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3. The history of Coast Salish woolly dogs revealed by ancient genomics and Indigenous Knowledge.

Author

Lin, Audrey, Hammond-Kaarremaa, Liz, Liu, Hsiao-Lei, Stantis, Chris, McKechnie, Iain, Pavel, Michael, Pavel, Susan, Wyss, Senaqwila, Sparrow, Debra, Carr, Karen, Aninta, Sabhrina, Perri, Angela, Hartt, Jonathan, Bergström, Anders, Carmagnini, Alberto, Charlton, Sophy, Dalén, Love, Feuerborn, Tatiana, France, Christine, Gopalakrishnan, Shyam, Grimes, Vaughan, Harris, Alex, Kavich, Gwénaëlle, Sinding, Mikkel-Holger, Skoglund, Pontus, Stanton, David, Ostrander, Elaine, Larson, Greger, Armstrong, Chelsey, Frantz, Laurent, Hawkins, Melissa, Kistler, Logan, and Sacks, Benjamin

Subjects
Animals, Dogs, Genomics, Northwestern United States, Breeding, Wool, Selection, Genetic
Abstract

Ancestral Coast Salish societies in the Pacific Northwest kept long-haired woolly dogs that were bred and cared for over millennia. However, the dog wool-weaving tradition declined during the 19th century, and the population was lost. In this study, we analyzed genomic and isotopic data from a preserved woolly dog pelt from Mutton, collected in 1859. Mutton is the only known example of an Indigenous North American dog with dominant precolonial ancestry postdating the onset of settler colonialism. We identified candidate genetic variants potentially linked with their distinct woolly phenotype. We integrated these data with interviews from Coast Salish Elders, Knowledge Keepers, and weavers about shared traditional knowledge and memories surrounding woolly dogs, their importance within Coast Salish societies, and how colonial policies led directly to their disappearance.

Published
2023

5. Grey wolf genomic history reveals a dual ancestry of dogs

Author

Bergström, Anders, Stanton, David WG, Taron, Ulrike H, Frantz, Laurent, Sinding, Mikkel-Holger S, Ersmark, Erik, Pfrengle, Saskia, Cassatt-Johnstone, Molly, Lebrasseur, Ophélie, Girdland-Flink, Linus, Fernandes, Daniel M, Ollivier, Morgane, Speidel, Leo, Gopalakrishnan, Shyam, Westbury, Michael V, Ramos-Madrigal, Jazmin, Feuerborn, Tatiana R, Reiter, Ella, Gretzinger, Joscha, Münzel, Susanne C, Swali, Pooja, Conard, Nicholas J, Carøe, Christian, Haile, James, Linderholm, Anna, Androsov, Semyon, Barnes, Ian, Baumann, Chris, Benecke, Norbert, Bocherens, Hervé, Brace, Selina, Carden, Ruth F, Drucker, Dorothée G, Fedorov, Sergey, Gasparik, Mihály, Germonpré, Mietje, Grigoriev, Semyon, Groves, Pam, Hertwig, Stefan T, Ivanova, Varvara V, Janssens, Luc, Jennings, Richard P, Kasparov, Aleksei K, Kirillova, Irina V, Kurmaniyazov, Islam, Kuzmin, Yaroslav V, Kosintsev, Pavel A, Lázničková-Galetová, Martina, Leduc, Charlotte, Nikolskiy, Pavel, Nussbaumer, Marc, O’Drisceoil, Cóilín, Orlando, Ludovic, Outram, Alan, Pavlova, Elena Y, Perri, Angela R, Pilot, Małgorzata, Pitulko, Vladimir V, Plotnikov, Valerii V, Protopopov, Albert V, Rehazek, André, Sablin, Mikhail, Seguin-Orlando, Andaine, Storå, Jan, Verjux, Christian, Zaibert, Victor F, Zazula, Grant, Crombé, Philippe, Hansen, Anders J, Willerslev, Eske, Leonard, Jennifer A, Götherström, Anders, Pinhasi, Ron, Schuenemann, Verena J, Hofreiter, Michael, Gilbert, M Thomas P, Shapiro, Beth, Larson, Greger, Krause, Johannes, Dalén, Love, and Skoglund, Pontus

Subjects
Africa, Animals, DNA, Ancient, Dogs, Domestication, Europe, Genome, Genomics, History, Ancient, Middle East, Mutation, North America, Phylogeny, Selection, Genetic, Siberia, Tumor Suppressor Proteins, Wolves, General Science & Technology
Abstract

The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and they remained widespread throughout the last Ice Age when many other large mammal species went extinct. Little is known, however, about the history and possible extinction of past wolf populations or when and where the wolf progenitors of the present-day dog lineage (Canis familiaris) lived1-8. Here we analysed 72 ancient wolf genomes spanning the last 100,000 years from Europe, Siberia and North America. We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today. This population connectivity allowed us to detect natural selection across the time series, including rapid fixation of mutations in the gene IFT88 40,000-30,000 years ago. We show that dogs are overall more closely related to ancient wolves from eastern Eurasia than to those from western Eurasia, suggesting a domestication process in the east. However, we also found that dogs in the Near East and Africa derive up to half of their ancestry from a distinct population related to modern southwest Eurasian wolves, reflecting either an independent domestication process or admixture from local wolves. None of the analysed ancient wolf genomes is a direct match for either of these dog ancestries, meaning that the exact progenitor populations remain to be located.

