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12. Changes in ventilator strategies and outcomes in preterm infants

Author

Vendettuoli, Valentina, Bellù, Roberto, Zanini, Rinaldo, Mosca, Fabio, Gagliardi, Luigi, Turoli, D, Weissmann, G, De Nisi, G, Barbarini, M, Villa, E, Franco, C, Fasolato, V, Contiero, MR, Cattarossi, L, Ellero, S, Tagliabue, P, Abbiati, L, Fabris, C, Prandi, G, Vielmi, F, Agosti, M, Tandoi, F, De Curtis, M, Lucchini, R, Ferrari, F, Gallo, C, Bellante, E, Boccacci, S, Latini, G, Giannuzzi, R, Martinelli, S, Brunelli, A, Di Nunzio, ML, Filippone, M, Carli, G, Ancora, G, Mammoliti, P, Gancia, GP, Dalmazzo, C, Messina, F, Magaldi, R, Rinaldi, M, Lago, P, Saia, OS, Visentin, S, Presta, G, Cella, D, Poggiani, C, Ferrari, D, Barera, G, Bove, M, Burgio, G, Sala, E, Barberi, I, Tiralongo, V, Faldella, G, Grandi, S, and Cimatti, AG

Published
2014
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16. Acute Rheumatic Fever: Where Do We Stand? An Epidemiological Study in Northern Italy

Author

Marino, Achille, primary, Cimaz, Rolando, additional, Pelagatti, Maria Antonietta, additional, Tattesi, Giulia, additional, Biondi, Andrea, additional, Menni, Laura, additional, Sala, Marco, additional, Calzi, Patrizia, additional, Morandi, Francesco, additional, Cortinovis, Francesca, additional, Cogliardi, Anna, additional, Addis, Claudia, additional, Bellù, Roberto, additional, Andreotti, Massimo, additional, and Varisco, Tiziana, additional

Published
2021
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21. Additional file 2 of Managerial features and outcome in neonatal intensive care units: results from a cluster analysis

Author

Fanelli, Simone, Bellù, Roberto, Zangrandi, Antonello, Gagliardi, Luigi, and Zanini, Rinaldo

Subjects
health care facilities, manpower, and services
Abstract

Additional file 2. Questionnaire administered to nursing staff, Questionnaire administered to nursing staff who had been working in the NICU for at least 3 months in order to measure the working environment.

Published
2020
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22. Additional file 1 of Managerial features and outcome in neonatal intensive care units: results from a cluster analysis

Author

Fanelli, Simone, Bellù, Roberto, Zangrandi, Antonello, Gagliardi, Luigi, and Zanini, Rinaldo

Abstract

Additional file 1. Questionnaire administered to medical staff, Questionnaire administered to medical staff who had been working in the NICU for at least 3 months in order to identified the system used to evaluate qualitative performance and the level of staff satisfaction.

Published
2020
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29. Association of maternal hypertension and chorioamnionitis with preterm outcomes

