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3. Sixty-Day Mortality Among 520 Italian Hospitalized COVID-19 Patients According to the Adopted Ventilatory Strategy in the Context of an Integrated Multidisciplinary Clinical Organization: A Population-Based Cohort Study

Author

Potalivo A, Montomoli J, Facondini F, Sanson G, Lazzari Agli LA, Perin T, Cristini F, Cavagna E, De Giovanni R, Biagetti C, Panzini I, Ravaioli C, Bitondo MM, Guerra D, Giuliani G, Mosconi E, Guarino S, Marchionni E, Gangitano G, Valentini I, Giampaolo L, Muratore F, and Nardi G

Subjects
covid-19, mechanical ventilation, mortality, noninvasive ventilation, multidisciplinary team approach, ards, Infectious and parasitic diseases, RC109-216
Abstract

Antonella Potalivo,1,* Jonathan Montomoli,1,* Francesca Facondini,1 Gianfranco Sanson,2 Luigi Arcangelo Lazzari Agli,3,4 Tiziana Perin,5 Francesco Cristini,6 Enrico Cavagna,7 Raffaella De Giovanni,8 Carlo Biagetti,6 Ilaria Panzini,9 Cinzia Ravaioli,10 Maria Maddalena Bitondo,1 Daniela Guerra,1 Giovanni Giuliani,1 Elena Mosconi,1 Sonia Guarino,1 Elisa Marchionni,6 Gianfilippo Gangitano,5 Ilaria Valentini,3,4 Luca Giampaolo,8 Francesco Muratore,7 Giuseppe Nardi1 1Department of Anaesthesia and Intensive Care, Infermi Hospital, AUSL della Romagna, Rimini, Italy; 2Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy; 3Department of Pneumology, Infermi Hospital, Rimini, Italy; 4Ceccarini Hospital, AUSL della Romagna, Riccione, Italy; 5Department of Emergency Medicine, Infermi Hospital, AUSL Della Romagna, Rimini, Italy; 6Department of Infectious Diseases, Infermi Hospital, AUSL della Romagna, Rimini,Italy; 7Department of Radiology, Infermi Hospital, AUSL della Romagna, Rimini, Italy; 8Department of Internal Medicine, Cervesi Hospital, AUSL della Romagna, Cattolica, Italy; 9Department of Clinical Research, AUSL della Romagna, Ravenna, Italy; 10Ausl della Romagna Health Care Service Direction, Ravenna, Italy*These authors contributed equally to this workCorrespondence: Giuseppe NardiDepartment of Anaesthesia and Intensive Care, Infermi Hospital, AUSL della Romagna, Viale Settembrini 2, Rimini 47921, ItalyTel +39 0541-705254Fax +39 0541 705886Email 4doctornardi@gmail.comPurpose: Although the decision of which ventilation strategy to adopt in COVID-19 patients is crucial, yet the most appropriate means of carrying out this undertaking is not supported by strong evidence. We therefore described the organization of a province-level healthcare system during the occurrence of the COVID-19 epidemic and the 60-day outcomes of the hospitalized COVID-19 patients according to the respiratory strategy adopted given the limited available resources.Patients and Methods: All COVID-19 patients (26/02/2020– 18/04/2020) in the Rimini Province of Italy were included in this population-based cohort study. The hospitalized patients were classified according to the maximum level of respiratory support: oxygen supplementation (Oxygen group), non-invasive ventilation (NIV-only group), invasive mechanical ventilation (IMV-only group), and IMV after an NIV trial (IMV-after-NIV group). Sixty-day mortality risk was estimated with a Cox proportional hazard analysis adjusted by age, sex, and administration of steroids, canakinumab, and tocilizumab.Results: We identified a total of 1,424 symptomatic patients: 520 (36.5%) were hospitalized, while 904 (63.5%) were treated at home with no 60-day deaths. Based on the respiratory support, 408 (78.5%) were assigned to the Oxygen group, 46 (8.8%) to the NIV-only group, 25 (4.8%) to the IMV-after-NIV group, and 41 (7.9%) to the IMV-only group. There was no significant difference in the PaO2/FiO2 at IMV inception in the IMV-after-NIV and IMV-only groups (p=0.9). Overall 60-day mortality was 24.2% (Oxygen: 23.0%; NIV-only: 19.6%; IMV-after-NIV: 32.0%; IMV-only: 36.6%; p=0.165). Compared with the Oxygen group, the adjusted 60-day mortality risk significantly increased in the IMV-after-NIV (HR 2.776; p=0.024) and IMV-only groups (HR 2.966; p=0.001).Conclusion: This study provided a population-based estimate of the impact of the COVID-19 outbreak in a severely affected Italian province. A similar 60-day mortality risk was found for patients undergoing immediate IMV and those intubated after an NIV trial with favorable outcomes after prolonged IMV.Keywords: COVID-19, mechanical ventilation, mortality, noninvasive ventilation, multidisciplinary team approach, ARDS

Published
2020

4. The Cosmic Origins Spectrograph: On-Orbit Instrument Performance

Author

Osterman, S., Green, J., Froning, C., Béland, S., Burgh, E., France, K., Penton, S., Delker, T., Ebbets, D., Sahnow, D., Bacinski, J., Kimble, R., Andrews, J., Wilkinson, E., McPhate, J., Siegmund, O., Ake, T., Aloisi, A., Biagetti, C., Diaz, R., Dixon, W., Friedman, S., Ghavamian, P., Goudfrooij, P., Hartig, G., Keyes, C., Lennon, D., Massa, D., Niemi, S., Oliveira, C., Osten, R., Proffitt, C., Smith, T., and Soderblom, D.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The Cosmic Origins Spectrograph (COS) was installed in the Hubble Space Telescope in May, 2009 as part of Servicing Mission 4 to provide high sensitivity, medium and low resolution spectroscopy at far- and near-ultraviolet wavelengths (FUV, NUV). COS is the most sensitive FUV/NUV spectrograph flown to date, spanning the wavelength range from 900{\AA} to 3200{\AA} with peak effective area approaching 3000 cm^2. This paper describes instrument design, the results of the Servicing Mission Orbital Verification (SMOV), and the ongoing performance monitoring program., Comment: 9 pages, 7 figures, submitted to Astrophysics and Space Science

Published
2010
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5. Containment of carbapenem-resistant Enterobacterales colonisations and infections: Results from an integrated infection control intervention in a large hospital trust of northern Italy

Author

Biagetti, C., primary, Tatarelli, P., additional, Tebano, G., additional, Casolari, S., additional, Fantini, M., additional, Malavolti, M., additional, Amadori, A., additional, Tura, GA, additional, Sambri, V., additional, Minghetti, M., additional, Grilli, R., additional, and Gagliotti, C., additional

Published
2023
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6. P483 IMPACT OF AN ENDOCARDITIS TEAM ON PROGNOSIS: PRELIMINARY RESULTS

Author

Di Domenico, A, primary, Carigi, S, additional, Amati, S, additional, Di Giannuario, G, additional, Di Cesare, A, additional, Farneti, L, additional, Sarti, A, additional, Tripodi, A, additional, Moscatelli, G, additional, Kety, L, additional, Vandi, G, additional, Mele, E, additional, Biagetti, C, additional, and Santarelli, A, additional

Published
2023
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7. Real-life comparison of mortality in patients with SARS-CoV-2 infection at risk for clinical progression treated with molnupiravir or nirmatrelvir plus ritonavir during the Omicron era in Italy: a nationwide, cohort study

Author

Torti, C, Olimpieri, P, Bonfanti, P, Tascini, C, Celant, S, Tacconi, D, Nicastri, E, Tacconelli, E, Cacopardo, B, Perrella, A, Buccoliero, G, Parruti, G, Bassetti, M, Biagetti, C, Giacometti, A, Erne, E, Frontuto, M, Lanzafame, M, Summa, V, Spagnoli, A, Vestri, A, Di Perri, G, Russo, P, Palù, G, Torti, Carlo, Olimpieri, Pier Paolo, Bonfanti, Paolo, Tascini, Carlo, Celant, Simone, Tacconi, Danilo, Nicastri, Emanuele, Tacconelli, Evelina, Cacopardo, Bruno, Perrella, Alessandro, Buccoliero, Giovanni Battista, Parruti, Giustino, Bassetti, Matteo, Biagetti, Carlo, Giacometti, Andrea, Erne, Elke Maria, Frontuto, Maria, Lanzafame, Massimiliano, Summa, Valentina, Spagnoli, Alessandra, Vestri, Annarita, Di Perri, Giovanni, Russo, Pierluigi, Palù, Giorgio, Torti, C, Olimpieri, P, Bonfanti, P, Tascini, C, Celant, S, Tacconi, D, Nicastri, E, Tacconelli, E, Cacopardo, B, Perrella, A, Buccoliero, G, Parruti, G, Bassetti, M, Biagetti, C, Giacometti, A, Erne, E, Frontuto, M, Lanzafame, M, Summa, V, Spagnoli, A, Vestri, A, Di Perri, G, Russo, P, Palù, G, Torti, Carlo, Olimpieri, Pier Paolo, Bonfanti, Paolo, Tascini, Carlo, Celant, Simone, Tacconi, Danilo, Nicastri, Emanuele, Tacconelli, Evelina, Cacopardo, Bruno, Perrella, Alessandro, Buccoliero, Giovanni Battista, Parruti, Giustino, Bassetti, Matteo, Biagetti, Carlo, Giacometti, Andrea, Erne, Elke Maria, Frontuto, Maria, Lanzafame, Massimiliano, Summa, Valentina, Spagnoli, Alessandra, Vestri, Annarita, Di Perri, Giovanni, Russo, Pierluigi, and Palù, Giorgio

