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36 results on '"Bijnens, Esmée M."'

4. Methylome-wide analysis of IVF neonates that underwent embryo culture in different media revealed no significant differences

Author

Koeck, Rebekka M., Busato, Florence, Tost, Jorg, Consten, Dimitri, van Echten-Arends, Jannie, Mastenbroek, Sebastiaan, Wurth, Yvonne, Remy, Sylvie, Langie, Sabine, Nawrot, Tim S., Plusquin, Michelle, Alfano, Rossella, Bijnens, Esmée M., Gielen, Marij, van Golde, Ron, Dumoulin, John C. M., Brunner, Han, van Montfoort, Aafke P. A., and Zamani Esteki, Masoud

Published
2022
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8. Pre-admission air pollution exposure prolongs the duration of ventilation in intensive care patients

Author

De Weerdt, Annick, Janssen, Bram G., Cox, Bianca, Bijnens, Esmée M., Vanpoucke, Charlotte, Lefebvre, Wouter, and El Salawi, Omar

Subjects
Pollutants -- Analysis, Nitrogen dioxide -- Analysis, Lung diseases -- Risk factors, Medical records -- Analysis, Air pollution -- Analysis, Hospital patients -- Analysis, Health care industry
Abstract

Purpose Air pollutant exposure constitutes a serious risk factor for the emergence or aggravation of (existing) pulmonary disease. The impact of pre-intensive care ambient air pollutant exposure on the duration of artificial ventilation was, however, not yet established. Methods The medical records of 2003 patients, admitted to the intensive care unit (ICU) of the Antwerp University Hospital (Flanders, Belgium), who were artificially ventilated on ICU admission or within 48 h after admission, for the duration of at least 48 h, were analyzed. For each patient's home address, daily air pollutant exposure [particulate matter with an aerodynamic diameter [less than or equal to] 2.5 [micro]m (PM.sub.2.5) and [less than or equal to] 10 [micro]m (PM.sub.10), nitrogen dioxide (NO.sub.2) and black carbon (BC)] up to 10 days prior to hospital admission was modeled using a high-resolution spatial-temporal model. The association between duration of artificial ventilation and air pollution exposure during the last 10 days before ICU admission was assessed using distributed lag models with a negative binomial regression fit. Results Controlling for pre-specified confounders, an IQR increment in BC (1.2 [micro]g/m.sup.3) up to 10 days before admission was associated with an estimated cumulative increase of 12.4% in ventilation duration (95% CI 4.7-20.7). Significant associations were also observed for PM.sub.2.5, PM.sub.10 and NO.sub.2, with cumulative estimates ranging from 7.8 to 8.0%. Conclusion Short-term ambient air pollution exposure prior to ICU admission represents an unrecognized environmental risk factor for the duration of artificial ventilation in the ICU., Author(s): Annick De Weerdt [sup.1] [sup.2], Bram G. Janssen [sup.3], Bianca Cox [sup.3], Esmée M. Bijnens [sup.3], Charlotte Vanpoucke [sup.4], Wouter Lefebvre [sup.5], Omar El Salawi [sup.2], Margot Jans [sup.2], [...]

Published
2020
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9. Pre-admission ambient air pollution and blood soot particles predict hospitalisation outcomes in COVID-19 patients

Author

Vos, Stijn, primary, De Waele, Elien, additional, Goeminne, Pieter, additional, Bijnens, Esmée M., additional, Bongaerts, Eva, additional, Martens, Dries S., additional, Malina, Robert, additional, Ameloot, Marcel, additional, Dams, Karolien, additional, De Weerdt, Annick, additional, Dewyspelaere, Geert, additional, Jacobs, Rita, additional, Mistiaen, Geert, additional, Jorens, Philippe, additional, and Nawrot, Tim S., additional

Published
2023
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16. Higher proportion of agricultural land use around the residence is associated with higher urinary concentrations of AMPA, a glyphosate metabolite

Author

De Troeyer, Katrien, primary, Casas, Lidia, additional, Bijnens, Esmée M, additional, Bruckers, Liesbeth, additional, Covaci, Adrian, additional, De Henauw, Stefaan, additional, Den Hond, Elly, additional, Loots, Ilse, additional, Nelen, Vera, additional, Verheyen, Veerle J, additional, Vos, Stijn, additional, Schoeters, Greet, additional, Hoppe, Hans-Wolfgang, additional, Köster, Helmut Dietrich, additional, and Nawrot, Tim S, additional

