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6 results on '"Birch, Philippa"'

1. Neuropsychiatric risk in children with intellectual disability of genetic origin: IMAGINE, a UK national cohort study

Author

Wolstencroft, Jeanne, Wicks, Francesca, Srinivasan, Ramya, Erwood, Marie, Lafont, Amy, Timur, Husne, Ye, Zheng, Walker, Susan, Printzlau, Frida, Juj, Manoj, Davies, Sarah, Denyer, Hayley, Watkins, Alice, Kerry, Eleanor, Coscini, Nadia, Fatih, Nasrtullah, Lucock, Anna, Denaxas, Spiros, Mandy, William, Walker, Neil, Wallwork, Sarah, Dewhurst, Eleanor, Cuthbert, Andrew, Challenger, Aimee, Andrews, Sophie, Holmans, Peter, Bowen, Samantha, Bradley, Karen, Birch, Philippa, Tong, Molly, Lewis, Nicola, Ray, Sinead, Sopp, Matthew, Moss, Hayley, Wynn, Sarah, Searle, Beverley, Robertson, Lisa, Berg, Jonathan, Lampe, Anne, Joss, Shelagh, Brennan, Paul, Kraus, Alison, Lahiri, Nayana, Weber, Astrid, Rawson, Myfanwy, Johnson, Diana, Vasudevan, Pradeep, Harrison, Rachel, Williams, Denise, Maher, Eamonn, Kini, Usha, Van Dijk, Fleur, Clowes, Virginia, Gurasashvilli, Jana, Mansour, Sahar, Holder-Espinasse, Muriel, Watford, Amy, Rankin, Julia, Baralle, Diana, Procter, Annie, Ford, Tamsin, Baker, Kate, Chawner, Samuel, Hall, Jeremy, Van den Bree, Marianne B M, Owen, Michael J, Skuse, David, Raymond, F Lucy, Chawner, Samuel J R A, and van den Bree, Marianne B M

Published
2022
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2. White Matter Microstructure in Youths With Conduct Disorder: Effects of Sex and Variation in Callous Traits

Author

Rogers, Jack C., Gonzalez-Madruga, Karen, Kohls, Gregor, Baker, Rosalind H., Clanton, Roberta L., Pauli, Ruth, Birch, Philippa, Chowdhury, Alimul I., Kirchner, Marietta, Andersson, Jesper L.R., Smaragdi, Areti, Puzzo, Ignazio, Baumann, Sarah, Raschle, Nora M., Fehlbaum, Lynn V., Menks, Willeke M., Steppan, Martin, Stadler, Christina, Konrad, Kerstin, Freitag, Christine M., Fairchild, Graeme, and De Brito, Stephane A.

Published
2019
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4. Positive and negative parenting in conduct disorder with high versus low levels of callous–unemotional traits

Author

Pauli, Ruth, primary, Tino, Peter, additional, Rogers, Jack C., additional, Baker, Rosalind, additional, Clanton, Roberta, additional, Birch, Philippa, additional, Brown, Abigail, additional, Daniel, Gemma, additional, Ferreira, Lisandra, additional, Grisley, Liam, additional, Kohls, Gregor, additional, Baumann, Sarah, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Ackermann, Katharina, additional, Lazaratou, Helen, additional, Tsiakoulia, Foteini, additional, Bali, Panagiota, additional, Oldenhof, Helena, additional, Jansen, Lucres, additional, Smaragdi, Areti, additional, Gonzalez-Madruga, Karen, additional, Gonzalez-Torres, Miguel Angel, additional, Gonzalez de Artaza-Lavesa, Maider, additional, Steppan, Martin, additional, Vriends, Noortje, additional, Bigorra, Aitana, additional, Siklosi, Reka, additional, Ghosh, Sreejita, additional, Bunte, Kerstin, additional, Dochnal, Roberta, additional, Hervas, Amaia, additional, Stadler, Christina, additional, Fernandez-Rivas, Aranzazu, additional, Fairchild, Graeme, additional, Popma, Arne, additional, Dikeos, Dimitris, additional, Konrad, Kerstin, additional, Herpertz-Dahlmann, Beate, additional, Freitag, Christine M., additional, Rotshtein, Pia, additional, and De Brito, Stephane A., additional

Published
2020
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5. Positive and negative parenting in conduct disorder with high versus low levels of callous–unemotional traits.

