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26 results on '"Bian, Haiyang"'

2. scMulan: A Multitask Generative Pre-Trained Language Model for Single-Cell Analysis

Author

Bian, Haiyang, Chen, Yixin, Dong, Xiaomin, Li, Chen, Hao, Minsheng, Chen, Sijie, Hu, Jinyi, Sun, Maosong, Wei, Lei, Zhang, Xuegong, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, van Leeuwen, Jan, Series Editor, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Kobsa, Alfred, Series Editor, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Nierstrasz, Oscar, Series Editor, Pandu Rangan, C., Editorial Board Member, Sudan, Madhu, Series Editor, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Vardi, Moshe Y, Series Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, and Ma, Jian, editor

Published
2024
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5. General-purpose pre-trained large cellular models for single-cell transcriptomics.

Author

Bian, Haiyang, Chen, Yixin, Luo, Erpai, Wu, Xinze, Hao, Minsheng, Wei, Lei, and Zhang, Xuegong

Subjects
*ARTIFICIAL neural networks, *LANGUAGE models, *FEEDFORWARD neural networks, *GENE regulatory networks, *TRANSFORMER models, *NATURAL language processing, *SYNTHETIC biology
Abstract

The article explores the use of large cellular models (LCMs) pre-trained on single-cell RNA-seq data with AI language models, showcasing their effectiveness in tasks such as cell type annotation and drug response prediction. These models, based on Transformer structures, are still in the early stages of research but hold promise for gene network inference, cell clustering, and multi-omics integration. The future of LCMs involves incorporating spatial transcriptomics and temporal data for improved biological insights and applications. The document references various research articles in biology, quantitative biology, and artificial intelligence, authored by researchers from diverse backgrounds, highlighting global collaboration in scientific research and the importance of open access and proper citation in academic work. [Extracted from the article]

Published
2024
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9. uniHEART: An Ensemble Atlas of Cardiac Cells Provides Multifaceted Portraits of the Human Heart

Author

Zhang, Xuegong, primary, Chen, Yixin, additional, Hua, Kui, additional, Xu, Shuhuan, additional, You, Renke, additional, Hao, Minsheng, additional, Li, Wenrui, additional, Wei, Lei, additional, Jia, Jinmeng, additional, Xi, Xi, additional, Chen, Sijie, additional, Bian, Haiyang, additional, Ye, Mingli, additional, Chen, Amin, additional, Geng, Yu, additional, Liu, Lianfeng, additional, Luo, Jiangying, additional, Fei, Jintao, additional, Lv, Hairong, additional, Zhang, Ping, additional, and Jiang, Rui, additional

Published
2023
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11. hECA: The cell-centric assembly of a cell atlas

Author

Chen, Sijie, primary, Luo, Yanting, additional, Gao, Haoxiang, additional, Li, Fanhong, additional, Chen, Yixin, additional, Li, Jiaqi, additional, You, Renke, additional, Hao, Minsheng, additional, Bian, Haiyang, additional, Xi, Xi, additional, Li, Wenrui, additional, Li, Weiyu, additional, Ye, Mingli, additional, Meng, Qiuchen, additional, Zou, Ziheng, additional, Li, Chen, additional, Li, Haochen, additional, Zhang, Yangyuan, additional, Cui, Yanfei, additional, Wei, Lei, additional, Chen, Fufeng, additional, Wang, Xiaowo, additional, Lv, Hairong, additional, Hua, Kui, additional, Jiang, Rui, additional, and Zhang, Xuegong, additional

Published
2022
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12. Male waist circumference in relation to semen quality and partner infertility treatment outcomes among couples undergoing infertility treatment with assisted reproductive technologies

Author

Universitat Rovira i Virgili, Bian, Haiyang; Minguez-Alarcon, Lidia; Salas-Huetos, Albert; Bauer, David; Williams, Paige L.; Souter, Irene; Attaman, Jill; Chavarro, Jorge E.;EARTH Study Team, Universitat Rovira i Virgili, and Bian, Haiyang; Minguez-Alarcon, Lidia; Salas-Huetos, Albert; Bauer, David; Williams, Paige L.; Souter, Irene; Attaman, Jill; Chavarro, Jorge E.;EARTH Study Team

Abstract

Background Male obesity has been related to poor semen quality and may also have a negative effect on assisted reproductive technologies (ART) outcomes. Whether male waist circumference (WC), as a measure of central obesity, impacts a couple's fertility independently of BMI is unclear. Objectives To examine the associations of male WC with semen quality and couples’ outcomes of infertility treatment with ART. Methods Couples presenting to the Massachusetts General Hospital Fertility Center were invited to participate in the study. Between 2009 and 2019, 269 males provided 671 semen samples and 176 couples underwent 317 ART cycles. Height, weight, and WC were measured on site. We analyzed the association of male WC with semen quality and pregnancy outcomes using cluster-weighted regression models to account for repeated observations while adjusting for potential confounders. Models were also stratified by male BMI (<25 kg/m2 compared with ?25 kg/m2). Results The median male age, WC, and BMI were 36.1 years, 96.0 cm, and 26.8 kg/m2, respectively. A 5-cm increase in WC was associated with a 6.3% (95% CI, 2.1–10.5%) lower sperm concentration after adjustment for potential confounders, including BMI. Male WC was also inversely related to the probability of achieving a live birth. For each 5-cm increase in male WC, the odds of a live birth per initiated cycle decreased by 9.0% (95% CI, 1.1%–16.4%) after accounting for several anthropometric and demographic characteristics of both partners. These associations were stronge

