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6. Budget‐Friendly Generation, Biochemical Analyses, and Lentiviral Transduction of Patient‐Derived Colon Organoids

Author

Rigaux, Emilie, primary, Chen, Jia‐Wei, additional, George, Fabienne, additional, Lemaire, Julien, additional, Bertrand, Claude, additional, Faugeras, Laurence, additional, Fattaccioli, Antoine, additional, Gilliaux, Quentin, additional, D'Hondt, Lionel, additional, Michiels, Carine, additional, Renard, Henri‐François, additional, and Zanin, Natacha, additional

Published
2023
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10. Diagnosis and treatment in chronic pancreatitis: an international survey and case vignette study

Author

Moody, Frank G., Bertrand, Claude, Johnson, Colin, van Lander, Aude, Carter, Ross, Conneely, John B., Berrevoet, Frederik, Sousa Silva, Donzília, Li, Zong-Fang, Lévy, Philippe, Oppong, Kofi, Gardner, Timothy B., Wilcox, C. Mel, French, Jeremy, Steer, Michael, Bradley, Edward L., III, Layer, Peter, Napoleon, Bertrand, Mosquera, Jorge Antonio, Gouma, D.J., Andersson, Roland, Manzelli, Antonio, Klaase, J.M., Falconi, Massimo, de-Madaria, Enrique, Casadei, Riccardo, Malleo, Giuseppe, Pezzilli, Raffaele, Malecka-Panas, Ewa, Lohr, Matthias, Mayerle, Julia, Rauws, Erik A.J., Freeman, Martin L., Ariffin, Affirul Chairil, Vasavada, Bhavin, Lai, Paul Bo-San, Beristain-Hernandez, Jose Luis, Juan, Álvarez, Plaudis, Haralds, Vrochides, Dionisios, Neri, Vincenzo, Velayutham, Vimalraj, Andrianov, Aleksey, Figueras, Joan, Soreide, Kjetil, Shcherba, Aliaksei, Gachabayov, Mahir, Keith, Roger G., Tsoulfas, Georgios, Fink, Michael Anthony, Crippa, Stefano, Nikfarjam, Mehrdad, Bora, Dibyajyoti, Desai, Rajendra, Donati, Marcello, Bong, Jan Jin, Martínez Moneo, Emma, Morris-Stiff, Gareth, Coker, Ahmet, de Resende, Alexandre Prado, Bhalerao, Suryabhan Sakhahari, Sikora, Sadiq S., Kelemen, Dezső, Czakó, László, Ramesh, Hariharan, Rummo, Oleg, Fedaruk, Aliaksei, Hlinnik, Alexey, Chinthakindi, Madhusudhan, Dumitrascu, Traian, Egorov, Vyacheslav, Bettschart, Vincent, Molinari, Michele, Guillermo, E. Aldana D., Orloff, Susan L., Kostov, Daniel Vasilev, Sulpice, Laurent, Knowles, Brett, Kimura, Yasutoshi, Marangoni, Gabriele, Joshi, Rajeev, Gyökeres, Tibor, Bedin, Vladimir, V., Ivanecz, Arpad, Antonucci, Adelmo, Omoshoro-Jones, Jones A.O., Nakache, Richard, Del Chiaro, Marco, Johnstone, Marianne, Saito, Tomoaki, Balzano, Gianpaolo, Chooklin, Serge, Boraschi, Piero, Park, Walter, Pereira, Pedro Nuno Valente Reis, Pagano, Nico, Lykoudis, Pavlos, Partecke, Lars Ivo, Siatkouski, Aliaksandr, Martín, Rosa Jorba, Kawabata, Yasunari, Lourenço, Luís Carvalho, Marra-Lopez, Carlos, Lee, Jun Kyu, Habbe, Nils, Verdonk, Robert C., Rabotyagova, Yliya, Talukdar, Rupjyoti, Frulloni, Luca, Galeev, Shamil, Berger, Zoltán, Yasuda, Takeo, Hackert, Thilo, Saatov, Ziyovuddin, Raptis, Dimitri Aristotle, Boadas, Jaume, Vitali, Francesco, Archibugi, Livia, Ryska, Miroslav, Tihanyi, Balazs, Singh, Vikesh K., Masamune, Atsushi, Yeaton, Paul, Smith, Kerrington D., Modi, Shrey, Cosen-Binker, Laura, Barreto, Savio George, Morandi, Eugenio, Valeri, Sergio, Morioka, Cintia Yoko, Lara, Luis F., Takeyama, Yoshifumi, Gress, Frank G., Yu, Young-Dong, Gaia, Ezio, Barbu, Sorin Traian, İnce, Ali Tüzün, Deeprasertvit, Akkraporn, Chang, Yu-Ting, Abiola, Stephen Olusola, Kacar, Sabite, Muscarella, Peter, II, Braat, Henri, Han, Samuel, Aghdassi, Ali A., Frossard, Jean-Louis, Smith, Jill P., Schwartz, M.P., van Dullemen, H.M., Venneman, N.G., Spanier, B.W.M., Kuiken, Sjoerd, van Geenen, Erwin, Beilman, Greg, Papachristou, Georgios, Chapa Azuela, Oscar, van der Schaar, P., Oruc, Nevin, Anten, Marie-Paule, Nealon, William H., García-Cano, Jesús, Jovani, Manol, Melki, Ziad, Ibrahim, Mustafa Mohammed Ahmed, Awajdarip, M.U., Azam, Mohammad, Sabu, K.G., Ermolaev, Igor, Shetty, Shiran, Oana, Belei, Pokrotnieks, Juris, Lazuchiewicz-Kot, Malgorzata, Bouali, Riadh, Winiarski, Marek, Schmitt, Marcus, Rimbas, Mihai, Meining, Alexander, Erwan, Bories, Meier, Peter N., Schoefl, Rainer, Altonbary, Ahmed Youssef, Marsteller, Igor, Wallstabe, Ingo, Prifti, Skerdi, Lemmers, Arnaud, Horvath, M., Kumar, Ajay, Palermo, Joseph J., Issa, Yama, van Santvoort, Hjalmar C., Fockens, Paul, Besselink, Marc G., Bollen, Thomas L., Bruno, Marco J., and Boermeester, Marja A.