Published
2022

6. Yersinia pestis genomes reveal plague in Britain 4000 years ago

Author

Swali, Pooja, Schulting, Rick, Gilardet, Alexandre, Kelly, Monica, Anastasiadou, Kyriaki, Glocke, Isabelle, McCabe, Jesse, Williams, Mia, Audsley, Tony, Loe, Louise, Fernández-Crespo, Teresa, Ordoño, Javier, Walker, David, Clare, Tom, Cook, Geoff, Hodkinson, Ian, Simpson, Mark, Read, Stephen, Davy, Tom, Silva, Marina, Hajdinjak, Mateja, Bergström, Anders, Booth, Thomas, and Skoglund, Pontus

Published
2023
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7. Million-year-old DNA sheds light on the genomic history of mammoths

Author

van der Valk, Tom, Pečnerová, Patrícia, Díez-del-Molino, David, Bergström, Anders, Oppenheimer, Jonas, Hartmann, Stefanie, Xenikoudakis, Georgios, Thomas, Jessica A, Dehasque, Marianne, Sağlıcan, Ekin, Fidan, Fatma Rabia, Barnes, Ian, Liu, Shanlin, Somel, Mehmet, Heintzman, Peter D, Nikolskiy, Pavel, Shapiro, Beth, Skoglund, Pontus, Hofreiter, Michael, Lister, Adrian M, Götherström, Anders, and Dalén, Love

Subjects
Genetics, Human Genome, Biotechnology, Acclimatization, Alleles, Animals, Bayes Theorem, DNA, Ancient, Elephants, Europe, Evolution, Molecular, Female, Fossils, Genetic Variation, Genome, Mitochondrial, Genomics, Mammoths, Markov Chains, Molar, North America, Phylogeny, Radiometric Dating, Siberia, Time Factors, General Science & Technology
Abstract

Temporal genomic data hold great potential for studying evolutionary processes such as speciation. However, sampling across speciation events would, in many cases, require genomic time series that stretch well back into the Early Pleistocene subepoch. Although theoretical models suggest that DNA should survive on this timescale1, the oldest genomic data recovered so far are from a horse specimen dated to 780-560 thousand years ago2. Here we report the recovery of genome-wide data from three mammoth specimens dating to the Early and Middle Pleistocene subepochs, two of which are more than one million years old. We find that two distinct mammoth lineages were present in eastern Siberia during the Early Pleistocene. One of these lineages gave rise to the woolly mammoth and the other represents a previously unrecognized lineage that was ancestral to the first mammoths to colonize North America. Our analyses reveal that the Columbian mammoth of North America traces its ancestry to a Middle Pleistocene hybridization between these two lineages, with roughly equal admixture proportions. Finally, we show that the majority of protein-coding changes associated with cold adaptation in woolly mammoths were already present one million years ago. These findings highlight the potential of deep-time palaeogenomics to expand our understanding of speciation and long-term adaptive evolution.

Published
2021

9. Archaeological Central American maize genomes suggest ancient gene flow from South America.

Author

Kistler, Logan, Thakar, Heather, VanDerwarker, Amber, Domic, Alejandra, Bergström, Anders, George, Richard, Harper, Thomas, Allaby, Robin, Hirth, Kenneth, and Kennett, Douglas

Subjects
agriculture, ancient DNA, archaeogenomics, domestication, maize, Central America, Evolution, Molecular, Gene Flow, Genome, Plant, Hybridization, Genetic, Plant Breeding, South America, Zea mays
Abstract

Maize (Zea mays ssp. mays) domestication began in southwestern Mexico ∼9,000 calendar years before present (cal. BP) and humans dispersed this important grain to South America by at least 7,000 cal. BP as a partial domesticate. South America served as a secondary improvement center where the domestication syndrome became fixed and new lineages emerged in parallel with similar processes in Mesoamerica. Later, Indigenous cultivators carried a second major wave of maize southward from Mesoamerica, but it has been unclear until now whether the deeply divergent maize lineages underwent any subsequent gene flow between these regions. Here we report ancient maize genomes (2,300-1,900 cal. BP) from El Gigante rock shelter, Honduras, that are closely related to ancient and modern maize from South America. Our findings suggest that the second wave of maize brought into South America hybridized with long-established landraces from the first wave, and that some of the resulting newly admixed lineages were then reintroduced to Central America. Direct radiocarbon dates and cob morphological data from the rock shelter suggest that more productive maize varieties developed between 4,300 and 2,500 cal. BP. We hypothesize that the influx of maize from South America into Central America may have been an important source of genetic diversity as maize was becoming a staple grain in Central and Mesoamerica.

