125 results on '"Berthelot, N."'
Search Results
2. A deeper look at the association between childhood maltreatment and reflective functioning
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Garon-Bissonnette, J., Dubois-Comtois, K., St-Laurent, D., Berthelot, N., Garon-Bissonnette, J., Dubois-Comtois, K., St-Laurent, D., and Berthelot, N.
- Abstract
Childhood maltreatment is theorized as impeding the development of reflective functioning (RF; ability to perceive and interpret oneself and others in terms of mental states). However, previous research typically failed to support this association or yielded small sized and mixed associations. This study aims to provide a deeper look at the association between childhood maltreatment and RF by characterizing two non-mentalizing categories. One-hundred-and-sixteen pregnant women (mean age = 27.62, SD = 4.52) from the community (48.3% with a university degree, 96.5% in a relationship with the other parent) retrospectively reported on childhood abuse and neglect using the Childhood Trauma Questionnaire. They also participated in the Adult Attachment Interview subsequently coded using the Reflective Functioning Scale. Participants with poor to low RF were allocated to one of two groups (disavowal-distancing or distorted-inconsistent) using indicators provided in the RF Scale. No association was found between childhood maltreatment and overall RF when controlling for education level. A multinomial logistic regression revealed that childhood maltreatment was strongly predictive of a disrupted, over-analytical and inconsistent reflection about mental states but not of a tendency to discourse little about mental states. This tendency was rather only predicted by education level. Findings suggest that childhood maltreatment would lead to specific impairments in RF and that not considering how individuals fail to mentalize about attachment relationships may mask strong associations between RF and its determinants and correlates, including childhood maltreatment.
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- 2023
3. STEP-COVID: A pilot study of a prenatal intervention for pregnant women during the COVID-19 pandemic
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Berthelot, N., Garon-Bissonnette, J., Drouin-Maziade, C., Bergeron, V., Sériès, T., Berthelot, N., Garon-Bissonnette, J., Drouin-Maziade, C., Bergeron, V., and Sériès, T.
- Abstract
The COVID-19 pandemic has been associated with a global increase in psychological distress in pregnant women. This study evaluated the effects of STEP-COVID, a six-session mentalization-based prenatal group program offered online during the COVID-19 pandemic. The 100 participants were allocated to STEP-COVID or to the natural trajectory of prenatal care. Pre- and post-intervention assessments included measures of psychological distress, post-traumatic symptoms and positive affectivity. Perception of change during pregnancy on resilience-promoting factors was also assessed at post-intervention. A significant decrease in psychological distress and post-traumatic symptoms and an increase in positive affectivity were observed in participants in the intervention condition, whereas only post-traumatic symptoms improved in the control condition. Women who participated in STEP-COVID also reported greater changes during pregnancy on resilience-promoting factors than women in the control condition. Results hold promise for buffering the effect of the pandemic on the mental health of pregnant women using brief online interventions. Clinical trial registration: NCT05419167 (15/06/2022)
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- 2023
4. Post-traumatic-stress in the context of childhood maltreatment: pathways from attachment through mentalizing during the transition to parenthood
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Ensink, K., Bégin, M., Martin-Gagnon, G., Biberdzic, M., Berthelot, N., Normandin, L., Fonagy, P., Bernazzani, O., Borelli, J. L., Ensink, K., Bégin, M., Martin-Gagnon, G., Biberdzic, M., Berthelot, N., Normandin, L., Fonagy, P., Bernazzani, O., and Borelli, J. L.
- Abstract
Introduction: This study aimed to clarify the role of mentalizing in pathways from attachment to Post Traumatic Stress Symptoms (PTSS) in survivors of childhood maltreatment (CM). We focused on the transition to parenting, a critical period for reworking parenting representations to reduce intergenerational maltreatment cycles. Method: Study participants included 100 pregnant CM survivors. We assessed PTSS with the SCID and attachment and mentalizing with the Adult Attachment Interview (AAI), which was rated for Attachment and Reflective Functioning (RF). Results: Regarding Re-experiencing trauma symptoms, the results of the path analysis were consistent with mediation. CM survivors' mentalizing about their early relationships with their parents (RF-Other) directly impacted Re-experiencing trauma symptoms, and attachment had an effect on Re-experiencing trauma symptoms through mentalizing (RF-Other). Regarding Arousal/Reactivity symptoms, the results of the pathways analysis were consistent with partial mediation by mentalizing about early relationships with parents (RF-Other). In addition to the pathway from attachment via mentalizing (RF-Other) to Arousal/Reactivity, the pathway between attachment and Arousal/Reactivity also remained significant. Discussion: This study provides new evidence of a mentalizing and attachment model of PTSS in CM survivors. The findings indicate that increased mentalizing about early relationships with parents is an important process associated with lower PTSS. Finally, we discuss the implications of developing interventions for CM survivors to reduce PTSS. Scaffolding the development of mentalizing regarding attachment relationships in which CM occurred may help CM survivors reduce the intrusion of traumatic memories and decrease trauma-related arousal and reactivity symptoms. Interventions to help CM survivors mentalize regarding parents and attachment relationships in which trauma occurred may be particularly important duri
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- 2023
5. Cumulative childhood trauma and complex psychiatric symptoms in pregnant women and expecting men
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Garon-Bissonnette, J., Grisé Bolduc, M.-È., Lemieux, R., Berthelot, N., Garon-Bissonnette, J., Grisé Bolduc, M.-È., Lemieux, R., and Berthelot, N.
- Abstract
Background: Women and men having been exposed to childhood trauma would be at high risk of various mental health symptoms while awaiting a child. This study aimed to evaluate the association between cumulative childhood trauma and the accumulation of symptoms belonging to different psychiatric problems in pregnant women and expecting men. Methods: We first examined prevalence rates of childhood trauma across our samples of 2853 pregnant women and 561 expecting men from the community. Second, we evaluated the association between cumulative childhood trauma and symptom complexity (i.e., the simultaneous presentation of symptoms belonging to multiple psychiatric problems) using subsamples of 1779 pregnant women and 118 expecting men. Participants completed self-reported measures of trauma (Childhood Trauma Questionnaire) and psychiatric symptoms (PTSD Checklist for DSM-5; Kessler Psychological Distress Scale; State-Trait Anger Expression Inventory-2; Self and Interpersonal Functioning Scale). Results: Trauma was more frequent in pregnant women than in expecting men and in participants reporting sociodemographic risk factors than in those not reporting any. A dose-response relationship was observed between the number of different traumas reported by pregnant women and expecting men and the complexity of their psychiatric symptoms, even when controlling for the variance explained by other risk factors. Women having been exposed to cumulative childhood trauma were 4.95 times more at risk of presenting comorbid psychiatric problems during pregnancy than non-exposed women. Conclusions: Childhood trauma is frequent in the general population of pregnant women and expecting men and is associated with symptom complexity during the antenatal period. These findings call for delivering and evaluating innovative trauma-informed antenatal programs to support mental health and adaptation to parenthood in adults having been exposed to childhood trauma. © 2021, The Author(s).
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- 2022
6. Childhood trauma may increase risk of psychosis and mood disorder in genetically high-risk children and adolescents by enhancing the accumulation of risk indicators
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Berthelot, N., Garon-Bissonnette, J., Jomphe, V., Doucet-Beaupré, H., Bureau, A., Maziade, M., Berthelot, N., Garon-Bissonnette, J., Jomphe, V., Doucet-Beaupré, H., Bureau, A., and Maziade, M.
