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479 results on '"Beijk, Marcel A."'

1. Deferral of routine percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation: Rationale and design of the PRO-TAVI trial

Author

Aarts, Hugo M., Hemelrijk, Kimberley I., Broeze, Gijs M., van Ginkel, Dirk Jan, Versteeg, Geert A.A., Overduin, Daniel C., Tijssen, Jan G., Beijk, Marcel A.M., Baan, Jan, Vis, Marije M., Lemkes, Jorrit S., de Winter, Robbert J., Dickinson, Michael G., Kraaijeveld, Adriaan O., Mokhles, Mostafa M., Dessing, Thomas C., Grundeken, Maik J., Claessen, Bimmer E.P.M., Tonino, Pim A.L., Schotborgh, Carl E., Meuwissen, Martijn, van Houwelingen, Gert K., Wykrzykowska, Joanna J., Amoroso, Giovanni, Vossenberg, Tessel N., Vriesendorp, Pieter A., van Royen, Niels, ten Berg, Jurriën M., Delewi, Ronak, and Voskuil, Michiel

Published
2025
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3. Impact of sex on the assessment of the microvascular resistance reserve

Author

Boerhout, Coen K.M., Vink, C.E.M., Lee, Joo Myung, de Waard, Guus A., Mejia-Renteria, Hernan, Lee, Seung Hun, Jung, Ji-Hyun, Hoshino, Masahiro, Echavarria-Pinto, Mauro, Meuwissen, Martijn, Matsuo, Hitoshi, Madera-Cambero, Maribel, Eftekhari, Ashkan, Effat, Mohamed A., Murai, Tadashi, Marques, Koen, Doh, Joon-Hyung, Christiansen, Evald H., Banerjee, Rupak, Nam, Chang-Wook, Niccoli, Giampaolo, Nakayama, Masafumi, Tanaka, Nobuhiro, Shin, Eun-Seok, Appelman, Yolande, Beijk, Marcel A.M., van Royen, Niels, Chamuleau, Steven A.J., Knaapen, Paul, Escaned, Javier, Kakuta, Tsunekazu, Koo, Bon Kwon, Piek, Jan J., and van de Hoef, Tim P.

Published
2024
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7. Prognostic Implications of Individual and Combinations of Resting and Hyperemic Coronary Pressure and Flow Parameters

Author

Yang, Seokhun, Hwang, Doyeon, Lee, Joo Myung, Lee, Seung Hun, Boerhout, Coen K.M., Woudstra, Janneke, Vink, Caitlin E.M., de Waard, Guus A., Jung, Ji Hyun, Renteria, Hernan Mejia, Hoshino, Masahiro, Pinto, Mauro Echavarria, Meuwissen, Martijn, Matsuo, Hitoshi, Cambero, Maribel Madera, Eftekhari, Ashkan, Effat, Mohamed A., Murai, Tadashi, Marques, Koen, Appelman, Yolande, Doh, Joon Hyung, Christiansen, Evald H., Banerjee, Rupak, Kim, Hyun Kuk, Nam, Chang Wook, Niccoli, Giampaolo, Nakayama, Masafumi, Tanaka, Nobuhiro, Shin, Eun Seok, Beijk, Marcel A.M., Chamuleau, Steven A.J., van Royen, Niels, Knaapen, Paul, Kakuta, Tsunekazu, Escaned, Javier, Piek, Jan J., van de Hoef, Tim P., and Koo, Bon-Kwon

Published
2023
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8. Sex differences in prevalence and outcomes of the different endotypes of chronic coronary syndrome in symptomatic patients undergoing invasive coronary angiography: Insights from the global ILIAS invasive coronary physiology registry

Author

Vink, Caitlin E.M., Woudstra, Janneke, Lee, Joo Myung, Boerhout, Coen K.M., Cook, Christopher M., Hoshino, Masahiro, Mejia-Renteria, Hernan, Lee, Seung Hun, Jung, Ji-Hyun, Echavarria-Pinto, Mauro, Meuwissen, Martijn, Matsuo, Hitoshi, Madera-Cambero, Maribel, Eftekhari, Ashkan, Effat, Mohamed A., Murai, Tadashi, Marques, Koen, Beijk, Marcel A.M., Doh, Joon-Hyung, Piek, Jan J., van de Hoef, Tim P., Christiansen, Evald Høj, Banerjee, Rupak, Nam, Chang-Wook, Niccoli, Giampaolo, Nakayama, Masafumi, Tanaka, Nobuhiro, Shin, Eun-Seok, van Royen, Niels, Chamuleau, Steven A.J., Knaapen, Paul, Escaned, Javier, Kakuta, Tsunekazu, Koo, Bon-Kwon, Appelman, Yolande, and de Waard, Guus A.