Published
2020

11. Genomic insights into the human population history of Australia and New Guinea

Author

Bergström, Anders and Tyler-Smith, Chris

Subjects
569.9, Human genetics, Population genomics, Genome sequencing, Population history
Abstract

The ancient continent of Sahul, encompassing Australia, New Guinea and Tasmania, contains some of the earliest archaeological evidence for humans outside of Africa, dating back to at least 50 thousand years ago (kya). New Guinea was also one of the sites were humans developed agriculture in the last 10 thousand years. Despite the importance of this part of the world to the history of humanity outside Africa, little is known about the population history of the people living here. In this thesis I present population-genetic studies using whole-genome sequencing and genotype array datasets from more than 500 indigenous individuals from Australia and New Guinea, as well as initial work on large-scale sequencing of other, worldwide, human populations in the Human Genome Diversity Project panel. Other than recent admixture after European colonization of Australia, and Southeast Asian ad- mixture in the lowlands of New Guinea in the last few millennia, the populations of Sahul appear to have been genetically independent from the rest of the world since their divergence ∼50 kya. There is no evidence for South Asian gene flow to Australia, as previously suggested, and the highlands of Papua New Guinea (PNG) have remained unaffected by non-New Guinean gene flow until the present day. Despite Sahul being a single connected landmass until ∼8 kya, different groups across Australia are nearly equally related to Papuans, and vice versa, and the two appear to have separated genetically already ∼30 kya. In PNG, all highlanders strikingly appear to form a clade relative to lowlanders, and population structure seems to have been reshaped, with major population size increases, on the same timescale as the spread of agriculture. However, present- day genetic differentiation between groups is much stronger in PNG than in other parts of the world that have also transitioned to agriculture, demonstrating that such a lifestyle change does not necessarily lead to genetic homogenization. The results presented here provide detailed insights into the population history of Sahul, and sug- gests that its history can serve as an independent source of evidence for understanding human evolutionary trajectories, including the relationships between genetics, lifestyle, languages and culture.

Published
2018
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12. Genome-scale sequencing and analysis of human, wolf, and bison DNA from 25,000-year-old sediment

Author

Gelabert, Pere, Sawyer, Susanna, Bergström, Anders, Margaryan, Ashot, Collin, Thomas C., Meshveliani, Tengiz, Belfer-Cohen, Anna, Lordkipanidze, David, Jakeli, Nino, Matskevich, Zinovi, Bar-Oz, Guy, Fernandes, Daniel M., Cheronet, Olivia, Özdoğan, Kadir T., Oberreiter, Victoria, Feeney, Robin N.M., Stahlschmidt, Mareike C., Skoglund, Pontus, and Pinhasi, Ron

Published
2021
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14. Origins of modern human ancestry

Author

Bergström, Anders, Stringer, Chris, Hajdinjak, Mateja, Scerri, Eleanor M. L., and Skoglund, Pontus

Subjects
Anthropological research, Human evolution -- Research, Paleoanthropology -- Research, Human beings -- Origin, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

New finds in the palaeoanthropological and genomic records have changed our view of the origins of modern human ancestry. Here we review our current understanding of how the ancestry of modern humans around the globe can be traced into the deep past, and which ancestors it passes through during our journey back in time. We identify three key phases that are surrounded by major questions, and which will be at the frontiers of future research. The most recent phase comprises the worldwide expansion of modern humans between 40 and 60 thousand years ago (ka) and their last known contacts with archaic groups such as Neanderthals and Denisovans. The second phase is associated with a broadly construed African origin of modern human diversity between 60 and 300 ka. The oldest phase comprises the complex separation of modern human ancestors from archaic human groups from 0.3 to 1 million years ago. We argue that no specific point in time can currently be identified at which modern human ancestry was confined to a limited birthplace, and that patterns of the first appearance of anatomical or behavioural traits that are used to define Homo sapiens are consistent with a range of evolutionary histories. A Review describes the three key phases that define the origins of modern human ancestry, and highlights the importance of analysing both palaeoanthropological and genomic records to further improve our understanding of our evolutionary history., Author(s): Anders Bergström [sup.1] , Chris Stringer [sup.2] , Mateja Hajdinjak [sup.1] , Eleanor M. L. Scerri [sup.3] [sup.4] [sup.5] , Pontus Skoglund [sup.1] Author Affiliations: (1) Ancient Genomics Laboratory, [...]

