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226 results on '"Bicout, D"'

1. Rupture of a Biomembrane under Dynamic Surface Tension

Author

Bicout, D. J. and Kats, E. I.

Subjects
Condensed Matter - Soft Condensed Matter
Abstract

How long a fluid membrane vesicle stressed with a steady ramp of micropipette last before rupture? Or conversely, how high the surface tension should be to rupture a membrane? To answer these challenging questions we have developed a theoretical framework that allows description and reproduction of Dynamic Tension Spectroscopy (DTS) observations. The kinetics of the membrane rupture under ramps of surface tension is described as a combination of initial pore formation followed by Brownian process of the pore radius crossing the time-dependent energy barrier. We present the formalism and derive (formal) analytical expression of the survival probability describing the fate of the membrane under DTS conditions. Using numerical simulations for the membrane prepared in an initial state with a given distribution of times for pore nucleation, we have studied the membrane lifetime (or inverse of rupture rate) and distribution of membrane surface tension at rupture as a function of membrane characteristics like pore nucleation rate, the energy barrier to failure and tension loading rate. It is found that simulations reproduce main features of the experimental data, particularly, the pore nucleation and pore size diffusion controlled limits of membrane rupture dynamics. This approach can also be applied to processes of permeation and pore opening in membranes (electroporation, membrane disruption by antimicrobial peptides, vesicle fusion)., Comment: 11 pages, 9 figures

Published
2011
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2. Title Stabilization of Membrane Pores by Packing

Author

Bicout, D. J., Schmid, F., and Kats, E.

Subjects
Condensed Matter - Soft Condensed Matter, Condensed Matter - Statistical Mechanics
Abstract

We present a model for pore stabilization in membranes without surface tension. Whereas an isolated pore is always unstable (since it either shrinks tending to re-seal or grows without bound til to membrane disintegration), it is shown that excluded volume interactions in a system of many pores can stabilize individual pores of a given size in a certain range of model parameters. For such a multipore membrane system, the distribution of pore size and associated pore lifetime are calculated within the mean field approximation. We predict that, above certain temperature when the effective line tension becomes negative, the membrane exhibits a dynamic sieve-like porous structure., Comment: 4 pages, 4 figures

Published
2006
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3. Vibrational Enhancement of the Effective Donor - Acceptor Coupling

Author

Lazrek, M., Bicout, D. J., Jaziri, S., and Kats, E.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Disordered Systems and Neural Networks
Abstract

The paper deals with a simple three sites model for charge transfer phenomena in an one-dimensional donor (D) - bridge (B) - acceptor (A) system coupled with vibrational dynamics of the B site. It is found that in a certain range of parameters the vibrational coupling leads to an enhancement of the effective donor - acceptor electronic coupling as a result of the formation of the polaron on the B site. This enhancement of the charge transfer efficiency is maximum at the resonance, where the effective energy of the fluctuating B site coincides with the donor (acceptor) energy., Comment: 5 pages, 3 figures

Published
2005
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4. Bridge-mediated Donor-Acceptor Effective Coupling: Exact theoretical description

Author

Bicout, D. J., Varchon, F., and Kats, E.

Subjects
Condensed Matter - Soft Condensed Matter, Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

An exact expression of the bridge-mediated donor-acceptor effective coupling, is derived. For systems represented by a tight-binding Hamiltonian with nearest-neighbor interactions, we show that the effective coupling, is equal to the product over all square of nearest-neighbor couplings divided by an appropriate product of level spacing of eigen energies of the Hamiltonian. Results of this calculation are compared to those obtained by perturbative approaches and some drawbacks of the latter are pointed out., Comment: 4 pages, submitted to Europhysics Letters

Published
2005

5. Bubble Relaxation Dynamics in Double-Stranded DNA

Author

Bicout, D. J. and Kats, E.

Subjects
Condensed Matter - Soft Condensed Matter, Condensed Matter - Statistical Mechanics
Abstract

The paper deals with the two-state (opening-closing of base pairs) model used to describe the fluctuation dynamics of a single bubble formation. We present an exact solution for the discrete and finite size version of the model that includes end effects and derive analytic expressions of the correlation function, survival probability and lifetimes for the bubble relaxation dynamics. It is shown that the continuous and semi-infinite limit of the model becomes a good approximation to exact result when a^N << 1, where N is bubble size and a, the ratio of opening to closing rates of base pairs, is the control parameter of DNA melting., Comment: 4 pages, 2 figures, submitted to Physical Review E as a rapid communication

Published
2004
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6. Simulation of a semiflexible polymer in a narrow cylindrical pore

Author

Bicout, D. J. and Burkhardt, T. W.

