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1. Italian Guidelines in patch testing - Adapted from the European Society of Contact Dermatitis (ESCD)

Author

Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Stingeni, L., Bianchi, L., Hansel, K., Corazza, M., Gallo, R., Guarneri, F., Patruno, C., Rigano, L., Romita, P., Pigattoatt, P. D., Calzavara-Pintoton, P., Agostinelli, S., Albertazzi, D., Angelini, G., Angerosa, F., Arigliano, P. L., Assalve, D., Ayala, F., Bellonifortina, A., Berta, M., Biale, C., Biasini, I., Boccaletti, V., Bonamonte, D., Borghi, A., Brambilla, L., Bressan, M., Bruno, A., Caccavale, S., Calogiuri, G., Cannavò, S. P., Carugno, A., Cataldi, I., Chiarelli, G., Chiesa, A., Cirla, A. M., Cossutta, M., Cova, L. M., Cristaudo, A., Dalcan-Ton, M., Damiani, G., Danese, P., Desalvo, V., Fantini, C., Ferrucci, S. M., Flori, M. L., Fontana, E., Foti, C., Francalanci, S., Frasin, L. A., Gola, M., Gravante, M., Guastaferro, D., Ingordo, V., Lauriola, M. M., Leghissa, P., Lisi, P., Lombardi, P., Lorenzini, M., Magrini, L., Marone, G., Martina, E., Mascagni, P., Matteinichiari, M., Meligeni, L., Melino, M., Milanesi, N., Molinu, A. A., Monfrecola, G., Morelli, P., Motolese, A., Musumeci, M. L., Napolitano, M., Nasca, M. R., Paganini, P., Papini, M., Pasolini, G., Peroni, A., Peserico, A., Piras, V., Pugliese, A., Raponi, F., Raviolo, P. D., Rebora, A., Recchia, G. P., Riva, F., Rossi, M., Ruggieri, M., Saggiorato, F., Sartorelli, P., Schena, D., Schettino, A., Spano, G., Stinchi, C., Taddei, L., Tasin, L., Tramontana, M., Valsecchi, R. H., Vascellaro, A., Venturini, M., Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Stingeni, L., Bianchi, L., Hansel, K., Corazza, M., Gallo, R., Guarneri, F., Patruno, C., Rigano, L., Romita, P., Pigattoatt, P. D., Calzavara-Pintoton, P., Agostinelli, S., Albertazzi, D., Angelini, G., Angerosa, F., Arigliano, P. L., Assalve, D., Ayala, F., Bellonifortina, A., Berta, M., Biale, C., Biasini, I., Boccaletti, V., Bonamonte, D., Borghi, A., Brambilla, L., Bressan, M., Bruno, A., Caccavale, S., Calogiuri, G., Cannavò, S. P., Carugno, A., Cataldi, I., Chiarelli, G., Chiesa, A., Cirla, A. M., Cossutta, M., Cova, L. M., Cristaudo, A., Dalcan-Ton, M., Damiani, G., Danese, P., Desalvo, V., Fantini, C., Ferrucci, S. M., Flori, M. L., Fontana, E., Foti, C., Francalanci, S., Frasin, L. A., Gola, M., Gravante, M., Guastaferro, D., Ingordo, V., Lauriola, M. M., Leghissa, P., Lisi, P., Lombardi, P., Lorenzini, M., Magrini, L., Marone, G., Martina, E., Mascagni, P., Matteinichiari, M., Meligeni, L., Melino, M., Milanesi, N., Molinu, A. A., Monfrecola, G., Morelli, P., Motolese, A., Musumeci, M. L., Napolitano, M., Nasca, M. R., Paganini, P., Papini, M., Pasolini, G., Peroni, A., Peserico, A., Piras, V., Pugliese, A., Raponi, F., Raviolo, P. D., Rebora, A., Recchia, G. P., Riva, F., Rossi, M., Ruggieri, M., Saggiorato, F., Sartorelli, P., Schena, D., Schettino, A., Spano, G., Stinchi, C., Taddei, L., Tasin, L., Tramontana, M., Valsecchi, R. H., Vascellaro, A., and Venturini, M.

