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Your search keyword '"Belangero, W. D."' showing total 12 results
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12 results on '"Belangero, W. D."'

1. Online Studies on Variation in Orthopedic Surgery: Computed Tomography in MPEG4 Versus DICOM Format

Author

Mellema, Jos J., Mallee, Wouter H., Guitton, Thierry G., van Dijk, C. Niek, Ring, David, Doornberg, Job N., Babis, G. C., Jeray, K. J., Prayson, M. J., Pesantez, R., Acacio, R., Verbeek, D. O., Melvanki, P., Kreis, B. E., Mehta, S., Meylaerts, S., Wojtek, S., Yeap, E. J., Haapasalo, H., Kristan, A., Coles, C., Marsh, J. L., Mormino, M., Menon, M., Tyllianakis, M., Schandelmaier, P., Jenkinson, R. J., Neuhaus, V., Shahriar, C. M. H., Belangero, W. D., Kannan, S. G., Leonidovich, G. M., Davenport, J. H., Kabir, K., Althausen, P. L., Weil, Y., Toom, A., Sa da Costa, D., Lijoi, F., Koukoulias, N. E., Manidakis, N., Van den Bogaert, M., Patczai, B., Grauls, A., Kurup, H., van den Bekerom, M. P., Lansdaal, J. R., Vale, M., Ousema, P., Barquet, A., Cross, B. J., Broekhuyse, H., Haverkamp, D., Merchant, M., Harvey, E., Pemovska, E. Stojkovska, Frihagen, F., Seibert, F. J., Garnavos, C., van der Heide, H., Villamizar, H. A., Harris, I., Borris, L. C., Brink, O., Brink, P. R. G., Choudhari, P., Swiontkowski, M., Mittlmeier, T., Tosounidis, T., van Rensen, I., Martinelli, N., Park, D. H., Lasanianos, N., Vide, J., Engvall, A., Zura, R. D., Jubel, A., Kawaguchi, A., Goost, H., Bishop, J., Mica, L., Pirpiris, M., van Helden, S. H., Bouaicha, S., Schepers, T., Havliček, T., Giordano, V., and Science of Variation Group & Traumaplatform Study Collaborative

Published
2017
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5. Tribological properties of polyvinyl alcohol hydrogels as artificial articular cartilage

Author

Sardinha, V. M., Belangero, W. D., Bavaresco, V. P., Gomes, J. R., Câmara, Fabricio Vitor, Ferreira, Leandro J., and Universidade do Minho

Subjects
integumentary system, Engenharia e Tecnologia::Engenharia dos Materiais, PVA, Biotribologia, Hydrogels, Articular cartilage
Abstract

An exhaustive scientific investigation has been performed on polymeric hydrogels as potential materials to be used in cartilage tissue repair or replacement. Polyvinyl alcohol (PVA) possesses excellent properties as biocompatibility, low coefficient of friction, low interfacial tension and high permeability to fluids, emerging as an eligible material to be studied for biomedical applications. The main goal of this study was the tribological characterization of PVA hydrogels in lubricated sliding with distilled water and phosphate buffered saline solution (PBS). The influence of hydrogels mechanical properties and operating conditions were considered. Tribological tests were performed on a pin-on-plate tribometer with a linear reciprocating geometry using the PVA/stainless steel 316L and PVA/bovine articular cartilage pairs. Experiments were performed at 37 °C with a constant reciprocating sliding frequency of 1 Hz and applied load of 1 MPa, 2 MPa and 3.5 MPa. For each experiment the friction coefficient was determined and the dominating wear mechanisms analysed by scanning electron microscopy and EDS. PVA showed an excellent performance as possible material for the repair of articular cartilage due to the high level of surface preservation and the very low friction coefficient presented when PBS was used as fluid lubricant. The performed tribological study revealed the high potentiality of PVA hydrogels to be used as artificial articular cartilage., (undefined)

Published
2012

8. International orthopaedic Multicentre study (INORMUS) in fracture care: Protocol for a large prospective observational study INORMUS investigators

