S.A.P. Nuvials, X. Garcia, J.G. Peña, J.M.G. Jimenez, R. Herrera, L. Barrachina, L.G. Monzon, I.C. Redondo, F.J. Villazala, R. Zapata, D.F.M. Lopez, I.M.V. Moreno-Gonzalez, G. Lopez-Delgado, J.C. Marin, J.S. Sanchez-Zamora, P. Vidal, M.V. González, J.F. Salinas, I. Hermosa, C. Martinez-Sagasti, F. Domingo-Marín, S. Victorino, J.A. Garcia-Alvarez, R. Calleja, P.L.-A. de la Torre-Prados, M.-V. Vidal-Cortes, P. del Río-Carbajo, L. Izura, J. Minguez, V. Alvarez, J.T. Prous, A.P. Paz, D. Roche-Campo, F. Aguilar, G. Belda, J. Rico-Feijoo, J. Aldecoa, C. Zalba-Etayo, B. Lang, M. Dullenkopf, A. Trongtrakul, K. Chtsomkasem, A. Akbas, T. Unal, M.N. Ozcelik, M. Gumus, A. Ramazanoglu, A. Memis, D. Mehmet, I. Urkmez, S. Ozgultekin, A. Demirkiran, O. Aslan, N.A. Kizilaslan, D. Kahveci, F. Ünlü, N. Ozkan, Z. Kaye, C. Jansen, J. O’Neill, O. Nutt, C. Jha, R. Hooker, N. Grecu, I. Petridou, C. Shyamsundar, M. McNamee, L. Trinder, J. Hagan, S. Kelly, C. Silversides, J. Groba, C.B. Boyd, O. Bhowmick, K. Humphreys, S. Summers, C. Polgarova, P. Margarson, M. Dickens, J. Pearson, S. Chinery, E. Hemmings, N. O’Kane, S. Austin, P. Cole, S. Plowright, C. Box, R. Wright, C. Young, L. Montague, L. Parker, R. Morton, B. Ostermann, M. Bilinska, J. Rose, B.O. Reece-Anthony, R. Ryan, C. Hamilton, M. Hopkins, P. Wendon, J. Brescia, G. Ijaz, N. Wood, J. George, M. Toth-Tarsoly, P. Yates, B. Armstrong, M. Scott, C. Boyd, C. Szakmany, T. Rees, D. Pulak, P. Coggon, M. Saha, B. Kent, L. Gibson, B. Camsooksai, J. Reschreiter, H. Morgan, P. Sangaralingham, S. Lowe, A. Vondras, P. Jamadarkhana, S. Cruz, C. Bhandary, R. Hersey, P. Furneval, J. Innes, R. Doble, P. Attwood, B. Parsons, P. Page, V. Zhao, X. Grecu, I. Dalton, J. Hegazy, M. Awad, Y. Naylor, D. Naylor, A. Lee, S. Brevard, S. Davis, N. the Abdominal Sepsis Study (AbSeS) group on behalf of the Trials Group of the European Society of Intensive Care Medicine
Abstract: Purpose: To describe the epidemiology of intra-abdominal infection in an international cohort of ICU patients according to a new system that classifies cases according to setting of infection acquisition (community-acquired, early onset hospital-acquired, and late-onset hospital-acquired), anatomical disruption (absent or present with localized or diffuse peritonitis), and severity of disease expression (infection, sepsis, and septic shock). Methods: We performed a multicenter (n = 309), observational, epidemiological study including adult ICU patients diagnosed with intra-abdominal infection. Risk factors for mortality were assessed by logistic regression analysis. Results: The cohort included 2621 patients. Setting of infection acquisition was community-acquired in 31.6%, early onset hospital-acquired in 25%, and late-onset hospital-acquired in 43.4% of patients. Overall prevalence of antimicrobial resistance was 26.3% and difficult-to-treat resistant Gram-negative bacteria 4.3%, with great variation according to geographic region. No difference in prevalence of antimicrobial resistance was observed according to setting of infection acquisition. Overall mortality was 29.1%. Independent risk factors for mortality included late-onset hospital-acquired infection, diffuse peritonitis, sepsis, septic shock, older age, malnutrition, liver failure, congestive heart failure, antimicrobial resistance (either methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, extended-spectrum beta-lactamase-producing Gram-negative bacteria, or carbapenem-resistant Gram-negative bacteria) and source control failure evidenced by either the need for surgical revision or persistent inflammation. Conclusion: This multinational, heterogeneous cohort of ICU patients with intra-abdominal infection revealed that setting of infection acquisition, anatomical disruption, and severity of disease expression are disease-specific phenotypic characteristics associated with outcome, irrespective of the type of infection. Antimicrobial resistance is equally common in community-acquired as in hospital-acquired infection. © 2019, The Author(s).
Published: 2019

44. p-CREB-1 at Ser 133 is a potential marker for breast cancer.

