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9. Abstract WP1: Analyzing Door-to-Needle Time Trends: Tenecteplase vs. Alteplase in Acute Ischemic Stroke Treatment

Author

Rodriguez, Nathaniel, primary, Prasad, Sidarrth, additional, Gealogo Brown, Gretchel, additional, Bandela, Sujani, additional, Stone, Suzanne, additional, Olson, Daiwai M, additional, Anderson, Jane A, additional, Savitz, Sean I, additional, Flores, Salvador Cruz, additional, Warach, Steven J, additional, Rhodes, Charlotte, additional, Goldberg, Mark P, additional, and Birnbaum, Lee, additional

Published
2024
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11. Technical and clinical success after venous sinus stenting for treatment of idiopathic intracranial hypertension using a novel guide catheter for access: Case series and initial multi-center experience.

Author

Zyck, Stephanie, Malik, Muhammad, Webb, Matthew, Mohammed, Marwa, Powers, Ciaran J, Birnbaum, Lee, Hawk, Harris, Brinjikji, Waleed, and Nimjee, Shahid M.

Subjects
CEREBROSPINAL fluid shunts, CATHETERIZATION, DATABASES, WOMEN patients, CATHETERS
Abstract

Introduction: Venous sinus stenting is a well established alternative to cerebrospinal fluid diversion for the treatment of idiopathic intracranial hypertension (IIH) with associated venous sinus stenosis. During this procedure, distal guide catheter placement within the venous sinuses may be desirable to facilitate stent delivery. We report our initial experience using the TracStar LDP™ (Imperative Care, Campbell, USA, 0.088-inch inner diameter) as the guide catheter for intracranial access during venous sinus stenting. Methods: A multi-institutional retrospective chart review of a prospectively maintained IRB-approved database was performed. Consecutive patients who underwent venous sinus stenting from 1/1/2020-9/6/2021 for IIH were included. Patient characteristics, procedural details, TracStar distal reach, outcomes, and complications were collected and analyzed. Results: Fifty-eight patients were included. The mean age was 33.8 years and 93.1% of patients were female. Visual changes prompted evaluation in 86.2% of patients. Stent placement was successful in all patients. The TracStar LDP catheter was advanced to the location of stent placement in 97.9% of cases in which it was attempted. The large 0.088-inch inner diameter lumen enabled compatibility with all desired stent sizes ranging from six to 10 millimeters. Gradient pressure across transverse sinus stenosis dropped from an average of 19.5 mmHg pre-procedure to 1.7 mmHg post-stent placement (p < 0.001). Clinical improvement was achieved in 87.9% (51/58) of patients. There were no catheter-related complications. Conclusion: The TracStar LDP is a safe and effective access platform for reaching treatment locations in patients who present with idiopathic intracranial hypertension and who are candidates for venous sinus stent placement. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Flow Diversion for Endovascular Treatment of Intracranial Aneurysms: Past, Present, and Future Directions.

Author

Gaub, Michael, Murtha, Greg, Lafuente, Molly, Webb, Matthew, Luo, Anqi, Birnbaum, Lee A., Mascitelli, Justin R., and Al Saiegh, Fadi

Subjects
INTRACRANIAL aneurysms, RUPTURED aneurysms, INTRACRANIAL aneurysm ruptures, ENDOVASCULAR surgery, ARTIFICIAL intelligence
Abstract

Flow diversion for intracranial aneurysms emerged as an efficacious and durable treatment option over the last two decades. In a paradigm shift from intrasaccular aneurysm embolization to parent vessel remodeling as the mechanism of action, the proliferation of flow-diverting devices has enabled the treatment of many aneurysms previously considered untreatable. In this review, we review the history and development of flow diverters, highlight the pivotal clinical trials leading to their regulatory approval, review current devices including endoluminal and intrasaccular flow diverters, and discuss current and expanding indications for their use. Areas of clinical equipoise, including ruptured aneurysms and wide-neck bifurcation aneurysms, are summarized with a focus on flow diverters for these pathologies. Finally, we discuss future directions in flow diversion technology including bioresorbable flow diverters, transcriptomics and radiogenomics, and machine learning and artificial intelligence. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Hypertension and intracerebral hemorrhage recurrence among white, black, and Hispanic individuals