Published
2017
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17. Self-Expanding Covered Metallic Stent as a Bridge to Surgery in Esophageal Cancer: Impact on Oncologic Outcomes

Author

Dhahri, Abdennahceur, Lignier, Delphine, Cossé, Cyril, Regimbeau, Jean-Marc, Luc, Guillaume, Cabau, Magalie, Jougon, Jacques, Lozach, Patrick, Thereaux, Jérémie, Badic, Bogdan, Cappeliez, Serge, El Nakadi, Issam, Lebreton, Gil, Alves, Arnaud, Flamein, Renaud, Pezet, Denis, Pipitone, Federica, Stan-Iuga, Bogdan, Contival, Nicolas, Pappalardo, Eric, Msika, Simon, Mantziari, Styliani, Hec, Flora, Vanderbeken, Marguerite, Tessier, Williams, Briez, Nicolas, Fredon, Fabien, Gainant, Alain, Mathonnet, Muriel, Mezoughi, Salim, Ducerf, Christian, Baulieux, Jacques, Bigourdan, Jean-Marc, Pasquer, Arnaud, Baraket, Oussama, Poncet, Gilles, Adam, Mustapha, Vaudoyer, Delphine, Jourdan Enfer, Peggy, Villeneuve, Laurent, Glehen, Olivier, Coste, Thibault, Fabre, Jean-Michel, Marchal, Frédéric, Frisoni, Romain, Ayav, Ahmet, Brunaud, Laurent, Bresler, Laurent, Cohen, Charlotte, Aze, Olivier, Venissac, Nicolas, Pop, Daniel, Mouroux, Jérôme, Donici, Ion, Prudhomme, Michel, Felli, Emanuele, Lisunfui, Stéphanie, Seman, Marie, Godiris Petit, Gaelle, Karoui, Mehdi, Tresallet, Christophe, Ménégaux, Fabrice, Vaillant, Jean-Christophe, Hannoun, Laurent, Malgras, Brice, Lantuas, Denis, Pautrat, Karine, Pocard, Marc, Valleur, Patrice, Chafai, Najim, Balladur, Pierre, Lefrançois, Magalie, Parc, Yann, Paye, François, Tiret, Emmanuel, Nedelcu, Marius, Laface, Letizia, Perniceni, Thierry, Gayet, Brice, Turner, Kathleen, Filipello, Alexandre, Porcheron, Jack, Tiffet, Olivier, Kamlet, Noémie, Chemaly, Rodrigue, Klipfel, Amandine, Pessaux, Patrick, Brigand, Cecile, Rohr, Serge, du Rieu, Mael Chalret, Da Re, Chiara, Dumont, Frédéric, Goéré, Diane, Elias, Dominique, Bertrand, Claude, Mariette, Christophe, Gronnier, Caroline, Duhamel, Alain, Mabrut, Jean-Yves, Bail, Jean-Pierre, Carrere, Nicolas, Lefevre, Jérémie H., Meunier, Bernard, Collet, Denis, and Piessen, Guillaume