Subjects
Condensed Matter - Statistical Mechanics
Abstract

The probability that a randomly accelerated particle in two dimensions has not yet left a simply connected domain ${\cal A}$ after a time $t$ decays as $e^{-E_0t}$ for long times. The same quantity $E_0$ also determines the confinement free energy per unit length $\Delta f=k_BT\thinspace E_0$ of a semiflexible polymer in a narrow cylindrical pore with cross section ${\cal A}$. From simulations of a randomly accelerated particle we estimate the universal amplitude of $\Delta f$ for both circular and rectangular cross sections., Comment: 10 pages, 2 eps figures

Published
2001
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7. Influence of the Environment Fluctuations on Incoherent Neutron Scattering Functions

Author

Bicout, D. J.

Subjects
Condensed Matter - Soft Condensed Matter
Abstract

In extending the conventional dynamic models, we consider a simple model to account for the environment fluctuations of particle atoms in a protein system and derive the elastic incoherent structure factor (EISF) and the incoherent scattering correlation function C(Q,t) for both the jump dynamics between sites with fluctuating site interspacing and for the diffusion inside a fluctuating sphere. We find that the EISF of the system (or the normalized elastic intensity) is equal to that in the absence of fluctuations averaged over the distribution of site interspacing or sphere radius a. The scattering correlation function is $C(Q,t)=\sum_{n}<{\rm e}^{-\lambda_n(a) t}> \psi(t)$, where the average is taken over the Q-dependent effective distribution of relaxation rates \lambda_n(a) and \psi(t) is the correlation function of the length a. When \psi(t)=1, the relaxation of C(Q,t) is exponential for the jump dynamics between sites (since \lambda_n(a) is independent of a) while it is nonexponential for diffusion inside a sphere., Comment: 7 pages, 7 eps figures

Published
2001
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8. Irreversibble Bimolecular Reactions of Langevin Particles

Author

Bicout, D. J., Berezhkovskii, A. M., and Szabo, Attila

Subjects
Condensed Matter - Statistical Mechanics, Condensed Matter - Soft Condensed Matter
Abstract

The reaction A+B --> B is studied when the reactants diffuse in phase space, i.e. their dynamics is described by the Langevin equation. The steady-state rate constants are calculated for both the target (static A and mobile B's) and trapping (mobile A and static B's) problems when the reaction is assumed to occur at the first contact. For Brownian dynamics (i.e., ordinary diffusion), the rate constant for both problems is a monotonically decreasing function of the friction coefficient $\gamma$. For Langevin dynamics, however, we find that the steady-state rate constant exhibits a turnover behavior as a function of $\gamma$ for the trapping problem but not for the target problem. This turnover is different from the familiar Kramers' turnover of the rate constant for escape from a deep potential well because the reaction considered here is an activationless process., Comment: 29 pages including 7 figures

Published
2000
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16. Risk of survival, establishment and spread of Batrachochytrium salamandrivorans (Bsal) in the EU

Author

More, S., Miranda, M.A., Bicout, D., Bøtner, A., Butterworth, A., Calistri, P., Depner, K., Edwards, S., Garin‐Bastuji, B., Good, M., Michel, V., Raj, M., Nielsen, S.S., Sihvonen, L., Martel, A., Spoolder, H., Stegeman, J.A., Thulke, Hans-Hermann, Velarde, A., Willeberg, P., Winckler, C., Baláž, V., Murray, K., Fabris, C., Munoz‐Gajardo, I., Gogin, A., Verdonck, F., Gortázar Schmidt, C., More, S., Miranda, M.A., Bicout, D., Bøtner, A., Butterworth, A., Calistri, P., Depner, K., Edwards, S., Garin‐Bastuji, B., Good, M., Michel, V., Raj, M., Nielsen, S.S., Sihvonen, L., Martel, A., Spoolder, H., Stegeman, J.A., Thulke, Hans-Hermann, Velarde, A., Willeberg, P., Winckler, C., Baláž, V., Murray, K., Fabris, C., Munoz‐Gajardo, I., Gogin, A., Verdonck, F., and Gortázar Schmidt, C.

