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347 results on '"Berrien-Elliott, Melissa"'

1. A “Prime and Expand” strategy using the multifunctional fusion proteins to generate memory-like NK cells for cell therapy

Author

Shrestha, Niraj, Dee, Michael J., Chaturvedi, Pallavi, Leclerc, Gilles M., Mathyer, Mary, Dufour, Celeste, Arthur, Laura, Becker-Hapak, Michelle, Foster, Mark, McClain, Ethan, Pena, Natalia Valderrama, Kage, Karen, Zhu, Xiaoyun, George, Varghese, Liu, Bai, Egan, Jack, Echeverri, Christian, Wang, Meng, You, Lijing, Kong, Lin, Li, Liying, Berrien-Elliott, Melissa M., Cooper, Matthew L., Fehniger, Todd A., Rhode, Peter R., and Wong, Hing C.

Published
2024
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2. Induced CD8[alpha] identifies human NK cells with enhanced proliferative fitness and modulates NK cell activation

Author

Cubitt, Celia C., Wong, Pamela, Dorando, Hannah K., Foltz, Jennifer A., Tran, Jennifer, Marsala, Lynne, Marin, Nancy D., Foster, Mark, Schappe, Timothy, Fatima, Hijab, Becker-Hapak, Michelle, Zhou, Alice Y., Hwang, Kimberly, Jacobs, Miriam T., Russler-Germain, David A., Mace, Emily M., Berrien-Elliott, Melissa M., Payton, Jacqueline E., and Fehniger, Todd A.

Subjects
Control, Influence, Identification and classification, Physiological aspects, Growth, Company growth, CD8 lymphocytes -- Influence -- Physiological aspects, Killer cells -- Identification and classification -- Growth -- Control
Abstract

Introduction NK cells are innate lymphoid cells that protect the host from infection and malignant transformation through direct cytotoxicity and communication via cytokine and chemokine production (1-3). Human NK cells [...], The surface receptor CD8[alpha] is present on 20%-80% of human (but not mouse) NK cells, yet its function on NK cells remains poorly understood. CD8[alpha] expression on donor NK cells was associated with a lack of therapeutic responses in patients with leukemia in prior studies, thus, we hypothesized that CD8[alpha] may affect critical NK cell functions. Here, we discovered that CD8[[alpha].sup.-] NK cells had improved control of leukemia in xenograft models compared with CD8[[alpha].sup.+] NK cells, likely due to an enhanced capacity for proliferation. Unexpectedly, we found that CD8[alpha] expression was induced on approximately 30% of previously CD8[[alpha].sup.- ] NK cells following IL-15 stimulation. These induced CD8[[alpha].sup.+] (iCD8[[alpha].sup.+]) NK cells had the greatest proliferation, responses to IL-15 signaling, and metabolic activity compared with those that sustained existing CD8[alpha] expression (sustained CD8[[alpha].sup.+]) or those that remained CD8[[alpha].sup.-] (persistent CD8[alpha]). These iCD8[[alpha].sup.+] cells originated from an IL- 15R[[beta].sup.hi] NK cell population, with CD8[alpha] expression dependent on the transcription factor RUNX3. Moreover, CD8A CRISPR/Cas9 deletion resulted in enhanced responses through the activating receptor NKp30, possibly by modulating KIR inhibitory function. Thus, CD8[alpha] status identified human NK cell capacity for IL-15-induced proliferation and metabolism in a time-dependent fashion, and its presence had a suppressive effect on NK cell-activating receptors.

Published
2024
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4. Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction

Author

Selli, Mehmet Emrah, Landmann, Jack H., Terekhova, Marina, Lattin, John, Heard, Amanda, Hsu, Yu-Sung, Chang, Tien-Ching, Chang, Jufang, Warrington, John, Ha, Helen, Kingston, Natalie, Hogg, Graham, Slade, Michael, Berrien-Elliott, Melissa M., Foster, Mark, Kersting-Schadek, Samantha, Gruszczynska, Agata, DeNardo, David, Fehniger, Todd A., Artyomov, Maxim, and Singh, Nathan

Published
2023
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6. MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus.

Author

Wong, Pamela, Leong, Jeffrey W., Sohn, Hyogon, Chang, Lily, Keppel, Catherine R., Neal, Carly C., Cubitt, Celia C., Yao, Tony, Keppel, Molly P., Tran, Jennifer, Burdi, Allison, Hwang, Kimberly, Fogel, Leslie A., Schappe, Timothy, Marsala, Lynne, Berrien‐Elliott, Melissa M., Wagner, Julia A., Schneider, Stephanie E., Sullivan, Ryan P., and Pingel, Jeanette T.

