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1,012 results on '"Bell, Derek"'

1. Albumin Versus Balanced Crystalloid for the Early Resuscitation of Sepsis: An Open Parallel-Group Randomized Feasibility Trial. The ABC-Sepsis Trial

Author

Gray, Alasdair J., Oatey, Katherine, Grahamslaw, Julia, Irvine, Sîan, Cafferkey, John, Kennel, Titouan, Norrie, John, Walsh, Tim, Lone, Nazir, Horner, Daniel, Appelboam, Andy, Hall, Peter, Skipworth, Richard J. E., Bell, Derek, Rooney, Kevin, Shankar-Hari, Manu, Corfield, Alasdair R., Newcombe, Virginia, Chapman, Robert, Hutton, Corinne, Perkins, Gavin, Gordon, Anthony, Keating, Liza, Pallmann, Philip, Armstrong, Ruth, Pollock, Roz, Wackett, Tony, Chapman, Robert, Hutton, Corrine, Kale, Jane, Kale, Neville, Anderson, Rory, Birrell, David, Black, Polly, Blackstock, Caroline, Carter, Jonathan, Clark, Donna, Davidson, Craig, Davie, Carlyn, Rollo, Nicola Di, Ferguson, Andrew, Fethers, Nicholas, Freeman, Nicola, Gibson, Louise, Grant, Alison, Harris, Marie-Clare, James, Ed, Letham, Katy, Lynch, Stephen, McCurrach, Fiona, McKenzie, Suzi, McLaughlin, Connor, Miell, Anna, Moncur, Lyle, O’Brien, Rachel, Pickering, Gillian, Reed, Matt, Rezai, Roozbeh, Robinson, Sara, Skinner, Janet, Walker, Craig, Williams, Alison, Wilson, Emma-Beth, Di Rollo, Nicola, Carruthers, Jennifer, Cheyne, Claire, McGeough, Angela, Lidstone-Scott, Rebecca, Lynch, Stephen, Abel, Lynn, Bongale, Santosh, Currie, Susie, Kane, Donna, Keen, Rachel, Orlikowska, Izabella, Rodden, Natalie, Tait, Jennifer, Thomson, Nicola, Walker, Lauren, Smith, Kate, Brown, Ammani, Cathcart, Susanne, Maguire, Donogh, O’Mailley, Patrick, Rimmer, Dominic, Ward, Catherine, Baxter, Nicola, Denny, Fraser, Doran, Kayleigh, Dunlop, Lisa, Dunn, Jessica, Finnen, Lisa, Green, Darren, Hughes, Emma, Lowe, David, McArthur, Courtney, McLaren, Barbara, McLeish, Kirsty, McMunigal, Linda, McParland, Chris, O’Shaughnessy, Ornagh, Wilson, Mark, Armes, Roland, Brown, Craig, Cooper, Jamie, Connor, David, Collier-Wakefield, Otto, Coutts, Mandi, Cruickshank, Mairi, Ebtehadj, Bianca, Ganley, Pauline, Hiscox, John, Hartman, Catharina, Kane, Leia, Kastora, Stavroula, Lamb, Sarah, McCarthy, Sinead, Mulholland, Conal, Nadim, Imran, Noble, Jennifer, Patton, Gareth, Savage, David, Spowage-Delaney, Benjamin, Doonan, Reece, Lee, Stephanie, Strange, Joshua, Barham, Ffion, Bosanko, Clare, Bullough, Richard, Danglosi, Joan, Freeman, Elaine, Jackson, Luci-Adele, James, Robert, Jose, Louise, Lowe, Fionna, Lowther, Ashleigh, McCarthy, Ian, McConnell, David, Parry, Richard, Shirreff, Henry, Smith, Jason, Squire, Rosalyn, Battishill, Wayne, Boggaram, Girish, Chilcott, Gemma, Gagg, James, Machin, Emma, Shovelton, Charmaine, Purnell, Rebecca, Crosthwaite-Eyre, Richard, Page, George, Pitt, Andrew, Riou, Peter, Sykes, Daisy, Worth, Cassie, Zitter, Lily, Baron, Tanya, Baskaran, Dineshbabu, Beer, Sally, Bhargav, Akshay, Blamey, Helen, Brown, Charlotte, Clare-Gray, Benjamin, Davies, Matthew, Dawson, Neil, Dineen, Karen, Edgar, Iain, Erasu, Vishakha, Faisal, Muhammad, Georgiou, Dominique, Gibson, Alice, Ghataoura, Rashpal, Glover, Samuel, Gordon, Olivia, Ilyas, Sadaf, Jeffs, Aimee, Knott, Henry, Kundoor, Sneha, Martinez, Jose, McCallum, Andrew, Novak, Alex, Panduro, Tine, Pattanshetty, Ravi, Paul, Immanuel, Magallano, Rufino Roger, Razdan, Pamposh, Sambo, Tinelly, Shah, Sumaiyah, Shaikh, Ayisha, Smith, Simon, Thraves, Hannah, Tickle, Charlotte, Ang, Justin, Boyle, Adrian, Hardwick, Susie, Meynell, Kerry, Miller, Samuel, Charsley, Julia, Jolly, Sarah, Mahony, Faye, Moseley-Rodgers, Jade, Sivayoham, Narani, Sheerin, Thomas, Seel, Claire, Abdalla, Mohamed, Cameron, Gregor, Harnett, James, Ramos, Daryl, Perez, Fabiola Sevilla, White, Rachel, Abdullah, Wajiha, Ballard, Suzanna, Barnes, Katie, Clegg, Rebecca, Cousins, Elisha, Cumiskey, Simon, Elwir, Bashar, Ferriman, Alexander, Fletcher, Alison, Griffiths, Charlotte, Guiling, Paolyn, Johnson, Graham, Loach, Benjamin, Matthews, Alison, May-Moulden, Lucy, Norman, Rebecca, Seelly, Helen, Smith, Richard, Tabner, Andrew, Tilbury, Nicholas, Ward, Thomas, Wright, Lianne, Wroblewski, Heather, and Zawadzka, Marcelina