Abstract

Background: Comparative data on mortality in COVID-19 patients treated with molnupiravir or with nirmatrelvir plus ritonavir are inconclusive. We therefore compared all-cause mortality in community-dwelling COVID-19 patients treated with these drugs during the Omicron era. Methods: Data collected in the nationwide, population-based, cohort of patients registered in the database of the Italian Medicines Agency (AIFA) were used. To increase completeness of the recorded deaths and date correctness, a cross-check with the National Death Registry provided by the Ministry of the Interior was performed. We included in this study all patients infected by SARS-CoV-2 treated within 5 days after the test date and symptom onset between February 8 and April 30, 2022. All-cause mortalities by day 28 were compared between the two treatment groups after balancing for baseline characteristics using weights obtained from a gradient boosting machine algorithm. Findings: In the considered timeframe, 17,977 patients treated with molnupiravir and 11,576 patients with nirmatrelvir plus ritonavir were included in the analysis. Most patients (25,617/29,553 = 86.7%) received a full vaccine course including the booster dose. A higher crude incidence rate of all-cause mortality was found among molnupiravir users (51.83 per 100,000 person-days), compared to nirmatrelvir plus ritonavir users (22.29 per 100,000 person-days). However, molnupiravir-treated patients were older than those treated with nirmatrelvir plus ritonavir and differences between the two populations were found as far as types of co-morbidities were concerned. For this reason, we compared the weight-adjusted cumulative incidences using the Aalen estimator and found that the adjusted cumulative incidence rates were 1.23% (95% CI 1.07%–1.38%) for molnupiravir-treated and 0.78% (95% CI 0.58%–0.98%) for nirmatrelvir plus ritonavir-treated patients (adjusted log rank p = 0.0002). Moreover, the weight-adjusted mixed-effect Cox model i

Published
2023

11. The Cosmic Origins Spectrograph: on-orbit instrument performance

Author

Osterman, S., Green, J., Froning, C., Béland, S., Burgh, E., France, K., Penton, S., Delker, T., Ebbets, D., Sahnow, D., Bacinski, J., Kimble, R., Andrews, J., Wilkinson, E., McPhate, J., Siegmund, O., Ake, T., Aloisi, A., Biagetti, C., Diaz, R., Dixon, W., Friedman, S., Ghavamian, P., Goudfrooij, P., Hartig, G., Keyes, C., Lennon, D., Massa, D., Niemi, S., Oliveira, C., Osten, R., Proffitt, C., Smith, T., and Soderblom, D.

Published
2011
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12. The Cosmic Origins Spectrograph: on-orbit instrument performance

Author

Osterman, S., primary, Green, J., additional, Froning, C., additional, Béland, S., additional, Burgh, E., additional, France, K., additional, Penton, S., additional, Delker, T., additional, Ebbets, D., additional, Sahnow, D., additional, Bacinski, J., additional, Kimble, R., additional, Andrews, J., additional, Wilkinson, E., additional, McPhate, J., additional, Siegmund, O., additional, Ake, T., additional, Aloisi, A., additional, Biagetti, C., additional, Diaz, R., additional, Dixon, W., additional, Friedman, S., additional, Ghavamian, P., additional, Goudfrooij, P., additional, Hartig, G., additional, Keyes, C., additional, Lennon, D., additional, Massa, D., additional, Niemi, S., additional, Oliveira, C., additional, Osten, R., additional, Proffitt, C., additional, Smith, T., additional, and Soderblom, D., additional

Published
2011
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13. Clinical, epidemiological and virological features of acute hepatitis B in Italy

Author

Zuccaro O, Romanò L, Mele A, Mariano A, Clementi M, Tosti ME, Taliani G, Galli C, Zanetti AR, Spada E, Raise E, Eseme FE, Maio G, Rummo G, Maio P, Di Giuli C, Bellissima P, Bonfante S, Chiriacò P, Cacopardo B, Blanc P, Palattella S, Santantonio T, Guastadisegni A, Amoroso P, Fabris P, Giordani MT, Vullo V, Giuberti T, Schivazzappa S, Trezzi M, Biagetti C, Pocaterra D, Sagnelli E, Messina V, Antonucci G, Spallanzani L, Vairo F, Marinelli M, Paladini S, Tagliacarne C., VERUCCHI, GABRIELLA, Zuccaro O, Romanò L, Mele A, Mariano A, Clementi M, Tosti ME, Taliani G, Galli C, Zanetti AR, Spada E, Raise E, Eseme FE, Maio G, Rummo G, Maio P, Di Giuli C, Bellissima P, Bonfante S, Chiriacò P, Cacopardo B, Blanc P, Palattella S, Santantonio T, Guastadisegni A, Amoroso P, Fabris P, Giordani MT, Vullo V, Giuberti T, Schivazzappa S, Trezzi M, Verucchi G, Biagetti C, Pocaterra D, Sagnelli E, Messina V, Antonucci G, Spallanzani L, Vairo F, Marinelli M, Paladini S, Tagliacarne C, Zuccaro, O., Romano, L., Mele, A., Mariano, A., Clementi, M., Tosti, M. E., Taliani, G., Galli, C., Zanetti, A. R., and Spada, E.

Subjects
Adult, Male, Microbiology (medical), Hepatitis B virus, medicine.medical_specialty, Adolescent, Genotype, Epidemiology, Genotypes, Gene mutation, medicine.disease_cause, Cohort Studies, Young Adult, Basal (phylogenetics), 80 and over, medicine, Humans, Hepatitis B Vaccines, Prospective Studies, Acute infection, Hepatitis B, Mutations, Risk factors, Aged, Acute Disease, Aged, 80 and over, Female, Follow-Up Studies, Hepatitis B Core Antigens, Italy, Middle Aged, Infectious Diseases, business.industry, Promoter, General Medicine, medicine.disease, Virology, Mutation, Immunology, Acute hepatitis B, business
Abstract

Purpose: To evaluate the association of hepatitis B virus (HBV) genotypes, basal core promoter (BCP)/precore (PC) and S gene mutations with the clinical-epidemiological characteristics of acute hepatitis B (AHB) in Italy. Methods: During July 2005–January 2007, 103 symptomatic AHB patients were enrolled and prospectively followed up at 15 national hospitals. HBV genotypes, BCP/PC and S gene variants were determined by nested-PCR and direct sequence analysis. Results: Genotype D, A and F were detected in 49, 45 and 6% of patients, respectively. BCP, PC, and BCP plus PC variants were found in 3.1, 11.3 and 7.2% of patients, respectively. At enrollment, 68.3% of patients were hepatitis B e antigen (HBeAg)-positive and 31.7% HBeAg-negative. BCP/PC mutations were more common in HBeAg-negative than in HBeAg-positive patients (p&nbsp

Published
2015
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15. The Great Observatories Origins Deep Survey: Initial results from optical and near-infrared imaging

Author

Giavalisco, M., Ferguson, H. C., Koekemoer, A. M., Dickinson, M., Alexander, D. M., Bauer, F. E., Bergeron, J., Biagetti, C., Brandt, W. N., Casertano, S., Cesarsky, C., Chatzichristou, E., Conselice, C., Stefano Cristiani, Da Costa, L., Dahlen, T., Mello, D., Eisenhardt, P., Erben, T., Fall, S. M., Fassnacht, C., Fosbury, R., Fruchter, A., Gardner, J. P., Grogin, N., Hook, R. N., Hornschemeier, A. E., Idzi, R., Jogee, S., Kretchmer, C., Laidler, V., Lee, K. S., Livio, M., Lucas, R., Madau, P., Mobasher, B., Moustakas, L. A., Nonino, M., Padovani, P., Papovich, C., Park, Y., Ravindranath, S., Renzini, A., Richardson, M., Riess, A., Rosati, P., Schirmer, M., Schreier, E., Somerville, R. S., Spinrad, H., Stern, D., Stiavelli, M., Strolger, L., Urry, C. M., Vandame, B., Williams, R., and Wolf, C.