Published
2023
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9. Abnormal physiological findings after FFR-based revascularisation deferral are associated with worse prognosis in women

Author

Hoshino, Masahiro, van de Hoef, Tim P., Lee, Joo Myung, Hamaya, Rikuta, Kanaji, Yoshihisa, Boerhout, Coen K. M., de Waard, Guus A., Jung, Ji-Hyun, Lee, Seung Hun, Mejia-Renteria, Hernan, Echavarria-Pinto, Mauro, Meuwissen, Martijn, Matsuo, Hitoshi, Madera-Cambero, Maribel, Eftekhari, Ashkan, Effat, Mohamed A., Marques, Koen, Doh, Joon-Hyung, Christiansen, Evald H., Banerjee, Rupak, Nam, Chang-Wook, Niccoli, Giampaolo, Murai, Tadashi, Nakayama, Masafumi, Tanaka, Nobuhiro, Shin, Eun-Seok, Sasano, Tetsuo, Appelman, Yolande, Beijk, Marcel, Knaapen, Paul, van Royen, Niels, Escaned, Javier, Koo, Bon Kwon, Piek, Jan J., and Kakuta, Tsunekazu

Published
2023
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13. Angina Severity and Symptom Improvement Are Associated With Diagnostic Acetylcholine Provocation Dose in Vasospastic Angina.

Author

Crooijmans, C., Jansen, Tijn P. J., Meeder, Joan G., Paradies, Valeria, de Vos, Annemiek M. J., Woudstra, Pier, Vossenberg, Tessel N. E., van de Hoef, Tim P., Vos, Nicola S., Bijvank, Els G. M. Olde, van den Oord, Stijn C. H., Winkler, Patty, Meuwissen, Martijn, Widdershoven, Jos W. M. G., Arkenbout, E. Karin, Stoel, Martin G., Appelman, Yolande, Beijk, Marcel A. M., Cetinyurek-Yavuz, Aysun, and den Ruijter, Hester M.

Published
2025
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17. 1-Year Clinical Outcomes of All-Comer Patients Treated With the Dual-Therapy COMBO Stent: Primary Results of the COMBO Collaboration

Author

Colombo, Antonio, Mehran, Roxana, Ong, Tiong Kiam, Lee, Michael, Iniguez, Andres, Rowland, Stephen, Ghodsi, Newsha, Marx, Steven, DiStefano, Douglas, Weinberger, Jesse, Wong, Shing Chiu, Darrow, Bruce, Kaufman, David, Milstein, Mark, Chandrasekhar, Jaya, Baber, Usman, Aquino, Melissa, Sartori, Samantha, Snyder, Clayton, Franklin-Bond, Theresa, Cha, Jin Young, Vandertie, Lynn, Whittaker, Emma, Allen, Kate, Vogel, Birgit, Farhan, Serdar, Sorrentino, Sabato, Ge, Zhen, Carlier, Marc, Pourbaix, Suzanne, Borisov, Borislav, Atzev, Borislav, Vasilev, Dobrin, Christou, Christos, Pešl, Ladislav, Coufal, Zdeněk, Kala, Petr, Jeřábek, Petr, Hájek, Petr, Schee, Alexander, Ondrejcak, Roman, Rozsíval, Vladimír, Matějka, Jan, Mates, Martin, Khashaba, Ahmed, Warda, Hazem, Margus, Sulev, Yan, Bryan, Lam, Cheuk Sum, Chung, Tak Sun, Tam, Li Wah, Chan, Alan Ka Chun, Tsui, Ping Tim, Tsui, Kin Lam, Santoso, Teguh, Munawar, Muhammad, Syukri, Muhammad, Sinaga, Dasdo Antonius, Lupi, Alessandro, Briguori, Carlo, Maskon, Oteh, Kazim, Sazzli, Lee, Chuey Yan, Liew, Houng Bang, Ali, Rosli Mohammad, Singh, Ramesh, Den Heijer, Peter, Wojcik, Jaroslaw, Vukčević, Vladan, Hudec, Martin, Farkaš, Anton, Juhás, Stanislav, Jankajová, Monika, Dragula, Milan, Cuellas Ramon, Carlos, Tejedor, Paula, Ruiz-Poveda, Fernando Lozano, Bosco, Alfonso Torres, Boughzela, Essia, Slim, Medhi, Haouala, Habib, Lahidheb, Dhaker, Boujnah, Mohamed Rachid, Goode, Grahame K., Dhamrait, Sukhbir, Gerber, Robert, Clifford, Piers, Kinnaird, Timothy, Varnagy, Gabriel, Aguiar R., Pedro J., Huynh, Thuong Van, Menown, Ian B, den Heijer, Peter, van't Hof, Arnoud WJ, Erglis, Andrejs, Suryapranata, Harry, Arkenbout, Karin E, Iñiguez, Andrés, Muller, Philippe, Tijssen, Jan, de Winter, Robbert J, Beijk, Marcel A, Koch, Karel, Woudstra, Pier, Kalkman, Deborah N, de Winter, Robbert J., Kalkman, Deborah N., Aquino, Melissa B., Beijk, Marcel A., Tijssen, Jan G., Koch, Karel T., and Dangas, George D.