Subjects
INNATE lymphoid cells, KILLER cells, LIVER cells, T cells, BONE marrow
Abstract

Natural killer (NK) cells are innate lymphoid cells that protect a host from viral infections and malignancies. MicroRNA‐146a (miR‐146a) is an important regulator of immune function that is highly expressed in NK cells and is further upregulated during murine cytomegalovirus (MCMV) infection. Here we utilized mice with a global targeted deletion of miR‐146a to understand its impact on the innate immune responses to MCMV infection. MiR‐146a−/− mice were protected from lethal MCMV infection, which was intrinsic to the hematopoietic compartment based on bone marrow chimera experiments. NK cell depletion abrogated this protection, implicating NK cells as critical for the miR‐146a−/− protection from MCMV. Surprisingly, NK cells from miR‐146a‐deficient mice were largely similar to control NK cells with respect to development, maturation, trafficking, and effector functions. However, miR‐146a−/− mice had increased NK cell numbers and frequency of the most mature Stage IV (CD27−CD11b+) NK cells in the liver at baseline, enhanced STAT1 phosphorylation, and increased selective expansion of Ly49H+ NK cells and T cells during MCMV infection. This study demonstrates a critical role for miR‐146a in the host response to MCMV, arising from mechanisms that include increased NK cell numbers and early T‐cell expansion. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Memory-like differentiation enhances NK cell responses against colorectal cancer.

Author

Marin, Nancy D., Becker-Hapak, Michelle, Song, Wilbur M., Alayo, Quazim A., Marsala, Lynne, Sonnek, Naomi, Berrien-Elliott, Melissa M., Foster, Mark, Foltz, Jennifer A., Tran, Jennifer, Wong, Pamela, Cubitt, Celia C., Pence, Patrick, Hwang, Kimberly, Zhou, Alice Y., Jacobs, Miriam T., Schappe, Timothy, Russler-Germain, David A., Fields, Ryan C., and Ciorba, Matthew A.

Subjects
INNATE lymphoid cells, KILLER cells, CELL physiology, IMMUNE checkpoint proteins, INCURABLE diseases
Abstract

Metastatic (m) colorectal cancer (CRC) is an incurable disease with a poor prognosis and thus remains an unmet clinical need. Immune checkpoint blockade (ICB)-based immunotherapy is effective for mismatch repair-deficient (dMMR)/microsatellite instability-high (MSI-H) mCRC patients, but it does not benefit the majority of mCRC patients. NK cells are innate lymphoid cells with potent effector responses against a variety of tumor cells but are frequently dysfunctional in cancer patients. Memory-like (ML) NK cells differentiated after IL-12/IL-15/IL-18 activation overcome many challenges to effective NK cell anti-tumor responses, exhibiting enhanced recognition, function, and in vivo persistence. We hypothesized that ML differentiation enhances the NK cell responses to CRC. Compared to conventional (c) NK cells, ML NK cells displayed increased IFN-γ production against both CRC cell lines and primary patient-derived CRC spheroids. ML NK cells also exhibited improved killing of CRC target cells in vitro in short-term and sustained cytotoxicity assays, as well as in vivo in NSG mice. Mechanistically, enhanced ML NK cell responses were dependent on the activating receptor NKG2D as its blockade significantly decreased ML NK cell functions. Compared to cNK cells, ML NK cells exhibited greater antibody-dependent cytotoxicity when targeted against CRC by cetuximab. ML NK cells from healthy donors and mCRC patients exhibited increased anti-CRC responses. Collectively, our findings demonstrate that ML NK cells exhibit enhanced responses against CRC targets, warranting further investigation in clinical trials for mCRC patients, including those who have failed ICB. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Phase 1/dose expansion trial of brentuximab vedotin and lenalidomide in relapsed or refractory diffuse large B-cell lymphoma

Author

Ward, Jeffrey P., Berrien-Elliott, Melissa M., Gomez, Felicia, Luo, Jingqin, Becker-Hapak, Michelle, Cashen, Amanda F., Wagner-Johnston, Nina D., Maddocks, Kami, Mosior, Matthew, Foster, Mark, Krysiak, Kilannin, Schmidt, Alina, Skidmore, Zachary L., Desai, Sweta, Watkins, Marcus P., Fischer, Anne, Griffith, Malachi, Griffith, Obi L., Fehniger, Todd A., and Bartlett, Nancy L.

