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1. Liste des collaborateurs

Author

Aboyans, Victor, primary, Abraham, Pierre, additional, Aïchoun, Isabelle, additional, Albertini, Jean-Noël, additional, Amar, Laurence, additional, Ammi, Myriam, additional, Azizi, Michel, additional, Azzaoui, Richard, additional, Bartoli, Michel Alain, additional, Baud, Jean-Michel, additional, Becker, François, additional, Belaye, Lavinia, additional, Böge, Gudrun, additional, Boissier, Christian, additional, Bongard, Vanina, additional, Bonnin, Christophe, additional, Bouilly, Patrick, additional, Boulon, Carine, additional, Boutouyrie, Pierre, additional, Bressollette, Luc, additional, Brizzi, Sophie, additional, Brochériou, Isabelle, additional, Bura-Rivière, Alessandra, additional, Cacoub, Patrice, additional, Calanca, Luca, additional, Carpentier, Patrick-Henri, additional, Chaufour, Xavier, additional, Chavent, Bertrand, additional, Chiche, Laurent, additional, Clin-Godard, Bénédicte, additional, Cohen, Serge, additional, Constans, Joël, additional, Couture, Thibaut, additional, Dadon, Michel, additional, Daoudal, Anne, additional, Dauzat, Michel, additional, Depairon, Michèle, additional, Desormais, Ileana, additional, Deverly, Anne Blanchet, additional, Di Rienzo-Ambrozkiewicz, Monika, additional, Duprey, Ambroise, additional, Éveno-Saunier, Clarisse, additional, Fabre, Dominique, additional, Favre, Jean-Pierre, additional, Ferrari, Béatrice, additional, Fogeron, Claire-Lise, additional, Frank, Michael, additional, Galanaud, Jean-Philippe, additional, Garrigues, Damien, additional, Gautier, Valentine, additional, Gestin, Simon, additional, Giordana, Pascal, additional, Gouëffic, Yann, additional, Grenier, Nicolas, additional, Guilmot, Jean-Louis, additional, Guiraut, Thibaut, additional, Haase-Ruby, Caroline, additional, Haulon, Stéphan, additional, Heller, Fabien, additional, Hertault, Adrien, additional, Houmaida, Hassan, additional, Jaquinandi, Vincent, additional, Jean-Baptiste, Elixène, additional, Kaladji, Adrien, additional, Khettab, Hakim, additional, Klotz, Rémi, additional, Koskas, Fabien, additional, Lacroix, Philippe, additional, Lambert, Marc, additional, Laroche, Jean-Pierre, additional, Larrue, Vincent, additional, Laskar (†), Marc, additional, Laurian, Claude, additional, Lazareth, Isabelle, additional, Le Hello, Claire, additional, Lebas, Benoit, additional, Long, Anne, additional, Luizy (†), François, additional, Magne, Jean-Luc, additional, Mahé, Guillaume, additional, Martin, Romain, additional, Martin-Gonzalez, Teresa, additional, Maufus, Mario, additional, Mazzolai, Lucia, additional, Messas, Emmanuel, additional, Meyrignac, Olivier, additional, Midy, Dominique, additional, Mirault, Tristan, additional, Mokaddem, Wassim, additional, Mokrane, Fatima-Zohra, additional, Patra (†), Philippe, additional, Pérez-Martin, Antonia, additional, Pernod, Gilles, additional, Pesteil, Francis, additional, Petermann, Antoine, additional, Petrissans-Ferrando, Nicole, additional, Picquet, Jean, additional, Pirvu, Augustin, additional, Pistorius, Marc-Antoine, additional, Poggi, Jean-Noël, additional, de Préville, Agathe, additional, Priollet, Pascal, additional, Quéhé, Philippe, additional, Quéré, Isabelle, additional, Revel-Mouroz, Paul, additional, Rousseau, Hervé, additional, Saadoun, David, additional, Sandrin-Berthon, Brigitte, additional, Sanson, Hélène, additional, Sarlon-Bartoli, Gabrielle, additional, Satger, Bernadette, additional, Schuster, Iris, additional, Seinturier, Christophe, additional, Sene, Damien, additional, Senet, Patricia, additional, Sevestre, Marie-Antoinette, additional, Siddique, Salma, additional, Sobocinski, Jonathan, additional, Spear, Rafaelle, additional, Sprynger, Muriel, additional, Steinmetz, Éric, additional, Stephan, Dominique, additional, Wahl, Denis, additional, Wennberg, Paul Wade, additional, Yelnik, Cécile, additional, and Zuily, Stéphane, additional

Published
2016
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4. Liste des auteurs

