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2. Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study

Author

Ercan, Ayse Bahar, Aronson, Melyssa, Fernandez, Nicholas R, Chang, Yuan, Levine, Adrian, Liu, Zhihui Amy, Negm, Logine, Edwards, Melissa, Bianchi, Vanessa, Stengs, Lucie, Chung, Jiil, Al-Battashi, Abeer, Reschke, Agnes, Lion, Alex, Ahmad, Alia, Lassaletta, Alvaro, Reddy, Alyssa T, Al-Darraji, Amir F, Shah, Amish C, Van Damme, An, Bendel, Anne, Rashid, Aqeela, Margol, Ashley S, Kelly, Bethany L, Pencheva, Bojana, Heald, Brandie, Lemieux-Anglin, Brianna, Crooks, Bruce, Koschmann, Carl, Gilpin, Catherine, Porter, Christopher C, Gass, David, Samuel, David, Ziegler, David S, Blumenthal, Deborah T, Kuo, Dennis John, Hamideh, Dima, Basel, Donald, Khuong-Quang, Dong-Anh, Stearns, Duncan, Opocher, Enrico, Carceller, Fernando, Baris Feldman, Hagit, Toledano, Helen, Winer, Ira, Scheers, Isabelle, Fedorakova, Ivana, Su, Jack M, Vengoechea, Jaime, Sterba, Jaroslav, Knipstein, Jeffrey, Hansford, Jordan R, Gonzales-Santos, Julieta Rita, Bhatia, Kanika, Bielamowicz, Kevin J, Minhas, Khurram, Nichols, Kim E, Cole, Kristina A, Penney, Lynette, Hjort, Magnus Aasved, Sabel, Magnus, Gil-da-Costa, Maria Joao, Murray, Matthew J, Miller, Matthew, Blundell, Maude L, Massimino, Maura, Al-Hussaini, Maysa, Al-Jadiry, Mazin F, Comito, Melanie A, Osborn, Michael, Link, Michael P, Zapotocky, Michal, Ghalibafian, Mithra, Shaheen, Najma, Mushtaq, Naureen, Waespe, Nicolas, Hijiya, Nobuko, Fuentes-Bolanos, Noemi, Ahmad, Olfat, Chamdine, Omar, Roy, Paromita, Pichurin, Pavel N, Nyman, Per, Pearlman, Rachel, Auer, Rebecca C, Sukumaran, Reghu K, Kebudi, Rejin, Dvir, Rina, Raphael, Robert, Elhasid, Ronit, McGee, Rose B, Chami, Rose, Noss, Ryan, Tanaka, Ryuma, Raskin, Salmo, Sen, Santanu, Lindhorst, Scott, Perreault, Sebastien, Caspi, Shani, Riaz, Shazia, Constantini, Shlomi, Albert, Sophie, Chaleff, Stanley, Bielack, Stefan, Chiaravalli, Stefano, Cramer, Stuart Louis, Roy, Sumita, Cahn, Suzanne, Penna, Suzanne, Hamid, Syed Ahmer, Ghafoor, Tariq, Imam, Uzma, Larouche, Valerie, Magimairajan Issai, Vanan, Foulkes, William D, Lee, Yi Yen, Nathan, Paul C, Maruvka, Yosef E, Greer, Mary-Louise C, Durno, Carol, Shlien, Adam, Ertl-Wagner, Birgit, Villani, Anita, Malkin, David, Hawkins, Cynthia, Bouffet, Eric, Das, Anirban, and Tabori, Uri

Published
2024
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4. Project Portfolio Management (PPM) in Education Domain Using Skill Matcher Model

Author

Bhatia, Kanika, Chakraverty, Shampa, Nagpal, Sushama, Kumar, Amit, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martin, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Singh, Pradeep Kumar, editor, Suryadevara, Nagender Kumar, editor, Sharma, Sudhir Kumar, editor, and Singh, Amit Prakash, editor

Published
2020
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5. Extraction of Technical and Non-technical Skills for Optimal Project-Team Allocation

