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1. Equine grass sickness in italy: a case series study

Author

Laus Fulvio, Corsalini Jacopo, Mandara Maria Teresa, Bazzano Marilena, Bertoletti Alice, and Gialletti Rodolfo

Subjects
Grass sickness, Equine Dysautonomia, horse, intestinal dysmotility, pasture, Veterinary medicine, SF600-1100
Abstract

Abstract Background Equine grass sickness (EGS) has been reported in several European and extra-European countries. Despite this, no scientific paper about clinical cases of EGS in Italy has been published. EGS is a disease affecting almost exclusively horses kept on pasture, characterized by clinical signs related to lesions in autonomic nervous system (ANS), particularly in the enteric nervous system (ENS). According to clinical presentation, acute, subacute and chornic syndromes can be observed, with various sympthoms including dullness, anorexia, dysphagia, drooling of saliva, tachycardia, ptosis, patchy sweating and muscle fasciculations. In horses affected by acute forms, mild to moderate abdominal pain and large volumes of nasogastric reflux can be observed. The etiology is still speculative and many hypothesis have been proposed to explain the pathogenesis. Case presentation The present study describes four cases of EGS (one subacute and three chronic forms) occurred in Central Italy during early spring. In all the cases included in the study, the prognosis was poor and the horses were euthanized. The diagnosis was confirmed by histological examination of ANS or ENS. In two cases, in vivo diagnosis was obtained by histological examination of enteric bioptic samples collected during laparoscopy. Conclusions EGS in Italy could be underdiagnosed and incidence understimated. Greater awareness should be applied in Italy for the inclusion of EGS in differential diagnosis for horses presenting clinical signs of abdominal pain associated or not with gastric reflux and muscular fasciculation. All the cases in this study concerned horses kept in the same pasture, confirming a possible premise-linked and management-linked factors on the ethiopathogenesis of EGS. The age of horses ranged from 2 to 6 years, that is consistent with the risk factor age for EGS (from 2 to 7 years of age). Previous suspected EGS diagnosis in the same livestock and recent cool dry weather were considered additional potential risk factors.

Published
2021
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5. Aura and osmophobia are associated with the IL1A -889C > T (rs1800587) variant in migraine

Author

Amanda Brant Rocha, Giovana Ortiz Zendrini, Maria Paula Bertoletti Juliani, Regina Célia Poli Frederico, Valéria Aparecida Bello, Carlos Eduardo Coral de Oliveira, Edna Maria Vissoci Reiche, and Aline Vitali-Silva

Subjects
Headache, Migraine Disorders, Interleukin-1alpha, Genetic Variation, Cefaleia, Transtornos de Enxaqueca, Interleucina-1alfa, Variação Genética, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Background Migraine belongs to the group of primary headaches, affecting 14.4% of the global population. The pathophysiological mechanisms of migraine involve the interplay between hypothalamic activation, cortical spreading depression, trigeminal stimulation, and inflammatory components with neurogenic inflammation or neuroinflammation.

Published
2024
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6. Agile Manifesto of Non-Formal Education for Older Adults -- A Co-Design Experience

Author

Lis Ângela De Bortoli, Ana Carolina Bertoletti De Marchi, Ana Sara Castaman, Barbara Barbosa Neves, Helenice de Moura Scortegagna, and Lenir Antonio Hannecker

Abstract

In educational gerontology, non-formal education emerges as a possibility for lifelong learning because it is more flexible and less bureaucratic than formal education. In this context, agile culture offers a potential strategy to enhance non-formal education. While there are four manifestos for agile culture in education, their application in later life is lacking in the literature. The objective is to discuss the agile culture in education and present the concept of the agile manifesto for non-formal education in later life. A co-design process was conducted to develop this manifesto, in which specialists in education, educational gerontology and agile culture, as well as an older person, participated in an active and collaborative way. The manifesto, which has four values and 18 principles, will serve as a guide for educators who intend to develop educational activities based on agile culture, for older adults, in the non-formal instance. It is proposed that the agile culture of non-formal education for older adults is fundamentally about collaboration, democracy, independence and autonomy, considering the needs of everyday life, as well as the multidimensionality and heterogeneity of those involved.

Published
2024
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7. Monitoring Educational Choices in Europe: An analysis of EU-SILC data. Exploring EU-SILC Data to Monitor Educational Systems in EU

Author

European Commission (Belgium), Joint Research Centre (JRC), Daniele Checchi, and Alice Bertoletti

Abstract

The European Education Area aims to support Member States' efforts in enhancing the educational attainment of younger generations. In this policy context, there is a need for an objective tool to assess the educational outcomes of EU countries. The present report addresses this need by pursuing two objectives: (1) providing a comprehensive method for using EU-SILC data to build relevant indicators for monitoring educational systems; (2) investigating the factors that explain variations in educational indicators across EU countries, with a particular focus on the influence of family inputs and personal characteristics. The empirical analysis is conducted using EU-SILC data from the 27 EU countries, employing various methodologies, including cluster analysis, principal component analysis, and correlational analysis. The results of this report demonstrate the potential of EU-SILC data in assessing educational systems in Europe. Furthermore, the findings offer valuable insights in support of the European Commission's objective of establishing a European Educational Area. The results also raise concerns, suggesting that education in Europe may not act as a universal equaliser. Instead, educational systems continue to exhibit social selectivity in influencing individuals' prospects for future careers.

Published
2024
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8. Assessment of bleeding events in patients receiving DOACs with or without statins to treat venous thromboembolism: insights from the RIETE registry

Author

Dominique Farge-bancel, R Marqués, M Ortiz, Paolo Prandoni, J Roa, Manuel Monreal, F Couturaud, J Gutierrez, J Pagan, Peter Verhamme, A Aujayeb, Laurent Bertoletti, P Verhamme, M Monreal, S Fonseca, S Pinto, S Soler, A Lorenzo, R Lecumberri, R Otero, P DI MICCO, F Rivera-Cívico, A Molino, P Suchon, C Grange, JA Caprini, J Osorio, Henri Bounameaux, R Valle, F Negro, A Tufano, Remedios Otero, Aitor Ballaz, G Kenet, I Francisco, F Uresandi, G Barillari, Marijan Bosevski, F García-Bragado, E Grau, D Jiménez, A Maestre, A Visonà, J Criado, R Chopard, I Weinberg, M Lumbierres, B Leclercq, H Bounameaux, Farid Rashidi, Abílio Reis, Lucia Mazzolai, P Llamas, MJ Núñez-Fernández, F Dentali, O Espitia, C Siniscalchi, Rosaria Del Giorno, Sanjiv Keller, Carmine Siniscalchi, Luciano Lopez-Jimenez, Ana Cristina Montenegro, Benjamin Brenner, Raquel Barb, Pierpaolo Di Micco, Sebastian Schellong, Inna Tzoran, Radovan Malý, Joseph A. Caprini, Hanh My Bui, MD Adarraga, A Alberich-Conesa, J Aibar, A Alda-Lozano, J Alfonso, C Amado, M Angelina-García, JI Arcelus, A Ballaz, R Barba, C Barbagelata, M Barrón, B Barrón-Andrés, F Beddar-Chaib, A Blanco-Molina, JC Caballero, J Carrillo-Alonso, G Castellanos, L Chasco, C De Ancos, J Del Toro, P Demelo-Rodríguez, C De Juana-Izquierdo, MC Díaz-Pedroche, JA Díaz-Peromingo, A Dubois-Silva, JC Escribano, C Falgá, AI Farfán-Sedano, C Fernández-Aracil, C Fernández-Capitán, B Fernández-Jiménez, JL Fernández-Reyes, MA Fidalgo, C Gabara, F Galeano-Valle, C García-González, A García-Ortega, O Gavín-Sebastián, MA Gil-De Gómez, A Gil-Díaz, C Gómez-Cuervo, A González-Munera, L Guirado, L Hernández-Blasco, L Jara-Palomares, MJ Jaras, I Jou, MD Joya, JL Lobo, L López-Jiménez, P López-Miguel, H López-Brull, JJ López-Núñez, A López-Ruiz, JB LópezSáez, O Madridano, PJ Marchena, M Marcos, M Martín del Pozo, F Martín-Martos, R Martínez-Prado, JM Maza, E Mena, MI Mercado, J Moisés, MV Morales, MS Navas, JA Nieto, M Olid, L Ordieres-Ortega, S Otálora, N Pacheco-Gómez, AC Palomeque, E Paredes, P Parra-Caballero, P Parra-Rosado, JM Pedrajas, C Pérez-Ductor, M Pérez-Pinar, MA Pérez-Jacoiste, ML Peris, ML Pesce, JA Porras, R Puchades, A Rodríguez-Cobo, M Romero-Brugera, P Ruiz-Artacho, N Ruiz-Giménez, J Ruiz-Ruiz, G Salgueiro, T Sancho, V Sendín, P Sigüenza, A Steinherr, S Suárez-Fernández, R Tirado, A TorrentsVilar, MI Torres, J Trujillo-Santos, JF Varona, A Villalobos, P Villares, C Ay, S Nopp, I Pabinger, C Van Edom, A Verstraete, Yoo HHB, AC Montenegro, SN Morales, J Hirmerova, R Malý, L Bertoletti, A BuraRiviere, J Catella, R Le Mao, I Mahé, F Moustafa, L Plaisance, G Sarlon-Bartoli, E Versini, S Schellong, B Brenner, I Tzoran, P Sadeghipour, F Rashidi, A Abenante, M Basaglia, M Bertoni, F Bilora, B Brandolin, M Ciammaichella, D Colaizzo, E Grandone, E Imbalzano, R Pesavento, A Poz, P Prandoni, B Taflaj, B Zalunardo, A Skride, D Kigitovica, J Meireles, M Bosevski, M Zdraveska, L Mazzolai, and HM Bui

