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2. Context, Development, and Intent: An Introduction to the IPI Preservation Metrics

Author

Emma J. Richardson, Marvin Cummings, and Jean-Louis Bigourdan

Subjects
collections care, collecting institutions, preservation metrics, indoor climate, preservation environment, sustainable collections management, Archaeology, CC1-960
Abstract

Supporting collections care professionals and facilities managers to understand their preservation environments is of increasing importance as the field of cultural heritage grapples with the competing demands of environmental and financial sustainability and the desire to broaden access to collections. As such, the development of preservation indices that distill complex data into accessible tools can help collections care professionals understand the impact of access and preservation decisions and how they influence longevity. The IPI eClimateNotebook® Preservation Metrics were some of the earliest dose-response models developed for preservation, linking the rates of degradation and physical deformation to environmental variables and material properties. In this review article, we revisit the original aims and applications of the IPI Preservation Metrics with a view to aiding their interpretation and practical application for managing collection environments alongside a discussion of their limitations.

Published
2023
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4. Enhanced Absorption of Waves in Stealth Hyperuniform Disordered Media

Author

Bigourdan, Florian, Pierrat, Romain, and Carminati, Rémi

Subjects
Physics - Optics
Abstract

We study the propagation of waves in a set of absorbing subwavelength scatterers positioned on a stealth hyperuniform point pattern. We show that spatial correlations in the disorder substantially enhance absorption compared to a fully disordered structure with the same density of scatterers. The non-resonant nature of the mechanism provides broad angular and spectral robustness. These results demonstrate the possibility to design low-density materials with blackbody-like absorption.

Published
2018
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5. Non-occlusive Small Bowel Ischemia Related to Postoperative Feeding Jejunostomy Tube Use After Esophagectomy for Cancer: Propensity Score Analysis of the AFC-FREGAT Database

Author

Veziant, J., Gagnière, J., Gronnier, C., Mariette, C., Tzedakis, S., Fuks, D., Piessen, G., Luc, Guillaume, Cabau, Magalie, Jougon, Jacques, Badic, Bogdan, Lozach, Patrick, Cappeliez, Serge, Lebreton, Gil, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Iuga, Bogdan Stan, Contival, Nicolas, Pappalardo, Eric, Mantziari, Styliani, Hec, Flora, Vanderbeken, Marguerite, Tessier, Williams, Briez, Nicolas, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Bigourdan, Jean-Marc, Mezoughi, Salim, Ducerf, Christian, Baulieux, Jacques, Pasquer, Arnaud, Baraket, Oussama, Poncet, Gilles, Vaudoyer, Delphine, Enfer, Peggy Jourdan, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Petit, Gaelle Godiris, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Hannoun, Laurent, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, and Valleur, Patrice

Published
2022
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6. Vitamine D et ostéoporose. Étude de pratique à partir du Système National des Données de Santé en Occitanie.

Author

Bigourdan, Pauline and Birebent, Jordan

Abstract

Despite the absence of a pattern of use or not of vitamin D in osteoporotic patients by health authorities, vitamin D remains widely prescribed by doctors. This dissonance can give rise to inappropriate prescriptions. This study made it possible to take stock of the prescription of vitamin D in patients taking anti-osteoporotic drugs in Occitanie, as well as to evaluate the prescription methods for cholecalciferol. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Discussions on liquid bismuth target use as an alternative for astatine-211 production

Author

Bigourdan Théo, Cadiou Arnaud, Guertin Arnaud, and Haddad Ferid

Subjects
Physics, QC1-999
Abstract

Astatine-211 is an alpha emitter that has been identified as a good candidate for targeted alpha therapy. There is an increasing demand on this radionuclide. Very intense beam from linac being put in operation nowadays could be used to meet this demand. This document presents the design exploration of concepts of liquid bismuth targets dedicated to astatine-211 production. Three concepts are presented and analyzed: a capsule, a fluid loop and a windowless fluid loop. Structural and thermal sizing were performed using mechanical Finite Element models (ANSYS Workbench) and Computational Fluid Dynamic models (FLUENT). Production rates were assessed accordingly. Feasibility and expected performances are discussed in conclusion.

