181 results on '"Bendlová B"'
Search Results
2. Associations of polymorphisms in the candidate genes for Alzheimer’s disease BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance
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Vacínová, Gabriela, Vejražková, D., Lukášová, P., Lischková, O., Dvořáková, K., Rusina, R., Holmerová, I., Vaňková, H., Včelák, J., Bendlová, B., and Vaňková, M.
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- 2017
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3. The differences between aromatizable and non-aromatizable androgens in relation to body composition and metabolic syndrome risk factors in men
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Pospíšilová, H., Vaňková, M., Hill, M., Meloun, M., Bendlová, B., Dušková, M., and Stárka, L.
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- 2012
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4. Somatic mutations in the RET proto-oncogene in sporadic medullary thyroid carcinomas
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Dvorakova, S., Vaclavikova, E., Sykorova, V., Vcelak, J., Novak, Z., Duskova, J., Ryska, A., Laco, J., Cap, J., Kodetova, D., Kodet, R., Krskova, L., Vlcek, P., Astl, J., Vesely, D., and Bendlova, B.
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- 2008
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5. Circulating β2 Microglobulin in Relation to Bone Metabolism: Implications for Bone Loss with Aging
- Author
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Zofková, I., Bahbouh, R., Bendlová, B., and Kancheva, R. L.
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- 1999
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6. Melanocortin Pathways: Suppressed and Stimulated Melanocortin-4 Receptor (MC4R)
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HAINER, V., primary, ALDHOON HAINEROVÁ, I., additional, KUNEŠOVÁ, M., additional, TAXOVÁ BRAUNEROVÁ, R., additional, ZAMRAZILOVÁ, H., additional, and BENDLOVÁ, B., additional
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- 2020
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7. Plasma Levels of Adipokines in Patients With Alzheimer’s Disease – Where Is the “Breaking Point” in Alzheimer’s Disease Pathogenesis?
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VAŇKOVÁ, M., primary, VACÍNOVÁ, G., additional, VČELÁK, J., additional, VEJRAŽKOVÁ, D., additional, LUKÁŠOVÁ, P., additional, RUSINA, R., additional, HOLMEROVÁ, I., additional, JAROLÍMOVÁ, E., additional, VAŇKOVÁ, H., additional, and BENDLOVÁ, B., additional
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- 2020
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8. Metabolic syndrome in young Czech women with polycystic ovary syndrome
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Vrbíková, J., Vondra, K., Cibula, D., Dvořáková, K., Stanická, S., Šrámková, D., Šindelka, G., Hill, M., Bendlová, B., and Škrha, J.
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- 2005
9. The CTLA4 +49 A/G dimorphism is not associated with type 1 diabetes in Czech children
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Cinek, O, Dřevínek, P, Šumník, Z, Bendlová, B, Koloušková, S, Šnajderová, M, and Vavřinec, J
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- 2002
10. Co má vědět chirurg o genetice karcinomů štítné žlázy.
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Bavor, P., Peková, B., Sýkorová, V., Bendlová, B., and Hoch, J.
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- 2020
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11. Expression Profiling of Nme7 Interactome in Experimental Models of Metabolic Syndrome
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ŠEDOVÁ, L., primary, ŠKOLNÍKOVÁ, E., additional, HODÚLOVÁ, M., additional, VČELÁK, J., additional, ŠEDA, O., additional, and BENDLOVÁ, B., additional
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- 2018
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12. ZBTB16 and Metabolic Syndrome: a Network Perspective
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ŠEDA, O., primary, ŠEDOVÁ, L., additional, VČELÁK, J., additional, VAŇKOVÁ, M., additional, LIŠKA, F., additional, and BENDLOVÁ, B., additional
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- 2017
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13. ZBTB16 Gene Variability Influences Obesity-Related Parameters and Serum Lipid Levels in Czech Adults
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BENDLOVÁ, B., primary, VAŇKOVÁ, M., additional, HILL, M., additional, VACÍNOVÁ, G., additional, LUKÁŠOVÁ, P., additional, VEJRAŽKOVÁ, D., additional, ŠEDOVÁ, L., additional, ŠEDA, O., additional, and VČELÁK, J., additional
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- 2017
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14. Association of obesity susceptibility gene variants with metabolic syndrome and related traits in 1,443 Czech adolescents
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Dušátková L, Zamrazilová H, Sedláčková B, Včelák J, Hlavatý P, Aldhoon Hainerová I, Vlasta Korenkova, Bradnová O, Bendlová B, Kunešová M, and Hainer V
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Blood Glucose ,Male ,Metabolic Syndrome ,Adolescent ,Anthropometry ,C-Peptide ,Genotype ,Overweight ,Lipids ,Cohort Studies ,Gene Frequency ,Thinness ,Humans ,Insulin ,Female ,Genetic Predisposition to Disease ,Obesity ,Adiposity ,Czech Republic ,Genome-Wide Association Study - Abstract
Genome-wide association studies have revealed several gene variants associated with obesity; however, only a few studies have further investigated their association with metabolic syndrome. We performed a study of eleven variants in/near genes TMEM18, SH2B1, KCTD15, PCSK1, BDNF, SEC16B, MC4R, and FTO in Czech adolescents and analysed their association with obesity, metabolic syndrome and related traits. Genotyping was performed in 1,443 adolescents aged 13.0-17.9 years. Anthropometric parameters, biochemical parameters and blood pressure were assessed. Metabolic syndrome was defined according to the International Diabetes Federation. The FTO rs9939609 variant was associated with overweight/obesity (OR 1.40, 95% CI 1.21-1.63, P0.001). The minor allele of TMEM18 rs7561317 was related to underweight (OR 1.78, 95% CI 1.14-2.79, P = 0.015). BDNF rs925946 and MC4R rs17782313 were associated with metabolic syndrome (OR 1.53, 95% CI 1.14-2.04, P = 0.005; 1.51, 95% CI 1.12-2.04, P = 0.009). The PCSK1 rs6235 variant was negatively related to increased blood glucose (OR 0.69, 95% CI 0.49-0.97, P = 0.040). In conclusion, the FTO variant was associated with overweight/obesity in Czech adolescents. Moreover, MC4R and BDNF variants increased the risk of metabolic syndrome, probably through their effect on abdominal obesity. The PCSK1 variant may have a protective role in the development of type 2 diabetes.