Subjects
Medicine
Abstract

Objective To evaluate the impact of coadministering statins with direct oral anticoagulants (DOACs) on the risk of major bleeding events in patients with venous thromboembolism (VTE).Design Observational cohort analysis based on a multicentre international registry.Setting Data were extracted from the Registro Informatizado de Enfermedad TromboEmbolica Registry, which involves 205 centres across 27 countries.Participants A total of 73 659 patients diagnosed with VTE were classified based on their anticoagulant therapy (DOACs) versus low-molecular-weight heparin (LMWH) or vitamin K antagonists (VKAs) and concurrent use of statins.Methods Multivariable Cox proportional hazards models adjusted for confounding variables to assess the risk of major bleeding events stratified by the type of anticoagulant use and statin use.Results From October 2013 to February 2023, 73 659 patients were recruited: 2573 were statin users on DOACs, 14 090 were statin users on LMWH or VKA therapy, 10 088 were non-statin users on DOACs and 46 908 were non-statin users on LMWH or VKA therapy. Statin users were 10 years older and more likely to have hypertension, diabetes, renal failure or prior artery disease. During anticoagulation (median, 187 days), 1917 patients (2.6%) suffered major bleeding. Rates of major bleeding per 100 patient-years were 2.33 (95% CI 1.72 to 3.09), 3.75 (95% CI 3.43 to 4.10), 1.39 (95% CI 1.13 to 1.69) and 3.10 (95% CI 2.93 to 3.27), respectively. On multivariable analysis, patients treated with DOACs had a significantly lower risk of major bleeding compared with those on LMWH or VKA therapy (adjusted HR 0.59; 95% CI 0.48 to 0.74). The adjusted HR in statin users versus non-users was 1.03 (95% CI 0.92 to 1.14), while in statin users on DOACs versus the rest of patients, it was 1.18 (95% CI 0.79 to 1.76).Conclusions In patients with VTE receiving statins, long-term anticoagulation with DOACs was associated with a reduced risk of major bleeding, regardless of the statin use. These findings support the safety profile of DOACs over VKAs or LMWH in the management of VTE in patients requiring statins.

Published
2024
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14. Avoidant restrictive food intake disorder: recent advances in neurobiology and treatment

Author

Natasha K. O. Fonseca, Vitória D. Curtarelli, Juliana Bertoletti, Karla Azevedo, Tiago M. Cardinal, Júlia D. Moreira, and Luciana C. Antunes

Subjects
Avoidant restrictive food intake disorder, Eating disorders, Restrictive eating, Selective eating, Psychiatry, RC435-571
Abstract

Abstract Avoidant restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent insufficient nutritional and/or energy intake. ARFID, before referred to as “selective eating disorder”, was introduced recently in the DSM-5 as a replacement for and expansion of the previous diagnosis. Individuals with ARFID may limit food variety and intake due to avoidance based on the sensory characteristics of the food or related to any adverse consequences of eating without the intention of losing weight and concerns of body image. The limited understanding of avoidant and restrictive eating poses challenges to effective treatment and management, impacting directly on the growth and development of children and adolescents. The ARFID neurobiological concept has not yet been clearly defined to clinical practice for nutritionists, thereby hindering screening and impeding the development of treatment recommendations. This narrative review provide useful practical information to consult the pathophysiology, the neurobiology, the clinical features, the assessment and the treatment for healthcare professionals seeking to enhance their clinical knowledge and management of this disorder.

Published
2024
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16. Analysis of the zoonotic tick-borne encephalitis virus (TBEV) in raw milk and dairy products in mountain pastures of the Lombardy region, Italy

Author

Annalisa Scarazzato, Francesco Righi, Marco Pietro Sommariva, Irene Bertoletti, Giovanni Sala, Franco Paterlini, Paolo Daminelli, Guido Finazzi, Marina-Nadia Losio, and Enrico Pavoni

Subjects
tick-borne encephalitis, TBEV, raw milk, dairy, goat, cattle, Microbiology, QR1-502
Abstract

Over the last few decades, tick-borne encephalitis (TBE) has become a growing public health problem in Europe. The tick-borne encephalitis virus (TBEV) is a zoonotic virus that affects the central nervous system (CNS). TBEV has been detected in 27 European countries, and the rise in TBE cases is mainly due to environmental and ecological factors, and factors that increase the risk of human exposure to infected ticks. The infection via the alimentary route is the second most common means of TBEV transmission to humans. Raw milk from infected goats, sheep, or cows has been identified as a source of human food-borne infections. This study aims to gather new information on the prevalence of tick-borne encephalitis virus (TBEV) in raw goat’s and cow’s milk and related raw products in the Lombard Alps (Italy). This is important due to the close proximity of Lombardy to the Triveneto region, where TBE is endemic, and southern Switzerland, where numerous TBEV-positive mammals have been found. Throughout 2023, a passive monitoring plan was implemented on samples delivered for TBEV analyses from the Alpine pastures. In total, 248 specimens including raw milk, raw milk cheese, and butter were tested. This is the first monitoring of food at risk of TBEV transmission in a non-endemic region with evidence of TBEV circulation. Despite testing a wide range of dairy products, no sample tested positive for RNA-TBEV by real-time RT-PCR. Preliminary results suggest that raw milk and raw dairy products do not pose a significant risk of TBEV transmission to humans in the territory of Lombardy.