Published
2023
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11. Controlling spontaneous emission with plasmonic optical patch antennas

Author

Belacel, C., Habert, B., Bigourdan, F., Marquier, F., Hugonin, J. -P., de Vasconcellos, S. Michaelis, Lafosse, X., Coolen, L., Schwob, C., Javaux, C., Dubertret, B., Greffet, J. -J., Senellart, P., and Maitre, A.

Subjects
Quantum Physics, Condensed Matter - Other Condensed Matter, Physics - Optics
Abstract

We experimentally demonstrate the control of the spontaneous emission rate and the radiation pattern of colloidal quantum dots deterministically positioned in a plasmonic patch antenna. The antenna consists of a thin gold microdisk 30 nm above a thick gold layer. The emitters are shown to radiate through the entire patch antenna in a highly directional and vertical radiation pattern. Strong acceleration of spontaneous emission is observed, depending of the antenna size. Considering the double dipole structure of the emitters, this corresponds to a Purcell factor up to 80 for dipoles perpendicular to the disk.

Published
2012
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13. Surgically treated oesophageal cancer developed in a radiated field: Impact on peri-operative and long-term outcomes

Author

Luc, Guillaume, Cabau, Magalie, Jougon, Jacques, Badic, Bogdan, Lozach, Patrick, Cappeliez, Serge, Lebreton, Gil, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Stan Iuga, Bogdan, Contival, Nicolas, Pappalardo, Eric, Mantziari, Styliani, Hec, Flora, Vanderbeken, Marguerite, Tessier, Williams, Briez, Nicolas, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Bigourdan, Jean-Marc, Mezoughi, Salim, Ducerf, Christian, Baulieux, Jacques, Pasquer, Arnaud, Baraket, Oussama, Poncet, Gilles, Vaudoyer, Delphine, Jourdan Enfer, Peggy, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Godiris Petit, Gaelle, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Hannoun, Laurent, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, Valleur, Patrice, Markar, Sheraz R., Gronnier, Caroline, Duhamel, Alain, Behal, Hélène, Théreaux, Jérémie, Gagnière, Johan, Brigand, Cécile, Meunier, Bernard, Collet, Denis, and Mariette, Christophe

Published
2017
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18. Incidence and Risk Factors Related to Symptomatic Venous Thromboembolic Events After Esophagectomy for Cancer

Author

Dhahri, Abdennahceur, Lignier, Delphine, Cossé, Cyril, Regimbeau, Jean-Marc, Luc, Guillaume, Collet, Denis, Cabau, Magalie, Jougon, Jacques, Badic, Bogdan, Lozach, Patrick, Bail, Jean Pierre, Cappeliez, Serge, El Nakadi, Issam, Lebreton, Gil, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Stan-Iuga, Bogdan, Coueffé, Xaviéra, Contival, Nicolas, Pappalardo, Eric, Msika, Simon, Hec, Flora, Vanderbeken, Marguerite, Tessier, Williams, Briez, Nicolas, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Bigourdan, Jean-Marc, Mezoughi, Salim, Ducerf, Christian, Baulieux, Jacques, Mabrut, Jean-Yves, Pasquer, Arnaud, Baraket, Oussama, Poncet, Gilles, Adam, Mustapha, Vaudoyer, Delphine, Enfer, Peggy Jourdan, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean-Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Petit, Gaelle Godiris, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Vaillant, Jean-Christophe, Hannoun, Laurent, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, Valleur, Patrice, Lefevre, Jérémie, Chafai, Najim, Balladur, Pierre, Lefrançois, Magalie, Parc, Yann, Paye, François, Tiret, Emmanuel, Nedelcu, Marius, Laface, Letizia, Perniceni, Thierry, Gayet, Brice, Turner, Kathleen, Meunier, Bernard, Filipello, Alexandre, Porcheron, Jack, Tiffet, Olivier, Kamlet, Noémie, Chemaly, Rodrigue, Klipfel, Amandine, Pessaux, Patrick, Brigand, Cecile, Rohr, Serge, Chalret du Rieu, Mael, Carrère, Nicolas, Da Re, Chiara, Dumont, Frédéric, Goéré, Diane, Elias, Dominique, Bertrand, Claude, Mantziari, Styliani, Gronnier, Caroline, Gagnière, Johan, Théreaux, Jérémie, Demartines, Nicolas, Schäfer, Markus, and Mariette, Christophe

