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4. Comparison of ultrasound- versus fluoroscopy-guidEd femorAl access In tranS-catheter aortic valve replacement In the Era of contempoRary devices: The EASIER registry

Author

Bianchini, Emiliano, Morello, Alberto, Bellamoli, Michele, Romagnoli, Enrico, Aurigemma, Cristina, Tagliaferri, Marco, Montonati, Carolina, Dumonteil, Nicolas, Cimmino, Michele, Villa, Emmanuel, Corcione, Nicola, Bettari, Luca, Messina, Antonio, Stanzione, Alessio, Troise, Giovanni, Mor, Donata, Maggi, Antonio, Bellosta, Raffaello, Pegorer, Matteo Alberto, Zoccai, Giuseppe Biondi, Ielasi, Alfonso, Burzotta, Francesco, Trani, Carlo, Maffeo, Diego, Tchétché, Didier, Buono, Andrea, and Giordano, Arturo

Published
2024
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5. Impact of thrombus aspiration on left ventricular remodeling and function in patients with ST-segment elevation myocardial infarction: A meta-analysis of randomized controlled trials

Author

Bianchini, Emiliano, Lombardi, Marco, Buonpane, Angela, Ricchiuto, Alfredo, Maino, Alessandro, Laborante, Renzo, Anastasia, Gianluca, D'Amario, Domenico, Aurigemma, Cristina, Romagnoli, Enrico, Leone, Antonio Maria, D'Ascenzo, Fabrizio, Trani, Carlo, Crea, Filippo, Porto, Italo, Burzotta, Francesco, and Vergallo, Rocco

Published
2024
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9. Fractional flow reserve or optical coherence tomography for angiographically intermediate coronary stenoses: 5-year outcomes in the FORZA trial

Author

Burzotta, Francesco, primary, Zito, Andrea, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, Bianchini, Francesco, additional, Bianchini, Emiliano, additional, Paraggio, Lazzaro, additional, Ierardi, Carolina, additional, Crea, Filippo, additional, Leone, Antonio Maria, additional, and Trani, Carlo, additional

Published
2024
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10. Anatomical Annulus Predictors of New Permanent Pacemaker Implantation Risk after Balloon-expandable Trans-catheter Aortic Valve Implantation

Author

Bianchini, Francesco, primary, Bianchini, Emiliano, additional, Romagnoli, Enrico, additional, Aurigemma, Cristina, additional, Zito, Andrea, additional, Busco, Marco, additional, Nesta, Marialisa, additional, Bruno, Piergiorgio, additional, Laezza, Domenico, additional, Giambusso, Nicole, additional, Natale, Luigi, additional, Pelargonio, Gemma, additional, Burzotta, Francesco, additional, and Trani, Carlo, additional

Published
2024
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12. Impact of coronary microvascular dysfunction in heart failure with preserved ejection fraction: a meta‐analysis.

Author

D'Amario, Domenico, Laborante, Renzo, Bianchini, Emiliano, Ciliberti, Giuseppe, Paglianiti, Donato Antonio, Galli, Mattia, Restivo, Attilio, Stolfo, Davide, Vergallo, Rocco, Rosano, Giuseppe M.C., Crea, Filippo, Lam, Carolyn S.P., Lund, Lars H., Metra, Marco, Patti, Giuseppe, and Savarese, Gianluigi

Subjects
PROGNOSIS, MICROCIRCULATION disorders, ATRIAL fibrillation, VENTRICULAR ejection fraction, ODDS ratio, HEART failure
Abstract