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- 2013
15. Association of Adenovirus 36 Infection With Obesity-Related Gene Variants in Adolescents
- Author
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DUŠÁTKOVÁ, L., primary, ZAMRAZILOVÁ, H., additional, ALDHOON HAINEROVÁ, I., additional, ATKINSON, R. L., additional, SEDLÁČKOVÁ, B., additional, LEE, Z. P., additional, VČELÁK, J., additional, BENDLOVÁ, B., additional, KUNEŠOVÁ, M., additional, and HAINER, V., additional
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- 2015
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16. Obesity and Infection: Reciprocal Causality
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HAINER, V., primary, ZAMRAZILOVÁ, H., additional, KUNEŠOVÁ, M., additional, BENDLOVÁ, B., additional, and ALDHOON-HAINEROVÁ, I., additional
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- 2015
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17. Fatty Acid Composition of Adipose Tissue Triglycerides in Obese Diabetic Women After Bariatric Surgery: a 2-Year Follow up
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KUNEŠOVÁ, M., primary, SEDLÁČKOVÁ, B., additional, BRADNOVÁ, O., additional, TVRZICKÁ, E., additional, STAŇKOVÁ, B., additional, ŠRÁMKOVÁ, P., additional, DOLEŽALOVÁ, K., additional, KALOUSKOVÁ, P., additional, HLAVATÝ, P., additional, HILL, M., additional, BENDLOVÁ, B., additional, FRIED, M., additional, HAINER, V., additional, and VRBÍKOVÁ, J., additional
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- 2015
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18. Metabolic and Hormonal Consequencies of the „Obesity Risk“ MC4R Variant (rs12970134) in Czech Women
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BRADNOVÁ, O., primary, VEJRAŽKOVÁ, D., additional, VAŇKOVÁ, M., additional, LUKÁŠOVÁ, P., additional, VČELÁK, J., additional, STANICKÁ, S., additional, DVOŘÁKOVÁ, K., additional, and BENDLOVÁ, B., additional
- Published
- 2015
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19. Fat Mass and Obesity Associated Gene Variants Are Associated With Increased Growth Hormone Levels and Affect Glucose and Lipid Metabolism in Lean Women
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LUKÁŠOVÁ, P., primary, VAŇKOVÁ, M., additional, VČELÁK, J., additional, VEJRAŽKOVÁ, D., additional, BRADNOVÁ, O., additional, STANICKÁ, S., additional, HAINER, V., additional, and BENDLOVÁ, B., additional
- Published
- 2015
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20. Reduced Sulfotransferase SULT2A1 Activity in Patients With Alzheimer´s Disease
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VAŇKOVÁ, M., primary, HILL, M., additional, VELÍKOVÁ, M., additional, VČELÁK, J., additional, VACÍNOVÁ, G., additional, LUKÁŠOVÁ, P., additional, VEJRAŽKOVÁ, D., additional, DVOŘÁKOVÁ, K., additional, RUSINA, R., additional, HOLMEROVÁ, I., additional, JAROLÍMOVÁ, E., additional, VAŇKOVÁ, H., additional, and BENDLOVÁ, B., additional
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- 2015
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21. [Association of insulin gene variants with type 1 diabetes mellitus in Czech population]
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Ondrej Cinek, Drevínek P, Sumník Z, Bendlová B, and Vavrinec J
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Male ,Diabetes Mellitus, Type 1 ,Phenotype ,Gene Frequency ,Genotype ,HLA-DQ Antigens ,Humans ,Insulin ,Female ,Minisatellite Repeats ,Child ,Polymorphism, Single Nucleotide ,Czech Republic - Abstract
The objective of the study was to quantify the association of insulin gene variants with type 1 diabetes mellitus (TIDM) in the Czech population.In an association study, we compared genotypes of 332 T1DM patients (age at T1DM onset was 8.1 +/- 4.4 yrs) with 292 healthy nondiabetic controls of similar age. All subjects were previously genotyped for HLA-DQB1, -DQA1 polymorphisms and DRB1*04 subtypes. The insulin gene was typed using the -23 HphI single nucleotide polymorphism after we had demonstrated a nearly complete linkage disequilibrium between this polymorphism, and the etiological VNTR in the Czech population. The protective variant of the insulin gene was present in 24% T1DM patients, and in 48% controls (OR=0.34, CI 95% 0.24-0.48), a risk comparable to weaker-associated HLA-DQ alleles. The association was independent of the HLA-conferred T1DM risk. The insulin gene polymorphism had no influence on the age at T1DM onset.We conclude that the insulin gene genotyping confers important information on T1DM risk in our population, and should be used in determining the disease risk along with the HLA-DQ typing.
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- 2004
22. T2D Risk Haplotypes of the TCF7L2 Gene in the Czech Population Sample: the Association With Free Fatty Acids Composition
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VČELÁK, J., primary, VEJRAŽKOVÁ, D., additional, VAŇKOVÁ, M., additional, LUKÁŠOVÁ, P., additional, BRADNOVÁ, O., additional, HÁLKOVÁ, T., additional, BEŠŤÁK, J., additional, ANDĚLOVÁ, K., additional, KVASNIČKOVÁ, H., additional, HOSKOVCOVÁ, P., additional, VONDRA, K., additional, VRBÍKOVÁ, J., additional, and BENDLOVÁ, B., additional
- Published
- 2012
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23. Neuromedin Beta: P73t Polymorphism in Overweight and Obese Subjects
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Spálová, J, primary, Zamrazilová, H, additional, Včelák, J, additional, Vaňková, M, additional, Lukášová, P, additional, Hill, M, additional, Hlavatá, K, additional, Šrámková, P, additional, Fried, M, additional, Aldhoon, B, additional, Kunešová, M, additional, Bendlová, B, additional, and Hainer, V, additional
- Published
- 2008
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24. Dehydroepiandrosterone in Relation to Adiposity, Glucose Tolerance and Lipid Spectra in Czech Non-Diabetic Population
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Bendlová, B, primary, Vrbíková, J, additional, Hill, M, additional, Vaňková, M, additional, Lukášová, P, additional, Včelák, J, additional, Vejražková, D, additional, Dvořáková, K, additional, Hampl, R, additional, Vondra, K, additional, and Stárka, L, additional
- Published
- 2008
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25. Screening of Mutations and Polymorphisms in the Glucokinase Gene in Czech Diabetic and Healthy Control Populations
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Lukášová, P, primary, Včelák, J, additional, Vaňková, M, additional, Vejražková, D, additional, Andělová, K, additional, and Bendlová, B, additional
- Published
- 2008
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26. PPAR γ2 Pro12Ala Polymorphism in Relation to Free Fatty Acids Concentration and Composition in Lean Healthy Czech Individuals with and without Family History of Diabetes Type 2
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Bendlová, B, primary, Vejražková, D, additional, Včelák, J, additional, Lukášová, P, additional, Burkoňová, D, additional, Kunešová, M, additional, Vrbíková, J, additional, Dvořáková, K, additional, Vondra, K, additional, and Vaňková, M, additional
- Published
- 2008
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27. Role of Hereditary Factors in Weight Loss and Its Maintenance
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Hainer, V, primary, Zamrazilová, H, additional, Spálová, J, additional, Hainerová, I, additional, Kunešová, M, additional, Aldhoon, B, additional, and Bendlová, B, additional
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- 2008
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28. Metabolic and Hormonal Consequencies of the Obesity Risk" MC4R Variant (rs12970134) in Czech Women.