Author

Pauli, Ruth, Tino, Peter, Rogers, Jack C., Baker, Rosalind, Clanton, Roberta, Birch, Philippa, Brown, Abigail, Daniel, Gemma, Ferreira, Lisandra, Grisley, Liam, Kohls, Gregor, Baumann, Sarah, Bernhard, Anka, Martinelli, Anne, Ackermann, Katharina, Lazaratou, Helen, Tsiakoulia, Foteini, Bali, Panagiota, Oldenhof, Helena, and Jansen, Lucres

Abstract

Less is known about the relationship between conduct disorder (CD), callous–unemotional (CU) traits, and positive and negative parenting in youth compared to early childhood. We combined traditional univariate analyses with a novel machine learning classifier (Angle-based Generalized Matrix Learning Vector Quantization) to classify youth (N = 756; 9–18 years) into typically developing (TD) or CD groups with or without elevated CU traits (CD/HCU, CD/LCU, respectively) using youth- and parent-reports of parenting behavior. At the group level, both CD/HCU and CD/LCU were associated with high negative and low positive parenting relative to TD. However, only positive parenting differed between the CD/HCU and CD/LCU groups. In classification analyses, performance was best when distinguishing CD/HCU from TD groups and poorest when distinguishing CD/HCU from CD/LCU groups. Positive and negative parenting were both relevant when distinguishing CD/HCU from TD, negative parenting was most relevant when distinguishing between CD/LCU and TD, and positive parenting was most relevant when distinguishing CD/HCU from CD/LCU groups. These findings suggest that while positive parenting distinguishes between CD/HCU and CD/LCU, negative parenting is associated with both CD subtypes. These results highlight the importance of considering multiple parenting behaviors in CD with varying levels of CU traits in late childhood/adolescence. [ABSTRACT FROM AUTHOR]

Published
2021
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6. White Matter Microstructure in Youths With Conduct Disorder: Effects of Sex and Variation in Callous Traits

Author

Rogers, Jack C, Gonzalez-Madruga, Karen, Kohls, Gregor, Baker, Rosalind H, Clanton, Roberta L, Pauli, Ruth, Birch, Philippa, Chowdhury, Alimul I, Kirchner, Marietta, Andersson, Jesper L R, Smaragdi, Areti, Puzzo, Ignazio, Baumann, Sarah, Raschle, Nora Maria; https://orcid.org/0000-0002-3160-5999, Fehlbaum, Lynn V, Menks, Willeke M, Steppan, Martin, Stadler, Christina, Konrad, Kerstin, Freitag, Christine M, Fairchild, Graeme, De Brito, Stephane A, Rogers, Jack C, Gonzalez-Madruga, Karen, Kohls, Gregor, Baker, Rosalind H, Clanton, Roberta L, Pauli, Ruth, Birch, Philippa, Chowdhury, Alimul I, Kirchner, Marietta, Andersson, Jesper L R, Smaragdi, Areti, Puzzo, Ignazio, Baumann, Sarah, Raschle, Nora Maria; https://orcid.org/0000-0002-3160-5999, Fehlbaum, Lynn V, Menks, Willeke M, Steppan, Martin, Stadler, Christina, Konrad, Kerstin, Freitag, Christine M, Fairchild, Graeme, and De Brito, Stephane A

Abstract

OBJECTIVE: Studies using diffusion tensor imaging (DTI) to investigate white matter (WM) microstructure in youths with conduct disorder (CD) have reported disparate findings. We investigated WM alterations in a large sample of youths with CD, and examined the influence of sex and callous-unemotional (CU) traits. METHOD: DTI data were acquired from 124 youths with CD (59 female) and 174 typically developing (TD) youths (103 female) 9 to 18 years of age. Tract-based spatial statistics tested for effects of diagnosis and sex-by-diagnosis interactions. Associations with CD symptoms, CU traits, a task measuring impulsivity, and the impact of comorbidity, and age- and puberty-related effects were examined. RESULTS: Youths with CD exhibited higher axial diffusivity in the corpus callosum and lower radial diffusivity and mean diffusivity in the anterior thalamic radiation relative to TD youths. Female and male youths with CD exhibited opposite changes in the left hemisphere within the internal capsule, fornix, posterior thalamic radiation, and uncinate fasciculus. Within the CD group, CD symptoms and callous traits exerted opposing influences on corpus callosum axial diffusivity, with callous traits identified as the unique clinical feature predicting higher axial diffusivity and lower radial diffusivity within the corpus callosum and anterior thalamic radiation, respectively. In an exploratory analysis, corpus callosum axial diffusivity partially mediated the association between callous traits and impulsive responses to emotional faces. Results were not influenced by symptoms of comorbid disorders, and no age- or puberty-related interactions were observed. CONCLUSION: WM alterations within the corpus callosum represent a reliable neuroimaging marker of CD. Sex and callous traits are important factors to consider when examining WM in CD.

Published
2019

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