Published
2018
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18. Relationship between peripheral and intracoronary blood flow in patients with angina and nonobstructive coronary arteries.

Author

Woudstra, Janneke, Mourmans, Sanne G. J., Vink, Caitlin E. M., Marques, Koen M. J., Jong, Elize A. M. de, Haddad, Rahma Y. R., Hoef, Tim P. van de, Chamuleau, Steven A. J., Damman, Peter, Beijk, Marcel A. M., Empel, Vanessa P. M. van, Serné, Erik H., Appelman, Yolande, Eringa, Etto C., and consortium, on behalf of the IMPRESS

Subjects
VASCULAR smooth muscle, SPECKLE interference, CORONARY vasospasm, SODIUM nitroferricyanide, ENDOTHELIUM diseases
Abstract

Coronary vasomotor dysfunction, an important underlying cause of angina and nonobstructive coronary arteries (ANOCA), encompassing coronary vasospasm, coronary endothelial dysfunction, and/or coronary microvascular dysfunction, is clinically assessed by invasive coronary function testing (ICFT). As ICFT imposes a high burden on patients and carries risks, developing noninvasive alternatives is important. We evaluated whether coronary vasomotor dysfunction is a component of systemic microvascular endothelial and smooth muscle dysfunction and can be detected using laser speckle contrast analysis (LASCA). Forty-three consecutive patients with ANOCA underwent ICFT, with intracoronary acetylcholine, adenosine, and flow measurements, to assess coronary vasomotor dysfunction. Cutaneous microvascular function was assessed using LASCA in the forearm, combined with vasodilators acetylcholine, sodium nitroprusside, and insulin and using EndoPAT, by measuring the reactive hyperemia index (RHI). Of the 43 included patients with ANOCA (79% women, 59 ± 9 yr old), 38 patients had coronary vasomotor dysfunction, including 28 with coronary vasospasm, 26 with coronary endothelial dysfunction, and 18 with coronary microvascular dysfunction, with overlapping endotypes. Patients with and without coronary vasomotor dysfunction had similar peripheral flow responses to acetylcholine, insulin, and RHI. In contrast, coronary vasomotor dysfunction was associated with lower peripheral flow responses to sodium nitroprusside (P < 0.001). An absolute flow response to sodium nitroprusside of 83.95 APU resulted in 86.1% sensitivity and 80.0% specificity for coronary vasomotor dysfunction (area under the ROC curve, 0.883; P = 0.006). In conclusion, this study provides evidence of systemic vascular smooth muscle dysfunction in patients with ANOCA with coronary vasomotor dysfunction and the diagnostic value of peripheral microvascular function testing as a noninvasive tool for detecting coronary vasomotor dysfunction. NEW & NOTEWORTHY: This study provides proof of concept that assessment of the peripheral vasculature, particularly vascular smooth muscle cells measured using the LASCA technology holds potential as a noninvasive tool for detecting coronary vasomotor dysfunction. This finding highlights the potential of the LASCA technology in, for example, medication studies for coronary vasomotor dysfunction, especially when investigating whether medication improves vascular function, as repeated peripheral measurements are less invasive than invasive coronary function testing, the current gold standard. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Persistence of residual shunt at 6 and 12 months after transoesophageal echocardiography-guided percutaneous closure of a patent foramen ovale for cryptogenic stroke.

Author

Witte, Lars S., el Bouziani, Abdelhak, Beijk, Marcel A. M., Robbers-Visser, Danielle, Coutinho, Jonathan M., Tijssen, Jan G. P., Straver, Bart, Bouma, Berto J., and de Winter, Robbert J.

Subjects
TRANSIENT ischemic attack, PATENT foramen ovale, ATRIAL septum, RIGHT heart atrium, STROKE, VENTRICULAR septal defects, ATRIAL flutter
Published
2024
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20. 1-Year Outcomes with COMBO Stents in Small-Vessel Coronary Disease: Subgroup Analysis From the COMBO Collaboration

Author

Chandrasekhar, Jaya, Zeebregts, Doreen, Kalkman, Deborah N., Sartori, Samantha, Roumeliotis, Anastasios, Aquino, Melissa B., de Wilde, Puk, de Winter, Vera C., Baber, Usman, Woudstra, Pier, Beijk, Marcel A., Hájek, Petr, Atzev, Borislav, Hudec, Martin, Ong, Tiong Kiam, Mates, Martin, Borisov, Borislav, Warda, Hazem M., den Heijer, Peter, Wojcik, Jaroslaw, Iniguez, Andres, Lee, Michael, Tijssen, Jan G., Koch, Karel T., Dangas, George D., Colombo, Antonio, Mehran, Roxana, and de Winter, Robbert J.