Subjects
Physics, Active galactic nucleus, Astrophysics::High Energy Astrophysical Phenomena, Astrophysics (astro-ph), Infrared telescope, Astrophysics::Instrumentation and Methods for Astrophysics, FOS: Physical sciences, Astronomy and Astrophysics, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, Hubble Ultra-Deep Field, Advanced Camera for Surveys, Galaxy, Extended Groth Strip, Space and Planetary Science, Observatory, Chandra Deep Field South, Astrophysics::Solar and Stellar Astrophysics, Astrophysics::Galaxy Astrophysics
Abstract

This Special Issue of the Astrophysical Journal Letters is dedicated to presenting initial results from the Great Observatories Origins Deep Survey (GOODS) that are primarily, but not exclusively, based on multi--band imaging data obtained with the {\it Hubble Space Telescope} ({\it HST}) and the Advanced Camera for Surveys (ACS). The survey covers roughly 320 square arcminutes in the ACS F435W, F606W, F814W, and F850LP bands, divided into two well-studied fields. Existing deep observations from the {\it Chandra} X-ray Observatory (\cxo) and ground-based facilities are supplemented with new, deep imaging in the optical and near-infrared from the European Southern Observatory (ESO) and from the Kitt Peak National Observatory (KPNO). Deep observations with the {\it Space Infrared Telescope Facility} (SIRTF) are scheduled. Reduced data from all facilities are being released worldwide within three to six months of acquisition. Together, this data set provides two deep reference fields for studies of distant normal and active galaxies, supernovae, and faint stars in our own galaxy. This paper serves to outline the survey strategy and describe the specific data that have been used in the accompanying letters, summarizing the reduction procedures and sensitivity limits., 19 pages, 4 figures. Accepted for publication in the Astrophysical Journal, Letters. See manuscript for the full authorship list. The data and the GOODS-group papers can be found at http://www.stsci.edu/science/goods/

Published
2016
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18. Poster session 1: Wednesday 3 December 2014, 09:00-16:00Location: Poster area

Author

Tong, L., Huang, C., Ramalli, A., Tortoli, P., Luo, J., D'Hooge, J., Tzemos, N., Mordi, I., Bishay, T., Negishi, T., Hristova, K., Kurosawa, K., Bansal, M., Thavendiranathan, P., Yuda, S., Popescu, B., Vinereanu, D., Penicka, M., Marwick, T., Hamed, W., Kamel, M., Yaseen, R., El Barbary, H., Nemes, A., Kis, O., Gavaller, H., Kanyo, E., Forster, T., Angelis, A., Vlachopoulos, C., Ioakimidis, N., Felekos, I., Chrysohoou, C., Aznaouridis, K., Abdelrasoul, M., Terentes, D., Ageli, K., Stefanadis, C., Kurnicka, K., Domienik Karlowicz, J., Lichodziejewska, B., Goliszek, S., Grudzka, K., Krupa, M., Dzikowska Diduch, O., Ciurzynski, M., Pruszczyk, P., Capllonch, F. G., Ayerbe, J. L., Teis, A., Ferrer, E., Vallejo, N., Junca, G., Pla, R., Bayes Genis, A., Schwaiger, J., Knight, D., Gallimore, A., Schreiber, B., Handler, C., Coghlan, J., Bruno, R. M., Giardini, G., Malacrida, S., Catuzzo, B., Armenia, S., Brustia, R., Ghiadoni, L., Cauchy, E., Pratali, L., Kim, K., Lee, K., Cho, J., Yoon, H., Ahn, Y., Jeong, M., Park, J., Cho, S., Nastase, O., Enache, R., Mateescu, A., Botezatu, D., Ginghina, C., Gu, H., Sinha, M., Simpson, J., Chowienczyk, P., Fazlinezhad, A., Behesthi, A. T., Homaei, F., Mostafavi, H., Hosseini, G., Bakaeiyan, M., Boutsikou, M., Petrou, E., Dimopoulos, A., Dritsas, A., Leontiadis, E., Karatasakis, G., Sahin, S. T., Yurdakul, S., Yilmaz, N., Cengiz, B., Cagatay, Y., Aytekin, S., Yavuz, S., Karlsen, S., Dahlslett, T., Grenne, B., Sjoli, B., Smiseth, O., Edvardsen, T., Brunvand, H., Nasr, G., Nasr, A., Eleraki, A., Elrefai, S., Sonecki, P., Gustafsson, U., Naar, J., Stahlberg, M., Cerne, A., Capotosto, L., Rosato, Edoardo, D'Angeli, I., Azzano, A., Truscelli, G., Maio, M. D., Salsano, F., Terzano, C., Mangieri, E., Vitarelli, A., Renard, S., Najih, H., Mancini, J., Jacquier, A., Haentjens, J., Gaubert, J., Habib, G., Caminiti, G., D'Antoni, V., Cardaci, V., Conti, V., Volterrani, M., Ahn, J., Kim, D., Lee, H., Iliuta, L., Kim, S., Ryu, S., Ko, C., Pyun, Y., Yoon, S., Iudice, F. L., Esposito, R., Lembo, M., Santoro, C., Ballo, P., Mondillo, S., Simone, G. D., Galderisi, M., Hwang, Y., Kim, J., Moon, K., Yoo, K., Kim, C., Tagliamonte, E., Rigo, F., Cirillo, T., Caruso, A., Astarita, C., Cice, G., Quaranta, G., Romano, C., Capuano, N., Calabro', R., Zagatina, A., Zhuravskaya, N., Guseva, O., Huttin, O., Benichou, M., Voilliot, D., Venner, C., Micard, E., Girerd, N., Sadoul, N., Moulin, F., Juilliere, Y., Selton Suty, C., Baron, T., Christersson, C., Johansson, K., Flachskampf, F., Lee, S., Lee, J., Hur, S., Yun, J., Song, S., Kim, W., Ko, J., Nyktari, E., Bilal, S., Ali, S., Izgi, C., Prasad, S., Aly, M., Kleijn, S., Kandil, H., Kamp, O., Beladan, C., Calin, A., Rosca, M., Craciun, A., Gurzun, M., Calin, C., Mornos, C., Mornos, A., Ionac, A., Cozma, D., Crisan, S., Popescu, I., Ionescu, G., Petrescu, L., Camacho, S., Chulian, S. G., Carmona, R., Diaz, E., Giraldez, A., Gutierrez, A., Toro, R., Benezet, J., Antonini Canterin, F., Vriz, O., Carrubba, S. L., Poli, S., Leiballi, E., Zito, C., Careri, S., Caruso, R., Pellegrinet, M., Nicolosi, G., Kong, W., Kyu, K., Wong, R., Tay, E., Yip, J., Yeo, T., Poh, K., Correia, M., Delgado, A., Marmelo, B., Correia, E., Abreu, L., Cabral, C., Gama, P., Santos, O., Rahman, M., Borges, I. P., Peixoto, E., Peixoto, R., Marcolla, V., Okura, H., Kanai, M., Murata, E., Kataoka, T., Stoebe, S., Tarr, A., Pfeiffer, D., Hagendorff, A., Generati, G., Bandera, F., Pellegrino, M., Alfonzetti, E., Labate, V., Guazzi, M., Kuznetsov, V., Yaroslavskaya, E., Pushkarev, G., Krinochkin, D., Zyrianov, I., Carigi, S., Baldazzi, F., Bologna, F., Amati, S., Venturi, P., Grosseto, D., Biagetti, C., Fabbri, E., Arlotti, M., Piovaccari, G., Rahbi, H., Abdulhaq, A. B., Tleyjeh, I., Costantino, M., Tarsia, G., Innelli, P., Dores, E., Esposito, G., Matera, A., Trimarco, B., Mukred, K., Ashurov, R., Tanzilli, G., Merlo, M., Gigli, M., Stolfo, D., Pinamonti, B., Canterin, F. A., Muca, M., D'Angelo, G., Scapol, S., Nucci, M. D., Sinagra, G., Behaghel, A., Feneon, D., Fournet, M., Thebault, C., Martins, R., Mabo, P., Leclercq, C., Daubert, C., Donal, E., Pal, S. D., Chand, N. P., Sanjeev, A., Rajeev, M., Ankur, D., Gopal, S. R., Mzoughi, K., Zairi, I., Jabeur, M., Moussa, F. B., Chaabene, A. B., Kamoun, S., Mrabet, K., Fennira, S., Zargouni, A., Kraiem, S., Demkina, A., Hashieva, F., Krylova, N., Kovalevskaya, E., Potehkina, N., Zaroui, A., Said, R. B., Smaali, S., Rekik, B., Hlima, M. B., Mizouni, H., Mechmeche, R., Mourali, M., Malhotra, A., Sheikh, N., Dhutia, H., Siva, A., Narain, R., Merghani, A., Millar, L., Walker, M., Sharma, S., Papadakis, M., Siam Tsieu, V., Mansencal, N., Arslan, M., Deblaise, J., Dubourg, O., Boudiche, S., Larbi, N., Tababi, N., Hannachi, S., Chalbia, T., Halima, M. B., Boussada, R., Chistyakova, M. V., Govorin, A., Radaeva, E., Lipari, P., Bonapace, S., Valbusa, F., Rossi, A., Zenari, L., Lanzoni, L., Targher, G., Canali, G., Molon, G., Barbieri, E., Novo, G., Giambanco, S., Sutera, M., Bonomo, V., Giambanco, F., Rotolo, A., Evola, S., Assennato, P., Novo, S., Budnik, M., Piatkowski, R., Kochanowski, J., Opolski, G., Chatzistamatiou, E., Vagena, I. M., Manakos, K., Moustakas, G., Konstantinidis, D., Memo, G., Mitsakis, O., Kasakogias, A., Syros, P., Kallikazaros, I., Park, S., Kim, M., Shim, W., Marketou, M., Parthenakis, F., Kalyva, N., Pontikoglou, C., Maragkoudakis, S., Zacharis, E., Patrianakos, A., Maragoudakis, F., Papadaki, H., Vardas, P., Rodrigues, A., Perandini, L. A., Souza, T., Sa Pinto, A., Borba, E., Arruda, A., Furtado, M., Carvalho, F., Bonfa, E., Andrade, J., Hlubocka, Z., Malinova, V., Palecek, T., Danzig, V., Kuchynka, P., Dostalova, G., Zeman, J., Linhart, A., Trachanas, K., Vergi, N., Feretou, A., Corut, H., Sade, L. E., Ozin, B., Atar, I., Turgay, O., Muderrisoglu, H., Ledakowicz Polak, A., Polak, L., Krauza, G., Zielinska, M., Szulik, M., Streb, W., Wozniak, A., Lenarczyk, R., Sliwinska, A., Kalarus, Z., Kukulski, T., Nogueira, M., Branco, L., Agapito, A., Galrinho, A., Borba, A., Teixeira, P., Monteiro, A., Ramos, R., Cacela, D., Ferreira, R. C., Guala, A., Camporeale, C., Tosello, F., Canuto, C., Ridolfi, L., Traxanas, K., Marinov, R., Stamenov, G., Mihova, M., Persenska, S., Racheva, A., Plaskota, K., Trojnarska, O., Bartczak, A., Grajek, S., Bejiqi, R. R., Retkoceri, R., Bejiqi, H., Beha, A., Surdulli, S., Seya, M., Sasaoka, T., Hirasawa, K., Yoshikawa, S., Maejima, Y., Ashikaga, T., Hirao, K., Isobe, M., Dreyfus, J., Durand Viel, G., Cimadevilla, C., Brochet, E., Vahanian, A., Messika Zeitoun, D., Jin, C., Fang, F., Meng, F., Kam, K., Sun, J., Tsui, G., Wong, K., Wan, S., Yu, C., Lee, A., Cho, I. J., Chung, H., Heo, R., Ha, S., Hong, G., Shim, C., Chang, H., Ha, J., Chung, N., Moral, S., Gruosso, D., Galuppo, V., Teixido, G., Rodriguez Palomares, J., Gutierrez, L., Evangelista, A., Alexopoulos, A., Dawson, D., Nihoyannopoulos, P., Zainal, H. A., Ismail, J., Arshad, K., Ibrahim, Z., Lim, C., Rahman, E. A., Kasim, S., Peteiro, J., Barrio, A., Escudero, A., Bouzas Mosquera, A., Yanez, J., Martinez, D., Castro Beiras, A., Scali, M., Simioniuc, A., Mandoli, G., Lombardo, A., Massaro, F., Bello, V. D., Marzilli, M., Dini, F., Adachi, H., Tomono, J., Oshima, S., Ortega, G. M., Bustos, D. B., Garcia, R. L., Espino, A. S., Quinones, J. M., Ikuta, I., Lopez, M. R., Serrano, F. V., Gonzalez, J. B., Recio, M. G., Romano, G., D'Ancona, G., Pilato, G., Gesaro, G. D., Clemenza, F., Raffa, G., Scardulla, C., Sciacca, S., Lancellotti, P., Pilato, M., Addetia, K., Takeuchi, M., Maffessanti, F., Weinert, L., Hamilton, J., Mor Avi, V., Lang, R., Sugano, A., Seo, Y., Watabe, H., Kakefuda, Y., Aihara, H., Nishina, H., Ishizu, T., Fumikura, Y., Noguchi, Y., Aonuma, K., Luo, X., Shang, Q., Sammut, E. C., Chabinok, R., Jackson, T., Siarkos, M., Lee, L., Carr White, G., Rajani, R., Kapetanakis, S., Byrne, D., Walsh, J., Ellis, L., Mckiernan, S., Norris, S., King, G., Murphy, R., Katova, T., Simova, I., Kostova, V., Shuie, I., Ferferieva, V., Bogdanova, V., Castelon, X., Sasi, V., Domsik, P., Kalapos, A., Lengyel, C., Orosz, A., Grapsa, J., Demir, O., Sharma, R., Senior, R., Pilichowska, E., Zaborska, B., Baran, J., Stec, S., Kulakowski, P., Budaj, A., Herrera, J. E., Palacios, I. F., Mendoza, I., Marquez, J. A., Herrera, J. A., Octavio, J. A., Dempaire, G., Rotolo, M., Kosmala, W., Kaye, G., Saito, M., Negishi, K., Maceira, A. M., Ripoll, C., Cosin Sales, J., Igual, B., Salazar, J., Belloch, V., Dulai, R. S., Taylor, A., Gupta, S., and S. U. C., None