Published
2024
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17. Internet of Things and Machine Learning for Smart Healthcare

Author

da Costa, Cristiano André, Zeiser, Felipe André, da Rosa Righi, Rodrigo, Antunes, Rodolfo Stoffel, Alegretti, Ana Paula, Bertoni, Ana Paula, de Oliveira Ramos, Gabriel, de Mello, Blanda Helena, Vanin, Fausto, Bertoletti, Otávio Azevedo, Rigo, Sandro José, Kacprzyk, Janusz, Series Editor, Dorigo, Marco, Editorial Board Member, Engelbrecht, Andries, Editorial Board Member, Kreinovich, Vladik, Editorial Board Member, Morabito, Francesco Carlo, Editorial Board Member, Slowinski, Roman, Editorial Board Member, Wang, Yingxu, Editorial Board Member, Jin, Yaochu, Editorial Board Member, and Namasudra, Suyel, editor

Published
2024
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18. Tick-Borne Encephalitis, Lombardy, Italy

Author

Alessandra Gaffuri, Davide Sassera, Mattia Calzolari, Lucia Gibelli, Davide Lelli, Alessandra Tebaldi, Nadia Vicari, Alessandro Bianchi, Claudio Pigoli, Monica Cerioli, Luca Zandona, Giorgio Varisco, Irene Bertoletti, Paola Prati

Subjects
Tick-borne encephalitis -- Health aspects, Health
Abstract

Tick-borne encephalitis (TBE) is a considerable public health concern caused by the tick-borne encephalitis virus (TBEV), a member of the Flaviviridae family. This virus is classified into 5 genotypes; European, [...]

Published
2024
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19. Championing health systems management with digital innovation and applications in the age of artificial intelligence: protocol for a research program [version 1; peer review: awaiting peer review]

Author

Ericles Andrei Bellei and Ana Carolina Bertoletti De Marchi

Subjects
Study Protocol, Articles, Health Systems, Artificial Intelligence, Digital Health, Health Management, Innovation
Abstract

Health systems are experiencing increasing pressures worldwide due to heightened service demands, demographic aging, stringent regulations, and economic constraints, making efficiency and efficacy in health management critical aspects. At the heart of this complexity, health managers seek to optimize resources and improve care delivery at a time when the adoption of digital technologies, including artificial intelligence (AI), becomes increasingly imperative. This necessity reflects not only the pursuit of innovation but also the urgency to adapt to an ever-evolving environment. However, the effective characterization, availability, and incorporation of these technologies as support tools still represent an emerging challenge that is insufficiently explored in the literature. In response, this project proposes the development of a framework of theoretical and practical guidelines for the implementation and management of digital tools in health systems in the age of AI. Adopting a mixed-methods approach that includes systematic review, analyses of commercial off-the-shelf solutions, and qualitative studies with health managers and practitioners, the aim is to map current technology use, identify gaps and best practices, and provide a guide for future direction. This project also intends to develop in co-creation with professionals in the field to ensure the relevance and practical applicability of the developed guidelines. The results are expected to not only contribute to the scientific literature but also offer an evidence-based guide to optimizing the use of digital technologies in health management, promoting a significant transformation in the development and adoption of innovative digital solutions.

Published
2024
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20. A pilot study of a new app based on self-compassion for the prevention and promotion of mental health among Brazilian college students

Author

Bruno Luis Schaab, Lara Finkler Cunha, Desiree Cordoni Silveira, Pamela Carvalho da Silva, Kellen Greff Ballejos, Gabriela Bertoletti Diaz, Vanessa Kaiser, Prisla Ücker Calvetti, Sílvio César Cazella, Helena Maria Tannhauser Barros, and Caroline Tozzi Reppold

Subjects
positive psychology, self-compassion, app, students, mental health, intervention, Psychology, BF1-990
Abstract

IntroductionEpidemiological data suggest substantial issues on the mental health of university students worldwide. Self-compassion is associated with lower rates of psychological distress and better positive mental health. Thus, we have developed a app-based intervention based on self-compassion principles targeting the prevention and promotion of mental health in college students. The current pilot study assessed adherence to intervention, preliminary mental health benefits, and satisfaction and acceptability with the app among Brazilian college students.MethodsThe study employed a pre-experimental single-group design along with pre-test and post-test assessments (n = 23). A mixed methods approach was utilized to comprehensively assess the outcomes of the intervention.ResultsThe overall adherence rate for the intervention was 37.87%, with 26.26% of participants successfully completing all modules. Among the 21 outcomes assessed, 15 exhibited statistically significant results. Notably, there was a substantial increase in self-compassion, demonstrating a large effect size (d = 1.15), and a moderate effect size reduction in stress (d = 0.62) and anxiety (d = 0.52). All satisfaction indicators for the intervention received scores above 7. The intervention was well-received by participants who completed it, although a potential barrier identified was the volume of text within the app and the need to adopt a more playful and concise format for the intervention.DiscussionDespite a notable participant dropout, the adherence to intervention aligns with patterns observed in other online interventions conducted in real-world settings. The observed mental health benefits, high satisfaction levels, and positive acceptance underscore the rationale for pursuing a subsequent randomized clinical trial.

Published
2024
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21. Psico Bot: a robot for psychological assessment of children and adolescents

Author

Eduardo dos Santos de Lima, Silvana Alba Scortegagna, and Ana Carolina Bertoletti de Marchi

Subjects
Mental health, Information Technologies, mHealth, psychological assessment, Psychology, BF1-990
Abstract

Chatbots can use fast, and sometimes specialized interactions in different situations, making them an option in the choice of tools to collect information. In the psychological assessment of children and adolescents, they can act as complementary sources, and help to describe, qualify and measure psychological and behavioral characteristics, in its various forms of expression, in different contexts. This study aimed to present Psico Bot, a chatbot developed to assess symptoms of anxiety and depression in children and adolescents. Consisting of 20 questions that map physical and psychological symptoms of the selected constructs, it was developed through the natural language Dialogflow for use in the Google Assistant conversation platform. The design of Psico Bot is based on a neutral representation, with no determined gender or age, facilitating quick identification by the user. Based on the use of multimethod evaluations, the Psico Bot can offer relevant information about the mental health of children and adolescents using language and devices that are easy to understand and handle by this population. For the evaluator, the tool offers quick response and specific information about each construct, enabling more effective interventions in elements of greatest need.

Published
2024
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22. T cell hybrid immunity against SARS-CoV-2 in children: a longitudinal studyResearch in context

Author

Martin Qui, Smrithi Hariharaputran, Shou Kit Hang, Jinyan Zhang, Chee Wah Tan, Chia Yin Chong, Jenny Low, Linfa Wang, Antonio Bertoletti, Chee Fu Yung, and Nina Le Bert

Subjects
COVID-19, Immunology, Paediatrics, Vaccination, Adaptive immunity, T cell, Medicine, Medicine (General), R5-920
Abstract

Summary: Background: Hybrid immunity to SARS-CoV-2, resulting from both vaccination and natural infection, remains insufficiently understood in paediatric populations, despite increasing rates of breakthrough infections among vaccinated children. Methods: We conducted a prospective longitudinal study to investigate the magnitude, specificity, and cytokine profile of antigen-specific T cell responses elicited by breakthrough SARS-CoV-2 infection in a cohort of mRNA-vaccinated children (n = 29) aged 5–11. This longitudinal analysis involved six distinct time points spanning a 16-month period post-vaccination, during which we analysed a total of 159 blood samples. All children who were followed for at least 12 months (n = 26) experienced a breakthrough infection. We conducted cytokine release assays using minimal blood samples, and we verified the cellular origin of these responses through intracellular cytokine staining. Findings: After breakthrough infection, children who had received mRNA vaccines showed enhanced Th1 responses specific to Spike peptides. Additionally, their Spike-specific T cells exhibited a distinctive enrichment of CD4+ IFN-γ+IL10+ cells, a characteristic akin to adults with hybrid immunity. Importantly, vaccination did not impede the development of multi-specific T cell responses targeting Membrane, Nucleoprotein, and ORF3a/7/8 antigens. Interpretation: Children, previously primed with a Spike-based mRNA vaccine and experiencing either symptomatic or asymptomatic breakthrough infection, retained the ability to enhance and diversify Th1/IL-10 antigen-specific T cell responses against multiple SARS-CoV-2 proteins. These findings mirror characteristics associated with hybrid cellular immunity in adults, known to confer resistance against severe COVID-19. Funding: This study was funded by the National Medical Research Council (NMRC) Singapore (COVID19RF-0019, MOH-000019, MOH-000535, OFLCG19May-0034 and MOH-OFYIRG19nov-0002).