Published
2015
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18. Get Better Data to Drive Production Gains in Tight Gas Reservoir Through an Automated Multiphase Measurement Skid and Production Engineering Workflow Integration

Author

Bertrand Claude Theuveny, Carlos Garay Andrade, Julio Sanz Vera, Fabian Salas, Claudio Pucci, and Alejandro Castro

Abstract

A novel implementation of an economical, self-sustainable and environmentally friendly solution for tight gas field production monitoring in a remote location in Tierra Del Fuego, allows early-stage production measurements necessary in the unconventional reservoir analysis for the field recovery process optimization The paper demonstrates the gains obtained with the deployment in 12 pads of an automated well testing multiphase metering skids for enhancing the efficiency of production engineering workflows. The replacement of traditional test separator and test manifold with a fully automated multiport selector valve manifold and a multiphase flowmeter enables a number of new production monitoring and surveillance workflows that can lead to additional production, while lowering both the capital expenditure and the operational costs. The enhanced data coverage and data quality provides reliable input to advanced engineering processes. The high level of repeatability provided by the multiphase flowmeter establishes a strong foundation for systematic, automatable workflows. We demonstrate the robustness of the data quality over time with the introduction of new indicators that can be automatically computed and deliver input to more evolved information algorithms. Beyond the reduction of capital expenditure of 11% and gains over 1100 man-hours per year per installed pads, we enable a number of production insights that translate in better reservoir management and production practices. High quality rate transient analysis can be performed leading to reliable outputs that leads to actionable decisions. Only few papers demonstrate actual multiphase flowmeter performance in tight gas fields and details how reliable production data is used on a daily basis to enhance reservoir management practices and leads to production optimization. The definition of new quality indicators on the data streams enables the feed to advanced algorithms and leads to enhanced automation of field management processes. Finally, we document and estimate the significant reduction on emissions enabled by the deployment of the multiport selector valve manifold and multiphase flowmeter.

Published
2022

29. Commentary: The Media in 2045--Not a Forecast, but a Dream.

Author

Bertrand, Claude-Jean

Abstract

Identifies a dozen major improvements to the mass media, relative either to the selection of information or to the presentation of it. Looks to the year 2045 when, without state intervention, the media may have developed a control system, based perhaps in universities, to monitor, evaluate, and advise the media. (TB)

Published
1995

31. Presacral Myelolipoma : The Usefulness of a 99mTc–Albumin Nanocolloid Scintigraphy

Author

UCL - SSS/IRSS - Institut de recherche santé et société, UCL - (MGD) Service de médecine nucléaire, UCL - (MGD) Service de chirurgie, UCL - (MGD) Service de radiologie - résonance magnétique, UCL - SSS/IREC/MONT - Pôle Mont Godinne, Guillaume, Laurent, Vander Borght, Thierry, Bertrand, Claude, Dupont, Michaël, Krug, Bruno, UCL - SSS/IRSS - Institut de recherche santé et société, UCL - (MGD) Service de médecine nucléaire, UCL - (MGD) Service de chirurgie, UCL - (MGD) Service de radiologie - résonance magnétique, UCL - SSS/IREC/MONT - Pôle Mont Godinne, Guillaume, Laurent, Vander Borght, Thierry, Bertrand, Claude, Dupont, Michaël, and Krug, Bruno

Abstract

Myelolipoma is a rare mesenchymal tumor consisting of adipose tissue and hematopoietic cells. Found usually in the adrenal region, however, few cases have been reported in extra-adrenal regions, most frequently in the presacral region. It is important to recognize such tumor, as it can attain massive size and causes pressure symptoms, and needs to be differentiated from malignant tumors, including liposarcomas. Although CT and MRI can suggest a diagnosis of myelolipoma, these are not conclusive. The hematopoietic cells are enhanced by a Tc-albumin nanocolloid scintigraphy and help to distinguish myolipoma from other entities.