Published
2022
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10. Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant

Author

Bednarski, Jeffrey J., Zimmerman, Clare, Berrien-Elliott, Melissa M., Foltz, Jennifer A., Becker-Hapak, Michelle, Neal, Carly C., Foster, Mark, Schappe, Timothy, McClain, Ethan, Pence, Patrick P., Desai, Sweta, Kersting-Schadek, Samantha, Wong, Pamela, Russler-Germain, David A., Fisk, Bryan, Lie, Wen-Rong, Eisele, Jeremy, Hyde, Stephanie, Bhatt, Sima T., Griffith, Obi L., Griffith, Malachi, Petti, Allegra A., Cashen, Amanda F., and Fehniger, Todd A.

Published
2022
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11. CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas

Author

Gang, Margery, Marin, Nancy D., Wong, Pamela, Neal, Carly C., Marsala, Lynne, Foster, Mark, Schappe, Timothy, Meng, Wei, Tran, Jennifer, Schaettler, Maximilian, Davila, Marco, Gao, Feng, Cashen, Amanda F., Bartlett, Nancy L., Mehta-Shah, Neha, Kahl, Brad S., Kim, Miriam Y., Cooper, Matthew L., DiPersio, John F., Berrien-Elliott, Melissa M., and Fehniger, Todd A.

Published
2020
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15. Anti-myeloma efficacy of BCMA CAR-iNKT is enhanced with a long-acting IL-7, rhIL7hyFc

Author

O'Neal, Julie, primary, Cooper, Matthew L., additional, Ritchey, Julie K., additional, Gladney, Susan, additional, Niswonger, Jessica, additional, Sofía González, L., additional, Street, Emily, additional, Haas, Gabriel J., additional, Carter, Alun, additional, Amayta, Parmeshwar N., additional, Gao, Feng, additional, Ha Lee, Byung, additional, Choi, Donghoon, additional, Berrien-Elliott, Melissa, additional, Zhou, Alice, additional, Fehniger, Todd A., additional, Rettig, Mike P., additional, and DiPersio, John F., additional

Published
2024
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16. MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells

Author

Berrien-Elliott, Melissa M., Sun, Yaping, Neal, Carly, Ireland, Aaron, Trissal, Maria C., Sullivan, Ryan P., Wagner, Julia A., Leong, Jeffrey W., Wong, Pamela, Mah-Som, Annelise Y., Wong, Terrence N., Schappe, Timothy, Keppel, Catherine R., Cortez, Victor S., Stamatiades, Efstathios G., Li, Ming O., Colonna, Marco, Link, Daniel C., French, Anthony R., Cooper, Megan A., Wang, Wei-Le, Boldin, Mark P., Reddy, Pavan, and Fehniger, Todd A.

Published
2019
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17. Donor-Derived Memory-like NK Cells for the Treatment of Children and Young Adults with Relapsed AML Following Allo-HCT

Author

Pfeiffer, Thomas, primary, Zimmerman, Clare, additional, Berrien-Elliott, Melissa M, additional, Foltz, Jennifer, additional, Becker-Hapak, Michelle, additional, Neal, Carly, additional, Foster, Mark, additional, Schappe, Timothy, additional, McClain, Ethan, additional, Pence, Patrick, additional, Desai, Sweta, additional, Wong, Pamela, additional, Russler-Germain, David, additional, Fisk, Bryan, additional, Wen-Rong, Lie, additional, Eisele, Jeremy, additional, Hyde, Stephanie, additional, Bhatt, Sima, additional, Griffith, Obi, additional, Griffith, Malachi, additional, Rueve, Joseph, additional, Pureti, Sushanth, additional, Cashen, Amanda, additional, Bednarski, Jeffrey J, additional, and Fehniger, Todd A, additional

Published
2024
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18. First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Author

Romee, Rizwan, Cooley, Sarah, Berrien-Elliott, Melissa M., Westervelt, Peter, Verneris, Michael R., Wagner, John E., Weisdorf, Daniel J., Blazar, Bruce R., Ustun, Celalettin, DeFor, Todd E., Vivek, Sithara, Peck, Lindsey, DiPersio, John F., Cashen, Amanda F., Kyllo, Rachel, Musiek, Amy, Schaffer, András, Anadkat, Milan J., Rosman, Ilana, Miller, Daniel, Egan, Jack O., Jeng, Emily K., Rock, Amy, Wong, Hing C., Fehniger, Todd A., and Miller, Jeffrey S.