- Abstract
Background: Genetically high-risk children carry indicators of brain dysfunctions that adult patients with schizophrenia or bipolar disorder display. The accumulation of risk indicators would have a higher predictive value of a later transition to psychosis or mood disorder than each individual risk indicator. Since more than 50% of adult patients report having been exposed to childhood trauma, we investigated whether exposure to trauma during childhood was associated with the early accumulation of risk indicators in youths at genetic risk. Methods: We first inspected the characteristics of childhood trauma in 200 young offspring (51% male) born to a parent affected by DSM-IV schizophrenia, bipolar disorder, or major depressive disorder. A subsample of 109 offspring (51% male) had measurements on four risk indicators: cognitive impairments, psychotic-like experiences, nonpsychotic nonmood childhood DSM diagnoses, poor global functioning. Trauma was assessed from direct interviews and reviews of lifetime medical and school records of offspring. Results: Trauma was present in 86 of the 200 offspring (43%). The relative risk of accumulating risk indicators in offspring exposed to trauma was 3.33 (95% CI 1.50, 7.36), but more pronounced in males (RR = 4.64, 95% CI 1.71, 12.6) than females (RR = 2.01, 95% CI 0.54, 7.58). Conclusion: Childhood trauma would be related to the accumulation of developmental precursors of major psychiatric disorders and more so in young boys at high genetic risk. Our findings may provide leads for interventions targeting the early mechanisms underlying the established relation between childhood trauma and adult psychiatric disorders.
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- 2022
7. Socioemotional development in infants of pregnant women during the COVID-19 pandemic : The role of prenatal and postnatal maternal distress
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Duguay, G., Garon-Bissonnette, J., Lemieux, R., Dubois-Comtois, K., Mayrand, K., Berthelot, N., Duguay, G., Garon-Bissonnette, J., Lemieux, R., Dubois-Comtois, K., Mayrand, K., and Berthelot, N.
- Abstract
Background An upsurge in psychological distress was documented in pregnant women during the COVID-19 pandemic. We investigated with a longitudinal design whether prenatal and postnatal maternal distress during the COVID-19 pandemic was associated with lower infant socioemotional development. Methods Pregnant women (N = 468, Mage = 30,00, 97.6% White) were recruited during the first COVID-19 mandatory lockdown in Quebec, Canada, from April 2nd to April 13th 2020 and were re-contacted at two months postpartum to complete self-reported measures of general (i.e. not specifically related to the COVID-19 pandemic) anxio-depressive symptoms and infant development. Structural equation modeling analyses were performed using maximum likelihood parameter estimation. Results Higher maternal prenatal distress significantly contributed to poorer infant socioemotional development. A mediation model showed that postnatal distress significantly mediated the association between prenatal distress and infant socioemotional development, whereas the direct effect of prenatal distress was no longer significant. Prenatal and postnatal maternal distress accounted for 13.7% of the variance in infant socioemotional development. Conclusion Our results call for special means of clinical surveillance in mothers and for innovative (online) interventions aiming to support maternal mental health during pregnancy and after delivery.
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- 2022
8. Une intervention de groupe brève pour favoriser le bien-être des femmes enceintes pendant la pandémie de COVID-19 et soutenir la résilience des familles
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Berthelot, N., Drouin-Maziade, C., Bergeron, V., Garon-Bissonnette, J., Sériès, T., Berthelot, N., Drouin-Maziade, C., Bergeron, V., Garon-Bissonnette, J., and Sériès, T.
- Abstract
Contexte: La pandémie de COVID-19 a été associée à une augmentation de la détresse psychologique chez les femmes enceintes. Le présent article vise à évaluer l’acceptabilité du programme STEP-COVID (Soutenir la Transition et l’Engagement dans la Parentalité dans le contexte de la pandémie de COVID-19), une intervention prénatale de groupe en ligne, en mode synchrone, visant à soutenir le bien-être, la mentalisation et la résilience. Méthode: Vingt et une femmes enceintes québécoises ont participé au programme et ont complété des mesures des symptômes psychologiques et de la mentalisation avant et après l’intervention ainsi qu’une échelle évaluant leur perception de changements sur des domaines associés à la résilience. Après chaque rencontre, elles ont rempli un questionnaire évaluant leur appréciation du programme. Résultats: Les 18 participantes (86 %) ayant complété le programme ont rapporté de hauts taux de satisfaction après chacune des rencontres et au terme de l’intervention. Une diminution des symptômes anxio-dépressifs et des symptômes de stress post-traumatiques et une amélioration des fonctions réflexives sont observées entre le début et la fin du programme. Les participantes ont également rapporté des changements positifs sur des sphères de fonctionnement associées à la résilience. Conclusion: Les résultats soutiennent l’acceptabilité du programme STEP-COVID et suggèrent que l’offre d’une intervention de groupe brève en ligne est appréciée par les participantes, semble favoriser une diminution de la détresse psychologique et une amélioration de la mentalisation et pourrait contribuer à la résilience dans le contexte de la pandémie de COVID-19.
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- 2022
9. L’expérience des participantes au programme STEP : une intervention prénatale pour les femmes ayant subi de mauvais traitements durant leur enfance
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Berthelot, N., Goupil, É., Drouin-Maziade, C., Lacharité, C., Lemieux, R., Garon-Bissonnette, J., Berthelot, N., Goupil, É., Drouin-Maziade, C., Lacharité, C., Lemieux, R., and Garon-Bissonnette, J.
- Abstract
Résumé Contexte : Le programme STEP est une intervention prénatale de groupe destinée aux femmes enceintes ayant vécu des traumatismes interpersonnels au cours de leur enfance tels que la maltraitance. La présente étude vise à décrire l’expérience des participantes de leur participation au programme. Méthodologie : Des entretiens individuels ont été réalisés auprès de 21 participantes ayant complété le programme afin de sonder leur appréciation de l’intervention, l’adéquation entre le contenu et leurs attentes, les points forts et les points faibles, la sensibilité à leur réalité personnelle, familiale et culturelle ainsi que l’importance qu’elles attribuent aux différents thèmes abordés. Résultats : Les participantes se représentent le programme STEP comme une occasion unique d’exploration de soi à titre d’individu et de mère et considèrent que le programme favorise un sentiment subjectif de mieux-être. Trois dimensions ont été identifiées au coeur de cette expérience : (1) le contenu du programme est perçu comme étant sensible, équilibré, concret et progressif, (2) le collectif/entre-mères favorise la socialisation de la maternité, la prise de recul, les échanges et la validation de soi et (3) le cadre d’animation sécurisant est perçu par le biais de la bienveillance de l’équipe d’animation, sa compétence, sa cohésion et la réciprocité dont elle fait preuve dans sa relation avec les participantes. Discussion : Les résultats soutiennent que les femmes enceintes ayant vécu une forme de traumatisme interpersonnel perçoivent que le programme STEP répond à leurs besoins et que ses composantes favorisent une expérience plus profonde et sereine de leur grossesse ainsi qu’une meilleure disposition à accueillir leur enfant. Abstract Background: The STEP program is a prenatal group intervention for pregnant women who experienced childhood interpersonal traumas such as child abuse or neglect. The study aims to document participants’ experience of their participation in the p
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- 2022
10. Impact of parental cannabis
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Patel, Vinood B., Preedy, Victor R., Berthelot, N., Morneau, M., Lacharité, C., Patel, Vinood B., Preedy, Victor R., Berthelot, N., Morneau, M., and Lacharité, C.
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This chapter aims to review the current knowledge about the effects of parental cannabis use on parenting behaviors and offspring development and to discuss the covering of the issue of parental cannabis use by mass media and public health organizations. Existing research has generally concluded that parental cannabis use is a significant risk factor for parenting and child development. However, there is still a paucity of empirical studies on this topic, and existing research presents important limitations, restraining our ability to conclude about the dangers of using cannabis when caring for a child. At this point, very little is known about the circumstances under which the use of cannabis is a risk factor for parenting and about the mechanisms through which parental cannabis use influences offspring development. The lack of hard facts addressing these issues allows for mass media to promote opinion-based publications that praise the parental use of cannabis.
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- 2022
11. Inverted Repeat Nucleotide Sequences in the Genomes of Marek Disease Virus and the Herpesvirus of the Turkey
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Cebrian, J., Kaschka-Dierich, C., Berthelot, N., and Sheldrick, P.
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- 1982
12. OPEN RADIATION: a collaborative project for radioactivity measurement in the environment by the public
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Bottollier-Depois Jean-François, Allain E., Baumont G., Berthelot N., Clairand I., Couvez C., Darley G., Henry B., Jolivet T., Laroche P., Lebau-Livé A., Lejeune V., Miss J., Monange W., Quéinnec F., Richet Y., Simon C., Trompier F., and Vayron F.