Author

Rodriguez-Torres, Axana, Murphy, Meredith, Kourkoulis, Christina, Schwab, Kristin, Ayres, Alison M., Moomaw, Charles J., Young Kwon, Soo, Berthaud, Jimmy V., Gurol, M. Edip, Greenberg, Steven M., Viswanathan, Anand, Anderson, Christopher D., Flaherty, Matthew, James, Michael L., Birnbaum, Lee, Yong Sung, Gene, Parikh, Gunjan, Boehme, Amelia K., Mayson, Douglas, Sheth, Kevin N., Kidwell, Chelsea, Koch, Sebastian, Frankel, Michael, Langefeld, Carl D., Testai, Fernando D., Woo, Daniel, Rosand, Jonathan, and Biffi, Alessandro

Published
2018
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26. Technical and clinical success after venous sinus stenting for treatment of idiopathic intracranial hypertension using a novel guide catheter for access: Case series and initial multi-center experience

Author

Zyck, Stephanie, primary, Malik, Muhammad, additional, Webb, Matthew, additional, Mohammed, Marwa, additional, Powers, Ciaran J, additional, Birnbaum, Lee, additional, Hawk, Harris, additional, Brinjikji, Waleed, additional, and Nimjee, Shahid M., additional

Published
2022
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27. Endovascular therapy versus microsurgical clipping of unruptured wide-neck aneurysms: a prospective multicenter study with propensity score analysis

Author

Mascitelli, Justin R., primary, Mocco, J, additional, Hardigan, Trevor, additional, Hendricks, Benjamin K., additional, Yoon, James S., additional, Yaeger, Kurt A., additional, Kellner, Christopher P., additional, De Leacy, Reade A., additional, Fifi, Johanna T., additional, Bederson, Joshua B., additional, Albuquerque, Felipe C., additional, Ducruet, Andrew F., additional, Birnbaum, Lee A., additional, Caron, Jean Louis R., additional, Rodriguez, Pavel, additional, and Lawton, Michael T., additional

Published
2022
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28. Endovascular Therapy Versus Microsurgical Clipping of Ruptured Wide Neck Aneurysms (EVERRUN Registry): a multicenter, prospective propensity score analysis

Author

Mascitelli, Justin R., primary, Lawton, Michael T., additional, Hendricks, Benjamin K., additional, Hardigan, Trevor A., additional, Yoon, James S., additional, Yaeger, Kurt A., additional, Kellner, Christopher P., additional, De Leacy, Reade A., additional, Fifi, Johanna T., additional, Bederson, Joshua B., additional, Albuquerque, Felipe C., additional, Ducruet, Andrew F., additional, Birnbaum, Lee A., additional, Caron, Jean Louis R., additional, Rodriguez, Pavel, additional, and Mocco, J, additional

Published
2022
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31. Risk Factors Associated With Mortality and Neurologic Disability After Intracerebral Hemorrhage in a Racially and Ethnically Diverse Cohort

Author

Woo, Daniel, primary, Comeau, Mary E., additional, Venema, Simone Uniken, additional, Anderson, Christopher D., additional, Flaherty, Matthew, additional, Testai, Fernando, additional, Kittner, Steven, additional, Frankel, Michael, additional, James, Michael L., additional, Sung, Gene, additional, Elkind, Mitchell, additional, Worrall, Bradford, additional, Kidwell, Chelsea, additional, Gonzales, Nicole, additional, Koch, Sebastian, additional, Hall, Christiana, additional, Birnbaum, Lee, additional, Mayson, Douglas, additional, Coull, Bruce, additional, Malkoff, Marc, additional, Sheth, Kevin N., additional, McCauley, Jacob L., additional, Osborne, Jennifer, additional, Morgan, Misty, additional, Gilkerson, Lee, additional, Behymer, Tyler, additional, Coleman, Elisheva R., additional, Rosand, Jonathan, additional, Sekar, Padmini, additional, Moomaw, Charles J., additional, and Langefeld, Carl D., additional

Published
2022
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33. Management of a fractured microcatheter during middle meningeal artery embolization.