Author

Bhandari, M., PJ Devereaux, Ivers, R. Q., Miclau, T., Moroz, P., Thabane, L., Sprague, S., Mckay, P., Li, C. S., Jagnoor, J., Slobogean, G., Boniface, R., Browner, B., La Huerta, F., Pollak, A., Petrisor, B., Sancheti, P., Schemitsch, E., Zhou, J., Guyatt, G., Devereaux, P. J., Mundi, R., O Hara, N., Heels-Ansdell, D., Buckingham, L., Simunovic, N., Norton, R., Zhang, J., Tian, M., Yadav, L., Caldwell, A., Liu, Y., Wang, Q., Li, J., Zhang, Z., Zhang, W., Tian, S., Jia, Z., Guo, T., Ma, Y., Wu, G., Ma, X., Ma, J., Jia, H., Hu, S., Wang, Y., Sun, M., Qin, Y., Wang, J., Zhou, S., Qi, B., Wu, B., Zhi, C., Xing, B., Zhu, Y., Zhang, X., Yang, J., Dai, W., Lu, D., He, S., Cai, X., Liu, G., Rui, G., Hu, B., Chen, H., Hu, Y., Wang, T., Shyam, A., Borate, M., Gawande, N., Jadhav, N., Patil, S. D., Karkamakar, S., Patil, S., Ranaware, A., Tamboli, S., Gandhalikar, M., Tupe, R., Choudhary, V., Patil, P. V., Shetty, V., Shetty, N., Hegde, C., Shrivastava, S., Singh, P., Dhillon, M. S., Dhatt, S. S., Agrawal, G., Mittal, R., Sharma, V., John, B., Mahajan, A., Afzal, P. A., Prakash, J. S., Cherian, V. M., Jepegnanam, T. S., Titus, V. T. K., Nithyananth, M., Boopalan, P. R., Varghese, V. D., George, V. M., Rajagopalan, N., Nair, N., Amaravathy, R., Santhanagopal, S., Pilar, A., Chhabra, H. S., D Souza, A., Chawla, P., Raina, D., Vaksha, V., Subramanian, P., Moabelo, R. S., Segbefia, M., Baidoo, P. K., Ocloo, C. A., Baddoo, D. T., Ativor, V., Yeboah, D. K., Konadu, P., Kumah-Ametepey, R., Awariyah, D., Quartey, R., Saani, O., Quansah, R. E., Trafton, P., Anyitey-Kokor, D., Leat, M., Sobotey, J., Opuni, G., Agbenorwu, F., Gis, B. B. W. G., Ayana, B., Otsyeno, F. M. T., Jani, P., Mutiso, V. M., Atinga, J. E. O., Kilonzo, P. K., Muoki, J., Mbogori, M., Wambugu, J. W., Torutt, D., Odok, C., Kipkemoi, E., Otsyeno, D., Desmondnzioka, J. W., Owende, D., Lucinde, R., Kariuki, B., Kinyua, D., Kamau, M., Mwancha, M., Murgor, M., Nyabuti, M., Njoki, R., Lutomia, M., Nancy, N., Ndeleva, B. M., Johnson, M., Kimani, M., Gichui, K., Mara, M., Mwangi, G. C., Maina, A. M., Wamae, D., Mwangi, C., Kingori, I., Watson, P., Kiptoo, E. M., Temiloluwa, O. O., Ikechukwu, A. A., Bamidele, O. I., Akanbi, O. O., Olugbenga, I. O., Firth, G., Biscardi, A. G., Machuene, A. P., Moolman, J., Miller, B., Ramokgopa, M., Deventer, S., Pikor, T., Bhaga, R., Marealle, P., Wanini, A., Elisha, M., Zumbulu, D., Boniface, R. L., Temu, R., Mutanda, T., Ntuulo, J., Lubega, F., Tracy, G. T., Zaitun, K., Godfrey, P. B., Mandizvidza, V., Gova, M. F., Sabur, M. A., Qavi, M. I., Khundkar, T., Wangdi, K., Wangmo, N., Dorji, S., Baker, S., Thapa, J., Lodrel, K., Dorji, U., Saadat, S., Zafarghandi, M., Golbakhsh, M., Byanjankar, S., Joshi, R. R., Dwivedi, R., Sharma, J. R., Qadir, R. I., Bukhari, S. I., Baz, K. A., Wahid, I., Quang, L. N., Cuong Pham, V., Chinh, N. D., Amanquez, C., Vincenti, S. I., Bobarin, A. P., Sanchez, D. S., Elias, N., Ribeiro, J. E. G., Belangero, W. D., Mariolani, J. R. L., Livani, B., Lugnani, A., Rossi, F., Katayama, A., Kfuri, M., Fogagnolo, F., Baldy, F., Moraes, V. Y., Kojima, K. E., Dos Santos Silva, J., Demange, M. K., Andrade E Silva, F. B., Dan Silva, A. C. G., Quintero, J. E., Contreras, F., Merchan, G., Beauvoir, G., Mercado, E., Medina, F., Aguilar, G., Rubio-Avila, J., Ochoa, H. C., Cano, H. C., González, A. V., Gutierrez, N. I. G., Orozco, C. F., Jesús Martínez Ruíz, J., Martinez, D. A., Garuz, M., Altieri, J. S., Cutipa, I. J. S., Lurita, C. L., Manrique, D. T., Fernandez, J. H., Barquet, A., Rienzi, D., Elguezabal, I. A. E., Rizzo, E. A., Hovsepian, J. M., and Rodriguez, V.