Published
2016
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19. Role of neoadjuvant treatment in clinical T2N0M0 oesophageal cancer: results from a retrospective multi-center European study

Author

Dhahri, Abdennahceur, Lignier, Delphine, Cossé, Cyril, Regimbeau, Jean-Marc, Collet, Denis, Cabau, Magalie, Jougon, Jacques, Badic, Bogdan, Lozach, Patrick, Bail, Jean Pierre, Cappeliez, Serge, Nakadi, Issam El, Lebreton, Gil, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Stan-Iuga, Bogdan, Contival, Nicolas, Pappalardo, Eric, Msika, Simon, Mantziari, Styliani, Demartines, Nicolas, Hec, Flora, Vanderbeken, Marguerite, Tessier, Williams, Briez, Nicolas, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Bigourdan, Jean Marc, Mezoughi, Salim, Ducerf, Christian, Baulieux, Jacques, Mabrut, Jean-Yves, Baraket, Oussama, Poncet, Gilles, Adham, Mustapha, Vaudoyer, Delphine, Enfer, Peggy Jourdan, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean-Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Petit, Gaelle Godiris, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Vaillant, Jean-Christophe, Hannoun, Laurent, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, Valleur, Patrice, Chafai, Najim, Balladur, Pierre, Lefrançois, Magalie, Parc, Yann, Paye, François, Tiret, Emmanuel, Nedelcu, Marius, Laface, Letizia, Perniceni, Thierry, Gayet, Brice, Meunier, Bernard, Filipello, Alexandre, Porcheron, Jack, Tiffet, Olivier, Kamlet, Noémie, Chemaly, Rodrigue, Klipfel, Amandine, Pessaux, Patrick, Brigand, Cecile, Rohr, Serge, Carrère, Nicolas, Da Re, Chiara, Dumont, Frédéric, Goéré, Diane, Elias, Dominique, Bertrand, Claude, Markar, Sheraz R., Gronnier, Caroline, Pasquer, Arnaud, Duhamel, Alain, Beal, Hélène, Théreaux, Jérémie, Gagnière, Johan, Brigand, Cécile, and Mariette, Christophe

Published
2016
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21. Chapter 18: Epilogue

Author

Stanbury, Myra, Henderson, Kandy-Jane, Derrien, Bernard, Bigourdan, Nicolas, and Le Touze, Evelyne