Abstract

Patch testing is the standard procedure used to diagnose allergic contact dermatitis. It is an in-vivo test, which reproduces the reaction to a contact allergen. This in-vivo test aims to reproduce the elicitation phase of allergic contact dermatitis and is performed applying allergens under occlusion on the skin under standardized conditions. These guidelines for the best practice in performing patch test have been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Society of Contact Dermatitis (ESCD) and on the basis of the SIDAPA guidelines.

Published
2019

3. Italian guidelines for therapy of atopic dermatitis-Adapted from consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis)

Author

Damiani, G, Calzavara-Pinton, P, Stingeni, L, Hansel, K, Cusano, F, 'Skin Allergy' Group of SIDeMaST, 'ADOI' (Associazione Dermatologi Ospedalieri Italiani), 'SIDAPA' (Società Italiana di Dermatologia Allergologica Professionale, e Ambientale), Agostinelli, D., Albertazzi, D., Angelini, G, Angerosa, F, Arigliano, Pl, Assalve, D, Ayala, F, Barbagallo, T, Belloni-Fortina, A, Berta, M, Biale, C, Bianchi, L, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Bragazzi, Nl, Brambilla, L, Bressan, M, Brunasso, Amg, Bruni, F, Bruni, P, Caccavale, S, Calogiuri, G, Cannavò, Sp, Carugno, A, Cataldi, I, Chiarelli, G, Cirla, Am, Corazza, M, Cossutta, M, Cova, L, Cristaudo, A, Danese, P, Dal Canton, M, De Pità, O, De Salvo, P, Donini, M, Fantini, F, Ferrucci, Sm, Flori, Ml, Fontana, E, Foti, C, Francalci, S, Frasin, La, Gallo, R, Gasparini, G, Gola, M, Gravante, M, Guarnieri, F, Guastaferro, D, Ingordo, V, Lauriola, Mm, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Malara, G, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteini Chiari, M, Meligeni, L, Melino, M, Miccio, L, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, Ml, Naldi, L, Napolitano, M, Nasca, Mr, Pacifico, A, Paganini, P, Papini, M, Pasolini, G, Patruno, C, Pellegrino, M, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, Pd, Rebora, A, Recchia, Gp, Riva, F, Romita, P, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spanò, G, Stinchi, C, Tasin, L, Tramontana, M, Taddei, L, Valsecchi, Re, Russo, F, Vascellaro, A, Venturini, M, Vincenzi, C, Virgili, A, Pigatto PDM, Zucca M)., Damiani, G, Calzavara-Pinton, P, Stingeni, L, Hansel, K, Cusano, F, Pigatto, P, Agostinelli, D, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Barbagallo, T, Belloni-Fortina, A, Berta, M, Biale, C, Bianchi, L, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Bragazzi, N, Brambilla, L, Bressan, M, Brunasso, A, Bruni, F, Bruni, P, Caccavalle, S, Calogiuri, G, Cannavo, S, Carugno, A, Cataldi, I, Chiarelli, G, Cirla, A, Corazza, M, Cossutta, M, Cova, L, Cristaudo, A, Danese, P, Dal Canton, M, Depita, O, De Salvo, P, Donini, M, Fantini, F, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalci, S, Frasin, L, Gallo, R, Gasparini, G, Gola, M, Gravante, M, Guarnieri, F, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Malara, G, Magrini, L, Marone, G, Martina, E, Mascagni, P, Chiari, M, Meligeni, L, Melino, M, Miccio, L, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Naldi, L, Napolitano, M, Nasca, M, Pacifico, A, Paganini, P, Papini, M, Pasolini, G, Patruno, C, Pellegrino, M, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Romita, P, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Tasin, L, Tramontana, M, Taddei, L, Valsecchi, R, Russo, F, Vascellaro, A, Venturini, M, Vincenzi, C, Virgili, A, Zucca, M, G., Damiani, P., Calzavara-Pinton, L., Stingeni, K., Hansel, F., Cusano, L Arigliano, P, L Bragazzi, N, G Brunasso, A M, Caccavale, S, P Cannavò, S, M Cirla, A, De Pità, O, M Ferrucci, S, L Flori, M, A Frasin, L, M Lauriola, M, Matteini Chiari, M, L Musumeci, M, R Nasca, M, D Raviolo, P, P Recchia, G, Spanò, G, E Valsecchi, R, and P. D. M., Pigatto

