156 results on '"Bewley, Kevin"'
Search Results
2. Development of a quantitative real-time RT-PCR assay that differentiates between Kyasanur Forest disease virus and Alkhurma hemorrhagic fever virus
- Author
-
N, Sudheesh, Hewson, Roger, Afrough, Babak, Bewley, Kevin, and Arunkumar, Govindakarnavar
- Published
- 2020
- Full Text
- View/download PDF
3. Detection of SARS-CoV-2 BA.2.86 by lateral flow devices
- Author
-
Bown, Abbie, primary, Sweed, Angela, additional, Catton, Matthew, additional, Cowne, Joshua Nelthorpe, additional, Conti-Frith, Hermione, additional, Elderfield, Ruth, additional, Terrey, Jacob, additional, Abib, Hamsa, additional, Lui, Caleb, additional, Fisher, Ella, additional, Bewley, Kevin R., additional, Coombes, Naomi S., additional, Robinson, Donna, additional, Agrawal, Somya, additional, Hallis, Bassam, additional, Blandford, Edward, additional, Fowler, Tom, additional, Williamson, Deborah A., additional, and Vipond, Richard, additional
- Published
- 2023
- Full Text
- View/download PDF
4. The identification of immune-reactive proteins recognised in response to Coxiella burnetii infection
- Author
-
Bewley, Kevin Raymond, Mills, Graham, and Fouch, Sarah Elizabeth
- Subjects
616.9 ,Biomedical Sciences ,Pharmacy - Abstract
Infection with Coxiella burnetii in humans is associated with severe disease, known as Q fever. Acute infection, that can be sub-clinical in nature, can lead to the development of a chronic life-threatening cardiac condition. The largest reported human outbreak of Q fever recently occurred in the Netherlands between 2007 and 2010. This outbreak gave rise to over 4,000 reported human cases and efforts such as the culling of 50,000 pregnant goats in an attempt to control the outbreak. While an effective vaccine exists for protection against infection, it has an unsatisfactory safety profile that has led to it being licenced in only a single country and in a defined group at risk of occupational exposure to infection. In addition, this vaccine involves culturing the organisms at high levels of biological containment; this makes the vaccine expensive to produce and presents a challenge in attaining reproducible batch-to-batch variation. In this work, two species of laboratory animals were infected by the aerosol route to closely mimic the likely natural route of infection in humans. The species investigated were guinea pigs (Dunkin Hartley strain) and mice (BALB/c and A/J strains). The infection in guinea pigs more closely mimicked human acute disease than that in the two different strains of mice: In terms of a more acute febrile response and greater clearance of the organism from the tissues. After clinical recovery from disease, the antibodies from the guinea pigs’ sera were used to isolate immune-reactive proteins found in axenically-grown C. burnetii organisms. Isolation of protein was achieved by picking spots from 2D-PAGE gels corresponding to reactive spots on parallel Western blots as well as immunoprecipitation (pull down) of bacterial protein extracts, a method not previously applied to this type of analysis. These isolated proteins were then identified using nanoLC-electrospray ionisation tandem mass-spectrometry (Q Exactive™ instrument). More than 100 proteins were identified, 71 of which had not been previously described in the literature. The identified proteins were considered for their suitability for inclusion in a future subunit vaccine to protect against Q fever. The most promising candidates were an OmpA-like surface protein similar to a molecule that has already been described as an invasin, two surface-exposed components of the bacterial type IV secretion system (DotA and IcmX), and two hypothetical proteins that warrant further study.
- Published
- 2015
5. Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19
- Author
-
Salguero, Francisco J., White, Andrew D., Slack, Gillian S., Fotheringham, Susan A., Bewley, Kevin R., Gooch, Karen E., Longet, Stephanie, Humphries, Holly E., Watson, Robert J., Hunter, Laura, Ryan, Kathryn A., Hall, Yper, Sibley, Laura, Sarfas, Charlotte, Allen, Lauren, Aram, Marilyn, Brunt, Emily, Brown, Phillip, Buttigieg, Karen R., Cavell, Breeze E., Cobb, Rebecca, Coombes, Naomi S., Darby, Alistair, Daykin-Pont, Owen, Elmore, Michael J., Garcia-Dorival, Isabel, Gkolfinos, Konstantinos, Godwin, Kerry J., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas, Ho, Catherine M. K., Kennard, Chelsea L., Knott, Daniel, Leung, Stephanie, Lucas, Vanessa, Mabbutt, Adam, Morrison, Alexandra L., Nelson, Charlotte, Ngabo, Didier, Paterson, Jemma, Penn, Elizabeth J., Pullan, Steve, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Tree, Julia A., Turner, Carrie, Vamos, Edith, Wand, Nadina, Wiblin, Nathan R., Charlton, Sue, Dong, Xiaofeng, Hallis, Bassam, Pearson, Geoffrey, Rayner, Emma L., Nicholson, Andrew G., Funnell, Simon G., Hiscox, Julian A., Dennis, Mike J., Gleeson, Fergus V., Sharpe, Sally, and Carroll, Miles W.
- Published
- 2021
- Full Text
- View/download PDF
6. ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models
- Author
-
Lambe, Teresa, Spencer, Alexandra J., Thomas, Kelly M., Gooch, Karen E., Thomas, Stephen, White, Andrew D., Humphries, Holly E., Wright, Daniel, Belij-Rammerstorfer, Sandra, Thakur, Nazia, Conceicao, Carina, Watson, Robert, Alden, Leonie, Allen, Lauren, Aram, Marilyn, Bewley, Kevin R., Brunt, Emily, Brown, Phillip, Cavell, Breeze E., Cobb, Rebecca, Fotheringham, Susan A., Gilbride, Ciaran, Harris, Debbie J., Ho, Catherine M. K., Hunter, Laura, Kennard, Chelsea L., Leung, Stephanie, Lucas, Vanessa, Ngabo, Didier, Ryan, Kathryn A., Sharpe, Hannah, Sarfas, Charlotte, Sibley, Laura, Slack, Gillian S., Ulaszewska, Marta, Wand, Nadina, Wiblin, Nathan R., Gleeson, Fergus V., Bailey, Dalan, Sharpe, Sally, Charlton, Sue, Salguero, Francisco J., Carroll, Miles W., and Gilbert, Sarah C.
- Published
- 2021
- Full Text
- View/download PDF
7. Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity
- Author
-
Ryan, Kathryn A., Bewley, Kevin R., Fotheringham, Susan A., Slack, Gillian S., Brown, Phillip, Hall, Yper, Wand, Nadina I., Marriott, Anthony C., Cavell, Breeze E., Tree, Julia A., Allen, Lauren, Aram, Marilyn J., Bean, Thomas J., Brunt, Emily, Buttigieg, Karen R., Carter, Daniel P., Cobb, Rebecca, Coombes, Naomi S., Findlay-Wilson, Steve J., Godwin, Kerry J., Gooch, Karen E., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas H., Humphries, Holly E., Hunter, Laura, Ho, Catherine M. K., Kennard, Chelsea L., Leung, Stephanie, Longet, Stephanie, Ngabo, Didier, Osman, Karen L., Paterson, Jemma, Penn, Elizabeth J., Pullan, Steven T., Rayner, Emma, Skinner, Oliver, Steeds, Kimberley, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Turner, Carrie, Watson, Robert J., Wiblin, Nathan R., Charlton, Sue, Hallis, Bassam, Hiscox, Julian A., Funnell, Simon, Dennis, Mike J., Whittaker, Catherine J., Catton, Michael G., Druce, Julian, Salguero, Francisco J., and Carroll, Miles W.
- Published
- 2021
- Full Text
- View/download PDF
8. A cautionary perspective regarding the isolation and serial propagation of SARS-CoV-2 in Vero cells
- Author
-
Funnell, Simon G. P., Afrough, Babak, Baczenas, John James, Berry, Neil, Bewley, Kevin R., Bradford, Rebecca, Florence, Clint, Duff, Yann Le, Lewis, Mark, Moriarty, Ryan V., Connor, Shelby L. O., Osman, Karen L., Pullan, Steven, Rashid, Sujatha, Richards, Kevin S., Stemple, Kimberly J., and Knezevic, Ivana
- Published
- 2021
- Full Text
- View/download PDF
9. Evaluation of the neutralising antibody response in human and hamster sera against SARS-CoV-2 variants up to and including BA.2.86 using an authentic virus neutralisation assay
- Author
-
Coombes, Naomi S, primary, Bewley, Kevin R, additional, Le Duff, Yann, additional, Alami-Rahmouni, Nassim, additional, Ryan, Kathryn A, additional, Kempster, Sarah, additional, Ferguson, Deborah, additional, Davies, Elizabeth R, additional, Weldon, Thomas M, additional, Cross, Eleanor S, additional, Smith, Lauren, additional, Norris, Conner, additional, Rogers-Broadway, Karly Rai, additional, Lewandowski, Kuiama, additional, Treagus, Samantha, additional, Pullan, Steven T, additional, Hallis, Bassam, additional, Charlton, Sue, additional, Hall, Yper, additional, and Funnell, Simon G. P., additional
- Published
- 2023
- Full Text
- View/download PDF
10. Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens
- Author
-
Lean, Fabian Z. X., Lamers, Mart M., Smith, Samuel P., Shipley, Rebecca, Schipper, Debby, Temperton, Nigel, Haagmans, Bart L., Banyard, Ashley C., Bewley, Kevin R., Carroll, Miles W., Brookes, Sharon M., Brown, Ian, and Nuñez, Alejandro
- Published
- 2020
- Full Text
- View/download PDF
11. Detection of SARS-CoV-2 BA.2.86 by lateral flow devices
- Author
-
Bown, Abbie, Sweed, Angela, Catton, Matthew, Nelthorpe-Cowne, Joshua, Conti-Frith, Hermione, Elderfield, Ruth, Terrey, Jacob, Abib, Hamsa, Lui, Caleb, Fisher, Ella, Bewley, Kevin R., Coombes, Naomi S., Robinson, Donna, Agrawal, Somya, Hallis, Bassam, Blandford, Edward, Fowler, Tom, Williamson, Deborah A., and Vipond, Richard
- Published
- 2024
- Full Text
- View/download PDF
12. The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection
- Author
-
Davies, Elizabeth R., primary, Ryan, Kathryn A., additional, Bewley, Kevin R., additional, Coombes, Naomi S., additional, Salguero, Francisco J., additional, Carnell, Oliver T., additional, Biddlecombe, Sarah, additional, Charlton, Michael, additional, Challis, Amy, additional, Cross, Eleanor S., additional, Handley, Alastair, additional, Ngabo, Didier, additional, Weldon, Thomas M., additional, Hall, Yper, additional, and Funnell, Simon G. P., additional
- Published
- 2023
- Full Text
- View/download PDF
13. Immunisation with purified Coxiella burnetii phase I lipopolysaccharide confers partial protection in mice independently of co-administered adenovirus vectored vaccines
- Author
-
Dold, Christina, primary, Zhu, Henderson, additional, Silva-Reyes, Laura, additional, Blackwell, Luke, additional, Linder, Aline, additional, Bewley, Kevin, additional, Godwin, Kerry, additional, Fotheringham, Susan, additional, Charlton, Sue, additional, Kim, Young Chan, additional, Pollard, Andrew J., additional, and Rollier, Christine S., additional
- Published
- 2023
- Full Text
- View/download PDF
14. Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant
- Author
-
Ryan, Kathryn A., primary, Bewley, Kevin R., additional, Watson, Robert J., additional, Burton, Christopher, additional, Carnell, Oliver, additional, Cavell, Breeze E., additional, Challis, Amy, additional, Coombes, Naomi S., additional, Davies, Elizabeth R., additional, Edun-Huges, Jack, additional, Emery, Kirsty, additional, Fell, Rachel, additional, Fotheringham, Susan A., additional, Gooch, Karen E., additional, Gowan, Kathryn, additional, Handley, Alastair, additional, Harris, Debbie J., additional, Hesp, Richard, additional, Hunter, Laura, additional, Humphreys, Richard, additional, Johnson, Rachel, additional, Kennard, Chelsea, additional, Knott, Daniel, additional, Lister, Sian, additional, Morley, Daniel, additional, Ngabo, Didier, additional, Osman, Karen L., additional, Paterson, Jemma, additional, Penn, Elizabeth J., additional, Pullan, Steven T., additional, Richards, Kevin S., additional, Summers, Sian, additional, Thomas, Stephen R., additional, Weldon, Thomas, additional, Wiblin, Nathan R., additional, Rayner, Emma L., additional, Vipond, Richard T., additional, Hallis, Bassam, additional, Salguero, Francisco J., additional, Funnell, Simon G. P., additional, and Hall, Yper, additional
- Published
- 2023
- Full Text
- View/download PDF
15. SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum
- Author
-
Handley, Alastair, primary, Ryan, Kathryn A., additional, Davies, Elizabeth R., additional, Bewley, Kevin R., additional, Carnell, Oliver T., additional, Challis, Amy, additional, Coombes, Naomi S., additional, Fotheringham, Susan A., additional, Gooch, Karen E., additional, Charlton, Michael, additional, Harris, Debbie J., additional, Kennard, Chelsea, additional, Ngabo, Didier, additional, Weldon, Thomas M., additional, Salguero, Francisco J., additional, Funnell, Simon G. P., additional, and Hall, Yper, additional
- Published
- 2023
- Full Text
- View/download PDF
16. Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents
- Author
-
Coombes, Naomi S., primary, Bewley, Kevin R., additional, Le Duff, Yann, additional, Hurley, Matthew, additional, Smith, Lauren J., additional, Weldon, Thomas M., additional, Osman, Karen, additional, Pullan, Steven, additional, Berry, Neil, additional, Hallis, Bassam, additional, Charlton, Sue, additional, Hall, Yper, additional, and Funnell, Simon G. P., additional
- Published
- 2023
- Full Text
- View/download PDF
17. Influence of Aerosol Delivered BCG Vaccination on Immunological and Disease Parameters Following SARS-CoV-2 Challenge in Rhesus Macaques
- Author
-
White, Andrew D., primary, Sibley, Laura, additional, Sarfas, Charlotte, additional, Morrison, Alexandra L., additional, Bewley, Kevin, additional, Churchward, Colin, additional, Fotheringham, Susan, additional, Gkolfinos, Konstantinos, additional, Gooch, Karen, additional, Handley, Alastair, additional, Humphries, Holly E., additional, Hunter, Laura, additional, Kennard, Chelsea, additional, Longet, Stephanie, additional, Mabbutt, Adam, additional, Moffatt, Miriam, additional, Rayner, Emma, additional, Tipton, Tom, additional, Watson, Robert, additional, Hall, Yper, additional, Bodman-Smith, Mark, additional, Gleeson, Fergus, additional, Dennis, Mike, additional, Salguero, Francisco J., additional, Carroll, Miles, additional, McShane, Helen, additional, Cookson, William, additional, Hopkin, Julian, additional, and Sharpe, Sally, additional
- Published
- 2022
- Full Text
- View/download PDF
18. Convalescence from prototype SARS-CoV-2 protects Syrian hamsters from disease caused by the Omicron variant
- Author
-
Ryan, Kathryn A., primary, Watson, Robert J., additional, Bewley, Kevin R., additional, Burton, Christopher, additional, Carnell, Oliver, additional, Cavell, Breeze E., additional, Challis, Amy, additional, Coombes, Naomi S., additional, Emery, Kirsty, additional, Fell, Rachel, additional, Fotheringham, Susan A., additional, Gooch, Karen E., additional, Gowan, Kathryn, additional, Handley, Alastair, additional, Harris, Debbie J., additional, Humphreys, Richard, additional, Johnson, Rachel, additional, Knott, Daniel, additional, Lister, Sian, additional, Morley, Daniel, additional, Ngabo, Didier, additional, Osman, Karen L., additional, Paterson, Jemma, additional, Penn, Elizabeth J., additional, Pullan, Steven T., additional, Richards, Kevin S., additional, Shaik, Imam, additional, Summers, Sian, additional, Thomas, Stephen R., additional, Weldon, Thomas, additional, Wiblin, Nathan R., additional, Vipond, Richard, additional, Hallis, Bassam, additional, Funnell, Simon G. P., additional, and Hall, Yper, additional
- Published
- 2021
- Full Text
- View/download PDF
19. Finafloxacin, a Novel Fluoroquinolone, Reduces the Clinical Signs of Infection and Pathology in a Mouse Model of Q Fever
- Author
-
Hartley, M. Gill, primary, Norville, Isobel H., additional, Richards, Mark I., additional, Barnes, Kay B., additional, Bewley, Kevin R., additional, Vipond, Julia, additional, Rayner, Emma, additional, Vente, Andreas, additional, Armstrong, Stuart J., additional, and Harding, Sarah V., additional
- Published
- 2021
- Full Text
- View/download PDF
20. mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant
- Author
-
Parry, Helen, primary, Tut, Gokhan, additional, Bruton, Rachel, additional, Faustini, Sian, additional, Stephens, Christine, additional, Saunders, Philip, additional, Bentley, Christopher, additional, Hilyard, Katherine, additional, Brown, Kevin, additional, Amirthalingam, Gayatri, additional, Charlton, Sue, additional, Leung, Stephanie, additional, Chiplin, Emily, additional, Coombes, Naomi S, additional, Bewley, Kevin R, additional, Penn, Elizabeth J, additional, Rowe, Cathy, additional, Otter, Ashley, additional, Watts, Rosie, additional, D'Arcangelo, Silvia, additional, Hallis, Bassam, additional, Makin, Andrew, additional, Richter, Alex, additional, Zuo, Jianmin, additional, and Moss, Paul, additional
- Published
- 2021
- Full Text
- View/download PDF
21. Dose-dependent response to infection with Ebola virus in the ferret model and evidence of viral evolution in the eye.