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Physics ,QC1-999 - Abstract
After the Fukushima accident, initiatives emerged from the public to carry out themselves measurements of the radioactivity in the environment with various devices, among which smartphones, and to share data and experiences through collaborative tools and social networks. Such measurements have two major interests, on the one hand, to enable each individual of the public to assess his own risk regarding the radioactivity and, on the other hand, to provide “real time” data from the field at various locations, especially in the early phase of an emergency situation, which could be very useful for the emergency management. The objective of the OPENRADIATION project is to offer to the public the opportunity to be an actor for measurements of the radioactivity in the environment using connected dosimetric applications on smartphones. The challenge is to operate such a system on a sustainable basis in peaceful time and be useful in case of emergency. In “peaceful situation”, this project is based on a collaborative approach with the aim to get complementary data to the existing ones, to consolidate the radiation background, to generate alerts in case of problem and to provide education & training and enhanced pedagogical approaches for a clear understanding of measures for the public. In case of emergency situation, data will be available “spontaneously” from the field in “real time” providing an opportunity for the emergency management and the communication with the public. … The practical objective is i) to develop a website centralising data from various systems/dosimeters, providing dose maps with raw and filtered data and creating dedicated areas for specific initiatives and exchanges of data and ii) to develop a data acquisition protocol and a dosimetric application using a connected dosimeter with a bluetooth connection. This project is conducted within a partnership between organisms’ representative of the scientific community and associations to create links with the public.
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- 2017
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13. Evaluation of the acceptability of a prenatal program for women with histories of childhood trauma: The program STEP
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Berthelot, N., Drouin-Maziade, C., Garon-Bissonnette, J., Lemieux, R., Sériès, T., Lacharité, C., Berthelot, N., Drouin-Maziade, C., Garon-Bissonnette, J., Lemieux, R., Sériès, T., and Lacharité, C.
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Background: Childhood trauma would negatively affect pregnant women's mental health and would have intergenerational repercussions. However, there is a paucity of prenatal interventions specifically designed for women exposed to childhood trauma. The study aims to evaluate the acceptability of STEP, a manualized group intervention designed for pregnant women having experienced early life adversity. Methods: The acceptability of STEP was assessed in four phases. In Phase 1, six experts evaluated whether the program activities were pertinent and trauma sensitive. In Phase 2, three parents read the intervention manuals and evaluated whether they considered each session relevant, interesting, and clear. In Phase 3, the program was briefly presented by phone to 309 pregnant women from the community. Women were inquired about their interest in the program, and the reasons for their lack of interest were assessed. In Phase 4, 30 pregnant women exposed to childhood trauma participated in the program and completed anonymous satisfaction questionnaires after each session. Psychological distress was also measured before and after the program. Results: All activities were rated by independent experts as highly pertinent, adequate, and sufficiently safe to be offered to pregnant women. Parents who read through the intervention manuals also considered that the sessions were relevant, clear, and interesting. About half of the pregnant women from the community showed interest in the program. Participants reported very high levels of satisfaction and a significant decrease in psychological distress during the program. Conclusions: Our findings show a high level of convergence among various indicators of program acceptability.
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- 2021
14. Maternal childhood abuse and neglect predicts offspring development in early childhood: the roles of reflective functioning and child sex
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Garon-Bissonnette, J., Duguay, G., Lemieux, R., Dubois-Comtois, K., Berthelot, N., Garon-Bissonnette, J., Duguay, G., Lemieux, R., Dubois-Comtois, K., and Berthelot, N.
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Background: Recent evidence suggests that offspring of mothers having been exposed to childhood abuse and neglect (CA&N) are at increased risk of developmental problems and that boys are more affected by maternal CA&N than girls. Since impairments in reflective functioning (RF) have been associated with maternal CA&N and offspring development, RF could represent a key mechanism in these intergenerational risk trajectories. Objective: This study evaluated mediating (RF) and moderating (child sex) mechanisms in the association between maternal CA&N and child development. Participants and setting: In a longitudinal setting, 111 mothers completed measures during pregnancy and between 11 and 36 months postpartum. Methods: CA&N and impairments in RF were assessed during pregnancy and offspring development was measured during the longitudinal follow-up using the Ages and Stages Questionnaires (ASQ-3). Child development was operationalized in two ways: using the global score at the ASQ-3 and using a dichotomous score of accumulation of delays across domains of development. Results: Structural equation modeling indicated that RF mediated the association between maternal CA&N and offspring development. Child sex moderated the association between CA&N and the clustering of developmental problems (Wald = 5.88, p = 0.02), with boys being particularly likely to accumulate developmental delays when their mother experienced CA&N (RR = 2.62). Accumulation of developmental problems was associated with impairments in maternal RF in girls and with maternal exposure to CA&N in boys. Conclusions: Results provide novel insights on the role of mentalization and child sex in the association between maternal CA&N and child development. © 2021 The Authors
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- 2021
15. Development and validation of a self-report measure assessing failures in the mentalization of trauma and adverse relationships
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Berthelot, N., Savard, C., Lemieux, R., Garon-Bissonnette, J., Ensink, K., Godbout, N., Berthelot, N., Savard, C., Lemieux, R., Garon-Bissonnette, J., Ensink, K., and Godbout, N.
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Background: The way people process trauma and adverse relationships may be more predictive of subsequent adaptation than trauma exposure in itself. However, there is currently no self-report instrument assessing failures in the mentalization of trauma and adverse relationships. Objective: We developed the Failure to Mentalize Trauma Questionnaire (FMTQ) and evaluated its psychometric properties. The FMTQ is a 29-item self-report instrument designed to assess different indications of failures in the mentalization of trauma and adverse relationships. Participants and setting A total of 975 participants (84 % women; 37 % exposed to child maltreatment) were recruited in the course of larger research protocols on parenting. Methods: Participants completed the FMTQ and measures of childhood maltreatment, psychopathology (post-traumatic stress symptoms, dissociative symptoms, level of personality dysfunction), general mentalization and intimate partner violence. Results: Exploratory factor analysis, supported by a confirmatory factor analysis, identified seven factors with good internal consistency that corresponded to different types of failures in the mentalization of trauma and adverse relationships and that loaded on a general factor. A dose-effect association was observed between the severity of childhood maltreatment, and the severity of failures in the mentalization of trauma and adverse relationships (rs = .49, p < .01). The FMTQ total score explained a significant proportion of variance in psychopathology and intimate partner violence, both in participants with histories of childhood maltreatment and participants without childhood maltreatment. Conclusion: The FMTQ is a promising, concise and efficient measure of failures in the mentalization of trauma and adverse relationships that may facilitate clinical screening and research with adults who experienced trauma.
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- 2021
16. Impact of level of personality pathology on affective, behavioral, and thought problems in pregnant women during the Coronavirus Disease 2019 pandemic
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Gamache, D., Savard, C., Lemieux, R., Berthelot, N., Gamache, D., Savard, C., Lemieux, R., and Berthelot, N.
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Among at-risk groups for psychological distress in the context of the Coronavirus Disease 2019 (COVID-19) pandemic, pregnant women might be especially vulnerable. Identifying subgroups of pregnant women at high risk of poor adaptation might optimize clinical screening and intervention, which could, in turn, contribute to mitigating the potentially devastating effects of prenatal stress on mothers and fetus. Level of personality functioning may be a good indicator of who may be more vulnerable to distress in challenging periods like the COVID-19 pandemic, as adults with high levels of personality dysfunction may experience significant difficulties in mentalizing threatening situations. The aims of the present study are (a) to determine the impact of level of personality pathology on affective, behavioral, and thought problems in pregnant women during the COVID-19 pandemic; and (b) to test a model where mentalization of trauma mediates the impact of personality pathology on symptomatology. Data from 1,207 French-Canadian pregnant women recruited through social media during the COVID-19 pandemic were analyzed. Latent profile analysis, using the Criterion A elements of the alternative model for personality disorders (Identity, Self-Direction, Empathy, Intimacy) as latent indicators, yielded four profiles: Healthy, Mild Self-Impairment, Intimacy Impairment, and Personality Disorder. Profiles showed significant associations with diverse indicators of symptomatology. Mediation models showed both direct and indirect (through mentalization of trauma) significant associations between level of personality functioning and affective/behavioral/thought problems. Results have clinical implications on prophylactic measures for at-risk pregnant women, especially in challenging contexts such as the COVID-19 pandemic.