Published
2018
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19. Supplementary Figure S7 from Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer

Author

Jacobs, Miriam T., primary, Wong, Pamela, primary, Zhou, Alice Y., primary, Becker-Hapak, Michelle, primary, Marin, Nancy D., primary, Marsala, Lynne, primary, Foster, Mark, primary, Foltz, Jennifer A., primary, Cubitt, Celia C., primary, Tran, Jennifer, primary, Russler-Germain, David A., primary, Neal, Carly, primary, Kersting-Schadek, Samantha, primary, Chang, Lily, primary, Schappe, Timothy, primary, Pence, Patrick, primary, McClain, Ethan, primary, Zevallos, Jose P., primary, Rich, Jason T., primary, Paniello, Randal C., primary, Jackson, Ryan S., primary, Pipkorn, Patrik, primary, Adkins, Douglas R., primary, DeSelm, Carl J., primary, Berrien-Elliott, Melissa M., primary, Puram, Sidharth V., primary, and Fehniger, Todd A., primary

Published
2023
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20. Data from Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer

Author

Jacobs, Miriam T., primary, Wong, Pamela, primary, Zhou, Alice Y., primary, Becker-Hapak, Michelle, primary, Marin, Nancy D., primary, Marsala, Lynne, primary, Foster, Mark, primary, Foltz, Jennifer A., primary, Cubitt, Celia C., primary, Tran, Jennifer, primary, Russler-Germain, David A., primary, Neal, Carly, primary, Kersting-Schadek, Samantha, primary, Chang, Lily, primary, Schappe, Timothy, primary, Pence, Patrick, primary, McClain, Ethan, primary, Zevallos, Jose P., primary, Rich, Jason T., primary, Paniello, Randal C., primary, Jackson, Ryan S., primary, Pipkorn, Patrik, primary, Adkins, Douglas R., primary, DeSelm, Carl J., primary, Berrien-Elliott, Melissa M., primary, Puram, Sidharth V., primary, and Fehniger, Todd A., primary

Published
2023
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21. Supplementary Table S1 from Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer

Author

Jacobs, Miriam T., primary, Wong, Pamela, primary, Zhou, Alice Y., primary, Becker-Hapak, Michelle, primary, Marin, Nancy D., primary, Marsala, Lynne, primary, Foster, Mark, primary, Foltz, Jennifer A., primary, Cubitt, Celia C., primary, Tran, Jennifer, primary, Russler-Germain, David A., primary, Neal, Carly, primary, Kersting-Schadek, Samantha, primary, Chang, Lily, primary, Schappe, Timothy, primary, Pence, Patrick, primary, McClain, Ethan, primary, Zevallos, Jose P., primary, Rich, Jason T., primary, Paniello, Randal C., primary, Jackson, Ryan S., primary, Pipkorn, Patrik, primary, Adkins, Douglas R., primary, DeSelm, Carl J., primary, Berrien-Elliott, Melissa M., primary, Puram, Sidharth V., primary, and Fehniger, Todd A., primary

Published
2023
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22. Memory-like Differentiation, Tumor-Targeting mAbs, and Chimeric Antigen Receptors Enhance Natural Killer Cell Responses to Head and Neck Cancer

Author

Jacobs, Miriam T., primary, Wong, Pamela, additional, Zhou, Alice Y., additional, Becker-Hapak, Michelle, additional, Marin, Nancy D., additional, Marsala, Lynne, additional, Foster, Mark, additional, Foltz, Jennifer A., additional, Cubitt, Celia C., additional, Tran, Jennifer, additional, Russler-Germain, David A., additional, Neal, Carly, additional, Kersting-Schadek, Samantha, additional, Chang, Lily, additional, Schappe, Timothy, additional, Pence, Patrick, additional, McClain, Ethan, additional, Zevallos, Jose P., additional, Rich, Jason T., additional, Paniello, Randal C., additional, Jackson, Ryan S., additional, Pipkorn, Patrik, additional, Adkins, Douglas R., additional, DeSelm, Carl J., additional, Berrien-Elliott, Melissa M., additional, Puram, Sidharth V., additional, and Fehniger, Todd A., additional

Published
2023
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26. T-BET and EOMES sustain mature human NK cell identity and antitumor function

Author

Wong, Pamela, primary, Foltz, Jennifer A., additional, Chang, Lily, additional, Neal, Carly C., additional, Yao, Tony, additional, Cubitt, Celia C., additional, Tran, Jennifer, additional, Kersting-Schadek, Samantha, additional, Palakurty, Sathvik, additional, Jaeger, Natalia, additional, Russler-Germain, David A., additional, Marin, Nancy D., additional, Gang, Margery, additional, Wagner, Julia A., additional, Zhou, Alice Y., additional, Jacobs, Miriam T., additional, Foster, Mark, additional, Schappe, Timothy, additional, Marsala, Lynne, additional, McClain, Ethan, additional, Pence, Patrick, additional, Becker-Hapak, Michelle, additional, Fisk, Bryan, additional, Petti, Allegra A., additional, Griffith, Obi L., additional, Griffith, Malachi, additional, Berrien-Elliott, Melissa M., additional, and Fehniger, Todd A., additional