- Author
-
Watson, Robert J., primary, Tree, Julia, additional, Fotheringham, Susan A., additional, Hall, Yper, additional, Dong, Xiaofeng, additional, Steeds, Kimberley, additional, Gouriet, Jade, additional, Salguero, Francisco J., additional, Burton, Christopher, additional, Pitman, James, additional, Easterbrook, Linda, additional, Richards, Kevin S., additional, Burton, Jane, additional, Bewley, Kevin, additional, Bruce, Christine, additional, Hiscox, Julian A., additional, Carroll, Miles W., additional, and Funnell, Simon G. P., additional
- Published
- 2021
- Full Text
- View/download PDF
22. Author response: mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant
- Author
-
Parry, Helen, primary, Tut, Gokhan, additional, Bruton, Rachel, additional, Faustini, Sian, additional, Stephens, Christine, additional, Saunders, Philip, additional, Bentley, Christopher, additional, Hilyard, Katherine, additional, Brown, Kevin, additional, Amirthalingam, Gayatri, additional, Charlton, Sue, additional, Leung, Stephanie, additional, Chiplin, Emily, additional, Coombes, Naomi S, additional, Bewley, Kevin R, additional, Penn, Elizabeth J, additional, Rowe, Cathy, additional, Otter, Ashley, additional, Watts, Rosie, additional, D'Arcangelo, Silvia, additional, Hallis, Bassam, additional, Makin, Andrew, additional, Richter, Alex, additional, Zuo, Jianmin, additional, and Moss, Paul, additional
- Published
- 2021
- Full Text
- View/download PDF
23. Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques
- Author
-
Bewley, Kevin R., primary, Gooch, Karen, additional, Thomas, Kelly M., additional, Longet, Stephanie, additional, Wiblin, Nathan, additional, Hunter, Laura, additional, Chan, Kin, additional, Brown, Phillip, additional, Russell, Rebecca A., additional, Ho, Catherine, additional, Slack, Gillian, additional, Humphries, Holly E., additional, Alden, Leonie, additional, Allen, Lauren, additional, Aram, Marilyn, additional, Baker, Natalie, additional, Brunt, Emily, additional, Cobb, Rebecca, additional, Fotheringham, Susan, additional, Harris, Debbie, additional, Kennard, Chelsea, additional, Leung, Stephanie, additional, Ryan, Kathryn, additional, Tolley, Howard, additional, Wand, Nadina, additional, White, Andrew, additional, Sibley, Laura, additional, Sarfas, Charlotte, additional, Pearson, Geoff, additional, Rayner, Emma, additional, Xue, Xiaochao, additional, Lambe, Teresa, additional, Charlton, Sue, additional, Gilbert, Sarah, additional, Sattentau, Quentin J., additional, Gleeson, Fergus, additional, Hall, Yper, additional, Funnell, Simon, additional, Sharpe, Sally, additional, Salguero, Francisco J., additional, Gorringe, Andrew, additional, and Carroll, Miles, additional
- Published
- 2021
- Full Text
- View/download PDF
24. T cell and antibody responses induced by a single dose of ChAdOx1 nCoV-19 (AZD1222) vaccine in a phase 1/2 clinical trial
- Author
-
Ewer, Katie J., Barrett, Jordan R., Belij-Rammerstorfer, Sandra, Sharpe, Hannah, Makinson, Rebecca, Morter, Richard, Flaxman, Amy, Wright, Daniel, Bellamy, Duncan, Bittaye, Mustapha, Dold, Christina, Provine, Nicholas M., Aboagye, Jeremy, Fowler, Jamie, Silk, Sarah E., Alderson, Jennifer, Aley, Parvinder K., Angus, Brian, Berrie, Eleanor, Bibi, Sagida, Cicconi, Paola, Clutterbuck, Elizabeth A., Chelysheva, Irina, Folegatti, Pedro M., Fuskova, Michelle, Green, Catherine M., Jenkin, Daniel, Kerridge, Simon, Lawrie, Alison, Minassian, Angela M., Moore, Maria, Mujadidi, Yama, Plested, Emma, Poulton, Ian, Ramasamy, Maheshi N., Robinson, Hannah, Song, Rinn, Snape, Matthew D., Tarrant, Richard, Voysey, Merryn, Watson, Marion E. E., Douglas, Alexander D., Hill, Adrian V. S., Gilbert, Sarah C., Pollard, Andrew J., Lambe, Teresa, Ali, Aabidah, Allen, Elizabeth, Baker, Megan, Barnes, Eleanor, Borthwick, Nicola, Boyd, Amy, Brown-O’Sullivan, Charlie, Burgoyne, Joshua, Byard, Nicholas, Puig, Ingrid Cabrera, Cappuccini, Federica, Cho, Jee-Sun, Clark, Elizabeth, Crocker, Wendy E. M., Datoo, Mehreen S., Davies, Hannah, Donnellan, Francesca R., Dunachie, Susanna Jane, Edwards, Nick J., Elias, Sean C., Furze, Julie, Gilbride, Ciaran, Gorini, Giacomo, Gupta, Gaurav, Harris, Stephanie A., Hodgson, Susanne H. C., Hou, Mimi M., Jackson, Susan, Jones, Kathryn, Kailath, Reshma, King, Lloyd, Larkworthy, Colin W., Li, Yuanyuan, Lias, Amelia M., Linder, Aline, Lipworth, Samuel, Ramon, Raquel Lopez, Madhavan, Meera, Marlow, Emma, Marshall, Julia L., Mentzer, Alexander J., Morrison, Hazel, Moya, Nathifa, Mukhopadhyay, Ekta, Noé, Andrés, Nugent, Fay L., Pipini, Dimitra, Pulido-Gomez, David, Lopez, Fernando Ramos, Ritchie, Adam John, Rudiansyah, Indra, Salvador, Stephannie, Sanders, Helen, Satti, Iman, Shea, Adam, Silk, Sarah, Spencer, Alexandra J., Tanner, Rachel, Taylor, Iona Jennifer, Themistocleous, Yrene, Thomas, Merin, Tran, Nguyen, Truby, Adam, Turner, Cheryl, Turner, Nicola, Ulaszewska, Marta, Worth, Andrew T., Kingham-Page, Lucy, Alvarez, Marco Polo Peralta, Anslow, Rachel, Bates, Louise, Beadon, Kirsten, Beckley, Rebecca, Beveridge, Amy, Bijker, Else Margreet, Blackwell, Luke, Burbage, Jamie, Camara, Susana, Carr, Melanie, Colin-Jones, Rachel, Cooper, Rachel, Cunningham, Christina J., Demissie, Tesfaye, Maso, Claudio Di, Douglas, Naomi, Drake-Brockman, Rachael, Drury, Ruth Elizabeth, Emary, Katherine R. W., Felle, Sally, Feng, Shuo, Silva, Carla Ferreira Da, Ford, Karen J., Francis, Emma, Gracie, Lara, Hamlyn, Joseph, Hanumunthadu, Brama, Harrison, Daisy, Hart, Thomas C., Hawkins, Sophia, Hill, Jennifer, Howe, Elizabeth, Howell, Nicola, Jones, Elizabeth, Keen, Jade, Kelly, Sarah, Kerr, David, Khan, Liaquat, Kinch, Jasmin, Koleva, Stanislava, Lees, Emily A., Lelliott, Alice, Liu, Xinxue, Marchevsky, Natalie G., Marinou, Spyridoula, McEwan, Joanne, Morey, Ella, Morshead, Gertraud, Muller, Jilly, Munro, Claire, Murphy, Sarah, Mweu, Philomena, Nuthall, Elizabeth, O’Brien, Katie, O’Connor, Daniel, O’Reilly, Peter John, Oguti, Blanché, Osborne, Piper, Owino, Nelly, Parker, Kaye, Pfafferott, Katja, Phillips, Daniel, Provstgaard-Morys, Samuel, Ratcliffe, Helen, Rawlinson, Thomas, Rhead, Sarah, Roberts, Hannah, Sanders, Katherine, Silva-Reyes, Laura, Rollier, Christine S., Smith, Catherine C., Smith, David J., Stockdale, Lisa, Szigeti, Anna, Thomas, Tonia M., Thompson, Amber, Tomic, Adriana, Tonks, Susan, Varughese, Rachel, Verheul, Marije K., Vichos, Iason, Walker, Laura, White, Caroline, White, Rachel, Yao, Xin Li, Conlon, Christopher P., Frater, John, Cifuentes, Liliana, Baleanu, Ioana, Bolam, Emma, Boland, Elena, Brenner, Tanja, Damratoski, Brad E., Datta, Chandra, Muhanna, Omar El, Fisher, Richard, Galian-Rubio, Pablo, Hodges, Gina, Jackson, Frederic, Liu, Shuchang, Loew, Lisa, Morgans, Roisin, Morris, Susan Jane, Olchawski, Vicki, Oliveria, Catarina, Parracho, Helena, Pabon, Emilia Reyes, Tahiri-Alaoui, Abdessamad, Taylor, Keja, Williams, Paul, Zizi, Dalila, Arbe-Barnes, Edward H., Baker, Philip, Batten, Alexander, Downing, Charlotte, Drake, Jonathan, English, Marcus Rex, Henry, John Aaron, Iveson, Poppy, Killen, Annabel, King, Thomas B., Larwood, Jessica P. J., Mallett, Garry, Mansatta, Kushal, Mirtorabi, Neginsadat, Patrick-Smith, Maia, Perring, James, Radia, Kajal, Roche, Sophie, Schofield, Ella, Naude, Rebecca te Water, Towner, James, Baker, Natalie, Bewley, Kevin R., Brunt, Emily, Buttigieg, Karen R., Carroll, Miles W., Charlton, Sue, Coombes, Naomi S., Elmore, Michael J., Godwin, Kerry, Hallis, Bassam, Knott, Daniel, McInroy, Lorna, Shaik, Imam, Thomas, Kelly, Tree, Julia A., Blundell, Caitlin L., Cao, Michelangelo, Kelly, Dearbhla, Schmid, Annina, Skelly, Donal T., Themistocleous, Andreas, Dong, Tao, Field, Samantha, Hamilton, Elizabeth, Kelly, Elizabeth, Klenerman, Paul, Knight, Julian C., Lie, Yolanda, Petropoulos, Christos, Sedik, Cynthia, Wrin, Terri, Meddaugh, Gretchen, Peng, Yanchun, Screaton, Gavin, and Stafford, Elizabeth
- Subjects
0301 basic medicine ,biology ,business.industry ,T cell ,Immunogenicity ,General Medicine ,Vaccine efficacy ,General Biochemistry, Genetics and Molecular Biology ,Vaccination ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,Immune system ,Immunity ,030220 oncology & carcinogenesis ,Immunology ,biology.protein ,medicine ,Cytotoxic T cell ,Antibody ,business - Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19), has caused a global pandemic, and safe, effective vaccines are urgently needed1. Strong, Th1-skewed T cell responses can drive protective humoral and cell-mediated immune responses2 and might reduce the potential for disease enhancement3. Cytotoxic T cells clear virus-infected host cells and contribute to control of infection4. Studies of patients infected with SARS-CoV-2 have suggested a protective role for both humoral and cell-mediated immune responses in recovery from COVID-19 (refs. 5,6). ChAdOx1 nCoV-19 (AZD1222) is a candidate SARS-CoV-2 vaccine comprising a replication-deficient simian adenovirus expressing full-length SARS-CoV-2 spike protein. We recently reported preliminary safety and immunogenicity data from a phase 1/2 trial of the ChAdOx1 nCoV-19 vaccine (NCT04400838)7 given as either a one- or two-dose regimen. The vaccine was tolerated, with induction of neutralizing antibodies and antigen-specific T cells against the SARS-CoV-2 spike protein. Here we describe, in detail, exploratory analyses of the immune responses in adults, aged 18–55 years, up to 8 weeks after vaccination with a single dose of ChAdOx1 nCoV-19 in this trial, demonstrating an induction of a Th1-biased response characterized by interferon-γ and tumor necrosis factor-α cytokine secretion by CD4+ T cells and antibody production predominantly of IgG1 and IgG3 subclasses. CD8+ T cells, of monofunctional, polyfunctional and cytotoxic phenotypes, were also induced. Taken together, these results suggest a favorable immune profile induced by ChAdOx1 nCoV-19 vaccine, supporting the progression of this vaccine candidate to ongoing phase 2/3 trials to assess vaccine efficacy. A single dose of the ChAdOx1 nCoV-19 vaccine elicits antibodies and cytokine-producing T cells that might help control or prevent SARS-CoV-2 infection.