Published
2021
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16. A genomic history of Aboriginal Australia

Author

Malaspinas, Anna-Sapfo, Westaway, Michael C, Muller, Craig, Sousa, Vitor C, Lao, Oscar, Alves, Isabel, Bergström, Anders, Athanasiadis, Georgios, Cheng, Jade Y, Crawford, Jacob E, Heupink, Tim H, Macholdt, Enrico, Peischl, Stephan, Rasmussen, Simon, Schiffels, Stephan, Subramanian, Sankar, Wright, Joanne L, Albrechtsen, Anders, Barbieri, Chiara, Dupanloup, Isabelle, Eriksson, Anders, Margaryan, Ashot, Moltke, Ida, Pugach, Irina, Korneliussen, Thorfinn S, Levkivskyi, Ivan P, Moreno-Mayar, J Víctor, Ni, Shengyu, Racimo, Fernando, Sikora, Martin, Xue, Yali, Aghakhanian, Farhang A, Brucato, Nicolas, Brunak, Søren, Campos, Paula F, Clark, Warren, Ellingvåg, Sturla, Fourmile, Gudjugudju, Gerbault, Pascale, Injie, Darren, Koki, George, Leavesley, Matthew, Logan, Betty, Lynch, Aubrey, Matisoo-Smith, Elizabeth A, McAllister, Peter J, Mentzer, Alexander J, Metspalu, Mait, Migliano, Andrea B, Murgha, Les, Phipps, Maude E, Pomat, William, Reynolds, Doc, Ricaut, Francois-Xavier, Siba, Peter, Thomas, Mark G, Wales, Thomas, Wall, Colleen Ma’run, Oppenheimer, Stephen J, Tyler-Smith, Chris, Durbin, Richard, Dortch, Joe, Manica, Andrea, Schierup, Mikkel H, Foley, Robert A, Lahr, Marta Mirazón, Bowern, Claire, Wall, Jeffrey D, Mailund, Thomas, Stoneking, Mark, Nielsen, Rasmus, Sandhu, Manjinder S, Excoffier, Laurent, Lambert, David M, and Willerslev, Eske

Subjects
Africa, Australia, Datasets as Topic, Desert Climate, Gene Flow, Genetics, Population, Genome, Human, Genomics, History, Ancient, Human Migration, Humans, Language, Native Hawaiian or Other Pacific Islander, New Guinea, Phylogeny, Population Dynamics, Racial Groups, Tasmania, General Science & Technology
Abstract

The population history of Aboriginal Australians remains largely uncharacterized. Here we generate high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25-40 thousand years ago (kya), suggesting pre-Holocene population structure in the ancient continent of Sahul (Australia, New Guinea and Tasmania). However, all of the studied Aboriginal Australians descend from a single founding population that differentiated ~10-32 kya. We infer a population expansion in northeast Australia during the Holocene epoch (past 10,000 years) associated with limited gene flow from this region to the rest of Australia, consistent with the spread of the Pama-Nyungan languages. We estimate that Aboriginal Australians and Papuans diverged from Eurasians 51-72 kya, following a single out-of-Africa dispersal, and subsequently admixed with archaic populations. Finally, we report evidence of selection in Aboriginal Australians potentially associated with living in the desert.

Published
2016

19. Recovering the Historical Construction and Materials of Erik Gunnar Asplund’s Stockholm Public Library

Author

Fleming, Patrick, Mill, Petronella, Rovira Torres, Marcelo, Bergström, Anders, Fleming, Patrick, Mill, Petronella, Rovira Torres, Marcelo, and Bergström, Anders

Abstract

This work presents the first detailed study of the construction and materials of the Stockholm Public Library. As the building undergoes a rare period of maintenance and renovation, the floors and walls of the library are examined from three perspectives. First, using available but limited archival documents and plans; second, with non-destructive ground-penetrating radar measurements; and finally, through on-site surveys during local interventions for the maintenance and renovation process. The ensuing results emphasize the complementary nature of this combined research approach in recovering lost or forgotten construction details and further reveal several important findings. In the case of the unique wall finishing of the library’s rotunda, multiple layers of lime mortar, each varying in thickness and coarseness, were used to build up and craft the relief-like interior wall surface. With the use of in-situ aerated concrete and prefabricated Solomite panels in the library’s 1931–32 floor construction, a material connection between Asplund and the broader modern movement in architecture is further highlighted. At first glance, these construction-related findings seem to reinforce the common architectural narrative of the library as a transitional project between neoclassicism and modernism. At the same time, however, the library’s separate periods of construction of 1925–28 and 1931–32 and their distinct materials can be seen as a continuity of construction culture, with the innovative use of local raw materials related to the Swedish landscape., QC 20240724, This research was supported by the Swiss National Science Foundation through an Ambizione Research Grant (Project 193356)

Published
2024
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20. Genomic evidence for the Pleistocene and recent population history of Native Americans