Published
2015

24. Self-Expanding Covered Metallic Stent as a Bridge to Surgery in Esophageal Cancer: Impact on Oncologic Outcomes

Author

Dhahri, Abdennahceur, Lignier, Delphine, Cossé, Cyril, Regimbeau, Jean-Marc, Luc, Guillaume, Cabau, Magalie, Jougon, Jacques, Lozach, Patrick, Thereaux, Jérémie, Badic, Bogdan, Cappeliez, Serge, El Nakadi, Issam, Lebreton, Gil, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Stan-Iuga, Bogdan, Contival, Nicolas, Pappalardo, Eric, Msika, Simon, Mantziari, Styliani, Hec, Flora, Vanderbeken, Marguerite, Tessier, Williams, Briez, Nicolas, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Mezoughi, Salim, Ducerf, Christian, Baulieux, Jacques, Bigourdan, Jean-Marc, Pasquer, Arnaud, Baraket, Oussama, Poncet, Gilles, Adam, Mustapha, Vaudoyer, Delphine, Jourdan Enfer, Peggy, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean-Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Godiris Petit, Gaelle, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Vaillant, Jean-Christophe, Hannoun, Laurent, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, Valleur, Patrice, Chafai, Najim, Balladur, Pierre, Lefrançois, Magalie, Parc, Yann, Paye, François, Tiret, Emmanuel, Nedelcu, Marius, Laface, Letizia, Perniceni, Thierry, Gayet, Brice, Turner, Kathleen, Filipello, Alexandre, Porcheron, Jack, Tiffet, Olivier, Kamlet, Noémie, Chemaly, Rodrigue, Klipfel, Amandine, Pessaux, Patrick, Brigand, Cecile, Rohr, Serge, du Rieu, Mael Chalret, Da Re, Chiara, Dumont, Frédéric, Goéré, Diane, Elias, Dominique, Bertrand, Claude, Mariette, Christophe, Gronnier, Caroline, Duhamel, Alain, Mabrut, Jean-Yves, Bail, Jean-Pierre, Carrere, Nicolas, Lefevre, Jérémie H., Meunier, Bernard, Collet, Denis, and Piessen, Guillaume

Published
2015
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26. Discrepancy Between Clinical and Pathologic Nodal Status of Esophageal Cancer and Impact on Prognosis and Therapeutic Strategy

Author

Markar, Sheraz R., Gronnier, Caroline, Pasquer, Arnaud, Duhamel, Alain, Behal, Hélène, Théreaux, Jérémie, Gagnière, Johan, Lebreton, Gil, Brigand, Cécile, Renaud, Florence, Piessen, Guillaume, Meunier, Bernard, Collet, Denis, Mariette, Christophe, Luc, Guillaume, Cabau, Magalie, Jougon, Jacques, Badic, Bogdan, Lozach, Patrick, Nakadi, Issam El, Cappeliez, Serge, Lebreton, Gil, Lubrano, Jean, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Iuga, Bogdan Stan, Contival, Nicolas, Pappalardo, Eric, Mantziari, Styliani, Demartines, Nicolas, Hec, Flora, Vanderbeken, Marguerite, Degisors, Sébastien, Marin, Hélène, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Bigourdan, Jean-Marc, Mezoughi, Salim, Mabrut, Jean-Yves, Ducerf, Christian, Baraket, Oussama, Poncet, Gilles, Vaudoyer, Delphine, Enfer, Peggy Jourdan, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Petit, Gaelle Godiris, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, and on Behalf of the FREGAT Working Group—FRENCH—AFC

Published
2017
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32. Detection potential of the KM3NeT detector for high-energy neutrinos from the Fermi bubbles