Published
2024
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23. Risk of recurrence after discontinuing anticoagulation in patients with COVID-19- associated venous thromboembolism: a prospective multicentre cohort studyResearch in context

Author

Luis Jara-Palomares, Behnood Bikdeli, David Jiménez, Alfonso Muriel, Pablo Demelo-Rodríguez, Farès Moustafa, Aurora Villalobos, Patricia López-Miguel, Luciano López-Jiménez, Sonia Otálora, María Luisa Peris, Cristina Amado, Romain Chopard, Francisco Rivera-Cívico, Manuel Monreal, María Dolores Adarraga, Ana Alberich Conesa, Jesús Aibar, Alicia Alda Lozano, Joaquín Alfonso, Jesús Alonso Carrillo, María Angelina García, Juan Ignacio Arcelus, Aitor Ballaz, Raquel Barba, María Barca Hernando, Cristina Barbagelata, Manuel Barrón, Belén Barrón Andrés, Fahd Beddar Chaib, María Ángeles Blanco Molina, Juan Carlos Caballero, Gonzalo Castellanos, Leyre Chasco, Juan Criado, Cristina de Ancos, Jorge del Toro, Pablo Demelo Rodríguez, Cristina de Juana Izquierdo, Ana María Díaz Brasero, José Antonio Díaz Peromingo, Álvaro Dubois Silva, Juan Carlos Escribano, Concepción Falgá, Ana Isabel Farfán Sedano, Cleofe Fernández Aracil, Carmen Fernández Capitán, Begoña Fernández Jiménez, José Luis Fernández Reyes, María Ángeles Fidalgo, Iria Francisco, Cristina Gabara, Francisco Galeano Valle, Francisco García Bragado, Alberto García Ortega, Olga Gavín Sebastián, María Allende Gil de Gómez, Aída Gil Díaz, Covadonga Gómez Cuervo, Adriana González Munera, Enric Grau, Leticia Guirado, Javier Gutiérrez, Luis Hernández Blasco, Luis Jara Palomares, María Jesús Jaras, Rafael Jiménez, Inés Jou, María Dolores Joya, Sara Lainez Justo, Antonio Lalueza, Ramón Lecumberri, José Manuel León Ramírez, Pilar Llamas, José Luis Lobo, Luciano López Jiménez, Patricia López Miguel, Juan José López Núñez, Antonio López Ruiz, Juan Bosco López Sáez, Alicia Lorenzo, Marina Lumbierres, Olga Madridano, Ana Maestre, Pablo Javier Marchena, María Marcos, Mar Martín del Pozo, Francisco Martín Martos, Jorge Manuel Maza, Elisabeth Mena, Maria Isabel Mercado, Jorge Moisés, María del Valle Morales, Maria Sierra Navas, José Antonio Nieto, Manuel Jesús Núñez Fernández, Mónica Olid, Lucía Ordieres Ortega, María Ortiz, Jeisson Osorio, Remedios Otero, Nazaret Pacheco Gómez, Javier Pagán, Andrea Catalina Palomeque, Ezequiel Paredes, Pedro Parra Caballero, José María Pedrajas, Cristina Pérez Ductor, Montserrat Pérez Pinar, María Lourdes Pesce, José Antonio Porras, Ramón Puchades, Francisco Rivera Cívico, Ana Rodríguez Cobo, Vladimir Rosa, Marta Romero Brugera, Pedro Ruiz Artacho, Nuria Ruiz Giménez, Justo Ruiz Ruiz, Georgina Salgueiro, Teresa Sancho, Vanesa Sendín, Patricia Sigüenza, Silvia Soler, Susana Suárez Fernández, Raimundo Tirado, Ana Torrents Vilar, María Isabel Torres, Javier Trujillo Santos, Fernando Uresandi, Reina Valle, José Felipe Varona, Paula Villares, Cihan Ay, Stephan Nopp, Ingrid Pabinger, Matthias Engelen, Thomas Vanassche, Peter Verhamme, Hugo Hyung Bok Yoo, Ana Cristina Montenegro, Silvia Natalia Morales, Jairo Roa, Jana Hirmerova, Radovan Malý, Laurent Bertoletti, Alessandra Bura-Riviere, Judith Catella, Francis Couturaud, Olivier Espitia, Claire Grange, Barbara Leclercq, Raphael Le Mao, Isabelle Mahé, Ludovic Plaisance, Gabrielle Sarlon Bartoli, Pierre Suchon, Edouard Versini, Sebastian Schellong, Benjamin Brenner, Najib Dally, Inna Tzoran, Parham Sadeghipour, Fahrid Rashidi, Alessia Abenante, Giovanni Barillari, Manuela Basaglia, Franca Bilora, Daniele Bissacco, Cristiano Bortoluzzi, Barbara Brandolin, Renato Casana, Maurizio Ciammaichella, Donatella Colaizzo, Francesco Dentali, Pierpaolo Di Micco, Elvira Grandone, Egidio Imbalzano, Daniela Lambertenghi Deliliers, Federica Negro, Raffaele Pesavento, Alessandra Poz, Paolo Prandoni, Paolo Scarinzi, Carmine Siniscalchi, Beldisa Taflaj, Antonella Tufano, Adriana Visonà, Ngoc Vo Hong, Beniamino Zalunardo, Andris Skride, Dana Kigitovica, Samuel Fonseca, Rafael Marques, José Meireles, Sara Barbosa Pinto, Marijan Bosevsky, Aleksandra Eftimova, Marijan Zdraveska, Henri Bounameaux, Lucia Mazzolai, Avinash Aujayeb, Joseph Caprini, Ido Weinberg, and Hanh My Bui

Subjects
Pulmonary embolism, Venous thromboembolism, Anticoagulation, COVID-19, SARS-CoV-2, Medicine (General), R5-920
Abstract

Summary: Background: The clinical relevance of recurrent venous thromboembolism (VTE) after discontinuing anticoagulation in patients with COVID-19-associated VTE remains uncertain. We estimated the incidence rates and mortality of VTE recurrences developing after discontinuing anticoagulation in patients with COVID-19-associated VTE. Methods: A prospective, multicenter, non-interventional study was conducted between March 25, 2020, and July 26, 2023, including patients who had discontinued anticoagulation after at least 3 months of therapy. All patients from the registry were analyzed during the study period to verify inclusion criteria. Patients with superficial vein thrombosis, those who did not receive at least 3 months of anticoagulant therapy, and those who were followed for less than 15 days after discontinuing anticoagulation were excluded. Outcomes were: 1) Incidence rates of symptomatic VTE recurrences, and 2) fatal PE. The rate of VTE recurrences was defined as the number of patients with recurrent VTE divided by the patient-years at risk of recurrent VTE during the period when anticoagulation was discontinued. Findings: Among 1106 patients with COVID-19-associated VTE (age 62.3 ± 14.4 years; 62.9% male) followed-up for 12.5 months (p25-75, 6.3–20.1) after discontinuing anticoagulation, there were 38 VTE recurrences (3.5%, 95% confidence interval [CI]: 2.5–4.7%), with a rate of 3.1 per 100 patient-years (95% CI: 2.2–4.2). No patient died of recurrent PE (0%, 95% CI: 0–7.6%). Subgroup analyses showed that patients with diagnosis in 2021–2022 (vs. 2020) (Hazard ratio [HR] 2.86; 95% CI 1.45–5.68) or those with isolated deep vein thrombosis (vs. pulmonary embolism) (HR 2.31; 95% CI 1.19–4.49) had significantly higher rates of VTE recurrences. Interpretation: In patients with COVID-19-associated VTE who discontinued anticoagulation after at least 3 months of treatment, the incidence rate of recurrent VTE and the case-fatality rate was low. Therefore, it conceivable that long-term anticoagulation may not be required for many patients with COVID-19-associated VTE, although further research is needed to confirm these findings. Funding: Sanofi and Rovi, Sanofi Spain.

