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Reliability characteristics of repairable systems have been studied in the past in great detail by numerous researchers. Their findings are based mainly on the significant assumption that the repairs are carried out by one or more repair facilities, and the process of repair renews the functional behavior of the components or units in the system. In other words, the statistical properties of the components or units can be restored by carrying out the repair upon failure. This means that failed units may be treated "as good as new" after each repair. In many practical situations we observe that in the process of making a unit as good-as-new, considerable damage will be done to the operational ability of the repair facility, which may reflect upon the repair rates of the units in subsequent repairs. Intuitively, we expect that the average repair time of a unit to increase after each repair. This paper makes an attempt to incorporate these concepts in a two unit warm standby redundant system in which the efficiency, equivalently, repair capacity of the repair facility decreases upon each repair. Subsequently, the process of repair may not contribute significantly in improving the system reliability. In order to increase the system reliability and that the system might be available in the long run, an optimum replacement of the repair facility in terms of the mean time to system failure (MTSF) is suggested. [ABSTRACT FROM AUTHOR]

Background: Type 2 diabetes and obesity have reached epidemic proportions all over the world. Women will account for the majority of diabetic cases by the year 2050. Diet plays an important role in causation, management and complications of obesity and type 2 diabetes which are inter related. Objective: To compare the glycemic control, BMI and blood pressure in different meat consuming pre-menopausal patients of type 2 diabetes. Materials & Methods: This is a retrospective study done from the medical records of the patients of type 2 diabetes. The study group consisted of 100 Female diabetic patients on treatment aged less than 40 years. They were divided into two groups based on their food habits with respect to type of meat consumed (viz. red meat consumers, white meat consumers). Their FBS, PPBS, BMI, Blood pressure and diet history were noted. Statistics: Parameters between red meat & white meat consumers were compared by unpaired t-test. All tests were two-tailed and p< 0.05 is considered as significant. Results - The data when analysed statistically revealed that red meat consumption was positively associated with poor glycemic control in terms of both FBS and PPBS (p < 0.0005). There was a significant association of red meat consumption with BMI and blood pressure (p <0.0005 and p=0.0001 respectively. Conclusion - Our study indicates that consumption of red meat may aggravate indices of glycemic control, Obesity and blood pressure in premenopausal patients with type 2 diabetes. Hormonal protection provided by estrogen is overridden by the consumption of red meat. Moderation of red meat consumption should be advocated to patients of type 2 diabetes. [ABSTRACT FROM AUTHOR]

Parkinson's disease is a major neurodegenerative disorder caused due to deficiency of dopamine in the basal ganglia of the brain. The exact etiology of Parkinson's disease still remains unclear. This CNS disorder may be caused due to oxidative stress, toxin induced free radicals, or drugs that destroys dopamine producing neuron in Substantia nigra. Catalepsy is a symptom of extrapyramidal disorders like Parkinson's disease in animals. Neuroleptic induced catalepsy is an effective animal model for screening the antiparkinsonian activity of a chemical. The results indicate that administration of haloperidol (1mg/kg, i.p) significantly induced catalepsy in Swiss albino mice, which was significantly reversed by the ethanolic extract of Moringa oleifera(200mg/kg i.p). The anticataleptic activity of Moringa oleifera can be due to its antioxidant potential or due to its effect on brain monoamines. [ABSTRACT FROM AUTHOR]