Abstract

Batrachochytrium salamandrivorans (Bsal) is an emerging fungal pathogen of salamanders. Despite limited surveillance, Bsal was detected in kept salamanders populations in Belgium, Germany, Spain, the Netherlands and the United Kingdom, and in wild populations in some regions of Belgium, Germany and the Netherlands. According to niche modelling, at least part of the distribution range of every salamander species in Europe overlaps with the climate conditions predicted to be suitable for Bsal. Passive surveillance is considered the most suitable approach for detection of Bsal emergence in wild populations. Demonstration of Bsal absence is considered feasible only in closed populations of kept susceptible species. In the wild, Bsal can spread by both active (e.g. salamanders, anurans) and passive (e.g. birds, water) carriers; it is most likely maintained/spread in infected areas by contacts of salamanders or by interactions with anurans, whereas human activities most likely cause Bsal entry into new areas and populations. In kept amphibians, Bsal contamination via live silent carriers (wild birds and anurans) is considered extremely unlikely. The risk‐mitigation measures that were considered the most feasible and effective: (i) for ensuring safer international or intra‐EU trade of live salamanders, are: ban or restrictions on salamander imports, hygiene procedures and good practice manuals; (ii) for protecting kept salamanders from Bsal, are: identification and treatment of positive collections; (iii) for on‐site protection of wild salamanders, are: preventing translocation of wild amphibians and release/return to the wild of kept/temporarily housed wild salamanders, and setting up contact points/emergency teams for passive surveillance. Combining several risk‐mitigation measures improve the overall effectiveness. It is recommended to: introduce a harmonised protocol for Bsal detection throughout the EU; improve data acquisition on salamander abundance and dis

Published
2018

17. Étude longitudinale du métabolome de Pseudomonas aeruginosa au cours des infections pulmonaires chroniques dans la mucoviscidose

Author

Moyne, O, Cournoyer, B, Castelli, F, Fenaille, F, Lamourette, P, Junot, C, Léger, Christophe, Bicout, D., Maurin, M, Toussaint, B, Le Gouëllec, A, Thérapeutique Recombinante Expérimentale (TIMC-IMAG-TheREx), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre Hospitalier Universitaire [Grenoble] (CHU), and ZOPPIS, Catherine

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2017

23. Target and trapping problems: From the ballistic to the diffusive regime.

Author

Berezhkovskii, A. M., Bicout, D. J., and Weiss, G.H.

Subjects
*CHEMICAL reactions, *SOLVENTS, *ION traps, *SOLUTION (Chemistry)
Abstract

Reports on the calculations of the survival probability and rate coefficient of chemical reactions in solvents by applying methodology based on the analysis in a model for target and trapping problems. Solution of the target problem providing a mean-field approximation to the solution of the trapping problem not only in the diffusive regime.

Published
1999
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24. Description of the Traditional Poultry Industry in West Africa: The Case of Senegal and Togo

Author

Kone, P, Bicout, D J, and Akakpo, A J

Subjects
Traditional poultry, Chain actors, Marketing chain, Biosecurity
Abstract

The traditional poultry industry covers more than 70-80% of the poultry production in West Africa countries. Surveys conducted in 2010-2011 on the market and producers present in the surrounding rural weekly markets have allowed to characterize the actors in the sector, to identify their activities estimate the average number of incoming and outgoing poultry in these markets, and to assess biosafety level in these markets in both West African countries including Senegal and Togo. The survey of the poultry sector in rural communities can be described as a more or less complex circuit, where the major actors in the sector are: i) producers who are farmers living in villages or rural communities; (ii) the primary and secondary collectors who buy poultry and sell them in rural markets (weekly) or collection markets (daily); and iii) wholesalers who gather poultry from the collectors for delivery them to larger markets particularly in urban markets and/or outside the country. Trade flows of live poultry between actors vary according to countries. Cleaning in the farms appeared moderately frequent (3-4 per week) with the use of disinfectants in 15-25% of cases, biosafety in weekly markets, acceptable (control at the arrival and weekly cage cleaning) and the mortality rate (30-40% among adults and 60-70% in chicks) remains high. In our study, the return of unsold chickens in the farms could be a practical risk of propagation and maintenance of infectious disease in this sector.Keywords : Traditional poultry, Chain actors, Marketing chain, Biosecurity.