Published
2014

19. The great observatories origins deep survey: Initial results from optical and near-infrared imaging

Author

Giavalisco, M, Ferguson, H, Koekemoer, A, Dickinson, M, Alexander, D, Bauer, F, Bergeron, J, Biagetti, C, Brandt, W, Casertano, S, Cesarsky, C, Chatzichristou, E, Conselice, C, Cristiani, S, Da Costa, L, Dahlen, T, De Mello, D, Eisenhardt, P, Erben, T, Fall, S, Fassnacht, C, Fosbury, R, Fruchter, A, Gardner, J, Grogin, N, Hook, R, Hornschemeier, A, Idzi, R, Jogee, S, Kretchmer, C, Laidler, V, Lee, K, Livio, M, Lucas, R, Madau, P, Mobasher, B, Moustakas, L, Nonino, M, Padovani, P, Papovich, C, Park, Y, Ravindranath, S, Renzini, A, Richardson, M, Riess, A, Rosati, P, Schirmer, M, Schreier, E, Somerville, R, Spinrad, H, Stern, D, Stiavelli, M, Strolger, L, Urry, C, Vandame, B, Williams, R, Wolf, C, Giavalisco M., Ferguson H. C., Koekemoer A. M., Dickinson M., Alexander D. M., Bauer F. E., Bergeron J., Biagetti C., Brandt W. N., Casertano S., Cesarsky C., Chatzichristou E., Conselice C., Cristiani S., Da Costa L., Dahlen T., De Mello D., Eisenhardt P., Erben T., Fall S. M., Fassnacht C., Fosbury R., Fruchter A., Gardner J. P., Grogin N., Hook R. N., Hornschemeier A. E., Idzi R., Jogee S., Kretchmer C., Laidler V., Lee K. S., Livio M., Lucas R., Madau P., Mobasher B., Moustakas L. A., Nonino M., Padovani P., Papovich C., Park Y., Ravindranath S., Renzini A., Richardson M., Riess A., Rosati P., Schirmer M., Schreier E., Somerville R. S., Spinrad H., Stern D., Stiavelli M., Strolger L., Urry C. M., Vandame B., Williams R., Wolf C., Giavalisco, M, Ferguson, H, Koekemoer, A, Dickinson, M, Alexander, D, Bauer, F, Bergeron, J, Biagetti, C, Brandt, W, Casertano, S, Cesarsky, C, Chatzichristou, E, Conselice, C, Cristiani, S, Da Costa, L, Dahlen, T, De Mello, D, Eisenhardt, P, Erben, T, Fall, S, Fassnacht, C, Fosbury, R, Fruchter, A, Gardner, J, Grogin, N, Hook, R, Hornschemeier, A, Idzi, R, Jogee, S, Kretchmer, C, Laidler, V, Lee, K, Livio, M, Lucas, R, Madau, P, Mobasher, B, Moustakas, L, Nonino, M, Padovani, P, Papovich, C, Park, Y, Ravindranath, S, Renzini, A, Richardson, M, Riess, A, Rosati, P, Schirmer, M, Schreier, E, Somerville, R, Spinrad, H, Stern, D, Stiavelli, M, Strolger, L, Urry, C, Vandame, B, Williams, R, Wolf, C, Giavalisco M., Ferguson H. C., Koekemoer A. M., Dickinson M., Alexander D. M., Bauer F. E., Bergeron J., Biagetti C., Brandt W. N., Casertano S., Cesarsky C., Chatzichristou E., Conselice C., Cristiani S., Da Costa L., Dahlen T., De Mello D., Eisenhardt P., Erben T., Fall S. M., Fassnacht C., Fosbury R., Fruchter A., Gardner J. P., Grogin N., Hook R. N., Hornschemeier A. E., Idzi R., Jogee S., Kretchmer C., Laidler V., Lee K. S., Livio M., Lucas R., Madau P., Mobasher B., Moustakas L. A., Nonino M., Padovani P., Papovich C., Park Y., Ravindranath S., Renzini A., Richardson M., Riess A., Rosati P., Schirmer M., Schreier E., Somerville R. S., Spinrad H., Stern D., Stiavelli M., Strolger L., Urry C. M., Vandame B., Williams R., and Wolf C.