Author

Raghavan, Maanasa, Steinrücken, Matthias, Harris, Kelley, Schiffels, Stephan, Rasmussen, Simon, DeGiorgio, Michael, Albrechtsen, Anders, Valdiosera, Cristina, Ávila-Arcos, María C, Malaspinas, Anna-Sapfo, Eriksson, Anders, Moltke, Ida, Metspalu, Mait, Homburger, Julian R, Wall, Jeff, Cornejo, Omar E, Moreno-Mayar, J Víctor, Korneliussen, Thorfinn S, Pierre, Tracey, Rasmussen, Morten, Campos, Paula F, de Barros Damgaard, Peter, Allentoft, Morten E, Lindo, John, Metspalu, Ene, Rodríguez-Varela, Ricardo, Mansilla, Josefina, Henrickson, Celeste, Seguin-Orlando, Andaine, Malmström, Helena, Stafford, Thomas, Shringarpure, Suyash S, Moreno-Estrada, Andrés, Karmin, Monika, Tambets, Kristiina, Bergström, Anders, Xue, Yali, Warmuth, Vera, Friend, Andrew D, Singarayer, Joy, Valdes, Paul, Balloux, Francois, Leboreiro, Ilán, Vera, Jose Luis, Rangel-Villalobos, Hector, Pettener, Davide, Luiselli, Donata, Davis, Loren G, Heyer, Evelyne, Zollikofer, Christoph PE, Ponce de León, Marcia S, Smith, Colin I, Grimes, Vaughan, Pike, Kelly-Anne, Deal, Michael, Fuller, Benjamin T, Arriaza, Bernardo, Standen, Vivien, Luz, Maria F, Ricaut, Francois, Guidon, Niede, Osipova, Ludmila, Voevoda, Mikhail I, Posukh, Olga L, Balanovsky, Oleg, Lavryashina, Maria, Bogunov, Yuri, Khusnutdinova, Elza, Gubina, Marina, Balanovska, Elena, Fedorova, Sardana, Litvinov, Sergey, Malyarchuk, Boris, Derenko, Miroslava, Mosher, MJ, Archer, David, Cybulski, Jerome, Petzelt, Barbara, Mitchell, Joycelynn, Worl, Rosita, Norman, Paul J, Parham, Peter, Kemp, Brian M, Kivisild, Toomas, Tyler-Smith, Chris, Sandhu, Manjinder S, Crawford, Michael, Villems, Richard, Smith, David Glenn, Waters, Michael R, Goebel, Ted, Johnson, John R, Malhi, Ripan S, Jakobsson, Mattias, Meltzer, David J, Manica, Andrea, Durbin, Richard, Bustamante, Carlos D, Song, Yun S, and Nielsen, Rasmus

Subjects
Biological Sciences, Genetics, History, Heritage and Archaeology, Human Society, Historical Studies, Anthropology, Minority Health, Human Genome, American Indian or Alaska Native, Americas, Gene Flow, Genomics, History, Ancient, Human Migration, Humans, Indians, North American, Models, Genetic, Siberia, General Science & Technology
Abstract

How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.

Published
2015

21. POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.

Author

Raghavan, Maanasa, Steinrücken, Matthias, Harris, Kelley, Schiffels, Stephan, Rasmussen, Simon, DeGiorgio, Michael, Albrechtsen, Anders, Valdiosera, Cristina, Ávila-Arcos, María C, Malaspinas, Anna-Sapfo, Eriksson, Anders, Moltke, Ida, Metspalu, Mait, Homburger, Julian R, Wall, Jeff, Cornejo, Omar E, Moreno-Mayar, J Víctor, Korneliussen, Thorfinn S, Pierre, Tracey, Rasmussen, Morten, Campos, Paula F, de Barros Damgaard, Peter, Allentoft, Morten E, Lindo, John, Metspalu, Ene, Rodríguez-Varela, Ricardo, Mansilla, Josefina, Henrickson, Celeste, Seguin-Orlando, Andaine, Malmström, Helena, Stafford, Thomas, Shringarpure, Suyash S, Moreno-Estrada, Andrés, Karmin, Monika, Tambets, Kristiina, Bergström, Anders, Xue, Yali, Warmuth, Vera, Friend, Andrew D, Singarayer, Joy, Valdes, Paul, Balloux, Francois, Leboreiro, Ilán, Vera, Jose Luis, Rangel-Villalobos, Hector, Pettener, Davide, Luiselli, Donata, Davis, Loren G, Heyer, Evelyne, Zollikofer, Christoph PE, Ponce de León, Marcia S, Smith, Colin I, Grimes, Vaughan, Pike, Kelly-Anne, Deal, Michael, Fuller, Benjamin T, Arriaza, Bernardo, Standen, Vivien, Luz, Maria F, Ricaut, Francois, Guidon, Niede, Osipova, Ludmila, Voevoda, Mikhail I, Posukh, Olga L, Balanovsky, Oleg, Lavryashina, Maria, Bogunov, Yuri, Khusnutdinova, Elza, Gubina, Marina, Balanovska, Elena, Fedorova, Sardana, Litvinov, Sergey, Malyarchuk, Boris, Derenko, Miroslava, Mosher, MJ, Archer, David, Cybulski, Jerome, Petzelt, Barbara, Mitchell, Joycelynn, Worl, Rosita, Norman, Paul J, Parham, Peter, Kemp, Brian M, Kivisild, Toomas, Tyler-Smith, Chris, Sandhu, Manjinder S, Crawford, Michael, Villems, Richard, Smith, David Glenn, Waters, Michael R, Goebel, Ted, Johnson, John R, Malhi, Ripan S, Jakobsson, Mattias, Meltzer, David J, Manica, Andrea, Durbin, Richard, Bustamante, Carlos D, Song, Yun S, and Nielsen, Rasmus