- Published
- 2020
- Full Text
- View/download PDF
25. Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera
- Author
-
Zhou, Daming, primary, Dejnirattisai, Wanwisa, additional, Supasa, Piyada, additional, Liu, Chang, additional, Mentzer, Alexander J., additional, Ginn, Helen M., additional, Zhao, Yuguang, additional, Duyvesteyn, Helen M.E., additional, Tuekprakhon, Aekkachai, additional, Nutalai, Rungtiwa, additional, Wang, Beibei, additional, Paesen, Guido C., additional, Lopez-Camacho, Cesar, additional, Slon-Campos, Jose, additional, Hallis, Bassam, additional, Coombes, Naomi, additional, Bewley, Kevin, additional, Charlton, Sue, additional, Walter, Thomas S., additional, Skelly, Donal, additional, Lumley, Sheila F., additional, Dold, Christina, additional, Levin, Robert, additional, Dong, Tao, additional, Pollard, Andrew J., additional, Knight, Julian C., additional, Crook, Derrick, additional, Lambe, Teresa, additional, Clutterbuck, Elizabeth, additional, Bibi, Sagida, additional, Flaxman, Amy, additional, Bittaye, Mustapha, additional, Belij-Rammerstorfer, Sandra, additional, Gilbert, Sarah, additional, James, William, additional, Carroll, Miles W., additional, Klenerman, Paul, additional, Barnes, Eleanor, additional, Dunachie, Susanna J., additional, Fry, Elizabeth E., additional, Mongkolsapaya, Juthathip, additional, Ren, Jingshan, additional, Stuart, David I., additional, and Screaton, Gavin R., additional
- Published
- 2021
- Full Text
- View/download PDF
26. Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera
- Author
-
Supasa, Piyada, primary, Zhou, Daming, additional, Dejnirattisai, Wanwisa, additional, Liu, Chang, additional, Mentzer, Alexander J., additional, Ginn, Helen M., additional, Zhao, Yuguang, additional, Duyvesteyn, Helen M.E., additional, Nutalai, Rungtiwa, additional, Tuekprakhon, Aekkachai, additional, Wang, Beibei, additional, Paesen, Guido C., additional, Slon-Campos, Jose, additional, López-Camacho, César, additional, Hallis, Bassam, additional, Coombes, Naomi, additional, Bewley, Kevin R., additional, Charlton, Sue, additional, Walter, Thomas S., additional, Barnes, Eleanor, additional, Dunachie, Susanna J., additional, Skelly, Donal, additional, Lumley, Sheila F., additional, Baker, Natalie, additional, Shaik, Imam, additional, Humphries, Holly E., additional, Godwin, Kerry, additional, Gent, Nick, additional, Sienkiewicz, Alex, additional, Dold, Christina, additional, Levin, Robert, additional, Dong, Tao, additional, Pollard, Andrew J., additional, Knight, Julian C., additional, Klenerman, Paul, additional, Crook, Derrick, additional, Lambe, Teresa, additional, Clutterbuck, Elizabeth, additional, Bibi, Sagida, additional, Flaxman, Amy, additional, Bittaye, Mustapha, additional, Belij-Rammerstorfer, Sandra, additional, Gilbert, Sarah, additional, Hall, David R., additional, Williams, Mark A., additional, Paterson, Neil G., additional, James, William, additional, Carroll, Miles W., additional, Fry, Elizabeth E., additional, Mongkolsapaya, Juthathip, additional, Ren, Jingshan, additional, Stuart, David I., additional, and Screaton, Gavin R., additional
- Published
- 2021
- Full Text
- View/download PDF
27. Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
- Author
-
Voysey, Merryn, primary, Costa Clemens, Sue Ann, additional, Madhi, Shabir A, additional, Weckx, Lily Y, additional, Folegatti, Pedro M, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Baillie, Vicky L, additional, Barnabas, Shaun L, additional, Bhorat, Qasim E, additional, Bibi, Sagida, additional, Briner, Carmen, additional, Cicconi, Paola, additional, Clutterbuck, Elizabeth A, additional, Collins, Andrea M, additional, Cutland, Clare L, additional, Darton, Thomas C, additional, Dheda, Keertan, additional, Dold, Christina, additional, Duncan, Christopher J A, additional, Emary, Katherine R W, additional, Ewer, Katie J, additional, Flaxman, Amy, additional, Fairlie, Lee, additional, Faust, Saul N, additional, Feng, Shuo, additional, Ferreira, Daniela M, additional, Finn, Adam, additional, Galiza, Eva, additional, Goodman, Anna L, additional, Green, Catherine M, additional, Green, Christopher A, additional, Greenland, Melanie, additional, Hill, Catherine, additional, Hill, Helen C, additional, Hirsch, Ian, additional, Izu, Alane, additional, Jenkin, Daniel, additional, Joe, Carina C D, additional, Kerridge, Simon, additional, Koen, Anthonet, additional, Kwatra, Gaurav, additional, Lazarus, Rajeka, additional, Libri, Vincenzo, additional, Lillie, Patrick J, additional, Marchevsky, Natalie G, additional, Marshall, Richard P, additional, Mendes, Ana V A, additional, Milan, Eveline P, additional, Minassian, Angela M, additional, McGregor, Alastair, additional, Mujadidi, Yama F, additional, Nana, Anusha, additional, Padayachee, Sherman D, additional, Phillips, Daniel J, additional, Pittella, Ana, additional, Plested, Emma, additional, Pollock, Katrina M, additional, Ramasamy, Maheshi N, additional, Ritchie, Adam J, additional, Robinson, Hannah, additional, Schwarzbold, Alexandre V, additional, Smith, Andrew, additional, Song, Rinn, additional, Snape, Matthew D, additional, Sprinz, Eduardo, additional, Sutherland, Rebecca K, additional, Thomson, Emma C, additional, Török, M Estée, additional, Toshner, Mark, additional, Turner, David P J, additional, Vekemans, Johan, additional, Villafana, Tonya L, additional, White, Thomas, additional, Williams, Christopher J, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Pollard, Andrew J, additional, Aban, Marites, additional, Abeyskera, Kushala W.M., additional, Aboagye, Jeremy, additional, Adam, Matthew, additional, Adams, Kirsty, additional, Adamson, James P., additional, Adewatan, Gbadebo, additional, Adlou, Syed, additional, Ahmed, Khatija, additional, Akhalwaya, Yasmeen, additional, Akhalwaya, Saajida, additional, Alcock, Andrew, additional, Ali, Aabidah, additional, Allen, Elizabeth R., additional, Allen, Lauren, additional, Alvernaz, Felipe B., additional, Amorim, Fabio Santos, additional, Andrade, Claudia Sala, additional, Andritsou, Foteini, additional, Anslow, Rachel, additional, Arbe-Barnes, Edward H., additional, Ariaans, Mark P., additional, Arns, Beatriz, additional, Arruda, Laiana, additional, Assad, Luiza, additional, Azi, Paula De Almeida, additional, Azi, Lorena De Almeida, additional, Babbage, Gavin, additional, Bailey, Catherine, additional, Baker, Kenneth F., additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baleanu, Ioana, additional, Bandeira, Danieli, additional, Bara, Anna, additional, Barbosa, Marcella A.S., additional, Barker, Debbie, additional, Barlow, Gavin D., additional, Barnes, Eleanor, additional, Barr, Andrew S., additional, Barrett, Jordan R., additional, Barrett, Jessica, additional, Barrett, Kelly, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beales, Emily, additional, Beckley, Rebecca, additional, Belij-Rammerstorfer, Sandra, additional, Bell, Jonathan, additional, Bellamy, Duncan, additional, Belton, Sue, additional, Berg, Adam, additional, Bermejo, Laura, additional, Berrie, Eleanor, additional, Berry, Lisa, additional, Berzenyi, Daniella, additional, Beveridge, Amy, additional, Bewley, Kevin R., additional, Bharaj, Inderjeet, additional, Bhikha, Sutika, additional, Bhorat, Asad E., additional, Bhorat, Zaheda E., additional, Bijker, Else Margreet, additional, Birch, Sarah, additional, Birch, Gurpreet, additional, Birchall, Kathryn, additional, Bird, Adam, additional, Bird, Olivia, additional, Bisnauthsing, Karen, additional, Bittaye, Mustapha, additional, Blackwell, Luke, additional, Blacow, Rachel, additional, Bletchly, Heather, additional, Blundell, Caitlin L., additional, Blundell, Susannah R., additional, Bodalia, Pritesh, additional, Bolam, Emma, additional, Boland, Elena, additional, Bormans, Daan, additional, Borthwick, Nicola, additional, Bowring, Francesca, additional, Boyd, Amy, additional, Bradley, Penny, additional, Brenner, Tanja, additional, Bridges-Webb, Alice, additional, Brown, Phillip, additional, Brown, Claire, additional, Brown-O'Sullivan, Charlie, additional, Bruce, Scott, additional, Brunt, Emily, additional, Budd, William, additional, Bulbulia, Yusuf A., additional, Bull, Melanie, additional, Burbage, Jamie, additional, Burn, Aileen, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabrera Puig, Ingrid, additional, Calvert, Anna, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Cardona, Rita, additional, Cardoso, João R., additional, Carr, Melanie, additional, Carroll, Miles W., additional, Carson-Stevens, Andrew, additional, Carvalho, Yasmin de M., additional, Casey, Helen R., additional, Cashen, Paul, additional, Castro, Thais R.Y., additional, Castro, Lucia Carratala, additional, Cathie, Katrina, additional, Cavey, Ana, additional, Cerbino-Neto, José, additional, Cezar, Luiz Fernando F., additional, Chadwick, Jim, additional, Chanice, Chanice, additional, Chapman, David, additional, Charlton, Sue, additional, Cheliotis, Katerina S., additional, Chelysheva, Irina, additional, Chester, Oliver, additional, Chiplin, Emily, additional, Chita, Sunder, additional, Cho, Jee-Sun, additional, Cifuentes, Liliana, additional, Clark, Elizabeth, additional, Clark, Matthew, additional, Colin-Jones, Rachel, additional, Collins, Sarah L.K., additional, Colton, Hayley, additional, Conlon, Christopher P., additional, Connarty, Sean, additional, Coombes, Naomi, additional, Cooper, Cushla, additional, Cooper, Rachel, additional, Cornelissen, Lynne, additional, Corrah, Tumena, additional, Cosgrove, Catherine A., additional, Costa, Fernanda Barroso, additional, Cox, Tony, additional, Crocker, Wendy E.M., additional, Crosbie, Sarah, additional, Cullen, Dan, additional, Cunha, Debora R.M.F., additional, Cunningham, Christina J., additional, Cuthbertson, Fiona C., additional, da Costa, Daniel Marinho, additional, Da Guarda, Suzete N. Farias, additional, da Silva, Larissa P., additional, da Silva Moraes, Antonio Carlos, additional, Damratoski, Brad E., additional, Danos, Zsofia, additional, Dantas, Maria T.D.C., additional, Datoo, Mehreen S., additional, Datta, Chandrabali, additional, Davids, Malika, additional, Davies, Sarah L., additional, Davies, Kelly, additional, Davies, Hannah, additional, Davies, Sophie, additional, Davies, Judith, additional, Davis, Elizabeth J., additional, Davis, John, additional, de Carvalho, José A.M., additional, De Jager, Jeanne, additional, de Jesus Jnr, Sergio, additional, De Oliveira Kalid, Lis Moreno, additional, Dearlove, David, additional, Demissie, Tesfaye, additional, Desai, Amisha, additional, Di Marco, Stefania, additional, Di Maso, Claudio, additional, Dinesh, Tanya, additional, Docksey, Claire, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Dos Santos, Tannyth Gomes, additional, Dos Santos, Thainá G., additional, Dos Santos, Erika Pachecho, additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Drury, Ruth, additional, Du Plessis, Joan, additional, Dunachie, Susanna J., additional, Duncan, Andrew, additional, Easom, Nicholas J.W., additional, Edwards, Mandy, additional, Edwards, Nick J., additional, Edwards, Frances, additional, El Muhanna, Omar M., additional, Elias, Sean C., additional, Ellison-Handley, Branwen, additional, Elmore, Michael J., additional, English, Marcus Rex, additional, Esmail, Alisgair, additional, Essack, Yakub Moosa, additional, Farooq, Mutjaba, additional, Fedosyuk, Sofiya, additional, Felle, Sally, additional, Ferguson, Susie, additional, Ferreira Da Silva, Carla, additional, Field, Samantha, additional, Fisher, Richard, additional, Fletcher, James, additional, Fofie, Hazel, additional, Fok, Henry, additional, Ford, Karen J., additional, Fothergill, Ross, additional, Fowler, Jamie, additional, Fraiman, Pedro H.A., additional, Francis, Emma, additional, Franco, Marilia M., additional, Frater, John, additional, Freire, Marilúcia S.M., additional, Fry, Samantha H., additional, Fudge, Sabrina, additional, Furlan Filho, Renato, additional, Furze, Julie, additional, Fuskova, Michelle, additional, Galian-Rubio, Pablo, additional, Garlant, Harriet, additional, Gavrila, Madita, additional, Gibbons, Karyna A., additional, Gilbride, Ciaran, additional, Gill, Hardeep, additional, Godwin, Kerry, additional, Gokani, Karishma, additional, Gonçalves, Maria Luisa Freire, additional, Gonzalez, Isabela G.S., additional, Goodall, Jack, additional, Goodwin, Jayne, additional, Goondiwala, Amina, additional, Gordon-Quayle, Katherine, additional, Gorini, Giacomo, additional, Goyanna, Alvaro, additional, Grab, Janet, additional, Gracie, Lara, additional, Green, Justin, additional, Greenwood, Nicola, additional, Greffrath, Johann, additional, Groenewald, Marisa M., additional, Gunawardene, Anishka, additional, Gupta, Gaurav, additional, Hackett, Mark, additional, Hallis, Bassam, additional, Hamaluba, Mainga, additional, Hamilton, Elizabeth, additional, Hamlyn, Joseph, additional, Hammersley, Daniel, additional, Hanrath, Aidan T., additional, Hanumunthadu, Brama, additional, Harris, Stephanie A., additional, Harris, Clair, additional, Harrison, Thomas D., additional, Harrison, Daisy, additional, Harris-Wright, Tara A., additional, Hart, Thomas C., additional, Hartnell, Birgit, additional, Haughney, John, additional, Hawkins, Sophia, additional, Hayano, Laís Y.M., additional, Head, Ian, additional, Heath, Paul T., additional, Henry, John Aaron, additional, Hermosin Herrera, Macarena, additional, Hettle, David B., additional, Higa, Cristhiane, additional, Hill, Jennifer, additional, Hodges, Gina, additional, Hodgson, Susanne, additional, Horne, Elizea, additional, Hou, Mimi M., additional, Houlihan, Catherine F., additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Humphreys, Jonathan, additional, Humphries, Holly E., additional, Hurley, Katrina, additional, Huson, Claire, additional, Hyams, Catherine, additional, Hyder-Wright, Angela, additional, Ikram, Sabina, additional, Ishwarbhai, Alka, additional, Iveson, Poppy, additional, Iyer, Vidyashankara, additional, Jackson, Frederic, additional, Jackson, Susan, additional, Jaumdally, Shameem, additional, Jeffers, Helen, additional, Jesudason, Natasha, additional, Jones, Carina, additional, Jones, Christopher, additional, Jones, Kathryn, additional, Jones, Elizabeth, additional, Jorge, Marianna Rocha, additional, Joshi, Amar, additional, Júnior, Eduardo A.M.S., additional, Kailath, Reshma, additional, Kana, Faeeza, additional, Kar, Arnab, additional, Karampatsas, Konstantinos, additional, Kasanyinga, Mwila, additional, Kay, Linda, additional, Keen, Jade, additional, Kellett Wright, Johanna, additional, Kelly, Elizabeth J., additional, Kelly, Debbie, additional, Kelly, Dearbhla M., additional, Kelly, Sarah, additional, Kerr, David, additional, Khan, Liaquat, additional, Khozoee, Baktash, additional, Khurana, Ankush, additional, Kidd, Sarah, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, Kinch, Patrick, additional, King, Lloyd D.W., additional, King, Thomas B., additional, Kingham, Lucy, additional, Klenerman, Paul, additional, Kluczna, Diana M., additional, Knapper, Francesca, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Lages, Pedro M., additional, Lang, Matilda, additional, Lang, Gail, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Law, Rebecca, additional, Lawrie, Alison M., additional, Lazarus, Erica M., additional, Leach, Amanda, additional, Lees, Emily A., additional, Lelliott, Alice, additional, Lemm, Nana-Marie, additional, Lessa, Alvaro Edson Ramos, additional, Leung, Stephanie, additional, Li, Yuanyuan, additional, Lias, Amelia M., additional, Liatsikos, Konstantinos, additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Shuchang, additional, Liu, Xinxue, additional, Lloyd, Adam, additional, Lloyd, Stephanie, additional, Loew, Lisa, additional, Lopez Ramon, Raquel, additional, Lora, Leandro Bonecker, additional, Luz, Kleber Giovanni, additional, MacDonald, Jonathan C., additional, MacGregor, Gordon, additional, Madhavan, Meera, additional, Mainwaring, David O., additional, Makambwa, Edson, additional, Makinson, Rebecca, additional, Malahleha, Mookho, additional, Malamatsho, Ross, additional, Mallett, Garry, additional, Manning, Nicola, additional, Mansatta, Kushal, additional, Maoko, Takalani, additional, Marinou, Spyridoula, additional, Marlow, Emma, additional, Marques, Gabriela N., additional, Marriott, Paula, additional, Marshall, Richard P., additional, Marshall, Julia L., additional, Masenya, Masebole, additional, Masilela, Mduduzi, additional, Masters, Shauna K., additional, Mathew, Moncy, additional, Matlebjane, Hosea, additional, Matshidiso, Kedidimetse, additional, Mazur, Olga, additional, Mazzella, Andrea, additional, McCaughan, Hugh, additional, McEwan, Joanne, additional, McGlashan, Joanna, additional, McInroy, Lorna, additional, McRobert, Nicky, additional, McSwiggan, Steve, additional, Megson, Clare, additional, Mehdipour, Savviz, additional, Meijs, Wilma, additional, Mendonça, Renata N.