Author

Webb, Matthew, Anqi Luo, Al Saiegh, Fadi, Birnbaum, Lee, Gragnaniello, Cristian, and Mascitelli, Justin R.

Subjects
THERAPEUTIC embolization, SURGICAL stents, RESPIRATORY aspiration, ANGIOGRAPHY, CATHETERS, SUBDURAL hematoma, RETAINED surgical items, MENINGEAL artery
Abstract

Middle meningeal artery embolization (MMAE) is an effective adjunctive treatment for chronic subdural hematomas and carries a low risk of significant complications. Here we describe the management of a retained and fractured microcatheter following liquid embolic MMAE. A patient with chronic recurrent subdural hematomas underwent bilateral MMAE with Onyx liquid embolic material (Medtronic). The Headway Duo (Microvention) microcatheter was placed in a small distal frontal branch of the middle meningeal artery to aid in reflux into the posterior middle meningeal artery branches. Following successful MMAE, the micro- catheter became trapped within the Onyx cast and, on attempted removal, the microcatheter fractured, resulting in a retained fragment extending from the middle meningeal artery cast to the guide catheter in the common carotid artery. To retrieve the fractured microcatheter, a stent retriever was deployed and resheathed multiple times until the retained microcatheter became visibly entangled with the stent retriever. Next, the stent retriever was pulled back into the guide catheter and continuous aspiration was performed through the guide catheter, and the fragmented microcatheter was successfully removed in entirety. Final angiography demonstrated no further catheter fragments, vessel damage, extravasation, flow limitation, or thromboembolic complications. Methods to avoid the complication include using a detachable tip microcatheter, dual lumen balloon microcatheter, allowing less reflux, embolizing from a larger caliber branch, and a slower micro- catheter pull. Additional methods for managing the complication include using a snare, leaving the retained microcatheter and putting the patient on aspirin, and carotid stenting to tack the fractured portion down (video 1). This case demonstrates the successful use of a stent retriever and aspiration to retrieve a retained and fractured microcatheter following liquid embolic MMAE. [ABSTRACT FROM AUTHOR]

Published
2024
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43. Global impact of COVID-19 on stroke care

