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Key Clinical Message: Lateral medullary syndrome, resulting from cerebellar/brainstem infarction, can occur due to cardioembolic stroke from atrial fibrillation caused by rheumatic heart disease. This rare association highlights the importance of strict arrhythmia management, prophylactic anticoagulation, and timely diagnosis to prevent debilitating neurological outcomes. [ABSTRACT FROM AUTHOR]

The selective behaviour of lauryl alcohol to catalyze esterification for the synthesis of tuna free fatty acids (TFFAs) using immobilized Pseudomonas cepacia (PCL) and Thermomyces lanuginosus lipases (TLL) have been investigated. The characterization of both immobilized PCL and TLL and their support immobead-150 is carried out using particle size analyzer, BET method and FT-IR. The suitable reaction conditions have been determined as lauryl alcohol to TFFAs ratio 4:1 (wt/wt), pH 8.0, buffer to TFFAs ratio 1:1 (wt/wt), temperature 50°C and agitation speed 800 rpm. Reusability of both the immobilized lipases for esterification has also been carried out and the activity was stabilized at 60.9% and 47.6% after 5 cycles of repeated use of immobilized PCL and TLL, respectively. Maximum 93.8 wt% Docosahexaenoic acid is recovered in esters with immobilized PCL after 16 h. [ABSTRACT FROM AUTHOR]

Docosahexaenoic acid (DHA) is an important polyunsaturated fatty acid having pharmaceutical potential. It has gained much scientific attention due to its beneficial use in prevention of many diseases such as dyslexia, Alzheimer, schizophrenia, and dyspraxia. The present article deals with the esterification of DHA-rich fatty acids with glycerol. The reaction has been carried out in biphasic solvent system using immobilizedCandida antarcticalipase B (CAL-B) to synthesize glyceride mixture enriched with DHA. The most suitable reaction conditions for esterification of DHA-rich fatty acids with glycerol using immobilized CAL-B were found to be 0.49 g fatty acid mixture with 46 mg glycerol, 3 mL solvent, 26 µL buffer, 200 mg molecular sieves, 7.0 pH, 50°C temperature, 300 rpm agitation speed, and 50 mg enzyme amount. In 120 h, esterification of 75.4% was obtained with 30% triglyceride, 16.1% diglyceride, and 29.3% monoglyceride in the glyceride mixture. DHA could be concentrated in the glyceride mixture up to 87%. [ABSTRACT FROM AUTHOR]