Õ., additional, Mentzer, Alexander J., additional, Mesquita, Ana Carolina F., additional, Miralhes, Patricia, additional, Mirtorabi, Neginsadat, additional, Mitton, Celia, additional, Mnyakeni, Sibusiso, additional, Moghaddas, Fiona, additional, Molapo, Kgaogelo, additional, Moloi, Mapule, additional, Moore, Maria, additional, Moran, Marni, additional, Morey, Ella, additional, Morgans, Róisín, additional, Morris, Susan J., additional, Morris, Sheila, additional, Morrison, Hazel, additional, Morselli, Franca, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Mottay, Lynelle, additional, Moultrie, Andrew, additional, Moyo, Nathifa, additional, Mpelembue, Mushiya, additional, Msomi, Sibekezelo, additional, Mugodi, Yvonne, additional, Mukhopadhyay, Ekta, additional, Muller, Jilly, additional, Munro, Alasdair, additional, Murphy, Sarah, additional, Mweu, Philomena, additional, Myerscough, Christopher, additional, Naik, Gurudutt, additional, Naker, Kush, additional, Nastouli, Eleni, additional, Ndlovu, Bongani, additional, Nikolaou, Elissavet, additional, Njenga, Cecilia, additional, Noal, Helena C., additional, Noé, Andrés, additional, Novaes, Gabrielle, additional, Nugent, Fay L., additional, Nunes, Géssika Lanzillo A., additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Oelofse, Suzette, additional, Oguti, Blanche, additional, Olchawski, Victoria, additional, Oldfield, Neil J., additional, Oliveira, Marianne G., additional, Oliveira, Catarina, additional, Oliveira, Isabelle Silva Queiroz, additional, Oommen-Jose, Aylin, additional, Oosthuizen, Angela, additional, O'Reilly, Paula, additional, O'Reilly, Peter J., additional, Osborne, Piper, additional, Owen, David R.J., additional, Owen, Lydia, additional, Owens, Daniel, additional, Owino, Nelly, additional, Pacurar, Mihaela, additional, Paiva, Brenda V.B., additional, Palhares, Edna M.F., additional, Palmer, Susan, additional, Parracho, Helena M. R.T., additional, Parsons, Karen, additional, Patel, Dipak, additional, Patel, Bhumika, additional, Patel, Faeezah, additional, Patrick-Smith, Maia, additional, Payne, Ruth O., additional, Peng, Yanchun, additional, Penn, Elizabeth J., additional, Pennington, Anna, additional, Peralta Alvarez, Marco Polo, additional, Pereira Stuchi, Bruno Pereira, additional, Perez, Ana Luiza, additional, Perinpanathan, Tanaraj, additional, Perring, James, additional, Perumal, Rubeshan, additional, Petkar, Sahir Yusuf, additional, Philip, Tricia, additional, Phillips, Jennifer, additional, Phohu, Mary Kgomotso, additional, Pickup, Lorinda, additional, Pieterse, Sonja, additional, Pinheiro, Jessica Morgana, additional, Piper, Jo, additional, Pipini, Dimitra, additional, Plank, Mary, additional, Plant, Sinéad, additional, Pollard, Samuel, additional, Pooley, Jennifer, additional, Pooran, Anil, additional, Poulton, Ian, additional, Powers, Claire, additional, Presa, Fernando B., additional, Price, David A., additional, Price, Vivien, additional, Primeira, Marcelo R., additional, Proud, Pamela C., additional, Provstgaard-Morys, Samuel, additional, Pueschel, Sophie, additional, Pulido, David, additional, Quaid, Sheena, additional, Rabara, Ria, additional, Radia, Kajal, additional, Rajapaska, Durga, additional, Rajeswaran, Thurkka, additional, Ramos, Leonardo, additional, Ramos, Alberto San Francisco, additional, Ramos Lopez, Fernando, additional, Rampling, Tommy, additional, Rand, Jade, additional, Ratcliffe, Helen, additional, Rawlinson, Tom, additional, Rea, David, additional, Rees, Byron, additional, Resuello-Dauti, Mila, additional, Reyes Pabon, Emilia, additional, Rhead, Sarah, additional, Riaz, Tawassal, additional, Ricamara, Marivic, additional, Richards, Alexander, additional, Richter, Alex, additional, Ritchie, Neil, additional, Ritchie, Adam J., additional, Robbins, Alexander J., additional, Roberts, Hannah, additional, Robinson, Ryan E., additional, Roche, Sophie, additional, Rollier, Christine, additional, Rose, Louisa, additional, Ross Russell, Amy L., additional, Rossouw, Lindie, additional, Royal, Simon, additional, Rudiansyah, Indra, additional, Ryalls, Kim, additional, Sabine, Charlotte, additional, Saich, Stephen, additional, Sale, Jessica C., additional, Salman, Ahmed M., additional, Salvador, Natalia, additional, Salvador, Stephannie, additional, Sampaio, Milla Dias, additional, Samson, Annette D., additional, Sanchez-Gonzalez, Amada, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Santos, Erika, additional, Santos Guerra, Mayara F.S., additional, Satti, Iman, additional, Saunders, Jack E., additional, Saunders, Caroline, additional, Sayed, Aakifah Bibi Arif, additional, Schim van der Loeff, Ina, additional, Schmid, Annina B., additional, Schofield, Ella, additional, Screaton, Gavin R., additional, Seddiqi, Samiullah, additional, Segireddy, Rameswara R., additional, Senger, Roberta, additional, Serrano, Sonia, additional, Shaik, Imam, additional, Sharpe, Hannah R., additional, Sharrocks, Katherine, additional, Shaw, Robert, additional, Shea, Adam, additional, Sheehan, Emma, additional, Shepherd, Amy, additional, Shiham, Farah, additional, Silk, Sarah E., additional, Silva-Reyes, Laura, additional, Silveira, Lidiana B. T.D., additional, Silveira, Mariana B.V., additional, Singh, Nisha, additional, Sinha, Jaisi, additional, Skelly, Donal T., additional, Smith, Daniel C., additional, Smith, Nick, additional, Smith, Holly E., additional, Smith, David J., additional, Smith, Catherine C., additional, Soares, Airanuédida S., additional, Solórzano, Carla, additional, Sorio, Guilherme L., additional, Sorley, Kim, additional, Sosa-Rodriguez, Tiffany, additional, Souza, Cinthia M.C.D.L., additional, Souza, Bruno S.D.F., additional, Souza, Alessandra R., additional, Souza Lopez, Thamyres, additional, Sowole, Luciana, additional, Spencer, Alexandra J., additional, Spoors, Louise, additional, Stafford, Lizzie, additional, Stamford, Imogen, additional, Stein, Ricardo, additional, Stockdale, Lisa, additional, Stockwell, Lisa V., additional, Strickland, Louise H., additional, Stuart, Arabella, additional, Sturdy, Ann, additional, Sutton, Natalina, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tanner, Rachel, additional, Taoushanis, Carol, additional, Tarr, Alexander W., additional, Tarrant, Richard, additional, Taylor, Keja, additional, Taylor, Ursula, additional, Taylor, Iona Jennifer, additional, Taylor, Justin, additional, te Water Naude, Rebecca, additional, Templeton, Kate, additional, Themistocleous, Yrene, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Kelly, additional, Thomas, Tonia M., additional, Thombrayil, Asha, additional, Thompson, Julia, additional, Thompson, Fawziyah, additional, Thompson, Ameeka, additional, Thompson, Amber, additional, Thompson, Kevin, additional, Thornton-Jones, Viv, additional, Thotusi, Larissa H.S., additional, Tighe, Patrick J., additional, Tinoco, Lygia Accioly, additional, Tiongson, Gerlynn Ferreras, additional, Tladinyane, Bonolo, additional, Tomasicchio, Michele, additional, Tomic, Adriana, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julia A., additional, Trillana, Gerry, additional, Trinham, Charlotte, additional, Trivett, Rose, additional, Truby, Adam, additional, Tsheko, Betty Lebogang, additional, Tubb, Philippa, additional, Turabi, Aadil, additional, Turner, Richard, additional, Turner, Cheryl, additional, Turner, Nicola, additional, Tyagi, Bhavya, additional, Ulaszewska, Marta, additional, Underwood, Benjamin R., additional, van Eck, Samual, additional, Varughese, Rachel, additional, Verbart, Dennis, additional, Verheul, Marije K., additional, Vichos, Iason, additional, Vieira, Taiane A., additional, Walker, Gemma, additional, Walker, Laura, additional, Wand, Matthew E., additional, Wardell, Theresa, additional, Warimwe, George M., additional, Warren, Sarah C., additional, Watkins, Bridget, additional, Watson, Marion E.E., additional, Watson, Ekaterina, additional, Webb, Stewart, additional, Webster, Angela, additional, Welch, Jessica, additional, Wellbelove, Zoe, additional, Wells, Jeanette H., additional, West, Alison J., additional, White, Beth, additional, White, Caroline, additional, White, Rachel, additional, Williams, Paul, additional, Williams, Rachel L., additional, Willingham, Silvia, additional, Winslow, Rebecca, additional, Woods, Danielle, additional, Woodyer, Mark, additional, Worth, Andrew T., additional, Wright, Danny, additional, Wroblewska, Marzena, additional, Yao, Andy, additional, Yim, Yee Ting Nicole, additional, Zambrano, Marina Bauer, additional, Zimmer, Rafael Leal, additional, Zizi, Dalila, additional, and Zuidewind, Peter, additional
- Published
- 2021
- Full Text
- View/download PDF
28. Intranasal Infection of Ferrets with SARS-CoV-2 as a Model for Asymptomatic Human Infection
- Author
-
Everett, Helen E., primary, Lean, Fabian Z. X., additional, Byrne, Alexander M. P., additional, van Diemen, Pauline M., additional, Rhodes, Shelley, additional, James, Joe, additional, Mollett, Benjamin, additional, Coward, Vivien J., additional, Skinner, Paul, additional, Warren, Caroline J., additional, Bewley, Kevin R., additional, Watson, Samantha, additional, Hurley, Shellene, additional, Ryan, Kathryn A., additional, Hall, Yper, additional, Simmons, Hugh, additional, Núñez, Alejandro, additional, Carroll, Miles W., additional, Brown, Ian H., additional, and Brookes, Sharon M., additional
- Published
- 2021
- Full Text
- View/download PDF
29. ChAdOx1 nCoV-19 protection against SARS-CoV-2 in rhesus macaque and ferret challenge models
- Author
-
Lambe, Teresa, primary, Spencer, Alexandra, additional, Thomas, Kelly, additional, Thomas, Stephen, additional, White, Andrew, additional, Humphries, Holly, additional, Wright, Daniel, additional, Thakur, Nazia, additional, Conceicao, Carina, additional, Alden, Leonie, additional, Allen, Lauren, additional, Aram, Marilyn, additional, Bewley, Kevin, additional, Brunt, Emily, additional, Brown, Phillip, additional, Cavell, Breeze, additional, Cobb, Rebecca, additional, Fotheringham, Susan, additional, Gilbride, Ciaran, additional, Harris, Debbie, additional, Ho, Catherine, additional, Hunter, Laura, additional, Kennard, Chelsea, additional, Leung, Stephanie, additional, Lucas, V, additional, Ngabo, Didier, additional, Ryan, Kathryn, additional, Sharpe, Hannah, additional, Sarfas, Charlotte, additional, Sibley, Laura, additional, Slack, Gillian, additional, Ulaszewska, Marta, additional, wand, Nadina, additional, Wiblin, Nathan, additional, Gleeson, Fergus, additional, Bailey, Dalan, additional, Sharpe, Sally, additional, Charlton, Sue, additional, Salguero, Francisco, additional, Carroll, Miles, additional, and Gilbert, Sarah, additional
- Published
- 2021
- Full Text
- View/download PDF
30. BNT162b2 Vaccination in People Over 80 Years of Age Induces Strong Humoral Immune Responses with Cross Neutralisation of P.1 Brazilian Variant
- Author
-
Parry, Helen Marie, primary, Tut, Gokhan, additional, Faustini, Sian, additional, Stephens, Christine, additional, Saunders, Philip, additional, Bentley, Christopher, additional, Hilyard, Katherine, additional, Brown, Kevin, additional, Amirthalingam, Gayatri, additional, Charlton, Sue, additional, Leung, Stephanie, additional, Chiplin, Emily, additional, Coombes, Naomi S., additional, Bewley, Kevin R., additional, Penn, Elizabeth J., additional, Rowe, Cathy, additional, Otter, Ashley, additional, Watts, Rosie, additional, D’Arcangelo, Silvia, additional, Hallis, Bassam, additional, Makin, Andrew, additional, Richter, Alex G., additional, Zuo, Jianmin, additional, and Moss, Paul, additional
- Published
- 2021
- Full Text
- View/download PDF
31. Reduced Neutralization of SARS-CoV-2 B.1.1.7 Variant from Naturally Acquired and Vaccine Induced Antibody Immunity
- Author
-
Supasa, Piyada, primary, Zhou, Daming, additional, Dejnirattisai, Wanwisa, additional, Liu, Chang, additional, Mentzer, Alexander J., additional, Ginn, Helen M., additional, Zhao, Yuguang, additional, Duyvesteyn, Helen ME, additional, Nutalai, Rungtiwa, additional, Tuekprakhon, Aekkachai, additional, Wang, Beibei, additional, Paesen, Guido C., additional, Slon-Campos, Jose, additional, Lopez-Camacho, Cesar, additional, Hallis, Bassam, additional, Coombes, Naomi, additional, Bewley, Kevin, additional, Charlton, Sue, additional, Walter, Thomas S., additional, Barnes, Eleanor, additional, Dunachie, Susanna, additional, Skelly, Donal, additional, Lumley, Sheila, additional, Baker, Natalie, additional, Shaik, Imam, additional, Humphries, Holly, additional, Godwin, Kerry, additional, Gent, Nick, additional, Sienkiewicz, Alex, additional, Dold, Christina, additional, Levin, Robert, additional, Dong, Tao, additional, Pollard, Andrew, additional, Knight, Julian, additional, Klenerman, Paul, additional, Crook, Derrick W., additional, Lambe, Teresa, additional, Clutterbuck, Elizabeth, additional, Bibi, Sagida, additional, Flaxman, Amy, additional, Bittaye, Mustapha, additional, Belij-rammerstorfer, Sandra, additional, Gilbert, Sarah C., additional, Hall, David R., additional, Williams, Mark A., additional, Paterson, Neil G., additional, James, William, additional, Carroll, Miles W., additional, Fry, Elizabeth E., additional, Mongkolspaya, Juthathip, additional, Ren, Jingshan, additional, Stuart, David I., additional, and Screaton, Gavin R., additional