Published
2022
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19. Indoor green can modify the indoor dust microbial communities

Author

Dockx, Yinthe, primary, Täubel, Martin, additional, Bijnens, Esmée M., additional, Witters, Katrien, additional, Valkonen, Maria, additional, Jayaprakash, Balamuralikrishna, additional, Hogervorst, Janneke, additional, Nawrot, Tim S., additional, and Casas, Lidia, additional

Published
2022
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22. Determinants of Chronic Biological Stress, Measured as Hair Cortisol Concentration, in a General Population of Adolescents: From Individual and Household Characteristics to Neighborhood Urbanicity

Author

Verheyen, Veerle J., primary, Remy, Sylvie, additional, Govarts, Eva, additional, Colles, Ann, additional, Koppen, Gudrun, additional, Martin, Laura Rodriguez, additional, Nielsen, Flemming, additional, Bruckers, Liesbeth, additional, Bijnens, Esmée M., additional, Vos, Stijn, additional, Morrens, Bert, additional, Coertjens, Dries, additional, Loots, Ilse, additional, De Decker, Annelies, additional, Franken, Carmen, additional, Den Hond, Elly, additional, Nelen, Vera, additional, De Henauw, Stefaan, additional, Covaci, Adrian, additional, Van Larebeke, Nicolas, additional, Teughels, Caroline, additional, Nawrot, Tim S., additional, and Schoeters, Greet, additional

Published
2021
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24. Long-term residential exposure to air pollution is associated with hair cortisol concentration and differential leucocyte count in Flemish adolescent boys

Author

Verheyen, Veerle J., primary, Remy, Sylvie, additional, Bijnens, Esmée M., additional, Colles, Ann, additional, Govarts, Eva, additional, Martin, Laura Rodriguez, additional, Koppen, Gudrun, additional, Bruckers, Liesbeth, additional, Nielsen, Flemming, additional, Vos, Stijn, additional, Morrens, Bert, additional, Coertjens, Dries, additional, De Decker, Annelies, additional, Franken, Carmen, additional, Den Hond, Elly, additional, Nelen, Vera, additional, Covaci, Adrian, additional, Loots, Ilse, additional, De Henauw, Stefaan, additional, van Larebeke, Nicolas, additional, Teughels, Caroline, additional, Nawrot, Tim S., additional, and Schoeters, Greet, additional

Published
2021
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31. Left ventricular function in relation to chronic residential air pollution in a general population

Author

Yang, Wen-Yi, primary, Zhang, Zhen-Yu, additional, Thijs, Lutgarde, additional, Bijnens, Esmée M, additional, Janssen, Bram G, additional, Vanpoucke, Charlotte, additional, Lefebvre, Wouter, additional, Cauwenberghs, Nicholas, additional, Wei, Fang-Fei, additional, Luttun, Aernout, additional, Verhamme, Peter, additional, Van Hecke, Etienne, additional, Kuznetsova, Tatiana, additional, D’hooge, Jan, additional, Nawrot, Tim S, additional, and Staessen, Jan A, additional

Published
2017
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33. An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe

Author

Ruttens, David, primary, Verleden, Stijn E., additional, Bijnens, Esmée M., additional, Winckelmans, Ellen, additional, Gottlieb, Jens, additional, Warnecke, Gregor, additional, Meloni, Federica, additional, Morosini, Monica, additional, Van Der Bij, Wim, additional, Verschuuren, Erik A., additional, Sommerwerck, Urte, additional, Weinreich, Gerhard, additional, Kamler, Markus, additional, Roman, Antonio, additional, Gomez-Olles, Susana, additional, Berastegui, Cristina, additional, Benden, Christian, additional, Holm, Are Martin, additional, Iversen, Martin, additional, Schultz, Hans Henrik, additional, Luijk, Bart, additional, Oudijk, Erik-Jan, additional, Kwakkel-van Erp, Johanna M., additional, Jaksch, Peter, additional, Klepetko, Walter, additional, Kneidinger, Nikolaus, additional, Neurohr, Claus, additional, Corris, Paul, additional, Fisher, Andrew J., additional, Lordan, James, additional, Meachery, Gerard, additional, Piloni, Davide, additional, Vandermeulen, Elly, additional, Bellon, Hannelore, additional, Hoffmann, Barbara, additional, Vienneau, Danielle, additional, Hoek, Gerard, additional, de Hoogh, Kees, additional, Nemery, Benoit, additional, Verleden, Geert M., additional, Vos, Robin, additional, Nawrot, Tim S., additional, and Vanaudenaerde, Bart M., additional

