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16 results on '"Benziane-Ouaritini, Nicolas"'

7. Prostatectomy Bed Image-guided Dose-escalated Salvage Radiotherapy (SPIDER): An International Multicenter Retrospective Study

Author

Benziane-Ouaritini, Nicolas, Zilli, Thomas, Giraud, Antoine, Ingrosso, Gianluca, Di Staso, Mario, Trippa, Fabio, Pommier, Pascal, Meyer, Emmanuel, Francolini, Giulio, Schick, Ulrike, Pasquier, David, Marc Cosset, Jean, Magne, Nicolas, Martin, Etienne, Gnep, Kémara, Renard-Penna, Raphaelle, Anger, Ewen, Achard, Vérane, Giraud, Nicolas, Aristei, Cynthia, Ferrari, Victoria, Pasquier, Corentin, Zaine, Hind, Osman, Osman, Detti, Beatrice, Perennec, Tanguy, Mihoci, Inga, Supiot, Stéphane, Latorzeff, Igor, and Sargos, Paul

Published
2023
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8. Highly hypofractionated schedules for localized prostate cancer: Recommendations of the GETUG radiation oncology group

Author

Lapierre, Ariane, Hennequin, Christophe, Beneux, Amandine, Belhomme, Sarah, Benziane Ouaritini, Nicolas, Biston, Marie-Claude, Crehange, Gilles, de Crevoisier, Renaud, Dumas, Jean-luc, Fawzi, Maher, Lisbona, Albert, Pasquier, David, Pelissier, Sandra, Graff-Cailleaud, Pierre, Pommier, Pascal, Sargos, Paul, Simon, Jean-Marc, Supiot, Stéphane, Tantot, Florence, and Chapet, Olivier

Published
2022
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10. Consolidative Radiotherapy for Metastatic Urothelial Bladder Cancer Patients with No Progression and with No More than Five Residual Metastatic Lesions Following First-Line Systemic Therapy: A Retrospective Analysis

Author

Aboudaram, Amélie, primary, Chaltiel, Léonor, additional, Pouessel, Damien, additional, Graff-Cailleaud, Pierre, additional, Benziane-Ouaritini, Nicolas, additional, Sargos, Paul, additional, Schick, Ulrike, additional, Créhange, Gilles, additional, Cohen-Jonathan Moyal, Elizabeth, additional, Chevreau, Christine, additional, and Khalifa, Jonathan, additional

Published
2023
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11. Salvage radiotherapy guided by functional imaging for macroscopic local recurrence following radical prostatectomy: A multicentric retrospective study.

Author

Benziane Ouaritini, Nicolas, primary, Zilli, Thomas, additional, Ingrosso, Gianluca, additional, Pasquier, David, additional, renard Penna, Raphaelle, additional, Ferrari, Victoria, additional, Achard, Verane, additional, Pasquier, Corentin, additional, Perennec, Tanguy, additional, Di Staso, Mario, additional, Mihoci, Inga, additional, Trippa, Fabio, additional, Francolini, Giulio, additional, Meyer, Emmanuel, additional, Schick, Ulrike, additional, Cosset, Jean Marc, additional, Martin, Etienne, additional, Supiot, Stephane, additional, Latorzeff, Igor, additional, and Sargos, Paul, additional

Published
2022
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12. Restaging of Patients with Persistently Elevated Prostate-specific Antigen After Radical Prostatectomy Using [68Ga]-PSMA-11 Positron Emission Tomography/Computed Tomography: Impact on Disease Management

Author

Gauthé, Mathieu, Sargos, Paul, Benziane Ouaritini, Nicolas, Barret, Eric, Beauval, Jean-Baptiste, Brureau, Laurent, Créhange, Gilles, Dariane, Charles, Fiard, Gaëlle, Fromont, Gaëlle, Mathieu, Romain, Renard-Penna, Raphaële, Roubaud, Guilhem, Ruffion, Alain, Rouprêt, Morgan, and Ploussard, Guillaume

Published
2022
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16. Post-Operative Radiotherapy in Prostate Cancer: Is It Time for a Belt and Braces Approach?

Author

Giraud N, Benziane-Ouaritini N, Schick U, Beauval JB, Chaddad A, Niazi T, Faye MD, Supiot S, Sargos P, and Latorzeff I

Abstract

Approximately 30% of patients treated with radical prostatectomy (RP) for prostate cancers experience biochemical recurrence (BCR). Post-operative radiation therapy (RT) can be either offered immediately after the surgery in case of aggressive pathological features or proposed early if BCR occurs. Until recently, little data were available regarding the optimal RT timing, protocol, volumes to treat, and the benefit of adding androgen deprivation therapies to post-operative RT. In this review, we aim to pragmatically discuss current literature data on these points. Early salvage RT appears to be the optimal post-operative approach, improving oncological outcomes especially with low prostate-specific antigen (PSA) levels, as well as sparing several unnecessary adjuvant treatments. The standard RT dose is still 64-66 Gy to the prostate bed in conventional fractionation, but hypofractionation protocols are emerging pending on late toxicity data. Several scientific societies have published contouring atlases, even though they are heterogeneous and deserve future consensus. During salvage RT, the inclusion of pelvic lymph nodes is also controversial, but preliminary data show a possible benefit for PSA > 0.34 ng/ml at the cost of increased hematological side effects. Concomitant ADT and its duration are also discussed, possibly advantageous (at least in terms of metastasis-free survival) for PSA rates over 0.6 ng/ml, taking into account life expectancy and cardiovascular comorbidities. Intensified regimens, for instance, with new-generation hormone therapies, could further improve outcomes in carefully selected patients. Finally, recent advances in molecular imaging, as well as upcoming breakthroughs in genomics and artificial intelligence tools, could soon reshuffle the cards of the current therapeutic strategy., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Giraud, Benziane-Ouaritini, Schick, Beauval, Chaddad, Niazi, Faye, Supiot, Sargos and Latorzeff.)

Published
2021
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