20 results on '"Bemt, E.A.J.M. van den"'
Search Results
2. Pragmatic trial on inhaled corticosteroid withdrawal in patients with COPD in general practice
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Bemt, E.A.J.M. van den, Nieuwenhof, L. van den, Rutjes, A.W., Meer, Victor van der, Stege, Gerben, Wensing, M.J.P., Teichert, M., Schermer, T.R.J., Bemt, E.A.J.M. van den, Nieuwenhof, L. van den, Rutjes, A.W., Meer, Victor van der, Stege, Gerben, Wensing, M.J.P., Teichert, M., and Schermer, T.R.J. more...
- Abstract
Contains fulltext : 226130.pdf (publisher's version ) (Open Access)
- Published
- 2020
Catalog
3. Multicomponent staging indices for chronic obstructive pulmonary disease in daily patient care: what's the yield?
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Bemt, E.A.J.M. van den and Schermer, T.R.J.
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Poverty-related infectious diseases [N4i 3] ,Effective primary care and public health [NCEBP 7] - Abstract
Contains fulltext : 89290.pdf (Publisher’s version ) (Closed access) 01 oktober 2010
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- 2010
4. The Pelican Project. Meeting the needs of children with asthma
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Weel, C. van, Bemt, E.A.J.M. van den, Merkus, P.J.F.M., Schermer, T.R.J., Bragt, S.T.W.M. van, Weel, C. van, Bemt, E.A.J.M. van den, Merkus, P.J.F.M., Schermer, T.R.J., and Bragt, S.T.W.M. van
- Abstract
Radboud Universiteit Nijmegen, 19 oktober 2015, Promotor : Weel, C. van Co-promotores : Bemt, E.A.J.M. van den, Merkus, P.J.F.M., Schermer, T.R.J., Contains fulltext : 144031.pdf (publisher's version ) (Open Access), The thesis, called ‘Pelican Project: Meeting the Needs of Children with asthma’ describes the importance of including personal treatment goals of children in the care of asthma. Through a health-related quality of life questionnaire, called ‘the Pelican instrument’, the treatment goals for children are measured. This online tool can be completed by children independently at home before they come to consult their GP or pediatrician. In general, it appeared that the Pelican instrument reliability and valid quality of life measurement tool in a Dutch population of children with asthma between 6 and 12 years. The first study of personalized treatment based on the Pelican instrument was performed within nine general practices. Unfortunately, this study did not have enough participants to deliver sufficient evidence to determine whether the treatment is effective in improving quality of life in children asthma. Although further research on patient-centered care is needed in primary care, the question arises whether there is a need for such treatment and whether the current conditions in the Dutch primary care are favorable. In a second RCT in a Dutch population of children with asthma treated in the specialized health care, no significant differences were found between usual care and patient-centered care after adjusted analyses with primary and secondary outcome measures, with the exception of lung function. Finally, the researchers have concluded that, although there was no statistically significant improvement in the health-related quality of life in children with asthma, a relevant part of the children of clinical improvement in the treatment group showed in comparison to the usual care. After an evaluation of the process of care, it was found that the treatment based on the Pelican instrument shows potential to be feasible and acceptable in specialized care. However, there was room for improvement left in patient-centered working by nurses with regard to problem sele more...
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- 2015
5. Budesonide in preschool-age children with recurrent wheezing
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Bemt, E.A.J.M. van den and Nieuwenhof, L. van den
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Effective primary care and public health [NCEBP 7] - Abstract
Item does not contain fulltext
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- 2012
6. Obesity: another good reason to question the fixed FEV1/FVC ratio when diagnosing COPD
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Bemt, E.A.J.M. van den and Schermer, T.R.J.
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Effective primary care and public health [NCEBP 7] - Abstract
Item does not contain fulltext 01 februari 2012
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- 2012
7. The Asthma Control Questionnaire for children: still more questions than answers
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Bemt, E.A.J.M. van den, Bragt, S.T.W.M. van, and Schermer, T.R.J.
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Effective primary care and public health [NCEBP 7] - Abstract
Item does not contain fulltext 01 juni 2011
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- 2011
8. Monitoring patients with COPD in primary care
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Bemt, E.A.J.M. van den, Weel, C. van, Grol, R.P.T.M., Smeele, I.J.M., Schermer, T.R.J., and Radboud University Nijmegen
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Effective primary care and public health [NCEBP 7] ,GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries) - Abstract
Contains fulltext : 74659.pdf (Publisher’s version ) (Open Access) RU Radboud Universiteit Nijmegen, 23 november 2009 Promotores : Weel, C. van, Grol, R.P.T.M. Co-promotores : Smeele, I.J.M., Schermer, T.R.J. 165 p. more...
