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31 results on '"Bhati, Mahendra T"'

1. Frontostriatal salience network expansion in individuals in depression

Author

Lynch, Charles J., Elbau, Immanuel G., Ng, Tommy, Ayaz, Aliza, Zhu, Shasha, Wolk, Danielle, Manfredi, Nicola, Johnson, Megan, Chang, Megan, Chou, Jolin, Summerville, Indira, Ho, Claire, Lueckel, Maximilian, Bukhari, Hussain, Buchanan, Derrick, Victoria, Lindsay W., Solomonov, Nili, Goldwaser, Eric, Moia, Stefano, Caballero-Gaudes, Cesar, Downar, Jonathan, Vila-Rodriguez, Fidel, Daskalakis, Zafiris J., Blumberger, Daniel M., Kay, Kendrick, Aloysi, Amy, Gordon, Evan M., Bhati, Mahendra T., Williams, Nolan, Power, Jonathan D., Zebley, Benjamin, Grosenick, Logan, Gunning, Faith M., and Liston, Conor

Published
2024
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3. Aberrant impulse control circuitry in obesity

Author

Barbosa, Daniel A. N., Kuijper, Fiene Marie, Duda, Jeffrey, Wang, Allan R., Cartmell, Samuel C. D., Saluja, Sabir, Cunningham, Tricia, Shivacharan, Rajat S., Bhati, Mahendra T., Safer, Debra L., Lock, James D., Malenka, Robert C., de Oliveira-Souza, Ricardo, Williams, Nolan R., Grossman, Murray, Gee, James C., McNab, Jennifer A., Bohon, Cara, and Halpern, Casey H.

Published
2022
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4. Dual Treatment of Refractory Focal Epilepsy and Obsessive-Compulsive Disorder With Intracranial Responsive Neurostimulation

Author

Kellogg, Marissa A., primary, Ernst, Lia D., additional, Spencer, David C., additional, Datta, Proleta, additional, Klein, Eran, additional, Bhati, Mahendra T., additional, Shivacharan, Rajat S., additional, Nho, Young-Hoon, additional, Barbosa, Daniel A.N., additional, Halpern, Casey H., additional, and Raslan, Ahmed, additional

Published
2024
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5. Deep Transcranial Magnetic Stimulation Combined With Brief Exposure for Posttraumatic Stress Disorder: A Prospective Multisite Randomized Trial

Author

Isserles, Moshe, Tendler, Aron, Roth, Yiftach, Bystritsky, Alexander, Blumberger, Daniel M., Ward, Herbert, Feifel, David, Viner, Laura, Duffy, Walter, Zohar, Joseph, Keller, Corey J., Bhati, Mahendra T., Etkin, Amit, George, Mark S., Filipcic, Igor, Lapidus, Kyle, Casuto, Leah, Vaishnavi, Sandeep, Stein, Ahava, Deutsch, Lisa, Deutsch, Frederic, Morales, Oscar, Daskalakis, Zafiris J., Zangen, Abraham, and Ressler, Kerry J.

Published
2021
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8. Responsive deep brain stimulation guided by ventral striatal electrophysiology of obsession durably ameliorates compulsion

Author

Nho, Young-Hoon, Rolle, Camarin E., Topalovic, Uros, Shivacharan, Rajat S., Cunningham, Tricia N., Hiller, Sonja, Batista, Daniel, Feng, Austin, Espil, Flint M., Kratter, Ian H., Bhati, Mahendra T., Kellogg, Marissa, Raslan, Ahmed M., Williams, Nolan R., Garnett, John, Pesaran, Bijan, Oathes, Desmond J., Suthana, Nanthia, Barbosa, Daniel A.N., and Halpern, Casey H.

Published
2024
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9. A Randomized Sham-Controlled Trial of Deep Brain Stimulation of the Ventral Capsule/Ventral Striatum for Chronic Treatment-Resistant Depression

Author

Dougherty, Darin D., Rezai, Ali R., Carpenter, Linda L., Howland, Robert H., Bhati, Mahendra T., O’Reardon, John P., Eskandar, Emad N., Baltuch, Gordon H., Machado, Andre D., Kondziolka, Douglas, Cusin, Cristina, Evans, Karleyton C., Price, Lawrence H., Jacobs, Karen, Pandya, Mayur, Denko, Timothey, Tyrka, Audrey R., Brelje, Tim, Deckersbach, Thilo, Kubu, Cynthia, and Malone, Donald A., Jr.