Published
2020
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22. 1-Year Clinical Outcomes of All Comers Treated With 2 Bioresorbable Polymer-Coated Sirolimus-Eluting Stents: Propensity Score–Matched Comparison of the COMBO and Ultrathin-Strut Orsiro Stents

Author

von Birgelen, Clemens, Kok, Marlies M., van der Heijden, Liefke C., Danse, Peter W., Schotborgh, Carl E., Scholte, Martijn, Joe Gin, Melvin Tjon, Somi, Samer, van Houwelingen, K Gert, Stoel, Martin G., de Man, Frits H.A.F., Louwerenburg, J. (Hans) W., Hartmann, Marc, Zocca, Paolo, Linssen, Gerard C.M., van der Palen, Job, Doggen, Carine J.M., Löwik, Marije M., Chandrasekhar, Jaya, Kalkman, Deborah N., Aquino, Melissa B., Woudstra, Pier, Beijk, Marcel A., Kerkmeijer, Laura S., Sartori, Samantha, Baber, Usman, Tijssen, Jan G., Koch, Karel T., Dangas, George D., Colombo, Antonio, Pocock, Stuart, Mehran, Roxana, and de Winter, Robbert J.

Published
2020
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24. A paradox in sex-specific clinical outcomes after bioresorbable scaffold implantation: 2-year results from the AIDA trial

Author

Kerkmeijer, Laura S.M., Tijssen, Ruben Y.G., Hofma, Sjoerd H., Pinxterhuis, Tineke H., Kraak, Robin P., Kalkman, Deborah N., van der Schaaf, Rene J., Arkenbout, E. Karin, Weevers, Auke P.J.D., Beijk, Marcel A., Baan, Jan, Jr, Vis, M. Marije, Koch, Karel T., Tijssen, Jan G.P., Piek, Jan J., Henriques, Jose P.S., de Winter, Robbert J., and Wykrzykowska, Joanna J.

Published
2020
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26. Comparison of the Diagnostic Yield of Intracoronary Acetylcholine Infusion and Acetylcholine Bolus Injection Protocols During Invasive Coronary Function Testing

Author

Cardiologie, Experimentele Afd. Cardiologie 1, Team Medisch, Circulatory Health, Woudstra, Janneke, Feenstra, Rutger G.T., Vink, Caitlin E.M., Marques, Koen M.J., Boerhout, Coen K.M., de Jong, Elize A.M., de Waard, Guus A., van de Hoef, Tim P., Chamuleau, Steven A.J., Eringa, Etto C., Piek, Jan J., Appelman, Yolande, Beijk, Marcel A.M., Cardiologie, Experimentele Afd. Cardiologie 1, Team Medisch, Circulatory Health, Woudstra, Janneke, Feenstra, Rutger G.T., Vink, Caitlin E.M., Marques, Koen M.J., Boerhout, Coen K.M., de Jong, Elize A.M., de Waard, Guus A., van de Hoef, Tim P., Chamuleau, Steven A.J., Eringa, Etto C., Piek, Jan J., Appelman, Yolande, and Beijk, Marcel A.M.

Published
2024

27. Impact of sex on the assessment of the microvascular resistance reserve

Author

Cardiologie, Team Medisch, Circulatory Health, Boerhout, Coen K.M., Vink, C. E.M., Lee, Joo Myung, de Waard, Guus A., Mejia-Renteria, Hernan, Lee, Seung Hun, Jung, Ji Hyun, Hoshino, Masahiro, Echavarria-Pinto, Mauro, Meuwissen, Martijn, Matsuo, Hitoshi, Madera-Cambero, Maribel, Eftekhari, Ashkan, Effat, Mohamed A., Murai, Tadashi, Marques, Koen, Doh, Joon Hyung, Christiansen, Evald H., Banerjee, Rupak, Nam, Chang Wook, Niccoli, Giampaolo, Nakayama, Masafumi, Tanaka, Nobuhiro, Shin, Eun Seok, Appelman, Yolande, Beijk, Marcel A.M., van Royen, Niels, Chamuleau, Steven A.J., Knaapen, Paul, Escaned, Javier, Kakuta, Tsunekazu, Koo, Bon Kwon, Piek, Jan J., van de Hoef, Tim P., Cardiologie, Team Medisch, Circulatory Health, Boerhout, Coen K.M., Vink, C. E.M., Lee, Joo Myung, de Waard, Guus A., Mejia-Renteria, Hernan, Lee, Seung Hun, Jung, Ji Hyun, Hoshino, Masahiro, Echavarria-Pinto, Mauro, Meuwissen, Martijn, Matsuo, Hitoshi, Madera-Cambero, Maribel, Eftekhari, Ashkan, Effat, Mohamed A., Murai, Tadashi, Marques, Koen, Doh, Joon Hyung, Christiansen, Evald H., Banerjee, Rupak, Nam, Chang Wook, Niccoli, Giampaolo, Nakayama, Masafumi, Tanaka, Nobuhiro, Shin, Eun Seok, Appelman, Yolande, Beijk, Marcel A.M., van Royen, Niels, Chamuleau, Steven A.J., Knaapen, Paul, Escaned, Javier, Kakuta, Tsunekazu, Koo, Bon Kwon, Piek, Jan J., and van de Hoef, Tim P.