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- 2009
9. Megatrials for Bronchodilators in Chronic Obstructive Pulmonary Disease (COPD) Treatment: Time to Reflect
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Dijk, W.D. van, Bemt, E.A.J.M. van den, Weel, C. van, Dijk, W.D. van, Bemt, E.A.J.M. van den, and Weel, C. van
- Abstract
Contains fulltext : 118792.pdf (publisher's version ) (Open Access), Introduction: Chronic obstructive pulmonary disease (COPD) is an important cause of morbidity and mortality worldwide. Although (long-acting) bronchodilators are used to relieve symptoms, the impact of bronchodilators on COPD mortality remains an unresolved issue. Our aim was to explore the results and the interpretations of the results of studies of bronchodilator treatment from high-impact COPD trials. METHODS: We searched PubMed and Embase for primary publications of randomized controlled trials with more than 1000 participants with COPD and that studied the effectiveness of long-acting bronchodilator treatment. We assessed population characteristics, primary outcomes, focus of outcomes, and possible bias from concomitant pulmonary medication. RESULTS: We retrieved 5 primary publications of large trials. Participants tended to be patients with rather severe COPD who were cared for at a hospital. Only half of the primary outcomes were statistically significant. Reports tended to focus on statically significant outcomes and not necessarily on primary outcomes or outcomes of the whole study population. The relevance of study outcomes was rarely discussed. Discussion: The rather small effects of bronchodilators in a COPD population that is not representative for daily care, together with the tendency of relying on statistical rather than clinical significance, hampers translation to the large number of patients with COPD in the community. more...
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- 2013
10. The clinical utility of prognostic indices: the proof of the pudding is in the eating.
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Dijk, W.D. van, Bemt, E.A.J.M. van den, Weel, C. van, Dijk, W.D. van, Bemt, E.A.J.M. van den, and Weel, C. van
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Item does not contain fulltext
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- 2012
11. PELICAN: A quality of life instrument for childhood asthma: Study Protocol of two Randomized Controlled Trials in Primary and Specialized Care in the Netherlands
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van Bragt, S., Bemt, E.A.J.M. van den, Thoonen, B., Weel, C. van, Merkus, P., Schermer, T.R.J., van Bragt, S., Bemt, E.A.J.M. van den, Thoonen, B., Weel, C. van, Merkus, P., and Schermer, T.R.J.
- Abstract
Contains fulltext : 108946.pdf (publisher's version ) (Open Access), BACKGROUND: Asthma is one of the major chronic health problems in children in the Netherlands. The Pelican is a paediatric asthma-related quality of life instrument for children with asthma from 6-11 years old, which is suitable for clinical practice in primary and specialized care. Based on this instrument, we developed a self-management treatment to improve asthma-related quality of life. The Pelican intervention will be investigated in different health care settings. Results of intervention studies are often extrapolated to other health care settings than originally investigated. Because of differences in organization, disease severity, patient characteristics and care provision between health care settings, extrapolating research results could lead to unnecessary health costs without the desired health care achievements. Therefore, interventions have to be investigated in different health care settings when possible. This study is an example of an intervention study in different health care settings. In this article, we will present the study protocol of the Pelican study in primary and specialized care. METHOD/DESIGN: This study consists of two randomized controlled trials to assess the effectiveness of the Pelican intervention in primary and specialized care. The trial in primary care is a multilevel design with 170 children with asthma in 16 general practices. All children in one general practices are allocated to the same treatment group. The trial in specialized care is a multicentre trial with 100 children with asthma. Children in one outpatient clinic are randomly allocated to the intervention or usual care group. In both trials, children will visit the care provider four times during a follow-up of nine months. This study is registered and ethically approved. DISCUSSION: This article describes the study protocol of the Pelican study in different health care settings. If the Pelican intervention proves to be effective and efficient, implementati more...