Author

Aboyans, Victor, primary, Abud, T., additional, Albertini, Jean-Noël, additional, Alhenc-Gelas, Martine, additional, Allaire, Éric, additional, Amar, Laurence, additional, Azema, Laure, additional, Azizi, Michel, additional, Auvert, Jean-François, additional, Avouac, Julien, additional, Aymard, Armand, additional, Barral, Xavier, additional, Barthelemy, Pierre, additional, Baud, Jean-Michel, additional, Baudoin, Patrice, additional, Becker, François, additional, Ben Ahmed, S., additional, Berard, Annie, additional, Bereau, Estelle, additional, Bertoletti, Laurent, additional, Bigorre, Michèle, additional, Biland, Guillaume, additional, Bisdorff-Bresson, Annouk, additional, Blaise, Sophie, additional, Blum, Alain, additional, Böge, Gudrun, additional, Boisseau, Michel Robert, additional, Boissier, Christian, additional, Bonnet, Vincent, additional, Bonnin, Christophe, additional, Bossavy, Jean-Pierre, additional, Bouilly, Patrick, additional, Boulon, Carine, additional, Branchereau, Alain, additional, Bregeaud, Delphine, additional, Bressollette, Luc, additional, Breviere, Georges-Marie, additional, Brisbois, Denis, additional, Brisset, D., additional, Brocheriou, Isabelle, additional, Bruneval, Patrick, additional, Cottentin, Olivier, additional, Bura-Riviere, Alessandra, additional, Cacoub, Patrice, additional, Cambou, Jean-Pierre, additional, Camelot, Gabriel, additional, Carpentier, Patrick, additional, Cauchy, Emmanuel, additional, Chammas, Michel, additional, Chaufour, Xavier, additional, Chiche, Laurent, additional, Clin-Godard, B., additional, Conard, Jacqueline, additional, Connes, Philippe, additional, Conri, Claude, additional, Constans, Joël, additional, Coppé, Gérard, additional, Coulon, Paul, additional, Coupé, Marlène, additional, Cremer, Antoine, additional, Creton, Denis, additional, Creton, Olivier, additional, Dahan, Philippe, additional, Dallongeville, Jean, additional, Dautzenberg, Bertrand, additional, Dauzat, Michel, additional, de Wilde, Jean-Philippe, additional, Debourdeau, Philippe, additional, Debure, Clélia, additional, Decousus, Hervé, additional, Degrullier-Chopinet, Caroline, additional, Dehant, Véronique, additional, Deklunder, Ghyslaine, additional, Delluc, Aurélien, additional, Delsart, Pascal, additional, Diot, Elisabeth, additional, Dulac, Yves, additional, Duprey, Ambroise, additional, Durant, C., additional, Duthois, Sylvain, additional, El Jaouhari, Asma, additional, Elias, Antoine, additional, Elias, Marie, additional, Emmerich, Joseph, additional, Esnault, Vincent, additional, Farge-Bancel, Dominique, additional, Farnier, Michel, additional, Faure, Sébastien, additional, Favre, Jean-Pierre, additional, Ferreira-Maldent, Nicole, additional, Ferrieres, Jean, additional, Fiessinger, Jean-Noël, additional, Flaujac, Claire, additional, Fontana, Pierre, additional, Frank, Michael, additional, Frederic, Muriel, additional, Gagnon, Nathalie, additional, Gardet, Emmanuel, additional, Garrigues, Damien, additional, Gerard, Jean-Luc, additional, Gigou, F., additional, Girerd, Xavier, additional, Goret, Lucie, additional, Gosse, Philippe, additional, Grenier, Nicolas, additional, Grimaldi, André, additional, Guibaud, Laurent, additional, Guillevin, Loïc, additional, Guilmot, Jean-Louis, additional, Haase, Caroline, additional, Hachulla, Éric, additional, Halbron, Marine, additional, Hamel-Desnos, Claudine, additional, Hammel, Jonathan, additional, Hanon, Olivier, additional, Hatron, Pierre-Yves, additional, Hermier, Marc, additional, Horellou, Marie-Hélène, additional, Houdart, Emmanuel, additional, Khau van Kien, Aurélie, additional, Kieffer, Edouard, additional, Koskas, Fabien, additional, Kretz, Jean-Georges, additional, Labau, Diane, additional, Lacroix, Philippe, additional, Lacut, Karine, additional, Laffont, Joëlle-Yvette, additional, Lambert, Marc, additional, Laroche, Jean-Pierre, additional, Larrue, Vincent, additional, Laskar, Marc, additional, Lasry, Jean-Louis, additional, Laurian, Claude, additional, Lazareth, Isabelle, additional, Le Bras, Yann, additional, Le Gal, Grégoire, additional, Le Hello, Claire, additional, Le Thi Huong, D., additional, Lecompte, Thomas, additional, Leftheriotis, Georges, additional, Lemarchand-Venencie, F., additional, Lemasle, Philippe, additional, Letombe, Brigitte, additional, Levesque, Hervé, additional, Long, Anne, additional, Luizy, François (†), additional, Magnan, Pierre-Edouard, additional, Magnant, Julie, additional, Mallios, A., additional, Marchand-Adam, Sylvain, additional, Marie, Isabelle, additional, Martinez, Carmen, additional, Maumias, T., additional, Meaume, Sylvie, additional, Messas, Emmanuel, additional, Mestre, Sandrine, additional, Meyer, Guy, additional, Midy, Dominique, additional, Mismetti, Patrick, additional, Mollard, Jean-Marc, additional, Montaudon, Michel, additional, Moraglia, Luc, additional, Mottier, Dominique, additional, Mounier-Vehier, Claire, additional, Moyou-Mogo, Roger, additional, Nicolini, Philippe, additional, Nourrissat, Ghislain, additional, Ouvry, Pierre, additional, Patra, Philippe, additional, Perez Martin, Antonia, additional, Pernes, Jean-Marc, additional, Pernod, Gilles, additional, Perret-Guillaume, Christine, additional, Perrin, Michel, additional, Pesteil, Francis, additional, Pichot, Olivier, additional, Pistorius, Marc-Antoine, additional, Planchon, Bernard, additional, Plouin, Pierre-François, additional, Poggi, Jean-Noël, additional, Priollet, Pascal, additional, Quehe, Philippe, additional, Quere, Isabelle, additional, Ramelet, Albert-Adrien, additional, Renaudin, Jean-Marc, additional, Reny, Jean-Luc, additional, Righini, Marc, additional, Rosenbaum, David, additional, Rosset, Eugenio, additional, Roy, Pierre-Marie, additional, Saadi, Leilah, additional, Saby, Jean-Claude, additional, Samama, Meyer Michel, additional, Sandrin-Berthon, Brigitte, additional, Satger-Gouin, Bernardette, additional, Iris, Schuster-Beck, additional, Segard, Magali, additional, Sene, Damien, additional, Senet, Patricia, additional, Serise, Jean Michel, additional, Sessa, Carmine, additional, Sevestre-Pietri, Marie-Antoinette, additional, Sirvente, Jérôme, additional, Solanilla, Anne, additional, Soulier-Sotto, Virginie, additional, Sprynger, Muriel, additional, Stephan, Dominique, additional, Sussman, Hélène, additional, Tanguy, Bénédicte, additional, Terriat, Béatrice, additional, Thiebaugeorges, Olivier, additional, Thomas, Daniel, additional, Tribout, Laurent, additional, Turpault, Jean-Philippe, additional, Vaillant, Loïc, additional, Van Cleef, Jean-François, additional, Vayssairat, Michel, additional, Vernhet-Kovasick, Hélène, additional, Vicaut, Éric, additional, Vignes, Stéphane, additional, Villeneuve, Frédéric, additional, Viremouneix, Loïc, additional, Wahl, Denis, additional, Warembourg, Frédérique, additional, Wautrecht, Jean-Claude, additional, Wechsler, Bertrand, additional, and Zuily, Stéphane, additional