Published
2024

28. Impact of coronary hyperemia on collateral flow correction of coronary microvascular resistance indices

Author

Team Medisch, Circulatory Health, Boerhout, Coen K M, Veelen, Anna van, Feenstra, Rutger G T, de Jong, Elize A M, Namba, Hanae F, Beijk, Marcel A M, Henriques, Jose P, Piek, Jan J, van de Hoef, Tim P, Team Medisch, Circulatory Health, Boerhout, Coen K M, Veelen, Anna van, Feenstra, Rutger G T, de Jong, Elize A M, Namba, Hanae F, Beijk, Marcel A M, Henriques, Jose P, Piek, Jan J, and van de Hoef, Tim P

Published
2024

29. Correction: van Veelen et al. First-in-Human Drug-Eluting Balloon Treatment of Vulnerable Lipid-Rich Plaques: Rationale and Design of the DEBuT-LRP Study. J. Clin. Med. 2023, 12, 5807

Author

van Veelen, Anna, primary, Küçük, I. Tarik, additional, Fuentes, Federico H., additional, Kahsay, Yirga, additional, Garcia-Garcia, Hector M., additional, Delewi, Ronak, additional, Beijk, Marcel A. M., additional, den Hartog, Alexander W., additional, Grundeken, Maik J., additional, Vis, M. Marije, additional, Henriques, José P. S., additional, and Claessen, Bimmer E. P. M., additional

Published
2024
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30. Percutaneous patent foramen ovale closure for hypoxaemia at the age of 73: a case report showing immediate benefit.

Author

Witte, Lars S, Straver, Bart, Bouma, Berto J, Winter, Robbert J de, and Beijk, Marcel A M

Subjects
PATENT foramen ovale, OXYGEN therapy, OXYGEN saturation, DISEASE complications, VENTRICULAR septal defects
Abstract

Background Approximately 25% of the general population has a patent foramen ovale (PFO) that remains asymptomatic in the vast majority. Right-to-left shunt (RLS)-mediated hypoxaemia is a rare associated condition of PFO. Case summary This report describes a case of percutaneous PFO closure for hypoxaemia in a 73-year-old patient showing immediate clinical benefit. She experienced progressive dyspnoea on exertion requiring oxygen therapy. SaO2 was 87% at rest without oxygen therapy, which increased to 98% after percutaneous PFO closure. Discussion Most PFOs remain clinically insignificant but RLS-mediated hypoxaemia is a rare phenomenon that can occur even at advanced age. Percutaneous PFO closure is a safe and effective therapy option that provides immediate improvement of hypoxaemia. [ABSTRACT FROM AUTHOR]

Published
2024
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31. Do electrocardiographic changes induced during intracoronary vasospasm provocation testing reflect those during spontaneous angina episodes in patients with vasospastic angina?: a case series.

Author

Feenstra, Rutger G T, Timmerman, Lotte S, Piek, Jan J, and Beijk, Marcel A M

Subjects
CORONARY vasospasm, ANGINA pectoris, SPASMS, CORONARY arteries, SYMPTOMS, ELECTROCARDIOGRAPHY
Abstract

Background According to the Coronary Vasomotor Disorders International Study (COVADIS) group, the ECG criteria supporting the diagnosis of vasospastic angina (VSA) in spontaneous episodes or induced during intracoronary spasm testing are similar. However, it remains elusive whether acetylcholine-induced ECG changes during epicardial spasms reflect ECG changes that occur during the height of a spontaneous episode. Case summary We present four patients diagnosed with VSA during intracoronary spasm testing, of whom the ECG characteristics during spasm testing and a spontaneous angina episode are described. All patients have >90% coronary epicardial vasoconstriction in one or more vessels during acetylcholine provocation. ECGs at the height of a spontaneous episode and during acetylcholine-induced coronary spasm are found to be different in three out of four patients. Discussion In patients with VSA, the ECG at the height of a spontaneous episode and during acetylcholine-induced coronary artery spasm may differ substantially. In patients with symptoms suspicious of VSA, every effort should be undertaken to obtain ECGs during the height of a spontaneous episode of angina pectoris and there should be a low threshold to perform intracoronary function testing. [ABSTRACT FROM AUTHOR]

Published
2024
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32. Lipoprotein(a) in interventional cardiology: identifying patients at highest risk of recurrent cardiovascular events through early recognition – a case based review.

Author

Renkens, Mick P. L., Coerkamp, Casper F., Witte, Lars S., Sivanesan, Shabiga, Nurmohamed, Nick S., Westerterp, Marit, Serruys, Patrick, Onuma, Yoshinobu, Grundeken, Maik J., Kalkman, Deborah N., Beijk, Marcel, Vis, Marije M., Henriques, José P. S., Delewi, Ronak, Stroes, Erik, Wykrzykowska, Joanna J., de Winter, Robbert J., and Claessen, Bimmer E. P. M.