Subjects
dermatological agents, Cultural context, atopic eczema, Dermatitis, azatioprin, 030207 dermatology & venereal diseases, 0302 clinical medicine, cclosporin, topical, atopic dermatitis, cyclosporin, dupilumab, methotrexate, phototherapy, topicals, Adult, Biological Products, Child, Dermatitis, Atopic, Dermatologic Agents, Dermatology, Humans, Italy, Practice Guidelines as Topic, General Medicine, Atopic dermatitis, Dupilumab, 030220 oncology & carcinogenesis, Revolutionary change, Biological Product, Human, atopic dermatiti, medicine.medical_specialty, atopic dermatitis, atopic eczema, azatioprin, cclosporin, dupilumab, methotrexate, phototherapy, topicals, adult, biological products, child, dermatological agents, Dermatologic Agent, Socio-culturale, Context (language use), Atopic, 03 medical and health sciences, Therapeutic approach, Settore MED/35, Eczema atopic dermatitis, medicine, business.industry, medicine.disease, Family medicine, Good clinical practice, business
Abstract

Atopic dermatitis (AD) therapeutic approach calls for a long-term treatment. Treatment options for AD have recently undergone a revolutionary change by the introduction of the first biologic drug. Availability in daily practice of the last version of international AD guidelines, taking peculiarities of the country into account, can contribute to good clinical practice in Italy. To adapt European Dermatology Forum (EDF) guidelines for AD to the Italian medical–legal context, the EDF guidelines were assessed independently by two independent Italian renowned experts in the field and further integrated with articles published and systematically reviewed before May 2019. The first draft was collegially corrected and updated by the members of the SIDEMAST, ADOI, and SIDAPA. Recommendation levels (A; B; C; D) were graded based on the evidence levels (1–4). The adapted guidelines presented here focus on topical and systemic therapies in AD patients, both children and adults. As opposed to previous Italian guidelines, they include indications about biologics. New relevant evidence available from very recent literature and peculiarities of the Italian medical and legal context have been integrated in the revision process. If compared to general guidelines for AD not adapted to a specific national and cultural context, a revision for specific Italian needs is now available: It comprises the option of implementing the new biologic treatments and is likely to provide an important contribution to the improvement of clinical practice in Italy. Cooperation between patients, dermatologists, allergologists, and pediatricians remains mandatory in AD management. The authors of the present revision recommend an update of the Italian guidelines to be performed at least every second year.

Published
2019

4. Italian Guidelines in Patch Testing - adapted from the European Society of Contact Dermatitis (ESCD)

Author

Stingeni, Luca, Bianchi, Leonardo, Hansel, Katharina, Corazza, Monica, Gallo, Rosella, Guarneri, Fabrizio, Patruno, Cataldo, Rigano, Luigi, Romita, Paolo, Pigatto, Paolo D, Calzavara-Pinton, Piergiacomo, Agostinelli, D, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, Pl, Assalve, D, Ayala, F, Belloni, Fortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, Sp, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, Am, Cossutta, M, Cova, Lm, Cristaudo, A, Dal Canton, M, Damiani, G, Danese, P, De Salvo, V, Fantini, C, Ferrucci, Sm, Flori, Ml, Fontana, E, Foti, C, Francalanci, S, Frasin, La, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, Mm, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteini, Chiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, Aa, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, Ml, Napolitano, M, Nasca, Mr, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, Pd, Rebora, A, Recchia, Gp, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, Rh, Vascellaro, A, Venturini, M, Vincenzi, C, Virgili, A, Zucca, M, Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Pigatto, Pd, Calzavara-Pinton, P, 'Skin Allergy' group of SIDeMaST and 'SIDAPA' (Agostinelli, D, Arigliano, Pl, Belloni Fortina, A, Cannavò, Sp, Cirla, Am, Cova, Lm, Dal Canton, M, De Salvo, V, Ferrucci, Sm, Flori, Ml, Frasin, La, Lauriola, Mm, Matteini Chiari, M, Molinu, Aa, Musumeci, Ml, Nasca, Mr, Raviolo, Pd, Recchia, Gp, Valsecchi, Rh, Vincenzi, C, Virgili, A, and Zucca, M).