Published
2011
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5. Liste des Auteurs

Author

Constans, Joël, primary, Aboyans, Victor, additional, Abud, T., additional, Albertini, Jean-Noël, additional, Alhenc-Gelas, Martine, additional, Allaire, Eric, additional, Amar, Laurence, additional, Azema, Laure, additional, Azizi, Michel, additional, Auvert, Jean-François, additional, Avouac, Julien, additional, Aymard, Armand, additional, Barral, Xavier, additional, Barthelemy, Pierre, additional, Baud, Jean-Michel, additional, Hôpital, André Mignot, additional, Baudoin, Patrice, additional, Becker, François, additional, Ben Ahmed, S., additional, Berard, Annie, additional, Bereau, Estelle, additional, Bertoletti, Laurent, additional, Bigorre, Michèle, additional, Biland, Guillaume, additional, Bisdorff-Bresson, Annouk, additional, Blaise, Sophie, additional, Blum, Alain, additional, Böge, Gudrun, additional, Boisseau, Michel R., additional, Boissier, Christian, additional, Bonnet, Vincent, additional, Bonnin, Christophe, additional, Bossavy, Jean-Pierre, additional, Bouilly, Patrick, additional, Boulon, Carine, additional, Branchereau, Alain, additional, Bregeaud, Delphine, additional, Bressollette, Luc, additional, Breviere, Georges-Marie, additional, Brisbois, Denis, additional, Brisset, D., additional, Brocheriou, Isabelle, additional, Bruneval, Patrick, additional, Bura-Riviere, Alessandra, additional, Cacoub, Patrice, additional, Cambou, Jean-Pierre, additional, Camelot, Gabriel, additional, Carpentier, Patrick, additional, Cauchy, Emmanuel, additional, Chammas, Michel, additional, Chaufour, Xavier, additional, Chiche, Laurent, additional, Clin-Godard, Bénédicte, additional, Conard, Jacqueline, additional, Connes, Philippe, additional, Conri, Claude, additional, Constans, Joël, additional, Coppé, Gérard, additional, Cottentin, Olivier, additional, Coulon, Paul, additional, Coupé, Marlène, additional, Cremer, Antoine, additional, Creton, Denis, additional, Creton, Olivier, additional, Dahan, Philippe, additional, Dallongeville, Jean, additional, Dautzenberg, Bertrand, additional, Dauzat, Michel, additional, De Wilde, Jean-Philippe, additional, Debourdeau, Philippe, additional, Debure, Clélia, additional, Decousus, Hervé, additional, Degrullier-Chopinet, Caroline, additional, Dehant, Véronique, additional, Deklunder, Ghyslaine, additional, Delluc, Aurélien, additional, Delsart, Pascal, additional, Diot, Elisabeth, additional, Dulac, Yves, additional, Duprey, Ambroise, additional, Durant, C., additional, Duthois, Sylvain, additional, El Jaouhari, Asma, additional, Elias, Antoine, additional, Elias, Marie, additional, Emmerich, Joseph, additional, Esnault, Vincent, additional, Farge-Bancel, Dominique, additional, Farnier, Michel, additional, Faure, Sébastien, additional, Favre, Jean-Pierre, additional, Ferreira-Maldent, Nicole, additional, Ferrieres, Jean, additional, Fiessinger, Jean-Noel, additional, Flaujac, Claire, additional, Fontana, Pierre, additional, Frank, Michael, additional, Frederic, Muriel, additional, Gagnon, Nathalie, additional, Gardet, Emmanuel, additional, Garrigues, Damien, additional, Gerard, Jean-Luc, additional, Gigou, Frédéric, additional, Girerd, Xavier, additional, Goret, Lucie, additional, Gosse, Philippe, additional, Grenier, Nicolas, additional, Grimaldi, André, additional, Guibaud, Laurent, additional, Guillevin, Loïc, additional, Guilmot, Jean-Louis, additional, Haase, Caroline, additional, Hachulla, Eric, additional, Halbron, Marine, additional, Hamel-Desnos, Claudine, additional, Hammel, Jonathan, additional, Hanon, Olivier, additional, Hatron, Pierre-Yves, additional, Hermier, Marc, additional, Horellou, Marie-Hélène, additional, Houdart, Emmanuel, additional, Khau