Published
2021

32. Occurrence of sporadic medullary thyroid carcinoma in Graves' disease in association with a RET proto-oncogene mutation.

Author

UCL - (MGD) Service d'endocrinologie, UCL - (MGD) Service d'anatomie pathologique, UCL - (MGD) Service de chirurgie, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - SSS/IREC/MONT - Pôle Mont Godinne, Donckier, Julian, Fervaille, Caroline, Bertrand, Claude, UCL - (MGD) Service d'endocrinologie, UCL - (MGD) Service d'anatomie pathologique, UCL - (MGD) Service de chirurgie, UCL - SSS/IREC/EDIN - Pôle d'endocrinologie, diabète et nutrition, UCL - SSS/IREC/MONT - Pôle Mont Godinne, Donckier, Julian, Fervaille, Caroline, and Bertrand, Claude

Abstract

Graves' disease may be associated with thyroid cancer, particularly differentiated thyroid cancer. Medullary thyroid cancer (MTC) is less common. The occurrence of sporadic MTC in Graves' disease in the presence of a RET proto-oncogene has never been reported.: A 63-year-old woman was referred for Graves' disease. A thyroid ultrasound disclosed five nodules, one of which was classified as Eu-Tirads 5 with a size of 6.7 × 6.5× 11 mm. Fine needle aspiration was reported as Bethesda class IV follicular neoplasm of a Hürthle cell subtype. Calcitonin level was found to be elevated. A total thyroidectomy confirmed the diagnosis of MTC and a bilateral cervical lymphadenectomy was performed, with four lymph nodes being infiltrated by MTC. Genetic testing revealed a M918T mutation in the RET proto-oncogene.: MTC may occur in Graves' disease, especially if a nodule is present. In this case, genetic testing should always be performed even if MTC is sporadic. Increased incidence of thyroid cancer in autoimmune thyroid diseases, as well as the link existing between autoimmunity, inflammation and carcinogenesis, leads us to hypothesize that the association here reported is not coincidental.

Published
2021

33. Hypoxia-induced Angiogenesis Rescues Survival from Small for Size Syndrome (SFSS)

Author

UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Dili, Alexandra, De Rudder, M., Pirlot, B., Bertrand, Claude, Dewachter, L., Bouzin, C., Leclercq, I., UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de cardiologie, Dili, Alexandra, De Rudder, M., Pirlot, B., Bertrand, Claude, Dewachter, L., Bouzin, C., and Leclercq, I.

Abstract

After extended hepatectomy, hepatocyte proliferation proceeds sinusoidal endothelial cell (SEC) remodeling causing a transient perturbation of the lobular architecture with proliferating hepatocytes forming avascular, hypoxic, clusters. Hypoxia is, thus, considered at the origin of liver dysfunction in SFSS-hepatectomy. Recently, we showed that activation of hypoxia sensors in an upfront SFSS-hepatectomy surged an early angiogenic switch and preserved the sinusoidal architecture with a favorable impact on survival.

Published
2021

38. Clinical Outcomes After Total Pancreatectomy: A Prospective Multicenter Pan-European Snapshot Study

Author

Latenstein, Anouk E J, Scholten, Lianne, Al-Saffar, Hasan Ahmad, Björnsson, Bergthor, Butturini, Giovanni, Capretti, Giovanni, Chatzizacharias, Nikolaos A, Dervenis, Chris, Frigerio, Isabella, Gallagher, Tom K, Gasteiger, Silvia, Halimi, Asif, Labori, Knut J, Montagnini, Greta, Muñoz-Bellvis, Luis, Nappo, Gennaro, Nikov, Andrej, Pando, Elizabeth, de Pastena, Matteo, de la Peña-Moral, Jesús M, Radenkovic, Dejan, Roberts, Keith J, Salvia, Roberto, Sanchez-Bueno, Francisco, Scandavini, Chiara, Serradilla-Martin, Mario, Stättner, Stefan, Tomazic, Ales, Varga, Martin, Zavrtanik, Hana, Zerbi, Alessandro, Erkan, Mert, Kleeff, Jörg, Lesurtel, Mickaël, Besselink, Marc G, Ramia-Angel, Jose M, Scientific, Research Committee of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA), Bertrand, Claude, UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de chirurgie