Published
2023
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27. Brief IL-12, IL-15, IL-18 activation drives the acquisition of two distinct memory-like NK cell states

Author

Foltz, Jennifer Ann, primary, Tran, Jennifer, additional, Fisk, Bryan, additional, Wong, Pamela, additional, Khan, Saad M., additional, Berrien-Elliott, Melissa M., additional, Becker-Hapak, Michelle, additional, Russler-Germain, David A., additional, Marsala, Lynne, additional, Bednarski, Jeffrey J., additional, Zimmerman, Clare, additional, Cubitt, Celia C., additional, Marin, Nancy D., additional, Zhou, Alice Y., additional, Jacobs, Miriam T., additional, Foster, Mark, additional, Schappe, Timothy, additional, Pence, Patrick, additional, Cashen, Amanda, additional, Griffith, Obi L., additional, Griffith, Malachi, additional, Petti, Allegra A., additional, and Fehniger, Todd A, additional

Published
2023
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28. Combined IL-12, IL-15 and IL-18 activation induces epigenetic changes in human NK cells during the memory-like state transition

Author

Tran, Jennifer, primary, Wong, Pamela, additional, Fan, Changxu, additional, Russler-Germain, David, additional, Cubitt, Celia C, additional, Marin, Nancy D, additional, Schappe, Timothy, additional, Berrien-Elliott, Melissa, additional, Wang, Ting, additional, Foltz, Jennifer A, additional, and Fehniger, Todd A, additional

Published
2023
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30. Supplementary Table 5 from A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

Author

Becker-Hapak, Michelle K., primary, Shrestha, Niraj, primary, McClain, Ethan, primary, Dee, Michael J., primary, Chaturvedi, Pallavi, primary, Leclerc, Gilles M., primary, Marsala, Lynne I., primary, Foster, Mark, primary, Schappe, Timothy, primary, Tran, Jennifer, primary, Desai, Sweta, primary, Neal, Carly C., primary, Pence, Patrick, primary, Wong, Pamela, primary, Wagner, Julia A., primary, Russler-Germain, David A., primary, Zhu, Xiaoyun, primary, Spanoudis, Catherine M., primary, Gallo, Victor L., primary, Echeverri, Christian A., primary, Ramirez, Laritza L., primary, You, Lijing, primary, Egan, Jack O., primary, Rhode, Peter R., primary, Jiao, Jin-an, primary, Muniz, Gabriela J., primary, Jeng, Emily K., primary, Prendes, Caitlin A., primary, Sullivan, Ryan P., primary, Berrien-Elliott, Melissa M., primary, Wong, Hing C., primary, and Fehniger, Todd A., primary

Published
2023
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31. Data from A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

Author

Becker-Hapak, Michelle K., primary, Shrestha, Niraj, primary, McClain, Ethan, primary, Dee, Michael J., primary, Chaturvedi, Pallavi, primary, Leclerc, Gilles M., primary, Marsala, Lynne I., primary, Foster, Mark, primary, Schappe, Timothy, primary, Tran, Jennifer, primary, Desai, Sweta, primary, Neal, Carly C., primary, Pence, Patrick, primary, Wong, Pamela, primary, Wagner, Julia A., primary, Russler-Germain, David A., primary, Zhu, Xiaoyun, primary, Spanoudis, Catherine M., primary, Gallo, Victor L., primary, Echeverri, Christian A., primary, Ramirez, Laritza L., primary, You, Lijing, primary, Egan, Jack O., primary, Rhode, Peter R., primary, Jiao, Jin-an, primary, Muniz, Gabriela J., primary, Jeng, Emily K., primary, Prendes, Caitlin A., primary, Sullivan, Ryan P., primary, Berrien-Elliott, Melissa M., primary, Wong, Hing C., primary, and Fehniger, Todd A., primary

Published
2023
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32. Abstract 6418: xWU-NK-101 as salvage therapy post immune checkpoint blockade (ICB)

Author

Leedom, Tom A., primary, Muz, Barbara, additional, Vadakekolathu, Jaykumar, additional, Muth, John J., additional, Li, Xiao-Hua, additional, Watson, Gregory, additional, Magee, Kristaan, additional, Sullivan, Ryan P., additional, Berrien-Elliott, Melissa, additional, Fenigher, Todd, additional, Rutella, Sergio, additional, Cooper, Matthew L., additional, Kabakibi, Ayman, additional, and Davidson-Moncada, Jan K., additional