Van Kien, Aurélie, additional, Kieffer, Edouard, additional, Koskas, Fabien, additional, Kretz, Jean-Georges, additional, Labau, Diane, additional, Lacroix, Philippe, additional, Lacut, Karine, additional, Laffont, Joëlle-Yvette, additional, Lambert, Marc, additional, Chru, de Lille, additional, Laroche, Jean-Pierre, additional, Larrue, Vincent, additional, Laskar, Marc, additional, Laurian, Claude, additional, Lazareth, Isabelle, additional, Le Bras, Yann, additional, Le Gal, Grégoire, additional, Le Hello, Claire, additional, Le Thi Huong, Du, additional, Lecompte, Thomas, additional, Leftheriotis, Georges, additional, Lemarchand-Venencie, Françoise, additional, Lemasle, Philippe, additional, Letombe, Brigitte, additional, Levesque, Hervé, additional, Long, Anne, additional, Luizy, François, additional, Magnan, Pierre-Edouard, additional, Magnant, Julie, additional, Mallios, Alexandros, additional, Marchand-Adam, Sylvain, additional, Marie, Isabelle, additional, Martinez, Carmen, additional, Maumias, Thibault, additional, Meaume, Sylvie, additional, Messas, Emmanuel, additional, Mestre, Sandrine, additional, Meyer, Guy, additional, Midy, Dominique, additional, Mismetti, Patrick, additional, Mollard, Jean-Marc, additional, Montaudon, Michel, additional, Moraglia, Luc, additional, Mottier, Dominique, additional, Mounier-Vehier, Claire, additional, Moyou-Mogo, Roger, additional, Nicolini, Philippe, additional, Nourrissat, Ghislain, additional, Ouvry, Pierre, additional, Patra, Philippe, additional, Perez Martin, Antonia, additional, Pernes, Jean-Marc, additional, Pernod, Gilles, additional, Perret-Guillaume, Christine, additional, Perrin, Michel, additional, Pesteil, Francis, additional, Pichot, Olivier, additional, Pistorius, Marc-Antoine, additional, Planchon, Bernard, additional, Plouin, Pierre-François, additional, Poggi, Jean-Noël, additional, Priollet, Pascal, additional, Quehe, Philippe, additional, Quere, Isabelle, additional, Ramelet, Albert-Adrien, additional, Renaudin, Jean-Marc, additional, Reny, Jean-Luc, additional, Righini, Marc, additional, Rosenbaum, David, additional, Rosset, Eugenio, additional, Roy, Pierre-Marie, additional, Saadi, Leilah, additional, Saby, Jean-Claude, additional, Samama, Meyer Michel, additional, Sandrin-Berthon, Brigitte, additional, Satger-Gouin, Bernardette, additional, Schuster-Beck, Iris, additional, Chu, de Montpellier, additional, Segard, Magali, additional, Sene, Damien, additional, Senet, Patricia, additional, Serise, Jean Michel, additional, Sessa, Carmine, additional, Sevestre-Pietri, Marie-Antoinette, additional, Sirvente, Jérôme, additional, Solanilla, Anne, additional, Soulier-Sotto, Virginie, additional, Sprynger, Muriel, additional, Stephan, Dominique, additional, Sussman, Hélène, additional, Tanguy, Bénédicte, additional, Terriat, Béatrice, additional, Thiebaugeorges, Olivier, additional, Thomas, Daniel, additional, Tribout, Laurent, additional, Turpault, Jean-Philippe, additional, Vaillant, Loïc, additional, Van Cleef, Jean-François, additional, Vayssairat, Michel, additional, Vernhet-Kovasick, Hélène, additional, Vicaut, Eric, additional, Vignes, Stéphane, additional, Villeneuve, Frédéric, additional, Viremouneix, Loïc, additional, Wahl, Denis, additional, Warembourg, Frédérique, additional, Wautrecht, Jean Claude, additional, Wechsler, Bertrand, additional, and Zuily, Stéphane, additional

Published
2010
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9. [Dental carie as chronic disease, a new therapeutic approach.]

