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26 results on '"Bendtsen, Mette Dahl"'

1. Treatment strategies, outcomes and prognostic factors in 291 patients with secondary CNS involvement by diffuse large B-cell lymphoma

Author

El-Galaly, Tarec Christoffer, Cheah, Chan Yoon, Bendtsen, Mette Dahl, Nowakowski, Grzegorz S., Kansara, Roopesh, Savage, Kerry J., Connors, Joseph M., Sehn, Laurie H., Goldschmidt, Neta, Shaulov, Adir, Farooq, Umar, Link, Brian K., Ferreri, Andrés J.M., Calimeri, Teresa, Cecchetti, Caterina, Dann, Eldad J., Thompson, Carrie A., Inbar, Tsofia, Maurer, Matthew J., Gade, Inger Lise, Juul, Maja Bech, Hansen, Jakob W., Holmberg, Staffan, Larsen, Thomas S., Cordua, Sabrina, Mikhaeel, N. George, Hutchings, Martin, Seymour, John F., Clausen, Michael Roost, Smith, Daniel, Opat, Stephen, Gilbertson, Michael, Thanarajasingam, Gita, and Villa, Diego

Published
2018
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11. Trends in diagnostic patterns and mortality in emergency ambulance service patients in 2007−2014: a population-based cohort study from the North Denmark Region

Author

Christensen, Erika Frischknecht, primary, Bendtsen, Mette Dahl, additional, Larsen, Thomas Mulvad, additional, Jensen, Flemming Bøgh, additional, Lindskou, Tim Alex, additional, Holdgaard, Hans Ole, additional, Hansen, Poul Anders, additional, Johnsen, Søren Paaske, additional, and Christiansen, Christian Fynbo, additional

Published
2017
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12. Anthropometrics and prognosis in diffuse large B-cell lymphoma:a multicentre study of 653 patients

Author

Bendtsen, Mette Dahl, Munksgaard, Peter Svenssen, Severinsen, Marianne Tang, Bekric, Eric, Brieghel, Christian, Nielsen, Kristina Buchardi, Brown, Peter de Nully, Dybkær, Karen, Johnsen, Hans Erik, Bøgsted, Martin, El-Galaly, Tarec Christoffer, Bendtsen, Mette Dahl, Munksgaard, Peter Svenssen, Severinsen, Marianne Tang, Bekric, Eric, Brieghel, Christian, Nielsen, Kristina Buchardi, Brown, Peter de Nully, Dybkær, Karen, Johnsen, Hans Erik, Bøgsted, Martin, and El-Galaly, Tarec Christoffer

Abstract

Objective: The impact of body mass index (BMI) and body surface area (BSA) on survival in diffuse large B-cell lymphoma (DLBCL) is controversial. Recent studies show superior outcomes for overweight and obese patients. Patients and methods: A total of 653 R-CHOP(-like)-treated DLBCL patients were included in this retrospective cohort study. Patients, baseline clinicopathologic characteristics and treatment information were retrieved from the Danish Lymphoma Registry. Anthropometric measures were obtained from chemotherapy prescription charts. Results: Underweight (BMI <18.5 kg/m2) was associated with significantly worse progression-free survival (PFS) for male patients only in sex-stratified analyses (HR 3.92, 95% CI: 1.57–9.75, P = 0.003, for males; HR 1.65, 95% CI: 0.90–3.02, P = 0.107, for females). In multivariate analyses, underweight was associated with worse PFS for both sexes (HR 5.34, 95% CI: 2.07–13.79, P = 0.001, for males; HR 2.14, 95% CI: 1.12–4.08, P = 0.021, for females). Similar results were obtained in analyses of overall survival. In crude analyses, BSA <1.8 m2 was associated with worse PFS for men and women (HR 1.65, 95% CI: 1.03–2.65, P = 0.039, for men; HR 1.62, 95% CI: 1.03–2.56, P = 0.037, for women). In multivariate analyses, however, these associations diminished. Conclusions: Our study demonstrates that underweight DLBCL patients have worse outcomes following R-CHOP as compared to normal as well as overweight patients.

Published
2017

14. Anthropometrics and prognosis in diffuse large B-cell lymphoma: a multicentre study of 653 patients

Author

Bendtsen, Mette Dahl, primary, Munksgaard, Peter Svenssen, additional, Severinsen, Marianne Tang, additional, Bekric, Eric, additional, Brieghel, Christian, additional, Nielsen, Kristina Buchardi, additional, Brown, Peter de Nully, additional, Dybkaer, Karen, additional, Johnsen, Hans Erik, additional, Bøgsted, Martin, additional, and El-Galaly, Tarec Christoffer, additional

Published
2017
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17. An International Collaborative Study of Outcome and Prognostic Factors in Patients with Secondary CNS Involvement By Diffuse Large B-Cell Lymphoma