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BRADNOVÁ, O., VEJRAŽKOVÁ, D., VAŇKOVÁ, M., LUKÁŠOVÁ, P., VČELÁK, J., STANICKÁ, S., DVOŘÁKOVÁ, K., and BENDLOVÁ, B.
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METABOLIC disorders ,OBESITY in women ,CZECHS ,GENETIC mutation ,POLYCYSTIC ovary syndrome ,DISEASES ,OBESITY risk factors - Abstract
Although the mutations in MC4R gene became known as the most common genetic cause of human obesity, the effect of rs12970134 A/G near MC4R gene on insulin resistance has been described. The aim of this study was to determine the effect of rs12970134 on obesity, hormone levels, and glucose metabolism in a cohort of women varying in glucose tolerance: 850 normoglycemic women, 423 diagnosed with polycystic ovary syndrome (PCOS), 402 gestational diabetics (GDM), and 250 type 2 diabetic (T2D) women. We did not confirm the explicit effect of rs12970134 on obesity. However, the influence of the A-allele on body adiposity index was observed in a cohort of women diagnosed with PCOS. In normoglycemic women, the A-allele carriership was associated with lower fasting levels of glucose, insulin, C-peptide, and index of insulin resistance. Furthermore, higher levels of growth hormone, leptin and SHBG, and lower levels of fT3, testosterone, and androstenedione were recorded in normoglycemic A-allele carriers. In conclusion, the study presents the evidence of the impact of rs12970134 on complex hypothalamic regulations. [ABSTRACT FROM AUTHOR]
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- 2015
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29. New Multiple Somatic Mutations in the RET Proto-oncogene Associated with a Sporadic Medullary Thyroid Carcinoma
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Dvořáková, Š., primary, Václavíková, E., additional, Sýkorová, V., additional, Dušková, J., additional, Vlček, P., additional, Ryška, A., additional, Novák, Z., additional, and Bendlová, B., additional
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- 2006
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30. Differences in Type I Diabetes Mellitus of Young Adults with and without Thyroid Autoimmunity
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Vondra, K., primary, Vrbíková, J., additional, Bendlová, B., additional, Dvorakova, K., additional, Sterzl, I., additional, and Vondrova, M., additional
- Published
- 2005
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31. Screening of six risk exons of the RET proto-oncogene in families with medullary thyroid carcinoma in the Czech Republic
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Jindřichová, Š, primary, Včelák, J, additional, Vlček, P, additional, Neradilová, M, additional, Němec, J, additional, and Bendlová, B, additional
- Published
- 2004
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32. Mutations and intronic variants in the HNF-1beta gene in a group of German and Czech Caucasians with type 2 diabetes mellitus and progressive diabetic nephropathy
- Author
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Selisko, T., primary, Včelák, J., additional, Bendlová, B., additional, Graessler, J., additional, Schwarz, P., additional, and Schulze, J., additional
- Published
- 2002
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33. Systemic insulin-like growth factor-I, insulin and vitamin D status in relation to age-associated bone loss in women
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žofková, I., primary, Bahbouh, R., additional, and Bendlová, B., additional
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- 2001
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34. Genetic Variation at the Apo B 3’VNTR in Czech General Population and in Czech Diabetes Mellitus Type II Patient Group
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Mazura, I., primary, Bendlová, B., additional, Vannková, M., additional, Vcelák, J., additional, Perušicová, J., additional, Svatoš, J., additional, Štefek, M., additional, and Zvárová, J., additional
- Published
- 2001
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35. An analysis of the relationship between insulin resistance and the activity of steroid C17,20-lyase and 3β-hydroxysteroid dehydrogenase in ovaries and adrenals in women with polycystic ovary syndrome
- Author
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Vrbíková, J., primary, Hill, M., additional, Stárka, L., additional, Vondra, K., additional, Sulcová, J., additional, Snajderová, M., additional, Cibula, D., additional, Pobisová, Z., additional, and Bendlová, B., additional
- Published
- 2000
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36. Is a Mutation of the ?3-Adrenergic Receptor Gene Related to Non-Insulin-dependent Diabetes Mellitus and Juvenile Hypertension in the Czech Population?
- Author
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BENDLOVÁ, B., primary, MAZURA, I., additional, VČELÁK, J., additional, PERUŠIČOVÁ, J., additional, PALYZOVÁ, D., additional, KLIMEŠ, I., additional, and ŠEBÖKOVÁ, E., additional
- Published
- 1997
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37. Hirschsprungova choroba a její genetické příčiny.
- Author
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Dvořáková, Š., Václavíková, E., Škába, R., Kavalcová, L., and Bendlová, B.
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HIRSCHSPRUNG'S disease ,TRANSCRIPTION factors ,PEDIATRIC gastroenterology ,CANCER patients ,COLON diseases - Abstract
Copyright of Czecho-Slovak Pediatrics / Česko-Slovenská Pediatrie is the property of Czech Medical Association of JE Purkyne and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2013
38. A Monoclonal Antibody Applicable for Determination of C-Peptide of Human Proinsulin by RIA
- Author
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HILGERT, I., primary, ŠTOLBA, P., additional, KRIŠTOFOVÁ, H., additional, ŠTEFANOV, I., additional, BENDLOVÁ, B., additional, LEBL, M., additional, and HOŘEJŠÍ, V., additional
- Published
- 1991
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39. PPARγ2 Pro12Ala Polymorphism in Relation to Free Fatty Acids Concentration and Composition in Lean Healthy Czech Individuals with and without Family History of Diabetes Type 2.
- Author
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Bendlová, B., Vejražková, D., Vcelák, J., Lukášová, P., Burkonová, D., Kunešová, M., Vrbíková, J., Dvoráková, K., Vondra, K., and Vanková, M.