Author

Adrián-Martínez, S., Ageron, M., Aguilar, J.A., Aharonian, F., Aiello, S., Albert, A., Alexandri, M., Ameli, F., Anassontzis, E.G., Anghinolfi, M., Anton, G., Anvar, S., Ardid, M., Assis Jesus, A., Aubert, J.-J., Bakker, R., Ball, A.E., Barbarino, G., Barbarito, E., Barbato, F., Baret, B., de Bel, M., Belias, A., Bellou, N., Berbee, E., Berkien, A., Bersani, A., Bertin, V., Beurthey, S., Biagi, S., Bigongiari, C., Bigourdan, B., Billault, M., de Boer, R., Boer Rookhuizen, H., Bonori, M., Borghini, M., Bou-Cabo, M., Bouhadef, B., Bourlis, G., Bouwhuis, M., Bradbury, S., Brown, A., Bruni, F., Brunner, J., Brunoldi, M., Busto, J., Cacopardo, G., Caillat, L., Calvo Díaz-Aldagalán, D., Calzas, A., Canals, M., Capone, A., Carr, J., Castorina, E., Cecchini, S., Ceres, A., Cereseto, R., Chaleil, Th., Chateau, F., Chiarusi, T., Choqueuse, D., Christopoulou, P.E., Chronis, G., Ciaffoni, O., Circella, M., Cocimano, R., Cohen, F., Colijn, F., Coniglione, R., Cordelli, M., Cosquer, A., Costa, M., Coyle, P., Craig, J., Creusot, A., Curtil, C., D’Amico, A., Damy, G., De Asmundis, R., De Bonis, G., Decock, G., Decowski, P., Delagnes, E., De Rosa, G., Distefano, C., Donzaud, C., Dornic, D., Dorosti-Hasankiadeh, Q., Drogou, J., Drouhin, D., Druillole, F., Drury, L., Durand, D., Durand, G.A., Eberl, T., Emanuele, U., Enzenhöfer, A., Ernenwein, J.-P., Escoffier, S., Espinosa, V., Etiope, G., Favali, P., Felea, D., Ferri, M., Ferry, S., Flaminio, V., Folger, F., Fotiou, A., Fritsch, U., Gajanana, D., Garaguso, R., Gasparini, G.P., Gasparoni, F., Gautard, V., Gensolen, F., Geyer, K., Giacomelli, G., Gialas, I., Giordano, V., Giraud, J., Gizani, N., Gleixner, A., Gojak, C., Gómez-González, J.P., Graf, K., Grasso, D., Grimaldi, A., Groenewegen, R., Guédé, Z., Guillard, G., Guilloux, F., Habel, R., Hallewell, G., van Haren, H., van Heerwaarden, J., Heijboer, A., Heine, E., Hernández-Rey, J.J., Herold, B., Hillebrand, T., van de Hoek, M., Hogenbirk, J., Hößl, J., Hsu, C.C., Imbesi, M., Jamieson, A., Jansweijer, P., de Jong, M., Jouvenot, F., Kadler, M., Kalantar-Nayestanaki, N., Kalekin, O., Kappes, A., Karolak, M., Katz, U.F., Kavatsyuk, O., Keller, P., Kiskiras, Y., Klein, R., Kok, H., Kontoyiannis, H., Kooijman, P., Koopstra, J., Kopper, C., Korporaal, A., Koske, P., Kouchner, A., Koutsoukos, S., Kreykenbohm, I., Kulikovskiy, V., Laan, M., La Fratta, C., Lagier, P., Lahmann, R., Lamare, P., Larosa, G., Lattuada, D., Leisos, A., Lenis, D., Leonora, E., Le Provost, H., Lim, G., Llorens, C.D., Lloret, J., Löhner, H., Lo Presti, D., Lotrus, P., Louis, F., Lucarelli, F., Lykousis, V., Malyshev, D., Mangano, S., Marcoulaki, E.C., Margiotta, A., Marinaro, G., Marinelli, A., Mariş, O., Markopoulos, E., Markou, C., Martínez-Mora, J.A., Martini, A., Marvaldi, J., Masullo, R., Maurin, G., Migliozzi, P., Migneco, E., Minutoli, S., Miraglia, A., Mollo, C.M., Mongelli, M., Monmarthe, E., Morganti, M., Mos, S., Motz, H., Moudden, Y., Mul, G., Musico, P., Musumeci, M., Naumann, Ch., Neff, M., Nicolaou, C., Orlando, A., Palioselitis, D., Papageorgiou, K., Papaikonomou, A., Papaleo, R., Papazoglou, I.A., Păvălaş, G.E., Peek, H.Z., Perkin, J., Piattelli, P., Popa, V., Pradier, T., Presani, E., Priede, I.G., Psallidas, A., Rabouille, C., Racca, C., Radu, A., Randazzo, N., Rapidis, P.A., Razis, P., Real, D., Reed, C., Reito, S., Resvanis, L.K., Riccobene, G., Richter, R., Roensch, K., Rolin, J., Rose, J., Roux, J., Rovelli, A., Russo, A., Russo, G.V., Salesa, F., Samtleben, D., Sapienza, P., Schmelling, J.-W., Schmid, J., Schnabel, J., Schroeder, K., Schuller, J.-P., Schussler, F., Sciliberto, D., Sedita, M., Seitz, T., Shanidze, R., Simeone, F., Siotis, I., Sipala, V., Sollima, C., Sparnocchia, S., Spies, A., Spurio, M., Staller, T., Stavrakakis, S., Stavropoulos, G., Steijger, J., Stolarczyk, Th., Stransky, D., Taiuti, M., Taylor, A., Thompson, L., Timmer, P., Tonoiu, D., Toscano, S., Touramanis, C., Trasatti, L., Traverso, P., Trovato, A., Tsirigotis, A., Tzamarias, S., Tzamariudaki, E., Urbano, F., Vallage, B., Van Elewyck, V., Vannoni, G., Vecchi, M., Vernin, P., Viola, S., Vivolo, D., Wagner, S., Werneke, P., White, R.J., Wijnker, G., Wilms, J., de Wolf, E., Yepes, H., Zhukov, V., Zonca, E., Zornoza, J.D., and Zúñiga, J.