Subjects
Humans, Genomics, Models, Genetic, History, Ancient, Indians, North American, Americas, Siberia, Gene Flow, Human Migration, Human Genome, Genetics, General Science & Technology
Abstract

How and when the Americas were populated remains contentious. Using ancient and modern genome-wide data, we found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians, entered the Americas as a single migration wave from Siberia no earlier than 23 thousand years ago (ka) and after no more than an 8000-year isolation period in Beringia. After their arrival to the Americas, ancestral Native Americans diversified into two basal genetic branches around 13 ka, one that is now dispersed across North and South America and the other restricted to North America. Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East Asians (including Siberians) and, more distantly, Australo-Melanesians. Putative "Paleoamerican" relict populations, including the historical Mexican Pericúes and South American Fuego-Patagonians, are not directly related to modern Australo-Melanesians as suggested by the Paleoamerican Model.

Published
2015

23. Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa

Author

Gurdasani, Deepti, Carstensen, Tommy, Fatumo, Segun, Chen, Guanjie, Franklin, Chris S., Prado-Martinez, Javier, Bouman, Heleen, Abascal, Federico, Haber, Marc, Tachmazidou, Ioanna, Mathieson, Iain, Ekoru, Kenneth, DeGorter, Marianne K., Nsubuga, Rebecca N., Finan, Chris, Wheeler, Eleanor, Chen, Li, Cooper, David N., Schiffels, Stephan, Chen, Yuan, Ritchie, Graham R.S., Pollard, Martin O., Fortune, Mary D., Mentzer, Alex J., Garrison, Erik, Bergström, Anders, Hatzikotoulas, Konstantinos, Adeyemo, Adebowale, Doumatey, Ayo, Elding, Heather, Wain, Louise V., Ehret, Georg, Auer, Paul L., Kooperberg, Charles L., Reiner, Alexander P., Franceschini, Nora, Maher, Dermot, Montgomery, Stephen B., Kadie, Carl, Widmer, Chris, Xue, Yali, Seeley, Janet, Asiki, Gershim, Kamali, Anatoli, Young, Elizabeth H., Pomilla, Cristina, Soranzo, Nicole, Zeggini, Eleftheria, Pirie, Fraser, Morris, Andrew P., Heckerman, David, Tyler-Smith, Chris, Motala, Ayesha A., Rotimi, Charles, Kaleebu, Pontiano, Barroso, Inês, and Sandhu, Manj S.

Published
2019
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24. Guidelines for the management of open‐angle glaucoma

Author

Jóhannesson, Gauti, primary, Stille, Ulf, additional, Taube, Amelie Botling, additional, Karlsson, Markus, additional, Kalaboukhova, Lada, additional, Bergström, Anders, additional, Peters, Dorothea, additional, and Lindén, Christina, additional

Published
2024
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33. Genome evolution across 1,011 Saccharomyces cerevisiae isolates

Author

Peter, Jackson, De Chiara, Matteo, Friedrich, Anne, Yue, Jia-Xing, Pflieger, David, Bergström, Anders, Sigwalt, Anastasie, Barre, Benjamin, Freel, Kelle, Llored, Agnès, Cruaud, Corinne, Labadie, Karine, Aury, Jean-Marc, Istace, Benjamin, Lebrigand, Kevin, Barbry, Pascal, Engelen, Stefan, Lemainque, Arnaud, Wincker, Patrick, Liti, Gianni, and Schacherer, Joseph

Published
2018
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38. Archival Plans, Alterations, and 3D Laser Scanning of Erik Gunnar Asplund’s Stockholm Public Library

Author

Fleming, Patrick H., Bergström, Anders, Fleming, Patrick H., and Bergström, Anders