- Subjects
FATTY acids ,HUMAN body composition ,UNSATURATED fatty acids ,INSULIN resistance ,DIABETES ,GENETIC polymorphisms ,HETEROGENEITY - Abstract
Free fatty acids (FFAs) are natural ligands of the PPAR?2 receptor. FFA plasma concentration and composition may represent one of the factors accounting for high heterogeneity of conclusions concerning the effect of the Pro12Ala on BMI, insulin sensitivity or diabetes type 2 (DM2) susceptibility. Our objective was to investigate the relation and possible interactions between the Pro12Ala polymorphism and FFA status, metabolic markers, and body composition in 324 lean nondiabetic subjects (M/F: 99/225; age 32±11 years; BMI 23.9±4.0 kg/m²) with and without family history of DM2. Family history of DM2 was associated with lower % PUFA and slightly higher % MUFA. The presence of Pro12Ala polymorphism was not associated with fasting plasma FFA concentration or composition, anthropometric or metabolic markers of glucose and lipid metabolism in tested population. However, the interaction of carriership status with FFA levels influenced the basal glucose levels, insulin sensitivity and disposition indices, triglycerides, HDL-cholesterol and leptin levels, especially in women. The metabolic effects of 12Ala carriership were influenced by FFA levels - the beneficial role of 12Ala was seen only in the presence of low concentration of plasma FFA. Surprisingly, a high PUFA/SFA ratio was associated with lower insulin sensitivity, the protective effect of 12Ala allele was apparent in subjects with family history of DM2. On the basis of our findings and published data we recommend the genotyping of diabetic patients for Pro12Ala polymorphism of the PPAR㬲 gene before treatment with thiazolidinediones and education of subjects regarding diet and physical activity, which modulate metabolic outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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40. The effects of long-term metformin treatment on adrenal and ovarian steroidogenesis in women with polycystic ovary syndrome.
- Author
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Vrbíková, J., Hill, M., Stárka, L., Cibula, D., Bendlová, B., Vondra, K., Šulcová, J., and Šnajderová, M.
- Published
- 2001
- Full Text
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41. Circulating beta(2) microglobulin in relation to bone metabolism: implications for bone loss with aging.
- Author
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Zofková, I, Bahbouh, R, Bendlová, B, and Kancheva, R L
- Abstract
The aim of this cross-sectional study was to evaluate the relationships between circulating beta(2) microglobulin (beta(2) m) and bone mineral density (BMD), parameters of bone remodeling, vitamin D metabolites, parathyroid hormone (PTH), estradiol levels, and age in a group of 165 clinically healthy or osteoporotic, but otherwise normal untreated women. In this group of women, systemic beta(2) m correlated with BMD (g/cm(2)) levels for total hip and Ward's triangle (r = -0.298, P < 0.0001; and r = -0.299, P < 0.0001, respectively), but only at the borderline level with BMD at the spine (r = -0.145, P = 0.0604). Serum beta(2) microglobulin markedly correlated with age (r = 0.512, P = 0.0001). beta(2) m levels correlated with indices of bone remodeling, as well as with serum creatinine and estradiol levels. However, after stratification of all analyses by age, body mass index, and serum 25OHD(3), 1, 25(OH)(2)D(3), PTH, or estradiol levels (using standard multiple regression and stepwise forward regression models), only 25OHD(3) was found to be an independent predictor of BMD at the hip, including Ward's triangle, as estradiol of BMD at the spine. On the other hand, beta(2) m was not associated with BMD at any of the measured regions. Also, no association was found between serum PTH and BMD values. Therefore, systemic beta(2) m seems to be an indicator of bone remodeling in the course of natural skeletal aging rather than a variable independently predicting bone loss. [ABSTRACT FROM AUTHOR]
- Published
- 1999
42. Circulating β2 Microglobulin in Relation to Bone Metabolism: Implications for Bone Loss with Aging.
- Author
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Zofková, I., Bahbouh, R., Bendlová, B., and Kancheva, R. L.
- Abstract
The aim of this cross-sectional study was to evaluate the relationships between circulating β
2 microglobulin (β2 m) and bone mineral density (BMD), parameters of bone remodeling, vitamin D metabolites, parathyroid hormone (PTH), estradiol levels, and age in a group of 165 clinically healthy or osteoporotic, but otherwise normal untreated women. In this group of women, systemic β2 m correlated with BMD (g/cm2 ) levels for total hip and Ward's triangle (r =−0.298, P < 0.0001; and r =−0.299, P < 0.0001, respectively), but only at the borderline level with BMD at the spine (r =−0.145, P= 0.0604). Serum β2 microglobulin markedly correlated with age (r = 0.512, P= 0.0001). β2 m levels correlated with indices of bone remodeling, as well as with serum creatinine and estradiol levels. However, after stratification of all analyses by age, body mass index, and serum 25OHD3 , 1,25(OH)2 D3 , PTH, or estradiol levels (using standard multiple regression and stepwise forward regression models), only 25OHD3 was found to be an independent predictor of BMD at the hip, including Ward's triangle, as estradiol of BMD at the spine. On the other hand, β2 m was not associated with BMD at any of the measured regions. Also, no association was found between serum PTH and BMD values. Therefore, systemic β2 m seems to be an indicator of bone remodeling in the course of natural skeletal aging rather than a variable independently predicting bone loss. [ABSTRACT FROM AUTHOR]- Published
- 1999
- Full Text
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43. Effect of 1,25(OH)2 vitamin D3 on circulating insulin-like growth factor-I and beta 2 microglobulin in patients with osteoporosis.
- Author
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Zofková, I, Kancheva, R L, and Bendlová, B
- Abstract
To test the hypothesis that growth factors mediate the stimulatory effect of 1,25(OH)2 vitamin D3 [1,25(OH)2D3] on bone remodeling in osteoporosis, the authors studied the effect of the secosteroid administration in two doses (1 microgram/day and 2 micrograms/day) for 14 days on circulating insulin-like growth factor-I (IGF-I), beta 2 microglobulin, and osteocalcin in 18 osteoporotic women. The biological effectiveness of the treatment was controlled by a decline of serum intact parathyroid hormone. Compared with the values before treatment, 1,25(OH)2D3 increased means of plasma IGF-I, beta 2 microglobulin, and serum osteocalcin significantly; however, the effects were only apparent after the higher dose of the drug (169 +/- 26 versus 134 +/- 28 ng/ml, P < 0.01; 2.08 +/- 0.1 versus 1.92 +/- 0.1 micrograms/ml, P < 0.05; and 8.5 +/- 1.3 versus 5.4 +/- 1.1 ng/ml, P < 0.01, respectively). The authors conclude that exogenous 1,25(OH)2D3 promotes the production of IGF-I and beta 2 microglobulin in osteoporotic patients in parallel to the marker of osteoblastic function, osteocalcin, which supports the tested hypothesis. [ABSTRACT FROM AUTHOR]
- Published
- 1997
44. Is a Mutation of the β3-Adrenergic Receptor Gene Related to Non-Insulin-dependent Diabetes Mellitus and Juvenile Hypertension in the Czech Population?a.