Published
2013
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41. Microstructural Gray Matter Integrity Deteriorates After an Ischemic Stroke and Is Associated with Processing Speed

Author

Sagnier, Sharmila, primary, Catheline, Gwenaëlle, additional, Dilharreguy, Bixente, additional, Linck, Pierre-Antoine, additional, Coupé, Pierrick, additional, Munsch, Fanny, additional, Bigourdan, Antoine, additional, Poli, Mathilde, additional, Debruxelles, Sabrina, additional, Renou, Pauline, additional, Olindo, Stéphane, additional, Rouanet, François, additional, Dousset, Vincent, additional, Tourdias, Thomas, additional, and Sibon, Igor, additional

Published
2022
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43. Multicentre study of neoadjuvant chemotherapy for stage I and II oesophageal cancer

Author

Bekkar, S., Gronnier, C., Renaud, F., Duhamel, A., Pasquer, A., Théreaux, J., Gagnière, J., Meunier, B., Collet, D., Mariette, C., Dhahri, A., Lignier, D., Cossé, C., Regimbeau, J.-M., Luc, G., Cabau, M., Jougon, J., Badic, B., Lozach, P., Bail, J. P., Cappeliez, S., El Nakadi, I., Lebreton, G., Alves, A., Flamein, R., Pezet, D., Pipitone, F., Stan-Iuga, B., Contival, N., Pappalardo, E., Coueffe, X., Msika, S., Mantziari, S., Demartines, N., Hec, F., Vanderbeken, M., Tessier, W., Briez, N., Fredon, F., Gainant, A., Mathonnet, M., Bigourdan, J. M., Mezoughi, S., Ducerf, C., Baulieux, J., Mabrut, J.-Y., Baraket, O., Poncet, G., Adam, M., Vaudoyer, D., Enfer, P. Jourdan, Villeneuve, L., Glehen, O., Coste, T., Fabre, J.-M., Marchal, F., Frisoni, R., Ayav, A., Brunaud, L., Bresler, L., Cohen, C., Aze, O., Venissac, N., Pop, D., Mouroux, J., Donici, I., Prudhomme, M., Felli, E., Lisunfui, S., Seman, M., Petit, G. Godiris, Karoui, M., Tresallet, C., Ménégaux, F., Vaillant, J.-C., Hannoun, L., Malgras, B., Lantuas, D., Pautrat, K., Pocard, M., Valleur, P., Lefevre, J. H., Chafai, N., Balladur, P., Lefrançois, M., Parc, Y., Paye, F., Tiret, E., Nedelcu, M., Laface, L., Perniceni, T., Gayet, B., Turner, K., Filipello, A., Porcheron, J., Tiffet, O., Kamlet, N., Chemaly, R., Klipfel, A., Pessaux, P., Brigand, C., Rohr, S., Carrère, N., Da Re, C., Dumont, F., Goéré, D., Elias, D., and Bertrand, C.