Published
2024
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3. Patient and Public Views on Electronic Health Records and Their Uses in the United Kingdom: Cross-Sectional Survey

Author

Luchenski, Serena A, Reed, Julie E, Marston, Cicely, Papoutsi, Chrysanthi, Majeed, Azeem, and Bell, Derek

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundThe development and implementation of electronic health records (EHRs) remains an international challenge. Better understanding of patient and public attitudes and the factors that influence overall levels of support toward EHRs is needed to inform policy. ObjectiveTo explore patient and public attitudes toward integrated EHRs used simultaneously for health care provision, planning and policy, and health research. MethodsCross-sectional questionnaire survey administered to patients and members of the public who were recruited from a stratified cluster random sample of 8 outpatient clinics of a major teaching hospital and 8 general practices in London (United Kingdom). Results5331 patients and members of the public responded to the survey, with 2857 providing complete data for the analysis presented here. There were moderately high levels of support for integrated EHRs used simultaneously for health care provision, planning and policy, and health research (1785/2857, 62.47%), while 27.93% (798/2857) of participants reported being undecided about whether or not they would support EHR use. There were higher levels of support for specific uses of EHRs. Most participants were in favor of EHRs for personal health care provision (2563/2857, 89.71%), with 66.75% (1907/2857) stating that they would prefer their complete, rather than limited, medical history to be included. Of those “undecided” about integrated EHRs, 87.2% (696/798) were nevertheless in favor of sharing their full (373/798, 46.7%) or limited (323/798, 40.5%) records for health provision purposes. There were similar high levels of support for use of EHRs in health services policy and planning (2274/2857, 79.59%) and research (2325/2857, 81.38%), although 59.75% (1707/2857) and 67.10% (1917/2857) of respondents respectively would prefer their personal identifiers to be removed. Multivariable analysis showed levels of overall support for EHRs decreasing with age. Respondents self-identifying as Black British were more likely to report being undecided or unsupportive of national EHRs. Frequent health services users were more likely to report being supportive than undecided. ConclusionsDespite previous difficulties with National Health Service (NHS) technology projects, patients and the public generally support the development of integrated EHRs for health care provision, planning and policy, and health research. This support, however, varies between social groups and is not unqualified; relevant safeguards must be in place and patients should be guided in their decision-making process, including increased awareness about the benefits of EHRs for secondary uses.