Published
2016
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34. Urinary Polycyclic Aromatic Hydrocarbon Metabolites Are Associated with Biomarkers of Chronic Endocrine Stress, Oxidative Stress, and Inflammation in Adolescents: FLEHS-4 (2016–2020).

Author

Verheyen, Veerle J., Remy, Sylvie, Govarts, Eva, Colles, Ann, Rodriguez Martin, Laura, Koppen, Gudrun, Voorspoels, Stefan, Bruckers, Liesbeth, Bijnens, Esmée M., Vos, Stijn, Morrens, Bert, Coertjens, Dries, De Decker, Annelies, Franken, Carmen, Den Hond, Elly, Nelen, Vera, Covaci, Adrian, Loots, Ilse, De Henauw, Stefaan, and Van Larebeke, Nicolas

Subjects
POLYCYCLIC aromatic hydrocarbons, PSYCHOLOGICAL stress, POLLUTANTS, OXIDATIVE stress, ADOLESCENCE, NEUTROPHIL lymphocyte ratio, LEUCOCYTES
Abstract

Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants of public health concern. Multiple biological mechanisms have been hypothesized to contribute to PAHs-associated adverse health effects. Little is known about the impact of PAHs on endocrine stress and inflammation in adolescence. We examined 393 Flemish adolescents (14–15 years) cross-sectionally, measured urinary concentrations of hydroxylated naphthalene, fluorene, phenanthrene and pyrene metabolites, and calculated the sum of all measured metabolites. We determined hair cortisol concentration (HCC) as endocrine stress biomarker, leucocyte counts and neutrophil–lymphocyte ratio (NLR) in peripheral blood as inflammatory biomarkers, and urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) concentration as oxidative stress biomarker. Exposure–response associations were analyzed by multiple regression, adjusted for a priori selected covariates. A doubling of 1-hydroxypyrene concentration was associated with a factor of 1.13 (95% CI: 1.03, 1.24) increase in HCC and a factor of 1.07 (95% CI: 1.02, 1.13) increase in 8-oxodG. Doublings of 2- and 3-hydroxyphenanthrene concentrations were associated with a factor of 1.08 (95% CI: 1.02, 1.14) and 1.06 (95% CI: 1.00, 1.12) increase in 8-oxodG, respectively. Doubling of 2-hydroxyphenanthrene and of the sum of 2- and 3-hydroxyfluorene was associated with, respectively, a factor of 1.08 (95% CI: 1.02, 1.14) and 1.06 (95% CI: 1.01, 1.13) increase in NLR. Our results indicate the glucocorticoid pathway as a potential target for PAH exposure in adolescents and suggest oxidative stress, endocrine stress, and inflammation in adolescence as underlying mechanisms and early markers for PAH-related adverse health effects. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Higher proportion of agricultural land use around the residence is associated with higher urinary concentrations of AMPA, a glyphosate metabolite.

Author

De Troeyer, Katrien, Casas, Lidia, Bijnens, Esmée M., Bruckers, Liesbeth, Covaci, Adrian, De Henauw, Stefaan, Den Hond, Elly, Loots, Ilse, Nelen, Vera, Verheyen, Veerle J., Vos, Stijn, Schoeters, Greet, Hoppe, Hans-Wolfgang, Köster, Helmut Dietrich, and Nawrot, Tim S.