Author

Trentesaux , Thomas, Sandrin-Berthon , Brigitte, Stuckens , Chantal, Hamel , Olivier, Hervé , Christian, Laboratoire d'éthique médicale et médecine légale (LEM), Université Paris Descartes - Paris 5 (UPD5), Département d'odontologie pédiatrique, Université de Lille, Droit et Santé, Direction de la formation 'Diabète éducation de langue française', Haut Conseil de la Santé Publique (HCSP), Pédiatrie-diabétologie, Hôpital Jeanne de Flandre [Lille], Département de santé publique, Faculté de chirurgie dentaire de Toulouse, Laboratoire d'éthique médicale et médecine légale ( LEM ), Université Paris Descartes - Paris 5 ( UPD5 ), Haut Conseil de Santé Publique, Faculté de chirurgie dentaire, Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, and Duchange, Nathalie

Subjects
stomatognathic diseases, Patient Education as Topic, stomatognathic system, Chronic Disease, [ SDV.ETH ] Life Sciences [q-bio]/Ethics, Humans, Dental Caries, [SDV.ETH] Life Sciences [q-bio]/Ethics, [SDV.ETH]Life Sciences [q-bio]/Ethics
Abstract

International audience; For many decades, oral health has been improving considerably in France. Caries indicators have decreased strongly. However, some "high risk" populations accumulate the majority of tooth decay. For them, health education and public health policies are inefficient. Tooth decay starts early and continues throughout their lives. Describing dental caries as a chronic pathology enables us to envisage alternative therapies, such as therapeutic patient education.

Published
2011

10. A therapeutic education programme for diabetic children : recreational, creative methods, and use of puppets

Author

UCL - MD/ESP - Ecole de santé publique, Pélicand, Julie, Gagnayre, Rémi, Sandrin-Berthon, Brigitte, Aujoulat, Isabelle, UCL - MD/ESP - Ecole de santé publique, Pélicand, Julie, Gagnayre, Rémi, Sandrin-Berthon, Brigitte, and Aujoulat, Isabelle

Abstract

Patient education is an important aspect of care to young diabetic children. The use of playthings and recreational activities is an effective way to help children develop harmoniously by integrating the paradox of having to become compliant with treatment and medication while becoming autonomous in life. This paper presents the evaluation of a therapeutic education programme which was attended by 14 young diabetic patients aged 10-12. In order to take into account the learning capacities and strategies linked to the children's age and development stage, the programme's methods were mainly interactive and recreational. In particular, puppets were used as a means to enable the children to express themselves on different aspects of diabetes-related difficulties in their everyday life. The results of the study show that recreational methods and tools can effectively be implemented into therapeutic patient education programmes so as to enable children to develop various treatment-related skills. As far as the psychosocial skill of expressing one's difficulties and emotions is concerned, the use of puppets was found to be an effective means to facilitate the development of such a skill. Moreover, puppets were found to have a projective and transactional function that allowed children to make decisions and react autonomously, and thus regain control on situations in which they had previously felt disempowered.

Published
2006

12. Exclusion et sciences humaines. Exclusions en sciences humaines

Author

UCL - (SLuc) Autre, Grawez, Michel, Greimans, Sophie, Biname, Jean-Pierre, Libion, France, Doumont, Dominique, Sandrin-Berthon, Brigitte, Favresse, Damien, Jamin, Jérôme, Barras, Christine, UCL - (SLuc) Autre, Grawez, Michel, Greimans, Sophie, Biname, Jean-Pierre, Libion, France, Doumont, Dominique, Sandrin-Berthon, Brigitte, Favresse, Damien, Jamin, Jérôme, and Barras, Christine

Published
2002

16. Apprendre la santé à l'école / Brigitte Sandrin Berthon

Author

Sandrin Berthon, Brigitte. Auteur du texte and Sandrin Berthon, Brigitte. Auteur du texte

Abstract

Collection : Pratiques & enjeux pédagogiques, Collection : Pratiques & enjeux pédagogiques, Contient une table des matières, Avec mode texte

Published
1997

24. Bile acids mobilise internal Ca2+ independently of external Ca2+ in rat hepatocytes.

Author

Combettes, Laurent, Berthon, Brigitte, Doucet, Edith, Erlinger, Serge, and Claret, Michel

Subjects
*BILE acids, *CALCIUM, *RATS, *LIVER cells, *ANIMAL models in research, *BIOCHEMISTRY
Abstract

In the present study, we investigated the possible role of external Ca2+ in the rise of the cytosolic Ca+ concentration induced by the monohydroxy bile acid taurolithocholate in isolated rat liver cells. The results showed that: (a) the bile acid promotes the same dose-dependent increase in the cytosolic Ca+ concentration (half-maximal effect at 23 μM) in hepatocytes incubated in the presence of 1.2 mM Ca2+ or 6 μM Ca2+; (b) taurolithocholate is able to activate the Ca2+-dependent glycogen phosphorylase a by 6.3-fold and 6.0-fold in high and low Ca2+ media, respectively; (c) [14C]taurolithocholate influx is not affected by external Ca2+, and 45Ca2+ influx is not altered by taurolithocholate. These results establish that the effects of taurolithocholate on cell Ca2+ do not require extracellular Ca2+ and are consistent with the view that monohydroxy bile acids primarily release Ca2+ from the endoplasmic reticulum in the liver. [ABSTRACT FROM AUTHOR]

Published
1990
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25. Coordinated intercellular calcium waves induced by noradrenaline in rat hepatocytes: dual control by gap junction permeability and agonist.