Aims: Several mechanisms have been identified in the aetiopathogenesis of heart failure with preserved ejection fraction (HFpEF). Among these, coronary microvascular dysfunction (CMD) may play a key pathophysiological role. We performed a systematic review and meta‐analysis to investigate the prevalence, echocardiographic correlates, and prognostic implications of CMD in patients with HFpEF. Methods and results: A systematic search for articles up to 1 May 2023 was performed. The primary aim was to assess the prevalence of CMD. Secondary aims were to compare key echocardiographic parameters (E/e′ ratio, left atrial volume index [LAVi], and left ventricular mass index [LVMi]), clinical outcomes [death and hospitalization for heart failure (HF)], and prevalence of atrial fibrillation (AF) between patients with and without CMD. Meta‐regressions according to baseline patient characteristics and study features were performed to explore potential heterogeneity sources. We identified 14 observational studies, enrolling 1138 patients with HFpEF. The overall prevalence of CMD was 58%. Compared with patients without CMD, patients with HFpEF and CMD had larger LAVi [mean difference (MD) 3.85 confidence interval (CI) 1.19–6.5, P < 0.01)], higher E/e′ ratio (MD 2.76 CI 1.54–3.97; P < 0.01), higher prevalence of AF (odds ratio 1.61 CI 1.04–2.48, P = 0.03) and higher risk of death or hospitalization for HF [hazard ratio 3.19, CI 1.04–9.57, P = 0.04]. Conclusions: CMD is present in little more than half of the patients with HFpEF and is associated with echocardiographic evidence of more severe diastolic dysfunction and a higher prevalence of AF, doubling the risk of death or HF hospitalization. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Pre-stenting residual thrombotic volume assessed by dual quantitative coronary angiography predicts microvascular obstruction in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Author

VERGALLO, Rocco, primary, LOMBARDI, Marco, additional, BESIS, Giorgos, additional, MIGLIARO, Stefano, additional, RICCHIUTO, Alfredo, additional, MAINO, Alessandro, additional, BUONPANE, Angela, additional, BIANCHINI, Emiliano, additional, ANNIBALI, Gianmarco, additional, GALLI, Mattia, additional, D’AMARIO, Domenico, additional, MONTONE, Rocco A., additional, LEONE, Antonio M., additional, AURIGEMMA, Cristina, additional, ROMAGNOLI, Enrico, additional, BUFFON, Antonino, additional, HAMILTON-CRAIG, Christian, additional, BURZOTTA, Francesco, additional, PORTO, Italo, additional, TRANI, Carlo, additional, and CREA, Filippo, additional

Published
2023
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16. 515 ADENOSINE AS ADJUNCTIVE THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME: WHEN LESS IS MORE. AN UPDATED META-ANALYSIS OF 26 RANDOMIZED CONTROLLED TRIALS.

Author

Laborante, Renzo, primary, Bianchini, Emiliano, additional, Ciliberti, Giuseppe, additional, Restivo, Attilio, additional, Galli, Mattia, additional, Zito, Andrea, additional, Princi, Giuseppe, additional, Antonio Montone, Rocco, additional, Vergallo, Rocco, additional, Romagnoli, Enrico, additional, Aurigemma, Cristina, additional, Maria Leone, Antonio, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, Crea, Filippo, additional, and D´amario, Domenico, additional

Published
2022
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17. 1150 SEX-BASED DIFFERENCES IN CORONARY PLAQUE PHENOTYPE AND HEALING AT OPTICAL COHERENCE TOMOGRAPHY (OCT) ANALYSIS

Author

Buonpane, Angela, primary, Ricchiuto, Alfredo, additional, Lombardi, Marco, additional, Maino, Alessandro, additional, Bianchini, Emiliano, additional, Busco, Marco, additional, D´amario, Domenico, additional, Leone, Antonio Maria, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, Crea, Filippo, additional, and Vergallo, Rocco, additional

Published
2022
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19. 654 ECHOCARDIOGRAPHIC PARAMETERS AND CLINICAL OUTCOMES IN HEART FAILURE WITH PRESERVED EJECTION FRACTION AND CORONARY MICROVASCULAR DYSFUNCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS

Author

Laborante, Renzo, primary, Bianchini, Emiliano, additional, Restivo, Attilio, additional, Ciliberti, Giuseppe, additional, Paglianiti, Donato Antonio, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, Crea, Filippo, additional, and D´amario, Domenico, additional

Published
2022
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20. 417 CLINICAL IMPACT OF HEALED CORONARY PLAQUES: AN OPTICAL COHERENCE TOMOGRAPHY STUDY

Author

Ricchiuto, Alfredo, primary, Zella, Samuela, additional, Lombardi, Marco, additional, Buonpane, Angela, additional, Bianchini, Emiliano, additional, Maino, Alessandro, additional, Busco, Marco, additional, D´amario, Domenico, additional, Leone, Antonio Maria, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, Crea, Filippo, additional, and Vergallo, Rocco, additional

Published
2022
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21. Adenosine as adjunctive therapy in acute coronary syndrome: a meta-analysis of randomized controlled trials