Published
2023
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33. Supplementary Figure Legends from A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

Author

Becker-Hapak, Michelle K., primary, Shrestha, Niraj, primary, McClain, Ethan, primary, Dee, Michael J., primary, Chaturvedi, Pallavi, primary, Leclerc, Gilles M., primary, Marsala, Lynne I., primary, Foster, Mark, primary, Schappe, Timothy, primary, Tran, Jennifer, primary, Desai, Sweta, primary, Neal, Carly C., primary, Pence, Patrick, primary, Wong, Pamela, primary, Wagner, Julia A., primary, Russler-Germain, David A., primary, Zhu, Xiaoyun, primary, Spanoudis, Catherine M., primary, Gallo, Victor L., primary, Echeverri, Christian A., primary, Ramirez, Laritza L., primary, You, Lijing, primary, Egan, Jack O., primary, Rhode, Peter R., primary, Jiao, Jin-an, primary, Muniz, Gabriela J., primary, Jeng, Emily K., primary, Prendes, Caitlin A., primary, Sullivan, Ryan P., primary, Berrien-Elliott, Melissa M., primary, Wong, Hing C., primary, and Fehniger, Todd A., primary

Published
2023
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34. Supplementary Table 4 from A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

Author

Becker-Hapak, Michelle K., primary, Shrestha, Niraj, primary, McClain, Ethan, primary, Dee, Michael J., primary, Chaturvedi, Pallavi, primary, Leclerc, Gilles M., primary, Marsala, Lynne I., primary, Foster, Mark, primary, Schappe, Timothy, primary, Tran, Jennifer, primary, Desai, Sweta, primary, Neal, Carly C., primary, Pence, Patrick, primary, Wong, Pamela, primary, Wagner, Julia A., primary, Russler-Germain, David A., primary, Zhu, Xiaoyun, primary, Spanoudis, Catherine M., primary, Gallo, Victor L., primary, Echeverri, Christian A., primary, Ramirez, Laritza L., primary, You, Lijing, primary, Egan, Jack O., primary, Rhode, Peter R., primary, Jiao, Jin-an, primary, Muniz, Gabriela J., primary, Jeng, Emily K., primary, Prendes, Caitlin A., primary, Sullivan, Ryan P., primary, Berrien-Elliott, Melissa M., primary, Wong, Hing C., primary, and Fehniger, Todd A., primary

Published
2023
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35. Supplementary Figures 1-8 and Tables 1-3 from A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy

Author

Becker-Hapak, Michelle K., primary, Shrestha, Niraj, primary, McClain, Ethan, primary, Dee, Michael J., primary, Chaturvedi, Pallavi, primary, Leclerc, Gilles M., primary, Marsala, Lynne I., primary, Foster, Mark, primary, Schappe, Timothy, primary, Tran, Jennifer, primary, Desai, Sweta, primary, Neal, Carly C., primary, Pence, Patrick, primary, Wong, Pamela, primary, Wagner, Julia A., primary, Russler-Germain, David A., primary, Zhu, Xiaoyun, primary, Spanoudis, Catherine M., primary, Gallo, Victor L., primary, Echeverri, Christian A., primary, Ramirez, Laritza L., primary, You, Lijing, primary, Egan, Jack O., primary, Rhode, Peter R., primary, Jiao, Jin-an, primary, Muniz, Gabriela J., primary, Jeng, Emily K., primary, Prendes, Caitlin A., primary, Sullivan, Ryan P., primary, Berrien-Elliott, Melissa M., primary, Wong, Hing C., primary, and Fehniger, Todd A., primary

Published
2023
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36. Data from Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations with Response after Adoptive Immunotherapy for Leukemia

Author

Berrien-Elliott, Melissa M., primary, Cashen, Amanda F., primary, Cubitt, Celia C., primary, Neal, Carly C., primary, Wong, Pamela, primary, Wagner, Julia A., primary, Foster, Mark, primary, Schappe, Timothy, primary, Desai, Sweta, primary, McClain, Ethan, primary, Becker-Hapak, Michelle, primary, Foltz, Jennifer A., primary, Cooper, Matthew L., primary, Jaeger, Natalia, primary, Srivatsan, Sridhar Nonavinkere, primary, Gao, Feng, primary, Romee, Rizwan, primary, Abboud, Camille N., primary, Uy, Geoffrey L., primary, Westervelt, Peter, primary, Jacoby, Meagan A., primary, Pusic, Iskra, primary, Stockerl-Goldstein, Keith E., primary, Schroeder, Mark A., primary, DiPersio, John, primary, and Fehniger, Todd A., primary