Published
2022

13. Detection and Subtyping of Hepatic Echinococcosis from Plain CT Images with Deep Learning: A Retrospective, Multicenter Study

Author

Wang, Zhan, primary, Bian, Haiyang, additional, Li, Jiaqi, additional, Xu, Jin, additional, Fan, Haining, additional, Wu, Xinze, additional, Cao, Yuntai, additional, Guo, Bin, additional, Xu, Xiaolei, additional, Wang, Haijiu, additional, Zhang, Lingqiang, additional, Zhou, Hu, additional, Fan, Jianfeng, additional, Ren, Youyou, additional, Geng, Yunping, additional, Feng, Xiaobin, additional, Wei, Lei, additional, and Zhang, Xuegong, additional

Published
2022
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14. hECA: the cell-centric assembly of a cell atlas

Author

Chen, Sijie, primary, Luo, Yanting, additional, Gao, Haoxiang, additional, Li, Fanhong, additional, Li, Jiaqi, additional, Chen, Yixin, additional, You, Renke, additional, Hao, Minsheng, additional, Bian, Haiyang, additional, Xi, Xi, additional, Li, Wenrui, additional, Li, Weiyu, additional, Ye, Mingli, additional, Meng, Qiuchen, additional, Zou, Ziheng, additional, Li, Chen, additional, Li, Haochen, additional, Zhang, Yangyuan, additional, Cui, Yanfei, additional, Wei, Lei, additional, Chen, Fufeng, additional, Wang, Xiaowo, additional, Lv, Hairong, additional, Hua, Kui, additional, Jiang, Rui, additional, and Zhang, Xuegong, additional

Published
2021
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19. Dietary inflammatory potential and risk of sarcopenia: data from national health and nutrition examination surveys

Author

Geng, Jiwen, primary, Deng, Linghui, additional, Qiu, Shi, additional, Bian, Haiyang, additional, Cai, Boyu, additional, Jin, Kun, additional, Zheng, Xiaonan, additional, Li, Jiakun, additional, Liao, Xinyang, additional, Li, Yupei, additional, Li, Jiameng, additional, Qin, Zheng, additional, Cao, Zhiwei, additional, Bao, Yige, additional, and Su, Baihai, additional

Published
2020
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23. Demographic variations and temporal trends in prenatal use of multiple micronutrient supplements in Beijing, 2013-2017.

Author

Bian, Haiyang, Tang, Youchi, Zhou, Yubo, Li, Hongtian, and Liu, Jianmeng

Subjects
*IRON supplements, *MATERNAL health, *PREGNANT women, *NULLIPARAS, *SECONDARY education, *METROPOLITAN areas, *PRENATAL care
Abstract

Objective: To provide updated information about demographic variations and temporal trends in the prenatal use of multiple micronutrient (MMN) supplements in the metropolitan areas of China.Design: Descriptive analysis of routine prenatal healthcare data between 2013 and 2017.Setting: Chaoyang District, Beijing, China.Participants: A total of 197 346 pregnant women who attended their first prenatal care visit and provided information about MMN supplementation during the periconceptional period.Results: Of these pregnant women, 60·6 % reported consuming prenatal MMN supplements. In multivariate-adjusted models, there were significant gradients of age, education and parity in prenatal MMN supplementation, with the highest likelihood of MMN use among the oldest, the most highly educated and nulliparous women (Pfor trend < 0·001). Compared with that among unemployed women, prenatal MMN supplementation was more common among the employed, especially those engaged in business (adjusted relative risks (95 % CI): 1·08 (1·06, 1·10)) and management (1·10 (1·08, 1·12)). The proportion of prenatal MMN supplementation was 57·0 % in 2013, which increased to 63·5 % in 2017 (Pfor trend < 0·001). The trends varied by age, education and parity (Pfor heterogeneity < 0·001), whereas no significant difference was observed in trends across subgroups of ethnicity or occupation. The greatest magnitude increase in MMN supplement use occurred in women of age < 25 years (annual percent change: 5·7 %), less than high school education (9·6 %), parity ≥ 2 (6·8 %) or unemployment (6·1 %).Conclusion: Approximately two-thirds of women consumed prenatal MMN supplements during the periconceptional period in the central area of Beijing and the proportion increased over time, indicating a need to evaluate the effectiveness and safety and to develop a guideline for relatively well-nourished women. [ABSTRACT FROM AUTHOR]

Published
2021
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