Author

Nogueira, Raul G., Abdalkader, Mohamad, Qureshi, Muhammed M., Frankel, Michael R., Mansour, Ossama Yassin, Yamagami, Hiroshi, Qiu, Zhongming, Farhoudi, Mehdi, Siegler, James E, Yaghi, Shadi, Raz, Eytan, Sakai, Nobuyuki, Ohara, Nobuyuki, Piotin, Michel, Mechtouff, Laura, Eker, Omer, Chalumeau, Vanessa, Kleinig, Timothy J., Pop, Raoul, Liu, Jianmin, Winters, Hugh S., Shang, Xianjin, Rodriguez Vasquez, Alejandro, Blasco, Jordi, Arenillas, Juan F, Martinez-Galdamez, Mario, Brehm, Alex, Psychogios, Marios-Nikos, Lylyk, Pedro, Haussen, Diogo C., Al-Bayati, Alhamza R., Mohammaden, Mahmoud H., Fonseca, Luísa, Luís Silva, M., Montalverne, Francisco, Renieri, Leonardo, Mangiafico, Salvatore, Fischer, Urs, Gralla, Jan, Frei, Donald, Chugh, Chandril, Mehta, Brijesh P., Nagel, Simon, Mohlenbruch, Markus, Ortega-Gutierrez, Santiago, Farooqui, Mudassir, Hassan, Ameer E, Taylor, Allan, Lapergue, Bertrand, Consoli, Arturo, Campbell, Bruce C.V., Sharma, Malveeka, Walker, Melanie, Van Horn, Noel, Fiehler, Jens, Nguyen, Huy Thang, Nguyen, Quoc T., Watanabe, Daisuke, Zhang, Hao, Le, Huynh V., Nguyen, Viet Q., Shah, Ruchir, Devlin, Thomas, Khandelwal, Priyank, Linfante, Italo, Izzath, Wazim, Lavados, Pablo M., Olavarría, Veronica V., Sampaio Silva, Gisele, de Carvalho Sousa, Anna Verena, Kirmani, Jawad, Bendszus, Martin, Amano, Tatsuo, Yamamoto, Ryoo, Doijiri, Ryosuke, Tokuda, Naoki, Yamada, Takehiro, Terasaki, Tadashi, Yazawa, Yukako, Morris, Jane G., Griffin, Emma, Thornton, John, Lavoie, Pascale, Matouk, Charles, Hill, M. D, Demchuk, Andrew M., Killer-Oberpfalzer, Monika, Nahab, Fadi, Altschul, Dorothea, Ramos-Pachón, Anna, Pérez de la Ossa, Natalia, Kikano, Raghid, Boisseau, William, Walker, Gregory, Cordina, Steve M., Puri, Ajit, Luisa Kuhn, Anna, Gandhi, Dheeraj, Ramakrishnan, Pankajavalli, Novakovic-White, Roberta, Chebl, Alex, Kargiotis, Odysseas, Czap, Alexandra L, Zha, Alicia M, Masoud, Hesham E., Lopez, Carlos, Ozretic, David, Al-Mufti, Fawaz, Zie, Wenjie, Duan, Zhenhui, Yuan, Zhengzhou, Huang, Wenguo, Hao, Yonggang, Luo, Jun, Kalousek, Vladimir, Bourcier, Romain, Guile, Romain, Hetts, Steven, Al-Jehani, Hosam M., AlHazzani, Adel, Sadeghi-Hokmabadi, Elyar, Teleb, Mohamed, Payne, Jeremy, Lee, Jin Soo, Hong, Ji Man, Sohn, Sung-Il, Hwang, Yang-Ha, Shin, Dong Hoon, Roh, Hong Gee, Edgell, Randy, Khatri, Rakesh, Smith, Ainsley, Malik, Amer, Liebeskind, David, Herial, Nabeel, Jabbour, Pascal, Magalhaes, Pedro, Ozdemir, Atilla Ozcan, Aykac, Ozlem, Uwatoko, Takeshi, Dembo, Tomohisa, Shimizu, Hisao, Sugiura, Yuri, Miyashita, Fumio, Fukuda, Hiroki, Miyake, Kosuke, Shimbo, Junsuke, Sugimura, Yusuke, Beer-Furlan, Andre, Joshi, Krishna, Catanese, Luciana, Abud, Daniel Giansante, Neto, Octavio Giansante, Mehrpour, Masoud, Al Hashmi, Amal, Saqqur, Mahar, Mostafa, Abdulrahman, Fifi, Johanna T., Hussain, Syed, John, Seby, Gupta, Rishi, Sivan-Hoffmann, Rotem, Reznik, Anna, Sani, Achmad Fidaus, Geyik, Serdar, Akıl, Eşref, Churojana, Anchalee, Ghoreishi, Abdoreza, Saadatnia, Mohammad, Sharifipour, Ehsan, Ma, Alice, Faulder, Ken, Wu, Teddy, Leung, Lester, Malek, Adel, Voetsch, Barbara, Wakhloo, Ajay, Rivera, Rodrigo, Barrientos Iman, Danny Moises, Pikula, Aleksandra, Lioutas, Vasileios-Arsenios, Thomalla, Gotz, Birnbaum, Lee, Machi, Paolo, Bernava, Gianmarco, McDermott, Mollie, Kleindorfer, Dawn, Wong, Ken, Patterson, Mary S., Fiorot, Jose Antonio, Huded, Vikram, Mack, William, Tenser, Matthew, Eskey, Clifford, Multani, Sumeet, Kelly, Michael, Janardhan, Vallabh, Cornett, Oriana, Singh, Varsha, Murayama, Yuichi, Mokin, Maxim, Yang, Pengfei, Zhang, Xiaoxi, Yin, Congguo, Han, Hongxing, Peng, Ya, Chen, Wenhuo, Crosa, Roberto, Frudit, Michel E., Pandian, Jeyaraj D., Kulkarni, Anirudh, Yagita, Yoshiki, Takenobu, Yohei, Matsumaru, Yuji, Yamada, Satoshi, Kono, Ryuhei, Kanamaru, Takuya, Yamazaki, Hidekazu, Sakaguchi, Manabu, Todo, Kenichi, Yamamoto, Nobuaki, Sonoda, Kazutaka, Yoshida, Tomoko, Hashimoto, Hiroyuki, Nakahara, Ichiro, Cora, Elena, Volders, David, Ducroux, Celina, Shoamanesh, Ashkan, Ospel, Johanna, Kaliaev, Artem, Ahmed, Saima, Rashid, Umair, Rebello, Leticia C., Pereira, Vitor Mendes, Fahed, Robert, Chen, Michael, Sheth, Sunil A., Palaiodimou, Lina, Tsivgoulis, Georgios, Chandra, Ronil, Koyfman, Feliks, Leung, Thomas, Khosravani, Houman, Dharmadhikari, Sushrut, Frisullo, Giovanni, Calabresi, Paolo, Tsiskaridze, Alexander, Lobjanidze, Nino, Grigoryan, Mikayel, Czlonkowska, Anna, de Sousa, Diana A., Demeestere, Jelle, Liang, Conrad, Sangha, Navdeep, Lutsep, Helmi L., Ayo-Martín, Óscar, Cruz-Culebras, Antonio, Tran, Anh D., Young, Chang Y., Cordonnier, Charlotte, Caparros, Francois, De Lecinana, Maria Alonso, Fuentes, Blanca, Yavagal, Dileep, Jovin, Tudor, Spelle, Laurent, Moret, Jacques, Khatri, Pooja, Zaidat, Osama, Raymond, Jean, Martins, Sheila, Nguyen, Thanh N, Universitat Autònoma de Barcelona, and UAM. Departamento de Medicina