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- 2012
12. Multidimensional prognostic indices for use in COPD patient care. A systematic review.
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Dijk, W.D. van, Bemt, E.A.J.M. van den, Haak-Rongen, S., Bischoff, E.W.M.A., Weel, C. van, Veen, J.C. In 't, Schermer, T.R.J., Dijk, W.D. van, Bemt, E.A.J.M. van den, Haak-Rongen, S., Bischoff, E.W.M.A., Weel, C. van, Veen, J.C. In 't, and Schermer, T.R.J. more...
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Contains fulltext : 98117.pdf (publisher's version ) (Open Access), BACKGROUND: A growing number of prognostic indices for chronic obstructive pulmonary disease (COPD) is developed for clinical use. Our aim is to identify, summarize and compare all published prognostic COPD indices, and to discuss their performance, usefulness and implementation in daily practice. METHODS: We performed a systematic literature search in both Pubmed and Embase up to September 2010. Selection criteria included primary publications of indices developed for stable COPD patients, that predict future outcome by a multidimensional scoring system, developed for and validated with COPD patients only. Two reviewers independently assessed the index quality using a structured screening form for systematically scoring prognostic studies. RESULTS: Of 7,028 articles screened, 13 studies comprising 15 indices were included. Only 1 index had been explored for its application in daily practice. We observed 21 different predictors and 7 prognostic outcomes, the latter reflecting mortality, hospitalization and exacerbation. Consistent strong predictors were FEV1 percentage predicted, age and dyspnoea. The quality of the studies underlying the indices varied between fairly poor and good. Statistical methods to assess the predictive abilities of the indices were heterogenic. They generally revealed moderate to good discrimination, when measured. Limitations: We focused on prognostic indices for stable disease only and, inevitably, quality judgment was prone to subjectivity. CONCLUSIONS: We identified 15 prognostic COPD indices. Although the prognostic performance of some of the indices has been validated, they all lack sufficient evidence for implementation. Whether or not the use of prognostic indices improves COPD disease management or patients' health is currently unknown; impact studies are required to establish this. more...
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- 2011
13. How does asthma influence the daily life of children? Results of focus group interviews.
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Bemt, E.A.J.M. van den, Kooijman, S., Linssen, V., Lucassen, P.L.B.J., Muris, J., Slabbers, G., Schermer, T.R.J., Bemt, E.A.J.M. van den, Kooijman, S., Linssen, V., Lucassen, P.L.B.J., Muris, J., Slabbers, G., and Schermer, T.R.J. more...
- Abstract
Contains fulltext : 88307.pdf (publisher's version ) (Open Access), BACKGROUND: Health-related quality of life (HRQL) brings together various aspects of an individual's subjective experience that relate both directly and indirectly to health, disease, disability, and impairment. Although asthma is the most common chronic disease in childhood, information on pediatric patients' views on asthma-specific HRQL has not been described before. The aim of this study was to establish the components of asthma-specific HRQL, as experienced by primary school-aged asthmatic children. The generated components will be used to develop an individualized HRQL instrument for childhood asthma. METHODS: Primary school-aged asthmatic children were invited to participate in three consecutive focus group sessions. A total of five focus groups were formed. Two reviewers independently 1) identified trends in the statements and relations between HRQL components, 2) clustered the components into a small number of domains and, 3) made a model on asthma-specific HRQL based on the transcribed statements of the children. The results were compared between the two reviewers and resulted in a final model. RESULTS: Asthma influenced the life of the children physically, emotionally and socially. The most important components of HRQL were the effects on, and consequences of asthma on peer relationships (e.g., being bullied), the dependence on medication, shortness of breath, cough, limitations in activities and limitations due to the response on cigarette smoke exposure. CONCLUSION: The outcome of the focus group meetings indicates that asthma influences the life of children in various ways. Not all essential components of HRQL, according to the children, are part of existing asthma-specific HRQL instruments. more...
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- 2010
14. Low body mass index, airflow obstruction, and dyspnoea in a primary care COPD patient population.
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Bemt, E.A.J.M. van den, Smeele, I.J.M., Kolkman, M., Grol, R.P.T.M., Weel, C. van, Schermer, T.R.J., Bemt, E.A.J.M. van den, Smeele, I.J.M., Kolkman, M., Grol, R.P.T.M., Weel, C. van, and Schermer, T.R.J. more...
