92 results on '"Bignon, Jerome"'
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2. Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors
3. Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues
4. Synthesis and evaluation of a novel class of ethacrynic acid derivatives containing triazoles as potent anticancer agents
5. Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation
6. Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency
7. N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents
8. Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A
9. A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation
10. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors
11. Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents
12. Discovery of azaisoerianin derivatives as potential antitumors agents
13. Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs
14. Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: Synthesis, cytotoxicity and antitubulin activity
15. Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4
16. Variation in gene expression profiles of human monocytic U937 cells exposed to various fluxes of nitric oxide
17. Synthesis and biological evaluation of ethacrynic acid derivatives bearing sulfonamides as potent anti-cancer agents
18. DMSO–PdI 2 as a powerful oxidizing couple of alkynes into benzils: one-pot synthesis of nitrogen-containing five- or six-membered heterocycles
19. Pro-apoptotic carboxamide analogues of natural fislatifolic acid targeting Mcl-1 and Bcl-2
20. AcSDKP: a new potential marker of malignancy of the thyroid gland
21. Pyrrolo-imidazo[1,2-a]pyridine Scaffolds through a Sequential Coupling of N-Tosylhydrazones with Imidazopyridines and Reductive Cadogan Annulation, Synthetic Scope, and Application
22. Overexpression of the natural tetrapeptide acetyl-N-ser-asp-lys-pro derived from thymosin β4 in neoplastic diseases
23. Asymmetric Total Synthesis and Biological Evaluation of Proapoptotic Natural Myrcene-Derived Cyclohexenyl Chalcones
24. The tetrapeptide AcSDKP, an inhibitor of primitive hematopoietic cell proliferation, induces angiogenesis in vitro and in vivo
25. 3rd-Generation Analogs of Meiogynin A, New Cytotoxic Multiple Inhibitors of Anti-apoptotic Proteins of Bcl-2 Family
26. Csp2–Csp2and Csp2–N Bond Formation in a One-Pot Reaction between N-Tosylhydrazones and Bromonitrobenzenes: An Unexpected Cyclization to Substituted Indole Derivatives
27. Csp2–Csp2 and Csp2–N Bond Formation in a One-Pot Reaction between N-Tosylhydrazones and Bromonitrobenzenes: An Unexpected Cyclization to Substituted Indole Derivatives
28. Développement et évaluation biologique d'inhibiteurs des protéines anti-apoptotiques de la famille Bcl-2
29. Synthesis and biological evaluation of C-13′ substituted 7′-homo-anhydrovinblastine derivatives
30. ChemInform Abstract: Palladium‐Catalyzed One‐Pot Synthesis of 5‐(1‐Arylvinyl)‐1H‐benzimidazoles: Overcoming the Limitation of Acetamide Partners.
31. ChemInform Abstract: Transition-Metal-Free Synthesis of Polysubstituted Cyclopropane Derivatives from N-Tosylhydrazones and Their Cytotoxic Activities.
32. A general synthesis of arylindoles and (1-arylvinyl)carbazoles via a one-pot reaction from N-tosylhydrazones and 2-nitro-haloarenes and their potential application to colon cancer
33. ChemInform Abstract: Palladium‐Catalyzed One‐Pot Reaction of Hydrazones, Dihaloarenes, and Organoboron Reagents: Synthesis and Cytotoxic Activity of 1,1‐Diarylethylene Derivatives.
34. Overexpression of the natural tetrapeptide acetyl-N-ser-asp-lys-pro derived from thymosin beta4 in neoplastic diseases
35. ChemInform Abstract: Rapid Synthesis of 4‐Arylchromenes from ortho‐Substituted Alkynols: A Versatile Access to Restricted Isocombretastatin A‐4 Analogues as Antitumor Agents.
36. ChemInform Abstract: Tandem One-Pot Palladium-Catalyzed Coupling of Hydrazones, Haloindoles, and Amines: Synthesis of Amino-N-vinylindoles and Their Effect on Human Colon Carcinoma Cells.
37. ChemInform Abstract: An Efficient Coupling of N-Tosylhydrazones with 2-Halopyridines: Synthesis of 2-α-Styrylpyridines Endowed with Antitumor Activity.
38. Synthesis and antitumor activity of benzils related to combretastatin A-4
39. ChemInform Abstract: Regioselective Hydrostannation of Diarylalkynes Directed by a Labile ortho Bromine Atom: An Easy Access to Stereodefined Triarylolefins, Hybrids of Combretastatin A-4 and Isocombretastatin A-4.
40. Elevated plasma levels of the angiogenic tetrapeptide acetyl-ser-asp-lys-pro are found in some patients with hematologic malignancies
41. ChemInform Abstract: Synthesis and Antitumor Activity of Benzils Related to Combretastatin A‐4.
42. ChemInform Abstract: DMSO—PdI2 as a Powerful Oxidizing Couple of Alkynes into Benzils: One‐Pot Synthesis of Nitrogen‐Containing Five‐ or Six‐Membered Heterocycles.
43. Src Kinase Activity Is Regulated by the SHP-1 Protein-tyrosine Phosphatase
44. Identification of PTP1C Mutation as the Genetic Defect in Motheaten and Viable Motheaten Mice: A Step toward Defining the Roles of Protein Tyrosine Phosphatases in the Regulation of Hemopoietic Cell Differentiation and Function
45. Marine Sponges from Indian Ocean: A Highly Promising Source for the Discovery of Novel Bioactive Compounds to Fight against Ageing and Age-Related Diseases
46. Synthesis and Biological Evaluation of a New Series of Highly Functionalized 7 '-homo-Anhydrovinblastine Derivatives
47. Overexpression of the angiogenic tetrapeptide AcSDKP in human malignant tumors
48. ChemInform Abstract: Regioselective Hydrostannation of Diarylalkynes Directed by a Labile ortho Bromine Atom: An Easy Access to Stereodefined Triarylolefins, Hybrids of Combretastatin A-4 and Isocombretastatin A-4.
49. ChemInform Abstract: DMSO-PdI2 as a Powerful Oxidizing Couple of Alkynes into Benzils: One-Pot Synthesis of Nitrogen-Containing Five- or Six-Membered Heterocycles.
50. ChemInform Abstract: DMSO—PdI2as a Powerful Oxidizing Couple of Alkynes into Benzils: One‐Pot Synthesis of Nitrogen‐Containing Five‐ or Six‐Membered Heterocycles.
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