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- 2021
17. A Proposed Classification of ICD-11 Severity Degrees of Personality Pathology Using the Self and Interpersonal Functioning Scale
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Gamache, D., Savard, C., Leclerc, P., Payant, M., Berthelot, N., Côté, A., Faucher, J., Lampron, M., Lemieux, R., Mayrand, K., Nolin, M.-C., Tremblay, M., Gamache, D., Savard, C., Leclerc, P., Payant, M., Berthelot, N., Côté, A., Faucher, J., Lampron, M., Lemieux, R., Mayrand, K., Nolin, M.-C., and Tremblay, M.
- Abstract
Background: The 11th version of the World Health Organization's International Classification of Diseases (ICD-11) has adopted a dimensional approach to personality disorder (PD) nosology. Notably, it includes an assessment of PD degree of severity, which can be classified according to five categories. To date, there is no gold standard measure for assessing degree of PD severity based on the ICD-11 model, and there are no empirically-based anchor points to delineate the proposed categories. With the operationalization of PD degrees of severity in the ICD-11 PD model now being closely aligned with Criterion A of the DSM-5 Alternative Model for Personality Disorders (AMPD), sharing a focus on self and interpersonal dysfunction, self-report instruments developed for the latter model might prove useful as screening tools to determine degrees of severity in the former.Methods: The Self and Interpersonal Functioning Scale, a brief validated self-report questionnaire originally designed to assess level of personality pathology according to the AMPD framework, was used to derive anchor points to delineate the five severity degrees from the ICD-11 PD model. Data from five clinical and non-clinical samples (total N = 2,240) allowed identifying anchor points for classification, based on Receiver Operating Characteristic curve analysis, Latent Class Analysis, and data distribution statistics. Categories were validated using multiple indices pertaining to externalizing and internalizing symptoms relevant to PD.Results: Analyses yielded the following anchor points for PD degrees of severity: No PD = 0–1.04; Personality Difficulty = 1.05–1.29; Mild PD = 1.30–1.89; Moderate PD = 1.90–2.49; and Severe PD = 2.50 and above. A clear gradient of severity across the five categories was observed in all samples. A high number of significant contrasts among PD categories were also observed on external variables, consistent with the ICD-11 PD degree of severity operationalization.Conclusions
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- 2021
18. Uptrend in Distress and Psychiatric Symptomatology in Pregnant Women During the Coronavirus Disease 2019 Pandemic
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Berthelot, N., primary, Lemieux, R., additional, Garon-Bissonnette, J., additional, Drouin-Maziade, C., additional, Martel, É., additional, and Maziade, M., additional
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- 2021
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19. 0859 Types Of Childhood Maltreatment And Sleep Regulation During Pregnancy
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Touchette, E, primary, Servot, S, primary, Lemieux, R, primary, and Berthelot, N, primary
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- 2020
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20. The OpenRadiation project: monitoring radioactivity in the environment by and for the citizens
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Bottollier-Depois, J.F., primary, Allain, E., additional, Baumont, G., additional, Berthelot, N., additional, Darley, G., additional, Ecrabet, F., additional, Jolivet, T., additional, Lebeau-Livé, A., additional, Lejeune, V., additional, Quéinnec, F., additional, Simon, C., additional, and Trompier, F., additional
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- 2019
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21. The Mirror Paradigm: Assessing the Embodied Self in the Context of Abuse
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Ensink, Karin, Berthelot, N, Biberdzic, Marko, Normandin, Lina, Ensink, Karin, Berthelot, N, Biberdzic, Marko, and Normandin, Lina
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- 2016
22. OPEN RADIATION: a collaborative project for radioactivity measurement in the environment by the public.
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Henry, B., Bottollier-Depois, Jean-François, Baumont, G., Clairand, I., Couvez, C., Darley, G., Lebau-Livé, A., Lejeune, V., Monange, W., Quéinnec, F., Richet, Y., Trompier, F., Vayron, F., Allain, E., Berthelot, N., Jolivet, T., Laroche, P., and Simon, C.
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RADIOACTIVITY safety measures ,RADIOACTIVITY & the environment ,RADIATION dosimetry ,RADIATION ,FUKUSHIMA Nuclear Accident, Fukushima, Japan, 2011 ,GOVERNMENT policy - Abstract
After the Fukushima accident, initiatives emerged from the public to carry out themselves measurements of the radioactivity in the environment with various devices, among which smartphones, and to share data and experiences through collaborative tools and social networks. Such measurements have two major interests, on the one hand, to enable each individual of the public to assess his own risk regarding the radioactivity and, on the other hand, to provide "real time" data from the field at various locations, especially in the early phase of an emergency situation, which could be very useful for the emergency management. [ABSTRACT FROM AUTHOR]
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- 2017
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23. Procédé et installation de traitement sélectif des gaz dans un mélange gazeux
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Duran, E., Berthelot, N., Favre, Eric, Lapicque, François, Bonnet, Caroline, Carré, Patrick, Laboratoire Réactions et Génie des Procédés (LRGP), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), and Wild, Gabriel
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[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process Engineering ,[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process Engineering - Published
- 2010
24. Beyond the reflection – the role of the mirror paradigm
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Normandin, L., primary, Ensink, K., additional, and Berthelot, N., additional
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- 2012
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25. Mother-Infant attachment, reflective functioning, and unresolved trauma in mothers with childhood histories of abuse and neglect: A prospective study
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Ensink, K., primary, Berthelot, N., additional, Bernazzani, O., additional, Normandin, L., additional, and Luyten, P., additional
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- 2012
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26. Delayed decontamination effectiveness following skin exposure to the chemical warfare agent VX
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Josse, D., primary, Barrier, G., additional, Cruz, C., additional, Ferrante, M.C., additional, and Berthelot, N., additional
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- 2011
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27. Formation of Chlorination By-Products in Sanitary Hot Water Networks Treated by Continuous Chlorination
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Berthelot, N., primary, Personnaz, V., additional, Benanou, D., additional, Oberti, S., additional, Bouteleux, C., additional, and Recherche, Anjou, additional
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- 2009
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28. Occurrence des amibes libres en réseaux d’eau intérieurs
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Ménard-Szczebara, F., primary, Berthelot, N., additional, Cavereau, D., additional, Oberti, S., additional, Héchard, Y., additional, Sarroca, V., additional, Rivière, D., additional, and Mazoua, S., additional
- Published
- 2008
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29. Concurrent-error detection in high-speed carry-free dividers
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Wey, C.-L., primary, Berthelot, N., additional, and Veltkamp, B., additional
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- 1994
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30. Ecology of free-amoebae in real in-house water networks
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M?nard-Szczebara, F., Berthelot, N., Cavereau, D., Oberti, S., H?chard, Y., Sarroca, V., Rivi?re, D., and Mazoua, S.