Abstract

Erik Gunnar Asplund’s Stockholm Public Library is considered an important building in the history of twentieth-century architecture, yet relatively few archival plans have been saved from the library’s extended design process from 1919–25 and its subsequent construction until opening in 1928. This work presents the first systematic review of the available, digitised archival plans from Sweden’s National Centre for Architecture and Design (ArkDes), and explains Asplund’s gradual design and development of the project. Subsequent alterations in the library are briefly summarised, followed by the results from an extensive 3D laser scanning process throughout and around the building as it undergoes a significant period of renovation and maintenance. The results from 3D laser scanning create the first comprehensive and detailed record of the building for supporting future research, teaching, and renovation work. This study emphasises the mutual benefits of combining historical and technological approaches, and conducting academic research in parallel with contemporary renovation projects of historical architecture., QC 20240703, This research was supported by the Swiss National Science Foundation through an Ambizione Research Grant (Project 193356)

Published
2023
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39. The history of Coast Salish 'woolly dogs' revealed by ancient genomics and Indigenous Knowledge

Author

Lin, Audrey T., Hammond-Kaarremaa, Liz, Liu, Hsiao-Lei, Stantis, Chris, McKechnie, Iain, Pavel, Michael, Pavel, Susan Sa'hLa MitSa, Wyss, Senaqwila Sen̓áḵw, Sparrow, Debra Qwasen, Carr, Karen, Aninta, Sabhrina Gita, Perri, Angela, Hartt, Jonathan, Bergström, Anders, Carmagnini, Alberto, Charlton, Sophy, Dalén, Love, Feuerborn, Tatiana R., France, Christine A. M., Gopalakrishnan, Shyam, Grimes, Vaughan, Harris, Alex, Kavich, Gwénaëlle, Sacks, Benjamin N., Sinding, Mikkel-Holger S., Skoglund, Pontus, Stanton, David W. G., Ostrander, Elaine A., Larson, Greger, Armstrong, Chelsey G., Frantz, Laurent A. F., Hawkins, Melissa T. R., Kistler, Logan, Lin, Audrey T., Hammond-Kaarremaa, Liz, Liu, Hsiao-Lei, Stantis, Chris, McKechnie, Iain, Pavel, Michael, Pavel, Susan Sa'hLa MitSa, Wyss, Senaqwila Sen̓áḵw, Sparrow, Debra Qwasen, Carr, Karen, Aninta, Sabhrina Gita, Perri, Angela, Hartt, Jonathan, Bergström, Anders, Carmagnini, Alberto, Charlton, Sophy, Dalén, Love, Feuerborn, Tatiana R., France, Christine A. M., Gopalakrishnan, Shyam, Grimes, Vaughan, Harris, Alex, Kavich, Gwénaëlle, Sacks, Benjamin N., Sinding, Mikkel-Holger S., Skoglund, Pontus, Stanton, David W. G., Ostrander, Elaine A., Larson, Greger, Armstrong, Chelsey G., Frantz, Laurent A. F., Hawkins, Melissa T. R., and Kistler, Logan

Abstract

Ancestral Coast Salish societies in the Pacific Northwest kept long-haired woolly dogs that were bred and cared for over millennia. However, the dog wool-weaving tradition declined during the 19th century, and the population was lost. In this study, we analyzed genomic and isotopic data from a preserved woolly dog pelt from "Mutton", collected in 1859. Mutton is the only known example of an Indigenous North American dog with dominant precolonial ancestry postdating the onset of settler colonialism. We identified candidate genetic variants potentially linked with their distinct woolly phenotype. We integrated these data with interviews from Coast Salish Elders, Knowledge Keepers, and weavers about shared traditional knowledge and memories surrounding woolly dogs, their importance within Coast Salish societies, and how colonial policies led directly to their disappearance.

Published
2023
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40. Katalysator

Author

Bach (Red), Lone-Pia, Edman, Victor, Bengtsdotter, Charlotta, Bergström, Anders, Johansson, Per- Anders, Svärdson Wächter, Ylva, Wenander, Vicki, Bach (Red), Lone-Pia, Edman, Victor, Bengtsdotter, Charlotta, Bergström, Anders, Johansson, Per- Anders, Svärdson Wächter, Ylva, and Wenander, Vicki

Abstract

Restaureringskonsten med sina långa tidsperspektiv är i sig hållbar, och den har betydande kunskap att tillföra dagens diskussion. Dess metoder stärker de kulturella och socialt engagerande processer som fler behöver vara delaktiga i för att gemensamt definiera vad som redan är – och som på sikt kommer att bli – vårt kulturarv. Arkitekturen berättar om förfluten tid, länkar ihop oss med tidigare generationer, skapar sammanhang och stabilitet. Den ger oss ramar för social interaktion, skapar tillhörighet till platser, samhörighet med andra människor och är identitetsskapande. I det perspektivet borde återbruk av byggnader och miljöer vara en självklar pusselbit i ett hållbart samhällsbyggande. Men fler behöver se det befintliga som resurser med hög potential, med målet att hitta lösningar för hur man på bästa sätt kan förändra och vidareutveckla utan att betydande värden går förlorade. Får behovet av omställning till ett mer hållbart samhällsbyggande konsekvenser för restaureringskonsten, eller kan dess metoder rent av vara en katalysator för att vidga och förändra vår syn på kunskapsfältet?