Subjects
Dermatitis, contact, Guideline, Patch tests, medicine.medical_specialty, Allergic Contact, Socio-culturale, Dermatitis, Dermatology, Patch tests, Guideline, contact, Patch test, Patch testing, Standard procedure, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Dermatitis, contact, Allergens, Dermatitis, Allergic Contact, Humans, Italy, Patch Tests, medicine, Allergic contact dermatitis, business.industry, Contact dermatitis, medicine.disease, Test (assessment), Family medicine, business
Abstract

Patch testing is the standard procedure used to diagnose allergic contact dermatitis. It is an in-vivo test, which reproduces the reaction to a contact allergen. This in-vivo test aims to reproduce the elicitation phase of allergic contact dermatitis and is performed applying allergens under occlusion on the skin under standardized conditions. These guidelines for the best practice in performing patch test have been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Society of Contact Dermatitis (ESCD) and on the basis of the SIDAPA guidelines.

Published
2019

9. Quality control exercise of the Italian Monitoring Network in Aerobiology A.I.A.-R.I.M.A.®

Author

Bonini, M., Ugolotti, M., Cislaghi, G., Colombo, P., Molinari, A., Vercelloni, S., Chiodini, E., Pini, A., Paganoni, B., Biale, C., Gibelli, N., Pignatti, P., Voltolini, S., Mezzetta, S., Rossi, G., Ferri, M., Ceretta, E., Marcer, G., Bordin, A., Pace, Loretta Giuseppina, Casilli, M., Tedeschini, E., Timorato, V., Ghitarrini, S., Russo, M., Patella, V., Calabrese, R. M., Cuiliano, A., DI FLURI, G., Graziani, A., Arsieni, A., and Albertini, R.

Published
2017

10. Controllo di qualità; ring test della Rete Italiana di Monitoraggio Aerobiologico (R.I.M.A.)

Author

Bonini, M, Testoni, C, Cislaghi, G, Colombo, P, Patella, V, Calabrese, Rm, Giuliano, A, Di fluri, G, Chiodini, E, Russo, M, Voltolini, S, Mezzetta, S, Molinari, A, Vercelloni, S, Pace, Loretta Giuseppina, Casilli, M, Biale, C, Gibelli, N, Pignatti, P, Pini, A, Paganoni, B, Occello, L, Ferri, M, Ceretta, E, Graziani, A, Marcer, G, Bordin, A, Tedeschini, E, Timorato, V, Ghitarrini, S, Ugolotti, M, and Albertini, R.

Published
2015

11. Il controllo di qualità della R.I.M.A.®: prima esperienza in A.I.A

Author

Travaglini, A., Biale, C., Bonini, M., Brighetti, M. A., Casilli, M., Cislaghi, G., Colombo, P., D’Amato, G., Gibelli, N., Graziani, A., Greco, F., Ierardi, G., Mezzetta, S., Moscato, G., Pace, Loretta Giuseppina, Pignatti, P., Pugliese, L., Russo, M., Salvemini, F., Serra, M. C., Vinciguerra, F., and Voltolini, S.

Published
2012

19. An epidemiological survey on the allergological importance of some emerging pollens in Italy

Author

Corsico, R., Falagiani, P., Ariano, R., Berra, D., Biale, C., Bonifazi, F., Campi, P., Feliziani, V., Frenguelli, G., Galimberti, M., Gallesio, M. T., Liccardi, G., Loreti, A., Marcer, G., Marcucci, F., Antonio Meriggi, Minelli, M., Nardelli, R., Nardi, G., Negrini, C. A., Papa, G., Piu, G., Pozzan, M., Purello D Ambrosio, F., and Riva, G.