Published
2015
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10. Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression

Author

Leuchter, Andrew F., Cook, Ian A., Feifel, David, Goethe, John W., Husain, Mustafa, Carpenter, Linda L., Thase, Michael E., Krystal, Andrew D., Philip, Noah S., Bhati, Mahendra T., Burke, William J., Howland, Robert H., Sheline, Yvette I., Aaronson, Scott T., Iosifescu, Dan V., O'Reardon, John P., Gilmer, William S., Jain, Rakesh, Burgoyne, Karl S., Phillips, Bill, Manberg, Paul J., Massaro, Joseph, Hunter, Aimee M., Lisanby, Sarah H., and George, Mark S.

Published
2015
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11. The genetics of severe depression

Author

Franklin, Clio E., Achtyes, Eric, Altinay, Murat, Bailey, Kala, Bhati, Mahendra T., Carr, Brent R., Conroy, Susan K., Husain, Mustafa M., Khurshid, Khurshid A., Lencz, Todd, McDonald, William M., Mickey, Brian J., Murrough, James, Nestor, Sean, Nickl-Jockschat, Thomas, Nikayin, Sina, Reeves, Kevin, Reti, Irving M., Selek, Salih, Sanacora, Gerard, Trapp, Nicholas T., Viswanath, Biju, Wright, Jesse H., Sullivan, Patrick, Zandi, Peter P., and Potash, James B.

Abstract

Genome-wide association studies (GWASs) of major depressive disorder (MDD) have recently achieved extremely large sample sizes and yielded substantial numbers of genome-wide significant loci. Because of the approach to ascertainment and assessment in many of these studies, some of these loci appear to be associated with dysphoria rather than with MDD, potentially decreasing the clinical relevance of the findings. An alternative approach to MDD GWAS is to focus on the most severe forms of MDD, with the hope that this will enrich for loci of larger effect, rendering their identification plausible, and providing potentially more clinically actionable findings. Here we review the genetics of severe depression by using clinical markers of severity including: age of onset, recurrence, degree of impairment, and treatment with ECT. There is evidence for increased family-based and Single Nucleotide Polymorphism (SNP)-based estimates of heritability in recurrent and early-onset illness as well as severe functional impariment. GWAS have been performed looking at severe forms of MDD and a few genome-wide loci have been identified. Several whole exome sequencing studies have also been performed, identifying associated rare variants. Although these findings have not yet been rigorously replicated, the elevated heritability seen in severe MDD phenotypes suggests the value of pursuing additional genome-wide interrogation of samples from this population. The challenge now is generating a cohort of adequate size with consistent phenotyping that will allow for careful and robust classifications and distinctions to be made. We are currently pursuing such a strategy in our 50-site worldwide Gen-ECT-ics consortium.

Published
2024
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13. National Network of Depression Centers' Recommendations on Harmonizing Clinical Documentation of Electroconvulsive Therapy

Author

Zandi, Peter P., primary, Morreale, Michael, additional, Reti, Irving M., additional, Maixner, Daniel F., additional, McDonald, William M., additional, Patel, Paresh D., additional, Achtyes, Eric, additional, Bhati, Mahendra T., additional, Carr, Brent R., additional, Conroy, Susan K., additional, Cristancho, Mario, additional, Dubin, Marc J., additional, Francis, Andrew, additional, Glazer, Kara, additional, Ingram, Wendy, additional, Khurshid, Khurshid, additional, McClintock, Shawn M., additional, Pinjari, Omar F., additional, Reeves, Kevin, additional, Rodriguez, Nelson F., additional, Sampson, Shirlene, additional, Seiner, Stephen J., additional, Selek, Salih, additional, Sheline, Yvette, additional, Smetana, Roy W., additional, Soda, Takahiro, additional, Trapp, Nicholas T., additional, Wright, Jesse H., additional, Husain, Mustafa, additional, and Weiner, Richard D., additional

Published
2022
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14. 335 Low Frequency Oscillations in the Ventral Nucleus Accumbens Region Guides Brain Responsive Neurostimulation for Loss of Control Eating: An Initial Review of the BITES Trial

Author

Shivacharan, Rajat, primary, Rolle, Cammie, additional, Buch, Vivek, additional, Barbosa, Daniel, additional, Cunningham, Tricia, additional, Safer, Debra, additional, Bohon, Cara, additional, Azagury, Dan, additional, Dunn, Laura, additional, Yutsis, Maya, additional, Tass, Peter A., additional, Williams, Nolan R., additional, Skarpaas, Tara L., additional, Bhati, Mahendra T., additional, Malenka, Rob, additional, Lock, James D., additional, and Halpern, Casey H., additional

Published
2022
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20. Brain-Responsive Neurostimulation for Loss of Control Eating: Early Feasibility Study