Author

Bhatia, Kanika, Chakraverty, Shampa, Nagpal, Sushama, Kumar, Amit, Lamba, Mohit, Poddar, Anupam, Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Agarwal, Sonali, editor, Verma, Shekhar, editor, and Agrawal, Dharma P., editor

Published
2020
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7. AI assisted reader evaluation in acute CT head interpretation (AI-REACT): protocol for a multireader multicase study

Author

Fu, Howell, primary, Novak, Alex, additional, Robert, Dennis, additional, Kumar, Shamie, additional, Tanamala, Swetha, additional, Oke, Jason, additional, Bhatia, Kanika, additional, Shah, Ruchir, additional, Romsauerova, Andrea, additional, Das, Tilak, additional, Espinosa, Abdalá, additional, Grzeda, Mariusz Tadeusz, additional, Narbone, Mariapaola, additional, Dharmadhikari, Rahul, additional, Harrison, Mark, additional, Vimalesvaran, Kavitha, additional, Gooch, Jane, additional, Woznitza, Nicholas, additional, Salik, Nabeeha, additional, Campbell, Alan, additional, Khan, Farhaan, additional, Lowe, David J, additional, Shuaib, Haris, additional, and Ather, Sarim, additional

Published
2024
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8. Teaching Algebra to High School Students Using Desmos Graphing Calculator.

Author

Bhatia, Kanika and Chakraborty, Pinaki

Abstract

Many high school students find algebra difficult because it requires comprehending abstract concepts, performing symbol and sign manipulation, and solving multi-step problems. Graphing calculators can visualize algebraic expressions and equations, and make learning more interactive. We conducted an experiment in which Desmos online graphing calculator was used to augment the algebra lessons of tenth-standard students. The students were taught about polynomials, linear and quadratic equations, and arithmetic progressions during an intervention period lasting seven weeks. We found that properly integrating the graphing calculator with classroom sessions and homework helped the students to perform better in the post-test and also retain the concepts. The students found the graphing calculator to be easy to use and helpful in learning, which increased their interest in algebra and encouraged them to practice algebra regularly. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Trivalent Gd incorporated Zn2SiO4phosphor material for EPR and luminescence investigations

Author

Singh, Vijay, Bhatia, Kanika, Rao, Allam Srinivasa, and Joo, Ji Bong

Abstract

Zn2SiO4:Gd3+powder was obtained by the sol–gel preparation technique and then characterized by using Fourier-transform infrared spectroscopy and X-ray diffraction techniques. The sample exhibited photoluminescence in the ultraviolet spectral zone with a maximum emission wavelength of 314 nm. Ultraviolet emission in the range of 305–320 nm is also called ultraviolet-B emission. This UV range emission is used in lamps for skin treatment and phototherapy. The electron paramagnetic resonance spectrum recorded for the Zn2SiO4:0.015Gd3+phosphor revealed gvalues of 3.46, 2.64, and 2.20, confirming the presence of Gd3+ions in the small ligand field. Furthermore, Gd3+ions attain tetrahedral symmetry in the prepared host compound.

Published
2024
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15. The Clinical and Biological Landscape of Constitutional Mismatch Repair Deficiency: An IRRDC Study