- Abstract
Free amoebae are protozoa largely encountered in environmental and hydric niches. They have the ability to multiply without the help of any host. A few species are direct human pathogens (Naegleria fowleri?) and a lot of them can be reservoirs for pathogenic bacteria like Legionella pneumophila. To evaluate the occurrence and the characteristics of free living amoebae in in-house water networks, an analytical campaign was realized in real distribution systems (cold and hot water). Thirty six sites were tested for the presence of amoebae (five sampling points for hot and cold water). Total amoebae were quantified by the method (MPN) described by Pernin et al. Identification was made by microscopic morphology determination. In French in-house networks, the most representative amoebal genus is Hartmanella. In several samples, Acanthamoeba was also isolated. Among installation network parameters (temperature, pipe material, presence of loops, type of hot water production), temperature (up to 60?C) seems to be the preponderant parameter controlling the presence of amoebae.Les amibes libres sont des protozoaires (unicellulaires) tr?s pr?sents dans l?environnement et notamment dans les milieux hydriques et ont la capacit? ? s?y multiplier sans l?aide d?un h?te. Certaines esp?ces sont directement pathog?nes pour l?homme mais d?autres peuvent ?galement ?tre responsables, de fa?on indirecte, d?infections en jouant le r?le de r?servoir de bact?ries pathog?nes comme Legionella pneumophila. Afin d??valuer l?occurrence des amibes libres en eau chaude sanitaire, une campagne d?analyse a ?t? r?alis?e sur 36 r?seaux int?rieurs r?els (eau froide et eau chaude). La campagne d?analyse sur sites a montr? que les amibes libres thermophiles sont retrouv?es dans 19 % des pr?l?vements effectu?s et les amibes m?sophiles dans 46 %. Le genre amibien le plus retrouv? est Hartmanella. A priori, ce genre d?amibe n?est pas intrins?quement pathog?ne pour l?homme. Sur quelques ?chantillons, des amibes du genre Acanthamoeba ont ?t? retrouv?es. Les points les plus fr?quemment contamin?s par les amibes libres sont l?eau froide et les points d?usage. Les caract?ristiques des sites ont ?t? mis au regard de la contamination par les amibes totales. Aucune corr?lation n?a pu ?tre trouv?e entre la pr?sence d?amibes et le type d??tablissement, le type de production d?eau chaude, la qualit? du bouclage, le type de mat?riaux. Tr?s peu d?amibes sont retrouv?es lorsque la temp?rature de l?eau est sup?rieure ? 60 ?C.
- Published
- 2008
31. Physical mapping and nucleotide sequence of a herpes simplex virus type 1 gene required for capsid assembly
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Pertuiset, B, Boccara, M, Cebrian, J, Berthelot, N, Chousterman, S, Puvion-Dutilleul, F, Sisman, J, and Sheldrick, P
- Abstract
In this report, we describe some phenotypic properties of a temperature-sensitive mutant of herpes simplex type 1 (HSV-1) and present data concerning the physical location and nucleotide sequence of the genomic region harboring the mutation. The effect of shifts from the permissive to the nonpermissive temperature on infectious virus production by the mutant A44ts2 indicated that the mutated function is necessary throughout, or late in, the growth cycle. At the nonpermissive temperature, no major differences were detected in viral DNA or protein synthesis with respect to the parent A44ts+. On the other hand, electron microscopy of mutant-infected cells revealed that neither viral capsids nor capsid-related structures were assembled at the nonpermissive temperature. Additional analyses employing the Hirt extraction procedure showed that A44ts2 is also unable to mature replicated viral DNA into unit-length molecules under nonpermissive conditions. The results of marker rescue experiments with intact A44ts2 DNA and cloned restriction fragments of A44ts+ placed the lesion in the coordinate interval 0.553 to 0.565 (1,837 base pairs in region UL) of the HSV-1 physical map. No function has previously been assigned to this region, although it is known to be transcribed into two 5' coterminal mRNAs which code in vitro for a 54,000-molecular-weight polypeptide (K. P. Anderson, R. J. Frink, G. B. Devi, B. H. Gaylord, R. H. Costa, and E. K. Wagner, J. Virol. 37:1011-1027, 1981). We sequenced the interval 0.551 to 0.565 and found an open reading frame (ORF) for a 50,175-molecular-weight polypeptide. The predicted product of this ORF exhibits strong homology with the product of varicella-zoster virus ORF20 and lower, but significant, homology with the product of Epstein-Barr virus BORF1. For the three viruses, the corresponding ORFs lie just upstream of the gene coding for the large subunit of viral ribonucleotide reductase. The ORF described here corresponds to the ORF designated UL38 in the recently published nucleotide sequence of the HSV-1 UL region (D. J. McGeoch, M. A. Dalrymple, A. J. Davison, A. Dolan, M. C. Frame, D. McNab, L. J. Perry, J. E. Scott, and P. Taylor, J. Gen. Virol. 69:1531-1574, 1988).
- Published
- 1989
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32. Genome structure of cottontail rabbit herpesvirus
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Cebrian, J, Berthelot, N, and Laithier, M
- Abstract
The genome structure of a herpesvirus isolated from primary cultures of kidney cells from the cottontail rabbit Sylvilagus floridanus was elucidated by using electron microscopy and restriction enzyme analysis. The genome, which was about 150 kilobase pairs long and which had an average G + C composition of 45%, consisted of two regions with unique base sequences (54 and 47 kilobase pairs) enclosed by reiterations of a 925-base-pair sequence with a variable copy number. The internal repeats were in opposite polarity with respect to the terminal repeats, and both unique regions underwent inversion. The nucleotide sequence of the repeat unit was determined, and virion DNA termini were precisely localized within this sequence. Elements showing homology with the cleavage-packaging signals common to other herpesviruses were detected. The data indicate that this virus is different from the previously described herpesvirus sylvilagus.
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- 1989
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33. Genome structure and virion polypeptides of the primate herpesviruses Herpesvirus aotus types 1 and 3: comparison with human cytomegalovirus
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Ebeling, A, Keil, G, Nowak, B, Fleckenstein, B, Berthelot, N, and Sheldrick, P
- Abstract
Two serologically distinguishable primate herpesviruses, Herpesvirus aotus type 1 and type 3, were examined with regard to their genomes and structural polypeptides. The duplex DNA genomes of these two viruses were found to be essentially identical in molecular weight (Mr approximately equal to 145 X 10(6)) and guanine plus cytosine composition (55%). Both contained unique and inverted repeat nucleotide sequences of the same size and arrangement, which, as judged by DNA-DNA hybridization and restriction enzyme analyses, were at least 95% homologous. In addition, no differences were observed in electrophoretic profiles of virion polypeptides. Because of their great similarity with respect to these criteria, the two viruses ought to be considered independent isolates (or strains) of a single virus, which should be designated H. aotus type 1. The elevated molecular weight and presence of two sets of inverted repeat sequences closely resemble the structure of the human cytomegalovirus genome. However, no sequence homology (less than 5%) nor similarity in virion polypeptides was detected between H. aotus type 1 and human cytomegalovirus.
- Published
- 1983
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34. Sur quelques facteurs influençant la teneur en phosphore et calcium des poils d'une population de vaches normandes au cours d'un an. Relations avec l'aptitude laitière (Note présentée par M. Letard)
- Author
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Brochart, M.,, Coléou, J.,, Larvor, P.,, Berthelot, N.,, Salaün, M.,, ProdInra, Migration, Unité de Recherche d'Épidémiologie Animale (UR EpiA), and Institut National de la Recherche Agronomique (INRA)
- Subjects
[SDV] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] - Published
- 1959
35. Inverted Repetitions in the Chromosome of Herpes Simplex Virus
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Sheldrick, P., primary and Berthelot, N., additional
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- 1974
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36. Accommodating Former Legal Systems and Roman Law : Cicero’s Rhetorical and Legal Viewpoint in the Verrine Orations
- Author
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Dubouloz, Julien, Centre Camille Jullian - Histoire et archéologie de la Méditerranée et de l'Afrique du Nord de la protohistoire à la fin de l'Antiquité (CCJ), Aix Marseille Université (AMU)-Ministère de la Culture et de la Communication (MCC)-Centre National de la Recherche Scientifique (CNRS), K. Berthelot, N. Dohrmann & C. Nemo-Pekelman, K. Berthelot, N. Dohrmann, C. Nemo-Pekelman, and Dubouloz, Julien
- Subjects
Hiero II of Syracuse ,[SHS.HIST] Humanities and Social Sciences/History ,Roman tax system ,Roman imperialism ,Verrine orations ,Roman vs. local law ,uadimonium promittere ,Cicero ,[SHS.HIST]Humanities and Social Sciences/History ,Sicily ,Lex Rupilia ,first century BCE ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience; This paper considers the legal relations between local communities and Roman authorities within the empire from a Roman point of view. It is mostly based on Cicero’s Verrine Orations, the accusation pronounced in 70 BCE before a repetundae court against Verres, a former governor of Sicily. This piece of judicial rhetoric gives us access to the kind of arguments which were suitable for a Roman audience and Roman readers as far as provincial autonomy was concerned. A study of a specific civil law procedure, the uadimonium procedure, shows how difficult it is to assess the degree of interaction between local and Roman law from a judicial source like the Verrines. Furthermore, local law appears to be, to a large extent, both a rhetorical and an ethical construct, to be interpreted in the context of the critical viewpoint on imperialism which was cautiously developed by Cicero as the accuser in the repetundae speech.