Subjects
Gerontology, 2019-20 coronavirus outbreak, medicine.medical_specialty, acute ischemic stroke, Hospitals, Low-Volume, Time Factors, Coronavirus disease 2019 (COVID-19), Medicina, Clinical Neurology, Stroke care, stroke care, Global Health, mechanical thrombectomy, Pandemic, Epidemiology, Health care, Global health, Medicine, Humans, Registries, Stroke, Retrospective Studies, Thrombectomy, Science & Technology, business.industry, Research, COVID-19, medicine.disease, Hospitalization, Cross-Sectional Studies, Peripheral Vascular Disease, Neurology, Cardiovascular System & Cardiology, epidemiology, Neurosciences & Neurology, business, Life Sciences & Biomedicine, Intracranial Hemorrhages, Hospitals, High-Volume, intracranial hemorrhage
Abstract

Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM, Background: The COVID-19 pandemic led to profound changes in the organization of health care systems worldwide. Aims: We sought to measure the global impact of the COVID-19 pandemic on the volumes for mechanical thrombectomy, stroke, and intracranial hemorrhage hospitalizations over a three-month period at the height of the pandemic (1 March–31 May 2020) compared with two control three-month periods (immediately preceding and one year prior). Methods: Retrospective, observational, international study, across 6 continents, 40 countries, and 187 comprehensive stroke centers. The diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases at participating centers. Results: The hospitalization volumes for any stroke, intracranial hemorrhage, and mechanical thrombectomy were 26,699, 4002, and 5191 in the three months immediately before versus 21,576, 3540, and 4533 during the first three pandemic months, representing declines of 19.2% (95%CI, −19.7 to −18.7), 11.5% (95%CI, −12.6 to −10.6), and 12.7% (95%CI, −13.6 to −11.8), respectively. The decreases were noted across centers with high, mid, and low COVID-19 hospitalization burden, and also across high, mid, and low volume stroke/mechanical thrombectomy centers. High-volume COVID-19 centers (−20.5%) had greater declines in mechanical thrombectomy volumes than mid- (−10.1%) and low-volume (−8.7%) centers (p < 0.0001). There was a 1.5% stroke rate across 54,366 COVID-19 hospitalizations. SARS-CoV-2 infection was noted in 3.9% (784/20,250) of all stroke admissions. Conclusion: The COVID-19 pandemic was associated with a global decline in the volume of overall stroke hospitalizations, mechanical thrombectomy procedures, and intracranial hemorrhage admission volumes. Despite geographic variations, these volume reductions were observed regardless of COVID-19 hospitalization burden and pre-pandemic stroke/mechanical thrombectomy volumes