Abstract

This special issue of the Astrophysical Journal Letters is dedicated to presenting initial results from the Great Observatories Origins Deep Survey (GOODS) that are primarily, but not exclusively, based on multiband imaging data obtained with the Hubble Space Telescope and the Advanced Camera for Surveys (ACS). The survey covers roughly 320 arcmin2 in the ACS F435W, F606W, F814W, and F850LP bands, divided into two well-studied fields. Existing deep observations from the Chandra X-Ray Observatory and ground-based facilities are supplemented with new, deep imaging in the optical and near-infrared from the European Southern Observatory and from the Kitt Peak National Observatory. Deep observations with the Space Infrared Telescope Facility are scheduled. Reduced data from all facilities are being released worldwide within 3-6 months of acquisition. Together, this data set provides two deep reference fields for studies of distant normal and active galaxies, supernovae, and faint stars in our own Galaxy. This Letter serves to outline the survey strategy and describe the specific data that have been used in the accompanying letters, summarizing the reduction procedures and sensitivity limits.

Published
2004

20. Prevalence And Mutational Pattern Of Occult Hepatitis B Virus Isolated From Liver Tissue Of HIV Infected Patients

Author

DE MITRI, MARIA STELLA, CASSINI, ROMINA, Urbinati L., PAVONI, MICHELE, Biagetti C., POCATERRA, DARIA, CALZA, LEONARDO, Ferlini E., BERNARDI, MAURO, CHIODO, FRANCESCO, VERUCCHI, GABRIELLA, De Mitri MS., Cassini R., Urbinati L., Pavoni M., Biagetti C., Pocaterra D., Calza L., Ferlini E., Bernardi M., Chiodo F., and Verucchi G.

Subjects
OCCULT HEPATITIS B, HBV, LIVER TISSUE, HIV
Published
2008

21. Storia e geografia dell'alfabetismo in Grecia. Alle origini di un fenomeno

Author

AMMIRATI, SERENA, BIAGETTI C, RADICIOTTI, PAOLO, Radiciotti, Paolo, Ammirati, Serena, Biagetti, Claudio, and Biagetti, C

Subjects
Literacy, Ancient Greece, Paleography
Abstract

Dopo una introduzione metodologica sugli aspetti quantitativi e qualitativi dell'indagine sull'alfabetismo in Grecia, nonché sul'utilità del criterio geografico nella raccolta e l'analisi dei dati (Radiciotti) si esaminano e discutono, nel contesto della storia degli studi, i materiali epigrafici (Biagetti) e letterari (Ammirati) pertinenti.

Published
2007

33. The first case of congenital lactase deficiency in Italy

Author

Gatti, S., primary, Biagioni, M., additional, Biagetti, C., additional, Romagnoli, V., additional, Pambianchi, M., additional, Carini, C., additional, D’Alba, I., additional, Torniainen, Suvi, additional, Savilahti, Erkki, additional, Järvelä, Irma, additional, and Catassi, C., additional

Published
2008
Full Text
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38. The Great Observatories Origins Deep Survey: Initial Results from Optical and Near-Infrared Imaging

Author

Giavalisco, M., primary, Ferguson, H. C., additional, Koekemoer, A. M., additional, Dickinson, M., additional, Alexander, D. M., additional, Bauer, F. E., additional, Bergeron, J., additional, Biagetti, C., additional, Brandt, W. N., additional, Casertano, S., additional, Cesarsky, C., additional, Chatzichristou, E., additional, Conselice, C., additional, Cristiani, S., additional, Da Costa, L., additional, Dahlen, T., additional, de Mello, D., additional, Eisenhardt, P., additional, Erben, T., additional, Fall, S. M., additional, Fassnacht, C., additional, Fosbury, R., additional, Fruchter, A., additional, Gardner, J. P., additional, Grogin, N., additional, Hook, R. N., additional, Hornschemeier, A. E., additional, Idzi, R., additional, Jogee, S., additional, Kretchmer, C., additional, Laidler, V., additional, Lee, K. S., additional, Livio, M., additional, Lucas, R., additional, Madau, P., additional, Mobasher, B., additional, Moustakas, L. A., additional, Nonino, M., additional, Padovani, P., additional, Papovich, C., additional, Park, Y., additional, Ravindranath, S., additional, Renzini, A., additional, Richardson, M., additional, Riess, A., additional, Rosati, P., additional, Schirmer, M., additional, Schreier, E., additional, Somerville, R. S., additional, Spinrad, H., additional, Stern, D., additional, Stiavelli, M., additional, Strolger, L., additional, Urry, C. M., additional, Vandame, B., additional, Williams, R., additional, and Wolf, C., additional

Published
2004
Full Text
View/download PDF

39. The On-Orbit Performance of the Space Telescope Imaging Spectrograph

Author

Kimble, R. A., primary, Woodgate, B. E., additional, Bowers, C. W., additional, Kraemer, S. B., additional, Kaiser, M. E., additional, Gull, T. R., additional, Heap, S. R., additional, Danks, A. C., additional, Boggess, A., additional, Green, R. F., additional, Hutchings, J. B., additional, Jenkins, E. B., additional, Joseph, C. L., additional, Linsky, J. L., additional, Maran, S. P., additional, Moos, H. W., additional, Roesler, F., additional, Timothy, J. G., additional, Weistrop, D. E., additional, Grady, J. F., additional, Loiacono, J. J., additional, Brown, L. W., additional, Brumfield, M. D., additional, Content, D. A., additional, Feinberg, L. D., additional, Isaacs, M. N., additional, Krebs, C. A., additional, Krueger, V. L., additional, Melcher, R. W., additional, Rebar, F. J., additional, Vitagliano, H. D., additional, Yagelowich, J. J., additional, Meyer, W. W., additional, Hood, D. F., additional, Argabright, V. S., additional, Becker, S. I., additional, Bottema, M., additional, Breyer, R. R., additional, Bybee, R. L., additional, Christon, P. R., additional, Delamere, A. W., additional, Dorn, D. A., additional, Downey, S., additional, Driggers, P. A., additional, Ebbets, D. C., additional, Gallegos, J. S., additional, Garner, H., additional, Hetlinger, J. C., additional, Lettieri, R. L., additional, Ludtke, C. W., additional, Michika, D., additional, Nyquist, R., additional, Rose, D. M., additional, Stocker, R. B., additional, Sullivan, J. F., additional, Van Houten, C. N., additional, Woodruff, R. A., additional, Baum, S. A., additional, Hartig, G. F., additional, Balzano, V., additional, Biagetti, C., additional, Blades, J. C., additional, Bohlin, R. C., additional, Clampin, M., additional, Doxsey, R., additional, Ferguson, H. C., additional, Goudfrooij, P., additional, Hulbert, S. J., additional, Kutina, R., additional, McGrath, M., additional, Lindler, D. J., additional, Beck, T. L., additional, Feggans, J. K., additional, Plait, P. C., additional, Sandoval, J. L., additional, Hill, R. S., additional, Collins, N. R., additional, Cornett, R. H., additional, Fowler, W. B., additional, Hill, R. J., additional, Landsman, W. B., additional, Malumuth, E. M., additional, Standley, C., additional, Blouke, M., additional, Grusczak, A., additional, Reed, R., additional, Robinson, R. D., additional, Valenti, J. A., additional, and Wolfe, T., additional

Published
1998
Full Text
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41. Low avidity antibody: A reliable method to diagnose a recent HIV-1 infection

Author

Maria Carla Re, Schiavone P, Vitone F, Bon I, De Crignis E, Biagetti C, Alessandrini F, Gibellini D, Re MC., Schiavone P., Vitone F., Bon I., De Crignis E., Biagetti C., Alessandrini F., and Gibellini D.

Subjects
Adult, Male, Avidity index, Antibody Affinity, HIV, Acute infection, HIV Infections, HIV Antibodies, Middle Aged, DIAGNOSIS METHODS, Acute Disease, HIV Seropositivity, HIV-1, Humans, AVIDITY, HIV-1, Acute infection, Avidity index, Female
Abstract

Standard serological tests (both EIA and Immunoblotting) have reached high levels of sensitivity and reproducibility, but do not indicate whether infection is recent or longstanding. Since many patients with HIV-1 infection are not usually diagnosed until symptom presentation, the possibility to distinguish between acute and chronic infection has become increasingly important for the purposes of therapeutic decision-making, partner notification and epidemiological surveillance. We evaluated a guanidine-based-antibody-avidity assay in a selected group of recent (within six months from seroconversion) and chronic (more than forty eight months) HIV-1 infections in an attempt to shed more light on the significance of the avidity index in establishing the time of infection. Sera from newly infected individuals showed a low mean avidity index (ranging from 0.35 to 0.60 with a standard deviation 0.09) at baseline and a clear increasing value at the following times of observation. Our data showed that an avidity index

42. VizieR Online Data Catalog: GOODS initial results (Giavalisco+, 2004)

Author

Giavalisco, M., Ferguson, H. C., Koekemoer, A. M., Dickinson, M., Alexander, D. M., Bauer, F. E., Bergeron, J., Biagetti, C., Brandt, W. N., Casertano, S., Cesarsky, C., Chatzichristou, E., Conselice, C., Cristiani, S., Da Costa, L., Dahlen, T., Mello, D., Eisenhardt, P., Erben, T., Fall, S. M., Fassnacht, C., Fosbury, R., Fruchter, A., Gardner, J. P., Grogin, N., Hook, R. N., Hornschemeier, A. E., Idzi, R., Jogee, S., Kretchmer, C., Laidler, V., Lee, K. S., Livio, M., Lucas, R., Madau, P., Mobasher, B., Moustakas, L. A., Nonino, M., Padovani, P., Papovich, C., Park, Y., Ravindranath, S., Renzini, A., Richardson, M., Riess, A., Rosati, P., Schirmer, M., Schreier, E., Somerville, R. S., Spinrad, H., Stern, D., Stiavelli, M., Strolger, L., Meg Urry, Vandame, B., Williams, R., and Wolf, C.

