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1,337 results on '"Bhushan, Shashi"'

7. AI Coach Assist: An Automated Approach for Call Recommendation in Contact Centers for Agent Coaching

Author

Laskar, Md Tahmid Rahman, Chen, Cheng, Fu, Xue-Yong, Azizi, Mahsa, Bhushan, Shashi, and Corston-Oliver, Simon

Subjects
Computer Science - Computation and Language, Computer Science - Artificial Intelligence, Computer Science - Machine Learning
Abstract

In recent years, the utilization of Artificial Intelligence (AI) in the contact center industry is on the rise. One area where AI can have a significant impact is in the coaching of contact center agents. By analyzing call transcripts using Natural Language Processing (NLP) techniques, it would be possible to quickly determine which calls are most relevant for coaching purposes. In this paper, we present AI Coach Assist, which leverages the pre-trained transformer-based language models to determine whether a given call is coachable or not based on the quality assurance (QA) questions asked by the contact center managers or supervisors. The system was trained and evaluated on a large dataset collected from real-world contact centers and provides an effective way to recommend calls to the contact center managers that are more likely to contain coachable moments. Our experimental findings demonstrate the potential of AI Coach Assist to improve the coaching process, resulting in enhancing the performance of contact center agents., Comment: ACL 2023 Industry Track

Published
2023

14. A Modified Honey Badger Algorithm with Logistic Map and Enhanced Exploitation

Author

Rajpurohit, Jitendra, Sharma, Tarun Kumar, Bhushan, Shashi, Sharma, Abhay, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Kumar, Rajesh, editor, Verma, Ajit Kumar, editor, Verma, Om Prakash, editor, and Wadehra, Tanu, editor

Published
2024
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15. Deep Learning-Based Summarized Notes Generation from Document

Author

Kumari, Lalita, Bhushan, Shashi, Dixit, Santosh, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Singh, Yashwant, editor, Singh, Pradeep Kumar, editor, Gonçalves, Paulo J. Sequeira, editor, and Kar, Arpan Kumar, editor

Published
2024
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29. Rearrangement of a unique Kv1.3 selectivity filter conformation upon binding of a drug

Author

Tyagi, Anu, Ahmed, Tofayel, Jian, Shi, Bajaj, Saumya, Ong, Seow Theng, Goay, Stephanie Shee Min, Zhao, Yue, Vorobyov, Igor, Tian, Changlin, Chandy, K George, and Bhushan, Shashi

Subjects
Inorganic Chemistry, Chemical Sciences, Amino Acid Sequence, Binding Sites, Humans, Ion Channel Gating, Kv1.3 Potassium Channel, Membrane Potentials, Microscopy, Electron, Models, Molecular, Molecular Conformation, Potassium, Potassium Channels, Potassium Channels, Voltage-Gated, Sequence Alignment, ion channels, potassium channels, selectivity filter, ShK, dalazatide
Abstract

We report two structures of the human voltage-gated potassium channel (Kv) Kv1.3 in immune cells alone (apo-Kv1.3) and bound to an immunomodulatory drug called dalazatide (dalazatide-Kv1.3). Both the apo-Kv1.3 and dalazatide-Kv1.3 structures are in an activated state based on their depolarized voltage sensor and open inner gate. In apo-Kv1.3, the aromatic residue in the signature sequence (Y447) adopts a position that diverges 11 Å from other K+ channels. The outer pore is significantly rearranged, causing widening of the selectivity filter and perturbation of ion binding within the filter. This conformation is stabilized by a network of intrasubunit hydrogen bonds. In dalazatide-Kv1.3, binding of dalazatide to the channel's outer vestibule narrows the selectivity filter, Y447 occupies a position seen in other K+ channels, and this conformation is stabilized by a network of intersubunit hydrogen bonds. These remarkable rearrangements in the selectivity filter underlie Kv1.3's transition into the drug-blocked state.

Published
2022

33. Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels.

Author

Ong, Seow, Tyagi, Anu, Chandy, K, and Bhushan, Shashi

Subjects
C-type inactivation, Kv1.3, Shaker-IR, cryo-EM, dalazatide, hydrogen bond network, slow inactivation, voltage-gated potassium (Kv) channels
Abstract

Voltage-gated potassium (Kv) channels modulate the function of electrically-excitable and non-excitable cells by using several types of gates to regulate ion flow through the channels. An important gating mechanism, C-type inactivation, limits ion flow by transitioning Kv channels into a non-conducting inactivated state. Here, we highlight two recent papers, one on the human Kv1.3 channel and the second on the Drosophila Shaker Kv channel, that combined cryogenic electron microscopy and molecular dynamics simulation to define mechanisms underlying C-type inactivation. In both channels, the transition to the non-conducting inactivated conformation begins with the rupture of an intra-subunit hydrogen bond that fastens the selectivity filter to the pore helix. The freed filter swings outwards and gets tethered to an external residue. As a result, the extracellular end of the selectivity filter dilates and K+ permeation through the pore is impaired. Recovery from inactivation may entail a reversal of this process. Such a reversal, at least partially, is induced by the peptide dalazatide. Binding of dalazatide to external residues in Kv1.3 frees the filter to swing inwards. The extracellular end of the selectivity filter narrows allowing K+ to move in single file through the pore typical of conventional knock-on conduction. Inter-subunit hydrogen bonds that stabilize the outer pore in the dalazatide-bound structure are equivalent to those in open-conducting conformations of Kv channels. However, the intra-subunit bond that fastens the filter to the pore-helix is absent, suggesting an incomplete reversal of the process. These mechanisms define how Kv channels self-regulate the flow of K+ by changing the conformation of the selectivity filter.

Published
2022

34. Dark Channel Prior-Based Image Dehazing Algorithm for Single Outdoor Image

Author

Kumari, Lalita, Bibhu, Vimal, Bhushan, Shashi, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Singh, Yashwant, editor, Singh, Pradeep Kumar, editor, Kolekar, Maheshkumar H., editor, Kar, Arpan Kumar, editor, and Gonçalves, Paulo J. Sequeira, editor

Published
2023
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35. Security Attacks, Requirements and Simulative Analysis of QoS in WSN

Author

Rai, Praveen Kumar, Rai, Arun Kumar, Rai, Vipin, Bhushan, Shashi, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Maurya, Sudhanshu, editor, Peddoju, Sateesh K., editor, Ahmad, Badlishah, editor, and Chihi, Ines, editor

Published
2023
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50. Extremophile

Author

Bhushan, Shashi, primary, U., Jayakrishnan, additional, Raychaudhuri, Shaon, additional, and Simesk, Halis, additional

Published
2023
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