Author

Tordjmann, Thierry, Berthon, Brigitte, Claret, Michel, and Combettes, Laurent

Subjects
*CALCIUM, *GAP junctions (Cell biology), *LIVER cells, *INTRACELLULAR pathogens, *NORADRENALINE, *ENDOPLASMIC reticulum
Abstract

Calcium-mobilizing agonists induce intracellular Ca2+ concentration ([Ca2+]i) changes thought to trigger cellular responses. In connected cells, rises in [Ca2+]i can propagate from cell to cell as intercellular Ca2+ waves, the mechanisms of which are not elucidated. Using fura2-loaded rat hepatocytes, we studied the mechanisms controlling coordination and intercellular propagation of noradrenaline-induced Ca2+ signals. Gap junction blockade with 18 α-glycyrrhetinic acid resulted in a loss of coordination between connected cells. We found that second messengers and [Ca2+]i rises in one hepatocyte cannot trigger Ca2+ responses in connected cells, suggesting that diffusion across gap junctions, while required for coordination, is not sufficient by itself for the propagation of intercellular Ca2+ waves. In addition, our experiments revealed functional differences between noradrenaline-induced Ca2+ signals in connected hepatocytes. These results demonstrate that intercellular Ca2+ signals in multicellular systems of rat hepatocytes are propagated and highly organized through complex mechanisms involving at least three factors. First, gap junction coupling ensures coordination of [Ca2+]i oscillations between the different cells; second, the presence of hormone at each hepatocyte is required for cell—cell Ca2+ signal propagation; and third, functional differences between adjacent connected hepatocytes could allow a ‘pacemaker-like’ intercellular spread of Ca2+ waves. [ABSTRACT FROM AUTHOR]

Published
1997
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26. Phospholipidic second messengers and calcium

Author

Laurent Combettes, Berthon Brigitte, and Michel Claret

Subjects
Neurotransmitter Agents, chemistry.chemical_element, Cell Communication, General Medicine, Biology, Calcium, Phosphatidylinositols, Biochemistry, Cell biology, chemistry.chemical_compound, Cytosol, chemistry, Second messenger system, Animals, Humans, lipids (amino acids, peptides, and proteins), Inositol, Secretion, Receptor, Visual phototransduction, Diacylglycerol kinase
Abstract

A number of signal molecules bind to surface receptors of target cells and generate intracellular messengers from inositol-containing phospholipids. The phosphatidyl inositol (4, 5) bisphosphate is hydrolyzed into inositol (1, 4, 5) trisphosphate and diacylglycerol. These messengers, via changes in the concentrations of cytosolic Ca2+ and H+ and/or protein phosphorylations, couple the signal to a variety of responses including activation of metabolism, secretion, aggregation, phototransduction, cell proliferation and possibly contraction.

Published
1987

27. Cytosolic free Ca 2+in isolated rat hepatocytes as measured by quin2

Author

Berthon, Brigitte, Binet, Adrien, Mauger, Jean-Pierre, and Claret, Michel

Abstract

Cytosolic [Ca 2+] has been measured by using the Ca 2+-sensitive indicator quin2 in rat liver cells. Optimal loading and hydrolysis have been obtained by equilibrating the cells with 50 μM quin2 acetoxymethyl ester for 150 s. The increase in [Ca 2+] iinitiated by noradrenaline and vasopressin was reduced but not abolished by removing external Ca 2+.

Published
1984
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30. Effect of the bile acid taurolithocholate on cell calcium in saponin-treated rat hepatocytes

Author

Combettes, Laurent, Dumont, Micheline, Berthon, Brigitte, Erlinger, Serge, and Claret, Michel

Abstract

Neomycin was used to assess the involvement of Ins (1,4,5)P 3in the Ca 2+release from the endoplasmic reticulum induced by the bile acid taurolithocholate. In saponin-permeabilized rat hepatocytes, neomycin via its ability to bind Ins (1,4,5)P 3abolished the release of Ca 2+induced by added Ins (1,4,5)P 3. In contrast, it did not alter the Ca 2+release initiated by the bile acid. In intact cells, neomycin had no effect on the [Ca 2+] irises promoted by taurolithocholate and vasopressin. It is suggested that the effect of taurolithocholate in liver is not mediated by Ins (1,4,5)P 3but results from a primary action on endoplasmic reticulum.

Published
1988
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31. Fluxes and distribution of calcium in rat liver cells: kinetic analysis and identification of pools

Author

Claret-Berthon, Brigitte, Claret, M., and Mazet, J. L.

Abstract

1. Fluxes and distribution of Ca were studied in the perfused rat liver. Kinetic analysis of 45Ca exchange revealed three compartments with time constants of 4, 14 and 223 min, pool sizes of 250, 385 and 670 μmole.kg−1wet wt. respectively, and one non‐exchangeable compartment of 400 μmole.kg−1.

Published
1977
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32. Effects of sulphonylureas on cAMP-stimulated Cl− transport via the cystic fibrosis gene product in human epithelial cells

Author

Hongre, Anne -Sophie, Baró, Isabelle, Berthon, Brigitte, and Escande, Denis

Abstract

The cystic fibrosis gene product (CFTR) is a Cl- channel that possesses specific binding sites for cytosolic adenosine triphosphate (ATP) and is activated by cyclic adenosine monophosphate (cAMP)-dependent protein kinases. We explored the possibility that CFTR shares a common pharmacology with another ATP-regulated channel protein, the ATP-sensitive K+ channel that is blocked by sulphonylureas and activated by diazoxide. cAMP-stimulated Cl- effluxes were measured with 36Cl- in the epithelial cell line T84 which stably expresses CFTR. Neither glibenclamide (30 µM), tolbutamide (1 mM) nor diazoxide (100 µM) significantly affected forskolin-activated 36Cl- effluxes in T84 cells. In patch-clamp experiments, glibenclamide exerted only weak inhibitory effects on the whole-cell currents through CFTR with an IC50 of around 0.1 mM. Tolbutamide at 1 mM, but not at 0.1 mM, blocked a current of small amplitude which reversed near the equilibrium potential for K+ ions. We conclude that sulphonylureas and diazoxide are not effective antagonists of endogenous CFTR Cl- channels.