Subjects
*HETEROCYCLIC compounds, *ENVIRONMENTAL exposure, *GLYPHOSATE, *AGRICULTURE
Abstract

Introduction: Pesticides, including herbicides, are widely used for agricultural and sanitary reasons and concerns have been raised about their various health effects. Little research has been done into the extent to which agricultural land use in the residential surroundings contributes to (internal) exposure of pesticides.Objectives: We investigated the associations between the proportion of agricultural land use around the residence and the exposure to pesticides in adolescents in Flanders (Belgium).Material and Methods: We included 424 adolescents participating in the fourth Flemish Environment and Health Study (FLEHS IV) between 2016 and 2020. The residential address of all participants was geocoded and the proportion of agricultural land use around the residence was estimated in several buffers (300 m, 500 m, 1000 m and 2000 m). The concentrations of the following biomarkers of pesticides were measured in urine and adjusted for the specific gravity: glyphosate and its metabolite, aminomethyl-phosphonic acid (AMPA); 3-phenoxybenzoic acid (3-PBA); 3,5,6-trichloro-2-pyridinol (TCPy) and 2,4-dichlophenoxy-acetic acid (2,4-D). We categorized the pesticide biomarkers in three categories according to the exposure levels and used ordinal logistic regression models adjusted for sex, season and household education to estimate the odds ratio for an increase in an interquartile range (IQR) of proportion of agricultural land use. We also used binary logistic regression models in which the category of highest exposure was compared to the category of lowest exposure. In addition, we explored potential effect modification by sex and season.Results: We found a significant association between the proportion of agricultural land use in a buffer of 2000 m around the residence and the levels of urinary AMPA divided into three categories (OR = 1.35 for an IQR increase in the proportion of agricultural land use around residence; 95% CI: 1.00-1.83). This association was less pronounced and not statistically significant for the other studied pesticides (OR ranging between 0.95 and 1.16). Stratified analysis showed the strongest association of the proportion of agricultural land use within 2000 m buffers for AMPA among boys (OR = 1.89; 95% CI: 1.19-3.04). Results using smaller buffers were comparable, but did not reach statistical significance.Conclusion: Our findings suggest that a higher proportion of agricultural land use around the residence might increase exposure to AMPA. [ABSTRACT FROM AUTHOR]

Published
2022
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36. An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe.

Author

Ruttens D, Verleden SE, Bijnens EM, Winckelmans E, Gottlieb J, Warnecke G, Meloni F, Morosini M, Van Der Bij W, Verschuuren EA, Sommerwerck U, Weinreich G, Kamler M, Roman A, Gomez-Olles S, Berastegui C, Benden C, Holm AM, Iversen M, Schultz HH, Luijk B, Oudijk EJ, Kwakkel-van Erp JM, Jaksch P, Klepetko W, Kneidinger N, Neurohr C, Corris P, Fisher AJ, Lordan J, Meachery G, Piloni D, Vandermeulen E, Bellon H, Hoffmann B, Vienneau D, Hoek G, de Hoogh K, Nemery B, Verleden GM, Vos R, Nawrot TS, and Vanaudenaerde BM

Subjects
Adult, Air Pollutants analysis, Cohort Studies, Europe epidemiology, Female, Graft Survival, Humans, Macrolides therapeutic use, Male, Middle Aged, Particulate Matter analysis, Proportional Hazards Models, Regression Analysis, Air Pollution adverse effects, Environmental Exposure adverse effects, Lung Transplantation mortality, Primary Graft Dysfunction physiopathology
Abstract

Air pollution from road traffic is a serious health risk, especially for susceptible individuals. Single-centre studies showed an association with chronic lung allograft dysfunction (CLAD) and survival after lung transplantation, but there are no large studies.13 lung transplant centres in 10 European countries created a cohort of 5707 patients. For each patient, we quantified residential particulate matter with aerodynamic diameter ≤10 µm (PM 10 ) by land use regression models, and the traffic exposure by quantifying total road length within buffer zones around the home addresses of patients and distance to a major road or freeway.After correction for macrolide use, we found associations between air pollution variables and CLAD/mortality. Given the important interaction with macrolides, we stratified according to macrolide use. No associations were observed in 2151 patients taking macrolides. However, in 3556 patients not taking macrolides, mortality was associated with PM 10 (hazard ratio 1.081, 95% CI 1.000-1.167); similarly, CLAD and mortality were associated with road lengths in buffers of 200-1000 and 100-500 m, respectively (hazard ratio 1.085- 1.130). Sensitivity analyses for various possible confounders confirmed the robustness of these associations.Long-term residential air pollution and traffic exposure were associated with CLAD and survival after lung transplantation, but only in patients not taking macrolides., (Copyright ©ERS 2017.)

Published
2017
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