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7 results on '"Bhat, Abid R."'

2. Microparticles in Human Perspiration as an Inflammatory Response Index.

Author

Imtiyaz, Zuha, Bhopale, Veena M., Arya, Awadhesh K., Bhat, Abid R., and Thom, Stephen R.

Subjects
SCUBA apparatus, INFLAMMATION, BREATHING apparatus, SCUBA diving, EXTRACELLULAR vesicles
Abstract

A blood component analysis is an early step for evaluating inflammatory disorders, but it can be unfeasible in some settings. This pilot study assessed whether extracellular vesicle (EV) changes in perspiration are parallel to those occurring in blood as an alternative or complementary option to diagnose an inflammatory response. In parallel studies, EVs were analyzed in perspiration and blood obtained before and after five self-contained underwater breathing apparatus (SCUBA) divers at the National Aquarium in Baltimore performed a dive to 3.98 m of sea water for 40 min, and five non-divers performed an exercise routine at ambient atmospheric pressure. The results demonstrated that microparticles (MPs) are present in perspiration, their numbers increase in the blood in response to SCUBA diving, and the interleukin (IL)-1β content increases. In contrast, while blood-borne MPs became elevated in response to terrestrial exercise, no statistically significant increases occurred in perspiration, and there were no changes in IL-1β. There were no statistically significant elevations in the exosomes in perspiration or blood in response to SCUBA diving and few changes following terrestrial exercise. These findings suggest that an MP perspiration analysis could be a non-invasive method for detecting inflammatory responses that can occur due to the oxidative stress associated with SCUBA diving. [ABSTRACT FROM AUTHOR]

Published
2024
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4. DOE-Assisted Formulation, Optimization, and Characterization of Tioconazole-Loaded Transferosomal Hydrogel for the Effective Treatment of Atopic Dermatitis: In Vitro and In Vivo Evaluation

Author

Kharwade, Rohini, primary, Ali, Nemat, additional, Gangane, Purushottam, additional, Pawar, Kapil, additional, More, Sachin, additional, Iqbal, Muzaffar, additional, Bhat, Abid R., additional, AlAsmari, Abdullah F., additional, and Kaleem, Mohammed, additional

Published
2023
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7. Blood-Borne Microparticles Are an Inflammatory Stimulus in Type 2 Diabetes Mellitus

Author

Thom, Stephen R., primary, Bhopale, Veena M., additional, Arya, Awadhesh K., additional, Ruhela, Deepa, additional, Bhat, Abid R., additional, Mitra, Nandita, additional, Hoffstad, Ole, additional, Malay, D. Scot, additional, Mirza, Ziad K., additional, Lantis, John C., additional, Lev-Tov, Hadar A., additional, Kirsner, Robert S., additional, Hsia, Ru-Ching, additional, Levinson, Susan L., additional, DiNubile, Mark J., additional, and Margolis, David J., additional

Published
2023
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