Published
2013
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7. Maximizing wound coverage in full-thickness skin defects: A randomized-controlled trial of autologous skin cell suspension and widely meshed autograft versus standard autografting

Author

Henry, Sharon, Mapula, Steven, Grevious, Mark, Foster, Kevin N., Phelan, Herbert, Shupp, Jeffrey, Chan, Rodney, Harrington, David, Mashruwala, Neil, Brown, David A., Mir, Haaris, Singer, George, Cordova, Alfredo, Rae, Lisa, Chin, Theresa, Castanon, Lourdes, Bell, Derek, Hughes, William, and Molnar, Joseph A.

Published
2024
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18. Effect of implementing a heart failure admission care bundle on hospital readmission and mortality rates: interrupted time series study

Author

Woodcock, Thomas, primary, Matthew, Dionne, additional, Palladino, Raffaele, additional, Nakubulwa, Mable, additional, Winn, Trish, additional, Bethell, Hugh, additional, Hiles, Stephen, additional, Moggan, Susan, additional, Dowell, Jackie, additional, Sullivan, Paul, additional, Bell, Derek, additional, and Cowie, Martin R, additional

Published
2023
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24. Albumin versus Balanced Crystalloid for the early resuscitation of sepsis: a randomised feasibility trial. The ABC-Sepsis Trial.

Author

Gray, Alasdair, primary, Oatey, Katherine, additional, Grahamslaw, Julia, additional, Irvine, Sîan, additional, Cafferkey, John, additional, Kennel, Titouan, additional, Norrie, John, additional, Walsh, Tim, additional, Lone, Nazir, additional, Horner, Daniel, additional, Appelbaum, Andy, additional, Hall, Peter, additional, Skipworth, Richard, additional, Bell, Derek, additional, Rooney, Kevin, additional, Shankar-Hari, Manu, additional, and Corfield, Alasdair, additional

Published
2023
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26. Accessing Science in the Primary School: Meeting the Challenges of Children with Learning Difficulties.

Author

Bell, Derek

Abstract

The principle of education for all is one which few people, if any, would argue against but putting it into practice is one of the biggest challenges facing everyone involved in education. Internationally, nationally and locally attempts are being made to develop and put in place policies and structures which will lead to an inclusivity of education which meets the needs of all students. Children with learning difficulties are only one group for whom access to many aspects of education have been denied. Despite the obstacles, however, there has been much progress in opening up opportunities for them. However, unless teachers are able to help these children access the curriculum, the policies and structures that have been put in place are of little value. This paper examines some of the challenges facing teachers of children with learning difficulties in primary schools as they try to make science accessible to their pupils. Traditionally, such children have been given little in the way of scientific problems to explore but, it is argued, that science can make a significant contribution to the education of children with learning difficulties. The value and effectiveness of the contribution will be realized only if teachers can recognize the barriers to learning that these children face and have the skills to help their pupils overcome these difficulties. Examples of teacher-pupil interactions are used to illustrate the issues raised and some implications for mainstream teaching suggested. (Author)

Published
1999

36. Effect of implementing a heart failure admission care bundle on hospital readmission and mortality rates: interrupted time series study.

Author

Woodcock, Thomas, Matthew, Dionne, Palladino, Raffaele, Nakubulwa, Mable, Winn, Trish, Bethell, Hugh, Hiles, Stephen, Moggan, Susan, Dowell, Jackie, Sullivan, Paul, Bell, Derek, and Cowie, Martin R.