Author

Ercan, Ayse Bahar, primary, Aronson, Melyssa, additional, Fernandez, Nicholas R., additional, Chang, Yuan, additional, Levine, Adrian, additional, Liu, Amy Zhihui, additional, Negm, Logine, additional, Edwards, Melissa, additional, Bianchi, Vanessa, additional, Stengs, Lucie, additional, Chung, Brian, additional, Al-Battashi, Abeer, additional, Reschke, Agnes, additional, Lion, Alex, additional, Ahmad, Alia, additional, Lassaletta, Alvaro, additional, Reddy, Alyssa, additional, Al-Darraji, Amir Fadhil, additional, Shah, Amish C., additional, Van Damme, An, additional, Bendel, Anne E., additional, Rashid, Aqeela, additional, Margol, Ashley S., additional, Kelly, Bethany L., additional, Pencheva, Bojana, additional, Heald, Brandie, additional, Anglin, Brianna Lemieux, additional, Crooks, Bruce, additional, Koschmann, Carl, additional, Gilpin, Catherine, additional, Porter, Christopher C., additional, Gass, David, additional, Samuel, David, additional, Ziegler, David S., additional, Blumenthal, Deborah T., additional, Kuo, Dennis John, additional, Hamideh, Dima, additional, Basel, Donald, additional, Khuong Quang, Dong Anh, additional, Stearns, Duncan, additional, Opocher, Enrico, additional, Carcellar, Fernando, additional, Feldman, Hagit Baris, additional, Toledano, Helen, additional, Winer, Ira S., additional, Scheers, Isabelle, additional, Fedorakova, Ivana, additional, Su, Jack M., additional, Barrios, Jaime Vengoechea, additional, Sterba, Jaroslav, additional, Knipstein, Jeffrey, additional, Hansford, Jordan R., additional, Gonzales-Santos, Julieta Rita, additional, Bhatia, Kanika, additional, Bielamowicz, Kevin J., additional, Minhas, Khurram, additional, Nichols, Kim E., additional, Cole, Kristina A., additional, Penney, Lynette, additional, Hjort, Magnus Aasved, additional, Sabel, Magnus, additional, Gil-da-Costa, Maria Joao, additional, Murray, Matthew J., additional, Miller, Matthew, additional, Blundell, Maude, additional, Massimino, Maura, additional, Al-Hussaini, Maysa, additional, Al-Jadiry, Mazin Faisal, additional, Comito, Melanie A., additional, Osborn, Michael, additional, Link, Michael P., additional, Zapotocky, Michal, additional, Ghalibafian, Mithra, additional, Shaheen, Najma, additional, Mushtaq, Naureen, additional, Waespe, Nicolas, additional, Hijiya, Nobuko, additional, Fuentes Bolanos, Noemi, additional, Ahmad, Olfat, additional, Chamdine, Omar, additional, Roy, Paromita, additional, Pichurin, Pavel N., additional, Nymen, Per, additional, Pearlman, Rachel, additional, Auer, Rebecca C., additional, Sukumaran, Reghu K., additional, Kebudi, Rejin, additional, Dvir, Rina, additional, Raphael, Robert, additional, Elhasid, Ronit, additional, McGee, Rose B., additional, Chami, Rose, additional, Noss, Ryan, additional, Tanaka, Ryuma, additional, Raskin, Salmo, additional, Sen, Santanu, additional, Lindhorst, Scott, additional, Perreault, Sebastian, additional, Caspi, Shani, additional, Riaz, Shazia, additional, Constantini, Shlomi, additional, Albert, Sophie, additional, Chaleff, Stanley, additional, Bielack, Stefan S., additional, Chiaravalli, Stefano, additional, Cramer, Stuart Louis, additional, Roy, Sumita, additional, Cahn, Suzanne, additional, Penna, Suzanne, additional, Hamid, Syed Ahmer, additional, Ghafoor, Tariq, additional, Imam, Uzma, additional, Larouche, Valerie, additional, MagimairajanIssai, Vanan, additional, Foulkes, William, additional, Lee, Yi Yen, additional, Maruvka, Yosef E., additional, Greer, Mary-Louise C., additional, Durno, Carol, additional, Shlien, Adam, additional, Ertl-Wagner, Birgit, additional, Villani, Anita, additional, Malkin, David, additional, Hawkins, Cynthia, additional, Bouffet, Eric, additional, Das, Anirban, additional, and Tabori, Uri, additional

Published
2023
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17. IMMU-13. Dual CTLA4/ PD-1 blockade improves survival for replication-repair deficient high-grade gliomas failing single agent PD-1 inhibition: An IRRDC study

