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15 results on '"Belfiori, Barbara"'

5. An Italian Case of Disseminated Histoplasmosis Associated with HIV

Author

Papalini, Chiara, Belfiori, Barbara, Martino, Giovanni, Papili, Rita, Pitzurra, Lucia, Ascani, Stefano, and Pasticci, Maria Bruna

Subjects
Article Subject
Abstract

Histoplasma capsulatum is a dimorphic fungus, endemic in the Americas, Africa (var. duboisii), India, and Southeast Asia. H. capsulatum infection is rarely diagnosed in Italy, while in Latin America, progressive disseminated histoplasmosis (PDH) is one of the most frequent AIDS-defining illnesses and causes of AIDS-related deaths. We report a case of PDH and new HIV infection diagnosis in a Cuban patient, who has been living in Italy for the past 10 years. Bone marrow aspirate and peripheral blood smear microscopy suggested H. capsulatum infection. The diagnosis was confirmed with the culture method identifying its thermal dimorphism. Liposomal amphotericin B was administered alone for 10 days and then for another 2 days, accompanied with voriconazole; the former was stopped for probable side effects (persistent fever and worsening thrombocytopenia), and voriconazole was continued to complete 4 weeks. PDH maintenance treatment consisted of itraconazole for one year. Antiretroviral therapy (ART) was started on the third week of antifungal treatment. At the 3-year follow-up, the patient is adherent on ART, the virus was suppressed, and she has an optimal immune recovery. This case highlights the need to suspect histoplasmosis in the differential diagnosis of opportunistic infections in immunocompromised persons, native to or who have traveled to endemic countries.

Published
2019
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8. In vivo platelet activation and platelet hyperreactivity in abacavir-treated HIV-infected patients

Author

Belfiori, Barbara, primary, Petito, Eleonora, primary, Guglielmini, Giuseppe, primary, Malincarne, Lisa, primary, Mezzasoma, AnnaMaria, primary, Sebastiano, Manuela, primary, Conti, Valentina, primary, Giannini, Silvia, primary, Bonora, Stefano, primary, Baldelli, Franco, primary, Falcinelli, Emanuela, additional, Francisci, Daniela, additional, and Gresele, Paolo, additional

Published
2013
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14. [HIV infection in older patients: an emerging problem].

Author

Francisci D, Masini G, Belfiori B, and Baldelli F

Subjects
Aged, HIV Infections epidemiology, Humans, Middle Aged, HIV Infections drug therapy
Abstract

Over the last years the proportion of old individuals infected with HIV is increasing. Epidemiological data show that HIV-infected patients is ageing in parallel with the use of potent treatment and that the number of older patients who are newly diagnosed is increasing. Older people have a higher prevalence of sexual HIV transmission and the infection tend to be diagnosed at an advanced stage. Management of HIV infection in older patients is particularly complex for presence of co-morbidities that may be worse the antiretroviral treatment (ART) associated toxicity. Information campaigns targeting older patients and their doctors are needed to ensure timely diagnosis of HIV infection and ART.

Published
2008

15. Prevalence, incidence and clinical outcome of hepatitis B virus and hepatitis C virus hepatitis in patients undergoing allogeneic hematopoietic stem cell transplantation between 2001 and 2004.

Author

Francisci D, Aversa F, Coricelli V, Carotti A, Canovari B, Falcinelli F, Belfiori B, Aloisi T, Baldelli F, Martelli MF, and Stagni G

Subjects
Adolescent, Adult, Aged, Child, Hematopoietic Stem Cell Transplantation methods, Histocompatibility, Humans, Incidence, Lymphocyte Depletion, Middle Aged, Prevalence, Prospective Studies, Transplantation, Homologous, Treatment Outcome, Hematopoietic Stem Cell Transplantation adverse effects, Hepatitis B etiology, Hepatitis C etiology
Abstract

The prevalence, incidence and clinical course of viral hepatitis were prospectively determined in consecutive recipients of T-cell depleted hematopoieic stem cell transplants (49 mismatched, 60 matched, mean age 38 years; range 11-65). The prevalence of hepatitis B virus (HBV) was 15.6% and that of hepatitis C virus was 3.7% (HCV). HBV reactivated in one patient. Another developed ex novo acute hepatitis B which progressed to chronic hepatitis. There were no new cases of hepatitis C or worsening of pre-transplant HCV infections. HBV and HBC did not affect the outcome of T-cell depleted hematopoieic stem cell transplantation. Surveillance is important given the risk of HCV and HBV infection and/or reactivation and the efficacy of the new anti-hepatitis drugs.

Published
2006

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