Published
2024
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25. Evidence and unresolved questions in pulmonary hypertension: Insights from the 5th French Pulmonary Hypertension Network Meeting

Author

Boucly, Athénaïs, Bertoletti, Laurent, Fauvel, Charles, Dewavrin, Mélanie Gallant, Gerges, Christian, Grynblat, Julien, Guignabert, Christophe, Hascoet, Sébastien, Jaïs, Xavier, Jutant, Etienne-Marie, Lamblin, Nicolas, Meyrignac, Olivier, Riou, Marianne, Savale, Laurent, Tromeur, Cécile, Turquier, Ségolène, Valentin, Simon, Simonneau, Gérald, Humbert, Marc, Sitbon, Olivier, and Montani, David

Published
2024
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26. Venous thromboembolism characteristics and outcomes among RIETE patients tested and untested for inherited thrombophilia

Author

Adarraga, MD, Alberich-Conesa, A, Aibar, J, Alda-Lozano, A, Alfonso, J, Amado, C, Angelina-García, M, Arcelus, JI, Ballaz, A, Barba, R, Barbagelata, C, Barrón, M, Barrón-Andrés, B, Beddar-Chaib, F, Blanco-Molina, A, Caballero, JC, Castellanos, G, Criado, J, De Ancos, C, Del Toro, J, Demelo-Rodríguez, P, De Juana-Izquierdo, C, Díaz-Peromingo, JA, Dubois-Silva, A, Escribano, JC, Falgá, C, Farfán-Sedano, AI, Fernández-Aracil, C, Fernández-Capitán, C, Fernández-Jiménez, B, Fernández-Reyes, JL, Fidalgo, MA, Francisco, I, Gabara, C, Galeano-Valle, F, García-Bragado, F, García-Ortega, A, Gavín-Sebastián, O, Gil-Díaz, A, Gómez-Cuervo, C, González-García, C, González-Munera, A, Grau, E, Guirado, L, Gutiérrez-Guisado, J, Hernández-Blasco, L, Herreros, M, Jara-Palomares, L, Jaras, MJ, Jiménez, D, Jou, I, Joya, MD, Lecumberri, R, Llamas, P, Lobo, JL, López-Jiménez, L, López-Miguel, P, López-Brull, H, López-Núñez, JJ, López-Ruiz, A, López-Sáez, JB, Lorenzo, A, Lumbierres, M, Madridano, O, Maestre, A, Marchena, PJ, Marcos, M, Martín del Pozo, M, Martín-Martos, F, Martínez-Prado, R, Maza, JM, Mena, E, Mercado, MI, Moisés, J, Molino, A, Monreal, M, Morales, MV, Navas, MS, Nieto, JA, Núñez-Fernández, MJ, Olid, M, Ordieres-Ortega, L, Ortiz, M, Osorio, J, Otálora, S, Otero, R, Pacheco-Gómez, N, Pagán, J, Palomeque, AC, Paredes, E, Parra-Caballero, P, Pedrajas, JM, Pérez-Ductor, C, Pérez-Pinar, M, Peris, ML, Pesce, ML, Porras, JA, Puchades, R, Rivera-Cívico, F, Rodríguez-Cobo, A, Romero-Brugera, M, Ruiz-Artacho, P, Ruiz-Giménez, N, Ruiz-Ruiz, J, Salgueiro, G, Sancho, T, Sendín, V, Sigüenza, P, Soler, S, Steinherr, A, Suárez-Fernández, S, Tirado, R, Torrents-Vilar, A, Torres, MI, Trujillo-Santos, J, Uresandi, F, Valle, R, Varona, JF, Villalobos, A, Villares, P, Ay, C, Nopp, S, Pabinger, I, Vanassche, T, Verhamme, P, Verstraete, A, Yoo, HHB, Montenegro, AC, Morales, SN, Roa, J, Hirmerova, J, Malý, R, Bertoletti, L, Bura-Riviere, A, Catella, J, Chopard, R, Couturaud, F, Espitia, O, Grange, C, Le Mao, R, Leclercq, B, Mahé, I, Morange, P, Moustafa, F, Plaisance, L, Sarlon-Bartoli, G, Suchon, P, Versini, E, Schellong, S, Brenner, B, Dally, N, Kenet, G, Tzoran, I, Sadeghipour, P, Rashidi, F, Abenante, A, Barillari, G, Basaglia, M, Bertoni, M, Bilora, F, Brandolin, B, Ciammaichella, M, Colaizzo, D, Dentali, F, Di Micco, P, Grandone, E, Imbalzano, E, Negro, F, Pesavento, R, Poz, A, Prandoni, P, Siniscalchi, C, Taflaj, B, Tufano, A, Visonà, A, Zalunardo, B, Skride, A, Kigitovica, D, Zicans, M, Fonseca, S, Marques, R, Meireles, J, Pinto, S, Bosevski, M, Trajkova, M, Zdraveska, M, Bounameaux, H, Mazzolai, L, Aujayeb, A, Caprini, JA, Weinberg, I, Bui, HM, Cohen, Omri, Waldman Radinsky, Liat, Kenet, Gili, Mahé, Isabelle, Barillari, Giovanni, Soler, Silvia, Sigüenza, Patricia, Del Valle Morales, María, Villares, Paula, and Monreal, Manuel

Published
2024
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29. A prognostic score to identify women at increased risk for abnormal uterine bleeding during anticoagulation for venous thromboembolism