- Author
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BENDLOVÁ, B., MAZURA, I., VČELÁK, J., PERUŠIČOVÁ, J., PALYZOVÁ, D., KLIMEŠ, I., and ŠEBÖKOVÁ, E.
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- 1997
- Full Text
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45. New Multiple Somatic Mutations in the RETProto-oncogene Associated with a Sporadic Medullary Thyroid Carcinoma
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Dvoáková, Š., Václavíková, E., Sýkorová, V., Dušková, J., Vlek, P., Ryška, A., Novák, Z., and Bendlová, B.
- Abstract
Medullary thyroid carcinoma (MTC) occurs mostly as a sporadic tumor or in connection with inherited cancer syndromes—multiple endocrine neoplasia (MEN) types 2A and 2B and familial MTC. Germline mutations in the RETproto-oncogene are found in most of the familial cases. Somatic mutations in the RETproto-oncogene are detected in 23%–69% of patients with sporadic MTC. The most frequent somatic mutation is Met918Thr in exon 16 and only a small percentage of mutations in other RETexons have been observed. In a very few cases double mutations were found. Genetic screening for somatic mutations in RETexons 10, 11, 13, 14, 15, and 16 in Czech patients with sporadic MTC was carried out by DNA sequencing. This study presents a new triplesomatic mutation Gly911Asp, Met918Thr, and Glu921Lys in exon 16 of the RETproto-oncogene detected in an 18-year-old Czech male patient. In the second case, a new double-somatic mutation Val591Ile in exon 10 with a concomitant somatic mutation Met918Thr in exon 16 was found in a 77-year-old Czech female patient. These both newly described somatic multiple mutations were revealed in a hemizygous status, the loss of heterozygosity in tumor tissues in comparison with germline DNA was confirmed.
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- 2006
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46. Screening of six risk exons of the RETproto-oncogene in families with medullary thyroid carcinoma in the Czech Republic
- Author
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Jindřichová, Š, Včelák, J, Vlček, P, Neradilová, M, Němec, J, and Bendlová, B
- Abstract
Medullary thyroid carcinoma (MTC) occurs as a sporadic form (75%) or as an autosomal dominant inherited familial disorder (25%) called familial MTC (FMTC) or as multiple endocrine neoplasia type 2 (MEN2) syndromes. Germ-line mutations in the rearranged during transfection (RET)proto-oncogene in exons 10, 11, 13, 14, 15 and 16 are known to be a cause of most of the familial forms. In this paper we report molecular genetic testing of 106 families with MTC (358 tested persons) from the Czech Republic in which we directly sequenced these six exons of the RETproto-oncogene. We detected germ-line mutations in 100% of MEN2B families (4/4 families), 90% of MEN2A families (9/10), 40% of FMTC families (4/10) and 7% of apparently sporadic MTC (6/82). Eleven different germ-line mutations were revealed. MEN2B was associated with mutation Met918 Thr in exon 16. In one MEN2B family beside this mutation the Tyr791 Phe was also found, which has not yet been reported. MEN2A was restricted to different mutations in exon 11 (codon 634). In FMTC and ‘sporadic’ MTC families the mutations in exons 10, 11, 13 and 14 were detected. The genotype/phenotype correlations are given. Genetic testing revealed germ-line mutations in 23 index patients, 24 family members and excluded them in 53 relatives.
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- 2004
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47. Association between LRP5 polymorphism and bone mass at the hip in postmenopausal women with osteoporosis
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Zajickova <ce:sup loc='post">⁎</ce:sup>, K., Novosad, P., Mazura, I., Hill, M., Zemanova, A., Zofkova, I., and Bendlova, B.
- Published
- 2009
- Full Text
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48. Endokrinní disruptory -- neviditelná hrozba -- editorial.
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Bendlová, B.
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- 2013
49. Circulating β2Microglobulin in Relation to Bone Metabolism: Implications for Bone Loss with Aging
- Author
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Zofková, I., Bahbouh, R., Bendlová, B., and Kancheva, R. L.
- Abstract
The aim of this cross-sectional study was to evaluate the relationships between circulating β2microglobulin (β2m) and bone mineral density (BMD), parameters of bone remodeling, vitamin D metabolites, parathyroid hormone (PTH), estradiol levels, and age in a group of 165 clinically healthy or osteoporotic, but otherwise normal untreated women. In this group of women, systemic β2m correlated with BMD (g/cm2) levels for total hip and Ward's triangle (r =−0.298, P< 0.0001; and r =−0.299, P< 0.0001, respectively), but only at the borderline level with BMD at the spine (r =−0.145, P= 0.0604). Serum β2microglobulin markedly correlated with age (r = 0.512, P= 0.0001). β2m levels correlated with indices of bone remodeling, as well as with serum creatinine and estradiol levels. However, after stratification of all analyses by age, body mass index, and serum 25OHD3, 1,25(OH)2D3, PTH, or estradiol levels (using standard multiple regression and stepwise forward regression models), only 25OHD3was found to be an independent predictor of BMD at the hip, including Ward's triangle, as estradiol of BMD at the spine. On the other hand, β2m was not associated with BMD at any of the measured regions. Also, no association was found between serum PTH and BMD values. Therefore, systemic β2m seems to be an indicator of bone remodeling in the course of natural skeletal aging rather than a variable independently predicting bone loss.
