Search

Your search keyword '"Bhaduri, Sarit B."' showing total 340 results
Start Over Author "Bhaduri, Sarit B."
340 results on '"Bhaduri, Sarit B."'

20. Preface

Author

Yang, Lei, primary, Bhaduri, Sarit B., additional, and Webster, Thomas J., additional

Published
2019
Full Text
View/download PDF

22. Nanoscale β-TCP-Laden GelMA/PCL Composite Membrane for Guided Bone Regeneration

Author

Mahmoud, Abdel H, Han, Yuanyuan, Dal-Fabbro, Renan, Daghrery, Arwa, Xu, Jinping, Kaigler, Darnell, Bhaduri, Sarit B, Malda, Jos, Bottino, Marco C, CS_Locomotion, and Equine Musculoskeletal Biology

Subjects
Electrospinning, Gelatin, Regeneration, Tissue engineering, Extracellular matrix, Bone
Abstract

Major advances in the field of periodontal tissue engineering have favored the fabrication of biodegradable membranes with tunable physical and biological properties for guided bone regeneration (GBR). Herein, we engineered innovative nanoscale beta-tricalcium phosphate (β-TCP)-laden gelatin methacryloyl/polycaprolactone (GelMA/PCL-TCP) photocrosslinkable composite fibrous membranes via electrospinning. Chemo-morphological findings showed that the composite microfibers had a uniform porous network and β-TCP particles successfully integrated within the fibers. Compared with pure PCL and GelMA/PCL, GelMA/PCL-TCP membranes led to increased cell attachment, proliferation, mineralization, and osteogenic gene expression in alveolar bone-derived mesenchymal stem cells (aBMSCs). Moreover, our GelMA/PCL-TCP membrane was able to promote robust bone regeneration in rat calvarial critical-size defects, showing remarkable osteogenesis compared to PCL and GelMA/PCL groups. Altogether, the GelMA/PCL-TCP composite fibrous membrane promoted osteogenic differentiation of aBMSCs in vitro and pronounced bone formation in vivo. Our data confirmed that the electrospun GelMA/PCL-TCP composite has a strong potential as a promising membrane for guided bone regeneration.

Published
2023

23. Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone Interface

Author

Golafshan, Nasim, Castilho, Miguel, Daghrery, Arwa, Alehosseini, Morteza, van de Kemp, Tom, Krikonis, Konstantinos, de Ruijter, Mylene, Dal-Fabbro, Renan, Dolatshahi-Pirouz, Alireza, Bhaduri, Sarit B, Bottino, Marco C, Malda, Jos, Golafshan, Nasim, Castilho, Miguel, Daghrery, Arwa, Alehosseini, Morteza, van de Kemp, Tom, Krikonis, Konstantinos, de Ruijter, Mylene, Dal-Fabbro, Renan, Dolatshahi-Pirouz, Alireza, Bhaduri, Sarit B, Bottino, Marco C, and Malda, Jos

Abstract

Periodontitis is a ubiquitous chronic inflammatory, bacteria-triggered oral disease affecting the adult population. If left untreated, periodontitis can lead to severe tissue destruction, eventually resulting in tooth loss. Despite previous efforts in clinically managing the disease, therapeutic strategies are still lacking. Herein, melt electrowriting (MEW) is utilized to develop a compositionally and structurally tailored graded scaffold for regeneration of the periodontal ligament-to-bone interface. The composite scaffolds, consisting of fibers of polycaprolactone (PCL) and fibers of PCL-containing magnesium phosphate (MgP) were fabricated using MEW. To maximize the bond between bone (MgP) and ligament (PCL) regions, we evaluated two different fiber architectures in the interface area. These were a crosshatch pattern at a 0/90° angle and a random pattern. MgP fibrous scaffolds were able to promote in vitro bone formation even in culture media devoid of osteogenic supplements. Mechanical properties after MgP incorporation resulted in an increase of the elastic modulus and yield stress of the scaffolds, and fiber orientation in the interfacial zone affected the interfacial toughness. Composite graded MEW scaffolds enhanced bone fill when they were implanted in an in vivo periodontal fenestration defect model in rats. The presence of an interfacial zone allows coordinated regeneration of multitissues, as indicated by higher expression of bone, ligament, and cementoblastic markers compared to empty defects. Collectively, MEW-fabricated scaffolds having compositionally and structurally tailored zones exhibit a good mimicry of the periodontal complex, with excellent regenerative capacity and great potential as a defect-specific treatment strategy.

