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Esophageal granular cell tumors (GCTs), or also called Abrikossoff's tumor are rare benign tumors originating from Schwann cells most commonly found in the skin, subcutaneous tissue, and tongue. Approximately 5% -8% arise in the gastrointestinal tract, and one-third of these tumors arise in the esophagus [1]. This neoplasm has a benign behavior usually, but there have been described a malignant transformation in 2% -3% of the cases. Herein, we discuss a case of a 70-year-old male patient with no pathological background, admitted for dysphagia evolving in 3 months that was explored with endoscopy and CT, the diagnosis at this level was challenging but the histopathology and Immunohistochemistry confirmed the presence of granular cells thus confirm the diagnosis. The purpose of our work is to report the uncommon evolution of an Abrikossoff 's tumor located in the esophagus, as a warning of the possible malignant transformation of this tumor mostly benign; also we made a review of the literature., (© 2021 Published by Elsevier Inc. on behalf of University of Washington.)

Optic nerve tuberculoma is a rare extra-pulmonary manifestation of mycobacterial infection. It is usually associated with HIV infected patients. Due to its clinical polymorphism, the diagnosis and management of the disease either in immunocompetent patients and immunocompromised ones remains challenging. Herein, we discuss a case of a 32-year-old patient with no history of immunodeficiency admitted for multifocal tuberculosis with a reduced visual acuity as an extra-pulmonary manifestation, and radiologically revealed the presence of tuberculoma in the optic nerve in the cerebral MRI., (© 2021 Published by Elsevier Inc. on behalf of University of Washington.)