- Published
- 2021
- Full Text
- View/download PDF
32. Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
- Author
-
Proud, Pamela C., primary, Tsitoura, Daphne, additional, Watson, Robert J., additional, Chua, Brendon Y., additional, Aram, Marilyn J., additional, Bewley, Kevin R., additional, Cavell, Breeze E., additional, Cobb, Rebecca, additional, Dowall, Stuart, additional, Fotheringham, Susan A., additional, Ho, Catherine M.K., additional, Lucas, Vanessa, additional, Ngabo, Didier, additional, Rayner, Emma, additional, Ryan, Kathryn A., additional, Slack, Gillian S., additional, Thomas, Stephen, additional, Wand, Nadina I., additional, Yeates, Paul, additional, Demaison, Christophe, additional, Zeng, Weiguang, additional, Holmes, Ian, additional, Jackson, David C., additional, Bartlett, Nathan W., additional, Mercuri, Francesca, additional, and Carroll, Miles W., additional
- Published
- 2021
- Full Text
- View/download PDF
33. Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
- Author
-
Voysey, Merryn, primary, Clemens, Sue Ann Costa, additional, Madhi, Shabir A, additional, Weckx, Lily Y, additional, Folegatti, Pedro M, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Baillie, Vicky L, additional, Barnabas, Shaun L, additional, Bhorat, Qasim E, additional, Bibi, Sagida, additional, Briner, Carmen, additional, Cicconi, Paola, additional, Collins, Andrea M, additional, Colin-Jones, Rachel, additional, Cutland, Clare L, additional, Darton, Thomas C, additional, Dheda, Keertan, additional, Duncan, Christopher J A, additional, Emary, Katherine R W, additional, Ewer, Katie J, additional, Fairlie, Lee, additional, Faust, Saul N, additional, Feng, Shuo, additional, Ferreira, Daniela M, additional, Finn, Adam, additional, Goodman, Anna L, additional, Green, Catherine M, additional, Green, Christopher A, additional, Heath, Paul T, additional, Hill, Catherine, additional, Hill, Helen, additional, Hirsch, Ian, additional, Hodgson, Susanne H C, additional, Izu, Alane, additional, Jackson, Susan, additional, Jenkin, Daniel, additional, Joe, Carina C D, additional, Kerridge, Simon, additional, Koen, Anthonet, additional, Kwatra, Gaurav, additional, Lazarus, Rajeka, additional, Lawrie, Alison M, additional, Lelliott, Alice, additional, Libri, Vincenzo, additional, Lillie, Patrick J, additional, Mallory, Raburn, additional, Mendes, Ana V A, additional, Milan, Eveline P, additional, Minassian, Angela M, additional, McGregor, Alastair, additional, Morrison, Hazel, additional, Mujadidi, Yama F, additional, Nana, Anusha, additional, O’Reilly, Peter J, additional, Padayachee, Sherman D, additional, Pittella, Ana, additional, Plested, Emma, additional, Pollock, Katrina M, additional, Ramasamy, Maheshi N, additional, Rhead, Sarah, additional, Schwarzbold, Alexandre V, additional, Singh, Nisha, additional, Smith, Andrew, additional, Song, Rinn, additional, Snape, Matthew D, additional, Sprinz, Eduardo, additional, Sutherland, Rebecca K, additional, Tarrant, Richard, additional, Thomson, Emma C, additional, Török, M Estée, additional, Toshner, Mark, additional, Turner, David P J, additional, Vekemans, Johan, additional, Villafana, Tonya L, additional, Watson, Marion E E, additional, Williams, Christopher J, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Pollard, Andrew J, additional, Aban, Marites, additional, Abayomi, Fatola, additional, Abeyskera, Kushala, additional, Aboagye, Jeremy, additional, Adam, Matthew, additional, Adams, Kirsty, additional, Adamson, James, additional, Adelaja, Yemi A., additional, Adewetan, Gbadebo, additional, Adlou, Syed, additional, Ahmed, Khatija, additional, Akhalwaya, Yasmeen, additional, Akhalwaya, Saajida, additional, Alcock, Andrew, additional, Ali, Aabidah, additional, Allen, Elizabeth R., additional, Allen, Lauren, additional, Almeida, Thamires C. D. S. C, additional, Alves, Mariana P.S., additional, Amorim, Fabio, additional, Andritsou, Foteini, additional, Anslow, Rachel, additional, Appleby, Matthew, additional, Arbe-Barnes, Edward H., additional, Ariaans, Mark P., additional, Arns, Beatriz, additional, Arruda, Laiana, additional, Azi, Paula, additional, Azi, Lorena, additional, Babbage, Gavin, additional, Bailey, Catherine, additional, Baker, Kenneth F., additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baldwin, Lisa, additional, Baleanu, Ioana, additional, Bandeira, Danieli, additional, Bara, Anna, additional, Barbosa, Marcella A.S., additional, Barker, Debbie, additional, Barlow, Gavin D., additional, Barnes, Eleanor, additional, Barr, Andrew S., additional, Barrett, Jordan R., additional, Barrett, Jessica, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beales, Emily, additional, Beckley, Rebecca, additional, Belij-Rammerstorfer, Sandra, additional, Bell, Jonathan, additional, Bellamy, Duncan, additional, Bellei, Nancy, additional, Belton, Sue, additional, Berg, Adam, additional, Bermejo, Laura, additional, Berrie, Eleanor, additional, Berry, Lisa, additional, Berzenyi, Daniella, additional, Beveridge, Amy, additional, Bewley, Kevin R., additional, Bexhell, Helen, additional, Bhikha, Sutika, additional, Bhorat, Asad E., additional, Bhorat, Zaheda E., additional, Bijker, Else, additional, Birch, Geeta, additional, Birch, Sarah, additional, Bird, Adam, additional, Bird, Olivia, additional, Bisnauthsing, Karen, additional, Bittaye, Mustapha, additional, Blackstone, Katherine, additional, Blackwell, Luke, additional, Bletchly, Heather, additional, Blundell, Caitlin L., additional, Blundell, Susannah R., additional, Bodalia, Pritesh, additional, Boettger, Bruno C., additional, Bolam, Emma, additional, Boland, Elena, additional, Bormans, Daan, additional, Borthwick, Nicola, additional, Bowring, Francesca, additional, Boyd, Amy, additional, Bradley, Penny, additional, Brenner, Tanja, additional, Brown, Phillip, additional, Brown, Claire, additional, Brown-O'Sullivan, Charlie, additional, Bruce, Scott, additional, Brunt, Emily, additional, Buchan, Ruaridh, additional, Budd, William, additional, Bulbulia, Yusuf A., additional, Bull, Melanie, additional, Burbage, Jamie, additional, Burhan, Hassan, additional, Burn, Aileen, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabera Puig, Ingrid, additional, Calderon, Gloria, additional, Calvert, Anna, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Cardoso, João R., additional, Carr, Melanie, additional, Carroll, Miles W., additional, Carson-Stevens, Andrew, additional, Carvalho, Yasmin de M., additional, Carvalho, José A.M., additional, Casey, Helen R., additional, Cashen, Paul, additional, Castro, Thais, additional, Castro, Lucia Carratala, additional, Cathie, Katrina, additional, Cavey, Ana, additional, Cerbino-Neto, José, additional, Chadwick, Jim, additional, Chapman, David, additional, Charlton, Sue, additional, Chelysheva, Irina, additional, Chester, Oliver, additional, Chita, Sunder, additional, Cho, Jee-Sun, additional, Cifuentes, Liliana, additional, Clark, Elizabeth, additional, Clark, Matthew, additional, Clarke, Andrea, additional, Clutterbuck, Elizabeth A., additional, Collins, Sarah L.K., additional, Conlon, Christopher P., additional, Connarty, Sean, additional, Coombes, Naomi, additional, Cooper, Cushla, additional, Cooper, Rachel, additional, Cornelissen, Lynne, additional, Corrah, Tumena, additional, Cosgrove, Catherine, additional, Cox, Tony, additional, Crocker, Wendy E.M., additional, Crosbie, Sarah, additional, Cullen, Lorraine, additional, Cullen, Dan, additional, Cunha, Debora R.M.F., additional, Cunningham, Christina, additional, Cuthbertson, Fiona C., additional, Da Guarda, Suzete N. Farias, additional, da Silva, Larissa P., additional, Damratoski, Brad E., additional, Danos, Zsofia, additional, Dantas, Maria T.D.C., additional, Darroch, Paula, additional, Datoo, Mehreen S., additional, Datta, Chandrabali, additional, Davids, Malika, additional, Davies, Sarah L., additional, Davies, Hannah, additional, Davis, Elizabeth, additional, Davis, Judith, additional, Davis, John, additional, De Nobrega, Maristela M.D., additional, De Oliveira Kalid, Lis Moreno, additional, Dearlove, David, additional, Demissie, Tesfaye, additional, Desai, Amisha, additional, Di Marco, Stefania, additional, Di Maso, Claudio, additional, Dinelli, Maria I.S., additional, Dinesh, Tanya, additional, Docksey, Claire, additional, Dold, Christina, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Dos Santos, Tannyth, additional, dos Santos, Thainá G., additional, Dos Santos, Erika Pachecho, additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Driver, Kimberley, additional, Drury, Ruth, additional, Dunachie, Susanna J., additional, Durham, Benjamin S., additional, Dutra, Lidiana, additional, Easom, Nicholas J.W., additional, van Eck, Samual, additional, Edwards, Mandy, additional, Edwards, Nick J., additional, El Muhanna, Omar M., additional, Elias, Sean C., additional, Elmore, Mike, additional, English, Marcus, additional, Esmail, Alisgair, additional, Essack, Yakub Moosa, additional, Farmer, Eoghan, additional, Farooq, Mutjaba, additional, Farrar, Madi, additional, Farrugia, Leonard, additional, Faulkner, Beverley, additional, Fedosyuk, Sofiya, additional, Felle, Sally, additional, Ferreira Da Silva, Carla, additional, Field, Samantha, additional, Fisher, Richard, additional, Flaxman, Amy, additional, Fletcher, James, additional, Fofie, Hazel, additional, Fok, Henry, additional, Ford, Karen J., additional, Fowler, Jamie, additional, Fraiman, Pedro H.A., additional, Francis, Emma, additional, Franco, Marilia M., additional, Frater, John, additional, Freire, Marilúcia S.M., additional, Fry, Samantha H., additional, Fudge, Sabrina, additional, Furze, Julie, additional, Fuskova, Michelle, additional, Galian-Rubio, Pablo, additional, Galiza, Eva, additional, Garlant, Harriet, additional, Gavrila, Madita, additional, Geddes, Ailsa, additional, Gibbons, Karyna A., additional, Gilbride, Ciaran, additional, Gill, Hardeep, additional, Glynn, Sharon, additional, Godwin, Kerry, additional, Gokani, Karishma, additional, Goldoni, Ursula Carvalho, additional, Goncalves, Maria, additional, Gonzalez, Isabela G.S., additional, Goodwin, Jayne, additional, Goondiwala, Amina, additional, Gordon-Quayle, Katherine, additional, Gorini, Giacomo, additional, Grab, Janet, additional, Gracie, Lara, additional, Greenland, Melanie, additional, Greenwood, Nicola, additional, Greffrath, Johann, additional, Groenewald, Marisa M., additional, Grossi, Leonardo, additional, Gupta, Gaurav, additional, Hackett, Mark, additional, Hallis, Bassam, additional, Hamaluba, Mainga, additional, Hamilton, Elizabeth, additional, Hamlyn, Joseph, additional, Hammersley, Daniel, additional, Hanrath, Aidan T., additional, Hanumunthadu, Brama, additional, Harris, Stephanie A., additional, Harris, Clair, additional, Harris, Tara, additional, Harrison, Thomas D., additional, Harrison, Daisy, additional, Hart, Thomas C., additional, Hartnell, Birgit, additional, Hassan, Shadin, additional, Haughney, John, additional, Hawkins, Sophia, additional, Hay, Jodie, additional, Head, Ian, additional, Henry, John, additional, Hermosin Herrera, Macarena, additional, Hettle, David B., additional, Hill, Jennifer, additional, Hodges, Gina, additional, Horne, Elizea, additional, Hou, Mimi M., additional, Houlihan, Catherine, additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Humphreys, Jonathan, additional, Humphries, Holly E., additional, Hurley, Katrina, additional, Huson, Claire, additional, Hyder-Wright, Angela, additional, Hyams, Catherine, additional, Ikram, Sabina, additional, Ishwarbhai, Alka, additional, Ivan, Monica, additional, Iveson, Poppy, additional, Iyer, Vidyashankara, additional, Jackson, Frederic, additional, De Jager, Jeanne, additional, Jaumdally, Shameem, additional, Jeffers, Helen, additional, Jesudason, Natasha, additional, Jones, Bryony, additional, Jones, Kathryn, additional, Jones, Elizabeth, additional, Jones, Christopher, additional, Jorge, Marianna Rocha, additional, Jose, Aylin, additional, Joshi, Amar, additional, Júnior, Eduardo A.M.S., additional, Kadziola, Joanne, additional, Kailath, Reshma, additional, Kana, Faeeza, additional, Karampatsas, Konstantinos, additional, Kasanyinga, Mwila, additional, Keen, Jade, additional, Kelly, Elizabeth J., additional, Kelly, Dearbhla M., additional, Kelly, Debbie, additional, Kelly, Sarah, additional, Kerr, David, additional, Kfouri, Renato de Ávila, additional, Khan, Liaquat, additional, Khozoee, Baktash, additional, Kidd, Sarah, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, Kinch, Patrick, additional, King, Lloyd D.W., additional, King, Thomas B., additional, Kingham, Lucy, additional, Klenerman, Paul, additional, Knapper, Francesca, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Lang, Matilda, additional, Lang, Gail, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Law, Rebecca, additional, Lazarus, Erica M., additional, Leach, Amanda, additional, Lees, Emily A., additional, Lemm, Nana-Marie, additional, Lessa, Alvaro, additional, Leung, Stephanie, additional, Li, Yuanyuan, additional, Lias, Amelia M., additional, Liatsikos, Kostas, additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Shuchang, additional, Liu, Xinxue, additional, Lloyd, Adam, additional, Lloyd, Stephanie, additional, Loew, Lisa, additional, Lopez Ramon, Raquel, additional, Lora, Leandro, additional, Lowthorpe, Vicki, additional, Luz, Kleber, additional, MacDonald, Jonathan C., additional, MacGregor, Gordon, additional, Madhavan, Meera, additional, Mainwaring, David O., additional, Makambwa, Edson, additional, Makinson, Rebecca, additional, Malahleha, Mookho, additional, Malamatsho, Ross, additional, Mallett, Garry, additional, Mansatta, Kushal, additional, Maoko, Takalani, additional, Mapetla, Katlego, additional, Marchevsky, Natalie G., additional, Marinou, Spyridoula, additional, Marlow, Emma, additional, Marques, Gabriela N., additional, Marriott, Paula, additional, Marshall, Richard P., additional, Marshall, Julia L., additional, Martins, Flávia J., additional, Masenya, Masebole, additional, Masilela, Mduduzi, additional, Masters, Shauna K., additional, Mathew, Moncy, additional, Matlebjane, Hosea, additional, Matshidiso, Kedidimetse, additional, Mazur, Olga, additional, Mazzella, Andrea, additional, McCaughan, Hugh, additional, McEwan, Joanne, additional, McGlashan, Joanna, additional, McInroy, Lorna, additional, McIntyre, Zoe, additional, McLenaghan, Daniela, additional, McRobert, Nicky, additional, McSwiggan, Steve, additional, Megson, Clare, additional, Mehdipour, Savviz, additional, Meijs, Wilma, additional, Mendonça, Renata N.