Subjects
medicine.medical_specialty, Total pancreatectomy, Subgroup analysis, Logistic regression, Malignant disease, 03 medical and health sciences, 0302 clinical medicine, Pancreatectomy, Postoperative Complications, Blood loss, Pan european, Internal medicine, medicine, Humans, In patient, Major complication, Prospective Studies, Retrospective Studies, business.industry, Length of Stay, 3. Good health, Treatment Outcome, Elective Surgical Procedures, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Surgery, business
Abstract

OBJECTIVE To assess outcomes among patients undergoing total pancreatectomy (TP) including predictors for complications and in-hospital mortality. BACKGROUND Current studies on TP mostly originate from high-volume centers and span long time periods and therefore may not reflect daily practice. METHODS This prospective pan-European snapshot study included patients who underwent elective (primary or completion) TP in 43 centers in 16 European countries (June 2018-June 2019). Subgroup analysis included cut-off values for annual volume of pancreatoduodenectomies (

Published
2020

39. COVID-19 pandemic: implications on the surgical treatment of gastrointestinal and hepatopancreatobiliary tumours in Europe

Author

Nevermann, N F, Hillebrandt, K H, Knitter, S, Ritschl, P V, Krenzien, F, Benzing, C, Bahra, M, Biebl, M, Sauer, I M, Öllinger, R, Schöning, W, Schmelzle, M, Pratschke, J, Abu Hilal, Mohammad, Aldrighetti, Luca, Andersson, Roland, András, Vereczkei, Andreou, Andreas, Arer, İlker Murat, Atıcı, Ali Emre, Szijártó, Attila, Ayav, Ahmet, Aydın, Hüseyin Onur, Bartsch, Detlev, Belli, Andrea, Bertrand, Claude, Bockhorn, Maximilian, Bolli, Martin, Brekalo, Zdrinko, Bruns, Christiane, Ciria, Ruben, Coker, Ahmet, Croner, Roland, dHoore, Andre, Demartines, Nicolas, Demir, Ekin, Dibra, Arvin, Dilek, Osman Nuri, Dogrul, Ahmet, Efanov, Mikhail, Ekmekcigil, Ela, Ergün, Sefa, Farsi, Marco, Fichtner-Feigl, Stefan, Fretland, Åsmund, Friess, Helmut, Beets, Geerard, Gloor, Beat, Gockel, Ines, Gökakın, Ali Kağan, Gomez i Gavara, Concepción, Gretschel, Stephan, Hackl, Christina, Hecker, Andreas, Heinrich, Stefan, Huber, Tobias, Ibis, Cem, Izbicki, Jakob R, Kahlert, Christoph, Kamphues, Carsten, Kapan, Selin, Kazemier, Geert, Kleeff, Joerg, Klink, Christian, Knoefel, Wolfram, Kosieradzki, Maciej, Kube, Rainer, Löb, Stefan, Maagaard Andersen, Lars, Matthaei, Hanno, Mittler, Jens, Morgul, Mehmet Haluk, Moszkowicz, David, Musanovic, Nermin, Nickel, Felix, Nilsson, Magnus, Öfner, Dietmar, Oruğ, Taner, Pascher, Andreas, Pessaux, Patrick, Radionov, Michail, Raraty, Michael, Reissfelder, Christoph, Rhaiem, Rami, Rotellar, Fernando, Ryska, Miroslav, López-Ben, Santiago, Saribeyoglu, Kaya, Schafmayer, Clemens, Schmelzle, Moritz, Schmidt, Thomas, Schneider, Martin, Schoenberg, Markus, Schöning, Wenzel, Seehofer, Daniel, Sönmez, Recep Erçin, Soubrane, Olivier, Stange, Daniel, Strücker, Benjamin, Tursunovic, Amir, Tüzüner, Acar, Vondran, Florian, Weber, Georg, Wellner, Ulrich, Yazici, Pinar, Yeğen, Cumhur, Yol, Sinan, Institut de Recherche sur les Maladies Virales et Hépatiques (IVH), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), COVID‐19 Surgical Oncology Collaboration Group, Nevermann, N. F., Hillebrandt, K. H., Knitter, S., Ritschl, P. V., Krenzien, F., Benzing, C., Bahra, M., Biebl, M., Sauer, I. M., Ollinger, R., Schoning, W., Schmelzle, M., Pratschke, J., Abu Hilal, M., Aldrighetti, L., Andersson, R., Andras, V., Andreou, A., Arer, I. M., Atici, A. E., Szijarto, A., Ayav, A., Aydin, H. O., Bartsch, D., Belli, A., Bertrand, C., Bockhorn, M., Bolli, M., Brekalo, Z., Bruns, C., Ciria, R., Coker, A., Croner, R., D'Hoore, A., Demartines, N., Demir, E., Dibra, A., Dilek, O. N., Dogrul, A., Efanov, M., Ekmekcigil, E., Ergun, S., Farsi, M., Fichtner-Feigl, S., Fretland, A., Friess, H., Beets, G., Gloor, B., Gockel, I., Gokakin, A. K., Gomez i Gavara, C., Gretschel, S., Hackl, C., Hecker, A., Heinrich, S., Huber, T., Ibis, C., Izbicki, J. R., Kahlert, C., Kamphues, C., Kapan, S., Kazemier, G., Kleeff, J., Klink, C., Knoefel, W., Kosieradzki, M., Kube, R., Lob, S., Maagaard Andersen, L., Matthaei, H., Mittler, J., Morgul, M. H., Moszkowicz, D., Musanovic, N., Nickel, F., Nilsson, M., Ofner, D., Orug, T., Pascher, A., Pessaux, P., Radionov, M., Raraty, M., Reissfelder, C., Rhaiem, R., Rotellar, F., Ryska, M., Lopez-Ben, S., Saribeyoglu, K., Schafmayer, C., Schmidt, T., Schneider, M., Schoenberg, M., Seehofer, D., Sonmez, R. E., Soubrane, O., Stange, D., Strucker, B., Tursunovic, A., Tuzuner, A., Vondran, F., Weber, G., Wellner, U., Yazici, P., Yegen, C., Yol, S., UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service de chirurgie

