Author: "Beynon O" - Searchworks@Jio Institute Digital Library Search Results

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Author: Timms, AE, Crane, AM, Sims, AM, Bradbury, L, Beynon, O, Coyne, MRE, Herzberg, I, Abbott, A, Cardon, LR, Duff, GR, Calin, A, Wordsworth, P, and Brown, MA
Published: 2016

Author: Pointon, J, Beynon, O, Jaakkola, E, Laiho, K, Kauppi, M, Kaarela, K, Tuomilehto, J, Brown, M, and Wordsworth, P
Published: 2006

Author: Miles, L, Beynon, O, Woon, P, Blumsohn, A, Eastell, R, Duncan, E, Wass, J, and Brown, M
Published: 2004

Author: Timms, A, Crane, A, Sims, A, Cordell, H, Bradbury, L, Beynon, O, Duff, G, Cardon, L, Calin, A, Wordsworth, P, and Brown, M
Published: 2004

Author: Timms, A. E., Crane, A. M., Sims, A. M., Cordell, H. J., Bradbury, L. A., Abbott, A., Coyne, M. R. E., Beynon, O., Herzberg, I., Duff, G. W., Calin, A., Cardon, L. R., Wordsworth, B. P., Brown, Matthew A., Timms, A. E., Crane, A. M., Sims, A. M., Cordell, H. J., Bradbury, L. A., Abbott, A., Coyne, M. R. E., Beynon, O., Herzberg, I., Duff, G. W., Calin, A., Cardon, L. R., Wordsworth, B. P., and Brown, Matthew A.
Abstract: Ankylosing spondylitis (AS) is a common and highly heritable inflammatory arthropathy. Although the gene HLA-B27 is almost essential for the inheritance of the condition, it alone is not sufficient to explain the pattern of familial recurrence of the disease. We have previously demonstrated suggestive linkage of AS to chromosome 2q13, a region containing the interleukin 1 (IL-1) family gene cluster, which includes several strong candidates for involvement in the disease. In the current study, we describe strong association and transmission of IL-1 family gene cluster single-nucleotide polymorphisms and haplotypes with AS.
Published: 2004

Author: Timms AE, Crane AM, Sims AM, Cordell HJ, Bradbury LA, Abbott A, Coyne MR, Beynon O, Herzberg I, Duff GW, Calin A, Cardon LR, Wordsworth BP, and Brown MA
Subjects: DNA Mutational Analysis, DNA Primers, Electrophoresis, Agar Gel, Gene Frequency, Genotype, HLA-B27 Antigen genetics, Haplotypes genetics, Humans, Inheritance Patterns genetics, Polymorphism, Single Nucleotide genetics, United Kingdom, Chromosomes, Human, Pair 2 genetics, Genetic Predisposition to Disease, Interleukin-1 genetics, Spondylitis, Ankylosing genetics
Abstract: Ankylosing spondylitis (AS) is a common and highly heritable inflammatory arthropathy. Although the gene HLA-B27 is almost essential for the inheritance of the condition, it alone is not sufficient to explain the pattern of familial recurrence of the disease. We have previously demonstrated suggestive linkage of AS to chromosome 2q13, a region containing the interleukin 1 (IL-1) family gene cluster, which includes several strong candidates for involvement in the disease. In the current study, we describe strong association and transmission of IL-1 family gene cluster single-nucleotide polymorphisms and haplotypes with AS.
Published: 2004
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