Published
2023
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38. Supplementary Tables from Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations with Response after Adoptive Immunotherapy for Leukemia

Author

Berrien-Elliott, Melissa M., primary, Cashen, Amanda F., primary, Cubitt, Celia C., primary, Neal, Carly C., primary, Wong, Pamela, primary, Wagner, Julia A., primary, Foster, Mark, primary, Schappe, Timothy, primary, Desai, Sweta, primary, McClain, Ethan, primary, Becker-Hapak, Michelle, primary, Foltz, Jennifer A., primary, Cooper, Matthew L., primary, Jaeger, Natalia, primary, Srivatsan, Sridhar Nonavinkere, primary, Gao, Feng, primary, Romee, Rizwan, primary, Abboud, Camille N., primary, Uy, Geoffrey L., primary, Westervelt, Peter, primary, Jacoby, Meagan A., primary, Pusic, Iskra, primary, Stockerl-Goldstein, Keith E., primary, Schroeder, Mark A., primary, DiPersio, John, primary, and Fehniger, Todd A., primary

Published
2023
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41. Supplementary Methods from Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations with Response after Adoptive Immunotherapy for Leukemia

Author

Berrien-Elliott, Melissa M., primary, Cashen, Amanda F., primary, Cubitt, Celia C., primary, Neal, Carly C., primary, Wong, Pamela, primary, Wagner, Julia A., primary, Foster, Mark, primary, Schappe, Timothy, primary, Desai, Sweta, primary, McClain, Ethan, primary, Becker-Hapak, Michelle, primary, Foltz, Jennifer A., primary, Cooper, Matthew L., primary, Jaeger, Natalia, primary, Srivatsan, Sridhar Nonavinkere, primary, Gao, Feng, primary, Romee, Rizwan, primary, Abboud, Camille N., primary, Uy, Geoffrey L., primary, Westervelt, Peter, primary, Jacoby, Meagan A., primary, Pusic, Iskra, primary, Stockerl-Goldstein, Keith E., primary, Schroeder, Mark A., primary, DiPersio, John, primary, and Fehniger, Todd A., primary

Published
2023
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45. Supplementary Figures from Multidimensional Analyses of Donor Memory-Like NK Cells Reveal New Associations with Response after Adoptive Immunotherapy for Leukemia

Author

Berrien-Elliott, Melissa M., primary, Cashen, Amanda F., primary, Cubitt, Celia C., primary, Neal, Carly C., primary, Wong, Pamela, primary, Wagner, Julia A., primary, Foster, Mark, primary, Schappe, Timothy, primary, Desai, Sweta, primary, McClain, Ethan, primary, Becker-Hapak, Michelle, primary, Foltz, Jennifer A., primary, Cooper, Matthew L., primary, Jaeger, Natalia, primary, Srivatsan, Sridhar Nonavinkere, primary, Gao, Feng, primary, Romee, Rizwan, primary, Abboud, Camille N., primary, Uy, Geoffrey L., primary, Westervelt, Peter, primary, Jacoby, Meagan A., primary, Pusic, Iskra, primary, Stockerl-Goldstein, Keith E., primary, Schroeder, Mark A., primary, DiPersio, John, primary, and Fehniger, Todd A., primary

Published
2023
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46. Supplementary Figure S4 from Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood–Derived NK Cells Facilitates CAR-like Responses Against CD30+ Malignancies

Author

Kerbauy, Lucila N., primary, Marin, Nancy D., primary, Kaplan, Mecit, primary, Banerjee, Pinaki P., primary, Berrien-Elliott, Melissa M., primary, Becker-Hapak, Michelle, primary, Basar, Rafet, primary, Foster, Mark, primary, Garcia Melo, Luciana, primary, Neal, Carly C., primary, McClain, Ethan, primary, Daher, May, primary, Nunez Cortes, Ana Karen, primary, Desai, Sweta, primary, Inng Lim, Francesca Wei, primary, Mendt, Mayela Carolina, primary, Schappe, Timothy, primary, Li, Li, primary, Shaim, Hila, primary, Shanley, Mayra, primary, Ensley, Emily L., primary, Uprety, Nadima, primary, Wong, Pamela, primary, Liu, Enli, primary, Ang, Sonny O., primary, Cai, Rong, primary, Nandivada, Vandana, primary, Mohanty, Vakul, primary, Miao, Qi, primary, Shen, Yifei, primary, Baran, Natalia, primary, Fowlkes, Natalie W., primary, Chen, Ken, primary, Muniz-Feliciano, Luis, primary, Champlin, Richard E., primary, Nieto, Yago L., primary, Koch, Joachim, primary, Treder, Martin, primary, Fischer, Wolfgang, primary, Okamoto, Oswaldo Keith, primary, Shpall, Elizabeth J., primary, Fehniger, Todd A., primary, and Rezvani, Katayoun, primary