Author

Gagliardi, Luigi, Rusconi, Franca, Bellù, Roberto, Zanini, Rinaldo, Mirri, Gianpaolo, Condò, Manuela, Turoli, Daniela, Vanzati, Mara, Mosca, Fabio, De Nisi, Giuseppe, Polacco, Paola, Villa, Elena, Barbarini, Mario, Fasolato, Valeria, Franco, Caterina, Contiero, Raffaella, Ellero, Serena, Cattarossi, Luigi, Abbiati, Laura, Borroni, Cesarina, Prandi, Giovanna, Fabris, Claudio, Vielmi, Francesca, Borgione, Silvia, Agosti, Massimo, Tandoi, Francesco, Guidali, Rosanna, De Curtis, Mario, Tozzi, Claudio, Lucchini, Renato, Battaglioli, Marina, Lista, Gian Luca, Introvini, Paola, Ferrari, Fabrizio, Gallo, Claudio, Bellante, Elvira, Bottura, Chiara, Zeringyte, Aurelija, Pasquali, Francesca, Boccacci, Simona, Latini, Giuseppe, Giannuzzi, Raffaella, Martinelli, Stefano, Brunelli, Alberto, Di Nunzio, Maria Lucia, Vendemmiati, Antonio, Carli, Giovanna, Bordigato, Michela Alfiero, Filippone, Marco, Meneghesso, Davide, Romeo, Nicola, Mammoliti, Palma, Mastretta, Emanuele, Barberis, Laura, Farina, Daniele, Gancia, Gianpaolo, Dalmazzo, Cristina, Napolitano, Marcello, Messina, Francesco, Villa Betania, Napoli, Magaldi, Rosario, Rinaldi, Matteo, Litta, Rosangela, Lago, Paola, Zanardo, Vincenzo, Chiandetti, Lino, Visentin, Stefano, Presta, Giuseppe, Cella, Davide, Poggiani, Carlo, Ferrari, Daniela, Parati, Sara, Lombardo, Francesco, Grigorio, Rosetta, Barera, Graziano, Bove, Maddalena, Poloniato, Antonella, Burgio, Giampiero, Sala, Elena, Barberi, Ignazio, Tiralongo, Venera, Arco, Alessandro, Mazzeo, Danila, Dani, Carlo, Pratesi, Simone, Mignatti, Valeria, Ancora, Gina, Faldella, Giacomo, Grandi, Sara, Locatelli, Chiara, Stronati, Mauro, Perotti, Gianfranco, Chirico, Gaetano, Migliori, Claudio, De Marini, Sergio, Forleo, Vincenzo, Paludetto, Roberto, Capasso, Letizia, Mansi, Giuseppina, Raimondi, Francesco, Bona, Gianni, Stucchi, Ilaria, Savastio, Silvia, Ferrero, Federica, Parola, Andrea, Padovani, Ezio Maria, Viviani, Elena, Pecoraro, Laura, Agostino, Rocco, Gizzi, Camilla, Massenzi, Luca, Messner, Hubert, Staffler, Alex, Salvia, Gennaro, Esposito, Luigi, Forziati, Vincenzo, Latorre, Giuseppe, Sandri, Fabrizio, Alati, Stefania, Demarca, Fabrizio, Lombardi, Oreste, Costabile, Carmine Deni, Scarpelli, Gianfranco, Cavalli, Claudio, Volante, Enrico, Moretti, Sabrina, Ganguzza, Olga, Spinella, Bartolomeo, Haass, Cristina, Scapillati, Eleonora, Consigli, Chiara, Gatta, Alberto, Quitadamo, Pasqua, Boldrini, Antonio, Vuerich, Marco, Sigali, Emilio, Fiorini, Patrizio, Petrucci, Letizia, Moroni, Marco, Meyer, Firenze, Bragetti, Patrizia, Casucci, Paola, Minelli, Liliana, Mezzetti, Daniele, Orfeo, Luigi, De Luca, Maria Gabriella, Laforgia, Nicola, Grassi, Alessandro, Dotta, Andrea, Savignoni, Ferdinando, Bagnoli, Franco, De Felice, Claudio, Badii, Silvia, Biasini, Augusto, Belluzzi, Antonio, Stella, Marcello, Romagnoli, Costantino, Zecca, Enrico, Barone, Giovanni, Colleselli, Paolo, Vecchiato, Luca, Nicolussi, Silvia, Giliberti, Paolo, Chello, Giovanni, Rojo, Silvana, De