Á., additional, Mentzer, Alexander J., additional, Mirtorabi, Neginsadat, additional, Mitton, Celia, additional, Mnyakeni, Sibusiso, additional, Moghaddas, Fiona, additional, Molapo, Kgaogelo, additional, Moloi, Mapule, additional, Moore, Maria, additional, Moraes-Pinto, M. Isabel, additional, Moran, Marni, additional, Morey, Ella, additional, Morgans, Róisín, additional, Morris, Susan, additional, Morris, Sheila, additional, Morris, Helen C., additional, Morselli, Franca, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Mottal, Lynelle, additional, Moultrie, Andrew, additional, Moya, Nathifa, additional, Mpelembue, Mushiya, additional, Msomi, Sibekezelo, additional, Mugodi, Yvonne, additional, Mukhopadhyay, Ekta, additional, Muller, Jilly, additional, Munro, Alasdair, additional, Munro, Claire, additional, Murphy, Sarah, additional, Mweu, Philomena, additional, Myasaki, Celia Hatsuko, additional, Naik, Gurudutt, additional, Naker, Kush, additional, Nastouli, Eleni, additional, Nazir, Abida, additional, Ndlovu, Bongani, additional, Neffa, Fabio, additional, Njenga, Cecilia, additional, Noal, Helena, additional, Noé, Andrés, additional, Novaes, Gabrielle, additional, Nugent, Fay L., additional, Nunes, Géssika, additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Odam, Miranda, additional, Oelofse, Suzette, additional, Oguti, Blanche, additional, Olchawski, Victoria, additional, Oldfield, Neil J., additional, Oliveira, Marianne G., additional, Oliveira, Catarina, additional, Oosthuizen, Angela, additional, O'Reilly, Paula, additional, Osborne, Piper, additional, Owen, David R.J., additional, Owen, Lydia, additional, Owens, Daniel, additional, Owino, Nelly, additional, Pacurar, Mihaela, additional, Paiva, Brenda V.B., additional, Palhares, Edna M.F., additional, Palmer, Susan, additional, Parkinson, Sivapriyai, additional, Parracho, Helena M.R.T., additional, Parsons, Karen, additional, Patel, Dipak, additional, Patel, Bhumika, additional, Patel, Faeezah, additional, Patel, Kelly, additional, Patrick-Smith, Maia, additional, Payne, Ruth O., additional, Peng, Yanchun, additional, Penn, Elizabeth J., additional, Pennington, Anna, additional, Peralta Alvarez, Marco Polo, additional, Perring, James, additional, Perry, Nicola, additional, Perumal, Rubeshan, additional, Petkar, Sahir, additional, Philip, Tricia, additional, Phillips, Daniel J., additional, Phillips, Jennifer, additional, Phohu, Mary Kgomotso, additional, Pickup, Lorinda, additional, Pieterse, Sonja, additional, Piper, Jo, additional, Pipini, Dimitra, additional, Plank, Mary, additional, Du Plessis, Joan, additional, Pollard, Samuel, additional, Pooley, Jennifer, additional, Pooran, Anil, additional, Poulton, Ian, additional, Powers, Claire, additional, Presa, Fernando B., additional, Price, David A., additional, Price, Vivien, additional, Primeira, Marcelo, additional, Proud, Pamela C., additional, Provstgaard-Morys, Samuel, additional, Pueschel, Sophie, additional, Pulido, David, additional, Quaid, Sheena, additional, Rabara, Ria, additional, Radford, Alexandra, additional, Radia, Kajal, additional, Rajapaska, Durga, additional, Rajeswaran, Thurkka, additional, Ramos, Alberto San Francisco, additional, Ramos Lopez, Fernando, additional, Rampling, Tommy, additional, Rand, Jade, additional, Ratcliffe, Helen, additional, Rawlinson, Tom, additional, Rea, David, additional, Rees, Byron, additional, Reiné, Jesús, additional, Resuello-Dauti, Mila, additional, Reyes Pabon, Emilia, additional, Ribiero, Carla M., additional, Ricamara, Marivic, additional, Richter, Alex, additional, Ritchie, Neil, additional, Ritchie, Adam J., additional, Robbins, Alexander J., additional, Roberts, Hannah, additional, Robinson, Ryan E., additional, Robinson, Hannah, additional, Rocchetti, Talita T., additional, Rocha, Beatriz Pinho, additional, Roche, Sophie, additional, Rollier, Christine, additional, Rose, Louisa, additional, Ross Russell, Amy L., additional, Rossouw, Lindie, additional, Royal, Simon, additional, Rudiansyah, Indra, additional, Ruiz, Sarah, additional, Saich, Stephen, additional, Sala, Claudia, additional, Sale, Jessica, additional, Salman, Ahmed M., additional, Salvador, Natalia, additional, Salvador, Stephannie, additional, Sampaio, Milla, additional, Samson, Annette D., additional, Sanchez-Gonzalez, Amada, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Santos, Erika, additional, Santos Guerra, Mayara F.S., additional, Satti, Iman, additional, Saunders, Jack E., additional, Saunders, Caroline, additional, Sayed, Aakifah, additional, Schim van der Loeff, Ina, additional, Schmid, Annina B., additional, Schofield, Ella, additional, Screaton, Gavin, additional, Seddiqi, Samiullah, additional, Segireddy, Rameswara R., additional, Senger, Roberta, additional, Serrano, Sonia, additional, Shah, Rajiv, additional, Shaik, Imam, additional, Sharpe, Hannah E., additional, Sharrocks, Katherine, additional, Shaw, Robert, additional, Shea, Adam, additional, Shepherd, Amy, additional, Shepherd, James G., additional, Shiham, Farah, additional, Sidhom, Emad, additional, Silk, Sarah E., additional, da Silva Moraes, Antonio Carlos, additional, Silva-Junior, Gilberto, additional, Silva-Reyes, Laura, additional, Silveira, Anderson D., additional, Silveira, Mariana B.V., additional, Sinha, Jaisi, additional, Skelly, Donal T., additional, Smith, Daniel C., additional, Smith, Nick, additional, Smith, Holly E., additional, Smith, David J., additional, Smith, Catherine C., additional, Soares, Airanuédida, additional, Soares, Tiago, additional, Solórzano, Carla, additional, Sorio, Guilherme L., additional, Sorley, Kim, additional, Sosa-Rodriguez, Tiffany, additional, Souza, Cinthia M.C.D.L., additional, Souza, Bruno S.D.F., additional, Souza, Alessandra R., additional, Spencer, Alexandra J., additional, Spina, Fernanda, additional, Spoors, Louise, additional, Stafford, Lizzie, additional, Stamford, Imogen, additional, Starinskij, Igor, additional, Stein, Ricardo, additional, Steven, Jill, additional, Stockdale, Lisa, additional, Stockwell, Lisa V., additional, Strickland, Louise H., additional, Stuart, Arabella C., additional, Sturdy, Ann, additional, Sutton, Natalina, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tanner, Rachel, additional, Taoushanis, Carol, additional, Tarr, Alexander W., additional, Taylor, Keja, additional, Taylor, Ursula, additional, Taylor, Iona Jennifer, additional, Taylor, Justin, additional, te Water Naude, Rebecca, additional, Themistocleous, Yrene, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Kelly, additional, Thomas, Tonia M., additional, Thombrayil, Asha, additional, Thompson, Fawziyah, additional, Thompson, Amber, additional, Thompson, Kevin, additional, Thompson, Ameeka, additional, Thomson, Julia, additional, Thornton-Jones, Viv, additional, Tighe, Patrick J., additional, Tinoco, Lygia Accioly, additional, Tiongson, Gerlynn, additional, Tladinyane, Bonolo, additional, Tomasicchio, Michele, additional, Tomic, Adriana, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julia, additional, Trillana, Gerry, additional, Trinham, Charlotte, additional, Trivett, Rose, additional, Truby, Adam, additional, Tsheko, Betty Lebogang, additional, Turabi, Aadil, additional, Turner, Richard, additional, Turner, Cheryl, additional, Ulaszewska, Marta, additional, Underwood, Benjamin R., additional, Varughese, Rachel, additional, Verbart, Dennis, additional, Verheul, Marije, additional, Vichos, Iason, additional, Vieira, Taiane, additional, Waddington, Claire S., additional, Walker, Laura, additional, Wallis, Erica, additional, Wand, Matthew, additional, Warbick, Deborah, additional, Wardell, Theresa, additional, Warimwe, George, additional, Warren, Sarah C., additional, Watkins, Bridget, additional, Watson, Ekaterina, additional, Webb, Stewart, additional, Webb-Bridges, Alice, additional, Webster, Angela, additional, Welch, Jessica, additional, Wells, Jeanette, additional, West, Alison, additional, White, Caroline, additional, White, Rachel, additional, Williams, Paul, additional, Williams, Rachel L., additional, Winslow, Rebecca, additional, Woodyer, Mark, additional, Worth, Andrew T., additional, Wright, Danny, additional, Wroblewska, Marzena, additional, Yao, Andy, additional, Zimmer, Rafael, additional, Zizi, Dalila, additional, and Zuidewind, Peter, additional
- Published
- 2021
- Full Text
- View/download PDF
34. Immunological and pathological outcomes of SARS-CoV-2 challenge after formalin-inactivated vaccine immunisation of ferrets and rhesus macaques
- Author
-
Bewley, Kevin R., primary, Gooch, Karen, additional, Thomas, Kelly M., additional, Longet, Stephanie, additional, Wiblin, Nathan, additional, Hunter, Laura, additional, Chan, Kin, additional, Brown, Phillip, additional, Russell, Rebecca A., additional, Ho, Catherine, additional, Slack, Gillian, additional, Humphries, Holly E., additional, Alden, Leonie, additional, Allen, Lauren, additional, Aram, Marilyn, additional, Baker, Natalie, additional, Brunt, Emily, additional, Cobb, Rebecca, additional, Fotheringham, Susan, additional, Harris, Debbie, additional, Kennard, Chelsea, additional, Leung, Stephanie, additional, Ryan, Kathryn, additional, Tolley, Howard, additional, Wand, Nadina, additional, White, Andrew, additional, Sibley, Laura, additional, Sarfas, Charlotte, additional, Pearson, Geoff, additional, Rayner, Emma, additional, Xue, Xiaochao, additional, Lambe, Teresa, additional, Charlton, Sue, additional, Gilbert, Sarah, additional, Sattentau, Quentin J., additional, Gleeson, Fergus, additional, Hall, Yper, additional, Funnell, Simon, additional, Sharpe, Sally, additional, Salguero, Francisco J., additional, Gorringe, Andrew, additional, and Carroll, Miles, additional
- Published
- 2020
- Full Text
- View/download PDF
35. Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial
- Author
-
Ramasamy, Maheshi N, primary, Minassian, Angela M, additional, Ewer, Katie J, additional, Flaxman, Amy L, additional, Folegatti, Pedro M, additional, Owens, Daniel R, additional, Voysey, Merryn, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Babbage, Gavin, additional, Belij-Rammerstorfer, Sandra, additional, Berry, Lisa, additional, Bibi, Sagida, additional, Bittaye, Mustapha, additional, Cathie, Katrina, additional, Chappell, Harry, additional, Charlton, Sue, additional, Cicconi, Paola, additional, Clutterbuck, Elizabeth A, additional, Colin-Jones, Rachel, additional, Dold, Christina, additional, Emary, Katherine R W, additional, Fedosyuk, Sofiya, additional, Fuskova, Michelle, additional, Gbesemete, Diane, additional, Green, Catherine, additional, Hallis, Bassam, additional, Hou, Mimi M, additional, Jenkin, Daniel, additional, Joe, Carina C D, additional, Kelly, Elizabeth J, additional, Kerridge, Simon, additional, Lawrie, Alison M, additional, Lelliott, Alice, additional, Lwin, May N, additional, Makinson, Rebecca, additional, Marchevsky, Natalie G, additional, Mujadidi, Yama, additional, Munro, Alasdair P S, additional, Pacurar, Mihaela, additional, Plested, Emma, additional, Rand, Jade, additional, Rawlinson, Thomas, additional, Rhead, Sarah, additional, Robinson, Hannah, additional, Ritchie, Adam J, additional, Ross-Russell, Amy L, additional, Saich, Stephen, additional, Singh, Nisha, additional, Smith, Catherine C, additional, Snape, Matthew D, additional, Song, Rinn, additional, Tarrant, Richard, additional, Themistocleous, Yrene, additional, Thomas, Kelly M, additional, Villafana, Tonya L, additional, Warren, Sarah C, additional, Watson, Marion E E, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Faust, Saul N, additional, Pollard, Andrew J, additional, Aboagye, Jeremy, additional, Adams, Kelly, additional, Ali, Aabidah, additional, Allen, Elizabeth R., additional, Allen, Lauren, additional, Allison, Jennifer L., additional, Andritsou, Foteini, additional, Anslow, Rachel, additional, Arbe-Barnes, Edward H., additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baleanu, Ioana, additional, Barker, Debbie, additional, Barnes, Eleanor, additional, Barrett, Jordan R., additional, Barrett, Kelly, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beckley, Rebecca, additional, Bellamy, Duncan, additional, Berg, Adam, additional, Bermejo, Laura, additional, Berrie, Eleanor, additional, Beveridge, Amy, additional, Bewley, Kevin, additional, Bijker, Else M., additional, Birch, Geeta, additional, Blackwell, Luke, additional, Bletchly, Heather, additional, Blundell, Caitlin L., additional, Blundell, Susannah R., additional, Bolam, Emma, additional, Boland, Elena, additional, Bormans, Daan, additional, Borthwick, Nicola, additional, Boukas, Konstantinos, additional, Bower, Thomas, additional, Bowring, Francesca, additional, Boyd, Amy, additional, Brenner, Tanja, additional, Brown, Phillip, additional, Brown-O'Sullivan, Charlie, additional, Bruce, Scott, additional, Brunt, Emily, additional, Burbage, Jamie, additional, Burgoyne, Joshua, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabera Puig, Ingrid, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Carr, Melanie, additional, Carroll, Miles W., additional, Cashen, Paul, additional, Cavey, Ana, additional, Chadwick, Jim, additional, Challis, Ruth, additional, Chapman, David, additional, Charles, David, additional, Chelysheva, Irina, additional, Cho, Jee-Sun, additional, Cifuentes, Liliana, additional, Clark, Elizabeth, additional, Collins, Sarah, additional, Conlon, Christopher P., additional, Coombes, Naomi S., additional, Cooper, Rachel, additional, Cooper, Cushla, additional, Crocker, Wendy E.M., additional, Crosbie, Sarah, additional, Cullen, Dan, additional, Cunningham, Christina, additional, Cuthbertson, Fiona, additional, Datoo, Brad E., additional, Dando, Lynne, additional, Datoo, Mehreen S., additional, Datta, Chandrabali, additional, Davies, Hannah, additional, Davies, Sarah, additional, Davis, Elizabeth J., additional, Davis, Judith, additional, Dearlove, David, additional, Demissie, Tesfaye, additional, Di Marco, Stefania, additional, Di Maso, Claudio, additional, DiTirro, Danielle, additional, Docksey, Claire, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Drury, Ruth E., additional, Dunachie, Susanna J., additional, Edwards, Christopher J., additional, Edwards, Nick J., additional, El Muhanna, Omar, additional, Elias, Sean C., additional, Elliott, Ryan S., additional, Elmore, Michael J., additional, English, Marcus Rex, additional, Felle, Sally, additional, Feng, Shuo, additional, Ferreira Da Silva, Carla, additional, Field, Samantha, additional, Fisher, Richard, additional, Fixmer, Carine, additional, Ford, Karen J., additional, Fowler, Jamie, additional, Francis, Emma, additional, Frater, John, additional, Furze, Julie, additional, Galian-Rubio, Pablo, additional, Galloway, Celine, additional, Garlant, Harriet, additional, Gavrila, Madita, additional, Gibbons, Felicity, additional, Gibbons, Karyna, additional, Gilbride, Ciaran, additional, Gill, Hardeep, additional, Godwin, Kerry, additional, Gordon-Quayle, Katherine, additional, Gorini, Giacomo, additional, Goulston, Lyndsey, additional, Grabau, Caroline, additional, Gracie, Lara, additional, Graham, Nichola, additional, Greenwood, Nicola, additional, Griffiths, Oliver, additional, Gupta, Gaurav, additional, Hamilton, Elizabeth, additional, Hanumunthadu, Brama, additional, Harris, Stephanie