Author

Das, Anirban, primary, Morgenstern, Daniel, additional, Bianchi, Vanessa, additional, Sudhaman, Sumedha, additional, Edwards, Melissa, additional, Stengs, Lucie, additional, Larouche, Valerie, additional, Samuel, David, additional, Van Damme, An, additional, Gass, David, additional, Ziegler, David, additional, Bielack, Stefan, additional, Zelcer, Shayna, additional, Yalon, Michal, additional, Constantini, Shlomi, additional, Sarosiek, Tomasz, additional, Libionka, Witold, additional, Nichols, Kim, additional, De Mola, Rebecca Loret, additional, Bielamowicz, Kevin, additional, Sabel, Magnus, additional, Frojd, Charlotta, additional, Wood, Matthew D, additional, Migueis, Joana Cristiano Sous, additional, Abongwa, Chenue, additional, Yen, Lee Yi, additional, Stearns, Duncan, additional, Opocher, Enrico, additional, Bhatia, Kanika, additional, Sen, Santanu, additional, Cantero, Eduardo Quiroga, additional, Paez, Palma Solano, additional, Crooks, Bruce, additional, Magimairajan, Vanan, additional, Reddy, Alyssa, additional, Adamski, Jenny, additional, Mason, Gary, additional, Lindhorst, Scott, additional, Aronson, Melyssa, additional, Ertl-Wagner, Birgit, additional, Hawkins, Cynthia, additional, Bouffet, Eric, additional, and Tabori, Uri, additional

Published
2022
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20. Optimal Detection of Cardiac Sequelae The Need for Rigorous, Harmonized Magnetic Resonance Studies in Pediatric Survivors

Author

Toro, Claudia, Elliott, David A, La Gerche, Andre, Lange, Peter W, Bolk, Francesca, O'Sullivan, Michael, Bhatia, Kanika, and Conyers, Rachel

Subjects
cancer survivorship, Science & Technology, Cardiac & Cardiovascular Systems, Oncology, CHILDHOOD-CANCER, screening, Cardiovascular System & Cardiology, comparative effectiveness, ECHOCARDIOGRAPHY, Life Sciences & Biomedicine, cardiomyopathy, cardiac magnetic resonance
Abstract

ispartof: JACC: CARDIOONCOLOGY vol:3 issue:1 pages:154-156 ispartof: location:United States status: published

Published
2021

21. Growth hormone and targeted oncological agents: Are we stopping children with brain tumours from reaching their true height potential?

Author

Walker, Hannah, primary, Khuong Quang, Dong Anh, additional, Campbell, Martin, additional, Bhatia, Kanika, additional, Williams, Molly, additional, Sullivan, Michael, additional, Eisenstat, David D, additional, Kao, Kung‐Ting, additional, Ng, Jessica, additional, White, Mary, additional, Zacharin, Margaret, additional, and Hansford, Jordan R, additional

Published
2021
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22. The important role of routine cytopathology in pediatric precision oncology

Author

Xie, Jinhan, primary, Kumar, Amit, additional, Dolman, M. Emmy M., additional, Mayoh, Chelsea, additional, Khuong‐Quang, Dong‐Anh, additional, Cadiz, Roxanne, additional, Wong‐Erasmus, Marie, additional, Mould, Emily V. A., additional, Grebert‐Wade, Dylan, additional, Barahona, Paulette, additional, Kamili, Alvin, additional, Tsoli, Maria, additional, Failes, Timothy W., additional, Chow, Shu‐Oi, additional, Arndt, Greg M., additional, Bhatia, Kanika, additional, Marshall, Glenn M., additional, Ziegler, David S., additional, Haber, Michelle, additional, Lock, Richard B., additional, Tyrrell, Vanessa, additional, Lau, Loretta, additional, Athanasatos, Penny, additional, and Gifford, Andrew J., additional

Published
2021
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23. Optimal Detection of Cardiac Sequelae

Author

Toro, Claudia, primary, Elliott, David A., additional, La Gerche, Andre, additional, Lange, Peter W., additional, Bsc, Francesca Bolk, additional, O’Sullivan, Michael, additional, Bhatia, Kanika, additional, and Conyers, Rachel, additional

Published
2021
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24. EPEN-36. THE TREATMENT OUTCOME OF PAEDIATRIC SUPRATENTORIAL C11ORF95-RELA FUSED EPENDYMOMA: A COMBINED REPORT FROM E-HIT SERIES AND AUSTRALIAN NEW ZEALAND CHILDREN’S HAEMATOLOGY/ONCOLOGY GROUP