Published
2023

24. Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

Author

Equine Musculoskeletal Biology, dES RMSC, Daghrery, Arwa, Ferreira, Jessica A, Xu, Jinping, Golafshan, Nasim, Kaigler, Darnell, Bhaduri, Sarit B, Malda, Jos, Castilho, Miguel, Bottino, Marco C, Equine Musculoskeletal Biology, dES RMSC, Daghrery, Arwa, Ferreira, Jessica A, Xu, Jinping, Golafshan, Nasim, Kaigler, Darnell, Bhaduri, Sarit B, Malda, Jos, Castilho, Miguel, and Bottino, Marco C

Published
2023

25. Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone Interface

Author

CS_Locomotion, Equine Musculoskeletal Biology, Locomotion - Equine Sciences, Golafshan, Nasim, Castilho, Miguel, Daghrery, Arwa, Alehosseini, Morteza, van de Kemp, Tom, Krikonis, Konstantinos, de Ruijter, Mylene, Dal-Fabbro, Renan, Dolatshahi-Pirouz, Alireza, Bhaduri, Sarit B, Bottino, Marco C, Malda, Jos, CS_Locomotion, Equine Musculoskeletal Biology, Locomotion - Equine Sciences, Golafshan, Nasim, Castilho, Miguel, Daghrery, Arwa, Alehosseini, Morteza, van de Kemp, Tom, Krikonis, Konstantinos, de Ruijter, Mylene, Dal-Fabbro, Renan, Dolatshahi-Pirouz, Alireza, Bhaduri, Sarit B, Bottino, Marco C, and Malda, Jos

Published
2023

26. Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone Interface

Author

Orthopaedie Onderzoek, Other research (not in main researchprogram), Regenerative Medicine and Stem Cells, Golafshan, Nasim, Castilho, Miguel, Daghrery, Arwa, Alehosseini, Morteza, van de Kemp, Tom, Krikonis, Konstantinos, de Ruijter, Mylene, Dal-Fabbro, Renan, Dolatshahi-Pirouz, Alireza, Bhaduri, Sarit B., Bottino, Marco C., Malda, Jos, Orthopaedie Onderzoek, Other research (not in main researchprogram), Regenerative Medicine and Stem Cells, Golafshan, Nasim, Castilho, Miguel, Daghrery, Arwa, Alehosseini, Morteza, van de Kemp, Tom, Krikonis, Konstantinos, de Ruijter, Mylene, Dal-Fabbro, Renan, Dolatshahi-Pirouz, Alireza, Bhaduri, Sarit B., Bottino, Marco C., and Malda, Jos

Published
2023

27. Tissue-specific melt electrowritten polymeric scaffolds for coordinated regeneration of soft and hard periodontal tissues

Author

Orthopaedie Onderzoek, Regenerative Medicine and Stem Cells, Other research (not in main researchprogram), Daghrery, Arwa, Ferreira, Jessica A., Xu, Jinping, Golafshan, Nasim, Kaigler, Darnell, Bhaduri, Sarit B., Malda, Jos, Castilho, Miguel, Bottino, Marco C., Orthopaedie Onderzoek, Regenerative Medicine and Stem Cells, Other research (not in main researchprogram), Daghrery, Arwa, Ferreira, Jessica A., Xu, Jinping, Golafshan, Nasim, Kaigler, Darnell, Bhaduri, Sarit B., Malda, Jos, Castilho, Miguel, and Bottino, Marco C.

Published
2023

30. Composite Graded Melt Electrowritten Scaffolds for Regeneration of the Periodontal Ligament-to-Bone Interface

Author

Golafshan, Nasim, primary, Castilho, Miguel, additional, Daghrery, Arwa, additional, Alehosseini, Morteza, additional, van de Kemp, Tom, additional, Krikonis, Konstantinos, additional, de Ruijter, Mylene, additional, Dal-Fabbro, Renan, additional, Dolatshahi-Pirouz, Alireza, additional, Bhaduri, Sarit B., additional, Bottino, Marco C., additional, and Malda, Jos, additional

Published
2023
Full Text
View/download PDF

43. A Highly Ordered, Nanostructured Fluorinated CaP-Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration

Author

Equine Musculoskeletal Biology, dES RMSC, Daghrery, Arwa, Ferreira, Jessica A, de Souza Araújo, Isaac J, Clarkson, Brian H, Eckert, George J, Bhaduri, Sarit B, Malda, Jos, Bottino, Marco C, Equine Musculoskeletal Biology, dES RMSC, Daghrery, Arwa, Ferreira, Jessica A, de Souza Araújo, Isaac J, Clarkson, Brian H, Eckert, George J, Bhaduri, Sarit B, Malda, Jos, and Bottino, Marco C

Published
2021

44. A Highly Ordered, Nanostructured Fluorinated CaP-Coated Melt Electrowritten Scaffold for Periodontal Tissue Regeneration

Author

Orthopaedie Onderzoek, Regenerative Medicine and Stem Cells, Daghrery, Arwa, Ferreira, Jessica A., de Souza Araújo, Isaac J., Clarkson, Brian H., Eckert, George J., Bhaduri, Sarit B., Malda, Jos, Bottino, Marco C., Orthopaedie Onderzoek, Regenerative Medicine and Stem Cells, Daghrery, Arwa, Ferreira, Jessica A., de Souza Araújo, Isaac J., Clarkson, Brian H., Eckert, George J., Bhaduri, Sarit B., Malda, Jos, and Bottino, Marco C.

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results