Author

El-Galaly, Tarec Christoffer, primary, Cheah, Chan Yoon, additional, Bendtsen, Mette Dahl, additional, Thanarasjasingam, Gita, additional, Kansara, Roopesh, additional, Savage, Kerry J, additional, Connors, Joseph M., additional, Goldschmidt, Neta, additional, Shaulov, Adir, additional, Farooq, Umar, additional, Sehn, Laurie H, additional, Dann, Eldad J, additional, Thompson, Carrie A, additional, Inbar, Tsofia, additional, Link, Brian K, additional, Maurer, Matthew J, additional, Gade, Inger Lise, additional, Juul, Maja Bech, additional, Hansen, Jakob W, additional, Holmberg, Staffan, additional, Larsen, Thomas S, additional, Opat, Stephen, additional, Mikhaeel, N George, additional, Seymour, John F, additional, Clausen, Michael Roost, additional, Smith, Daniel, additional, Gilbertson, Michael, additional, Nowakowski, Grzegorz S, additional, Cordua, Sabrina, additional, Hutchings, Martin, additional, and Villa, Diego, additional

Published
2016
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22. Inherited Inflammatory Response Genes Are Associated with B-Cell Non-Hodgkin’s Lymphoma Risk and Survival

Author

Nielsen, Kaspar René, primary, Steffensen, Rudi, additional, Bendtsen, Mette Dahl, additional, Rodrigo-Domingo, Maria, additional, Baech, John, additional, Haunstrup, Thure Mors, additional, Bergkvist, Kim Steve, additional, Schmitz, Alexander, additional, Boedker, Julie Stoeveve, additional, Johansen, Preben, additional, Dybkaeær, Karen, additional, Boeøgsted, Martin, additional, and Johnsen, Hans Erik, additional

Published
2015
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25. Gender-Based Differences in Efficacy of Immuno-Chemotherapy for Diffuse Large B-Cell Lymphoma Revisited: A Danish Population-Based Study

Author

Bendtsen, Mette Dahl, Jakobsen, Lasse Hjort, Jørgensen, Judit Mészáros, Johnsen, Hans Erik, Josefsson, Pär Lars, Poulsen, Christian Bjørn, Starklint, Jørn, Stein, Gabriela Felicia, Pedersen, Per Trøllund, Christensen, Jacob Haaber, Bøgsted, Martin, Brown, Peter de Nully, and El-Galaly, Tarec Christoffer

Published
2017
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26. Trends in diagnostic patterns and mortality in emergency ambulance service patients in 2007-2014: a population-based cohort study from the North Denmark Region.

Author

Christensen EF, Bendtsen MD, Larsen TM, Jensen FB, Lindskou TA, Holdgaard HO, Hansen PA, Johnsen SP, and Christiansen CF

Subjects
Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Child, Child, Preschool, Cohort Studies, Denmark epidemiology, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Prevalence, Registries, Regression Analysis, Sex Distribution, Time Factors, Young Adult, Ambulances, Comorbidity trends, Emergency Medical Services statistics & numerical data, Hospital Mortality trends
Abstract

Objective: Demand for ambulances is growing. Nevertheless, knowledge is limited regarding diagnoses and outcomes in patients receiving emergency ambulances. This study aims to examine time trends in diagnoses and mortality among patients transported with emergency ambulance to hospital., Design: Population-based cohort study with linkage of Danish national registries., Setting: The North Denmark Region in 2007-2014., Participants: Cohort of 148 757 patients transported to hospital by ambulance after calling emergency services., Main Outcome Measures: The number of emergency ambulance service patients, distribution of their age, sex, hospital diagnoses, comorbidity, and 1-day and 30-day mortality were assessed by calendar year. Poisson regression with robust variance estimation was used to estimate both age-and sex-adjusted relative risk of death and prevalence ratios for Charlson Comorbidity Index (CCI) to allow comparison by year, with 2007 as reference year., Results: The annual number of emergency ambulance service patients increased from 24.3 in 2007 to 40.2 in 2014 per 1000 inhabitants. The proportions of women increased from 43.1% to 46.4% and of patients aged 60+ years from 39.9% to 48.6%, respectively. The proportion of injuries gradually declined, non-specific diagnoses increased, especially the last year. Proportion of patients with high comorbidity (CCI≥3) increased from 6.4% in 2007 to 9.4% in 2014, corresponding to an age- and sex-adjusted prevalence ratio of 1.27 (95% CI 1.16 to 1.39). The 1-day and 30 day mortality decreased from 2.40% to 1.21% and from 5.01% to 4.36%, respectively, from 2007 to 2014, corresponding to age-adjusted and sex-adjusted relative risk of 0.43 (95% CI 0.37 to 0.50) and 0.72 (95% CI 0.66 to 0.79), respectively., Conclusion: During the 8-year period, the incidence of emergency ambulance service patients, the proportion of women, elderly, and non-specific diagnoses increased. The level of comorbidity increased substantially, whereas the 1-day and 30-day mortality decreased., Competing Interests: Competing interests: None declared., (© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)

Published
2017
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