Subjects
Adult, Male, Allergy, Emerging pollens, Middle Aged, Health Surveys, Italy, Surveys and Questionnaires, Prevalence, Respiratory Hypersensitivity, Humans, Pollen, Female, Skin Tests
Abstract

Epidemiological studies on the pollens responsible for allergic diseases throughout Italy are lacking. Routine diagnostic panels consist prevalently of grass, Parietaria, weeds, birch, olive and mugwort. Considering the great variety of Italian geographical areas and the observation of the growing allergological importance of new botanical species (e.g., ambrosia), a survey on pollen species considered "minor" was necessary. A panel of "emerging" pollens (birch, hazelnut, alder, hornbeam, cypress, ragweed) and a routine panel were used to skin prick test 2,934 consecutive outpatients with respiratory pathology of suspected allergic origin, in 21 centers across Italy. A specific questionnaire was compiled. It was found that 20.1% of patients did not react to allergens tested, 28.2% were positive for at least one emerging pollen and 51.7% did not react to emerging pollens but tested positive for at least one allergen from the routine panel. The prevalence of single pollen species was related to geographical areas. Ragweed pollen was shown to provoke asthma much more frequently than other pollens. Hitherto scarcely considered pollens play a considerable role in causing allergic diseases in Italy. In the great majority of patients, positivity for these pollens was associated with positivity to the better recognized group of pollen allergens, although in some cases they were the primary pathogenic agent. We suggest that these more recently considered allergens be included in routine diagnostic panels.

22. A sensitive and practical fluorimetric test for CNT acidic site determination.

Author

Visentin S, Barbero N, Musso S, Mussi V, Biale C, Ploeger R, and Viscardi G

Subjects
Acids chemistry, Fluorescent Dyes chemistry, Fluorometry, Spectrum Analysis, Raman, Thermogravimetry, Nanotubes, Carbon chemistry, Thionins chemistry
Abstract

A sensitive and practical colorimetric test for oxidized carbon nanotubes (CNTs) is described. The assay is based on direct labeling with the commercially available fluorescent dye thionin acetate (THA). This strategy offers the possibility for quantitation of acidic sites in a very fast and easy way.

Published
2010
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23. An epidemiological survey on the allergological importance of some emerging pollens in Italy.

Author

Corsico R, Falagiani P, Ariano R, Berra D, Biale C, Bonifazi F, Campi P, Feliziani V, Frenguelli G, Galimberti M, Gallesio MT, Liccardi G, Loreti A, Marcer G, Marcucci F, Meriggi A, Minelli M, Nardelli R, Nardi G, Negrini CA, Papa G, Piu G, Pozzan M, D'Ambrosio FP, and Riva G

Subjects
Adult, Female, Health Surveys, Humans, Italy epidemiology, Male, Middle Aged, Prevalence, Respiratory Hypersensitivity classification, Skin Tests, Surveys and Questionnaires, Pollen immunology, Respiratory Hypersensitivity epidemiology
Abstract

Epidemiological studies on the pollens responsible for allergic diseases throughout Italy are lacking. Routine diagnostic panels consist prevalently of grass, Parietaria, weeds, birch, olive and mugwort. Considering the great variety of Italian geographical areas and the observation of the growing allergological importance of new botanical species (e.g., ambrosia), a survey on pollen species considered "minor" was necessary. A panel of "emerging" pollens (birch, hazelnut, alder, hornbeam, cypress, ragweed) and a routine panel were used to skin prick test 2,934 consecutive outpatients with respiratory pathology of suspected allergic origin, in 21 centers across Italy. A specific questionnaire was compiled. It was found that 20.1% of patients did not react to allergens tested, 28.2% were positive for at least one emerging pollen and 51.7% did not react to emerging pollens but tested positive for at least one allergen from the routine panel. The prevalence of single pollen species was related to geographical areas. Ragweed pollen was shown to provoke asthma much more frequently than other pollens. Hitherto scarcely considered pollens play a considerable role in causing allergic diseases in Italy. In the great majority of patients, positivity for these pollens was associated with positivity to the better recognized group of pollen allergens, although in some cases they were the primary pathogenic agent. We suggest that these more recently considered allergens be included in routine diagnostic panels.

Published
2000

24. [Epicutaneous sensitization to metals and contact allergic dermatitis: analysis of an ambulatory caseload].