10. Biomechanical and histological evaluation of hydrogel implants in articular cartilage.

Author

Malmonge SM, Zavaglia CA, and Belangero WD

Subjects
Animals, Biomechanical Phenomena, Cartilage, Articular pathology, Cartilage, Articular surgery, Male, Rats, Rats, Wistar, Biocompatible Materials therapeutic use, Cartilage, Articular physiology, Femur, Hydrogel, Polyethylene Glycol Dimethacrylate therapeutic use, Materials Testing, Prosthesis Implantation
Abstract

We evaluated the mechanical behavior of the repaired surfaces of defective articular cartilage in the intercondylar region of the rat femur after a hydrogel graft implant. The results were compared to those for the adjacent normal articular cartilage and for control surfaces where the defects remained empty. Hydrogel synthesized by blending poly(2-hydroxyethyl methacrylate) and poly(methyl methacrylate-co-acrylic acid) was implanted in male Wistar rats. The animals were divided into five groups with postoperative follow-up periods of 3, 5, 8, 12 and 16 weeks. Indentation tests were performed on the neoformed surfaces in the knee joint (with or without a hydrogel implant) and on adjacent articular cartilage in order to assess the mechanical properties of the newly formed surface. Kruskal-Wallis analysis indicated that the mechanical behavior of the neoformed surfaces was significantly different from that of normal cartilage. Histological analysis of the repaired defects showed that the hydrogel implant filled the defect with no signs of inflammation as it was well anchored to the surrounding tissues, resulting in a newly formed articular surface. In the case of empty control defects, osseous tissue grew inside the defects and fibrous tissue formed on the articular surface of the defects. The repaired surface of the hydrogel implant was more compliant than normal articular cartilage throughout the 16 weeks following the operation, whereas the fibrous tissue that formed postoperatively over the empty defect was stiffer than normal articular cartilage after 5 weeks. This stiffness started to decrease 16 weeks after the operation, probably due to tissue degeneration. Thus, from the biomechanical and histological point of view, the hydrogel implant improved the articular surface repair.

Published
2000
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11. Inherited risk factors for thrombophilia among children with Legg-Calvé-Perthes disease.

Author

Arruda VR, Belangero WD, Ozelo MC, Oliveira GB, Pagnano RG, Volpon JB, and Annichino-Bizzacchi JM

Subjects
Adolescent, Child, Child, Preschool, DNA Mutational Analysis, Factor V genetics, Female, Heterozygote, Humans, Legg-Calve-Perthes Disease etiology, Male, Methylenetetrahydrofolate Reductase (NADPH2), Oxidoreductases Acting on CH-NH Group Donors deficiency, Oxidoreductases Acting on CH-NH Group Donors genetics, Risk Factors, Thrombophilia complications, Legg-Calve-Perthes Disease genetics, Thrombophilia genetics
Abstract

An inherited tendency to hypercoagulability has been suggested as a cause of vascular thrombosis resulting in Legg-Calvé-Perthes disease (LCPD). Here we carried out an investigation of the most common inherited risk factors for hypercoagulability including the mutation in the factor V gene (factor V Leiden), the transition 20.210G-->A in the prothrombin gene, and also the homozygosity for the 677C-->T transition in the methylenetetrahydrofolate reductase gene (MTHFR). The investigation was carried out among 61 Brazilian children with LCPD, who were compared with 296 individuals from the general population. The prevalence of the factor V Leiden mutation was higher in LCPD patients than in the controls (4.9 vs. 0.7%; p = 0.03). However, no patient had the prothrombin gene variant, and no difference was found between patients and controls when homozygosity for MTHFR-T (3.2 vs. 2.6%: p = 0.64) was determined. These data suggest that in our population, the heterozygosity for factor V Leiden was the only inherited risk factor associated with the development of LCPD.

Published
1999

12. Inflammatory reaction of rat striated muscle to particles of carbon fiber reinforced carbon.

Author

Belangero WD, Köberle G, and Hadler WA

Subjects
Animals, Female, Inflammation etiology, Inflammation pathology, Rats, Rats, Wistar, Time Factors, Biocompatible Materials, Carbon, Foreign-Body Reaction pathology, Muscles pathology, Prostheses and Implants
Abstract

1. Carbon fiber reinforced carbon (CFRC) was implanted in rats as particles measuring 30 microns or 11 microns, denoted as CFRC-A and CFRC-B, respectively. Titanium (Ti) and vitreous carbon (VC) were used as controls. Ti was used with the same particle size as CFRC (Ti-A or Ti-B). The VC particles measured 11 microns. All materials were separately sterilized on ethylene oxide before use. 2. One hundred and ten female Wistar rats, weighing 180 to 220 g, were divided into six groups of 4 to 5 animals each, according the time of the observation (1, 2, 4, 8, 16 and 52 weeks). 3. Under aseptic conditions, one 3-0 curette full of CFRC-A or CFRC-B was implanted into the right triceps surae muscle in each animal and the same quantity of Ti-A (paired with CFRC-A) or Ti-B or VC (paired with CFRC-B) was implanted into the left muscle. 4. Histological analysis did not show necrosis of muscular tissue nor exudative reaction during the acute phase. 5. During the chronic phase the particles induced a chronic inflammatory infiltration containing fibroblasts, macrophages and giant cells. VC and CFRC-B induced the lowest inflammatory infiltration and CFRC-A induced the highest one. 6. We suggest that the longer carbon fiber fragments contained in CFRC-A may be responsible for this more intensive reaction, which may restrict the medical use of the preparation.

Published
1993

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