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p-Si /BaxSr1-xTiO3 heterojunction properties are investigated by electrochemical impedance spectroscopy method for the first time. The general equivalent circuit model is proposed in circuit description code as: Cf, Rf, Ch,Rh,Rp, where Cf, Rf are the BaxSr1-xTiO3 film conditioned capacitance and resistance, Ch, Rh are the heterojunction depletion layer capacitance and resistance, respectively, Rp is the series resistance. It is stated that the Bode plot curves of the structure in air mostly affected by the depletion layer capacitance of heterojunction Ch(V). [ABSTRACT FROM AUTHOR]

Solid-phase synthesis of electrophilic oligodeoxynucleotides (ODNs) was achieved using dimethyl-Dmoc (dM-Dmoc) as amino protecting group. Due to the high steric hindrance of the 2-(propan-2-ylidene)-1,3-dithiane side product from deprotection, the use of excess nucleophilic scavengers such as aniline to prevent Michael addition of the side product to the deprotected ODN during ODN cleavage and deprotection was no longer needed. The improved technology was demonstrated by the synthesis and characterization of five ODNs including three modified ones. The modified ODNs contained the electrophilic groups ethyl ester, α-chloroamide, and thioester. Using the technology, the sensitive groups can be installed at any location within the ODN sequences without using any sequence- or functionality-specific conditions and procedures.

A general approach to C3 modification of purine scaffold through various types of cross-coupling reactions has been established. Tuning substrate electronics and reaction conditions resulted in the development of highly efficient sp 2 -sp, sp 2 -sp 2 , and sp 2 -sp 3 cross-coupling conditions for modification of 3-deazaadenine to access C3-modified adenine and hypoxanthine scaffolds. The optimized methodologies to access the corresponding 3-deazaadenosine phosphoramidites for solid-phase DNA synthesis have been demonstrated., Competing Interests: The authors declare no competing financial interest.