Published
2014

26. Description of the Traditional Poultry Industry in West Africa: The Case of Senegal and Togo

Author

P., Koné, Bicout, D., A. J., Akakpo, Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), and ZOPPIS, Catherine

Subjects
[SDV] Life Sciences [q-bio], Chain actors, Biosecurity, [SDV]Life Sciences [q-bio], Marketing chain, health care economics and organizations, Traditional poultry
Abstract

International audience; The traditional poultry industry covers more than 70-80% of the poultry production in West Africa countries. Surveys conducted in 2010-2011 on the market and producers present in the surrounding rural weekly markets have allowed to characterize the actors in the sector, to identify their activities estimate the average number of incoming and outgoing poultry in these markets, and to assess biosafety level in these markets in both West African countries including Senegal and Togo. The survey of the poultry sector in rural communities can be described as a more or less complex circuit, where the major actors in the sector are: i) producers who are farmers living in villages or rural communities; (ii) the primary and secondary collectors who buy poultry and sell them in rural markets (weekly) or collection markets (daily); and iii) wholesalers who gather poultry from the collectors for delivery them to larger markets particularly in urban markets and/or outside the country. Trade flows of live poultry between actors vary according to countries. Cleaning in the farms appeared moderately frequent (3-4 per week) with the use of disinfectants in 15-25% of cases, biosafety in weekly markets, acceptable (control at the arrival and weekly cage cleaning) and the mortality rate (30-40% among adults and 60-70% in chicks) remains high. In our study, the return of unsold chickens in the farms could be a practical risk of propagation and maintenance of infectious disease in this sector.

Published
2014

27. Impacts of climate on occurrences of suitable periods for mosquitoes, vector of disease, in the Camargue and Dombes areas, France

Author

Bicout, D. J., Eyraud-Griffet, A., Pradel, J., Karine Chalvet-Monfray, Sabatier, P., UPE, European Union Reference Laboratory for equine diseases (EURL), Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Unité de Recherche d'Épidémiologie Animale (UR EpiA), Institut National de la Recherche Agronomique (INRA), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], mosquitoe, impact, France, dombes, climate, vector, ComputingMilieux_MISCELLANEOUS, camargue
Abstract

International audience

Published
2010

28. Effect of the climate change on the meteorological driven risk of Dengue occurrence

Author

Karine Chalvet-Monfray, Sriprom, -., Bicout, D. J., Unité de Recherche d'Épidémiologie Animale (UR EpiA), Institut National de la Recherche Agronomique (INRA), UPE, European Union Reference Laboratory for equine diseases (EURL), Sakon Nakhon Rajabhat University, Partenaires INRAE, Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], meteorological driven risk, impact, occurrence, climate, dengue, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2010

29. Wild birds and West Nile virus in the Western Palearctic: the example of the Camargue area

Author

Jourdain, Elsa, Sabatier, P., Zeller, H., Schuffenecker, I., Korimbocus, J., Murri, Severine, Reynard, S., Toussaint, Y., Kayser, Y., Leblond, Agnès, Bicout, D., Gauthier-Clerc, M., Centre de Recherche de la Tour du Valat (CRTV), Ecole Nationale Vétérinaire de Lyon (ENVL), Institut Pasteur [Paris], Unité de Recherche d'Épidémiologie Animale (UR EpiA), Institut National de la Recherche Agronomique (INRA), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], wild bird, [SDV]Life Sciences [q-bio], western paleartic, west nile virus, ComputingMilieux_MISCELLANEOUS, camargue
Abstract

International audience

Published
2007

32. Birds and West Nile virus in a Mediterranean wetland, the Camargue

Author

Jourdain, Elsa, Zeller, H, Sabatier, P, Kayser, Y, Grège, O, Murri, S, Toussaint, Y, Reynard, S, Bicout, D, Leblond, A, Gauthier-Clerc, M, Martel, Anne-Sophie, Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), École nationale vétérinaire - Alfort (ENVA), Centre de Recherche de la Tour du Valat (CRTV), Institut Pasteur de Lyon, Réseau International des Instituts Pasteur (RIIP), Unité biomathématiques et épidémiologie, Ecole Nationale Vétérinaire de Lyon (ENVL), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Institut Pasteur [Paris], and Ecole Nationale Vétérinaire

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2006

33. Urgent request on avian influenza.

Author

More, S, Bicout, D, Bøtner, A, Butterworth, A, Calistri, P, Depner, K, Edwards, S, Garin‐Bastuji, B, Good, M, Gortázar Schmidt, C, Michel, V, Miranda, MA, Saxmose Nielsen, S, Raj, M, Sihvonen, L, Spoolder, H, Thulke, HH, Velarde, A, Willeberg, P, and Winckler, C

Subjects
*AVIAN influenza, *COMMUNICABLE diseases in animals, *BIRDS, *BIOSECURITY, *POULTRY farms
Abstract

