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137 results on '"Bhat, Showkat Ahmad"'

19. Neurotoxicity of Heavy Metals in Fishes: A Mechanistic Approach

Author

Farooq, Sana, primary, Wali, Adil Farooq, additional, Majid, Sabhiya, additional, Rasool, Saiema, additional, Wani, Hilal Ahmad, additional, Bhat, Showkat Ahmad, additional, Ali, Shafat, additional, Echikoti, Rafiqa, additional, Rasool, Shabhat, additional, Ahmad, Ajaz, additional, and Rehman, Muneeb U., additional

Published
2021
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29. A Review on Dry Anaerobic Digestion: Existing Technologies, Performance Factors, Challenges, and Recommendations.

Author

Hayyat, Umer, Khan, Muhammad Usman, Sultan, Muhammad, Zahid, Umair, Bhat, Showkat Ahmad, and Muzamil, Mohd

Subjects
ANAEROBIC digestion, ENVIRONMENTAL impact analysis, RENEWABLE energy sources, FEEDSTOCK, WASTE management
Abstract

With the increase in the growing rate of municipal solid waste throughout the world and due to the high moisture and organic components of the organic fraction of municipal solid waste, dry anaerobic digestion has become the future direction to cope with this waste while reducing the impact on the environment, including climate change. Dry anaerobic digestion has become a promising technology that converts the organic fraction of municipal solid waste into combustible biogases, which can be used as an alternative energy source. However, the technology faces several challenges that must be addressed to enhance its performance and adoption. This paper provides a comprehensive analysis of the current technologies used for dry anaerobic digestion in OFMSW and delves into the various factors that influence the performance of these technologies. This review paper also identifies and discusses the challenges faced in optimizing and scaling up these technologies, such as feedstock pretreatment requirements, characteristics of inoculum, and other crucial parameters. [ABSTRACT FROM AUTHOR]

Published
2024
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30. DMSO–KOH mediated stereoselective synthesis of Z-enamides: an expeditious route to Z-enamide bearing natural products.

Author

Bhat, Showkat Ahmad, Ahmed, Qazi Naveed, and Bhat, Khursheed Ahmad

Subjects
*NATURAL products, *STEREOSELECTIVE reactions, *FUNCTIONAL groups, *DIMETHYL sulfoxide, *ALKYNES, *AMIDATION
Abstract

An efficient strategy towards stereoselective amidation of alkynes is reported. The given method features operational simplicity, excellent functional group tolerance, broad substrate scope and fast kinetics to furnish Z-enamides. Moreover, the method was successfully applied for the facile synthesis of the natural products lansiumamide A, lansiumamide B and Z-alatamide. Notably, DMSO plays two vital roles: hydrogen source and solvent. [ABSTRACT FROM AUTHOR]

Published
2024
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45. I2-DMSO Promoted Deaminative Coupling Reactions of Glycine Esters: Access to 5-(Methylthio)pyridazin-3(2H)-ones

Author

Bhat, Showkat Ahmad, Bhat, Mohammad Yaqoob, Rather, Suhail Ahmad, Jameel, Salman, Bhat, Khursheed Ahmad, and Ahmed, Qazi Naveed

Abstract

An unprecedented, one-step strategy for the synthesis of 5-(methylthio)pyridazin-3(2H)-one derivatives has been developed through iodine triggered deaminative coupling of glycine esters with methyl ketones and hydrazine hydrate in DMSO. These transformations in the absence of hydrazine helped to generate different 3-methylthio-4-oxo-enoates in good yields. Notably, DMSO played multiple roles such as oxidant, methylthiolating reagent, and solvent.

Published
2023
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49. Apoptotic Effects of Prunus persica (L) Batsch Leaves against Breast Cancer Cell Line (MDA-MB-231) and Cervical Cancer Cell Line (HeLa) In Vitro

Author

Bhat, Firdous Ahmad, Shafi, Sabeeha, Hilal, Nazia, Bhat, Showkat Ahmad, Rafiqee, Aneequa, Bhat, Firdous Ahmad, Shafi, Sabeeha, Hilal, Nazia, Bhat, Showkat Ahmad, and Rafiqee, Aneequa

Abstract

Background: Apoptosis is a normal physiological phenomenon that plays a pivotal role during embryonic development, retention of tissue homeostasis and pathology. The experimental investigation of apoptotic processes is still challenging and routinely based on the assessment of molecular events like chromatin fragmentation and caspase enzyme activity. The present study was conducted to evaluate the apoptosis inducing effect of the Methanol, aqueous and chloroform extracts of Prunus persica leaves. Methods: Different extracts were obtained by cold extraction process using Methanol, water and Chloroform as solvents. Crude extracts were screened for different phytochemical constituents like flavonoids, tannins, sugars, saponins, and glycosides etc. The apoptotic effect of Prunus persica leaves was examined by DAPI staining assay against MDA-MB-231 (Human breast cancer cell line) and HeLa (Human cervical cancer cell line). Results: The results of the studies revealed that the Chloroform extract have tremendous apoptotic activity on MDA-MB-231 cells and methanolic extract have good apoptotic activity on HeLa cells. Nuclear morphological changes assessed by DAPI shows changes in morphology, apoptotic body formation, cell shrinkage, nuclei that were broken into discrete fragments and cell budding that resulted  in cells of various sizes. Conclusion: The phytochemical screening reveals the presence of alkaloids, tannins, Saponins, steroids and flavonoids. The Chloroform extract has shown more effectiveness and less toxicity against MDA-MB-231 and Methanol extract was more apoptotic against HeLa in comparison to others. The present findings clearly indicated that Prunus persica leaves showed dose dependant cytotoxicity.

Published
2020

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