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- 1999
- Full Text
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50. 35th Annual Meeting of the European Association for the Study of Diabetes
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Melander, A., Olsson, J., Lindberg, G., Salzman, A., Howard, T., Stang, P., Lydick, E., Emslie-Smith, A., Boyle, D. I. R., Evans, J. M. M., Macdonald, T. M., Bain, J., Sullivan, F., Juhl, C., Pørksen, N., Sturis, J., Hollingdal, M., Pincus, S., Veldhuis, J., Dejgaard, A., Schmitz, O., Kristensen, J. S., Frandsen, K. B., Bayer, Th., Müller, P., Dunning, B. E., Paladini, S., Gutierrez, C., Deacon, R., Valentin, M., Grunberger, G., Weston, W. M., Patwardhan, R., Rappaport, E. B., Sargeant, L. A., Wareham, N. J., Khaw, K. T., Zethelius, Björn, Lithell, Hans, Hales, C. Nicholas, Berne, Christian, Lakka, H.-M., Oksanen, L., Tuomainen, T.-P., Kontula, K., Salonen, J. T., Dekker, J. M., de Boks, P., de Vegt, F., Stehouwer, C. D. A., Nijpels, G., Bouter, L. M., Heine, R. J., Bruno, G., Cavallo-Perin, P., Bargero, G., D’Errico, N., Borra, M., Macchia, G., Pagano, G., Newton, R. W., Ruta, D. A., New, J. P., Wallace, C., Roxburgh, M. A., Young, R. J., Vaughan, N. J. A., Elliott, P., Brennan, G., Devers, M., MacAlpine, R., Steinke, D., Lawson, D. H., Decallonne, B., Casteels, K., Gysemans, C., Bouillon, R., Mathieu, C., Linn, Thomas, Strate, Christine, Schneider, Kerstin, Funda, D. P., Jirsa, M., Kozáková, H., Kaas, A., Kofronová, O., Tlaskalová-Hogenová, H., Buschard, K., Wanka, H., Hartmann, A., Kuttler, B., Rasmussen, S. B., Sørensen, T. S., Markholst, H., Petersen, J. S., Karounos, D., Dyrberg, T., Mabley, J. G., Haskó, G., Szabó, C., Seissler, J., Nguyen, T. B. T., Steinbrenner, H., Scherbaum, W. A., Cipriani, R., Gabriele, A., Sensi, M., Guidobaldi, L., Pantellini, F., Cerrito, M. G., Scarpa, S., Di Mario, U., Morano, S., Ceolotto, G., Iori, E., Baritono, E., Del Prato, S., Semplicini, A., Trevisan, R., Zerbini, G., Meregalli, G., Asnaghi, V., Tentori, F., Maestroni, A., Mangili, R., Marescotti, C., Vedovato, M., Tiengo, A., Tadjieva, J., Mankovsky, B. N., Van Aken, S., Raes, A., Vande Walle, J., Matthys, D., Craen, M., Hansen, H. P., Lund, S. S., Rossing, P., Jensen, T., Parving, H.-H., Andersen, S., Tarnow, L., Hansen, B. V., Trautner, C., Haastert, B., Ennenbach, N., Willich, S., Tabák, Á. Gy., Orchard, T. J., Spranger, J., Preissner, K. T., Schatz, H., Pfeiffer, A., Cantón, A., Burgos, R., Hernández, C., Lecube, A., Mesa, J., Segura, R. M., Mateo, C., Simó, R., Fathallah, L., Greene, D. A., Obrosova, I., Gilbert, R. E., Kelly, D. J., Cox, A. J., Berka-Wilkinson, J. L., Taylor, H. R., Panagiotopoulos, S., Lee, V., Jerums, G., Cooper, M. E., Hitman, G. A., Aganna, E., Ogunkolade, W. B., Rema, M., Deepa, R., Shanthi-Rani, C. S., Barakat, K., Kumarajeewa, T. R., Cassell, P. G., McDermott, M. F., Mohan, V., Ways, K., Bursell, S., Devries, T., Woodworth, J., Alatorre, C., King, G., Aiello, L. P., Karisen, A. E., Pavlovic, D., Nielsen, K., Jensen, J., Andersen, H. U., Pociot, F., Mandrup-Poulsen, T., Eizirik, D. L., Nerup, J., Lortz, S., Tiedge, M., Lenzen, S., Lally, F. J., Bone, A. J., Darville, M. I., Ho, Y.-S., Sternesjö, J., Sandler, S., Chen, M.-C., Schuit, F., Pipeleers, D. G., Merezak, S., Hardikar, A., Hoet, J. J., Remacle, C., Reusens, B., Bréant, B., Garofano, A., Czernichow, P., Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Nakano, R., Komeda, K., Eto, K., Tobe, K., Kimura, S., Kadowaki, T., Ide, T., Murakami, K., Tsunoda, M., Mochizuki, T., Ozanne, S. E., Nave, B. T., Wang, C. L., Dorling, M. W., Petry, C. J., Koopmans, S. J., van der Bent, C., Que, I., Radder, J. K., Sebokova, E., Sana, A. K., Klimes, I., Ruderman, N., Morviducci, L., Pastore, L., Morelli, S., Sagratella, E., Zorretta, D., Buongiomo, A., Tamburrano, G., Giaccari, A., Martinenghi, Sabina, De Angelis, Gabriella Cusella, Ravasi, Flavio, Bifari, Francesco, Bordignon, Claudio, Falqui, Luca, Kessler, A., Dransfeld, O., Sasson, S., Tomas, E., Zorzano, A., Eckel, J., Thorsby, P., Rosenfalck, A. M., Kjems, L., Hanssen, K. F., Madsbad, S., Birkeland, K. I., Hamilton-Wessler, M., Markussen, J., Bergman, R. N., Melki, V., Hanaire-Broutin, H., Bessières-Lacombe, S., Tauber, J.