Author

Wu, Hemmings, primary, Adler, Sarah, additional, Azagury, Dan E, additional, Bohon, Cara, additional, Safer, Debra L, additional, Barbosa, Daniel A N, additional, Bhati, Mahendra T, additional, Williams, Nolan R, additional, Dunn, Laura B, additional, Tass, Peter A, additional, Knutson, Brian D, additional, Yutsis, Maya, additional, Fraser, Ayesha, additional, Cunningham, Tricia, additional, Richardson, Kara, additional, Skarpaas, Tara L, additional, Tcheng, Thomas K, additional, Morrell, Martha J, additional, Roberts, Laura Weiss, additional, Malenka, Robert C, additional, Lock, James D, additional, and Halpern, Casey H, additional

Published
2020
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28. Cognitive outcome after ventral capsule/ventral striatum stimulation for treatment-resistant major depression

Author

Kubu, Cynthia S, primary, Brelje, Tim, additional, Butters, Meryl A, additional, Deckersbach, Thilo, additional, Malloy, Paul, additional, Moberg, Paul, additional, Tröster, Alexander I, additional, Williamson, Eric, additional, Baltuch, Gordon H, additional, Bhati, Mahendra T, additional, Carpenter, Linda L, additional, Dougherty, Darin D, additional, Howland, Robert H, additional, Rezai, Ali R, additional, and Malone, Donald A, additional

Published
2016
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29. Clinical Manifestations, Diagnosis, and Empirical Treatments for Catatonia

Author

Bhati, Mahendra T., Datto, Catherine J., and O'Reardon, John P.

Subjects
Review
Abstract

Review the medical literature on the history and clinical features of catatonia so as to provide a contemporary clinical guide for successfully diagnosing and treating the various clinical forms of catatonia.RESULTS of MEDLINE computerized searches using search terms 'catatonia', 'treatment of catatonia', 'electroconvulsive therapy and catatonia', 'benzodiazepines and catatonia', clinical case reports, and book chapters covering the medical and psychiatric literature relevant to catatonia and its associated treatments were examined.Academic medical center.None.None.Catatonia is a common but under-recognized clinical syndrome. No large-scale, controlled studies exist to determine the relative effectiveness of current treatments, including sedative-hypnotic medications (benzodiazepines or barbiturates), and electroconvulsive therapy (ECT).Despite the lack of large-scale, controlled studies, benzodiazepines appear to be an effective first-line treatment for catatonia. ECT is now often reserved as a second-line treatment despite more than 60 years of documented efficacy and safety. However, ECT should be viewed as a first-line intervention in cases of severe or malignant catatonias.

Published
2007

30. A Commentary on Attitudes Towards Deep Brain Stimulation for Addiction.

Author

Lee KE, Bhati MT, and Halpern CH

Abstract

Deep brain stimulation (DBS) has proven to be an effective treatment for neurologic disorders such as Parkinson's disease, and is currently being investigated as a therapy for psychiatric diseases such as addiction, major depressive disorder, and obsessive compulsive disorder. In this commentary, we review and discuss the findings presented in the Letter to the Editor entitled "Attitudes towards treating addiction with deep brain stimulation," written by Ali et al 1 . The survey presented in this Letter reported general approval for examining the effects of DBS on addictive disorders in a clinical trial, but highlighted critical areas of concern including informed consent, patient autonomy, appropriate medical practice, passing of clinical trial milestones, and implications on law enforcement.

Published
2016
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31. Clinical manifestations, diagnosis, and empirical treatments for catatonia.

Author

Bhati MT, Datto CJ, and O'Reardon JP

Abstract

Objective: Review the medical literature on the history and clinical features of catatonia so as to provide a contemporary clinical guide for successfully diagnosing and treating the various clinical forms of catatonia., Design: RESULTS of MEDLINE computerized searches using search terms 'catatonia', 'treatment of catatonia', 'electroconvulsive therapy and catatonia', 'benzodiazepines and catatonia', clinical case reports, and book chapters covering the medical and psychiatric literature relevant to catatonia and its associated treatments were examined., Setting: Academic medical center., Participants: None., Measurements: None., Results: Catatonia is a common but under-recognized clinical syndrome. No large-scale, controlled studies exist to determine the relative effectiveness of current treatments, including sedative-hypnotic medications (benzodiazepines or barbiturates), and electroconvulsive therapy (ECT)., Conclusion: Despite the lack of large-scale, controlled studies, benzodiazepines appear to be an effective first-line treatment for catatonia. ECT is now often reserved as a second-line treatment despite more than 60 years of documented efficacy and safety. However, ECT should be viewed as a first-line intervention in cases of severe or malignant catatonias.

Published
2007

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