Published
2016
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46. Normal-Appearing White Matter Deteriorates over the Year After an Ischemic Stroke and Is Associated with Global Cognition

Author

Sharmila Sagnier, Gwenaëlle Catheline, Bixente Dilharreguy, Pierre-Antoine Linck, Pierrick Coupé, Fanny Munsch, Antoine Bigourdan, Mathilde Poli, Sabrina Debruxelles, Pauline Renou, Stéphane Olindo, François Rouanet, Vincent Dousset, Thomas Tourdias, Igor Sibon, Coupé, Pierrick, Institut de Neurosciences cognitives et intégratives d'Aquitaine (INCIA), Université Bordeaux Segalen - Bordeaux 2-Université Sciences et Technologies - Bordeaux 1 (UB)-SFR Bordeaux Neurosciences-Centre National de la Recherche Scientifique (CNRS), CHU Bordeaux [Bordeaux], Laboratoire Bordelais de Recherche en Informatique (LaBRI), Université de Bordeaux (UB)-École Nationale Supérieure d'Électronique, Informatique et Radiocommunications de Bordeaux (ENSEIRB)-Centre National de la Recherche Scientifique (CNRS), Patch-based processing for medical and natural images (PICTURA), Université de Bordeaux (UB)-École Nationale Supérieure d'Électronique, Informatique et Radiocommunications de Bordeaux (ENSEIRB)-Centre National de la Recherche Scientifique (CNRS)-Université de Bordeaux (UB)-École Nationale Supérieure d'Électronique, Informatique et Radiocommunications de Bordeaux (ENSEIRB)-Centre National de la Recherche Scientifique (CNRS), Beth Israel Deaconess Medical Center [Boston] (BIDMC), Harvard Medical School [Boston] (HMS), Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale (U1215 Inserm - UB), and Université de Bordeaux (UB)-Institut François Magendie-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
Aged, 80 and over, Male, General Neuroscience, [INFO.INFO-IM] Computer Science [cs]/Medical Imaging, Leukoaraiosis, Middle Aged, Prognosis, White Matter, Stroke, Cognition, Diffusion Tensor Imaging, Longitudinal, [INFO.INFO-IM]Computer Science [cs]/Medical Imaging, Humans, Female, Neurology (clinical), Longitudinal Studies, Cardiology and Cardiovascular Medicine, Aged, Ischemic Stroke
Abstract

International audience; Normal-appearing white matter (NAWM) is a hub of plasticity, but data relating to its influence on post-ischemic stroke (IS) outcome remain scarce. The aim of this study was to evaluate the relationship between NAWM integrity and cognitive outcome after an IS. A longitudinal study was conducted including supra-tentorial IS patients. A 3-Tesla brain MRI was performed at baseline and 1 year, allowing the analyses of mean fractional anisotropy (FA) and mean diffusivity (MD) in NAWM masks, along with the volume of white matter hyperintensities (WMH) and IS. A Montreal Cognitive Assessment (MoCA), an Isaacs set test, and a Zazzo's cancellation task were performed at baseline, 3 months and 1 year. Mixed models were built, followed by Tract-based Spatial Statistics (TBSS) analyses. Ninety-five patients were included in the analyses (38% women, median age 69 ± 20). FA significantly decreased, and MD significantly increased between baseline and 1 year, while cognitive scores improved. Patients who decreased their NAWM FA more over the year had a slower cognitive improvement on MoCA (β = - 0.11, p = 0.05). The TBSS analyses showed that patients who presented the highest decrease of FA in various tracts of white matter less improved their MoCA performances, regardless of WMH and IS volumes, demographic confounders, and clinical severity. NAWM integrity deteriorates over the year after an IS, and is associated with a cognitive recovery slowdown. The diffusion changes recorded here in patients starting with an early preserved white matter structure could have long term impact on cognition.