Subjects
medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pneumonia, Viral, MEDLINE, Surveys and Questionnaires, Correspondence, Pandemic, Humans, Medicine, General, Surgical treatment, Intensive care medicine, Referral and Consultation, Pandemics, Gastrointestinal Neoplasms, SARS-CoV-2, business.industry, Liver Neoplasms, COVID-19, Liver Transplantation, Europe, Pancreatic Neoplasms, Biliary Tract Neoplasms, Surgical Oncology, Italy, Surgical Procedures, Operative, Surgery, Coronavirus Infections, business, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Published
2020
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40. Clinical Outcomes after Total Pancreatectomy: A Prospective Multicenter Pan-European Snapshot Study.

Author

UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de chirurgie, Latenstein, Anouk E J, Scholten, Lianne, Al-Saffar, Hasan Ahmad, Björnsson, Bergthor, Butturini, Giovanni, Capretti, Giovanni, Chatzizacharias, Nikolaos A, Dervenis, Chris, Frigerio, Isabella, Gallagher, Tom K, Gasteiger, Silvia, Halimi, Asif, Labori, Knut J, Montagnini, Greta, Muñoz-Bellvis, Luis, Nappo, Gennaro, Nikov, Andrej, Pando, Elizabeth, de Pastena, Matteo, de la Peña-Moral, Jesús M, Radenkovic, Dejan, Roberts, Keith J, Salvia, Roberto, Sanchez-Bueno, Francisco, Scandavini, Chiara, Serradilla-Martin, Mario, Stättner, Stefan, Tomazic, Ales, Varga, Martin, Zavrtanik, Hana, Zerbi, Alessandro, Erkan, Mert, Kleeff, Jörg, Lesurtel, Mickaël, Besselink, Marc G, Ramia-Angel, Jose M, Scientific, Research Committee of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA), Bertrand, Claude, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de chirurgie, Latenstein, Anouk E J, Scholten, Lianne, Al-Saffar, Hasan Ahmad, Björnsson, Bergthor, Butturini, Giovanni, Capretti, Giovanni, Chatzizacharias, Nikolaos A, Dervenis, Chris, Frigerio, Isabella, Gallagher, Tom K, Gasteiger, Silvia, Halimi, Asif, Labori, Knut J, Montagnini, Greta, Muñoz-Bellvis, Luis, Nappo, Gennaro, Nikov, Andrej, Pando, Elizabeth, de Pastena, Matteo, de la Peña-Moral, Jesús M, Radenkovic, Dejan, Roberts, Keith J, Salvia, Roberto, Sanchez-Bueno, Francisco, Scandavini, Chiara, Serradilla-Martin, Mario, Stättner, Stefan, Tomazic, Ales, Varga, Martin, Zavrtanik, Hana, Zerbi, Alessandro, Erkan, Mert, Kleeff, Jörg, Lesurtel, Mickaël, Besselink, Marc G, Ramia-Angel, Jose M, Scientific, Research Committee of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA), and Bertrand, Claude