Author

Laborante, Renzo, primary, Bianchini, Emiliano, additional, Restivo, Attilio, additional, Ciliberti, Giuseppe, additional, Galli, Mattia, additional, Vergallo, Rocco, additional, Rodolico, Daniele, additional, Zito, Andrea, additional, Princi, Giuseppe, additional, Leone, Antonio Maria, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, Montone, Rocco Antonio, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, Crea, Filippo, additional, and D'Amario, Domenico, additional

Published
2022
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23. 103 Coronary plaque healing and diabetes: insights from optical coherence tomography imaging

Author

Vergallo, Rocco, primary, Lombardi, Marco, additional, Betti, Matteo, additional, Ricchiuto, Alfredo, additional, Maino, Alessandro, additional, Buonpane, Angela, additional, Bianchini, Emiliano, additional, Galli, Mattia, additional, D’Amario, Domenico, additional, Montone, Rocco Antonio, additional, Leone, Antonio Maria, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, Buffon, Antonino, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, and Crea, Filippo, additional

Published
2021
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24. 734 Have I lost my large rupture cavity? The fingerprint of atherosclerotic plaque healing detected by serial optical coherence tomography imaging

Author

Ricchiuto, Alfredo, primary, Vergallo, Rocco, additional, Lombardi, Marco, additional, Maino, Alessandro, additional, Bianchini, Emiliano, additional, Buonpane, Angela, additional, D’Ascenzo, Domenico, additional, Romagnoli, Enrico, additional, Leone, Antonio Maria, additional, Aurigemma, Cristina, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, and Crea, Filippo, additional

Published
2021
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25. 736 Hazy spots: through the eye of optical coherence tomography

Author

Bianchini, Emiliano, primary, Vergallo, Rocco, additional, Buonpane, Angela, additional, Lombardi, Marco, additional, Ricchiuto, Alfredo, additional, Trani, Carlo, additional, Burzotta, Francesco, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, and Crea, Filippo, additional

Published
2021
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26. 698 Acute coronary syndrome in neoatherosclerosis with major stent malapposition and OCT-guided PCI

Author

Buonpane, Angela, primary, Vergallo, Rocco, additional, Bianchini, Emiliano, additional, Lombardi, Marco, additional, Maino, Alessandro, additional, Ricchiuto, Alfredo, additional, Leone, Antonio Maria, additional, Aurigemma, Cristina, additional, Romagnoli, Enrico, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, and Crea, Filippo, additional

Published
2021
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27. 499 What light through yonder window breaks? Benefits of optical coherence tomography (OCT) in a case of spontaneous coronary artery dissection

Author

Maino, Alessandro, primary, Vergallo, Rocco, additional, Ricchiuto, Alfredo, additional, Lombardi, Marco, additional, Buonpane, Angela, additional, Bianchini, Emiliano, additional, Romagnoli, Enrico, additional, Aurigemma, Cristina, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, and Crea, Filippo, additional

Published
2021
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28. 713 Culprit plaque morphology and healing capacity in patients with and without preinfarction angina: an optical coherence tomography imaging study

Author

Vergallo, Rocco, primary, Ricchiuto, Alfredo, additional, Ridolfi, Francesco, additional, Buonpane, Angela, additional, Bianchini, Emiliano, additional, Maino, Alessandro, additional, Lombardi, Marco, additional, D’A mario, Domenico, additional, Montone, Rocco, additional, Romagnoli, Enrico, additional, Leone, Antonio Maria, additional, Buffon, Antonino, additional, Aurigemma, Cristina, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, and Crea, Filippo, additional

Published
2021
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29. Abstract 12824: Culprit Plaque Morphology and Healing Capacity in Patients With and Without Pre-Infarction Angina: An Optical Coherence Tomography Imaging Study

Author

Vergallo, Rocco, primary, Ricchiuto, Alfredo, additional, Francesco, Ridolfi, additional, Lombardi, Marco, additional, Maino, Alessandro, additional, Buonpane, Angela, additional, Bianchini, Emiliano, additional, Galli, Mattia, additional, Domenico, D'Amario, additional, Montone, Rocco, additional, Leone, Antonio Maria, additional, aurigemma, cristina, additional, Romagnoli, Enrico, additional, Buffon, Antonino, additional, Burzotta, Francesco, additional, Trani, Carlo, additional, and crea, Filippo, additional