- Abstract
1 juni 2010, Contains fulltext : 87306.pdf (publisher's version ) (Closed access), AIM: The objective of our study was to explore the existence/co-existence of factors - as per American Thoracic Society (ATS)/European Respiratory Society (ERS) standards - for staging patients in a primary care COPD population. METHOD: A representative sample of COPD patients in primary care was studied. Cross-sectional information on airflow obstruction, body mass index (BMI), and dyspnoea (Modified Medical Research Council [MMRC] score) were collected. The existence/co-existence of these prognostic factors is described. RESULTS: The study sample consisted of 2,023 patients. BMI was low in 11.7%, MMRC score > or =2 was found in 28.7%, and 53.9% fulfilled the criteria of relevant airflow obstruction. Only 3.4% of this population scored on all three prognostic factors. CONCLUSION: Moderate dyspnoea and moderate airflow obstruction were rather prevalent in this primary care population, but coexistence of factors was low. Therefore, it seems that the assessment of BMI and dyspnoea represent additional information on primary care COPD patients. more...
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- 2010
15. Monitoring patients with COPD in primary care.
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Weel, C. van, Grol, R.P.T.M., Smeele, I.J.M., Schermer, T.R.J., Bemt, E.A.J.M. van den, Weel, C. van, Grol, R.P.T.M., Smeele, I.J.M., Schermer, T.R.J., and Bemt, E.A.J.M. van den
- Abstract
RU Radboud Universiteit Nijmegen, 23 november 2009, Promotores : Weel, C. van, Grol, R.P.T.M. Co-promotores : Smeele, I.J.M., Schermer, T.R.J., Contains fulltext : 74659.pdf (publisher's version ) (Open Access) more...
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- 2009
16. An expert-supported monitoring system for patients with chronic obstructive pulmonary disease in general practice: results of a cluster randomised controlled trial.
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Bemt, E.A.J.M. van den, Schermer, T.R.J., Smeele, I.J.M., Boonman-de Winter, L., Boxem, T.J. van, Denis, J., Grootens-Stekelenburg, J.G., Grol, R.P.T.M., Weel, C. van, Bemt, E.A.J.M. van den, Schermer, T.R.J., Smeele, I.J.M., Boonman-de Winter, L., Boxem, T.J. van, Denis, J., Grootens-Stekelenburg, J.G., Grol, R.P.T.M., and Weel, C. van more...
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Contains fulltext : 80010.pdf (publisher's version ) (Open Access)
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- 2009
17. Factoren geassocieerd met de concentratie huisstofmijtallergenen op het matras.
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Bemt, E.A.J.M. van den, Vries, M.P. de, Knapen, L. van, Jansen, M., Goossens, M.E.J.B., Muris, J.W.M., Schayck, C.P. van, Bemt, E.A.J.M. van den, Vries, M.P. de, Knapen, L. van, Jansen, M., Goossens, M.E.J.B., Muris, J.W.M., and Schayck, C.P. van more...
- Abstract
Contains fulltext : 49321.pdf (publisher's version ) (Closed access)
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- 2006
18. Factors associated with asthma control.
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Vries, M.P. de, Bemt, E.A.J.M. van den, Lince, S.L., Muris, J.W.M., Thoonen, B.P.A., Schayck, C.P. van, Vries, M.P. de, Bemt, E.A.J.M. van den, Lince, S.L., Muris, J.W.M., Thoonen, B.P.A., and Schayck, C.P. van more...
- Abstract
Contains fulltext : 48477.pdf (publisher's version ) (Closed access), The aim of this study was to evaluate which factors are associated with asthma control experienced by asthma patients. In a cross-sectional study patients aged 16-60 years with mild to moderate asthma were selected. The influence of the following factors on asthma control was studied in a multivariate model: age, gender, socioeconomic status, smoking, perceived hyperresponsiveness (PHR, responding with asthma symptoms to one or more triggers), allergy (Phadiatop), long-acting bronchodilating agents, and inhaled corticosteroids. Asthma control was measured by means of the Asthma Control Questionnaire (ACQ) as developed by Juniper. Forced expiratory volume in 1 second (FEV1) was measured by means of a portable spirometer. In this study with 311 patients, mean ACQ score was 1.39 (range 0-4.43). A stepwise backward linear regression analysis showed that low socioeconomic status (beta 0.425; p=0.001), current smoking (beta 0.555; p<0.001), high dose of inhaled corticosteroids (beta 0.364; p=0.04) and perceived hyperresponsiveness for increasing number of different triggers (PHR for 1 trigger beta 0.833; p=0.03; 2 triggers beta 0.810; p=0.03; 3 triggers beta 0.995; p=0.01; 4 triggers beta 1.131; p=0.002; 5 triggers beta 1.182; p=0.002) are independent predictors for poorer asthma control. Beside treatment with medication, stopping smoking and avoidance of triggers are factors, which may have a high impact on asthma control. more...