HPAI H5N8 is currently causing an epizootic in Europe, infecting many poultry holdings as well as captive and wild bird species in more than ten countries. Given the clear clinical manifestation, passive surveillance is considered the most effective means of detecting infected wild and domestic birds. Testing samples from new species and non-previously reported areas is key to determine the geographic spread of HPAIV H5N8 2016 in wild birds. Testing limited numbers of dead wild birds in previously-reported areas is useful when it is relevant to know whether the virus is still present in the area or not, e.g. before restrictive measures in poultry are to be lifted. To prevent introduction of HPAIV from wild birds into poultry, strict biosecurity implemented and maintained by the poultry farmers is the most important measure. Providing holding-specific biosecurity guidance is strongly recommended as it is expected to have a high impact on the achieved biosecurity level of the holding. This is preferably done during peace time to increase preparedness for future outbreaks. The location and size of control and in particular monitoring areas for poultry associated with positive wild bird findings are best based on knowledge of the wider habitat and flight distance of the affected wild bird species. It is recommended to increase awareness among poultry farmers in these established areas in order to enhance passive surveillance and to implement enhanced biosecurity measures including poultry confinement. There is no scientific evidence suggesting a different effectiveness of the protection measures on the introduction into poultry holdings and subsequent spread of HPAIV when applied to H5N8, H5N1 or other notifiable HPAI viruses. [ABSTRACT FROM AUTHOR]

Published
2017
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34. A study on free-ranging wild birds to better understand their role in the circulation of West Nile virus in Camargue, southern France

Author

Jourdain, Elsa, Gauthier-Clerc, M, Bicout, D, Zeller, H, Murri, S, Sabatier, P, Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS), Centre de recherche de la Tour du Valat, Ecologie comportementale (EC), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Recherche Agronomique (INRA)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université Paris-Sud - Paris 11 (UP11)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université de Rennes (UR)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS), Unité biomathématiques et épidémiologie, Ecole Nationale Vétérinaire de Lyon (ENVL), Institut Pasteur [Paris] (IP), Institut Pasteur de Lyon, Réseau International des Instituts Pasteur (RIIP), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Recherche Agronomique (INRA)-Université Montpellier 2 - Sciences et Techniques (UM2)-Université Paris-Sud - Paris 11 (UP11)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université Claude Bernard Lyon 1 (UCBL), Institut Pasteur [Paris], and Martel, Anne-Sophie

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2005

35. Searching for a link between the L-BMAA neurotoxin and amyotrophic lateral sclerosis: a study protocol of the French BMAALS programme

Author

Delzor, A., primary, Couratier, P., additional, Boumediene, F., additional, Nicol, M., additional, Druet-Cabanac, M., additional, Paraf, F., additional, Mejean, A., additional, Ploux, O., additional, Leleu, J.-P., additional, Brient, L., additional, Lengronne, M., additional, Pichon, V., additional, Combes, A., additional, El Abdellaoui, S., additional, Bonneterre, V., additional, Lagrange, E., additional, Besson, G., additional, Bicout, D. J., additional, Boutonnat, J., additional, Camu, W., additional, Pageot, N., additional, Juntas-Morales, R., additional, Rigau, V., additional, Masseret, E., additional, Abadie, E., additional, Preux, P.-M., additional, and Marin, B., additional

Published
2014
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37. Lyme disease in Alsace: geographical distribution of tick bites and erythema migrans vs environmental factors

Author

Jourdain, Elsa, Bicout, D, Balducci, F, Deshayes, F, Schmitt, M, Artois, M, Sabatier, P, Environnement et Prédiction de la Santé des Populations (TIMC-IMAG-EPSP), Techniques de l'Ingénierie Médicale et de la Complexité - Informatique, Mathématiques et Applications, Grenoble - UMR 5525 (TIMC-IMAG), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Unité biomathématiques et épidémiologie, Ecole Nationale Vétérinaire de Lyon (ENVL), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institut Cochin (UMR_S567 / UMR 8104), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), and Martel, Anne-Sophie

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2003

38. Analysis of seroprevalence among horses in an endemic area of West Nile Disease, Camargue, France

Author

Bicout, D., Leblond, Agnès, Heng, M.A., Durand, B., Zientara, Stephan, Durand, J.P., Sabatier, P., Unité biomathématiques et épidémiologie, Ecole Nationale Vétérinaire de Lyon (ENVL), Agence Française de Sécurité Sanitaire des Aliments (AFSSA), Virologie, École nationale vétérinaire d'Alfort (ENVA)-Institut National de la Recherche Agronomique (INRA)-Agence Française de Sécurité Sanitaire des Aliments (AFSSA), and Service de Santé des Armées