Published
2021
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30. Adenosine as adjunctive therapy in acute coronary syndrome: a meta-analysis of randomized controlled trials

Author

Laborante, Renzo, Bianchini, Emiliano, Restivo, Attilio, Ciliberti, Giuseppe, Galli, Mattia, Vergallo, Rocco, Rodolico, Daniele, Zito, Andrea, Princi, Giuseppe, Leone, Antonio Maria, Aurigemma, Cristina, Romagnoli, Enrico, Montone, Rocco Antonio, Burzotta, Francesco, Trani, Carlo, Crea, Filippo, and D'Amario, Domenico

Abstract

Graphical AbstractAdenosine enhances the risk of advanced atrioventricular blocks and ventricular arrhythmias in patients with long ischaemic time, without providing any clinical benefit.

Published
2023
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33. Femoral Large Bore Sheath Management: How to Prevent Vascular Complications From Vessel Puncture to Sheath Removal.

Author

Paraggio L, Bianchini F, Aurigemma C, Romagnoli E, Bianchini E, Zito A, Lunardi M, Trani C, and Burzotta F

Abstract

Transfemoral access is nowadays required for an increasing number of percutaneous procedures, such as structural heart interventions, mechanical circulatory support, and interventional electrophysiology/pacing. Despite technological advancements and improved techniques, these devices necessitate large-bore (≥12 French) arterial/venous sheaths, posing a significant risk of bleeding and vascular complications, whose occurrence has been related to an increase in morbidity and mortality. Therefore, optimizing large-bore vascular access management is crucial in endovascular interventions. Technical options, including optimized preprocedural planning and proper selection and utilization of vascular closure devices, have been developed to increase safety. This review explores the comprehensive management of large-bore accesses, from optimal vascular puncture to sheath removal. It also discusses strategies for managing closure device failure, with the goal of minimizing vascular complications.

Published
2024
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35. Adenosine as adjunctive therapy in acute coronary syndrome: a meta-analysis of randomized controlled trials.

Author

Laborante R, Bianchini E, Restivo A, Ciliberti G, Galli M, Vergallo R, Rodolico D, Zito A, Princi G, Leone AM, Aurigemma C, Romagnoli E, Montone RA, Burzotta F, Trani C, Crea F, and D'Amario D

Subjects
Humans, Adenosine adverse effects, Randomized Controlled Trials as Topic, Vasodilator Agents adverse effects, Acute Coronary Syndrome diagnosis, Acute Coronary Syndrome drug therapy, Atrioventricular Block chemically induced, Atrioventricular Block drug therapy, Heart Failure drug therapy, Myocardial Infarction drug therapy
Abstract

Aims: Adenosine has been tested in several randomized controlled trials (RCTs) to minimize the incidence of coronary microvascular obstruction (CMVO). The aim of this study was to pool all the RCTs comparing intracoronary or intravenous adenosine versus placebo in patients with acute coronary syndrome (ACS) undergoing myocardial revascularization., Methods and Results: PubMed and Scopus electronic databases were scanned for eligible studies up to 5th June 2022. A total of 26 RCTs with 5843 patients were included. Efficacy endpoints were major adverse cardiac events (MACE), all-cause death, non-fatal myocardial infarction, and heart failure. Atrioventricular blocks and ventricular fibrillation/sustained ventricular tachycardia (VF/SVT) were the safety endpoints. Myocardial blush grade, thrombolysis in myocardial infarction (TIMI) flow grade, left ventricular ejection fraction (LVEF), infarct size, and ST-segment resolution were also assessed. Adenosine administration was not associated with any clinical benefit in terms of MACE, all-cause death, non-fatal myocardial infarction, and heart failure. However, adenosine was associated with an increased rate of advanced atrioventricular blocks and of VF/SVT in studies with total mean ischaemic time >3 h, compared to placebo. Remarkably, among patients undergoing percutaneous coronary intervention, adenosine was associated with reduced myocardial blush grade 0-1 and TIMI flow grade 0-2, compared to placebo. Furthermore, adenosine did not show favourable effects on LVEF and infarct size., Conclusion: Adenosine infusion, as adjunctive therapy in ACS, was associated with an increased risk of advanced atrioventricular blocks and increased rates of adenosine-triggered ventricular arrhythmias in patients with long ischaemic time, without providing any clinical benefit compared to placebo., (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.)

Published
2023
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