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- 2005
19. Clinical effectiveness of a mite allergen-impermeable bed-covering system in asthmatic mite-sensitive patients.
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Bemt, E.A.J.M. van den, Knapen, L. van, Vries, M.P. de, Jansen, M., Cloosterman, S.G.M., Schayck, C.P. van, Bemt, E.A.J.M. van den, Knapen, L. van, Vries, M.P. de, Jansen, M., Cloosterman, S.G.M., and Schayck, C.P. van more...
- Abstract
Contains fulltext : 58660.pdf (publisher's version ) (Closed access), BACKGROUND: Exposure to allergens plays a role in the development of bronchial hyperresponsiveness and in the chronic inflammatory response seen in asthmatic patients. House dust mites (HDMs) are an important source of allergen. Reduction of these allergens might lead to better lung function and reduction of asthma symptoms. OBJECTIVE: The effect of HDM-impermeable covers on HDM allergen levels, peak flow values, and asthma symptoms were measured. Therefore a randomized clinical trial was carried out. METHODS: Fifty-two allergic asthmatic patients were randomly allocated to use the HDM-impermeable or placebo covers. During the study period, daily peak flow and asthma symptom scores were recorded. Dust samples were taken from the mattresses. RESULTS: We observed a significant reduction in HDM allergen levels on the mattresses after encasing them with HDM-impermeable covers (reduction of 87% of Der p 1 in micrograms per gram of dust; P <.001). Baseline symptoms were so low that no improvement could be established. Morning peak expiratory flow is significantly higher in the intervention group compared with that seen in the placebo group during the study period (beta=20.2; P <.01). CONCLUSIONS: HDM-impermeable covers significantly decreased the level of HDM allergens. Furthermore, morning peak flow was significantly increased during the intervention period. This study indicates that HDM allergen-avoidance measures might have beneficial effects on allergen reduction and asthma outcome. more...
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- 2004
20. The Pelican Project. Meeting the needs of children with asthma
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Bragt, S.T.W.M. van, Weel, C. van, Bemt, E.A.J.M. van den, Merkus, P.J.F.M., Schermer, T.R.J., and Radboud University Nijmegen
- Subjects
Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] - Abstract
Contains fulltext : 144031.pdf (Publisher’s version ) (Open Access) The thesis, called ‘Pelican Project: Meeting the Needs of Children with asthma’ describes the importance of including personal treatment goals of children in the care of asthma. Through a health-related quality of life questionnaire, called ‘the Pelican instrument’, the treatment goals for children are measured. This online tool can be completed by children independently at home before they come to consult their GP or pediatrician. In general, it appeared that the Pelican instrument reliability and valid quality of life measurement tool in a Dutch population of children with asthma between 6 and 12 years. The first study of personalized treatment based on the Pelican instrument was performed within nine general practices. Unfortunately, this study did not have enough participants to deliver sufficient evidence to determine whether the treatment is effective in improving quality of life in children asthma. Although further research on patient-centered care is needed in primary care, the question arises whether there is a need for such treatment and whether the current conditions in the Dutch primary care are favorable. In a second RCT in a Dutch population of children with asthma treated in the specialized health care, no significant differences were found between usual care and patient-centered care after adjusted analyses with primary and secondary outcome measures, with the exception of lung function. Finally, the researchers have concluded that, although there was no statistically significant improvement in the health-related quality of life in children with asthma, a relevant part of the children of clinical improvement in the treatment group showed in comparison to the usual care. After an evaluation of the process of care, it was found that the treatment based on the Pelican instrument shows potential to be feasible and acceptable in specialized care. However, there was room for improvement left in patient-centered working by nurses with regard to problem selection and goal setting. Further research into the cost-effectiveness is recommended before the examined person-centered care is entered in pediatric outpatient clinics in the Netherlands. Radboud Universiteit Nijmegen, 19 oktober 2015 Promotor : Weel, C. van Co-promotores : Bemt, E.A.J.M. van den, Merkus, P.J.F.M., Schermer, T.R.J. more...
- Published
- 2015
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