Vivo, Massimiliano, Giovanettoni, Chiara, Colnaghi, Clelia A., Manfredini, Valeria, Verucci, Elena, Placidi, Giulia, Belloni, Cesare, Carrera, Giuseppe, Zambetti, Chiara, Biban, Paolo, Serra, Alessandra, Sacco, Francesco, Vetrano, Gennaro, Furcolo, Giuseppe, Pasquariello, Brigida, Falco, Luigi, Ausanio, Gaetano, Bernardo, Italo, Capasso, Antonella, Marchesano, Giuseppe, Nosari, Norberto, Sarnelli, Paola, Ciraci, Giovanni, Merazzi, Daniele, Gazzolo, Diego, Temperini, Francesca, Sabatini, Miriam, Colivicchi, Micaela, Del Vecchio, Antonio, Tarantino, Marzia, Gargano, Giancarlo, Pedori, Simona, Bellettato, Massimo, Pesavento, Roberta, Cesaro, Alessandra, Scollo, Massimo, Mondello, Isabella, Pugliese, Aniello, Iervolino, Claudio, Corsello, Giovanni, Giuffré, Mario, Betta, Pasqua, Romeo, Mario Giuseppe, Saporito, Alessandro, Leone, Maria Grazia, Rodonò, Alessandro, Franceschi, Alessia, Risso, Francesco M., Carpentieri, Mauro, Vecchiano, Teresa, Cigliano, Maria Pia, Paolillo, Piermichele, Picone, Simonetta, Marra, Antonio, Rossetti, Gessica, Testa, Tiziana, Del Cuore, Fernando, Crescenzi, Francesco, Poloni, Gianna, Russo, Maria Chiara, Nigro, Francesco, Tina, Gabriella Lucia, Brindisino, Patrizia, Gurrado, Raffaele, Felice, Maurizio, Formica, Isabella, Gagliardi, L, Rusconi, F, Bellu, R, Zanini, R, Corsello, G, Giuffre, M, Italian Neonatal Network, Luigi Gagliardi, Franca Rusconi, Roberto Bellù, Rinaldo Zanini, the Italian Neonatal Network [.., Gina Ancora, Giacomo Faldella, Sara Grandi, Chiara Locatelli, ]., Gagliardi, Luigi, Rusconi, Franca, Bellù, Roberto, Zanini, Rinaldo, Mirri, Gianpaolo, Condò, Manuela, Turoli, Daniela, Vanzati, Mara, Mosca, Fabio, De Nisi, Giuseppe, Polacco, Paola, Villa, Elena, Barbarini, Mario, Fasolato, Valeria, Franco, Caterina, Contiero, Raffaella, Ellero, Serena, Cattarossi, Luigi, Abbiati, Laura, Borroni, Cesarina, Prandi, Giovanna, Fabris, Claudio, Vielmi, Francesca, Borgione, Silvia, Agosti, Massimo, Tandoi, Francesco, Guidali, Rosanna, De Curtis, Mario, Tozzi, Claudio, Lucchini, Renato, Battaglioli, Marina, Lista, Gian Luca, Introvini, Paola, Ferrari, Fabrizio, Gallo, Claudio, Bellante, Elvira, Bottura, Chiara, Zeringyte, Aurelija, Pasquali, Francesca, Boccacci, Simona, Latini, Giuseppe, Giannuzzi, Raffaella, Martinelli, Stefano, Brunelli, Alberto, Di Nunzio, Maria Lucia, Vendemmiati, Antonio, Carli, Giovanna, Bordigato, Michela Alfiero, Filippone, Marco, Meneghesso, Davide, Romeo, Nicola, Mammoliti, Palma, Mastretta, Emanuele, Barberis, Laura, Farina, Daniele, Gancia, Gianpaolo, Dalmazzo, Cristina, Napolitano, Marcello, Messina, Francesco, Villa