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- 2018
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37. Using the DRS-8 to measure unresolved/disorganized attachment: Associations with states of mind on the adult attachment interview, psychopathology, and offspring social-emotional development.
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Mayrand K, Milot T, Briere J, Godbout N, Oliva-Veilleux S, and Berthelot N
- Subjects
- Humans, Female, Adult, Male, Infant, Reproducibility of Results, Pregnancy, Surveys and Questionnaires standards, Young Adult, Psychometrics, Interview, Psychological methods, Child Development, Object Attachment
- Abstract
Background: Unresolved/disorganized (U/d) attachment states of mind are associated with poor outcomes across numerous domains of functioning. However, the validity of existing self-report instruments measuring this construct remains questionable., Objectives: The aim of the current study was to validate the DRS-8, an alternative version of the Disorganized Response Scale (DRS), by assessing its construct validity, internal consistency, and criterion validity with the U/d attachment scales on the Adult Attachment Interview (AAI)., Participants and Setting: Date were collected from 222 expectant parents (78 % women) at T1 and from 67 of them at 12 months postpartum (T2)., Methods: Participants completed the DRS-8 and questionnaires assessing childhood trauma, romantic attachment, and psychological symptoms during pregnancy (T1). Seventy-four of them participated in the AAI at T1. At T2, parents completed a questionnaire assessing their infants' social-emotional development., Results: The DRS-8 has two highly correlated dimensions, i.e., lapses in the monitoring of reasoning (four items) and discourse (four items). A confirmatory factor analysis supported a bifactor structure of the instrument, showing good fit indices and internal consistency (ω = 0.87). The DRS-8 was significantly correlated with U/d states of mind on the AAI, r(72) = 0.28, p = .016, and demonstrated excellent construct validity. Significant indirect effects of the DRS-8 were found in the associations between childhood trauma and psychological symptoms, and between parental trauma and infant social-emotional development., Conclusions: The DRS-8 appears to be a promising self-report measure of U/d states of mind showing criterion validity with the AAI., Competing Interests: Declaration of competing interest None., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2024
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38. Resolving trauma: The unique contribution of trauma-specific mentalization to maternal insightfulness.
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Berthelot N, Garon-Bissonnette J, Muzik M, Simon V, Menke R, Stacks AM, and Rosenblum KL
- Abstract
Resolving trauma may contribute to mental health and parenting in mother with histories of childhood maltreatment. The concept of trauma-specific reflective functioning (T-RF) was developed to assess the complexity of thought processes regarding trauma. The study aimed to validate the T-RF scale applied to the Trauma Meaning-Making Interview by examining its psychometric properties, associations with measures of trauma-processing strategies, maternal reflective functioning and mental health (depression and post-traumatic stress disorder [PTSD]), as well as evaluating whether T-RF offered a unique contribution to maternal insightfulness. Good construct validity of the T-RF scale was confirmed in a sample of 112 mothers with histories of childhood maltreatment using an independent coding system of trauma-processing. Better mentalization of trauma was prospectively associated with higher parental reflective functioning and mothers with high T-RF were much more likely to be insightful regarding the child's mental states than non-reflective mothers and mothers with limited T-RF. The association between T-RF and insightfulness was observed even when controlling for maternal reflective functioning, trauma-processing strategies, maternal education and sociodemographic risk. T-RF was associated neither with depression, PTSD nor the characteristics of trauma. Findings suggest that mentalizing trauma would be an important protective factor in the intergenerational trajectories of trauma.
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- 2024
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39. Characterizing the heterogeneity of disruptions in the resolution of trauma among women exposed to childhood maltreatment.
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Berthelot N and Garon-Bissonnette J
- Abstract
The previously observed heterogeneity in developmental and intergenerational trajectories of childhood trauma may root from interindividual differences in the way trauma-exposed individuals have resolved these experiences. The current study explored whether distinctive patterns of impaired mentalization in relation to trauma could be identified in a sample of 825 pregnant women who experienced childhood maltreatment and whether these heterogeneous patterns were marked by significant differences in internalized and externalized problems during pregnancy, intimate partner violence, personality dysfunctions, and antenatal attachment. A latent profile analysis applied to the seven subscales of the Failure to Mentalize Trauma Questionnaire unraveled interindividual variability in mentalizing impairments among pregnant women exposed to childhood maltreatment by identifying five distinctive types of psychological responses to trauma, each being associated in cross-sectional analyses with a specific set of symptoms and dysfunctions. Overall, the study highlights the need for tailored interventions based on the individuals' specific impairments in mentalizing trauma and calls for future developmental research exploring the longitudinal correlates of the five documented profiles of trauma processing.
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- 2024
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40. Spillover effects on the relationship with the partner of a mentalization-based intervention for pregnant women.
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Berthelot N, Larouche K, Garon-Bissonnette J, Deschênes K, Drouin-Maziade C, and Lemieux R
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- Humans, Female, Pregnancy, Adult, Interpersonal Relations, Male, Quebec, Personal Satisfaction, Spouses psychology, Qualitative Research, Parenting psychology, Young Adult, Pregnant People psychology, Mentalization
- Abstract
The birth of a child has been associated with a decline in couple satisfaction, which has implications for the child's social-emotional development. This study investigated the potential spillover effect on pregnant women's perceptions of their relationships with their partners of the Supporting the Transition to and Engagement in Parenthood (STEP) program, a brief trauma-informed mentalization-based prenatal group intervention. Participants (94% White) were recruited in prenatal clinics and through online advertisements in Quebec, Canada. Both quantitative and qualitative data were collected from participants assigned to the STEP program (n = 42) and those receiving treatment-as-usual (TAU; n = 125). Women participating in STEP reported significant improvements in their relationships with their partners compared to those assigned to TAU. More precisely, they reported higher couple satisfaction, enhanced communication, and increased interest in their partners' emotional experience. The qualitative analysis further substantiated these results, with participants reporting having involved their partners in their pregnancy, shared their insights about themselves with their partners and gained fresh perspectives on their relationships. Participants in STEP also expressed sharing program materials with their partners and considered that such interventions should be extended to expecting fathers. This study underscores the potential of mentalization-based interventions to indirectly contribute to couple relationships, which may have positive implications for parenting and the infant., (© 2024 The Authors. Infant Mental Health Journal published by Wiley Periodicals LLC on behalf of Michigan Association for Infant Mental Health.)
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- 2024
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41. Heterogeneity in the longitudinal courses of global functioning in children at familial risk of major psychiatric disorders: Association with trauma and familial characteristics.
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Bureau A, Berthelot N, Ricard J, Lafrance C, Jomphe V, Dioni A, Fortin-Fabbro É, Boisvert MC, and Maziade M
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- Humans, Male, Child, Female, Adolescent, Longitudinal Studies, Child of Impaired Parents statistics & numerical data, Adverse Childhood Experiences statistics & numerical data, Depressive Disorder, Major genetics, Bipolar Disorder genetics, Schizophrenia genetics
- Abstract
Objectives: The extent to which heterogeneity in childhood risk trajectories may underlie later heterogeneity in schizophrenia (SZ), bipolar disorder (BP), and major depressive disorder (MDD) remains a chief question. Answers may optimally be found by studying the longitudinal trajectories of children born to an affected parent. We aimed to differentiate trajectories of global functioning and their sensitive periods from the age of 6 to 17 years in children at familial risk (FHRs)., Methods: First, a latent class mixed model analysis (LCMM) was applied to yearly ratings of the Children's Global Assessment Scale (CGAS) from the age of 6 to 17 years in 170 FHRs born to a parent affected by DSM-IV SZ (N = 37), BP (N = 82) or MDD (N = 51). Then, we compared the obtained Classes or trajectories of FHRs in terms of sex, parental diagnosis, IQ, child clinical status, childhood trauma, polygenic risk score (PRS), and outcome in transition to illness., Results: The LCMM on yearly CGAS trajectories identified a 4-class solution showing markedly different childhood and adolescence dynamic courses and temporal vulnerability windows marked by a functioning decline and a degree of specificity in parental diagnosis. Moreover, IQ, trauma exposure, PRS level, and timing of later transition to illness differentiated the trajectories. Almost half (46%) of the FHRs exhibited a good and stable global functioning trajectory., Conclusions: FHRs of major psychiatric disorders show heterogeneous functional decline during development associated with parental diagnosis, polygenic risk loading, and childhood trauma., (© 2023 The Authors. Bipolar Disorders published by John Wiley & Sons Ltd.)