Subjects
CORONARY artery disease, DISEASE risk factors, RISK assessment, SECONDARY prevention, DRUG therapy
Abstract

Introduction: Lipoprotein(a) [Lp(a)] is linked to higher risks of atherosclerotic cardiovascular disease (ASCVD). Current guideline recommendations are quite liberal on measuring Lp(a) (Class IIa, Level C), and may lead to underuse among (interventional) cardiologists. Areas covered: This case-based narrative review outlines four clinical cases of patients with elevated Lp(a) to illustrate its pathophysiological impact on coronary artery disease (CAD). The expert consensus statements from the American Heart Association (AHA) and European Atherosclerosis Society (EAS) served as the basis of this review. More recent publications, from 2023 to 2024, were accessed through the MEDLINE online library. Expert opinion: We highlighted the importance of routine Lp(a) measurement in identifying patients at high risk for atherosclerosis, necessitating potent risk mitigation. Measuring Lp(a) helps clinicians identify which patients are at highest residual risk, who require potent pharmacological treatment and special attention during catheter interventions. As noninvasive and advanced intravascular imaging modalities evolve, future catheterization laboratories will integrate advanced imaging, diagnostics, and treatment, facilitating tailored patient care. Knowing Lp(a) levels is crucial in this context. While Lp(a)-lowering drugs are currently investigated in clinical trials, it is of paramount importance to know Lp(a) levels and strive toward aggressive management of other modifiable risk factors in patients with elevated Lp(a) and established symptomatic CAD being diagnosed or treated in catheterization laboratories. [ABSTRACT FROM AUTHOR]

Published
2024
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34. The relationship of pre-procedural Dmax based sizing to lesion level outcomes in Absorb BVS and Xience EES treated patients in the AIDA trial

Author

Tijssen, Ruben Y. G., Kerkmeijer, Laura S. M., Katagiri, Yuki, Kraak, Robin P., Takahashi, Kuniaki, Kogame, Norihiro, Chichareon, Ply, Modolo, Rodrigo, Asano, Taku, Nassif, Martina, Kalkman, Deborah N., Sotomi, Yohei, Collet, Carlos, Hofma, Sjoerd H., van der Schaaf, Rene J., Arkenbout, E. Karin, Weevers, Auke P. J. D., Beijk, Marcel A. M., Piek, Jan J., Tijssen, Jan G. P., Henriques, Jose P., de Winter, Robbert J., Onuma, Yoshinobu, Serruys, Patrick W., and Wykrzykowska, Joanna J.

Published
2019
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35. Single antiplatelet therapy directly after percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome patients

Author

van der Sangen, Niels M. R., Claessen, Bimmer E. P. M., Küçük, I. Tarik, den Hartog, Alexander W., Baan, Jan, Beijk, Marcel A.M., Delewi, Ronak, van de Hoef, Tim P., Knaapen, Paul, Lemkes, Jorrit S., Marques, Koen M., Nap, Alexander, Verouden, Niels J. W., Marije Vis, M., de Winter, Robbert J., Kikkert, Wouter J., Appelman, Yolande, Henriques, Jose P. S., Cardiology, ACS - Atherosclerosis & ischemic syndromes, ACS - Microcirculation, Graduate School, ACS - Pulmonary hypertension & thrombosis, APH - Aging & Later Life, and ACS - Amsterdam Cardiovascular Sciences

Subjects
Cardiology and Cardiovascular Medicine
Abstract

BACKGROUND: Early P2Y12 inhibitor monotherapy has emerged as a promising alternative to 12 months of dual antiplatelet therapy following percutaneous coronary intervention (PCI). AIMS: In this single-arm pilot study, we evaluated the feasibility and safety of ticagrelor or prasugrel monotherapy directly following PCI in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). METHODS: Patients received a loading dose of ticagrelor or prasugrel before undergoing platelet function testing and subsequent PCI using new-generation drug-eluting stents. The stent result was adjudicated with optical coherence tomography in the first 35 patients. Ticagrelor or prasugrel monotherapy was continued for 12 months. The primary ischaemic endpoint was the composite of all-cause mortality, myocardial infarction, definite or probable stent thrombosis or stroke within 6 months. The primary bleeding endpoint was Bleeding Academic Research Consortium type 2, 3 or 5 bleeding within 6 months. RESULTS: From March 2021 to March 2022, 125 patients were enrolled, of whom 75 ultimately met all in- and exclusion criteria (mean age 64.5 years, 29.3% women). Overall, 70 out of 75 (93.3%) patients were treated with ticagrelor or prasugrel monotherapy directly following PCI. The primary ischaemic endpoint occurred in 3 (4.0%) patients within 6 months. No cases of stent thrombosis or spontaneous myocardial infarction occurred. The primary bleeding endpoint occurred in 7 (9.3%) patients within 6 months. CONCLUSIONS: This study provides first-in-human evidence that P2Y12 inhibitor monotherapy directly following PCI for NSTE-ACS is feasible, without any overt safety concerns, and highlights the need for randomised controlled trials comparing direct P2Y12 inhibitor monotherapy with the current standard of care.