Author

Monreal, Manuel, Prandoni, Paolo, Brenner, Benjamin, Farge-Bancel, Dominique, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio, Bosevski, Marijan, Bounameaux, Henri, Malý, Radovan, Verhamme, Peter, Caprini, Joseph A., Bui, Hanh My, Adarraga, M.D., Agudo, P., Amado, C., Arcelus, J.I., Ballaz, A., Bascuñana, J., Barba, R., Barbagelata, C., Barrón, M., Barrón-Andrés, B., Blanco-Molina, A., Beddar Chaib, F., Botella, E., Cañas, I., Carrero-Arribas, R., Casado, I., Cerdá, P., Chasco, L., Criado, J., de Ancos, C., de Miguel, J., del Toro, J., Demelo-Rodríguez, P., Díaz-Brasero, A.M., Díaz-Pedroche, M.C., Díaz-Peromingo, J.A., Domínguez, I.M., Dubois-Silva, A., Escribano, J.C., Espósito, F., Farfán-Sedano, A.I., Falgá, C., Fernández-Capitán, C., Fernández-Jiménez, B., Fernández-Muixi, J., Fernández-Reyes, J.L., Font, C., Francisco, I., Galeano-Valle, F., García, M.A., García-Bragado, F., García de Herreros, M., Gavín-Blanco, O., Gil-Díaz, A., Gómez-Cuervo, C., Gómez-Mosquera, A.M., Gonzalez-Moreno, M., Grau, E., Guirado, L., Gutiérrez, J., Hernández-Blasco, L., Jara-Palomares, L., Jaras, M.J., Jiménez, D., Jou, I., Joya, M.D., Lacruz, B., Lainez-Justo, S., A, Latorre, J, Lima, Jl, Lobo, López-De la Fuente, M., López-Jiménez, L., López-Meseguer, M., López-Miguel, P., López-Núñez, J.J., López-Reyes, R., López-Sáez, J.B., Lorente, M.A., Lorenzo, A., Madridano, O., Maestre, A., Marchena, P.J., Martín-Guerra, J.M., Martín-Martos, F., Mellado, M., Mena, E., Moisés, J., Mercado, M.I., Monreal, M., Muñoz-Blanco, A., Muñoz-Gamito, G., Morales, M.V., Nieto, J.A., Noguera-Gras, E., Núñez-Fernández, M.J., Olid-Velilla, M., Osorio, J., Otalora, S., Otero, R., Paredes-Ruiz, D., Parra, P., Parra, V., Pedrajas, J.M., Pérez-López, M., Peris, M.L., Pesce, M.L., Porras, J.A., Poyo-Molina, J., Puchades, R., Riera-Mestre, A., Rivera-Civico, F., Rivera-Gallego, A., Roca, M., Rosa, V., Rodríguez-Cobo, A., Rodríguez-Matute, C., Ruiz-Artacho, P., Ruiz-Giménez, N., Ruiz-Ruiz, J., Salgueiro, G., Sancho, T., Sendín, V., Sigüenza, P., Soler, S., Suárez-Rodríguez, B., Suriñach, J.M., Tiberio, G., Torres, M.I., Torres-Sánchez, A., Trujillo-Santos, J., Uresandi, F., Usandizaga, E., Valle, R., Varona, J.F., Vela, L., Vela, J.R., Villalobos, A., Villares, P., Ay, C., Nopp, S., Pabinger, I., Engelen, M.M., Martens, C., Verhamme, P., Yoo, H.H.B., Arguello, J.D., Montenegro, A.C., Roa, J., Hirmerova, J., Malý, R., Accassat, S., Bertoletti, L., Bura-Riviere, A., Catella, J., Chopard, R., Couturaud, F., Espitia, O., El Harake, S., Le Mao, R., Mahé, I., Moustafa, F., Plaisance, L., Sarlon-Bartoli, G., Suchon, P., Versini, E., Schellong, S., Braester, A., Brenner, B., Kenet, G., Tzoran, I., Sadeghipour, P., Basaglia, M., Bilora, F., Bortoluzzi, C., Brandolin, B., Ciammaichella, M., De Angelis, A., Dentali, F., Di Micco, P., Imbalzano, E., Merla, S., Pesavento, R., Prandoni, P., Siniscalchi, C., Tufano, A., Visonà, A., Vo Hong, N., Zalunardo, B., Kigitovica, D., Rusa, E., Skride, A., Fonseca, S., Manuel, M., Meireles, J., Bosevski, M., Eftimova, A., Zdraveska, M., Bounameaux, H., Mazzolai, L., Aujayeb, A., Caprini, J.A., Weinberg, I., Bui, H.M., Sarlon-Bartoli, Gabrielle, Criado, Juan, Middeldorp, Saskia, Nieto, José Antonio, Díaz-Pedroche, María del Carmen, Moustafa, Farès, Ruiz-Giménez, Nuria, and DI Micco, Pierpaolo

Published
2023
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30. Investigating the effect of COVID-19 disruption in education using REDS data

Author

Alice Bertoletti and Zbigniew Karpiński

Subjects
Education (General), L7-991
Abstract

Abstract The Covid-19 pandemic has triggered a rapid and unprecedented transformation of global educational systems. The research community has uncovered important impacts of the pandemic on education worldwide, including detrimental effects on student learning, a decline in the well-being of teachers and students, and the exacerbation of educational disparities. Within this context, the Response to Education Disruption Survey (REDS) database stands out as one of the first large-scale international surveys specifically designed to examine the disruption caused by Covid-19 in education. This database serves as an initial step towards providing a more comprehensive understanding of the worldwide effects of the pandemic on education. The relevance of this database has inspired the creation of this special issue, collecting six studies that analyse the consequences of Covid-19 using REDS data.

Published
2024
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34. The Effect of the COVID-19 Disruption on the Gender Gap in Students' Performance: A Cross-Country Analysis

Author

Bertoletti, Alice, Biagi, Federico, Di Pietro, Giorgio, and Karpinski, Zbigniew

Abstract

Background: This paper investigates how the COVID-19 school closure has affected the gender gap in grade-8 students' performance and what are the drivers behind this. By analysing four different countries (i.e., the Russian Federation, Slovenia, Uzbekistan and the United Arab Emirates), the paper represents the first study addressing the issue from a comparative perspective. Methods: The study uses data from the Responses to Educational Disruption Survey (REDS) survey, which comprises international comparable data on how students approached remote learning during the COVID-19 disruption. The extent of the gender gap is estimated by employing an ordered logit model, while the Karlson-Holm-Breen (KHB) decomposition method is used to analyse the different potential channels that could account for the gender gap during COVID-19. Results: The empirical results reveal that, during the COVID-19 school closure, girls tended to perceive changes in their learnings less favourably than boys, both in terms of improvement in self-perceived learning and self-reported improvement in grades--with odds of a more affirmative response between 20 and 25% lower for girls relative to boys. The main drivers explaining this gender gap are physical activity and psychological distress of students during the COVID-19 disruption, as well as the perceived family climate. Conclusions: The paper shows systematic gender differences in how students perceived their educational outcomes changed due to the COVID-19 disruption, providing evidence on the factors driving these differences. The findings could be employed to design policy actions aimed at increasing gender equality in education.

Published
2023
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35. Venous thromboembolism characteristics, treatment and outcomes in young adults: findings from the Registro Informatizado de Enfermedad TromboEmbólica registry

Author

Monreal, Manuel, Prandoni, Paolo, Brenner, Benjamin, Farge-Bancel, Dominique, Barba, Raquel, Di Micco, Pierpaolo, Bertoletti, Laurent, Schellong, Sebastian, Tzoran, Inna, Reis, Abilio, Bosevski, Marijan, Bounameaux, Henri, Malý, Radovan, Verhamme, Peter, Caprini, Joseph A., Bui, Hanh My, Adarraga, M.D., Alberich-Conesa, A., Alonso-Carrillo, J., Amado, C., Amorós, S., Arcelus, J.I., Ballaz, A., Barba, R., Barbagelata, C., Barrón, M., Barrón-Andrés, B., Blanco-Molina, A., Botella, E., Casado, I., Chasco, L., Cerdà, P., Criado, J., del Toro, J., De Juana-Izquierdo, C., Demelo-Rodríguez, P., Díaz-Brasero, A.M., Díaz-Pedroche, M.C., Díaz-Peromingo, J.A., Dubois-Silva, A., Escribano, J.C., Espósito, F., Falgá, C., Fernández-Capitán, C., Fernández-Jiménez, B., Fernández-Muixi, J., Fernández-Reyes, J.L., Fidalgo, M.A., Font, C., Francisco, I., Galeano-Valle, F., García, M.A., García de Herreros, M., García-Bragado, F., García-Ortega, A., Gavín-Sebastián, O., Gil-Díaz, A., Gómez-Cuervo, C., Gómez-Mosquera, A.M., González-Martínez, J., González-Moreno, M., Grau, E., Guirado, L., Gutiérrez, J., Hernández-Blasco, L., Jaras, M.J., Jiménez, D., Jou, I., Joya, M.D., Lacruz, B., Lainez-Justo, S., Lalueza, A., Latorre, A., Lecumberri, R., Lobo, J.L., López-De la Fuente, M., López-Jiménez, L., López-Miguel, P., López-Núñez, J.J., López-Ruiz, A., López-Sáez, J.B., Lorenzo, A., Lumbierres, M., Madridano, O., Maestre, A., Marcos, M., Martín-Martos, F., Mellado, M., Mena, E., Mercado, M.I., Moisés, J., Monreal, M., Muñoz-Blanco, A., Muñoz-Gamito, G., Morales, M.V., Nieto, J.A., Noguera-Gras, E., Núñez-Fernández, M.J., Osorio, J., Otalora, S., Pacheco-Gómez, N., Paredes-Ruiz, D., Parra, P., Pedrajas, J.M., Pérez-Ductor, C., Pérez-Jacoiste, M.A., Pérez-Pérez, J.L., Peris, M.L., Porras, J.A., Poyo-Molina, J., Puchades, R., Riera-Mestre, A., Rivera-Civico, F., Rivera-Gallego, A., Roca, M., Rosa, V., Rodríguez-Cobo, A., Ruiz-Giménez, N., Salgueiro, G., Sancho, T., Sendín, V., Sigüenza, P., Soler, S., Suriñach, J.M., Tiberio, G., Torres, M.I., Trujillo-Santos, J., Uresandi, F., Usandizaga, E., Valle, R., Varona, J.F., Vela, L., Vela, J.R., Villalobos, A., Villares, P., Ay, C., Nopp, S., Pabinger, I., Engelen, M.M., Martens, C., Verhamme, P., Yoo, H.H.B., Arguello, J.D., Montenegro, A.C., Roa, J., Hirmerova, J., Malý, R., Accassat, S., Bertoletti, L., Bura-Riviere, A., Catella, J., Chopard, R., Couturaud, F., Espitia, O., Leclercq, B., Le Mao, R., Mahé, I., Moustafa, F., Plaisance, L., Poenou, G., Sarlon-Bartoli, G., Suchon, P., Versini, E., Schellong, S., Braester, A., Brenner, B., Kenet, G., Tzoran, I., Sadeghipour, P., Basaglia, M., Bilora, F., Bortoluzzi, C., Brandolin, B., Ciammaichella, M., Colaizzo, D., De Angelis, A., Dentali, F., Di Micco, P., Grandone, E., Imbalzano, E., Merla, S., Pesavento, R., Prandoni, P., Scarinzi, P., Siniscalchi, C., Tufano, A., Visonà, A., Vo Hong, N., Zalunardo, B., Gibietis, V., Kigitovica, D., Skride, A., Fonseca, S., Manuel, M., Meireles, J., Bosevski, M., Bounameaux, H., Mazzolai, L., Aujayeb, A., Caprini, J.A., Weinberg, I., Bui, H.M., Cohen, Omri, Barg, Assaf A., Nowak-Göttl, Ulrike, Amado-Fernández, Cristina, Mazzolai, Lucia, Tiberio, Gregorio, Skride, Andris, Morales, María del Valle, and Kenet, Gili