Subjects
EVALUATION of human services programs, HOSPITALS, THERAPEUTICS, ECHOCARDIOGRAPHY, CONFIDENCE intervals, RESEARCH methodology, PATIENTS, PATIENT readmissions, REGRESSION analysis, HOSPITAL admission & discharge, HOSPITAL mortality, QUALITY assurance, TIME series analysis, DESCRIPTIVE statistics, RESEARCH funding, PATIENT care, PEPTIDE hormones, LOGISTIC regression analysis, DATA analysis software, ACUTE diseases, HEART failure, POISSON distribution
Abstract

This study aimed to evaluate the impact of developing and implementing a care bundle intervention to improve care for patients with acute heart failure admitted to a large London hospital. The intervention comprised three elements, targeted within 24 hours of admission: Nterminal pro-B-type natriuretic peptide (NT-proBNP) test, transthoracic Doppler two-dimensional echocardiography and specialist review by cardiology team. The SHIFTEvidence approach to quality improvement was used. During implementation, July 2015--July 2017, 1169 patients received the intervention. An interrupted time series design was used to evaluate impact on patient outcomes, including 15 618 admissions for 8951 patients. Mixed-effects multiple Poisson and log-linear regression models were fitted for count and continuous outcomes, respectively. Effect sizes are slope change ratios preintervention and post-intervention. The intervention was associated with reductions in emergency readmissions between 7 and 90 days (0.98, 95% CI 0.97 to 1.00), although not readmissions between 0 and 7 days post-discharge. Improvements were seen in in-hospital mortality (0.96, 95% CI 0.95 to 0.98), and there was no change in trend for hospital length of stay. Care process changes were also evaluated. Compliance with NT-proBNP testing was already high in 2014/2015 (162 of 163, 99.4%) and decreased slightly, with increased numbers audited, to 2016/2017 (1082 of 1101, 98.2%). Over this period, rates of echocardiography (84.7-98.9%) and specialist input (51.6-90.4%) improved. Care quality and outcomes can be improved for patients with acute heart failure using a care bundle approach. A systematic approach to quality improvement, and robust evaluation design, can be beneficial in supporting successful improvement and learning. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Principles and practical criteria for effective participatory environmental planning and decision-making.

Author

Carrick, Jayne, Bell, Derek, Fitzsimmons, Clare, Gray, Tim, and Stewart, Gavin

Subjects
*DELIBERATIVE democracy, *ENVIRONMENTAL justice, *DECISION making, *PROCEDURAL justice, *FAIR value, ENVIRONMENTAL protection planning
Abstract

Participation is increasingly used to legitimize and improve environmental decision making. However, in practice participants often find the process empty and frustrating. This has adverse consequences for environmental planning and consenting processes, where participants become disillusioned, and negative feelings develop into active opposition, causing delays, spiraling costs, and conflict. This paper addresses the gap between participatory ideals and unsatisfactory environmental decision-making in practice. We take a fresh look at how participatory ideals can be implemented and propose a new framework based on translating participatory ideals into practice. We identified commitments and values for fair and achievable participatory environmental decision-making from science and technology studies (STS), procedural environmental justice, and deliberative democracy. These were synthesized and organized into a set of principles (inclusivity, process-orientation, empowerment, and reflection) and then translated into "practical" criteria. The result is a new framework that links participatory ideals to practice. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Leaving the hospital on time: hospital bed utilization and reasons for discharge delay in the Netherlands

Author

van den Ende, Eva, primary, Schouten, Bo, additional, Pladet, Lara, additional, Merten, Hanneke, additional, van Galen, Louise, additional, Marinova, Milka, additional, Schinkel, Michiel, additional, Boerman, Anneroos W, additional, Nannan Panday, Rishi, additional, Rustemeijer, Cees, additional, Dulaimy, Muhammad, additional, Bell, Derek, additional, and Nanayakkara, Prabath Wb, additional

Published
2023
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43. Maximizing Wound Coverage in Full-Thickness Skin Defects: A Randomized-Controlled Trial of Autologous Skin Cell Suspension and Widely Meshed Autograft Versus Standard Autografting

Author

Henry, Sharon, Mapula, Steven, Grevious, Mark, Foster, Kevin N., Phelan, Herbert, Shupp, Jeffrey, Chan, Rodney, Harrington, David, Mashruwala, Neil, Brown, David A., Mir, Haaris, Singer, George, Cordova, Alfredo, Rae, Lisa, Chin, Theresa, Castanon, Lourdes, Bell, Derek, Hughes, William, Molnar, Joseph A., Henry, Sharon, Mapula, Steven, Grevious, Mark, Foster, Kevin N., Phelan, Herbert, Shupp, Jeffrey, Chan, Rodney, Harrington, David, Mashruwala, Neil, Brown, David A., Mir, Haaris, Singer, George, Cordova, Alfredo, Rae, Lisa, Chin, Theresa, Castanon, Lourdes, Bell, Derek, Hughes, William, and Molnar, Joseph A.