Betania, Napoli, Magaldi, Rosario, Rinaldi, Matteo, Litta, Rosangela, Lago, Paola, Zanardo, Vincenzo, Chiandetti, Lino, Visentin, Stefano, Presta, Giuseppe, Cella, Davide, Poggiani, Carlo, Ferrari, Daniela, Parati, Sara, Lombardo, Francesco, Grigorio, Rosetta, Barera, Graziano, Bove, Maddalena, Poloniato, Antonella, Burgio, Giampiero, Sala, Elena, Barberi, Ignazio, Tiralongo, Venera, Arco, Alessandro, Mazzeo, Danila, Dani, Carlo, Pratesi, Simone, Mignatti, Valeria, Ancora, Gina, Faldella, Giacomo, Grandi, Sara, Locatelli, Chiara, Stronati, Mauro, Perotti, Gianfranco, Chirico, Gaetano, Migliori, Claudio, De Marini, Sergio, Forleo, Vincenzo, Paludetto, Roberto, Capasso, Letizia, Mansi, Giuseppina, Raimondi, Francesco, Bona, Gianni, Stucchi, Ilaria, Savastio, Silvia, Ferrero, Federica, Parola, Andrea, Padovani, Ezio Maria, Viviani, Elena, Pecoraro, Laura, Agostino, Rocco, Gizzi, Camilla, Massenzi, Luca, Messner, Hubert, Staffler, Alex, Salvia, Gennaro, Esposito, Luigi, Forziati, Vincenzo, Latorre, Giuseppe, Sandri, Fabrizio, Alati, Stefania, Demarca, Fabrizio, Lombardi, Oreste, Costabile, Carmine Deni, Scarpelli, Gianfranco, Cavalli, Claudio, Volante, Enrico, Moretti, Sabrina, Ganguzza, Olga, Spinella, Bartolomeo, Haass, Cristina, Scapillati, Eleonora, Consigli, Chiara, Gatta, Alberto, Quitadamo, Pasqua, Boldrini, Antonio, Vuerich, Marco, Sigali, Emilio, Fiorini, Patrizio, Petrucci, Letizia, Moroni, Marco, Meyer, Firenze, Bragetti, Patrizia, Casucci, Paola, Minelli, Liliana, Mezzetti, Daniele, Orfeo, Luigi, De Luca, Maria Gabriella, Laforgia, Nicola, Grassi, Alessandro, Dotta, Andrea, Savignoni, Ferdinando, Bagnoli, Franco, De Felice, Claudio, Badii, Silvia, Biasini, Augusto, Belluzzi, Antonio, Stella, Marcello, Romagnoli, Costantino, Zecca, Enrico, Barone, Giovanni, Colleselli, Paolo, Vecchiato, Luca, Nicolussi, Silvia, Giliberti, Paolo, Chello, Giovanni, Rojo, Silvana, De Vivo, Massimiliano, Giovanettoni, Chiara, Colnaghi, Clelia A., Manfredini, Valeria, Verucci, Elena, Placidi, Giulia, Belloni, Cesare, Carrera, Giuseppe, Zambetti, Chiara, Biban, Paolo, Serra, Alessandra, Sacco, Francesco, Vetrano, Gennaro, Furcolo, Giuseppe, Pasquariello, Brigida, Falco, Luigi, Ausanio, Gaetano, Bernardo, Italo, Capasso, Antonella, Marchesano, Giuseppe, Nosari, Norberto, Sarnelli, Paola, Ciraci, Giovanni, Merazzi, Daniele, Gazzolo, Diego, Temperini, Francesca, Sabatini, Miriam, Colivicchi, Micaela, Del Vecchio, Antonio, Tarantino, Marzia, Gargano, Giancarlo, Pedori, Simona, Bellettato, Massimo, Pesavento, Roberta, Cesaro, Alessandra, Scollo, Massimo, Mondello, Isabella, Pugliese, Aniello, Iervolino, Claudio, Corsello, Giovanni, Giuffré, Mario, Betta, Pasqua, Romeo, Mario Giuseppe, Saporito, Alessandro, Leone, Maria Grazia, Rodonò, Alessandro, Franceschi, Alessia, Risso, Francesco M., Carpentieri, Mauro, Vecchiano, Teresa, Cigliano, Maria Pia, Paolillo, Piermichele, Picone, Simonetta, Marra, Antonio, Rossetti, Gessica, Testa, Tiziana, Del Cuore, Fernando, Crescenzi, Francesco, Poloni, Gianna, Russo, Maria Chiara, Nigro, Francesco, Tina, Gabriella Lucia, Brindisino, Patrizia, Gurrado, Raffaele, Felice, Maurizio, and Formica, Isabella