Published
2021

44. Ethnic and Racial Variation in Intracerebral Hemorrhage Risk Factors and Risk Factor Burden

Author

Kittner, Steven J., primary, Sekar, Padmini, additional, Comeau, Mary E., additional, Anderson, Christopher D., additional, Parikh, Gunjan Y., additional, Tavarez, Tachira, additional, Flaherty, Matthew L., additional, Testai, Fernando D., additional, Frankel, Michael R., additional, James, Michael L., additional, Sung, Gene, additional, Elkind, Mitchell S. V., additional, Worrall, Bradford B., additional, Kidwell, Chelsea S., additional, Gonzales, Nicole R., additional, Koch, Sebastian, additional, Hall, Christiana E., additional, Birnbaum, Lee, additional, Mayson, Douglas, additional, Coull, Bruce, additional, Malkoff, Marc D., additional, Sheth, Kevin N., additional, McCauley, Jacob L., additional, Osborne, Jennifer, additional, Morgan, Misty, additional, Gilkerson, Lee A., additional, Behymer, Tyler P., additional, Demel, Stacie L., additional, Moomaw, Charles J., additional, Rosand, Jonathan, additional, Langefeld, Carl D., additional, and Woo, Daniel, additional

Published
2021
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46. The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) Study Protocol

Author

Woo, Daniel, Rosand, Jonathan, Kidwell, Chelsea, McCauley, Jacob L., Osborne, Jennifer, Brown, Mark W., West, Sandra E., Rademacher, Eric W., Waddy, Salina, Roberts, Jamie N., Koch, Sebastian, Gonzales, Nicole R., Sung, Gene, Kittner, Steven J., Birnbaum, Lee, Frankel, Michael, Testai, Fernando Daniel, Hall, Christiana E., Elkind, Mitchell S.V., Flaherty, Matthew, Coull, Bruce, Chong, Ji Y., Warwick, Tanya, Malkoff, Marc, James, Michael L., Ali, Latisha K., Worrall, Bradford B., Jones, Floyd, Watson, Tiffany, Leonard, Anne, Martinez, Rebecca, Sacco, Ralph I., and Langefeld, Carl D.

Published
2013
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48. Paramedic utilization of Vision, Aphasia, Neglect (VAN) stroke severity scale in the prehospital setting predicts emergent large vessel occlusion stroke

Author

Birnbaum, Lee, primary, Wampler, David, additional, Shadman, Arash, additional, de Leonni Stanonik, Mateja, additional, Patterson, Michele, additional, Kidd, Emily, additional, Tovar, Jeanette, additional, Garza, Ashley, additional, Blanchard, Bonnie, additional, Slesnick, Lara, additional, Blanchette, Adam, additional, and Miramontes, David, additional

Published
2020
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50. Abstract TP262: Pre-Hospital VAN Large Vessel Occlusion Screening Tool Predicts Larger Intracerebral Hemorrhage

Author

Shadman, Arash, primary, Mozumder, Aaisha, additional, de Leonni Stanonik, Mateja, additional, Patterson, Michele, additional, Wampler, David, additional, Stringfellow, Michael, additional, Kidd, Emily, additional, Miramontes, David, additional, Cope, Steven, additional, Baker, Cheryl, additional, Blanchette, Adam, additional, and Birnbaum, Lee, additional

Published
2020
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