Published
1994
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33. Cytosolic free Ca2+in isolated rat hepatocytes as measured by quin2

Author

Berthon, Brigitte, Binet, Adrien, Mauger, Jean-Pierre, and Claret, Michel

Abstract

Cytosolic [Ca2+] has been measured by using the Ca2+‐sensitive indicator quin2 in rat liver cells. Optimal loading and hydrolysis have been obtained by equilibrating the cells with 50 μM quin2 acetoxymethyl ester for 150 s. The increase in [Ca2+]iinitiated by noradrenaline and vasopressin was reduced but not abolished by removing external Ca2+.

Published
1984
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34. Effect of the α-agonist noradrenaline on total and 45Ca2+ movements in mitochondria of rat liver cells

Author

Berthon, Brigitte, Poggioli, Josiane, Capiod, Thierry, and Claret, Michel

Abstract

Ca2+ movements triggered by noradrenaline were determined in isolated cells and mitochondria from rat livers. It has been shown that these depend on experimental conditions. In cells incubated in 1.8mm-Ca2+, results suggest that noradrenaline mobilizes Ca2+ from reticulum before releasing Ca2+ from mitochondria.

Published
1981
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43. Liste des Auteurs

Author

Constans, Joël, Aboyans, Victor, Abud, T., Albertini, Jean-Noël, Alhenc-Gelas, Martine, Allaire, Eric, Amar, Laurence, Azema, Laure, Azizi, Michel, Auvert, Jean-François, Avouac, Julien, Aymard, Armand, Barral, Xavier, Barthelemy, Pierre, Baud, Jean-Michel, Hôpital, André Mignot, Baudoin, Patrice, Becker, François, Ben Ahmed, S., Berard, Annie, Bereau, Estelle, Bertoletti, Laurent, Bigorre, Michèle, Biland, Guillaume, Bisdorff-Bresson, Annouk, Blaise, Sophie, Blum, Alain, Böge, Gudrun, Boisseau, Michel R., Boissier, Christian, Bonnet, Vincent, Bonnin, Christophe, Bossavy, Jean-Pierre, Bouilly, Patrick, Boulon, Carine, Branchereau, Alain, Bregeaud, Delphine, Bressollette, Luc, Breviere, Georges-Marie, Brisbois, Denis, Brisset, D., Brocheriou, Isabelle, Bruneval, Patrick, Bura-Riviere, Alessandra, Cacoub, Patrice, Cambou, Jean-Pierre, Camelot, Gabriel, Carpentier, Patrick, Cauchy, Emmanuel, Chammas, Michel, Chaufour, Xavier, Chiche, Laurent, Clin-Godard, Bénédicte, Conard, Jacqueline, Connes, Philippe, Conri, Claude, Coppé, Gérard, Cottentin, Olivier, Coulon, Paul, Coupé, Marlène, Cremer, Antoine, Creton, Denis, Creton, Olivier, Dahan, Philippe, Dallongeville, Jean, Dautzenberg, Bertrand, Dauzat, Michel, De Wilde, Jean-Philippe, Debourdeau, Philippe, Debure, Clélia, Decousus, Hervé, Degrullier-Chopinet, Caroline, Dehant, Véronique, Deklunder, Ghyslaine, Delluc, Aurélien, Delsart, Pascal, Diot, Elisabeth, Dulac, Yves, Duprey, Ambroise, Durant, C., Duthois, Sylvain, El Jaouhari, Asma, Elias, Antoine, Elias, Marie, Emmerich, Joseph, Esnault, Vincent, Farge-Bancel, Dominique, Farnier, Michel, Faure, Sébastien, Favre, Jean-Pierre, Ferreira-Maldent, Nicole, Ferrieres, Jean, Fiessinger, Jean-Noel, Flaujac, Claire, Fontana, Pierre, Frank, Michael, Frederic, Muriel, Gagnon, Nathalie, Gardet, Emmanuel, Garrigues, Damien, Gerard, Jean-Luc, Gigou, Frédéric, Girerd, Xavier, Goret, Lucie, Gosse, Philippe, Grenier, Nicolas, Grimaldi, André, Guibaud, Laurent, Guillevin, Loïc, Guilmot, Jean-Louis, Haase, Caroline, Hachulla, Eric, Halbron, Marine, Hamel-Desnos, Claudine, Hammel, Jonathan, Hanon, Olivier, Hatron, Pierre-Yves, Hermier, Marc, Horellou, Marie-Hélène, Houdart, Emmanuel, Khau Van Kien, Aurélie, Kieffer, Edouard, Koskas, Fabien, Kretz, Jean-Georges, Labau, Diane, Lacroix, Philippe, Lacut, Karine, Laffont, Joëlle-Yvette, Lambert, Marc, Chru, de Lille, Laroche, Jean-Pierre, Larrue, Vincent, Laskar, Marc, Laurian, Claude, Lazareth, Isabelle, Le Bras, Yann, Le Gal, Grégoire, Le Hello, Claire, Le Thi Huong, Du, Lecompte, Thomas, Leftheriotis, Georges, Lemarchand-Venencie, Françoise, Lemasle, Philippe, Letombe, Brigitte, Levesque, Hervé, Long, Anne, Luizy, François, Magnan, Pierre-Edouard, Magnant, Julie, Mallios, Alexandros, Marchand-Adam, Sylvain, Marie, Isabelle, Martinez, Carmen, Maumias, Thibault, Meaume, Sylvie, Messas, Emmanuel, Mestre, Sandrine, Meyer, Guy, Midy, Dominique, Mismetti, Patrick, Mollard, Jean-Marc, Montaudon, Michel, Moraglia, Luc, Mottier, Dominique, Mounier-Vehier, Claire, Moyou-Mogo, Roger, Nicolini, Philippe, Nourrissat, Ghislain, Ouvry, Pierre, Patra, Philippe, Perez Martin, Antonia, Pernes, Jean-Marc, Pernod, Gilles, Perret-Guillaume, Christine, Perrin, Michel, Pesteil, Francis, Pichot, Olivier, Pistorius, Marc-Antoine, Planchon, Bernard, Plouin, Pierre-François, Poggi, Jean-Noël, Priollet, Pascal, Quehe, Philippe, Quere, Isabelle, Ramelet, Albert-Adrien, Renaudin, Jean-Marc, Reny, Jean-Luc, Righini, Marc, Rosenbaum, David, Rosset, Eugenio, Roy, Pierre-Marie, Saadi, Leilah, Saby, Jean-Claude, Samama, Meyer Michel, Sandrin-Berthon, Brigitte, Satger-Gouin, Bernardette, Schuster-Beck, Iris, Chu, de Montpellier, Segard, Magali, Sene, Damien, Senet, Patricia, Serise, Jean Michel, Sessa, Carmine, Sevestre-Pietri, Marie-Antoinette, Sirvente, Jérôme, Solanilla, Anne, Soulier-Sotto, Virginie, Sprynger, Muriel, Stephan, Dominique, Sussman, Hélène, Tanguy, Bénédicte, Terriat, Béatrice, Thiebaugeorges, Olivier, Thomas, Daniel, Tribout, Laurent, Turpault, Jean-Philippe, Vaillant, Loïc, Van Cleef, Jean-François, Vayssairat, Michel, Vernhet-Kovasick, Hélène, Vicaut, Eric, Vignes, Stéphane, Villeneuve, Frédéric, Viremouneix, Loïc, Wahl, Denis, Warembourg, Frédérique, Wautrecht, Jean Claude, Wechsler, Bertrand, and Zuily, Stéphane