- Published
- 2024
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42. Beyond abuse and neglect: validation of the childhood interpersonal trauma inventory in a community sample of adults.
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Legendre M, Milot T, Rousseau M, Lemieux R, Garon-Bissonnette J, and Berthelot N
- Abstract
Introduction: Childhood trauma is not restricted to abuse or neglect and other potentially traumatic experiences need to be pondered in practice and research. The study aimed to collect validity evidence of a new measure of exposure to a broad range of potentially traumatic experiences, the Childhood Interpersonal Trauma Inventory (CITI), by evaluating whether the CITI provides important additional information compared to a gold standard measure of childhood trauma., Methods: The sample consisted of 2,518 adults who completed the CITI and self-reported measures of trauma (Childhood Trauma Questionnaire; CTQ) and psychiatric symptoms (PTSD Checklist for DSM-5; Kessler Psychological Distress Scale; Dissociative Experiences Scale)., Results: First, the sensitivity to properly detect participants having been exposed to childhood maltreatment, as measured by the CTQ (here used as the gold standard), ranged between 64.81% and 88.71%, and the specificity ranged between 68.55% and 89.54%. Second, hierarchical regressions showed that the CITI predicted between 5.6 and 14.0% of the variance in psychiatric symptoms while the CTQ only captured a very small additional part of variance (0.3 to 0.7%). Finally, 25% (n = 407) of CTQ-negative participants screened positive at the CITI. The latter reported higher severity of psychiatric symptoms than participants without trauma, suggesting that the CITI permits the identification of adults exposed to significant traumas that remain undetected using other well-validated measures., Discussion: The findings underscore the utility of the CITI for research purposes and the latter's equivalence to a gold standard self-reported questionnaire to predict negative outcomes., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Legendre, Milot, Rousseau, Lemieux, Garon-Bissonnette and Berthelot.)
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- 2024
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43. Exploring the Associations of Personality and Sexual Health Using the DSM-5 Alternative Model for Personality Disorders.
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Deschênes M, Gamache D, Vaillancourt-Morel MP, Mayrand K, Nolin MC, Berthelot N, Mercerat C, and Savard C
- Subjects
- Humans, Female, Male, Adult, Middle Aged, Sexual Dysfunctions, Psychological psychology, Personal Satisfaction, Personality, Sexual Behavior psychology, Sexual Partners psychology, Personality Disorders psychology, Personality Disorders diagnosis, Diagnostic and Statistical Manual of Mental Disorders, Sexual Health
- Abstract
This study explored the relationships between sexual health indicators (i.e., sexual satisfaction, distress, and function) and the DSM-5 Alternative Model for Personality Disorders, a promising dimensional framework for assessing personality pathology. A sample of 489 participants seeking help in private practice clinics completed self-report measures of sexual satisfaction, distress, and function, as well as dyadic adjustment, psychological distress, romantic attachment, personality impairment, and pathological personality facets. Results first showed that participants reaching the cutoffs for a personality disorder had significantly higher sexual distress and lower sexual function compared to participants without a personality disorder. Second, path analyses controlling for psychological distress, dyadic adjustment, and romantic attachment revealed that, for women, the Criterion B Intimacy Avoidance facet was consistently linked with higher sexual distress and lower sexual satisfaction and function. For men, result patterns were more complex, linking Criterion B Separation Insecurity with high sexual distress, and Separation Insecurity and Intimacy Avoidance facets with low sexual function. In addition, Criterion B Irresponsibility, Rigid Perfectionism, as well as Criterion A Intimacy impairment were linked with higher sexual satisfaction. These findings improve our understanding of the links between personality and sexual health and provide support for considering personality difficulties in sexual health interventions.
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- 2024
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44. Post-traumatic-stress in the context of childhood maltreatment: pathways from attachment through mentalizing during the transition to parenthood.
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Ensink K, Bégin M, Martin-Gagnon G, Biberdzic M, Berthelot N, Normandin L, Fonagy P, Bernazzani O, and Borelli JL
- Abstract
Introduction: This study aimed to clarify the role of mentalizing in pathways from attachment to Post Traumatic Stress Symptoms (PTSS) in survivors of childhood maltreatment (CM). We focused on the transition to parenting, a critical period for reworking parenting representations to reduce intergenerational maltreatment cycles., Method: Study participants included 100 pregnant CM survivors. We assessed PTSS with the SCID and attachment and mentalizing with the Adult Attachment Interview (AAI), which was rated for Attachment and Reflective Functioning (RF)., Results: Regarding Re-experiencing trauma symptoms, the results of the path analysis were consistent with mediation. CM survivors' mentalizing about their early relationships with their parents (RF-Other) directly impacted Re-experiencing trauma symptoms, and attachment had an effect on Re-experiencing trauma symptoms through mentalizing (RF-Other). Regarding Arousal/Reactivity symptoms, the results of the pathways analysis were consistent with partial mediation by mentalizing about early relationships with parents (RF-Other). In addition to the pathway from attachment via mentalizing (RF-Other) to Arousal/Reactivity, the pathway between attachment and Arousal/Reactivity also remained significant., Discussion: This study provides new evidence of a mentalizing and attachment model of PTSS in CM survivors. The findings indicate that increased mentalizing about early relationships with parents is an important process associated with lower PTSS. Finally, we discuss the implications of developing interventions for CM survivors to reduce PTSS. Scaffolding the development of mentalizing regarding attachment relationships in which CM occurred may help CM survivors reduce the intrusion of traumatic memories and decrease trauma-related arousal and reactivity symptoms. Interventions to help CM survivors mentalize regarding parents and attachment relationships in which trauma occurred may be particularly important during the transition to parenting when activation of representations of parenting can trigger PTSS., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Ensink, Bégin, Martin-Gagnon, Biberdzic, Berthelot, Normandin, Fonagy, Bernazzani and Borelli.)
- Published
- 2023
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45. A deeper look at the association between childhood maltreatment and reflective functioning.
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Garon-Bissonnette J, Dubois-Comtois K, St-Laurent D, and Berthelot N
- Subjects
- Adult, Humans, Child, Female, Pregnancy, Retrospective Studies, Parents, Surveys and Questionnaires, Object Attachment, Child Abuse
- Abstract
Childhood maltreatment is theorized as impeding the development of reflective functioning (RF; ability to perceive and interpret oneself and others in terms of mental states). However, previous research typically failed to support this association or yielded small sized and mixed associations. This study aims to provide a deeper look at the association between childhood maltreatment and RF by characterizing two non-mentalizing categories. One-hundred-and-sixteen pregnant women (mean age = 27.62, SD = 4.52) from the community (48.3% with a university degree, 96.5% in a relationship with the other parent) retrospectively reported on childhood abuse and neglect using the Childhood Trauma Questionnaire. They also participated in the Adult Attachment Interview subsequently coded using the Reflective Functioning Scale. Participants with poor to low RF were allocated to one of two groups (disavowal-distancing or distorted-inconsistent) using indicators provided in the RF Scale. No association was found between childhood maltreatment and overall RF when controlling for education level. A multinomial logistic regression revealed that childhood maltreatment was strongly predictive of a disrupted, over-analytical and inconsistent reflection about mental states but not of a tendency to discourse little about mental states. This tendency was rather only predicted by education level. Findings suggest that childhood maltreatment would lead to specific impairments in RF and that not considering how individuals fail to mentalize about attachment relationships may mask strong associations between RF and its determinants and correlates, including childhood maltreatment.