43. Poster session 1: Wednesday 3 December 2014, 09:00-16:00 * Location: Poster area

Author

Tong, L, Huang, C, Ramalli, A, Tortoli, P, Luo, J, D'hooge, J, Tzemos, N, Mordi, I, Bishay, T, Bishay, T, Negishi, T, Hristova, K, Kurosawa, K, Bansal, M, Thavendiranathan, P, Yuda, S, Popescu, BA, Vinereanu, D, Penicka, M, Marwick, TH, study, SUCCOUR, Hamed, W, Kamel, MKA, Yaseen, RIY, El-Barbary, HSE, Nemes, A, Kis, O, Gavaller, H, Kanyo, E, Forster, T, Angelis, A, Vlachopoulos, C, Ioakimidis, N, Felekos, I, Chrysohoou, C, Aznaouridis, K, Abdelrasoul, M, Terentes, D, Ageli, K, Stefanadis, C, Kurnicka, K, Domienik-Karlowicz, J, Lichodziejewska, B, Goliszek, S, Grudzka, K, Krupa, M, Dzikowska-Diduch, O, Ciurzynski, M, Pruszczyk, P, Gual Capllonch, F, Lopez Ayerbe, J, Teis, A, Ferrer, E, Vallejo, N, Junca, G, Pla, R, Bayes-Genis, A, Schwaiger, JP, Knight, DS, Gallimore, A, Schreiber, BE, Handler, C, Coghlan, JG, Bruno, R M, Giardini, G, Malacrida, S, Catuzzo, B, Armenia, S, Brustia, R, Ghiadoni, L, Cauchy, E, Pratali, L, Kim, KH, Lee, KJ, Cho, JY, Yoon, HJ, Ahn, Y, Jeong, MH, Cho, JG, Park, JC, Cho, SK, Nastase, O, Enache, R, Mateescu, AD, Botezatu, D, Popescu, BA, Ginghina, C, Gu, H, Sinha, MD, Simpson, JM, Chowienczyk, PJ, Fazlinezhad, A, Tashakori Behesthi, AHMAD, Homaei, FATEME, Mostafavi, H, Hosseini, G, Bakaeiyan, M, Boutsikou, M, Petrou, E, Dimopoulos, A, Dritsas, A, Leontiadis, E, Karatasakis, G, Sahin, S T, Yurdakul, S, Yilmaz, N, Cengiz, B, Cagatay, Y, Aytekin, S, Yavuz, S, Karlsen, S, Dahlslett, T, Grenne, B, Sjoli, B, Smiseth, OA, Edvardsen, T, Brunvand, H, Nasr, G, Nasr, A, Eleraki, A, Elrefai, S, Mordi, I, Sonecki, P, Tzemos, N, Gustafsson, U, Naar, J, Stahlberg, M, Cerne, A, Capotosto, L, Rosato, E, D'angeli, I, Azzano, A, Truscelli, G, De Maio, M, Salsano, F, Terzano, C, Mangieri, E, Vitarelli, A, Renard, S, Najih, H, Mancini, J, Jacquier, A, Haentjens, J, Gaubert, JY, Habib, G, Caminiti, G, D'antoni, V, D'antoni, V, Cardaci, V, Cardaci, V, Conti, V, Conti, V, Volterrani, M, Volterrani, M, Ahn, J, Kim, DH, Lee, HO, Iliuta, L, Kim, SY, Ryu, S, Ko, CW, Pyun, YS, Yoon, SJ, Lo Iudice, F, Esposito, R, Lembo, M, Santoro, C, Ballo, PC, Mondillo, S, De Simone, G, Galderisi, M, Hwang, YM, Kim, JH, Kim, JH, Moon, KW, Yoo, KD, Kim, CM, Tagliamonte, E, Rigo, F, Cirillo, T, Caruso, A, Astarita, C, Cice, G, Quaranta, G, Romano, C, Capuano, N, Calabro', R, Zagatina, A, Zhuravskaya, N, Guseva, O, Huttin, O, Benichou, M, Voilliot, D, Venner, C, Micard, E, Girerd, N, Sadoul, N, Moulin, F, Juilliere, Y, Selton-Suty, C, Baron, T, Christersson, C, Johansson, K, Flachskampf, FA, Lee, S, Lee, J, Hur, S, Park, J, Yun, JY, Song, SK, Kim, WH, Ko, JK, Nyktari, E, Bilal, S, Ali, SA, Izgi, C, Prasad, SK, Aly, MFA, Kleijn, SAK, Kandil, HIK, Kamp, OK, Beladan, CC, Calin, A, Rosca, M, Craciun, AM, Gurzun, MM, Calin, C, Enache, R, Mateescu, A, Ginghina, C, Popescu, BA, Mornos, C, Mornos, A, Ionac, A, Cozma, D, Crisan, S, Popescu, I, Ionescu, G, Petrescu, L, Camacho, S, Gamaza Chulian, S, Carmona, R, Diaz, E, Giraldez, A, Gutierrez, A, Toro, R, Benezet, J, Antonini-Canterin, F, Vriz, O, La Carrubba, S, Poli, S, Leiballi, E, Zito, C, Careri, S, Caruso, R, Pellegrinet, M, Nicolosi, GL, Kong, W, Kyu, K, Wong, R, Tay, E, Yip, J, Yeo, TC, Poh, KK, Correia, M, Delgado, A, Marmelo, B, Correia, E, Abreu, L, Cabral, C, Gama, P, Santos, O, Rahman, MT, Borges, I P, Peixoto, ECS, Peixoto, RTS, Peixoto, RTS, Marcolla, VF, Okura, H, Kanai, M, Murata, E, Kataoka, T, Stoebe, S, Tarr, A, Pfeiffer, D, Hagendorff, A, Generati, G, Bandera, F, Pellegrino, M, Alfonzetti, E, Labate, V, Guazzi, M, Kuznetsov, VA, Yaroslavskaya, EI, Pushkarev, GS, Krinochkin, DV, Zyrianov, IP, Carigi, S, Baldazzi, F, Bologna, F, Amati, S, Venturi, P, Grosseto, D, Biagetti, C, Fabbri, E, Arlotti, M, Piovaccari, G, Rahbi, H, Bin Abdulhaq, A, Tleyjeh, I, Santoro, C, Galderisi, M, Costantino, MF, Tarsia, G, Innelli, P, Dores, E, Esposito, G, Matera, A, De Simone, G, Trimarco, B, Capotosto, L, Azzano, A, Mukred, K, Ashurov, R, Tanzilli, G, Mangieri, E, Vitarelli, A, Merlo, M, Gigli, M, Stolfo, D, Pinamonti, B, Antonini Canterin, F, Muca, M, D'angelo, GA, Scapol, S, Di Nucci, M, Sinagra, G, Behaghel, A, Feneon, D, Fournet, M, Thebault, C, Martins, RP, Mabo, P, Leclercq, C, Daubert, C, Donal, E, Davinder Pal, SINGH, Prakash Chand, NEGI, Sanjeev, ASOTRA, Rajeev, MERWAH, Ankur, DWIVED, Ram Gopal, SOOD, Mzoughi, K, Zairi, I, Jabeur, M, Ben Moussa, F, Ben Chaabene, A, Kamoun, S, Mrabet, K, Fennira, S, Zargouni, A, Kraiem, S, Demkina, AE, Hashieva, FM, Krylova, NS, Kovalevskaya, EA, Potehkina, NG, Zaroui, A, Ben Said, R, Smaali, S, Rekik, B, Ben Hlima, M, Mizouni, H, Mechmeche, R, Mourali, MS, Malhotra, A, Sheikh, N, Dhutia, H, Siva, A, Narain, R, Merghani, A, Millar, L, Walker, M, Sharma, S, Papadakis, M, Siam-Tsieu, V, Mansencal, N, Arslan, M, Deblaise, J, Dubourg, O, Zaroui, A, Rekik, B, Ben Said, R, Boudiche, S, Larbi, N, Tababi, N, Hannachi, S, Mechmeche, R, Mourali, MS, Mechmeche, R, Zaroui, A, Chalbia, T, Ben Halima, M, Rekik, B, Boussada, R, Mourali, MS, Chistyakova, M V, Govorin, AV, Radaeva, EV, Lipari, P, Bonapace, S, Valbusa, F, Rossi, A, Zenari, L, Lanzoni, L, Targher, G, Canali, G, Molon, G, Barbieri, E, Novo, G, Giambanco, S, Sutera, MR, Bonomo, V, Giambanco, F, Rotolo, A, Evola, S, Assennato, P, Novo, S, Budnik, M, Piatkowski, R, Kochanowski, J, Opolski, G, Chatzistamatiou, E, Mpampatseva Vagena, I, Manakos, K, Moustakas, G, Konstantinidis, D, Memo, G, Mitsakis, O, Kasakogias, A, Syros, P, Kallikazaros, I, Park, SM, Kim, SA, Kim, MN, Shim, WJ, Marketou, M, Parthenakis, F, Kalyva, N, Pontikoglou, CH, Maragkoudakis, S, Zacharis, E, Patrianakos, A, Maragoudakis, F, Papadaki, H, Vardas, P, Rodrigues, AC, Perandini, LA, Souza, TR, Sa-Pinto, AL, Borba, E, Arruda, AL, Furtado, M, Carvalho, F, Bonfa, E, Andrade, JL, Hlubocka, Z, Malinova, V, Palecek, T, Danzig, V, Kuchynka, P, Dostalova, G, Zeman, J, Linhart, A, Chatzistamatiou, E, Konstantinidis, D, Memo, G, Mpampatzeva Vagena, I, Moustakas, G, Manakos, K, Trachanas, K, Vergi, N, Feretou, A, Kallikazaros, I, Corut, H, Sade, LE, Ozin, B, Atar, I, Turgay, O, Muderrisoglu, H, Ledakowicz-Polak, A, Polak, L, Krauza, G, Zielinska, M, Szulik, M, Streb, W, Wozniak, A, Lenarczyk, R, Sliwinska, A, Kalarus, Z, Kukulski, T, Nogueira, MA, Branco, LM, Agapito, A, Galrinho, A, Borba, A, Teixeira, PP, Monteiro, AV, Ramos, R, Cacela, D, Cruz Ferreira, R, Guala, A, Camporeale, C, Tosello, F, Canuto, C, Ridolfi, L, Chatzistamatiou, E, Moustakas, G, Memo, G, Konstantinidis, D, Mpampatzeva Vagena, I, Manakos, K, Traxanas, K, Vergi, N, Feretou, A, Kallikazaros, I, Hristova, K, Marinov, R, Stamenov, G, Mihova, M, Persenska, S, Racheva, A, Plaskota, KJ, Trojnarska, O, Bartczak, A, Grajek, S, Ramush Bejiqi, RA, Retkoceri, R, Bejiqi, H, Beha, A, Surdulli, SH, Seya, M, Sasaoka, T, Hirasawa, K, Yoshikawa, S, Maejima, Y, Ashikaga, T, Hirao, K, Isobe, M, none, Dreyfus, J, Durand-Viel, G, Cimadevilla, C, Brochet, E, Vahanian, A, Messika-Zeitoun, D, Jin, CN, Fang, F, Meng, FX, Kam, K, Sun, JP, Tsui, GK, Wong, KK, Wan, S, Yu, CM, Lee, AP, Cho, I J, Chung, HM, Heo, R, Ha, SJ, Hong, GR, Shim, CY, Chang, HJ, Ha, JW, Chung, N, Moral, S, Gruosso, D, Galuppo, V, Teixido, G, Rodriguez-Palomares, JF, Gutierrez, L, Evangelista, A, Moral, S, Gruosso, D, Galuppo, V, Teixido, G, Rodriguez-Palomares, JF, Gutierrez, L, Evangelista, A, Moral, S, Gruosso, D, Galuppo, V, Teixido, G, Rodriguez-Palomares, JF, Gutierrez, L, Evangelista, A, Alexopoulos, Alexan, Dawson, David, Nihoyannopoulos, Petros, Zainal Abidin, H A, Ismail, JOHAN, Arshad, KAMAL, Ibrahim, ZUBIN, Lim, CW, Abd Rahman, E, Kasim, SAZZLI, Peteiro, J, Barrio, A, Escudero, A, Bouzas-Mosquera, A, Yanez, J, Martinez, D, Castro-Beiras, A, Scali, MC, Simioniuc, A, Mandoli, GE, Lombardo, A, Massaro, F, Di Bello, V, Marzilli, M, Dini, FL, Adachi, H, Tomono, J, Oshima, S, Merchan Ortega, G, Bravo Bustos, D, Lazaro Garcia, R, Sanchez Espino, AD, Macancela Quinones, JJ, Ikuta, I, Ruiz Lopez, MF, Valencia Serrano, FM, Bonaque Gonzalez, JC, Gomez Recio, M, Romano, G, D'ancona, G, Pilato, G, Di Gesaro, G, Clemenza, F, Raffa, G, Scardulla, C, Sciacca, S, Lancellotti, P, Pilato, M, Addetia, K, Takeuchi, M, Maffessanti, F, Weinert, L, Hamilton, J, Mor-Avi, V, Lang, RM, Sugano, A, Seo, Y, Watabe, H, Kakefuda, Y, Aihara, H, Nishina, H, Ishizu, T, Fumikura, Y, Noguchi, Y, Aonuma, K, Luo, XX, Fang, F, Lee, APW, Shang, Q, Yu, CM, Sammut, E C, Chabinok, R, Jackson, T, Siarkos, M, Lee, L, Carr-White, G, Rajani, R, Kapetanakis, S, Byrne, D, Walsh, JP, Ellis, L, Mckiernan, S, Norris, S, King, G, Murphy, RT, Hristova, K, Katova, TZ, Simova, I, Kostova, V, Shuie, I, Ferferieva, V, Bogdanova, V, Castelon, X, Nemes, A, Sasi, V, Domsik, P, Kalapos, A, Lengyel, C, Orosz, A, Forster, T, Grapsa, J, Demir, O, Dawson, D, Sharma, R, Senior, R, Nihoyannopoulos, P, Pilichowska, E, Zaborska, B, Baran, J, Stec, S, Kulakowski, P, Budaj, A, Herrera, J E, Palacios, I F, Mendoza, I, Marquez, J A, Herrera, J A, Octavio, J A, Dempaire, G, Rotolo, M, Kosmala, W, Kaye, G, Saito, M, Negishi, K, Marwick, TH, Maceira Gonzalez, A M, Ripoll, C, Cosin-Sales, J, Igual, B, Salazar, J, Belloch, V, Dulai, R S, Taylor, A, and Gupta, S