Abstract

To assess outcomes among patients undergoing total pancreatectomy (TP) including predictors for complications and in-hospital mortality. Current studies on TP mostly originate from high-volume centers and span long time periods and therefore may not reflect daily practice. This prospective pan-European snapshot study included patients who underwent elective (primary or completion) TP in 43 centers in 16 European countries (June 2018-June 2019). Subgroup analysis included cut-off values for annual volume of pancreatoduodenectomies (<60 vs. ≥60). Predictors for major complications and in-hospital mortality were assessed in multivariable logistic regression. In total, 277 patients underwent TP, mostly for malignant disease (73%). Major postoperative complications occurred in 70 patients (25%). Median hospital stay was 12 days (IQR 9-18) and 40 patients were readmitted (15%). In-hospital mortality was 5% and 90-day mortality 8%. In the subgroup analysis, in-hospital mortality was lower in patients operated in centers with ≥60 pancreatoduodenectomies compared < 60 (4% vs. 10%, p = 0.046). In multivariable analysis, annual volume < 60 pancreatoduodenectomies (OR 3.78, 95%CI 1.18-12.16, p = 0.026), age (OR 1.07, 95%CI 1.01-1.14, p = 0.046), and estimated blood loss ≥2L (OR 11.89, 95%CI 2.64-53.61, p = 0.001) were associated with in-hospital mortality. ASA ≥3 (OR 2.87, 95%CI 1.56-5.26, p = 0.001) and estimated blood loss ≥2L (OR 3.52, 95%CI 1.25-9.90, p = 0.017) were associated with major complications. This pan-European prospective snapshot study found a 5% in-hospital after TP. The identified predictors for mortality, including low-volume centers, age, and increased blood loss, may be used to improve outcomes.

Published
2020

41. COVID-19 pandemic: implications on the surgical treatment of gastrointestinal and hepatopancreatobiliary tumours in Europe.

Author

UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de chirurgie, Nevermann, N F, Hillebrandt, K H, Knitter, S, Ritschl, P V, Krenzien, F, Benzing, C, Bahra, M, Biebl, M, Sauer, I M, Öllinger, R, Schöning, W, Schmelzle, M, Pratschke, J, COVID-19 Surgical Oncology Collaboration Group, Bertrand, Claude, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de chirurgie, Nevermann, N F, Hillebrandt, K H, Knitter, S, Ritschl, P V, Krenzien, F, Benzing, C, Bahra, M, Biebl, M, Sauer, I M, Öllinger, R, Schöning, W, Schmelzle, M, Pratschke, J, COVID-19 Surgical Oncology Collaboration Group, and Bertrand, Claude

Published
2020

43. Presacral Myelolipoma

Author

Guillaume, Laurent, primary, Vander Borght, Thierry, additional, Bertrand, Claude, additional, Dupont, Michael, additional, and Krug, Bruno, additional

Published
2021
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50. The journalism of the French Resistance

Author

Albert, Pierre and Bertrand, Claude-Jean

Subjects
World War II, 1939-1945, Journalism -- Influence, Mass communications
Abstract

The history of journalism during the period of the French Resistance, from 1940 to 1944, is presented. The freedom of the press was restricted and although some journalists joined the Resistance, the majority of writings came from other sources.

Published
2000

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