A., additional, Harris, Tara, additional, Harrison, Daisy, additional, Hart, Thomas C., additional, Hartnell, Birgit, additional, Haskell, Louise, additional, Hawkins, Sophia, additional, Henry, John Aaron, additional, Hermosin Herrera, Macarena, additional, Hill, David, additional, Hill, Jennifer, additional, Hodges, Gina, additional, Hodgson, Susanne H.C., additional, Horton, Katie L., additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Howes, Jessica, additional, Huang, Ben, additional, Humphreys, Jonathan, additional, Humphries, Holly E., additional, Iveson, Poppy, additional, Jackson, Frederic, additional, Jackson, Susan, additional, Jauregui, Sam, additional, Jeffers, Helen, additional, Jones, Bryony, additional, Jones, Christine E., additional, Jones, Elizabeth, additional, Jones, Kathryn, additional, Joshi, Amar, additional, Kailath, Reshma, additional, Keen, Jade, additional, Kelly, Dearbhla M., additional, Kelly, Sarah, additional, Kelly, Debbie, additional, Kerr, David, additional, Khan, Liaquat, additional, Khozoee, Baktash, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, King, Lloyd D.W., additional, King, Thomas B., additional, Kingham, Lucy, additional, Klenerman, Paul, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Lang, Gail, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Law, Rebecca, additional, Lee, Arlene, additional, Lee, Kim Y.N., additional, Lees, Emily A., additional, Leung, Stephanie, additional, Li, Yuanyuan, additional, Lias, Amelia M., additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Shuchang, additional, Liu, Xinxue, additional, Lloyd, Stephanie, additional, Loew, Lisa, additional, Lopez Ramon, Raquel, additional, Madhavan, Meera, additional, Mainwaring, David O., additional, Mallett, Garry, additional, Mansatta, Kushal, additional, Marinou, Spyridoula, additional, Marius, Phedra, additional, Marlow, Emma, additional, Marriott, Paula, additional, Marshall, Julia L., additional, Martin, Jane, additional, Masters, Shauna, additional, McEwan, Joanne, additional, McGlashan, Joanna L., additional, McInroy, Lorna, additional, McRobert, Nicky, additional, Megson, Clare, additional, Mentzer, Alexander J., additional, Mirtorabi, Neginsadat, additional, Mitton, Celia, additional, Moore, Maria, additional, Moran, Marni, additional, Morey, Ella, additional, Morgans, Róisín, additional, Morris, Susan J., additional, Morrison, Hazel Morrison, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Moya, Nathifa A., additional, Mukhopadhyay, Ekta, additional, Muller, Jilly, additional, Munro, Claire, additional, Murphy, Sarah, additional, Mweu, Philomena, additional, Noé, Andrés, additional, Nugent, Fay L., additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Oguti, Blanché, additional, Olchawski, Victoria, additional, Oliveira, Catarina, additional, O'Reilly, Peter John, additional, Osborne, Piper, additional, Owen, Lydia, additional, Owino, Nelly, additional, Papageorgiou, Panagiotis, additional, Parracho, Helena, additional, Parsons, Karen, additional, Patel, Bhumika, additional, Patrick-Smith, Maia, additional, Peng, Yanchun, additional, Penn, Elizabeth J., additional, Peralta-Alvarez, Marco Polo, additional, Perring, James, additional, Petropoulos, Christos, additional, Phillips, Daniel J., additional, Pipini, Dimitra, additional, Pollard, Samuel, additional, Poulton, Ian, additional, Pratt, Danny, additional, Presland, Laura, additional, Proud, Pamela C., additional, Provstgaard-Morys, Samuel, additional, Pueschel, Sophie, additional, Pulido, David, additional, Rabara, Ria, additional, Radia, Kajal, additional, Rajapaska, Durga, additional, Ramos Lopez, Fernando, additional, Ratcliffe, Helen, additional, Rayhan, Sara, additional, Rees, Byron, additional, Reyes Pabon, Emilia, additional, Roberts, Hannah, additional, Robertson, Isla, additional, Roche, Sophie, additional, Rollier, Christine S., additional, Romani, Rossana, additional, Rose, Zoe, additional, Rudiansyah, Indra, additional, Sabheha, Sabeha, additional, Salvador, Stephannie, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Satti, Iman, additional, Sayce, Chloe, additional, Schmid, Annina B., additional, Schofield, Ella, additional, Screaton, Gavin, additional, Sedik, Cynthia, additional, Seddiqi, Samiullah, additional, Segireddy, Rameswara R., additional, Selby, Beatrice, additional, Shaik, Imam, additional, Sharpe, Hannah R., additional, Shaw, Robert, additional, Shea, Adam, additional, Silk, Sarah, additional, Silva-Reyes, Laura, additional, Skelly, Donal T., additional, Smith, David J., additional, Smith, Daniel C., additional, Smith, Nicholas, additional, Spencer, Alexandra J., additional, Spoors, Louise, additional, Stafford, Elizabeth, additional, Stamford, Imogen, additional, Stockdale, Lisa, additional, Stockley, David, additional, Stockwell, Lisa V., additional, Stokes, Matthew, additional, Strickland, Louise H., additional, Stuart, Arabella, additional, Sulaiman, Sulaiman, additional, Summerton, Eloise, additional, Swash, Zoe, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tanner, Rachel, additional, Taylor, Iona, additional, Taylor, Keja, additional, Taylor, Ursula, additional, te Water Naude, Rebecca, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Tonia M., additional, Thompson, Amber, additional, Thompson, Kevin, additional, Thornton-Jones, Viv, additional, Tinh, Lan, additional, Tomic, Adriana, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julian A., additional, Truby, Adam, additional, Turner, Cheryl, additional, Turner, Richard, additional, Ulaszewska, Marta, additional, Varughese, Rachel, additional, Verbart, Dennis, additional, Verheul, Marije K., additional, Vichos, Iason, additional, Walker, Laura, additional, Wand, Matthew E., additional, Watkins, Bridget, additional, Welch, Jessica, additional, West, Alison J., additional, White, Caroline, additional, White, Rachel, additional, Williams, Paul, additional, Woodyer, Mark, additional, Worth, Andrew T., additional, Wright, Daniel, additional, Wrin, Terri, additional, Yao, Xin Li, additional, Zbarcea, Diana-Andreea, additional, and Zizi, Dalila, additional
- Published
- 2020
- Full Text
- View/download PDF
36. Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism
- Author
-
Moore, Shona C., primary, Penrice-Randal, Rebekah, additional, Alruwaili, Muhannad, additional, Randle, Nadine, additional, Armstrong, Stuart, additional, Hartley, Catherine, additional, Haldenby, Sam, additional, Dong, Xiaofeng, additional, Alrezaihi, Abdulrahman, additional, Almsaud, Mai, additional, Bentley, Eleanor, additional, Clark, Jordan, additional, García-Dorival, Isabel, additional, Gilmore, Paul, additional, Han, Ximeng, additional, Jones, Benjamin, additional, Luu, Lisa, additional, Sharma, Parul, additional, Shawli, Ghada, additional, Sun, Yani, additional, Zhao, Qin, additional, Pullan, Steven T., additional, Carter, Daniel P., additional, Bewley, Kevin, additional, Dunning, Jake, additional, Zhou, En-min, additional, Solomon, Tom, additional, Beadsworth, Michael, additional, Cruise, James, additional, Crook, Derrick W., additional, Matthews, David A., additional, Davidson, Andrew D., additional, Mahmood, Zana, additional, Aljabr, Waleed, additional, Druce, Julian, additional, Vipond, Richard, additional, Ng, Lisa, additional, Renia, Laurent, additional, Openshaw, Peter J. M., additional, Baillie, J. Kenneth, additional, Carroll, Miles W., additional, Stewart, James, additional, Darby, Alistair, additional, Semple, Malcolm, additional, Turtle, Lance, additional, and Hiscox, Julian A., additional
- Published
- 2020
- Full Text
- View/download PDF
37. Prophylactic intranasal administration of a TLR2 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
- Author
-
Proud, Pamela C., primary, Tsitoura, Daphne, additional, Watson, Robert J., additional, Chua, Brendon Y, additional, Aram, Marilyn J., additional, Bewley, Kevin R., additional, Cavell, Breeze E., additional, Cobb, Rebecca, additional, Dowall, Stuart, additional, Fotheringham, Susan A., additional, Ho, Catherine M. K., additional, Lucas, Vanessa, additional, Ngabo, Didier, additional, Rayner, Emma, additional, Ryan, Kathryn A., additional, Slack, Gillian S., additional, Thomas, Stephen, additional, Wand, Nadina I., additional, Yeates, Paul, additional, Demaison, Christophe, additional, Jackson, David C., additional, Bartlett, Nathan W., additional, Mercuri, Francesca, additional, and Carroll, Miles W., additional
- Published
- 2020
- Full Text
- View/download PDF
38. Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19
- Author
-
Salguero, Francisco J., primary, White, Andrew D., additional, Slack, Gillian S., additional, Fotheringham, Susan A., additional, Bewley, Kevin R., additional, Gooch, Karen E., additional, Longet, Stephanie, additional, Humphries, Holly E., additional, Watson, Robert J., additional, Hunter, Laura, additional, Ryan, Kathryn A., additional, Hall, Yper, additional, Sibley, Laura, additional, Sarfas, Charlotte, additional, Allen, Lauren, additional, Aram, Marilyn, additional, Brunt, Emily, additional, Brown, Phillip, additional, Buttigieg, Karen R., additional, Cavell, Breeze E., additional, Cobb, Rebecca, additional, Coombes, Naomi S., additional, Daykin-Pont, Owen, additional, Elmore, Michael J., additional, Gkolfinos, Konstantinos, additional, Godwin, Kerry J., additional, Gouriet, Jade, additional, Halkerston, Rachel, additional, Harris, Debbie J., additional, Hender, Thomas, additional, Ho, Catherine M.K., additional, Kennard, Chelsea L., additional, Knott, Daniel, additional, Leung, Stephanie, additional, Lucas, Vanessa, additional, Mabbutt, Adam, additional, Morrison, Alexandra L., additional, Ngabo, Didier, additional, Paterson, Jemma, additional, Penn, Elizabeth J., additional, Pullan, Steve, additional, Taylor, Irene, additional, Tipton, Tom, additional, Thomas, Stephen, additional, Tree, Julia A., additional, Turner, Carrie, additional, Wand, Nadina, additional, Wiblin, Nathan R., additional, Charlton, Sue, additional, Hallis, Bassam, additional, Pearson, Geoffrey, additional, Rayner, Emma L., additional, Nicholson, Andrew G., additional, Funnell, Simon G., additional, Dennis, Mike J., additional, Gleeson, Fergus V., additional, Sharpe, Sally, additional, and Carroll, Miles W., additional
- Published
- 2020
- Full Text
- View/download PDF
39. Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
- Author
-
Huo, Jiandong, primary, Zhao, Yuguang, additional, Ren, Jingshan, additional, Zhou, Daming, additional, Duyvesteyn, Helen M.E., additional, Ginn, Helen M., additional, Carrique, Loic, additional, Malinauskas, Tomas, additional, Ruza, Reinis R., additional, Shah, Pranav N.M., additional, Tan, Tiong Kit, additional, Rijal, Pramila, additional, Coombes, Naomi, additional, Bewley, Kevin R., additional, Tree, Julia A., additional, Radecke, Julika, additional, Paterson, Neil G., additional, Supasa, Piyada, additional, Mongkolsapaya, Juthathip, additional, Screaton, Gavin R., additional, Carroll, Miles, additional, Townsend, Alain, additional, Fry, Elizabeth E., additional, Owens, Raymond J., additional, and Stuart, David I., additional
- Published
- 2020
- Full Text
- View/download PDF
40. Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
- Author
-
Folegatti, Pedro M, primary, Ewer, Katie J, additional, Aley, Parvinder K, additional, Angus, Brian, additional, Becker, Stephan, additional, Belij-Rammerstorfer, Sandra, additional, Bellamy, Duncan, additional, Bibi, Sagida, additional, Bittaye, Mustapha, additional, Clutterbuck, Elizabeth A, additional, Dold, Christina, additional, Faust, Saul N, additional, Finn, Adam, additional, Flaxman, Amy L, additional, Hallis, Bassam, additional, Heath, Paul, additional, Jenkin, Daniel, additional, Lazarus, Rajeka, additional, Makinson, Rebecca, additional, Minassian, Angela M, additional, Pollock, Katrina M, additional, Ramasamy, Maheshi, additional, Robinson, Hannah, additional, Snape, Matthew, additional, Tarrant, Richard, additional, Voysey, Merryn, additional, Green, Catherine, additional, Douglas, Alexander D, additional, Hill, Adrian V S, additional, Lambe, Teresa, additional, Gilbert, Sarah C, additional, Pollard, Andrew J, additional, Aboagye, Jeremy, additional, Adams, Kelly, additional, Ali, Aabidah, additional, Allen, Elizabeth, additional, Allison, Jennifer L., additional, Anslow, Rachel, additional, Arbe-Barnes, Edward H., additional, Babbage, Gavin, additional, Baillie, Kenneth, additional, Baker, Megan, additional, Baker, Natalie, additional, Baker, Philip, additional, Baleanu, Ioana, additional, Ballaminut, Juliana, additional, Barnes, Eleanor, additional, Barrett, Jordan, additional, Bates, Louise, additional, Batten, Alexander, additional, Beadon, Kirsten, additional, Beckley, Rebecca, additional, Berrie, Eleanor, additional, Berry, Lisa, additional, Beveridge, Amy, additional, Bewley, Kevin R., additional, Bijker, Else Margreet, additional, Bingham, Tracey, additional, Blackwell, Luke, additional, Blundell, Caitlin L., additional, Bolam, Emma, additional, Boland, Elena, additional, Borthwick, Nicola, additional, Bower, Thomas, additional, Boyd, Amy, additional, Brenner, Tanja, additional, Bright, Philip D., additional, Brown-O'Sullivan, Charlie, additional, Brunt, Emily, additional, Burbage, Jamie, additional, Burge, Sharon, additional, Buttigieg, Karen R., additional, Byard, Nicholas, additional, Cabera Puig, Ingrid, additional, Calvert, Anna, additional, Camara, Susana, additional, Cao, Michelangelo, additional, Cappuccini, Federica, additional, Carr, Melanie, additional, Carroll, Miles W., additional, Carter, Victoria, additional, Cathie, Katrina, additional, Challis, Ruth J., additional, Charlton, Sue, additional, Chelysheva, Irina, additional, Cho, Jee-Sun, additional, Cicconi, Paola, additional, Cifuentes, Liliana, additional, Clark, Helen, additional, Clark, Elizabeth, additional, Cole, Tom, additional, Colin-Jones, Rachel, additional, Conlon, Christopher P., additional, Cook, Aislinn, additional, Coombes, Naomi S., additional, Cooper, Rachel, additional, Cosgrove, Catherine A., additional, Coy, Karen, additional, Crocker, Wendy E.M., additional, Cunningham, Christina J., additional, Damratoski, Brad E., additional, Dando, Lynne, additional, Datoo, Mehreen S., additional, Davies, Hannah, additional, De Graaf, Hans, additional, Demissie, Tesfaye, additional, Di Maso, Claudio, additional, Dietrich, Isabelle, additional, Dong, Tao, additional, Donnellan, Francesca R., additional, Douglas, Naomi, additional, Downing, Charlotte, additional, Drake, Jonathan, additional, Drake-Brockman, Rachael, additional, Drury, Ruth Elizabeth, additional, Dunachie, Susanna Jane, additional, Edwards, Nick J., additional, Edwards, Frances D.L., additional, Edwards, Chris J., additional, Elias, Sean