Abstract

Purpose: We have previously demonstrated that multi-line transmit (MLT) beam forming can provide high quality full field-of-view (90° sector) B-mode images at very high frame rates, i.e. up to 500 fps. The purpose of this study was to test the feasibility of this technique in imaging the mechanical intraventricular waves such as the one associated with activation of the left ventricle. Methods: A dedicated pulse sequence using MLT was implemented on the ULA-OP research scanner equipped with a 2.0 MHz phased array to obtain 90° sector images at a frame rate of 436 fps. The left ventricle of a healthy volunteer was imaged from the apical 4 chamber view and the RF data was acquired. Subsequently, the strain rate was extracted from the RF data using a normalized cross-correlation method. Results: As expected, during the early filling phase, myocardium lengthening (positive strain rate) was observed propagating from the base of the septum to the apex and back (Figure a). A similar wave was detected in the lateral wall, although a brief shortening (negative strain rate) was detected in the mid-wall which could be the result of reverberations (Figure b). During isovolumetric contraction, the septal wall shortened before the lateral wall (as expected) - moreover - there seemed to be an intra-wall base-apex shortening gradient (Figure c and d). Conclusions: Our preliminary results show that visualization of the cardiac mechanical activation could be feasible using MLT based high frame rate imaging. Further research is required to examine this in depth, which is the topic of on-going work. Figure Curved M-mode of strain rate

Published
2014
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45. Reduction trend of mcr-1 circulation in Emilia-Romagna Region, Italy

Author

Simone Ambretti, Chiara Bracchi, Vittorio Sambri, Carlo Biagetti, Adriana Calderaro, Claudia Venturelli, Giuseppe Diegoli, Ilaria Menozzi, Maria Federica Pedna, Martina Tambassi, Rossella Buttazzi, Carlo Gagliotti, Stefano Pongolini, Mario Sarti, Enrico Ricchizzi, Marianna Meschiari, Maria Luisa Moro, Erika Scaltriti, Massimo Confalonieri, Agostino Barozzi, Marina Morganti, Laura Soliani, Roberta Schiavo, Edoardo Carretto, Luca Bolzoni, Fabio Tumietto, Chiara Casadio, Gagliotti C., Bolzoni L., Carretto E., Sarti M., Ricchizzi E., Ambretti S., Barozzi A., Bracchi C., Confalonieri M., Menozzi I., Morganti M., Pedna M.F., Sambri V., Scaltriti E., Schiavo R., Soliani L., Tambassi M., Venturelli C., Biagetti C., Buttazzi R., Calderaro A., Casadio C., Meschiari M., Tumietto F., Diegoli G., Pongolini S., and Moro M.L.