-P., Home, P. D., Lindholm, A., Riis, A., Rosenstock, J., Schwartz, S., Clark, C., Edwards, M., Donley, D., Swift, P., Mortensen, H. B., Lynggaard, H., Hougaard, P., Cull, C. A., Neil, H. A. W., Frighi, V., Manley, S. E., Holman, R. R., Turner, R. C., Steiner, G., Davis, W. A., Weeraratna, T., Bruce, D. G., Davis, T. M. E., Vergès, B., Duvillard, L., Pont, F., Florentin, E., Gambert, Ph., Benko, B., Ljubić, S., Turk, Z., Granić, M., März, W., Wollschläger, H., Klein, G., Neiss, A., Wehling, M., Huxtable, S. J., Saker, P. J., Walker, M., Frayling, T. M., Levy, J. C., O’Rahilly, S., Hattersley, A. T., McCarthy, M. I., Orecchio, A., Giacchini, A., Dominici, R., Canettieri, G., Trinti, B., Zani, M., Andreoli, M., Sciacchitano, S., de Silva, A. M., Whitecross, K., Pasco, J., Kotowicz, M., Nicholson, G., Zimmet, P., Boyko, E. J., Collier, G. R., Frittitta, L., Pizzuti, A., Argiolas, A., Graci, S., Goldfine, I. D., Bozzali, M., Ercolino, T., Costanzo, B., Iacoviello, L., Tassi, V., Trischitta, V., Wauters, M., Rankinen, T., Mertens, I., Chagnon, M., Bouchard, C., Van Gaal, L., Sivenius, K., Valve, R., Hakkarainen, V., Niskanen, L., Laakso, M., Uusitupa, M., Beridze, N., Japaridze, M., Kurashvili, R., Dundua, M., Kebuladze, G., Kazakhashvili, N., Offley-Shore, B., Thomas, B., Ghebremeskel, K., Crawford, M., Lowy, C., Eriksson, Ulf J., Martin Simán, C., Wisse, Bert, Gittenberger-de Groot, Adriana C., Wentzel, P., Eriksson, U. J., Wender-Ożegowska, E., Drews, K., Biczysko, R., Bronisz, A., Rość, D., Graczykowska-Koczorowska, A., Kotschy, M., Sokup, A., Kohnert, K. D., Besch, W., Strese, J., Frick, U., Zander, E., Kemer, W., Škrha, J., Kvasnička, J., Kalvodová, B., Hilgertová, J., Schatteman, K., Goossens, F., Scharpé, S., De Leeuw, I., Hendriks, D., Legakis, I. N., Panayiotou, D., Mountokalakis, Th. D., Enderle, M. D., Beckmann, P., Balletshofer, B., Rittig, K., Maerker, E., Volk, A., Meisner, C., Jacob, S., Matthaei, S., Häring, H. U., Rett, K., Ueda, K., Nakagawa, T., Shimajiri, Y., Kokawa, M., Matsumoto, E., Sasaki, H., Sanke, T., Nanjo, K., McKinnon, Caroline M., Macfarlane, Wendy M., Docherty, Kevin, Furukawa, N., Shirotani, T., Kishikawa, H., Kaneko, K., Araki, E., Shichiri, M., Prentki, M., Roduit, R., Susini, S., Buteau, J., Ejrnæs, A. M., Andersen, N. Aa., Osterhoff, M., Möhlig, M., Ortmann, J., Bikashaghi, F., Mayer, C., Bikashagi, F., Ackermans, M. T., Pereira Arias, A. M., Bisschop, P. H. L. T., Endert, E., Sauerwein, H. P., Romijn, J. A., Gastaldelli, A., Baldi, S., Pettiti, M., Natali, A., Frascerra, S., Camastra, S., Toschi, E., Ferrannini, E., Stingl, H., Krssak, M., Bischof, M. G., Krebs, M., Fürnsinn, C., Nowotny, P., Waldhäusl, W., Roden, M., Neeft, M., Meijer, A. J., Båvenholm, P., Pigon, J., Efendic, S., Kästenbauer, T., Sauseng, S., Sokol, G., Auinger, M., Irsigler, K., Abbott, C. A., Carrington, A. L., Faragher, B., Kulkarni, J., Van Ross, E. R. E., Boulton, A. J. M., Armstrong, D. G., Hadi, S., Nguyen, H. C., Harkless, L. B., Jirkovská, A., Kasalicky, P., Hosová, J., Skibova, J., Uccioli, L., Caselli, A., Giacomozzi, C., Macellari, V., Giurato, L., Lardieri, L., Menzinger, G., Pham, H. T., Rosenblum, B. I., Lyons, T. E., Giurini, J. M., Smakowski, P., Chrzan, J. S., Habershaw, G. M., Veves, A., Foster, A. M., Bates, M., Doxford, M., Edmonds, M. E., Kecha, O., Winkler, R., Martens, H., Collette, J., Lefèbvre, P. J., Greiner, D., Geenen, V., Atlan-Gepner, C., Naspetti, M., Valéro, R., Barad, M., Lepault, F., Vialettes, B., Naquet, P., de Galan, B., Netea, M. G., Hancu, N., Smits, P., Van der Meer, J. W. M., Osterbye, T., Jørgensen, K. H., Tranum-Jensen, J., Fredman, P., Høy, M., Bokvist, K., Olsen, H. L., Horn, T., Gromada, J., Laub, R., Lohmann, T., Hahn, H. J., Adler, T., Emmrich, F., Rabuazzo, A. M., Lupi, R., Dotta, F., Patanè, G., Marselli, L., Realacci, M., Piro, S., Del Guerra, S., Santangelo, C., Navalesi, R., Purrello, F., Marchetti, P., de Vos, P., Visser, L., de Haan, B. J., Klok, P., van Schilfgaarde, R., Poppema, S., Juang, J.-H., Kuo, C.-H., Hsu, B. R.-S., Nacher, V., Pérez, M., Biarnés, M., Raurell, M., Soler, J., Montanya, E., Ritzel, R., Maubach, J., Büsing, M., Becker, T., Klempnauer, J., Hücking, K., Schmiegel, W. H., Nauck, M. A., Bouček, P., Saudek, F., Adamec, M., Kožitarová, R., Jedináková, T., Vlasáková, Z., Skibová, J., Bartoš, V., Maffi, P., Bertuzzi, F., Aldrighetti, L., Taglietti, M. V., Castelnuovo, A., Pozza, G., Di Carlo, V., Secchi, A., Renier, G., Mamputu, J.-C., Gillespie, J. S., McMaster, D., Mercer, C., Trimble, E. R., Lecomte, M., Véricel, E., Paget, C., Ruggiero, D., Lagarde, M., Wiernsperger, N., Pricci, F., Leto, G., Amadio, L., Cordone, S., Iacobini, C., Catalano, S., Violi, F., Rotella, C. M., Pugliese, G., Zicari, A., Gradini, R., Sale, P., Pala, L., Cresci, B., Giannini, S., Manuelli, C., Dahlfors, G., Arnqvist, H. J., Gonelle-Gispert, C., Halnan, P. A., Sadoul, K., Wolter, S., Lang, J., Niwa, T., Yu, W., Hidaka, H., Senda, T., Niki, I., Fukasawa, T., Renstrom, E., Barg, S., Seward, E., Rorsman, P., Rutter, G. A., Molinete, M., Lilla, V., Ravazzola, M., Halban, P. A., Efanov, A. M., Bertorello, A. M., Zaitsev, S. V., Zwiller, J., Berggren, P.