Published
2023
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36. Traduction et republication de : « Événements thromboemboliques artériels liés au cancer »

Author

Benhamou, Ygal, Benmaziane, Asmahane, Bertoletti, Laurent, Bichon, Virginie, Bozec, Coralie, Cohen, Ariel, Couturaud, Francis, Debourdeau, Philippe, Dielenseger, Pascale, Douriez, Éric, Élias, Antoine, Espitia, Olivier, Frère, Corinne, Gaboreau, Yoann, Gendron, Pascale, Girard, Philippe, Hanon, Olivier, Idbaih, Ahmed, Laporte, Silvy, Mahé, Isabelle, Mayeur, Didier, Mismetti, Patrick, Moustafa, Farès, Pernod, Gilles, Roy, Pierre-Marie, Rouge Bugat, Marie-Ève, Sanchez, Olivier, Schmidt, Jeannot, Scotté, Florian, and Sevestre, Maie-Antoinette

Published
2024
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37. Clinical outcomes after discontinuing anticoagulant therapy in patients with first unprovoked venous thromboembolism

Author

Agudo, P., Aibar, J., Alberich-Conesa, A., Alda-Lozano, A., Alfonso, J., Amado, C., Angelina-García, M., Arcelus, J.I., Ballaz, A., Barba, R., Barbagelata, C., Barreiro, B., Barrón, M., Barrón-Andrés, B., Bascuñana, J., Beddar-Chaib, F., Blanco-Molina, A., Caballero, J.C., Cañas, I., Castellanos, G., Chasco, L., Claver, G., Criado, J., De Juana-Izquierdo, C., Del Toro, J., Demelo-Rodríguez, P., Díaz-Pedroche, M.C., Díaz-Peromingo, J.A., Dubois-Silva, A., Escribano, J.C., Falgá, C., Fernández-Aracil, C., Fernández-Capitán, C., Fernández-Jiménez, B., Fernández-Reyes, J.L., Fidalgo, M.A., Francisco, I., Gabara, C., Galeano-Valle, F., García-Bragado, F., García-Ortega, A., Gavín-Sebastián, O., Gil-Díaz, A., Gómez-Cuervo, C., González-Munera, A., Grau, E., Guirado, L., Gutiérrez-Guisado, J., Hernández-Blasco, L., Hernández-Molina, A., Hernández-Vidal, M.J., Jara-Palomares, L., Jiménez, D., Jou, I., Joya, M.D., Lalueza, A., Lecumberri, R., Llamas, P., Lobo, J.L., López-Brull, H., López-De la Fuente, M., López-Jiménez, L., López-Miguel, P., López-Núñez, J.J., López-Ruiz, A., López-Sáez, J.B., Lorente, M.A., Lorenzo, A., Lumbierres, M., Madridano, O., Maestre, A., Marchena, P.J., Marcos, M., Martín del Pozo, M., Martín-Martos, F., Martínez-Prado, R., Maza, J.M., Mercado, M.I., Moisés, J., Molino, A., Monreal, M., Monzón, L., Morales, M.V., Muñoz-Gamito, G., Navas, M.S., Nieto, J.A., Núñez-Fernández, M.J., Olid, M., Ordieres-Ortega, L., Ortiz, M., Osorio, J., Otálora, S., Otero, R., Pacheco-Gómez, N., Pagán, J., Palomeque, A.C., Paredes, E., Parra-Rosado, P., Pedrajas, J.M., Pérez-Ductor, C., Pérez-Pinar, M., Peris, M.L., Pesce, M.L., Porras, J.A., Puchades, R., Rivas, A., Rivera-Cívico, F., Rivera-Gallego, A., Rodríguez-Cobo, A., Romero-Bruguera, M., Ruiz-Artacho, P., Salgueiro, G., Sancho, T., Sendín, V., Sigüenza, P., Soler, S., Steinherr, A., Suárez-Fernández, S., Tirado, R., Torrents-Vilar, A., Torres, M.I., Trujillo-Santos, J., Uresandi, F., Valle, R., Varona, J.F., Villalobos, A., Villares, P., Ay, C., Nopp, S., Pabinger, I., Vanassche, T., Verhamme, P., Verstraete, A., Yoo, H.H.B., Montenegro, A.C., Morales, S.N., Roa, J., Hirmerova, J., Malý, R., Varhaník, F., Bertoletti, L., Bura-Riviere, A., Catella, J., Chopard, R., Couturaud, F., Espitia, O., Le Mao, R., Leclerq, B., Mahé, I., Moustafa, F., Plaisance, L., Sarlon-Bartoli, G., Suchon, P., Versini, E., Schellong, S., Brenner, B., Dally, N., Kenet, G., Tzoran, I., Rashidi, F., Sadeghipour, P., Tahmasbi, F., Abenante, A., Barillari, G., Bilora, F., Bissacco, D., Brandolin, B., Casana, R., Ciammaichella, M., Colaizzo, D., Dentali, F., Di Micco, P., Giorgi-Pierfranceschi, M., Grandone, E., Imbalzano, E., Lambertenghi-Deliliers, D., Martini, R., Meschi, T., Negro, F., Poz, A., Prandoni, P., Simioni, P., Siniscalchi, C., Taflaj, B., Ticinesi, A., Tufano, A., Visonà, A., Zalunardo, B., Kalnina, P., Kigitovica, D., Skride, A., Zicans, M., Nishimoto, Y., Yamashita, Y., Tazi-Mezalek, Z., Fonseca, S., Marques, R., Meireles, J., Pinto, S., Bosevski, M., Zdraveska, M., Bounameaux, H., Mazzolai, L., Aujayeb, A., Bikdeli, B., Caprini, J.A., Khalil, A., Tafur, J., Weinberg, I., Bui, H.M., Nguyen, S.T., Pham, K.Q., Tran, G.B., Gabara, Cristina, Aibar, Jesus, Nishimoto, Yuji, Yamashita, Yugo, Prandoni, Paolo, Barnes, Geoffrey D., Bikdeli, Behnood, Jiménez, David, Demelo-Rodríguez, Pablo, Peris, Ma Luisa, Nguyen, Son Truong, and Monreal, Manuel