Author: XIN, Z.-C., HU, H.-W., LAO, Z.-H., ZHU, L.-Q., BISKUP, E., and ZHANG, H.-W.
Abstract: OBJECTIVE: Dysregulation of numerous oncogenes and their downstream signaling pathways, among others in the signaling transduction molecule p-CREB-1 (p-cAMP responsive element binding protein-1), is an essential feature of different types of cancer. To investigate whether p-CREB-1 is also pivotal in tumorigenesis and metastogenesis of breast cancer, we conducted a prospective study with longterm follow-up on 96 patients with breast cancer. PATIENTS AND METHODS: Pathway array and tissue microarray (TMA) were used to detect the differential expression of CREB (cAMP-responsive element binding protein) and p-CREB-1 in breast cancer cells, breast cancer stem cells (BCSCs), human breast cancer tissues (BCTs), and adjacent normal tissues (ANTs). The associations between p-CREB-1 expression, clinicopathological variables, and survival rates of the patients were analyzed and calculated. RESULTS: Our results revealed that p-CREB-1 and CREB expression in cancerous cell lines and tissues were significantly upregulated compared with non-cancerous cell lines and tissues. Most statistically significant overexpression was detected in BCSCs (p<0.01). In TMA and immunohistochemical analyses, BCTs exhibited significantly higher expression of p-CREB-1 and CREB than ANTs (p<0.001). Clinicopathological variable and survival analysis revealed a correlation between high expression (++/+++) of p-CREB-1 and the presence of axillary lymph node metastasis (p<0.05) and poorer disease-free and overall survival. CONCLUSIONS: p-CREB-1 is a potential predictive and prognostic biomarker and a promising therapeutic target in breast cancer. [ABSTRACT FROM AUTHOR]
Published: 2020

45. USP2 as a potential link between miR-125b and psoriasis

Author: Wei, T., Folkersen, Lasse Westergaard, Biskup, E., Xu, N., Manfe, V., Niazi, O., and Gniadecki, R.
Abstract: BackgroundThe extensive involvement of microRNA (miRNA) in the pathophysiology of psoriasis is well documented. However, in order for this information to be useful in therapeutic manipulation of miRNA levels, it is essential that detailed functional mechanisms are elucidated. miR-125b has previously been shown to be strongly associated with psoriasis, and presents as an obvious candidate for further investigation.ObjectivesTo elucidate the specific pathway and mechanism of interest in this association.MethodsA three-step bioinformatical hypothesis-generation pipeline was performed to identify genes of interest. This pipeline was based on miR-125b binding, expression in psoriatic lesions and genome-wide association study-based evidence of involvement. The identified candidate gene was then carefully evaluated using luciferase binding assays, in vitro overexpression, small interfering RNA knock-down and downstream gene readouts.ResultsBased on our bioinformatical pipeline, ubiquitin-specific peptidase 2 was selected as a likely candidate for a mechanistic explanation for psoriasis association. After establishing a definite connection to miR-125b, we proceeded to show that modulation of nuclear factor kappa B-mediated inflammation is the likely mechanism through which this miRNA gene pair functioned.ConclusionsShedding further light on the multifactorial causes of psoriasis is essential, if the goal is to progress towards finer control of therapeutic tools in disease management. Findings, such as the ones presented herein, are therefore necessary in order to achieve the future of personalized medicine.
Published: 2017

