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6 results on '"Biffaro, N."'

2. P057 Persistent hypertransaminasemia in an obese child with asymptomatic Wilson disease and familiarity for parkinsonism and cardiomyopathy: a case report

Author

Rocco, M.C., primary, Lettieri, M., additional, Biffaro, N., additional, Colantuono, R., additional, Paglia, P., additional, Siano, M.A., additional, Satta, S., additional, Lepori, M.B., additional, Loudianos, G., additional, Mandato, C., additional, Pacifico, R., additional, Nazzaro, L., additional, De Anseris, A.G.E., additional, Di Nuzzi, A., additional, and Vajro, P., additional

Published
2018
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3. P056 Metabolic syndrome and/or NAFLD: not always obesity related!

Author

Lettieri, M., primary, Di Michele, L., additional, Delli Bovi, A.P., additional, Amico, M., additional, Smaldone, C., additional, Paglia, P., additional, Colantuono, R., additional, Biffaro, N., additional, Siano, M.A., additional, Rocco, M.C., additional, Nazzaro, L., additional, and Vajro, P., additional

Published
2018
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6. Atypically Protracted Course of Liver Involvement in Kawasaki Disease. Case Report and Literature Review.

Author

Paglia P, Nazzaro L, De Anseris AGE, Lettieri M, Colantuono R, Rocco MC, Siano MA, Biffaro N, and Vajro P

Abstract

Hypertransaminasemia in patients with Kawasaki disease (KD) is reported to be transient. Here, we describe a child with an atypically protracted course of liver tests abnormalities and review the inherent literature. The patient was hospitalized at age 7-months for isolated hypertransaminasemia detected during a classical KD diagnosed 3 months before, and persistent since then. KD clinical evolution had been favorable, with rapid response to acetylsalicylic acid and intravenous immunoglobulins. Liver enzymes however remained persistently elevated with a fluctuating pattern (ALT > AST levels; peak of AST 186 IU/L and ALT 240 IU/L). During follow-up, the main causes of liver dysfunction had to be excluded through appropriate and extensive laboratory investigations. Transaminases values become steadily normal only 7 months after the acute presentation of KD. Conclusions: Our report shows that an atypically protracted courses of KD-related hypertransaminasemia above the previously reported temporal limits should be taken into account during the stepwise diagnostic approach to the patient's liver dysfunction. Insidious acetylsalycilic acid-hepatotoxicity warrants consideration in the differential diagnosis.

Published
2021
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