Published
2023
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47. Table S1 from Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma

Author

Foltz, Jennifer A., primary, Hess, Brian T., primary, Bachanova, Veronika, primary, Bartlett, Nancy L., primary, Berrien-Elliott, Melissa M., primary, McClain, Ethan, primary, Becker-Hapak, Michelle, primary, Foster, Mark, primary, Schappe, Timothy, primary, Kahl, Brad, primary, Mehta-Shah, Neha, primary, Cashen, Amanda F., primary, Marin, Nancy D., primary, McDaniels, Kristen, primary, Moreno, Chaz, primary, Mosior, Matthew, primary, Gao, Feng, primary, Griffith, Obi L., primary, Griffith, Malachi, primary, Wagner, Julia A., primary, Epperla, Narendranath, primary, Rock, Amy D., primary, Lee, John, primary, Petti, Allegra A., primary, Soon-Shiong, Patrick, primary, and Fehniger, Todd A., primary

Published
2023
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48. Supplementary Table S2 from Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood–Derived NK Cells Facilitates CAR-like Responses Against CD30+ Malignancies

Author

Kerbauy, Lucila N., primary, Marin, Nancy D., primary, Kaplan, Mecit, primary, Banerjee, Pinaki P., primary, Berrien-Elliott, Melissa M., primary, Becker-Hapak, Michelle, primary, Basar, Rafet, primary, Foster, Mark, primary, Garcia Melo, Luciana, primary, Neal, Carly C., primary, McClain, Ethan, primary, Daher, May, primary, Nunez Cortes, Ana Karen, primary, Desai, Sweta, primary, Inng Lim, Francesca Wei, primary, Mendt, Mayela Carolina, primary, Schappe, Timothy, primary, Li, Li, primary, Shaim, Hila, primary, Shanley, Mayra, primary, Ensley, Emily L., primary, Uprety, Nadima, primary, Wong, Pamela, primary, Liu, Enli, primary, Ang, Sonny O., primary, Cai, Rong, primary, Nandivada, Vandana, primary, Mohanty, Vakul, primary, Miao, Qi, primary, Shen, Yifei, primary, Baran, Natalia, primary, Fowlkes, Natalie W., primary, Chen, Ken, primary, Muniz-Feliciano, Luis, primary, Champlin, Richard E., primary, Nieto, Yago L., primary, Koch, Joachim, primary, Treder, Martin, primary, Fischer, Wolfgang, primary, Okamoto, Oswaldo Keith, primary, Shpall, Elizabeth J., primary, Fehniger, Todd A., primary, and Rezvani, Katayoun, primary

Published
2023
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49. Figure S3 from Phase I Trial of N-803, an IL15 Receptor Agonist, with Rituximab in Patients with Indolent Non-Hodgkin Lymphoma

Author

Foltz, Jennifer A., primary, Hess, Brian T., primary, Bachanova, Veronika, primary, Bartlett, Nancy L., primary, Berrien-Elliott, Melissa M., primary, McClain, Ethan, primary, Becker-Hapak, Michelle, primary, Foster, Mark, primary, Schappe, Timothy, primary, Kahl, Brad, primary, Mehta-Shah, Neha, primary, Cashen, Amanda F., primary, Marin, Nancy D., primary, McDaniels, Kristen, primary, Moreno, Chaz, primary, Mosior, Matthew, primary, Gao, Feng, primary, Griffith, Obi L., primary, Griffith, Malachi, primary, Wagner, Julia A., primary, Epperla, Narendranath, primary, Rock, Amy D., primary, Lee, John, primary, Petti, Allegra A., primary, Soon-Shiong, Patrick, primary, and Fehniger, Todd A., primary

Published
2023
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50. Data from MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis

Author

Trissal, Maria C., primary, Wong, Terrence N., primary, Yao, Juo-Chin, primary, Ramaswamy, Rahul, primary, Kuo, Iris, primary, Baty, Jack, primary, Sun, Yaping, primary, Jih, Gloria, primary, Parikh, Nishi, primary, Berrien-Elliott, Melissa M., primary, Fehniger, Todd A., primary, Ley, Timothy J., primary, Maillard, Ivan, primary, Reddy, Pavan R., primary, and Link, Daniel C., primary

Published
2023
Full Text
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