46. To which countries do European psychiatric trainees want to move to and why?

Author: Pinto da Costa, M. Giurgiuca, A. Holmes, K. Biskup, E. Mogren, T. Tomori, S. Kilic, O. Banjac, V. Molina-Ruiz, R. Palumbo, C. Frydecka, D. Kaaja, J. El-Higaya, E. Kanellopoulos, A. Amit, B.H. Madissoon, D. Andreou, E. Uleviciute-Belena, I. Rakos, I. Dragasek, J. Feffer, K. Farrugia, M. Mitkovic-Voncina, M. Gargot, T. Baessler, F. Pantovic-Stefanovic, M. De Picker, L.
Abstract: Background There is a shortage of psychiatrists worldwide. Within Europe, psychiatric trainees can move between countries, which increases the problem in some countries and alleviates it in others. However, little is known about the reasons psychiatric trainees move to another country. Methods Survey of psychiatric trainees in 33 European countries, exploring how frequently psychiatric trainees have migrated or want to migrate, their reasons to stay and leave the country, and the countries where they come from and where they move to. A 61-item self-report questionnaire was developed, covering questions about their demographics, experiences of short-term mobility (from 3 months up to 1 year), experiences of long-term migration (of more than 1 year) and their attitudes towards migration. Results A total of 2281 psychiatric trainees in Europe participated in the survey, of which 72.0% have ‘ever’ considered to move to a different country in their future, 53.5% were considering it ‘now’, at the time of the survey, and 13.3% had already moved country. For these immigrant trainees, academic was the main reason they gave to move from their country of origin. For all trainees, the overall main reason for which they would leave was financial (34.4%), especially in those with lower (2500€) incomes, personal reasons were paramount (44.5%). Conclusions A high number of psychiatric trainees considered moving to another country, and their motivation largely reflects the substantial salary differences. These findings suggest tackling financial conditions and academic opportunities. © 2017 Elsevier Masson SAS
Published: 2017

47. PO-044 Possible involvement of G2/M block defects in cell sensitivity towards ATR inhibitors

Author: Biskup, E., primary, Niazi, O., additional, Pless, V., additional, and Gniadecki, R., additional
Published: 2018
Full Text: View/download PDF

48. To which countries do European psychiatric trainees want to move to and why?

Author: Pinto da Costa, M., primary, Giurgiuca, A., additional, Holmes, K., additional, Biskup, E., additional, Mogren, T., additional, Tomori, S., additional, Kilic, O., additional, Banjac, V., additional, Molina-Ruiz, R., additional, Palumbo, C., additional, Frydecka, D., additional, Kaaja, J., additional, El-Higaya, E., additional, Kanellopoulos, A., additional, Amit, B.H., additional, Madissoon, D., additional, Andreou, E., additional, Uleviciute-Belena, I., additional, Rakos, I., additional, Dragasek, J., additional, Feffer, K., additional, Farrugia, M., additional, Mitkovic-Voncina, M., additional, Gargot, T., additional, Baessler, F., additional, Pantovic-Stefanovic, M., additional, and De Picker, L., additional
Published: 2017
Full Text: View/download PDF

49. The EFPT-PSUD survey

Author: Rojnic Palavra, I., primary, Orsolini, L., additional, Potocan, M., additional, Diego, Q., additional, Martens, M., additional, Levola, J., additional, Grichy, L., additional, Gondek, T.M., additional, Dias, M. Casanova, additional, Pinto da Costa, M., additional, Tomori, S., additional, Mullerova, S., additional, Sonmez, E., additional, Borovcanin, M., additional, Banjac, V., additional, Marinova, P., additional, Pakutkaitė, I.K., additional, Kuiters, J., additional, Popescu, A.L., additional, Biskup, E., additional, Naughton, S., additional, and San Roman Uria, A., additional
Published: 2017
Full Text: View/download PDF

50. Native vs. Migrants – same Opportunities or Discriminated? – Psychiatry Trainees's Views from the EFPT Brain Drain Study

Author: Costa, M. Pinto da, primary, Tomori, S., additional, Mogren, T., additional, Biskup, E., additional, Baessler, F., additional, Frydecka, D., additional, Killic, O., additional, and Group, E. Research, additional
Published: 2017
Full Text: View/download PDF

Catalog

Books, media, physical & digital resources

See catalog results

Searchworks

Select search scope, currently: Articles Catalog books, media & more in Jio Institute collections Articles journal articles & other e-resources

Search

Search Constraints

Refine your results

Search Limiters

Topic

Publication Year Range

Language

Publication Type

Journal

Region

Database

Publisher

260 results on '"Biskup E"'

Search Results

Catalog

Select search scope, currently: Articles

Catalog

books, media & more in Jio Institute collections

Articles

journal articles & other e-resources