C., additional, Elmore, Michael J., additional, Emary, Katherine R.W., additional, English, Marcus Rex, additional, Fagerbrink, Susanne, additional, Felle, Sally, additional, Feng, Shuo, additional, Field, Samantha, additional, Fixmer, Carine, additional, Fletcher, Clare, additional, Ford, Karen J., additional, Fowler, Jamie, additional, Fox, Polly, additional, Francis, Emma, additional, Frater, John, additional, Furze, Julie, additional, Fuskova, Michelle, additional, Galiza, Eva, additional, Gbesemete, Diane, additional, Gilbride, Ciaran, additional, Godwin, Kerry, additional, Gorini, Giacomo, additional, Goulston, Lyndsey, additional, Grabau, Caroline, additional, Gracie, Lara, additional, Gray, Zoe, additional, Guthrie, Lucy Belle, additional, Hackett, Mark, additional, Halwe, Sandro, additional, Hamilton, Elizabeth, additional, Hamlyn, Joseph, additional, Hanumunthadu, Brama, additional, Harding, Irasha, additional, Harris, Stephanie A., additional, Harris, Andrew, additional, Harrison, Daisy, additional, Harrison, Clare, additional, Hart, Thomas C., additional, Haskell, Louise, additional, Hawkins, Sophia, additional, Head, Ian, additional, Henry, John Aaron, additional, Hill, Jennifer, additional, Hodgson, Susanne H.C., additional, Hou, Mimi M., additional, Howe, Elizabeth, additional, Howell, Nicola, additional, Hutlin, Cecilia, additional, Ikram, Sabina, additional, Isitt, Catherine, additional, Iveson, Poppy, additional, Jackson, Susan, additional, Jackson, Frederic, additional, James, Sir William, additional, Jenkins, Megan, additional, Jones, Elizabeth, additional, Jones, Kathryn, additional, Jones, Christine E., additional, Jones, Bryony, additional, Kailath, Reshma, additional, Karampatsas, Konstantinos, additional, Keen, Jade, additional, Kelly, Sarah, additional, Kelly, Dearbhla, additional, Kerr, David, additional, Kerridge, Simon, additional, Khan, Liaquat, additional, Khan, Uzma, additional, Killen, Annabel, additional, Kinch, Jasmin, additional, King, Thomas B., additional, King, Lloyd, additional, King, Jade, additional, Kingham-Page, Lucy, additional, Klenerman, Paul, additional, Knapper, Francesca, additional, Knight, Julian C., additional, Knott, Daniel, additional, Koleva, Stanislava, additional, Kupke, Alexandra, additional, Larkworthy, Colin W., additional, Larwood, Jessica P.J., additional, Laskey, Anna, additional, Lawrie, Alison M., additional, Lee, Arlene, additional, Ngan Lee, Kim Yee, additional, Lees, Emily A, additional, Legge, Helen, additional, Lelliott, Alice, additional, Lemm, Nana-Marie, additional, Lias, Amelia M., additional, Linder, Aline, additional, Lipworth, Samuel, additional, Liu, Xinxue, additional, Liu, Shuchang, additional, Lopez Ramon, Raquel, additional, Lwin, May, additional, Mabesa, Francesca, additional, Madhavan, Meera, additional, Mallett, Garry, additional, Mansatta, Kushal, additional, Marcal, Ines, additional, Marinou, Spyridoula, additional, Marlow, Emma, additional, Marshall, Julia L., additional, Martin, Jane, additional, McEwan, Joanne, additional, McInroy, Lorna, additional, Meddaugh, Gretchen, additional, Mentzer, Alexander J., additional, Mirtorabi, Neginsadat, additional, Moore, Maria, additional, Moran, Edward, additional, Morey, Ella, additional, Morgan, Victoria, additional, Morris, Susan Jane, additional, Morrison, Hazel, additional, Morshead, Gertraud, additional, Morter, Richard, additional, Mujadidi, Yama F., additional, Muller, Jilly, additional, Munera-Huertas, Tatiana, additional, Munro, Claire, additional, Munro, Alasdair, additional, Murphy, Sarah, additional, Munster, Vincent J., additional, Mweu, Philomena, additional, Noé, Andrés, additional, Nugent, Fay L., additional, Nuthall, Elizabeth, additional, O'Brien, Katie, additional, O'Connor, Daniel, additional, Oguti, Blanché, additional, Oliver, Jennifer L., additional, Oliveira, Catarina, additional, O'Reilly, Peter John, additional, Osborn, Mairead, additional, Osborne, Piper, additional, Owen, Cathy, additional, Owens, Daniel, additional, Owino, Nelly, additional, Pacurar, Mihaela, additional, Parker, Kaye, additional, Parracho, Helena, additional, Patrick-Smith, Maia, additional, Payne, Victoria, additional, Pearce, Jennifer, additional, Peng, Yanchun, additional, Peralta Alvarez, Marco Polo, additional, Perring, James, additional, Pfafferott, Katja, additional, Pipini, Dimitra, additional, Plested, Emma, additional, Pluess-Hall, Helen, additional, Pollock, Katrina, additional, Poulton, Ian, additional, Presland, Laura, additional, Provstgaard-Morys, Samuel, additional, Pulido, David, additional, Radia, Kajal, additional, Ramos Lopez, Fernando, additional, Rand, Jade, additional, Ratcliffe, Helen, additional, Rawlinson, Thomas, additional, Rhead, Sarah, additional, Riddell, Amy, additional, Ritchie, Adam John, additional, Roberts, Hannah, additional, Robson, Joanna, additional, Roche, Sophie, additional, Rohde, Cornelius, additional, Rollier, Christine S., additional, Romani, Rossana, additional, Rudiansyah, Indra, additional, Saich, Stephen, additional, Sajjad, Sara, additional, Salvador, Stephannie, additional, Sanchez Riera, Lidia, additional, Sanders, Helen, additional, Sanders, Katherine, additional, Sapaun, Shari, additional, Sayce, Chloe, additional, Schofield, Ella, additional, Screaton, Gavin, additional, Selby, Beatrice, additional, Semple, Calum, additional, Sharpe, Hannah R., additional, Shaik, Imam, additional, Shea, Adam, additional, Shelton, Holly, additional, Silk, Sarah, additional, Silva-Reyes, Laura, additional, Skelly, Donal T., additional, Smee, Heather, additional, Smith, Catherine C., additional, Smith, David J., additional, Song, Rinn, additional, Spencer, Alexandra J., additional, Stafford, Elizabeth, additional, Steele, Amy, additional, Stefanova, Elena, additional, Stockdale, Lisa, additional, Szigeti, Anna, additional, Tahiri-Alaoui, Abdessamad, additional, Tait, Moira, additional, Talbot, Helen, additional, Tanner, Rachel, additional, Taylor, Iona Jennifer, additional, Taylor, Victoria, additional, Te Water Naude, Rebecca, additional, Thakur, Nazia, additional, Themistocleous, Yrene, additional, Themistocleous, Andreas, additional, Thomas, Merin, additional, Thomas, Tonia M., additional, Thompson, Amber, additional, Thomson-Hill, Samantha, additional, Tomlins, Jennifer, additional, Tonks, Susan, additional, Towner, James, additional, Tran, Nguyen, additional, Tree, Julia A., additional, Truby, Adam, additional, Turkentine, Kate, additional, Turner, Cheryl, additional, Turner, Nicola, additional, Turner, Sally, additional, Tuthill, Toby, additional, Ulaszewska, Marta, additional, Varughese, Rachel, additional, Van Doremalen, Neeltje, additional, Veighey, Kristin, additional, Verheul, Marije K., additional, Vichos, Iason, additional, Vitale, Elia, additional, Walker, Laura, additional, Watson, Marion E.E., additional, Welham, Benjamin, additional, Wheat, Julie, additional, White, Caroline, additional, White, Rachel, additional, Worth, Andrew T., additional, Wright, Danny, additional, Wright, Suzie, additional, Yao, Xin Li, additional, and Yau, Yasmine, additional
- Published
- 2020
- Full Text
- View/download PDF
41. Dose-dependent response to infection with SARS-CoV-2 in the ferret model: evidence of protection to re-challenge
- Author
-
Ryan, Kathryn A., primary, Bewley, Kevin R., additional, Fotheringham, Susan A., additional, Brown, Phillip, additional, Hall, Yper, additional, Marriott, Anthony C., additional, Tree, Julia A., additional, Allen, Lauren, additional, Aram, Marilyn J., additional, Brunt, Emily, additional, Buttigieg, Karen R., additional, Cavell, Breeze E., additional, Carter, Daniel P., additional, Cobb, Rebecca, additional, Coombes, Naomi S., additional, Godwin, Kerry J., additional, Gooch, Karen E., additional, Gouriet, Jade, additional, Halkerston, Rachel, additional, Harris, Debbie J., additional, Humphries, Holly E., additional, Hunter, Laura, additional, Ho, Catherine M. K., additional, Kennard, Chelsea L., additional, Leung, Stephanie, additional, Ngabo, Didier, additional, Osman, Karen L., additional, Paterson, Jemma, additional, Penn, Elizabeth J., additional, Pullan, Steven T., additional, Rayner, Emma, additional, Slack, Gillian S., additional, Steeds, Kimberley, additional, Taylor, Irene, additional, Tipton, Tom, additional, Thomas, Stephen, additional, Wand, Nadina I., additional, Watson, Robert J., additional, Wiblin, Nathan R., additional, Charlton, Sue, additional, Hallis, Bassam, additional, Hiscox, Julian A., additional, Funnell, Simon, additional, Dennis, Mike J., additional, Whittaker, Catherine J., additional, Catton, Michael G., additional, Druce, Julian, additional, Salguero, Francisco J., additional, and Carroll, Miles W., additional
- Published
- 2020
- Full Text
- View/download PDF
42. Amplicon based MinION sequencing of SARS-CoV-2 and metagenomic characterisation of nasopharyngeal swabs from patients with COVID-19
- Author
-
Moore, Shona C., primary, Penrice-Randal, Rebekah, additional, Alruwaili, Muhannad, additional, Dong, Xiaofeng, additional, Pullan, Steven T., additional, Carter, Daniel P., additional, Bewley, Kevin, additional, Zhao, Qin, additional, Sun, Yani, additional, Hartley, Catherine, additional, Zhou, En-min, additional, Solomon, Tom, additional, Beadsworth, Michael B. J., additional, Cruise, James, additional, Bogaert, Debby, additional, Crook, Derrick W., additional, Matthews, David A., additional, Davidson, Andrew D., additional, Mahmood, Zana, additional, Aljabr, Waleed, additional, Druce, Julian, additional, Vipond, Richard T., additional, Ng, Lisa F. P., additional, Renia, Laurent, additional, Openshaw, Peter J. M., additional, Baillie, J. Kenneth, additional, Carroll, Miles W., additional, Semple, Malcolm G., additional, Turtle, Lance, additional, and Hiscox, Julian A., additional
- Published
- 2020
- Full Text
- View/download PDF
43. Nosocomial buffalopoxvirus infection, Karachi, Pakistan
- Author
-
Zafar, Afia, Swanepoel, Robert, Hewson, Roger, Nizam, Mazhar, Ahmed, Altaf, Husain, Akhtar, Grobbelaar, Antoinette, Bewley, Kevin, Mioulet, Valerie, Dowsett, Barry, Easterbrook, Linda, and Hasan, Rumina
- Subjects
Disease transmission -- Health aspects ,Cross infection -- Health aspects ,Nosocomial infections -- Health aspects - Abstract
During 5 months in 2004-2005, buffalopoxvirus infection, confirmed by virus isolation and limited nucleic acid sequencing, spread between 5 burns units in Karachi, Pakistan. The outbreak was related to movement [...]
- Published
- 2007
44. A black necrotic ulcer. (Case report)
- Author
-
Lawn, Stephen D, Planche, Timothy, Riley, Peter, Holwill, Stephen, Silman, Nigel, Bewley, Kevin, Rice, Philip, and Wansbrough-Jones, Mark H
- Subjects
Skin -- Ulcers ,Cowpox - Published
- 2003
45. Poliovirus type 1 in working stocks of typed human rhinoviruses. (Research letters)
- Author
-
Davies, Marc, Bruce, Christine, Bewley, Kevin, Outlaw, Mark, Mioulet, Valerie, Lloyd, Graham, and Clegg, Christopher
- Subjects
Poliovirus ,Virus research -- Contamination ,Rhinoviruses -- Contamination - Published
- 2003
46. Animal Models of Q Fever (Coxiella burnetii)
- Author
-
Bewley, Kevin R
- Subjects
Disease Models, Animal ,Mice ,Virulence ,Coxiella burnetii ,Acute Disease ,Chronic Disease ,Guinea Pigs ,Host-Pathogen Interactions ,Animals ,Mouse Models ,Q Fever ,Interleukin-10 - Abstract
Q fever, caused by the pathogen Coxiella burnetii, is an acute disease that can progress to become a serious chronic illness. The organism leads an obligate, intracellular lifecycle, during which it multiplies in the phagolytic compartments of the phagocytic cells of the immune system of its hosts. This characteristic makes study of the organism particularly difficult and is perhaps one of the reasons why, more than 70 y after its discovery, much remains unknown about the organism and its pathogenesis. A variety of animal species have been used to study both the acute and chronic forms of the disease. Although none of the models perfectly mimics the disease process in humans, each opens a window onto an important aspect of the pathology of the disease. We have learned that immunosuppression, overexpression of IL10, or physical damage to the heart muscle in mice and guinea pigs can induce disease that is similar to the chronic disease seen in humans, suggesting that this aspect of disease may eventually be fully understood. Models using species from mice to nonhuman primates have been used to evaluate and characterize vaccines to protect against the disease and may ultimately yield safer, less expensive vaccines.
- Published
- 2013
47. Antiviral Screening of Multiple Compounds against Ebola Virus
- Author
-
Dowall, Stuart, primary, Bewley, Kevin, additional, Watson, Robert, additional, Vasan, Seshadri, additional, Ghosh, Chandradhish, additional, Konai, Mohini, additional, Gausdal, Gro, additional, Lorens, James, additional, Long, Jason, additional, Barclay, Wendy, additional, Garcia-Dorival, Isabel, additional, Hiscox, Julian, additional, Bosworth, Andrew, additional, Taylor, Irene, additional, Easterbrook, Linda, additional, Pitman, James, additional, Summers, Sian, additional, Chan-Pensley, Jenny, additional, Funnell, Simon, additional, Vipond, Julia, additional, Charlton, Sue, additional, Haldar, Jayanta, additional, Hewson, Roger, additional, and Carroll, Miles, additional
- Published
- 2016
- Full Text
- View/download PDF
48. Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model
- Author
-
Dowall, Stuart D., primary, Bosworth, Andrew, additional, Watson, Robert, additional, Bewley, Kevin, additional, Taylor, Irene, additional, Rayner, Emma, additional, Hunter, Laura, additional, Pearson, Geoff, additional, Easterbrook, Linda, additional, Pitman, James, additional, Hewson, Roger, additional, and Carroll, Miles W., additional
- Published
- 2015
- Full Text
- View/download PDF
49. Dengue virus serotype 3, Karachi, Pakistan
- Author
-
Jamil, Bushra, Hasan, Rumina, Zafar, Afia, Bewley, Kevin, Chamberlain, John, Mioulet, Valerie, Rowlands, Moira, and Hewson, Roger
- Abstract
To the Editor: The global prevalence of dengue fever (DF) has grown dramatically in recent decades; DF is now endemic to >100 countries (1). Dengue hemorrhagic fever (DHF), a potentially [...]
- Published
- 2007
50. Assessment of the Protective Effect of Imvamune and Acam2000 Vaccines against Aerosolized Monkeypox Virus in Cynomolgus Macaques
- Author
-
Hatch, Graham J., primary, Graham, Victoria A., additional, Bewley, Kevin R., additional, Tree, Julia A., additional, Dennis, Mike, additional, Taylor, Irene, additional, Funnell, Simon G. P., additional, Bate, Simon R., additional, Steeds, Kimberley, additional, Tipton, Thomas, additional, Bean, Thomas, additional, Hudson, Laura, additional, Atkinson, Deborah J., additional, McLuckie, Gemma, additional, Charlwood, Melanie, additional, Roberts, Allen D. G., additional, and Vipond, Julia, additional
- Published
- 2013
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.