Author

Candura SM, Verni P, Dellabianca A, Biale C, Perfetti L, Calcagno G, Pisati A, and Moscato G

Subjects
Adolescent, Adult, Aged, Ambulatory Care, Child, Female, Humans, Male, Metals adverse effects, Middle Aged, Retrospective Studies, Dermatitis, Allergic Contact etiology
Abstract

We have retrospectively analyzed the clinical and anamnestic features of 233 out-patients (197 females and 36 males; mean age: 33 years; SD: +/- 13.3) with epicutaneous sensitization to metals, who had been examined at the department of allergology of our institution during one year. Among females, nickel sulphate was the metallic salt which most frequently resulted positive at patch testing (87.8% of cases), followed by cobalt chloride (23.6%) and potassium bichromate (10.2%). Nickel was the most common sensitizing metal also in males (58.3%), among whom sensitization to chromate resulted second in order of frequency (30.6%), and sensitization to cobalt was relatively rare (11.1%). In selected cases, the utilization of additional, specific series allowed to document rare cases of sensitization to metallic salts not included in the standard patch test series (copper sulphate, cadmium chloride, zinc stearate, phenylmercuric nitrate). 78 patients were sensitized to more than one metal. Skin sensitivity to metals was often linked to allergic disease familiarity and/or to sensitization toward type I allergens. Allergic contact dermatitis was diagnosed in 80 patients: cutaneous manifestations had been present on average for over four years, sometimes in generalized or persistent form. An occupational contact with the causative metals was identified in 15 cases. However, the occupational origin of the disease could never be documented with certainty, due to concomitance of frequent non-occupational exposures and to lack of information on pre-employment skin sensitivity status. Thus, the value of patch testing, during both pre-employment screening and health surveillance, is emphasized.

Published
1999

25. Local immunotherapy by inhalation of a powder extract in asthma due to house dust mite Dermatophagoides pteronyssinus: a double-blind comparison with parenteral immunotherapy.

Author

Moscato G, Rossi G, Dellabianca A, Pisati A, Vinci G, and Biale C

Subjects
Administration, Inhalation, Adolescent, Adult, Animals, Asthma etiology, Asthma physiopathology, Bronchial Provocation Tests, Double-Blind Method, Female, Humans, Injections, Subcutaneous, Male, Middle Aged, Time Factors, Allergens administration & dosage, Asthma therapy, Desensitization, Immunologic methods, Mites immunology
Abstract

To verify the efficacy and the tolerability of local immunotherapy (LI) by inhalation of a powder extract of house dust mite (HDM), in comparison with parenteral immunotherapy (PI) by injection, 10 patients with asthma due to HDM were studied in a blind fashion. 5 patients (Group A) underwent LI and subcutaneous injections of placebo, 5 patients (Group B) underwent PI and inhalation of lactose for 6 months. In both groups each inhalation was preceded by premedication with disodium cromoglycate (DSCG) (40 mg). In Group A a significant decrease in symptoms score and in peak expiratory flow (PEF)-derived parameters was observed already after 3 months of treatment, and 2 patients lost the late component of the bronchial response to the challenge with HDM. No significant variation was found in bronchial responsiveness to methacholine and ultrasonically nebulized distilled water (UNDW) and in immunologic humoral and cellular parameters in peripheral blood after treatment in either group. No local important adverse reactions were observed in Group A and no systemic side effects were observed in either group. We conclude that LI is as effective as PI, but more rapid in its action, in the treatment of asthma due to HDM. Moreover, LI is locally well tolerated, providing DSCG is inhaled before each therapeutic inhalation, and does not induce systemic side effects.

Published
1991

26. [Asthma caused by sodium p-toluene-n-chloro-sulfonamide: observations on a clinical case].

Author

Dellabianca A, Vinci G, Biale C, Pisati A, and Moscato G

Subjects
Asthma diagnosis, Humans, Male, Middle Aged, Occupational Diseases diagnosis, Asthma chemically induced, Chloramines adverse effects, Disinfectants adverse effects, Occupational Diseases chemically induced, Tosyl Compounds
Abstract

We describe the case of a patient exposed to chloramine-T who experienced severe asthmatic symptoms when spraying chloramine-T solutions. The patient used chloramine-T as a sterilising agent in medical facilities. Occupational asthma due to chloramine-T was diagnosed by means of specific bronchial provocation test (occupational type). We stress the risk of exposure to high levels of chloramine-T and the importance of this compound as a cause of occupational asthma.

Published
1988

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