Subjects
Male, Pediatrics, Logistic models, Mortality, Outcomes, Pregnancy complications, Preterm infants, Risks, Female, Gestational Age, Humans, Infant, Newborn, Infant, Premature, Diseases, Pregnancy, Pregnancy Outcome, Prospective Studies, Chorioamnionitis, Hypertension, Pregnancy-Induced, Pediatrics, Perinatology and Child Health, Medicine (all), Arts and Humanities (miscellaneous), Diseases, outcomes, Maternal hypertension, risk, Obstetrics, pregnancy complications, Gestational age, Retinopathy of prematurity, Perinatology and Child Health, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, Logistic models, Mortality, Outcomes, Pregnancy complications, Preterm infants, Risks, Necrotizing enterocolitis, Hypertension, outcome, Human, medicine.medical_specialty, Pregnancy-Induced, preterm infant, Pregnancy complication, medicine, preterm infants, Premature, logistic model, Chorioamnioniti, business.industry, Infant, Infant, Premature, Disease, Odds ratio, medicine.disease, Newborn, mortality, Prospective Studie, Bronchopulmonary dysplasia, business, logistic models, risks
Abstract

OBJECTIVES: We compared the relative effect of hypertensive disorders of pregnancy and chorioamnionitis on adverse neonatal outcomes in very preterm neonates, and studied whether gestational age (GA) modulates these effects. METHODS: A cohort of neonates 23 to 30 weeks' GA, born in 2008 to 2011 in 82 hospitals adhering to the Italian Neonatal Network, was analyzed. Infants born from mothers who had hypertensive disorders (N = 2096) were compared with those born after chorioamnionitis (N = 1510). Statistical analysis employed logistic models, adjusting for GA, hospital, and potential confounders. RESULTS: Overall mortality was higher after hypertension than after chorioamnionitis (odds ratio [OR], 1.39; 95% confidence interval [CI], 1.08–1.80), but this relationship changed across GA weeks; the OR for hypertension was highest at low GA, whereas from 28 weeks' GA onward, mortality was higher for chorioamnionitis. For other outcomes, the relative risks were constant across GA; infants born after hypertension had an increased risk for bronchopulmonary dysplasia (OR, 2.20; 95% CI, 1.68–2.88) and severe retinopathy of prematurity (OR, 1.48; 95% CI, 1.02–2.15), whereas there was a lower risk for early-onset sepsis (OR, 0.25; 95% CI, 0.19–0.34), severe intraventricular hemorrhage (OR, 0.65; 95% CI, 0.48–0.88), periventricular leukomalacia (OR, 0.70; 95% CI, 0.48–1.01), and surgical necrotizing enterocolitis or gastrointestinal perforation (OR, 0.47; 95% CI, 0.31–0.72). CONCLUSIONS: Mortality and other adverse outcomes in very preterm infants depend on antecedents of preterm birth. Hypertension and chorioamnionitis are associated with different patterns of outcomes; for mortality, the effect changes across GA weeks.