Subjects
Microbiology (medical), Veterinary medicine, Antimicrobials for veterinary use, Antibiotic resistance, Clonal dissemination, Klebsiella pneumoniae, Population, Drug Resistance, Horizontal transfer, Bacterial Protein, Microbial Sensitivity Tests, Minimum inhibitory concentration, Enterobacterales, One Health approach, Plasmid, Bacterial Proteins, Enterobacteriaceae, Enterobacterale, Anti-Bacterial Agent, Drug Resistance, Bacterial, medicine, Humans, Colistin, Mcr, Anti-Bacterial Agents, Enterobacteriaceae Infections, Ethanolaminephosphotransferase, Italy, Phylogeny, Retrospective Studies, education, education.field_of_study, biology, Microbial Sensitivity Test, Bacterial, General Medicine, biology.organism_classification, Enterobacteriaceae Infection, Infectious Diseases, Salmonella enterica, MCR-1, Enterobacter cloacae, hormones, hormone substitutes, and hormone antagonists, Human, medicine.drug
Abstract

This study aims to describe trends of mcr-positive Enterobacterales in humans based on laboratory surveillance with a defined catchment population. The data source is the Micro-RER surveillance system, established in Emilia-Romagna region (Italy), to monitor the trend of mcr resistance. Enterobacterales isolates from human clinical samples with minimum inhibitory concentration (MIC) ≥ 2mg/L for colistin were sent to the study reference laboratory for the detection of mcr genes. Isolates prospectively collected in the period 2018–2020 were considered for the assessment of population rates and trends; further analyses were carried out for the evaluation of clonality and horizontal mcr gene transfer. Previous isolates from local laboratory collection were also described. In the period 2018–2020, 1164 isolates were sent to the reference laboratory, and 51 (4.4%) were confirmed as mcr-positive: 50 mcr-1 (42 Escherichia coli, 6 Klebsiella pneumoniae, 2 Salmonella enterica) and 1 mcr-4 (Enterobacter cloacae). The number of mcr-positive isolates dropped from 24 in the first half of 2018 to 3 in the whole of 2020 (trend p value < 0.001). Genomic analyses showed the predominant role of the horizontal transfer of mcr genes through plasmids or dissemination of transposable elements compared to clonal dissemination of mcr-positive microorganisms. The study results demonstrate a substantial decrease in the circulation of mcr-1 plasmid genes in Emilia-Romagna Region.

Published
2021
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46. Procedimenti giuridici e sanzione religiosa nel mondo greco e romano: un excursus tematico

Author

BONANNO, Daniela, Funke, P, Haake, M., Bonanno, D, Funke, P., Haake, M., Bonanno, D., Funke P., Cusumano, N, Drauschke M, Knaepper, K, Gallo A, Stratmann, L, Ingarao, G., Scharff, S, Aletsee, A-S, Lepke, A, Terrinoni, A, Liebs, D, Kuhn, E, Haake, M, Zimmermann, K, Biagetti, C, Buongiorno P, Saggioro, A, Mecella, L, Ferri G, Motta, D., Filippini, A, and Funke, P

Subjects
Settore L-ANT/02 - Storia Greca, Settore L-ANT/03 - Storia Romana, Diritto, religione, società, Grecia, Roma
Abstract

Il saggio propone uno status quaestionis e un'introduzione ai saggi raccolti nel volume "Rechtliche Verfahren und religiöse Sanktionierung in der griechisch-römischen Antike /Procedimenti giuridici e sanzione religiosa nel mondo greco e romano".

Published
2016

47. Incomplete IgG response to HIV-1 proteins and low avidity levels in recently converted HIV patients treated with early antiretroviral therapy

Author

Davide Gibellini, Pasqua Schiavone, Carlo Biagetti, Elisa De Crignis, Isabella Bon, Francesca Vitone, Maria Carla Re, Re MC, Schiavone P, Bon I, Vitone F, De Crignis E, Biagetti C, and Gibellini D.

Subjects
Microbiology (medical), Adult, Male, HAART, Blotting, Western, Antibody Affinity, Gene Products, gag, HIV Infections, Western blot, HIV Antibodies, Virus Replication, DIAGNOSIS, Immunoglobulin G, Group B, Nucleoside Reverse Transcriptase Inhibitor, Immune system, ANTIRETROVIRAL THERAPY, Antiretroviral Therapy, Highly Active, HIV Seropositivity, medicine, Humans, Avidity, Longitudinal Studies, Seroconversion, Retrospective Studies, Primary HIV-1 infection, Antibody avidity, Reverse-transcriptase inhibitor, medicine.diagnostic_test, biology, business.industry, virus diseases, HIV, General Medicine, Virology, Infectious Diseases, pol Gene Products, Human Immunodeficiency Virus, Immunology, biology.protein, HIV-1, RNA, Viral, Female, business, medicine.drug, Follow-Up Studies
Abstract

Summary Objectives To evaluate the evolution of antibody avidity and Western blot reactivity in recently infected HIV-1 subjects and to study the impact of highly active antiretroviral therapy (HAART) on avidity maturation of HIV-1-specific immunoglobulin G (IgG) in patients with recent HIV-1 infection. Methods Thirty-six HIV-1 seroconverters were enrolled in this study and followed longitudinally over 24 months to evaluate if the administration of antiretroviral therapy during primary infection affects Western blot reactivity and the evolution of antibody avidity. The patients were divided into two groups; group A consisted of 19 HIV-1-untreated patients who did not receive any drug treatment during our follow-up period; group B consisted of 17 subjects who were treated early with an association of two nucleoside reverse transcriptase inhibitors (NRTI) and one non-nucleoside reverse transcriptase inhibitor (NNRTI) within 3 months after seroconversion. Results At diagnosis, Western blot analysis and avidity index (mean value) were exactly matched in untreated and treated patients; subsequently, however, a significantly lower reactivity to HIV-1 pol and gag proteins and a lower avidity index (mean values) were observed in HAART-treated patients up until the end of the follow-up period. Conclusions The impaired production and maturation of the humoral immunological response in antiretroviral-treated patients might be related to a rapid suppression of HIV replication, driven by HAART. These results could have important implications in understanding the complex mechanism of the immune response during HIV infection.

Published
2010

48. HIV-1 subtype C transmission network: The phylogenetic reconstruction strongly supports the epidemiological data

Author

Davide Gibellini, Isabella Bon, Alessia Lai, Gianni Zehender, Carlo Biagetti, Massimo Ciccozzi, Alessandra Lo Presti, Maria Carla Re, Gabriella Verrucchi, Bon I, Ciccozzi M, Zehender G, Biagetti C, Verucchi G, Lai A, Lo Presti A, Gibellini D, and Re MC

Subjects
medicine.medical_specialty, Genotype, Human immunodeficiency virus (HIV), HIV Infections, Biology, medicine.disease_cause, law.invention, Genetic, Phylogenetics, law, Virology, Epidemiology, medicine, Cluster Analysis, Humans, pol Gene Products, Polymorphism, Phylogeny, Genetics, Molecular Epidemiology, Polymorphism, Genetic, Molecular epidemiology, Infant, Newborn, Infant, DNA, Sequence Analysis, DNA, Newborn, Infant newborn, Phylogenetic reconstruction, Infectious Diseases, Transmission (mechanics), Female, HIV-1, pol Gene Products, Human Immunodeficiency Virus, Evolutionary biology, Transmission network, Sequence Analysis, Human Immunodeficiency Virus
Abstract

The sequence and times of the transmission events was reported after a hospital accident by a phylodynamic reconstruction of transmission network among four subjects. The dated tree allowed to date the transmission events with good approximation, the time point and direction of each transmission, estimated on the basis of the phylogeny, and agreed with the presumptive time of infection on the basis of clinical history-taking.

Published
2010

49. Metabolic bone disease in HIV infection

Author

Carlo Biagetti, Livia Tampellini, Laura Cimatti, Marco Borderi, Fabio Vescini, Davide Gibellini, Maria Carla Re, Elisa De Crignis, Borderi M., Gibellini D., Vescini F., De Crignis E., Cimatti L., Biagetti C., Tampellini L., and Re MC.

Subjects
HAART, business.industry, bone, HIV, osteoblasts, osteoclasts, Immunology, Osteoporosis, Disease, medicine.disease, Metabolic bone disease, Osteopenia, Pathogenesis, Infectious Diseases, Acquired immunodeficiency syndrome (AIDS), Immunopathology, Immunology and Allergy, Medicine, Viral disease, business
Abstract

HIV mainly replicates in CD4þ T lymphocytes andmonocyte/macrophages causing severe immunologicalimpairment. In addition to the immune system, HIVinfection affects tissues and organs such as kidney, liver,the central nervous system, heart and bone showing acomplex pathogenesis [1].The advent and widespread use of highly activeantiretroviral therapy (HAART) in the last two decadeshasled toa markedimprovementinthe treatmentofHIVdisease even though viral infection cannot be eradicatedbecause HAART does not completely eliminate the viralreservoirs [2]. HAART has dramatically changed thecourseofHIVinfection froma fatalinfectiontoachronicand relatively manageable disease. The increased lifeexpectancyofHIVpatientsandtheeffectsofHAARThavechanged the management of HIV infection. Nowadaysmedical treatment is no longer focused solely on HIVinfection, opportunistic diseases and monitoring immunederangement, but also includes the control of metabolic,cardiovascular, liver, bone and kidney complications. Inparticular, bone alterations have been observed in thecourse of HIV disease representing a pivotal clinicalprobleminthemanagementofHIVpatientsespeciallyforapossible development of bone fractures [3]. The majorbonelesionsdetectableinHIVpatientsarerelatedtobonedemineralization (osteopenia/osteoporosis and osteoma-lacia) and osteonecrosis ([4] for a review).This report will discuss the pathogenesis, diagnosis andtreatment of major bone complications represented bybone demineralization diseases during HIV infection andHAART treatment.

Published
2009

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