Published
2023
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36. A Randomized Comparison of Paclitaxel-Eluting Balloon Versus Everolimus-Eluting Stent for the Treatment of Any In-Stent Restenosis: The DARE Trial

Author

Baan, Jan, Jr., Claessen, Bimmer E., Dijk, Kirsten Boerlage-van, Vendrik, Jeroen, van der Schaaf, René J., Meuwissen, Martijn, van Royen, Niels, Gosselink, A.T. Marcel, van Wely, Marleen H., Dirkali, Atilla, Arkenbout, E. Karin, de Winter, Robbert J., Koch, Karel T., Sjauw, Krischan D., Beijk, Marcel A., Vis, M. Marije, Wykrzykowska, Joanna J., Piek, Jan J., Tijssen, Jan G.P., and Henriques, José P.S.

Published
2018
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37. Higher Edmonton Frail Scale prior to transcatheter Aortic Valve Implantation is related to longer hospital stay and mortality

Author

Holierook, Marja, primary, Henstra, Marieke J., additional, Dolman, Doortje J., additional, Chekanova, Elena V., additional, Veenis, Linda, additional, Beijk, Marcel A.M., additional, de Winter, Robbert J., additional, Baan, Jan, additional, Vis, Marije M., additional, Lemkes, Jorrit S., additional, Snaterse, Marjolein, additional, Henriques, José P.S., additional, and Delewi, Ronak, additional

Published
2023
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40. TCT-408 First-in-Human Drug-Eluting Balloon Treatment of Vulnerable Lipid-Rich Plaques: The DEBuT-LRP Study

Author

van Veelen, Anna, primary, Küçük, I. Tarik, additional, Garcia-Garcia, Hector Manel, additional, Fuentes, Federico, additional, Kahsay, Yirga, additional, Delewi, Ronak, additional, Beijk, Marcel, additional, Hartog, Alexander den, additional, Grundeken, Maik, additional, Vis, M. Marije, additional, Henriques, Jose, additional, and Claessen, Bimmer, additional

Published
2023
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41. Recurrent angina and cardiac ischaemia as a presentation of pheochromocytoma: a case report.

Author

Bovenkamp, Arno A van de, Kalkman, Deborah N, Beijk, Marcel A M, and Veerdonk, Mariëlle C van de

Subjects
ANGINA pectoris, CHEST pain, BLOOD pressure, PHEOCHROMOCYTOMA, PREGNANT women, ACUTE coronary syndrome
Abstract

Background We present a case of a pregnant patient with recurrent angina, in which her symptoms were initially attributed to coronary artery spasm. However, during follow-up, she was diagnosed as having pheochromocytoma, a rare neuroendocrine tumour. Case summary The 35-year-old patient was admitted to the hospital because of chest pain and elevated cardiac troponins after the use of MDMA. Physical examination, electrocardiogram, echocardiography, coronary angiogram, and cardiac MRI were normal. Symptoms were attributed to coronary spasm, and a calcium antagonist was started. Ten months later, when 36 weeks pregnant, her symptoms returned. One week later, the patient was readmitted to the hospital with signs of acute left ventricular (LV) failure, highly elevated troponins, and severe global LV dysfunction. Urgent section caesarean was performed due to maternal morbidity and foetal tachycardia. During section, flushes and marked variability in blood pressure were noted. Laboratory metanephrines testing was performed. LV function recovered within 3 days without any therapeutic intervention. However, chest pain reoccurred, now accompanied with headaches, malignant hypertension, and accelerated idiopathic ventricular rhythms. (Nor)metanephrines tests were positive. A solid lesion in the right adrenal on CT scan confirmed the diagnosis of pheochromocytoma. Fluid repletion and alpha-blocker therapy were started. Due to persistent symptoms, urgent laparoscopic adrenalectomy was performed. Hereafter, the patient remained without symptoms. Discussion A pheochromocytoma may present with recurrent angina and can result in a catecholamine-induced cardiomyopathy. It is important to timely recognize this diagnosis in order to minimize morbidity and mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Impact of coronary hyperemia on collateral flow correction of coronary microvascular resistance indices.