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- 2023
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46. STEP-COVID: a pilot study of a prenatal intervention for pregnant women during the COVID-19 pandemic.
- Author
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Berthelot N, Garon-Bissonnette J, Drouin-Maziade C, Bergeron V, and Sériès T
- Subjects
- Female, Humans, Pregnancy, Pandemics, Pilot Projects, Prenatal Care methods, Pregnant People psychology, COVID-19 epidemiology
- Abstract
The COVID-19 pandemic has been associated with a global increase in psychological distress in pregnant women. This study evaluated the effects of STEP-COVID, a six-session mentalization-based prenatal group program offered online during the COVID-19 pandemic. The 100 participants were allocated to STEP-COVID or to the natural trajectory of prenatal care. Pre- and post-intervention assessments included measures of psychological distress, post-traumatic symptoms and positive affectivity. Perception of change during pregnancy on resilience-promoting factors was also assessed at post-intervention. A significant decrease in psychological distress and post-traumatic symptoms and an increase in positive affectivity were observed in participants in the intervention condition, whereas only post-traumatic symptoms improved in the control condition. Women who participated in STEP-COVID also reported greater changes during pregnancy on resilience-promoting factors than women in the control condition. Results hold promise for buffering the effect of the pandemic on the mental health of pregnant women using brief online interventions. Clinical trial registration: NCT05419167 (15/06/2022)., (© 2023. The Author(s).)
- Published
- 2023
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47. Foster family assessment: The assessor's perspective - A qualitative study.
- Author
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Caron R, Poitras K, St-Laurent D, Joly MP, Poirier MA, Berthelot N, and Dubois-Comtois K
- Subjects
- Adolescent, Caregivers psychology, Child, Family, Humans, Prospective Studies, Qualitative Research, Child Protective Services, Foster Home Care
- Abstract
Children in foster care are more likely to exhibit emotional, behavioral, social, and developmental problems. Accordingly, foster families should provide them with a safe family environment that promotes their development. Therefore, to ensure that foster families adequately meet children's needs, it is crucial for youth protection services to properly assess prospective foster family applicants. However, the specific assessment methods are understudied. This study aims to capture the experiences of caseworkers and the challenges they face in assessing and selecting potential foster caregivers, as well as their needs for support to perform the assessments. Focus groups were held in child protection services agencies in the province of Québec (Canada). Three group interviews with a total of 15 caseworkers were transcribed and subjected to content analysis using NVivo 11. The caseworkers identified nine most important dimensions for assessing prospective foster families, notably motivation and engagement. Differences in the assessment process between caseworkers were observed, particularly for the type of foster family assessed. The caseworkers reported certain common needs for assessment training, primarily in interview techniques and the handling of multicultural issues. They also complained of lack of time allocated for clinical support during assessments. The results call for collaborative efforts between researchers and practitioners to provide appropriate training and tools to support the assessment process., (Copyright © 2021 Elsevier Ltd. All rights reserved.)
- Published
- 2022
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48. Development and validation of a self-report measure assessing failures in the mentalization of trauma and adverse relationships.
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Berthelot N, Savard C, Lemieux R, Garon-Bissonnette J, Ensink K, and Godbout N
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- Adult, Child, Female, Humans, Male, Parenting, Self Report, Child Abuse, Intimate Partner Violence, Mentalization, Surveys and Questionnaires
- Abstract
Background: The way people process trauma and adverse relationships may be more predictive of subsequent adaptation than trauma exposure in itself. However, there is currently no self-report instrument assessing failures in the mentalization of trauma and adverse relationships., Objective: We developed the Failure to Mentalize Trauma Questionnaire (FMTQ) and evaluated its psychometric properties. The FMTQ is a 29-item self-report instrument designed to assess different indications of failures in the mentalization of trauma and adverse relationships., Participants and Setting: A total of 975 participants (84 % women; 37 % exposed to child maltreatment) were recruited in the course of larger research protocols on parenting., Methods: Participants completed the FMTQ and measures of childhood maltreatment, psychopathology (post-traumatic stress symptoms, dissociative symptoms, level of personality dysfunction), general mentalization and intimate partner violence., Results: Exploratory factor analysis, supported by a confirmatory factor analysis, identified seven factors with good internal consistency that corresponded to different types of failures in the mentalization of trauma and adverse relationships and that loaded on a general factor. A dose-effect association was observed between the severity of childhood maltreatment, and the severity of failures in the mentalization of trauma and adverse relationships (r
s = .49, p < .01). The FMTQ total score explained a significant proportion of variance in psychopathology and intimate partner violence, both in participants with histories of childhood maltreatment and participants without childhood maltreatment., Conclusion: The FMTQ is a promising, concise and efficient measure of failures in the mentalization of trauma and adverse relationships that may facilitate clinical screening and research with adults who experienced trauma., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)- Published
- 2022
- Full Text
- View/download PDF
49. Maternal childhood abuse and neglect predicts offspring development in early childhood: The roles of reflective functioning and child sex.
- Author
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Garon-Bissonnette J, Duguay G, Lemieux R, Dubois-Comtois K, and Berthelot N
- Subjects
- Child, Child Development, Child, Preschool, Female, Humans, Male, Mothers, Pregnancy, Psychometrics, Child Abuse, Mentalization
- Abstract
Background: Recent evidence suggests that offspring of mothers having been exposed to childhood abuse and neglect (CA&N) are at increased risk of developmental problems and that boys are more affected by maternal CA&N than girls. Since impairments in reflective functioning (RF) have been associated with maternal CA&N and offspring development, RF could represent a key mechanism in these intergenerational risk trajectories., Objective: This study evaluated mediating (RF) and moderating (child sex) mechanisms in the association between maternal CA&N and child development., Participants and Setting: In a longitudinal setting, 111 mothers completed measures during pregnancy and between 11 and 36 months postpartum., Methods: CA&N and impairments in RF were assessed during pregnancy and offspring development was measured during the longitudinal follow-up using the Ages and Stages Questionnaires (ASQ-3). Child development was operationalized in two ways: using the global score at the ASQ-3 and using a dichotomous score of accumulation of delays across domains of development., Results: Structural equation modeling indicated that RF mediated the association between maternal CA&N and offspring development. Child sex moderated the association between CA&N and the clustering of developmental problems (Wald = 5.88, p = 0.02), with boys being particularly likely to accumulate developmental delays when their mother experienced CA&N (RR = 2.62). Accumulation of developmental problems was associated with impairments in maternal RF in girls and with maternal exposure to CA&N in boys., Conclusions: Results provide novel insights on the role of mentalization and child sex in the association between maternal CA&N and child development., (Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
50. Socioemotional development in infants of pregnant women during the COVID-19 pandemic: the role of prenatal and postnatal maternal distress.
- Author
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Duguay G, Garon-Bissonnette J, Lemieux R, Dubois-Comtois K, Mayrand K, and Berthelot N
- Abstract
Background: An upsurge in psychological distress was documented in pregnant women during the COVID-19 pandemic. We investigated with a longitudinal design whether prenatal and postnatal maternal distress during the COVID-19 pandemic was associated with lower infant socioemotional development., Methods: Pregnant women (N = 468, M
age = 30,00, 97.6% White) were recruited during the first COVID-19 mandatory lockdown in Quebec, Canada, from April 2nd to April 13th 2020 and were re-contacted at two months postpartum to complete self-reported measures of general (i.e. not specifically related to the COVID-19 pandemic) anxio-depressive symptoms and infant development. Structural equation modeling analyses were performed using maximum likelihood parameter estimation., Results: Higher maternal prenatal distress significantly contributed to poorer infant socioemotional development. A mediation model showed that postnatal distress significantly mediated the association between prenatal distress and infant socioemotional development, whereas the direct effect of prenatal distress was no longer significant. Prenatal and postnatal maternal distress accounted for 13.7% of the variance in infant socioemotional development., Conclusion: Our results call for special means of clinical surveillance in mothers and for innovative (online) interventions aiming to support maternal mental health during pregnancy and after delivery., (© 2022. The Author(s).)- Published
- 2022
- Full Text
- View/download PDF
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