Published
2024
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39. Risk of recurrence after discontinuing anticoagulation in patients with COVID-19- associated venous thromboembolism: a prospective multicentre cohort study

Author

Adarraga, María Dolores, Conesa, Ana Alberich, Aibar, Jesús, Lozano, Alicia Alda, Alfonso, Joaquín, Carrillo, Jesús Alonso, Amado, Cristina, García, María Angelina, Arcelus, Juan Ignacio, Ballaz, Aitor, Barba, Raquel, Hernando, María Barca, Barbagelata, Cristina, Barrón, Manuel, Andrés, Belén Barrón, Chaib, Fahd Beddar, Blanco Molina, María Ángeles, Caballero, Juan Carlos, Castellanos, Gonzalo, Chasco, Leyre, Criado, Juan, de Ancos, Cristina, Toro, Jorge del, Rodríguez, Pablo Demelo, de Juana Izquierdo, Cristina, Díaz Brasero, Ana María, Díaz Peromingo, José Antonio, Silva, Álvaro Dubois, Escribano, Juan Carlos, Falgá, Concepción, Farfán Sedano, Ana Isabel, Aracil, Cleofe Fernández, Capitán, Carmen Fernández, Jiménez, Begoña Fernández, Fernández Reyes, José Luis, Fidalgo, María Ángeles, Francisco, Iria, Gabara, Cristina, Valle, Francisco Galeano, Bragado, Francisco García, Ortega, Alberto García, Sebastián, Olga Gavín, Gil de Gómez, María Allende, Díaz, Aída Gil, Cuervo, Covadonga Gómez, Munera, Adriana González, Grau, Enric, Guirado, Leticia, Gutiérrez, Javier, Blasco, Luis Hernández, Palomares, Luis Jara, Jaras, María Jesús, Jiménez, David, Jiménez, Rafael, Jou, Inés, Joya, María Dolores, Justo, Sara Lainez, Lalueza, Antonio, Lecumberri, Ramón, León Ramírez, José Manuel, Llamas, Pilar, Lobo, José Luis, Jiménez, Luciano López, Miguel, Patricia López, López Núñez, Juan José, Ruiz, Antonio López, López Sáez, Juan Bosco, Lorenzo, Alicia, Lumbierres, Marina, Madridano, Olga, Maestre, Ana, Marchena, Pablo Javier, Marcos, María, Martín del Pozo, Mar, Martos, Francisco Martín, Maza, Jorge Manuel, Mena, Elisabeth, Mercado, Maria Isabel, Moisés, Jorge, Monreal, Manuel, Morales, María del Valle, Navas, Maria Sierra, Nieto, José Antonio, Núñez Fernández, Manuel Jesús, Olid, Mónica, Ortega, Lucía Ordieres, Ortiz, María, Osorio, Jeisson, Otálora, Sonia, Otero, Remedios, Gómez, Nazaret Pacheco, Pagán, Javier, Palomeque, Andrea Catalina, Paredes, Ezequiel, Caballero, Pedro Parra, Pedrajas, José María, Ductor, Cristina Pérez, Pinar, Montserrat Pérez, Peris, María Luisa, Pesce, María Lourdes, Porras, José Antonio, Puchades, Ramón, Cívico, Francisco Rivera, Cobo, Ana Rodríguez, Rosa, Vladimir, Brugera, Marta Romero, Artacho, Pedro Ruiz, Giménez, Nuria Ruiz, Ruiz, Justo Ruiz, Salgueiro, Georgina, Sancho, Teresa, Sendín, Vanesa, Sigüenza, Patricia, Soler, Silvia, Fernández, Susana Suárez, Tirado, Raimundo, Vilar, Ana Torrents, Torres, María Isabel, Santos, Javier Trujillo, Uresandi, Fernando, Valle, Reina, Varona, José Felipe, Villalobos, Aurora, Villares, Paula, Ay, Cihan, Nopp, Stephan, Pabinger, Ingrid, Engelen, Matthias, Vanassche, Thomas, Verhamme, Peter, Bok Yoo, Hugo Hyung, Montenegro, Ana Cristina, Morales, Silvia Natalia, Roa, Jairo, Hirmerova, Jana, Malý, Radovan, Bertoletti, Laurent, Bura-Riviere, Alessandra, Catella, Judith, Chopard, Romain, Couturaud, Francis, Espitia, Olivier, Grange, Claire, Leclercq, Barbara, Le Mao, Raphael, Mahé, Isabelle, Moustafa, Farès, Plaisance, Ludovic, Bartoli, Gabrielle Sarlon, Suchon, Pierre, Versini, Edouard, Schellong, Sebastian, Brenner, Benjamin, Dally, Najib, Tzoran, Inna, Sadeghipour, Parham, Rashidi, Fahrid, Abenante, Alessia, Barillari, Giovanni, Basaglia, Manuela, Bilora, Franca, Bissacco, Daniele, Bortoluzzi, Cristiano, Brandolin, Barbara, Casana, Renato, Ciammaichella, Maurizio, Colaizzo, Donatella, Dentali, Francesco, Di Micco, Pierpaolo, Grandone, Elvira, Imbalzano, Egidio, Deliliers, Daniela Lambertenghi, Negro, Federica, Pesavento, Raffaele, Poz, Alessandra, Prandoni, Paolo, Scarinzi, Paolo, Siniscalchi, Carmine, Taflaj, Beldisa, Tufano, Antonella, Visonà, Adriana, Hong, Ngoc Vo, Zalunardo, Beniamino, Skride, Andris, Kigitovica, Dana, Fonseca, Samuel, Marques, Rafael, Meireles, José, Pinto, Sara Barbosa, Bosevsky, Marijan, Eftimova, Aleksandra, Zdraveska, Marijan, Bounameaux, Henri, Mazzolai, Lucia, Aujayeb, Avinash, Bikdeli, Behnood, Caprini, Joseph, Weinberg, Ido, Bui, Hanh My, Jara-Palomares, Luis, Muriel, Alfonso, Demelo-Rodríguez, Pablo, López-Miguel, Patricia, López-Jiménez, Luciano, and Rivera-Cívico, Francisco

Published
2024
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40. Traduction et republication de : « Traitement de la maladie thromboembolique veineuse associée au cancer chez les patients en soins palliatifs »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Rouge Bugat, M.-È., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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43. Traduction et republication de : « Prise en charge de la maladie thromboembolique veineuse associée au cancer chez les populations vulnérables »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Rouge Bugat, M.-È., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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44. Traduction et republication de : « Thrombose veineuse profonde du membre supérieur associée à un cathéter veineux central chez les patients cancéreux : diagnostic et prise en charge thérapeutique »

Author

Benhamou, Y., Benmaziane, A., Bertoletti, L., Bichon, V., Bozec, C., Cohen, A., Couturaud, F., Debourdeau, P., Dielenseger, P., Douriez, É., Élias, A., Espitia, O., Frère, C., Gaboreau, Y., Gendron, P., Girard, P., Hanon, O., Idbaih, A., Laporte, S., Mahé, I., Mayeur, D., Mismetti, P., Moustafa, F., Pernod, G., Roy, P.-M., Rouge Bugat, M.-È., Sanchez, O., Schmidt, J., Scotté, F., and Sevestre, M.-A.

Published
2024
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