Author

Boerhout, Coen K. M., Veelen, Anna van, Feenstra, Rutger G. T., Jong, Elize A. M. de, Namba, Hanae F., Beijk, Marcel A. M., Henriques, Jose P., Piek, Jan J., and Hoef, Tim P. van de

Subjects
BLOOD flow measurement, HYPEREMIA
Abstract

Recently, a novel method to estimate wedge pressure (Pw)-corrected minimal microvascular resistance (MR) was introduced. However, this method has not been validated since, and there are some theoretical concerns regarding the impact of different physiological conditions on the derivation of Pw measurements. This study sought to validate the recently introduced method to estimate Pw-corrected MR in a Doppler-derived study population and to evaluate the impact of different physiological conditions on the Pw measurements and the derivation of Pw-corrected MR. The method to derive "estimated" hyperemic microvascular resistance (HMR) without the need for Pw measurements was validated by estimating the coronary fractional flow reserve (FFRcor) from myocardial fractional flow reserve (FFRmyo) in a Doppler-derived study population (N = 53). From these patients, 24 had hyperemic Pw measurements available for the evaluation of hyperemic conditions on the derivation of Pw and its effect on the derivation of both "true" (with measured Pw) and "estimated" Pw-corrected HMR. Nonhyperemic Pw differed significantly from Pw measured in hyperemic conditions (26 ± 14 vs. 35 ± 14 mmHg, respectively, P < 0.005). Nevertheless, there was a strong linear relationship between FFRcor and FFRmyo in nonhyperemic conditions (R2 = 0.91, P < 0.005), as well as in hyperemic conditions (R2 = 0.87, P < 0.005). There was a strong linear relationship between "true" HMR and "estimated" HMR using either nonhyperemic (R2 = 0.86, P < 0.005) or hyperemic conditions (R2 = 0.85, P < 0.005) for correction. In contrast to a modest agreement between nonhyperemic Pw-corrected HMR and apparent HMR (R2 = 0.67, P < 0.005), hyperemic Pw-corrected HMR showed a strong agreement with apparent HMR (R2 = 0.88, P < 0.005). We validated the calculation method for Pw-corrected MR in a Doppler velocity-derived population. In addition, we found a significant impact of hyperemic conditions on the measurement of Pw and the derivation of Pw-corrected HMR. NEW & NOTEWORTHY: The following are what is known: 1) wedge-pressure correction is often considered for the derivation of indices of minimal microvascular resistance, and 2) the Yong method for calculating wedge pressure-corrected index of microvascular resistance (IMR) without balloon inflation has never been validated in a Doppler-derived population and has not been tested under different physiological conditions. This study 1) adds validation for the Yong method for calculated wedge-pressure correction in a Doppler-derived study population and 2) shows significant influence of the physiological conditions on the derivation of coronary wedge pressure. [ABSTRACT FROM AUTHOR]

Published
2024
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44. First-in-Human Drug-Eluting Balloon Treatment of Vulnerable Lipid-Rich Plaques: Rationale and Design of the DEBuT-LRP Study

Author

van Veelen, Anna, primary, Küçük, I. Tarik, additional, Fuentes, Federico H., additional, Kahsay, Yirga, additional, Garcia-Garcia, Hector M., additional, Delewi, Ronak, additional, Beijk, Marcel A. M., additional, den Hartog, Alexander W., additional, Grundeken, Maik J., additional, Vis, M. Marije, additional, Henriques, José P. S., additional, and Claessen, Bimmer E. P. M., additional

Published
2023
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46. Post-spastic flow recovery time to document vasospasm induced ischemia during acetylcholine provocation testing

Author

Feenstra, Rutger G.T., primary, Woudstra, Janneke, additional, Bijloo, Isa, additional, Vink, Caitlin E.M., additional, Boerhout, Coen K.M., additional, de Waard, Guus A., additional, Wittekoek, Marianne E., additional, de Winter, Robbert J., additional, Marques, Koen M.J., additional, Eringa, Etto C., additional, van de Hoef, Tim P., additional, Beijk, Marcel A.M., additional, Appelman, Yolande, additional, and Piek, Jan J., additional

Published
2023
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47. Efficacy and safety of the endothelin-1 receptor antagonist macitentan in epicardial and microvascular vasospasm; a proof-of-concept study

Author

Feenstra, Rutger G.T., primary, Jansen, Tijn P.J., additional, Matthijs Boekholdt, S., additional, Brouwer, Janet E., additional, Klees, Margriet I., additional, Appelman, Yolande, additional, Wittekoek, Marianne E., additional, van de Hoef, Tim P., additional, de Winter, Robbert J., additional, Piek, Jan J., additional, Damman, Peter, additional, and Beijk, Marcel A.M., additional

Published
2023
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48. Catheter-Based Techniques for Addressing Atrioventricular Valve Regurgitation in Adult Congenital Heart Disease Patients: A Descriptive Cohort

Author

El Bouziani, Abdelhak, primary, Witte, Lars S., additional, Bouma, Berto J., additional, Jongbloed, Monique R. M., additional, Robbers-Visser, Daniëlle, additional, Straver, Bart, additional, Beijk, Marcel A. M., additional, Kiès, Philippine, additional, Koolbergen, David R., additional, van der Kley, Frank, additional, Schalij, Martin J., additional, de Winter, Robbert J., additional, and Egorova, Anastasia D., additional

Published
2023
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