Subjects
WEST NILE VIRUS, MARKOV PROCESS, [SDV]Life Sciences [q-bio], SEROPREVALENCE, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2003

39. Isolation of Yellow Fever Virus from Nulliparous Haemagogus (Haemagogus) janthinomys in Eastern Amazonia

Author

Mondet, B, Vasconcelos, Pedro Fernando da Costa, Rosa, Am?lia Paes de Andrade Travassos da, Rosa, Elizabeth Salb? Travassos da, Rodrigues, Sueli Guerreiro, Rosa, Jorge Fernando Soares Travassos da, and Bicout, D. J

Subjects
Febre Amarela / imunologia, Transmiss?o Vertical de Doen?a Infecciosa, Amaz?nia Oriental (BR), Febre Amarela / epidemiologia, Alouatta / sangue, V?rus da Febre Amarela / isolamento & purifica??o, Vetores de Doen?as
Abstract

Institut de Recherche pour le D?veloppment, Paris, France. Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil. Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil. Minist?rio da Sa?de - Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil. Minist?rio da Sa?de. Funda??o Nacional de Sa?de. Instituto Evandro Chagas. Bel?m, PA, Brasil. Institut National de Recherche Agronomique. Ecole Nationale V?t?rinaire. Marcy l'?toile, France. In 1998, an epizootic of yellow fever (YF) killed many howler monkeys

Published
2002

40. Outbreaks of highly pathogenic avian influenza in Europe : the risks associated with wild birds

Author

Artois, M., Bicout, D., Doctrinal, D., Fouchier, R., Gavier-Widen, D., Globig, A., Hagemeijer, W., Mundkur, T., Munster, V., Olsen, Björn, Artois, M., Bicout, D., Doctrinal, D., Fouchier, R., Gavier-Widen, D., Globig, A., Hagemeijer, W., Mundkur, T., Munster, V., and Olsen, Björn

Abstract

The infection of wild birds by highly pathogenic strains of avian influenza (Al) virus was virtually unknown--apart from one instance of the disease appearing in common terns in South Africa in 1961--before the Asian strain of highly pathogenic AI virus (AIV), H5N1, began to expand across the world. Outbreaks of clinical disease in Eurasia have resulted in visible mortality among populations of free-ranging wild birds in a multitude of species. The circulation pattern of influenza viruses in natural ecosystems results from a selection pressure towards strains which are indirectly transmitted by droppings from water birds and contaminated fomites, and which exhibit low pathogenicity. Some of these viruses, of the subtypes H5 or H7, can mutate into highly pathogenic strains after being introduced into domestic poultry farms. The maintenance of highly pathogenic AIV (HPAIV) H5N1 in several parts of the world exposes wild birds to infected poultry, resulting in long-distance virus transmission. There is great concern that these wild birds may, in turn, propagate these HPAIV or introduce them into domestic birds. Rigorous disease control and biosecurity measures to protect poultry farms are the only solution presently available to mitigate such a risk.

Published
2009

42. Long range correlations in DNA: scaling properties and charge transfer efficiency

Author

Roche, S., Bicout, D., Maciá Barber, Enrique Alfonso, Kats, E., Roche, S., Bicout, D., Maciá Barber, Enrique Alfonso, and Kats, E.

Abstract

©2003 The American Physical Society., We address the relation between long-range correlations and charge transfer efficiency in aperiodic artificial or genomic DNA sequences. Coherent charge transfer through the highest occupied molecular orbital states of the guanine nucleotide is studied using the transmission approach, and the focus is on how the sequence-dependent backscattering profile can be inferred from correlations between base pairs., Depto. de Física de Materiales, Fac. de Ciencias Físicas, TRUE, pub

Published
2003

49. Surveillance of occupational disease

Author

Bonneterre, V., primary, Bicout, D. J., additional, Larabi, L., additional, Maitre, A., additional, Tubert-Bitter, P., additional, de Gaudemaris, R., additional, McNamee, R., additional, Chen, Y., additional, Hussey, L., additional, Agius, R., additional, Concha, M., additional, Labbe, J., additional, Giaconi, J., additional, Valenty, M., additional, Homere, J., additional, Pubert, M., additional, Touranchet, A., additional, Ha, C., additional, and Imbernon, E., additional

Published
2007
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