Abstract

BACKGROUND: Traumatic insults, infection, and surgical procedures can leave skin defects that are not amenable to primary closure. Split-thickness skin grafting (STSG) is frequently used to achieve closure of these wounds. Although effective, STSG can be associated with donor site morbidity, compounding the burden of illness in patients undergoing soft tissue reconstruction procedures. With an expansion ratio of 1:80, autologous skin cell suspension (ASCS) has been demonstrated to significantly decrease donor skin requirements compared with traditional STSG in burn injuries. We hypothesized that the clinical performance of ASCS would be similar for soft tissue reconstruction of nonburn wounds. METHODS: A multicenter, within-patient, evaluator-blinded, randomized-controlled trial was conducted of 65 patients with acute, nonthermal, full-thickness skin defects requiring autografting. For each patient, two treatment areas were randomly assigned to concurrently receive a predefined standard-of-care meshed STSG (control) or ASCS + more widely meshed STSG (ASCS+STSG). Coprimary endpoints were noninferiority of ASCS+STSG for complete treatment area closure by Week 8, and superiority for relative reduction in donor skin area. RESULTS: At 8 weeks, complete closure was observed for 58% of control areas compared with 65% of ASCS+STSG areas (p = 0.005), establishing noninferiority of ASCS+STSG. On average, 27.4% less donor skin was required with ASCS+ STSG, establishing superiority over control (p < 0.001). Clinical healing (≥95% reepithelialization) was achieved in 87% and 85% of Control and ASCS+STSG areas, respectively, at 8 weeks. The treatment approaches had similar long-term scarring outcomes and safety profiles, with no unanticipated events and no serious ASCS device-related events. CONCLUSION: ASCS+STSG represents a clinically effective and safe solution to reduce the amount of skin required to achieve definitive closure of full-thickness defects without compromising he

Published
2023

44. Domain-Specific Inhibitory Control Training to Improve Children’s Learning of Counterintuitive Concepts in Mathematics and Science

Author

Wilkinson, Hannah R., Smid, Claire, Morris, Su, Farran, Emily K., Dumontheil, Iroise, Mayer, Sveta, Tolmie, Andrew, Bell, Derek, Porayska-Pomsta, Kaśka, Holmes, Wayne, Mareschal, Denis, and Thomas, Michael S. C.

Abstract

Evidence from cognitive neuroscience suggests that learning counterintuitive concepts in mathematics and science requires inhibitory control (IC). This prevents interference from misleading perceptual cues and naïve theories children have built from their experiences of the world. Here, we (1) investigate associations between IC, counterintuitive reasoning, and academic achievement and (2) evaluate a classroom-based computerised intervention, called Stop & Think, designed to embed IC training within the learning domain (i.e. mathematics and science content from the school curricula). Cross-sectional analyses of data from 627 children in Years 3 and 5 (7- to 10-year-olds) demonstrated that IC, measured on a Stroop-like task, was associated with counterintuitive reasoning and mathematics and science achievement. A subsample (n= 456) participated either in Stop & Think as a whole-class activity (teacher-led, STT) or using individual computers (pupil-led, STP), or had teaching as usual (TAU). For Year 3 children (but not Year 5), Stop & Think led to better counterintuitive reasoning (i.e. near transfer) in STT (p< .001, ηp2= .067) and STP (p< .01, ηp2= .041) compared to TAU. Achievement data was not available for Year 3 STP or Year 5 STT. For Year 3, STT led to better science achievement (i.e. far transfer) compared to TAU (p< .05, ηp2= .077). There was no transfer to the Stroop-like measure of IC. Overall, these findings support the idea that IC may contribute to counterintuitive reasoning and mathematics and science achievement. Further, we provide preliminary evidence of a domain-specific IC intervention with transferable benefits to academic achievement for Year 3 children.

Published
2024
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