Author

Ng, Chia Huan, primary, Obrecht, Denise, additional, Buntine, Molly, additional, Wells, Olivia, additional, Campbell, Martin A, additional, Bhatia, Kanika, additional, Sullivan, Michael, additional, Williams, Molly, additional, Quang, Dong Anh Khuong, additional, Kinross, Kathryn, additional, White, Christine, additional, Algar, Elizabeth, additional, Witt, Hendrik, additional, Schuller, Ulrich, additional, Mynarek, Martin, additional, Pietsch, Torsten, additional, Gerber, Nicolas U, additional, Benesch, Martin, additional, Warmuth-Metz, Monika, additional, Kortmann, Rolf, additional, Bison, Brigitte, additional, Taylor, Michael D, additional, Ramaswamy, Vijay, additional, Rutkowski, Stefan, additional, Pfister, Stefan M, additional, Jones, David T W, additional, Gottardo, Nicholas G, additional, Von Hoff, Katja, additional, Pajtler, Kristian W, additional, and Hansford, Jordan R, additional

Published
2020
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26. Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade glioma

Author

Zhukova, Nataliya, primary, Rajagopal, Revathi, additional, Lam, Adrienne, additional, Coleman, Lee, additional, Shipman, Peter, additional, Walwyn, Thomas, additional, Williams, Molly, additional, Sullivan, Michael, additional, Campbell, Martin, additional, Bhatia, Kanika, additional, Gottardo, Nicholas G., additional, and Hansford, Jordan R., additional

Published
2018
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27. Report of a bi-allelic truncating germline mutation in TP53

Author

Brown, Natasha J., primary, Bhatia, Kanika, additional, Teague, Julie, additional, White, Susan M., additional, Lo, Patrick, additional, Challis, Jackie, additional, Beshay, Victoria, additional, Sullivan, Michael, additional, Malkin, David, additional, and Hansford, Jordan R., additional

Published
2018
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29. Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low‐grade glioma.

Author

Zhukova, Nataliya, Rajagopal, Revathi, Lam, Adrienne, Coleman, Lee, Shipman, Peter, Walwyn, Thomas, Williams, Molly, Sullivan, Michael, Campbell, Martin, Bhatia, Kanika, Gottardo, Nicholas G., and Hansford, Jordan R.

Subjects
VASCULAR endothelial growth factors, NEUROFIBROMATOSIS 1, MONOCLONAL antibodies
Abstract

In pediatric low‐grade gliomas not amenable to complete resection, various chemotherapy regimens are the mainstream of treatment. An excellent overall survival of these patients makes justification of the intensification of chemotherapy difficult and calls for the development of new strategies. Bevacizumab, a humanized monoclonal antibody directed against Vascular endothelial growth factor (VEGF), has been successfully used in combination with irinotecan in a number of adult and pediatric studies and reports. Fifteen patients at median age of 7 years old (range 3 months to 15 years) were treated with bevacizumab in combination with conventional low‐toxicity chemotherapy. The majority had chiasmatic/hypothalamic and midline tumors, seven had confirmed BRAF pathway alterations including neurofibromatosis type 1 (2). Fourteen patients had more than one progression and three had radiotherapy. No deaths were documented, PFS at 11 and 15 months was 71.5% ± 13.9% and 44.7% ± 17.6% respectively. At the end of follow‐up 40% of patients has radiologically stable disease, three patients progressed shortly after completion of bevacizumab and two showed mixed response with progression of cystic component. Rapid visual improvement was seen in 6/8 patients, resolution of endocrine symptoms in 2/4 and motor function improvement in 4/6. No relation between histology or BRAF status and treatment response was observed. Treatment‐limiting toxicities included grade 4 proteinuria (2) and hypertension (2) managed with cessation (1) and pausing of therapy plus antihypertensives (1). In conclusion, bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity. This study demonstrates that anti‐VEGF humanized monoclonal antibody bevacizumab is well tolerated and can be effectively used in pediatric patients with unresectable or progressive low‐grade glioma in combination with a number of conventional chemotherapies. Addition of bevacizumab to chemotherapy does not increase toxicity and allows for rapid control of clinical symptoms. However, optimal duration of therapy is yet to be determined in future studies. [ABSTRACT FROM AUTHOR]

Published
2019
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