-O., MŞengül, A., Salman, F., Sargrn, M., Özer, E., Karşidaǧ, K., Salman, S., Gedik, S., Satman, İ., Dinççaǧ, N., Yılmaz, M. T., Lloyd, A., Hopkinson, P. K., Testa, M. A., Blonde, L., Turner, R. R., Hayes, J., Simonson, D. C., van der Ven, N. C. W., Lubach, C. H. C., Snoek, F. J., Mollema, E. D., van der Ploeg, H. M., Danne, T., Hoey, H., McGee, H., Fitzgerald, H., Lernmark, B., Thernlund, G., Fredin, K., Hägglöf, B., Lugari, R., Dell’Anna, C., Ugolotti, D., Dei Cas, A., Barilli, A. L., Sard, L., Marani, B., Iotti, M., Zandomeneghi, R., Gnudi, A., Kjems, L. L., Volund, Aa., Toft-Nielsen, M., Damholt, M. B., Hilsted, L., Hughes, T. E., Krarup, T., Holst, J. J., Young, A., Gottlieb, A., Fineman, M., Kolterman, O., Cancelas, J., García-Martínez, J. A., Villanueva-Peñacarrillo, M. L., Valverde, I., Malaisse, W. J., Filipsson, K., Ahrén, B., Balkan, B., Kwasnik, L., Battle, B., Li, X., Egan, J. M., Clocquet, A. R., Elahi, D., Petrella, E., Pricket, K., Petersen, K. F., Sullivan, J. T., Amatruda, J. M., Livingston, J. N., Shulman, G. I., Freyse, E.-J., Knospe, S., Glund, K., Demuth, H.-U., Walker, D., Malik, R. A., Reljanovic, M., Barada, A., Milicevic, Z., Tack, Cees J., Goldstein, David S., Van Huysen, C., Stevens, M. J., Cao, X., Sundkvist, G., Dahlin, L.-B., Eriksson, K.-F., Rosén, I., Lattimer, S. A., Sima, A. A. F., Sullivan, K., Shaw, J. E., de Courten, M. P., Zimmet, P. Z., Gourdy, P., Ruidavets, J. B., Arveiler, D., Amouyel, Ph., Bingham, A., Tauber, J. P., Lam, K. S. L., Wat, N. M. S., Lam, T. H., Janus, E. D., de Pablos, P., Rodriguez, F., Martínez, J., Sánchez, V., Santana, C., García, I., Macías, A., Levin, K., Hother-Nielsen, O., Henriksen, J. E., Beck-Nielsen, H., Brechtel, K., Machann, J., Koch, M., Nielsen, M., Löblein, K., Becker, R., Denignger, M., Renn, W., Machicao, F., Claussen, C. D., Schick, F., Diraison, F., Moulin, P., Beylot, M., Thams, P., Capito, K., Eliasson, Lena, Barg, Sebastian, Göpel, Sven, Kanno, Takahiro, Renström, Erik, Meda, P., Charollais, A., Gjnovci, A., Calabrese, A., Wonkam, A., Caton, D., Wisznievski, L., Serre, V., Cogne, F., Bauquis, J., Bosco, D., Huarte, J., Herrera, P., Gotfredsen, C. F., Vessby, B., Manuel y Keenoy, B., Engelen, W., Vertommen, J., Schrans, S., Louheranta, A., Lindström, J., Tuomilehto, J., Segal, K. R., Heymsfield, S., Hauptman, J., Boldrin, M., Lucas, C., Pandolfi, A., Cetrullo, D., Polishchuck, R., Alberta, M., Pellegrini, G., Calafiore, A., Vitacolonna, E., Capani, F., Consoli, A., Halleux, C. M., Gillot, E. F., Brichard, S. M., Van der Planken, M., Corthouts, B., Peiffer, F., Scholten, D., Walke, M., Assert, R., Pirags, V., Pedula, K. L., Hillier, T. A., Brown, J. B., Santini, S. A., Marra, G., Cotroneo, P., Manto, A., Di Leo, M. A. S., Di Gregorio, S., Tordi, A., Pitocco, D., Ruotolo, V., Ghirlanda, G., Temelkova-Kurktschiev, T., Schaper, F., Koehler, C., Henkel, E., Hanefeld, M., Mancini, L., Citterio, F., Cotroneo, A., Ceroone, S., Castagneto, M., Rajbhandari, S. M., Dent, M. T., Plater, M. E., Harris, N. D., Tesfaye, S., Ward, J. D., Dupuy, O., Mayaudon, H., Lecoules, S., Bauduceau, B., Palou, M., Farret, O., Molinié, C., Antonelli-Incalzi, R., Fuso, L., Giordano, A., Calcagni, M. L., Todaro, L., Basso, S., Tramaglino, L. M., Troncone, L., Pistelli, R., Guillot, R., Bringuier, A., Porokhov, B., Guillausseau, P. J., Feldmann, G., Zivanic, S., Cizmic, M., Dragojevic, R., Vanovic, M., Borghouts, L. B., van Kranenburg, G. P. J., Schaart, G., Keizer, H. A., Niess, A. M., Dickuth, H. H., Lutz, O., Barbe, P., Calazel-Fournier, C., Hernandez, G., Saint-Martin, F., Galitzky, J., Gonçalves, A. A., da Silva, E. C., Brito, I. J. L., da Silva, C. A., Lawrence, N. J., Kousta, E., Mulnier, H., Penny, A., Millauer, B., Johnston, D. G., Robinson, S., Perriello, G., Pimenta, W., Pampanelli, S., Lucidi, P., Lepore, M., Porcellati, F., Cordoni, M. C., De Feo, P., Bolli, G. B., Sjöstrand, M., Holmäng, A., Lönnroth, P., Hauer, B., Grauer, P., Artzner, S., Lang, R., Stumvoll, M., Monti, L. D., Piatti, P. M., Gemone, F., Valsecchi, G., Magni, M., Barbieri, E., Setola, E., Sandoli, E. P., Galli-Kienle, M., Pontiroli, A. E., Nichols, Gregory A., Brown, Jonathan B., Salzsieder, E., Boltz, H., Ramirez, J. C., Rutscher, A., Fischer, U., Koenig, Ch., Friske, M., Schramm, W., Landgraf, R., Bachmann, W., Bangemann, M., Groeneveld, G., Edvell, Anders, Lindström, Per, Tsiotra, P., Koukourava, A., Raptis, S. A., Tsigos, C., Boutou, E., Triandaffilopoulou, A., Egido, E. M., Rodríguez-Gallardo, J., Gutiérrez, E., García, P., Silvestre, R. A., Marco, J., Khan, Akhtar, Ling, Zong-Chao, Ahren, Bo, Efendic, Suad, Bünting, C., Du, X., Zhi Sui, G., Rösen, P., Koschinsky, T., Kearney, T. M., Sharp, P. S., Lapolla, A., Fedele, D., Martano, L., Garbeglio, M., Seraglia, R., Favretto, D., Traldi, P., Meerwaldt, R., Smit, A. J., Links, Th. P., v. Roon, A. M., Graaf, R., Gans, R. O. B., Deynelİ, O., Ersöz, H. Ö., Gogas, D., Fak, A. 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