Published
2021
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48. Chronic Cortical Cerebral Microinfarcts Slow Down Cognitive Recovery After Acute Ischemic Stroke

Author

Vincent Dousset, Gwénaëlle Catheline, Fanny Munsch, Mathilde Poli, Thomas Tourdias, Antoine Bigourdan, François Rouanet, Stéphane Olindo, Gosuke Okubo, Sabrina Debruxelles, Igor Sibon, Pauline Renou, and Sharmila Sagnier

Subjects
medicine.medical_specialty, 030204 cardiovascular system & hematology, 03 medical and health sciences, Cognition, 0302 clinical medicine, Atrophy, Alzheimer Disease, Internal medicine, Neuroplasticity, medicine, Humans, Dementia, Vascular dementia, Stroke, Aged, Aged, 80 and over, Cerebral Cortex, Advanced and Specialized Nursing, medicine.diagnostic_test, business.industry, Dementia, Vascular, Montreal Cognitive Assessment, Magnetic resonance imaging, Cerebral Infarction, Middle Aged, Mental Status and Dementia Tests, medicine.disease, Magnetic Resonance Imaging, Chronic Disease, Hypertension, Cardiology, Neurology (clinical), Alzheimer's disease, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery
Abstract

Background and Purpose— Cortical cerebral microinfarcts (CMIs) have been associated with vascular dementia and Alzheimer disease. The aim of the present study was to evaluate the role of cortical CMI detected on 3T magnetic resonance imaging, on the evolution of cognition during the year following an acute ischemic stroke. Methods— We conducted a prospective and monocentric study, including patients diagnosed for a supratentorial ischemic stroke with a National Institutes of Health Stroke Scale score ≥1, without prestroke dementia or neurological disability. Cortical CMIs were assessed on a brain 3T magnetic resonance imaging realized at baseline, as well as markers of small vessel disease, stroke characteristics, and hippocampal atrophy. Cognitive assessment was performed at 3 time points (baseline, 3 months, and 1 year) using the Montreal Cognitive Assessment, the Isaacs set test, and the Zazzo’s cancellation task. Generalized linear mixed models were performed to evaluate the relationships between the number of cortical CMI and changes in cognitive scores over 1 year. Results— Among 199 patients (65±13 years old, 68% men), 88 (44%) had at least one cortical CMI. Hypertension was the main predictor of a higher cortical CMI load (B=0.58, P =0.005). The number of cortical CMI was associated with an increase time at the Zazzo’s cancellation task over 1 year (B=3.84, P =0.01), regardless of the other magnetic resonance imaging markers, stroke severity, and demographic factors. Conclusions— Cortical CMIs are additional magnetic resonance imaging markers of poorer processing speed after ischemic stroke. These results indicate that a high load of cortical CMI in patients with stroke can be considered as a cerebral frailty condition which counteracts to the recovery process, suggesting a reduced brain plasticity among these patients.

Published
2019
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49. The short- and long-term outcomes of pancreaticoduodenectomy for cancer in child a patients are acceptable: A patient-control study from the Surgical French Association report for pancreatic surgery

Author

Regimbeau, Jean-Marc, Rebibo, Lionel, Dokmak, Safi, Boher, Jean-Marie, Sauvanet, Alain, Chopin-Laly, Xavier, Adham, Mustapha, Lesurtel, Mickaël, Bigourdan, Jean-Marc, Truant, Stéphanie, Pruvot, François-René, Ortega-Deballon, Pablo, Paye, François, Bachellier, Philippe, and Delpero, Jean-Robert

Published
2015
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