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44. [Dental caries as chronic disease, a new therapeutic approach].

Author

Trentesaux T, Sandrin-Berthon B, Stuckens C, Hamel O, and Hervé C

Subjects
Chronic Disease, Humans, Patient Education as Topic, Dental Caries therapy
Abstract

For many decades, oral health has been improving considerably in France. Caries indicators have decreased strongly. However, some "high risk" populations accumulate the majority of tooth decay. For them, health education and public health policies are inefficient. Tooth decay starts early and continues throughout their lives. Describing dental caries as a chronic pathology enables us to envisage alternative therapies, such as therapeutic patient education., (Copyright © 2010 Elsevier Masson SAS. All rights reserved.)

Published
2011
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45. [Adapted physical activity and patient education in the French diabetes networks].

Author

Perrin C, Champely S, Chantelat P, Berthon BS, Mollet E, Tabard N, and Tschudnowsky M

Subjects
Community Networks, France, Humans, Surveys and Questionnaires, Diabetes Mellitus therapy, Motor Activity, Patient Education as Topic
Abstract

A thorough questionnaire-based survey of French diabetes networks depicts an accurate description of the services they offer, in particular concerning physical activity. Often considered as less important than medicinal monitoring and dietetics, physical activity is at the core of a new professional dynamic. Practical sessions of adapted physical activity are presently offered in half the networks, as either one-time awareness-raising sessions or a complete series of sessions. Sports medicine educators seem to constitute an emerging professional group within a framework which aims to complement information provided to patients by skills-building through group sessions. Two distinct perspectives emerge as being linked to intervention methods: the first one aims to educate about physical activity, while the second aims to educate through physical activity.

Published
2008
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46. [Partnering with patients to reflect on the conceptual design of a therapeutic patient education programme].

Author

Sandrin Berthon B, Carpentier PH, Quéré I, and Satger B

Subjects
Family Practice, France, Hospitalists, Humans, Interviews as Topic, Nurses, Physical Therapy Specialty, Program Development, Surveys and Questionnaires, Intermittent Claudication therapy, Patient Education as Topic organization & administration, Patient Participation
Abstract

Within the framework of a patient education training programme, a group of health sector professionals comprised of hospital doctors, general practitioners, nurses, physiotherapists and dieticians created a programme intended for people with peripheral vascular disease (intermittent claudication). A study was carried out simultaneously utilising a questionnaire and a series of four interviews which permitted professionals to collect data on the patients' expectations regarding such a programme and their points of view at each specific stage of its development. This article analyses the contribution of the patients to the therapeutic patient education programme design, namely with respect to their influence on the programme's content, on the educational process and approach as well as on the professionals' perspectives on disease, various treatments and people with this particular illness. The discussion highlights the range of goals and objectives that can potentially be met through dialogue and exchange between people suffering from the same disease.

Published
2007
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