Published
2014

31. Neuroprem: the Neuro-developmental outcome of very low birth weight infants in an Italian region.

Author

Lugli, Licia, Pugliese, Marisa, Plessi, Carlotta, Berardi, Alberto, Guidotti, Isotta, Ancora, Gina, Grandi, Sara, Gargano, Giancarlo, Braibanti, Silvia, Sandri, Fabrizio, Soffritti, Silvia, Ballardini, Elisa, Arena, Vittoria, Stella, Marcello, Perrone, Serafina, Moretti, Sabrina, Rizzo, Vittoria, Ferrari, Fabrizio, Picciolini, Odoardo, and Bellù, Roberto

Subjects
LOW birth weight, CEREBRAL palsy, DEVELOPMENTAL disabilities, FUNCTIONAL assessment, LONGITUDINAL method, NEONATAL intensive care, RISK assessment, NEONATAL intensive care units, DESCRIPTIVE statistics, DISEASE risk factors
Abstract

Introduction: The survival of preterm babies has increased worldwide, but the risk of neuro-developmental disabilities remains high, which is of concern to both the public and professionals. The early identification of children at risk of neuro-developmental disabilities may increase access to intervention, potentially influencing the outcome. Aims: Neuroprem is an area-based prospective cohort study on the neuro-developmental outcome of very low birth weight (VLBW) infants that aims to define severe functional disability at 2 years of age. Methods: Surviving VLBW infants from an Italian network of 7 neonatal intensive care units (NICUs) were assessed for 24 months through the Griffiths Mental Developmental Scales (GMDS-R) or the Bayley Scales of Infant and Toddler Development (BSDI III) and neuro-functional evaluation according to the International Classification of Disability and Health (ICF-CY). The primary outcome measure was severe functional disability at 2 years of age, defined as cerebral palsy, a BSDI III cognitive composite score < 2 standard deviation (SD) or a GMDS-R global quotients score < 2 SD, bilateral blindness or deafness. Results: Among 211 surviving VLBW infants, 153 completed follow-up at 24 months (72.5%). Thirteen patients (8.5%) developed a severe functional disability, of whom 7 presented with cerebral palsy (overall rate of 4.5%). Patients with cerebral palsy were all classified with ICF-CY scores of 3 or 4. BSDI III composite scores and GMDS-R subscales were significantly correlated with ICF-CY scores (p < 0.01). Conclusion: Neuroprem represents an Italian network of NICUs aiming to work together to ensure preterm neuro-developmental assessment. This study updates information on VLBW outcomes in an Italian region, showing a rate of cerebral palsy and major developmental disabilities in line with or even lower than those of similar international studies. Therefore, Neuroprem provides encouraging data on VLBW neurological outcomes and supports the implementation of a preterm follow-up programme from a national network perspective. [ABSTRACT FROM AUTHOR]

Published
2020
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37. Neonatal respiratory distress syndrome: are risk factors the same in preterm and term infants?

Author

Condò, Valentina, Cipriani, Sonia, Colnaghi, Mariarosa, Bellù, Roberto, Zanini, Rinaldo, Bulfoni, Camilla, Parazzini, Fabio, and Mosca, Fabio

Subjects
RESPIRATORY distress syndrome, NEONATAL diseases, GESTATIONAL age, MULTIVARIATE analysis, PREGNANCY, DISEASE risk factors
Abstract

Objective: To analyze respiratory distress syndrome (RDS) incidence and risk factors at different gestational age. Methods:We considered data from 321 327 infants born in Lombardy, a Northern Italian Region. We computed multivariate analysis to identify risk factors for RDS by dividing infants in early- and moderate-preterm, late-preterm and term infants. Results: Low-birth weight is the main risk factor for RDS, with higher odds ratio in term births. The risk was higher in infants delivered by cesarean section and in male, for all gestational age. Pathological course of pregnancy resulted in increased risk only in late-preterm and term infants. Maternal age and multiple birth were not associated with increased risk in any group. Babies born at term after assisted conception were at higher risk of RDS. Conclusion: Our analysis suggests as some risk factors do not influence RDS incidence in the same way at different gestational age. [ABSTRACT FROM AUTHOR]

Published
2017
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38. La 'qualità della care' come protezione degli stati depressivi nelle madri di bambini nati pretermine. Risultati dello studio NEO-ACQUA

