Search

A GIS-based approach was used in this study to assess 10 years of land-use change in the lower Shivalik landscape of the Western Himalayas, India. The landscape encompasses two major protected areas which are home to a thriving population of large mammals. The main objective was to identify the changes in the land use pattern, specifically after forming a new tiger reserve in the landscape. Landsat 8 and 4 imagery were used for the time series analysis for the years 2018, 2013, and 2008, respectively. The change was calculated using nine land use classes, with mixed forest showing the highest change value, followed by agriculture, grassland, and scrub. The dense forest area increased immensely after the formation of the new tiger reserve. The results for dense and mixed forest classes also identified less fragmentation in the number of patches during the same time. Even though most of the landscape is within the boundaries of a protected area, the change in land use forms is noticeable. As development activities continue to expand, this region will face increased strain, which will impact the area's natural biodiversity. To protect that, a long-term conservation management effort is required. [ABSTRACT FROM AUTHOR]

The current global epidemic of hypertension is not a disease in and of itself but rather a significant risk factor for serious cardiovascular conditions such as peripheral artery disease, heart failure, myocardial infarction, and stroke. Although many medications that work through various mechanisms of action are available on the market in conventional formulations to treat hypertension, these medications face significant difficulties with their bioavailability, dosing, and associated side effects, which significantly reduces the effectiveness of their therapeutic interventions. Numerous studies have shown that nanocarriers and nanoformulations can minimize the toxicity associated with high doses of the drug while greatly increasing the drug's bioavailability and reducing the frequency of dosing.

This review sheds light on the difficulties posed by traditional antihypertensive formulations and highlights the necessity of oral nanoparticulate systems to solve these issues. Because hypertension has a circadian blood pressure pattern, chronotherapeutics can be very important in treating the condition. On the other hand, nanoparticulate systems can be very important in managing hypertension., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)