Published
2023

41. I städernas mitt : Restaurering i miljömedvetandets tid

Author

Bergström, Anders and Bergström, Anders

Abstract

Miljömedvetandets genombrott i Sverige brukar fixeras till slutet av 1960- och början av 1970-talet. Naturvårdsverket grundades exempelvis 1967, almstriden ägde rum 1971 och den internationella miljökonferensen i Stockholm gick av stapeln året därpå. Inom byggnadsvård och restaurering kom Byggnadsvårdsåret 1975 att spela en viktig roll – på initiativ av Europarådet – och konkreta resultat kunde skönjas under andra hälften av 1970-talet. En starkt bidragande orsak var den växande opinionen mot samtida stadsomvandlingar. Men såväl miljömedvetandet som intresset för städernas äldre bebyggelse hade i själva verket växt fram under en längre period, i växelspel med de accelererande tillväxtprocesserna. I synnerhet åren kring 1960 var betydelsefulla för den förändrade syn på stadsmiljö som efter hand etablerades, framförallt under inflytande av amerikanska skribenter. Förändringarna kan beskrivas som en gradvis förskjutning av intresset från enskilda monument till samlad bebyggelse, men också som en förskjutning mot synen på äldre bebyggelse som en materiell resurs snarare än ett kulturhistoriskt problem. Parallellt med det växande intresset för samlad bebyggelse pågick en omvärdering av hur enskilda monument skulle bevaras, där materiella egenskaper fick större betydelse på bekostnad av kulturhistoriska faktorer. I båda fallen fanns föregångare från det tidiga 1900-talet, med exempel som Arkitekturminnesföreningen och Gamla svenska städer, då en motsvarande process hade ägt rum och på samma sätt orsakats av omfattande samhällsförändringar. Ämnet är stort, och den följande undersökningen är därför begränsad i tid och rum Betoningen ligger på Stockholm med utblickar framförallt mot de mellansvenska städer som stod i fokus för samtida stadsomvandlingar. Avsikten är att studera hur kunskapen utvecklades och förmedlades genom sinsemellan olika aktörer, från det sena 1950-talets ifrågasättande av konsumtionssamhället, till det växande intresset för stadsmiljö och reformeringen, Part of book: ISBN 978-91-89490-11-6QC 20230629

Published
2023

42. Katalysator : Restaureringskonst 2022–2023

Author

Bengtsdotter, Charlotta, Bergström, Anders, Johansson, Per-Anders, Svärdson Wächter, Ylva, Wenander, Vicki, Bengtsdotter, Charlotta, Bergström, Anders, Johansson, Per-Anders, Svärdson Wächter, Ylva, and Wenander, Vicki

Abstract

Restaureringskonsten med sina långa tidsperspektiv är i sig hållbar, och den har betydande kunskap att tillföra dagens diskussion. Dess metoder stärker de kulturella och socialt engagerande processer som fler behöver vara delaktiga i för att gemensamt definiera vad som redan är – och som på sikt kommer att bli – vårt kulturarv. Arkitekturen berätar om förfluten tid, länkar ihop oss med tidigare generationer, skapar sammanhang och stabiblitet. Den ger oss ramar för social interaktion, skapar tillhörighet till platser, samhörighet med andra människor och är identitetsskapande. I det perspektivet borde återbruk av byggnader och miljöer vara en självklar pusselbit i ett hållbart samhällsbyggande. Men fler behöver se det befintliga som resurser med hög potential, med målet att hitta lösningar för hur man på bästa sätt kan förändra och vidareutveckla utan att betydande värden går förlorade. Får behovet av omställning till ett mer hållbart samhällsbyggande konsekvenser för restaureringskonsten, eller kan dess metoder rent av vara en katalysator för att vidga och förändra vår syn på kunskapsfältet?, QC 20231122

Published
2023

43. Katalysator : Staden, platsen, rummet, hantverket och framtiden

Author

Bengtsdotter, Charlotta, Bergström, Anders, Johansson, Per-Anders, Svärdson Wächter, Ylva, Wenander, Vicki, Bengtsdotter, Charlotta, Bergström, Anders, Johansson, Per-Anders, Svärdson Wächter, Ylva, and Wenander, Vicki

Abstract

QC 20230704

Published
2023

44. Ancient and recent origins of shared polymorphisms in yeast

Author

Tellini, Nicolò, primary, De Chiara, Matteo, additional, Mozzachiodi, Simone, additional, Tattini, Lorenzo, additional, Vischioni, Chiara, additional, Naumova, Elena, additional, Warringer, Jonas, additional, Bergström, Anders, additional, and Liti, Gianni, additional

Published
2023
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50. Critical Historiography

Author

Bergström, Anders and Bergström, Anders

Abstract

QC 20240815

Published
2022

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