Author

DELLA VEDOVA, ANNA MARIA, CRISTINI, CARLO, Montirosso, Rosario, Bellù, Roberto, Calciolari, Guido, Cavallo, Maria Cristina, Del Prete, Alberto, Provenzi, Livio, Borgatti, Renato, Gruppo Di Studio Neo, Acqua, Borgatti, Renato (ORCID:0000-0001-8165-4994), DELLA VEDOVA, ANNA MARIA, CRISTINI, CARLO, Montirosso, Rosario, Bellù, Roberto, Calciolari, Guido, Cavallo, Maria Cristina, Del Prete, Alberto, Provenzi, Livio, Borgatti, Renato, Gruppo Di Studio Neo, Acqua, and Borgatti, Renato (ORCID:0000-0001-8165-4994)

Abstract

N/A

Published
2011

40. What we talk about when we talk about NICUs: infants' acuity and nurse staffing.

Author

Gagliardi, Luigi, Corchia, Carlo, Bellù, Roberto, Coscia, Alessandra, Zangrandi, Antonello, and Zanini, Rinaldo

Subjects
NEONATAL intensive care, PEDIATRIC intensive care, INTENSIVE care nursing, NEONATAL emergencies, HOSPITAL care of newborn infants, THERAPEUTICS
Abstract

Objective: Organizational features of neonatal intensive care influence the care of sick neonates. We estimated the acuity-adjusted nurse-to-patient ratio (NPR) in a national sample of Italian NICUs and factors influencing it.Methods: Twelve monthly cross-sectional surveys were prospectively carried out in 63 NICUs. Number and acuity of infants, and number of nurses were recorded. Infants' acuity was assessed by Rogowki's 2013 and British Association for Perinatal Medicine 2001 classifications.Results: We collected 702 reports regarding 11 082 infants. Non-intensive infants represented about 75% of NICU residents. Very preterm infants (<1501 g birth weight or <30 weeks gestation) represented 10.8% of admissions, but 44% of all infants surveyed. Average acuity-adjusted NPR was 0.31 (interquartile range 0.28-0.38); NPR depended on case-mix (proportion of intensive infants), size of the unit (larger units had a lower NPR) and was higher during morning shifts (+18%). Clustering on hospitals, reflecting shared components within each hospital, explained 47% of the variability of NPR.Conclusions: The majority of infants cared for in NICUs are not intensive. NPR is influenced by acuity of infants, size of units, shifts, but is largely due to other unobserved hospital-related organizational features. [ABSTRACT FROM AUTHOR]

Published
2016
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46. Does quality of developmental care in NICUs affect health-related quality of life in 5-y-old children born preterm?

Author

Montirosso, Rosario, Giusti, Lorenzo, Del Prete, Alberto, Zanini, Rinaldo, Bellù, Roberto, and Borgatti, Renato

Abstract

Background:Preterm birth and Neonatal Intensive Care Unit (NICU) stay are early adverse experiences, which may affect health-related quality of life (HRQoL) even in the absence of prematurity-related morbidities. The aim of this multicenter longitudinal study was to examine the relation between quality levels of NICU Developmental Care (DC) and HRQoL at 60 mo in children who were born preterm.Methods:HRQoL of 102 very preterm (VPT) children from 20 NICUs and 110 full-term controls was assessed using TNO-AZL Preschool Children’s Quality of Life Questionnaire (TAPQOL). In VPT children, we compared HRQoL by splitting NICUs into units with high- and low-quality of DC according to the following two factors: (i) the infant centered care (ICC), and (ii) the infant pain management (IPM).Results:Compared to VPT children from NICUs with high-quality of ICC, VPT children from NICUs with low-quality in ICC scored lower in HRQoL component which resulted from the aggregation of lively, positive emotionality, social and motor functioning. No differences were found between VPT children from high-quality ICC NICUs and full-term children and for the IPM index.Conclusion:Findings suggest that higher quality of DC in NICU related to ICC might mitigate long-term negative quality of life outcomes.

Published
2016
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